microRNA information: hsa-miR-1246
| Section | ID | link |
|---|---|---|
| Mature name: | hsa-miR-1246 | miRbase |
| Accession: | MIMAT0005898 | miRbase |
| Precursor name: | hsa-mir-1246 | miRbase |
| Precursor accession: | MI0006381 | miRbase |
| Symbol: | MIR1246 | HGNC |
| RefSeq ID: | NR_031648 | GenBank |
| Sequence: | AAUGGAUUUUUGGAGCAGG |
Reported expression in cancers: hsa-miR-1246
| miRNA | cancer | regulation | reporting | PUBMED | method |
|---|---|---|---|---|---|
| hsa-miR-1246 | colon cancer | downregulation | "Microarray analyses of miRNAs in exosome-enriched ......" | 24705249 | Microarray; qPCR |
| hsa-miR-1246 | esophageal cancer | upregulation | "Serum microRNA expression profile: miR 1246 as a n ......" | 23361059 | Microarray |
| hsa-miR-1246 | pancreatic cancer | upregulation | "miRNA was selected according to abundant recovery ......" | 25388097 | Microarray; qPCR |
Reported cancer pathway affected by hsa-miR-1246
| miRNA | cancer | pathway | reporting | PUBMED | functional study |
|---|---|---|---|---|---|
| hsa-miR-1246 | liver cancer | Apoptosis pathway | "p53 induced microRNA 1246 inhibits the cell growth ......" | 25591821 | Colony formation |
| hsa-miR-1246 | lung squamous cell cancer | Epithelial mesenchymal transition pathway | "Hsa miR 1246 and hsa miR 1290 are associated with ......" | 26711929 | Colony formation |
Reported cancer prognosis affected by hsa-miR-1246
| miRNA | cancer | prognosis | reporting | PUBMED | functional study |
|---|---|---|---|---|---|
| hsa-miR-1246 | breast cancer | worse prognosis; drug resistance | "The aim of this study was to investigate the role ......" | 27746365 | |
| hsa-miR-1246 | cervical and endocervical cancer | drug resistance | "The miRNA profiles of radioresistant cells and the ......" | 24283459 | |
| hsa-miR-1246 | cervical and endocervical cancer | progression; tumorigenesis | "MiR 1246 promotes SiHa cervical cancer cell prolif ......" | 24806621 | Wound Healing Assay; Western blot; Luciferase |
| hsa-miR-1246 | cervical and endocervical cancer | staging; metastasis; tumorigenesis | "Down regulation of miR 1246 in cervical cancer tis ......" | 26074491 | Western blot |
| hsa-miR-1246 | colon cancer | staging | "Microarray analyses of miRNAs in exosome-enriched ......" | 24705249 | |
| hsa-miR-1246 | colorectal cancer | metastasis | "MicroRNA 1246 promotes growth and metastasis of co ......" | 26573378 | |
| hsa-miR-1246 | esophageal cancer | staging; poor survival | "Serum microRNA expression profile: miR 1246 as a n ......" | 23361059 | |
| hsa-miR-1246 | liver cancer | staging | "MicroRNA 1246 enhances migration and invasion thro ......" | 25159494 | Luciferase |
| hsa-miR-1246 | liver cancer | tumorigenesis | "p53 induced microRNA 1246 inhibits the cell growth ......" | 25591821 | Colony formation |
| hsa-miR-1246 | liver cancer | metastasis; drug resistance; worse prognosis | "Here we show that human miRNA miR-1246 promotes ca ......" | 27639189 | |
| hsa-miR-1246 | lung cancer | metastasis | "MicroRNA microarrays were performed on 26 primary ......" | 24778034 | |
| hsa-miR-1246 | lung cancer | drug resistance | "Extracellular miR 1246 promotes lung cancer cell p ......" | 27129166 | Luciferase |
| hsa-miR-1246 | lung squamous cell cancer | metastasis; cell migration; worse prognosis | "The microRNA 1246 promotes metastasis in non small ......" | 26209100 | Luciferase; Cell migration assay |
| hsa-miR-1246 | lung squamous cell cancer | metastasis | "Hsa miR 1246 and hsa miR 1290 are associated with ......" | 26711929 | Colony formation |
| hsa-miR-1246 | lung squamous cell cancer | progression; drug resistance | "Tumour initiating cell specific miR 1246 and miR 1 ......" | 27325363 | |
| hsa-miR-1246 | pancreatic cancer | drug resistance; worse prognosis | "MicroRNA 1246 expression associated with CCNG2 med ......" | 25117811 |
Reported gene related to hsa-miR-1246
| miRNA | cancer | gene | reporting | PUBMED |
|---|---|---|---|---|
| hsa-miR-1246 | colorectal cancer | CCNG2 | "MicroRNA 1246 promotes growth and metastasis of co ......" | 26573378 |
| hsa-miR-1246 | pancreatic cancer | CCNG2 | "MicroRNA 1246 expression associated with CCNG2 med ......" | 25117811 |
| hsa-miR-1246 | liver cancer | AXIN2 | "Here we show that human miRNA miR-1246 promotes ca ......" | 27639189 |
| hsa-miR-1246 | liver cancer | CADM1 | "MicroRNA 1246 enhances migration and invasion thro ......" | 25159494 |
| hsa-miR-1246 | lung squamous cell cancer | CPEB4 | "Meanwhile we found that cytoplasmic polyadenylatio ......" | 26209100 |
| hsa-miR-1246 | cervical and endocervical cancer | DYRK1A | "Knock down of HPV16E6 significantly raised DYRK1A ......" | 26074491 |
| hsa-miR-1246 | liver cancer | NFIB | "p53 induced microRNA 1246 inhibits the cell growth ......" | 25591821 |
| hsa-miR-1246 | colorectal cancer | PML | "Colorectal cancer cell derived microvesicles conta ......" | 25218966 |
| hsa-miR-1246 | cervical and endocervical cancer | THBS2 | "MiR 1246 promotes SiHa cervical cancer cell prolif ......" | 24806621 |
| hsa-miR-1246 | lung cancer | TNFRSF10B | "A luciferase reporter-gene transfer experiment dem ......" | 27129166 |
| hsa-miR-1246 | liver cancer | TP53 | "p53 induced microRNA 1246 inhibits the cell growth ......" | 25591821 |