Identify the active miRNA-target regulation and infer the regulatory network
in context-specific manner (cancer types or subtypes) by input miRNA symbols and/or gene symbols.
Choose a cancer type of your interest. The public data of the cancer type will be used in learning the correlation between miRNAs and mRNAs (and/or lncRNA) and contruscting the regulatory network. TCGA RNA-seq data and GSE microarray datasets have been applied in this work so far. And the differential expression results of miRNAs and mRNAs have been calculated between high-stage tumors and low-stage tumors.
Optional: compute the differential expression of miRNAs and genes between sample types
Gene | up/down | log2FC | Pvalue |
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miRNA | log2FC | Pvalue |
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