microRNA information: hsa-let-7a-2-3p
| Section | ID | link |
|---|---|---|
| Mature name: | hsa-let-7a-2-3p | miRbase |
| Accession: | MIMAT0010195 | miRbase |
| Precursor name: | hsa-let-7a-2 | miRbase |
| Precursor accession: | MI0000061 | miRbase |
| Symbol: | MIRLET7A2 | HGNC |
| RefSeq ID: | NR_029477 | GenBank |
| Sequence: | CUGUACAGCCUCCUAGCUUUCC |
Reported expression in cancers: hsa-let-7a-2-3p
| miRNA | cancer | regulation | reporting | PUBMED | method |
|---|---|---|---|---|---|
| hsa-let-7a-2-3p | acute myeloid leukemia | upregulation | "Identification of let 7a 2 3p or/and miR 188 5p as ......" | 25646775 | RNA-Seq |
Reported cancer pathway affected by hsa-let-7a-2-3p
| miRNA | cancer | pathway | reporting | PUBMED | functional study |
|---|
Reported cancer prognosis affected by hsa-let-7a-2-3p
| miRNA | cancer | prognosis | reporting | PUBMED | functional study |
|---|---|---|---|---|---|
| hsa-let-7a-2-3p | acute myeloid leukemia | poor survival | "Identification of let 7a 2 3p or/and miR 188 5p as ......" | 25646775 | |
| hsa-let-7a-2-3p | lung cancer | poor survival | "miRNA microarray analysis identified statistical u ......" | 16530703 | |
| hsa-let-7a-2-3p | lung cancer | poor survival | "Tissues were microdissected to obtain >90% tumor o ......" | 27081085 |
Reported gene related to hsa-let-7a-2-3p
| miRNA | cancer | gene | reporting | PUBMED |
|---|---|---|---|---|
| hsa-let-7a-2-3p | acute myeloid leukemia | EFS | "High let-7a-2-3p expression and low miR-188-5p exp ......" | 25646775 |
Expression profile in cancer corhorts:
Putative target regulations
| miRNA | Gene | Cancer | Interaction | Correlation beta |
|---|---|---|---|---|
hsa-let-7a-2-3p | FAM117B | 9 cancers: BLCA; CESC; COAD; HNSC; LGG; LIHC; LUAD; LUSC; PRAD | MirTarget | TCGA BLCA -0.143; TCGA CESC -0.1; TCGA COAD -0.064; TCGA HNSC -0.102; TCGA LGG -0.137; TCGA LIHC -0.132; TCGA LUAD -0.091; TCGA LUSC -0.114; TCGA PRAD -0.143 |
hsa-let-7a-2-3p | HSD17B7 | 12 cancers: BLCA; BRCA; CESC; COAD; KIRC; LGG; LIHC; LUAD; LUSC; OV; PAAD; UCEC | MirTarget | TCGA BLCA -0.055; TCGA BRCA -0.127; TCGA CESC -0.05; TCGA COAD -0.068; TCGA KIRC -0.15; TCGA LGG -0.066; TCGA LIHC -0.077; TCGA LUAD -0.06; TCGA LUSC -0.065; TCGA OV -0.086; TCGA PAAD -0.098; TCGA UCEC -0.066 |
hsa-let-7a-2-3p | ARHGEF10L | 9 cancers: BLCA; CESC; ESCA; HNSC; KIRC; OV; PAAD; SARC; UCEC | MirTarget | TCGA BLCA -0.192; TCGA CESC -0.107; TCGA ESCA -0.204; TCGA HNSC -0.081; TCGA KIRC -0.071; TCGA OV -0.072; TCGA PAAD -0.098; TCGA SARC -0.247; TCGA UCEC -0.054 |
hsa-let-7a-2-3p | CACNA1D | 9 cancers: BLCA; BRCA; CESC; ESCA; HNSC; KIRC; LGG; LIHC; LUAD | MirTarget | TCGA BLCA -0.494; TCGA BRCA -0.201; TCGA CESC -0.276; TCGA ESCA -0.478; TCGA HNSC -0.131; TCGA KIRC -0.119; TCGA LGG -0.121; TCGA LIHC -0.194; TCGA LUAD -0.345 |
hsa-let-7a-2-3p | SRCIN1 | 10 cancers: BLCA; BRCA; CESC; KIRC; KIRP; LUAD; LUSC; PAAD; SARC; THCA | mirMAP | TCGA BLCA -0.426; TCGA BRCA -0.243; TCGA CESC -0.153; TCGA KIRC -0.154; TCGA KIRP -0.313; TCGA LUAD -0.088; TCGA LUSC -0.122; TCGA PAAD -0.497; TCGA SARC -0.164; TCGA THCA -0.571 |
hsa-let-7a-2-3p | TTC39A | 10 cancers: BLCA; BRCA; CESC; ESCA; HNSC; KIRC; LIHC; LUAD; THCA; UCEC | mirMAP | TCGA BLCA -0.117; TCGA BRCA -0.236; TCGA CESC -0.275; TCGA ESCA -0.485; TCGA HNSC -0.192; TCGA KIRC -0.228; TCGA LIHC -0.456; TCGA LUAD -0.1; TCGA THCA -0.246; TCGA UCEC -0.21 |
hsa-let-7a-2-3p | BBC3 | 10 cancers: BRCA; ESCA; KIRC; KIRP; LGG; LIHC; OV; PAAD; THCA; UCEC | MirTarget | TCGA BRCA -0.328; TCGA ESCA -0.19; TCGA KIRC -0.152; TCGA KIRP -0.193; TCGA LGG -0.058; TCGA LIHC -0.187; TCGA OV -0.074; TCGA PAAD -0.213; TCGA THCA -0.163; TCGA UCEC -0.066 |
Enriched cancer pathways of putative targets