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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-106b-5p ABCA1 0 0 0 0 MirTarget; miRNATAP -0.21 0 NA
2 hsa-miR-106b-5p ABCD2 0 0 0 0 MirTarget -0.8 0 NA
3 hsa-miR-106b-5p ABHD2 0 0 0 0 miRNATAP -0.13 0.00297 NA
4 hsa-miR-106b-5p ABL2 0 0 0 0 MirTarget -0.13 1.0E-5 NA
5 hsa-miR-106b-5p ABTB2 0 0 0 0 miRNAWalker2 validate -0.14 0.0131 NA
6 hsa-miR-106b-5p ADAM19 0 0 0 0 mirMAP -0.7 0 NA
7 hsa-miR-106b-5p ADAM9 0 0 0 0 miRNATAP -0.3 0 NA
8 hsa-miR-106b-5p ADAMTS5 0 0 0 0 miRNATAP -0.52 0 NA
9 hsa-miR-106b-5p ADARB1 0 0 0 0 MirTarget -0.54 0 NA
10 hsa-miR-106b-5p ADCY9 0 0 0 0 mirMAP -0.51 0 NA
11 hsa-miR-106b-5p ADRA2A 0 0 0 0 miRNATAP -0.65 0 NA
12 hsa-miR-106b-5p AFF4 0 0 0 0 miRNATAP -0.11 0.00011 NA
13 hsa-miR-106b-5p AGFG1 0 0 0 0 MirTarget -0.15 0 NA
14 hsa-miR-106b-5p AHNAK 0 0 0 0 miRNATAP -0.55 0 NA
15 hsa-miR-106b-5p AKAP11 0 0 0 0 miRNAWalker2 validate -0.18 0 NA
16 hsa-miR-106b-5p AKAP13 0 0 0 0 MirTarget; mirMAP; miRNATAP -0.34 0 NA
17 hsa-miR-106b-5p AKT3 0 0 0 0 miRNATAP -0.52 0 NA
18 hsa-miR-106b-5p ALDH3A2 0 0 0 0 mirMAP -0.16 0.00048 NA
19 hsa-miR-106b-5p ALPK3 0 0 0 0 mirMAP -0.3 0 NA
20 hsa-miR-106b-5p ANK2 0 0 0 0 MirTarget; miRNATAP -0.94 0 NA
21 hsa-miR-106b-5p ANKH 0 0 0 0 MirTarget -0.43 0 NA
22 hsa-miR-106b-5p ANKRD29 0 0 0 0 MirTarget -1.13 0 NA
23 hsa-miR-106b-5p ANKRD50 0 0 0 0 MirTarget; miRNATAP -0.2 0.00016 NA
24 hsa-miR-106b-5p ANO6 0 0 0 0 MirTarget -0.13 0.00012 NA
25 hsa-miR-106b-5p ANXA11 0 0 0 0 mirMAP -0.15 0 NA
26 hsa-miR-106b-5p APBB2 0 0 0 0 MirTarget; miRNATAP -0.3 0 NA
27 hsa-miR-106b-5p APCDD1 0 0 0 0 MirTarget -0.17 0.00845 NA
28 hsa-miR-106b-5p APP 0 0 0 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.26 0 NA
29 hsa-miR-106b-5p AR 0 0 0 0 mirMAP -0.28 0.02412 NA
30 hsa-miR-106b-5p ARHGAP1 0 0 0 0 MirTarget; miRNATAP -0.36 0 NA
31 hsa-miR-106b-5p ARHGAP24 0 0 0 0 MirTarget -0.67 0 NA
32 hsa-miR-106b-5p ARHGAP26 0 0 0 0 MirTarget; mirMAP; miRNATAP -0.15 0.00134 NA
33 hsa-miR-106b-5p ARHGEF3 0 0 0 0 MirTarget; miRNATAP -0.26 0 NA
34 hsa-miR-106b-5p ARL10 0 0 0 0 mirMAP -0.29 2.0E-5 NA
35 hsa-miR-106b-5p ARL4A 0 0 0 0 miRNATAP -0.15 0.00212 NA
36 hsa-miR-106b-5p ARL4C 0 0 0 0 MirTarget; miRNATAP -0.39 0 NA
37 hsa-miR-106b-5p ARSB 0 0 0 0 mirMAP -0.31 0 NA
38 hsa-miR-106b-5p ASAP1 0 0 0 0 miRNAWalker2 validate -0.1 0.00872 NA
39 hsa-miR-106b-5p ASPA 0 0 0 0 mirMAP -0.68 0 NA
40 hsa-miR-106b-5p ATE1 0 0 0 0 MirTarget -0.15 0.00238 NA
41 hsa-miR-106b-5p ATG16L1 0 0 0 0 MirTarget; miRNATAP -0.11 0 NA
42 hsa-miR-106b-5p ATL3 0 0 0 0 MirTarget; miRNATAP -0.24 0 NA
43 hsa-miR-106b-5p ATP1A2 0 0 0 0 MirTarget; miRNATAP -1.56 0 NA
44 hsa-miR-106b-5p ATP2A2 0 0 0 0 mirMAP -0.11 0.00016 NA
45 hsa-miR-106b-5p ATXN1 0 0 0 0 miRNATAP -0.56 0 NA
46 hsa-miR-106b-5p B3GALT2 0 0 0 0 MirTarget -0.57 0 NA
47 hsa-miR-106b-5p BACH1 0 0 0 0 mirMAP -0.15 2.0E-5 NA
48 hsa-miR-106b-5p BBX 0 0 0 0 MirTarget; miRNATAP -0.16 0 NA
49 hsa-miR-106b-5p BCL2L2 0 0 0 0 miRNATAP -0.25 0 NA
50 hsa-miR-106b-5p BCL9L 0 0 0 0 mirMAP -0.2 0 NA
51 hsa-miR-106b-5p BEND4 0 0 0 0 mirMAP -0.22 0.01818 NA
52 hsa-miR-106b-5p BICD2 0 0 0 0 MirTarget; miRNATAP -0.11 0.00092 NA
53 hsa-miR-106b-5p BMPR2 0 0 0 0 MirTarget; miRNATAP -0.2 0 NA
54 hsa-miR-106b-5p BNC2 0 0 0 0 miRNATAP -1.15 0 NA
55 hsa-miR-106b-5p BNIP3L 0 0 0 0 MirTarget -0.1 0.00077 NA
56 hsa-miR-106b-5p BRMS1L 0 0 0 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.15 0 NA
57 hsa-miR-106b-5p BTG1 0 0 0 0 miRNATAP -0.19 0 NA
58 hsa-miR-106b-5p BTG2 0 0 0 0 miRNATAP -0.15 0.02756 NA
59 hsa-miR-106b-5p BTN3A3 0 0 0 0 miRNAWalker2 validate -0.23 0 NA
60 hsa-miR-106b-5p C14orf28 0 0 0 0 miRNATAP -0.19 0 NA
61 hsa-miR-106b-5p C3orf70 0 0 0 0 miRNATAP -0.3 4.0E-5 NA
62 hsa-miR-106b-5p C4orf3 0 0 0 0 mirMAP -0.17 0 NA
63 hsa-miR-106b-5p CA5B 0 0 0 0 mirMAP -0.12 2.0E-5 NA
64 hsa-miR-106b-5p CADM2 0 0 0 0 MirTarget; miRNATAP -0.24 0.0277 NA
65 hsa-miR-106b-5p CALD1 0 0 0 0 miRNATAP -0.92 0 NA
66 hsa-miR-106b-5p CAMK4 0 0 0 0 mirMAP -0.34 1.0E-5 NA
67 hsa-miR-106b-5p CAV1 0 0 0 0 miRNATAP -0.76 0 NA
68 hsa-miR-106b-5p CAV2 0 0 0 0 mirMAP -0.5 0 NA
69 hsa-miR-106b-5p CBX7 0 0 0 0 mirMAP -0.44 0 NA
70 hsa-miR-106b-5p CCBE1 0 0 0 0 mirMAP -0.38 0.00167 NA
71 hsa-miR-106b-5p CCND1 0 0 0 0 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.19 0.01301 NA
72 hsa-miR-106b-5p CCND2 0 0 0 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.72 0 NA
73 hsa-miR-106b-5p CD274 0 0 0 0 MirTarget; miRNATAP -0.33 0.0004 NA
74 hsa-miR-106b-5p CD28 0 0 0 0 mirMAP -0.57 0 NA
75 hsa-miR-106b-5p CD34 0 0 0 0 miRNAWalker2 validate -0.42 0 NA
76 hsa-miR-106b-5p CD69 0 0 0 0 miRNATAP -0.76 0 NA
77 hsa-miR-106b-5p CDC37L1 0 0 0 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.23 0 NA
78 hsa-miR-106b-5p CDC42EP3 0 0 0 0 mirMAP -0.39 0 NA
79 hsa-miR-106b-5p CDK6 0 0 0 0 mirMAP -0.51 0 NA
80 hsa-miR-106b-5p CDKN1A 0 0 0 0 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.3 0 NA
81 hsa-miR-106b-5p CELF2 0 0 0 0 miRNATAP -0.88 0 NA
82 hsa-miR-106b-5p CERCAM 0 0 0 0 MirTarget -0.27 0 NA
83 hsa-miR-106b-5p CERK 0 0 0 0 mirMAP -0.39 0 NA
84 hsa-miR-106b-5p CES2 0 0 0 0 miRNAWalker2 validate -0.18 0 NA
85 hsa-miR-106b-5p CFL2 0 0 0 0 MirTarget; miRNATAP -0.69 0 NA
86 hsa-miR-106b-5p CHD5 0 0 0 0 MirTarget; miRNATAP -0.31 0.00029 NA
87 hsa-miR-106b-5p CHD9 0 0 0 0 MirTarget; miRNATAP -0.18 0 NA
88 hsa-miR-106b-5p CLIP4 0 0 0 0 MirTarget -0.57 0 NA
89 hsa-miR-106b-5p CLOCK 0 0 0 0 miRNAWalker2 validate; MirTarget -0.1 0.02324 NA
90 hsa-miR-106b-5p CLUAP1 0 0 0 0 mirMAP -0.17 0 NA
91 hsa-miR-106b-5p CNR2 0 0 0 0 mirMAP -0.6 0 NA
92 hsa-miR-106b-5p CNTNAP3 0 0 0 0 MirTarget -0.43 9.0E-5 NA
93 hsa-miR-106b-5p COL1A1 0 0 0 0 mirMAP -0.79 0 NA
94 hsa-miR-106b-5p COL4A3 0 0 0 0 MirTarget; miRNATAP -0.36 0.00266 NA
95 hsa-miR-106b-5p COL8A2 0 0 0 0 mirMAP -0.83 0 NA
96 hsa-miR-106b-5p COMMD6 0 0 0 0 miRNAWalker2 validate -0.11 0.0001 NA
97 hsa-miR-106b-5p CORO2B 0 0 0 0 MirTarget; miRNATAP -0.46 0 NA
98 hsa-miR-106b-5p CPEB3 0 0 0 0 miRNATAP -0.25 0 NA
99 hsa-miR-106b-5p CPEB4 0 0 0 0 mirMAP -0.32 0 NA
100 hsa-miR-106b-5p CPT1A 0 0 0 0 mirMAP -0.16 0.00054 NA
101 hsa-miR-106b-5p CREB5 0 0 0 0 MirTarget; miRNATAP -0.59 0 NA
102 hsa-miR-106b-5p CRIM1 0 0 0 0 MirTarget; miRNATAP -0.16 0.00018 NA
103 hsa-miR-106b-5p CRY2 0 0 0 0 MirTarget; miRNATAP -0.29 0 NA
104 hsa-miR-106b-5p CRYBG3 0 0 0 0 MirTarget; miRNATAP -0.24 0 NA
105 hsa-miR-106b-5p CSF1 0 0 0 0 miRNATAP -0.69 0 NA
106 hsa-miR-106b-5p CSGALNACT1 0 0 0 0 MirTarget -0.5 0 NA
107 hsa-miR-106b-5p CTDSP2 0 0 0 0 miRNAWalker2 validate -0.21 0 NA
108 hsa-miR-106b-5p CTDSPL 0 0 0 0 mirMAP -0.13 3.0E-5 NA
109 hsa-miR-106b-5p CTSA 0 0 0 0 MirTarget -0.11 0.00016 NA
110 hsa-miR-106b-5p CTSK 0 0 0 0 MirTarget -0.84 0 NA
111 hsa-miR-106b-5p CXorf36 0 0 0 0 mirMAP -0.35 0 NA
112 hsa-miR-106b-5p CYBRD1 0 0 0 0 MirTarget -0.84 0 NA
113 hsa-miR-106b-5p CYP26B1 0 0 0 0 miRNATAP -0.28 0.00199 NA
114 hsa-miR-106b-5p CYP2U1 0 0 0 0 MirTarget -0.3 0 NA
115 hsa-miR-106b-5p DAB2 0 0 0 0 MirTarget; miRNATAP -0.38 0 26769181 The expression of the miR-106b target gene DAB2 in human cervical tissues and cell lines were measured by qRT-PCR western blot and immunohistochemistry; DAB2 a predicted target gene of miR-106b was inhibited by TGF-β1 partly through miR-106b and was involved in TGF-β1-induced cervical cancer cell migration; The expression of DAB2 was low in cervical cancer tissues and negatively correlated with miR-106b expression
116 hsa-miR-106b-5p DCBLD2 0 0 0 0 MirTarget; miRNATAP -0.26 0.00026 NA
117 hsa-miR-106b-5p DCUN1D3 0 0 0 0 MirTarget -0.15 0 NA
118 hsa-miR-106b-5p DENND5B 0 0 0 0 MirTarget; miRNATAP -0.35 0 NA
119 hsa-miR-106b-5p DIP2C 0 0 0 0 miRNATAP -0.22 0 NA
120 hsa-miR-106b-5p DIXDC1 0 0 0 0 mirMAP -0.82 0 NA
121 hsa-miR-106b-5p DLC1 0 0 0 0 miRNATAP -0.37 0 26223867 MicroRNA 106b promotes colorectal cancer cell migration and invasion by directly targeting DLC1; Moreover we identify DLC1 as a direct target of miR-106b reveal its expression to be inversely correlated with miR-106b in CRC samples and show that its re-introduction reverses miR-106b-induced CRC cell migration and invasion; Furthermore survival analyses showed the patients with high mi-106b/low DLC1 had shorter overall survival OS and disease-free survival DFS rates and confirmed miR-106b may be an independent prognostic factor for OS and DFS in CRC patients; Our findings indicate that miR-106b promotes CRC cell migration and invasion by targeting DLC1
122 hsa-miR-106b-5p DMD 0 0 0 0 mirMAP -0.83 0 NA
123 hsa-miR-106b-5p DNAJB6 0 0 0 0 miRNAWalker2 validate -0.1 2.0E-5 NA
124 hsa-miR-106b-5p DNAJB9 0 0 0 0 miRNATAP -0.2 0 NA
125 hsa-miR-106b-5p DOCK4 0 0 0 0 MirTarget -0.16 0.00167 NA
126 hsa-miR-106b-5p DPYD 0 0 0 0 MirTarget -0.89 0 NA
127 hsa-miR-106b-5p DPYSL2 0 0 0 0 MirTarget; miRNATAP -0.48 0 NA
128 hsa-miR-106b-5p DRAM1 0 0 0 0 mirMAP -0.32 0 NA
129 hsa-miR-106b-5p DST 0 0 0 0 mirMAP -0.36 0 NA
130 hsa-miR-106b-5p DUSP8 0 0 0 0 MirTarget; miRNATAP -0.41 0 NA
131 hsa-miR-106b-5p ECE1 0 0 0 0 mirMAP -0.22 0 NA
132 hsa-miR-106b-5p EDA2R 0 0 0 0 MirTarget -0.43 0 NA
133 hsa-miR-106b-5p EEA1 0 0 0 0 MirTarget; miRNATAP -0.1 0.00298 NA
134 hsa-miR-106b-5p EEF1A1 0 0 0 0 miRNAWalker2 validate -0.14 0 NA
135 hsa-miR-106b-5p EEF2K 0 0 0 0 mirMAP -0.12 1.0E-5 NA
136 hsa-miR-106b-5p EGR2 0 0 0 0 MirTarget; miRNATAP -0.74 0 NA
137 hsa-miR-106b-5p EIF5A2 0 0 0 0 miRNAWalker2 validate; miRNATAP -0.42 0 NA
138 hsa-miR-106b-5p ELK3 0 0 0 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.35 0 NA
139 hsa-miR-106b-5p ENPP1 0 0 0 0 mirMAP -0.87 0 NA
140 hsa-miR-106b-5p ENTPD1 0 0 0 0 mirMAP -0.38 0 NA
141 hsa-miR-106b-5p EOMES 0 0 0 0 miRNAWalker2 validate; miRTarBase -0.34 0.00034 NA
142 hsa-miR-106b-5p EPAS1 0 0 0 0 miRNATAP -0.26 0 NA
143 hsa-miR-106b-5p EPHA7 0 0 0 0 miRNATAP -0.47 6.0E-5 NA
144 hsa-miR-106b-5p ERAP1 0 0 0 0 MirTarget -0.16 4.0E-5 NA
145 hsa-miR-106b-5p ESYT2 0 0 0 0 mirMAP -0.21 0 NA
146 hsa-miR-106b-5p ETF1 0 0 0 0 miRNATAP -0.15 0 NA
147 hsa-miR-106b-5p ETV1 0 0 0 0 MirTarget; miRNATAP -0.45 0 NA
148 hsa-miR-106b-5p F3 0 0 0 0 MirTarget; miRNATAP -0.68 0 NA
149 hsa-miR-106b-5p FAM102A 0 0 0 0 miRNATAP -0.19 0 NA
150 hsa-miR-106b-5p FAM117A 0 0 0 0 miRNATAP -0.14 0.00023 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 REGULATION OF CELL DIFFERENTIATION 94 1492 4.21e-14 1.959e-10
2 TISSUE DEVELOPMENT 92 1518 7.802e-13 1.815e-09
3 POSITIVE REGULATION OF GENE EXPRESSION 98 1733 7.261e-12 6.757e-09
4 INTRACELLULAR SIGNAL TRANSDUCTION 92 1572 5.571e-12 6.757e-09
5 CELL DEVELOPMENT 86 1426 6.478e-12 6.757e-09
6 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 95 1672 1.251e-11 9.7e-09
7 NEUROGENESIS 84 1402 1.665e-11 1.107e-08
8 MUSCLE STRUCTURE DEVELOPMENT 40 432 3.005e-11 1.748e-08
9 CARDIOVASCULAR SYSTEM DEVELOPMENT 57 788 4.219e-11 1.963e-08
10 CIRCULATORY SYSTEM DEVELOPMENT 57 788 4.219e-11 1.963e-08
11 MUSCLE TISSUE DEVELOPMENT 30 275 1.884e-10 7.97e-08
12 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 94 1784 9.308e-10 3.609e-07
13 REGULATION OF CELL DEVELOPMENT 56 836 1.117e-09 4e-07
14 REGULATION OF CELLULAR COMPONENT MOVEMENT 53 771 1.31e-09 4.355e-07
15 SKELETAL SYSTEM DEVELOPMENT 38 455 1.81e-09 5.614e-07
16 NEURON DIFFERENTIATION 57 874 2.098e-09 6.102e-07
17 RESPONSE TO ENDOGENOUS STIMULUS 80 1450 2.658e-09 7.275e-07
18 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 62 1004 3.251e-09 8.404e-07
19 REGULATION OF ACTIN FILAMENT BASED PROCESS 30 312 3.897e-09 9.544e-07
20 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 94 1848 5.57e-09 1.296e-06
21 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 92 1805 7.582e-09 1.68e-06
22 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 86 1656 1.087e-08 2.3e-06
23 VASCULATURE DEVELOPMENT 37 469 1.365e-08 2.762e-06
24 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 39 513 1.518e-08 2.944e-06
25 REGULATION OF PHOSPHORUS METABOLIC PROCESS 84 1618 1.685e-08 3.135e-06
26 REGULATION OF NEURON DIFFERENTIATION 40 554 4.084e-08 7.309e-06
27 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 59 1008 5.434e-08 9.365e-06
28 BONE DEVELOPMENT 19 156 7.205e-08 1.197e-05
29 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 48 750 7.521e-08 1.207e-05
30 PROTEIN PHOSPHORYLATION 56 944 7.793e-08 1.209e-05
31 EPITHELIUM DEVELOPMENT 56 945 8.074e-08 1.212e-05
32 CONNECTIVE TISSUE DEVELOPMENT 21 194 1.17e-07 1.702e-05
33 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 47 740 1.296e-07 1.827e-05
34 CARTILAGE DEVELOPMENT 18 147 1.463e-07 2.002e-05
35 REGULATION OF CELL ADHESION 42 629 1.63e-07 2.107e-05
36 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 30 368 1.619e-07 2.107e-05
37 NEGATIVE REGULATION OF GENE EXPRESSION 76 1493 1.981e-07 2.443e-05
38 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 49 799 1.995e-07 2.443e-05
39 CELLULAR COMPONENT MORPHOGENESIS 53 900 2.241e-07 2.674e-05
40 REGULATION OF CATABOLIC PROCESS 46 731 2.314e-07 2.691e-05
41 SKELETAL MUSCLE ORGAN DEVELOPMENT 17 137 2.671e-07 3.032e-05
42 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 55 957 2.862e-07 3.17e-05
43 NEURON PROJECTION MORPHOGENESIS 31 402 3.437e-07 3.719e-05
44 REGULATION OF CELL PROJECTION ORGANIZATION 38 558 3.954e-07 4.181e-05
45 BLOOD VESSEL MORPHOGENESIS 29 364 4.208e-07 4.333e-05
46 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 57 1021 4.421e-07 4.333e-05
47 PHOSPHORYLATION 65 1228 4.355e-07 4.333e-05
48 RESPONSE TO MECHANICAL STIMULUS 21 210 4.47e-07 4.333e-05
49 NEGATIVE REGULATION OF CELL DIFFERENTIATION 40 609 4.948e-07 4.699e-05
50 NEURON PROJECTION DEVELOPMENT 37 545 6.076e-07 5.654e-05
51 NEURON DEVELOPMENT 43 687 6.705e-07 6e-05
52 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 55 983 6.667e-07 6e-05
53 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 43 689 7.243e-07 6.292e-05
54 REGULATION OF PROTEIN MODIFICATION PROCESS 82 1710 7.302e-07 6.292e-05
55 MUSCLE CELL DIFFERENTIATION 22 237 8.565e-07 7.246e-05
56 POSITIVE REGULATION OF LOCOMOTION 31 420 8.829e-07 7.336e-05
57 MUSCLE ORGAN DEVELOPMENT 24 277 9.57e-07 7.812e-05
58 HEART DEVELOPMENT 33 466 9.887e-07 7.931e-05
59 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 47 801 1.242e-06 9.798e-05
60 ACTIN FILAMENT BASED PROCESS 32 450 1.321e-06 9.911e-05
61 POSITIVE REGULATION OF MOLECULAR FUNCTION 84 1791 1.291e-06 9.911e-05
62 POSITIVE REGULATION OF CELL DEVELOPMENT 33 472 1.31e-06 9.911e-05
63 REGULATION OF NEURON PROJECTION DEVELOPMENT 30 408 1.433e-06 0.0001059
64 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 74 1517 1.467e-06 0.0001067
65 RESPONSE TO OXYGEN CONTAINING COMPOUND 69 1381 1.505e-06 0.0001077
66 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 90 1977 1.782e-06 0.0001257
67 CELLULAR RESPONSE TO LIPID 32 457 1.837e-06 0.0001276
68 CELLULAR RESPONSE TO ACID CHEMICAL 18 175 1.968e-06 0.0001346
69 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 60 1152 2.115e-06 0.0001426
70 POSITIVE REGULATION OF RESPONSE TO STIMULUS 88 1929 2.178e-06 0.0001448
71 REGULATION OF SYSTEM PROCESS 34 507 2.292e-06 0.0001502
72 CELL PROJECTION ORGANIZATION 50 902 2.873e-06 0.0001857
73 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 16 146 3.179e-06 0.0002006
74 NEGATIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 13 98 3.191e-06 0.0002006
75 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 59 1142 3.331e-06 0.0002066
76 RESPONSE TO WOUNDING 36 563 3.435e-06 0.0002103
77 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 67 1360 3.499e-06 0.0002114
78 POSITIVE REGULATION OF CELL COMMUNICATION 73 1532 4.042e-06 0.0002411
79 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 68 1395 4.207e-06 0.0002478
80 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 24 303 4.609e-06 0.000268
81 RESPONSE TO HORMONE 49 893 4.791e-06 0.0002752
82 POSITIVE REGULATION OF NEURON DIFFERENTIATION 24 306 5.454e-06 0.0003095
83 CENTRAL NERVOUS SYSTEM DEVELOPMENT 48 872 5.523e-06 0.0003096
84 REGULATION OF CELL MORPHOGENESIS 35 552 5.653e-06 0.0003132
85 NEGATIVE REGULATION OF CELL COMMUNICATION 60 1192 6.155e-06 0.0003369
86 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 20 229 6.777e-06 0.0003658
87 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 54 1036 6.918e-06 0.0003658
88 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 54 1036 6.918e-06 0.0003658
89 REGULATION OF CELL SUBSTRATE ADHESION 17 173 7.005e-06 0.0003662
90 DEVELOPMENTAL MATURATION 18 193 7.882e-06 0.0004075
91 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 20 232 8.232e-06 0.0004209
92 RESPONSE TO EXTERNAL STIMULUS 82 1821 8.341e-06 0.0004219
93 ORGAN MORPHOGENESIS 46 841 1.026e-05 0.0005077
94 REGULATION OF OSSIFICATION 17 178 1.024e-05 0.0005077
95 BONE MORPHOGENESIS 11 79 1.134e-05 0.0005505
96 NEGATIVE REGULATION OF CELL PROLIFERATION 38 643 1.136e-05 0.0005505
97 CELLULAR RESPONSE TO RETINOIC ACID 10 65 1.152e-05 0.0005525
98 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 16 162 1.217e-05 0.0005778
99 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 62 1275 1.25e-05 0.0005873
100 BIOLOGICAL ADHESION 53 1032 1.278e-05 0.0005945
101 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 47 876 1.347e-05 0.0006207
102 SKELETAL SYSTEM MORPHOGENESIS 18 201 1.379e-05 0.0006293
103 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 41 724 1.409e-05 0.0006366
104 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 29 437 1.549e-05 0.000693
105 POSITIVE REGULATION OF CELL DEATH 36 605 1.671e-05 0.0007405
106 POSITIVE REGULATION OF CATABOLIC PROCESS 27 395 1.802e-05 0.0007911
107 RESPONSE TO ABIOTIC STIMULUS 52 1024 2.098e-05 0.0009123
108 TELENCEPHALON DEVELOPMENT 19 228 2.221e-05 0.0009567
109 METANEPHRIC NEPHRON DEVELOPMENT 7 32 2.272e-05 0.0009701
110 REGULATION OF ANATOMICAL STRUCTURE SIZE 30 472 2.516e-05 0.001064
111 ANGIOGENESIS 22 293 2.618e-05 0.001098
112 MEMBRANE DEPOLARIZATION DURING CARDIAC MUSCLE CELL ACTION POTENTIAL 5 14 2.652e-05 0.001102
113 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 24 337 2.71e-05 0.001116
114 POSITIVE REGULATION OF CELL DIFFERENTIATION 44 823 2.783e-05 0.001136
115 RESPONSE TO GROWTH FACTOR 30 475 2.832e-05 0.001146
116 ENDOCHONDRAL BONE MORPHOGENESIS 8 45 2.953e-05 0.001184
117 POSITIVE REGULATION OF CATALYTIC ACTIVITY 69 1518 3.523e-05 0.001401
118 CIRCULATORY SYSTEM PROCESS 25 366 3.703e-05 0.00146
119 CHONDROCYTE DIFFERENTIATION 9 60 3.887e-05 0.001507
120 MULTICELLULAR ORGANISMAL SIGNALING 13 123 3.877e-05 0.001507
121 CELL PART MORPHOGENESIS 36 633 4.323e-05 0.001657
122 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 17 199 4.345e-05 0.001657
123 REGULATION OF MAPK CASCADE 37 660 4.586e-05 0.001724
124 KIDNEY EPITHELIUM DEVELOPMENT 13 125 4.596e-05 0.001724
125 CELLULAR RESPONSE TO OXYGEN LEVELS 14 143 4.65e-05 0.001731
126 LOCOMOTION 54 1114 5.11e-05 0.001887
127 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 24 352 5.429e-05 0.001989
128 NEGATIVE REGULATION OF PHOSPHORYLATION 27 422 5.674e-05 0.002062
129 WOUND HEALING 29 470 5.829e-05 0.002092
130 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 16 184 5.856e-05 0.002092
131 MUSCLE CELL DEVELOPMENT 13 128 5.891e-05 0.002092
132 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 14 147 6.299e-05 0.002207
133 NEURON PROJECTION GUIDANCE 17 205 6.31e-05 0.002207
134 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 67 1492 6.666e-05 0.002315
135 FOREBRAIN DEVELOPMENT 24 357 6.772e-05 0.002334
136 REGULATION OF CELL PROLIFERATION 67 1496 7.222e-05 0.002471
137 REGULATION OF CELLULAR COMPONENT SIZE 23 337 7.61e-05 0.002579
138 REGULATION OF PRI MIRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 5 17 7.647e-05 0.002579
139 CELLULAR RESPONSE TO HORMONE STIMULUS 32 552 8.028e-05 0.002687
140 REGULATION OF VASOCONSTRICTION 9 66 8.396e-05 0.00279
141 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 16 190 8.584e-05 0.002813
142 REGULATION OF BLOOD CIRCULATION 21 295 8.557e-05 0.002813
143 MEMBRANE DEPOLARIZATION DURING ACTION POTENTIAL 7 39 8.775e-05 0.002835
144 NEGATIVE REGULATION OF CELL CYCLE 27 433 8.745e-05 0.002835
145 PALLIUM DEVELOPMENT 14 153 9.723e-05 0.00312
146 REGULATION OF MEMBRANE POTENTIAL 23 343 9.92e-05 0.003141
147 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 8 53 9.991e-05 0.003141
148 SKELETAL MUSCLE CELL DIFFERENTIATION 8 53 9.991e-05 0.003141
149 STRIATED MUSCLE CELL DIFFERENTIATION 15 173 0.0001022 0.003192
150 NEGATIVE REGULATION OF CELL CYCLE PROCESS 17 214 0.0001072 0.003326
151 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 20 278 0.0001086 0.003346
152 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 34 616 0.0001251 0.00383
153 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 31 541 0.0001275 0.003853
154 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 31 541 0.0001275 0.003853
155 REGULATION OF RESPONSE TO STRESS 65 1468 0.0001294 0.003886
156 REGULATION OF POSTSYNAPTIC MEMBRANE POTENTIAL 8 55 0.0001307 0.003899
157 REGULATION OF CIRCADIAN RHYTHM 11 103 0.0001375 0.004023
158 KIDNEY VASCULATURE DEVELOPMENT 5 19 0.0001372 0.004023
159 RENAL SYSTEM VASCULATURE DEVELOPMENT 5 19 0.0001372 0.004023
160 REGULATION OF KINASE ACTIVITY 40 776 0.0001406 0.004064
161 REGULATION OF CELL DEATH 65 1472 0.0001398 0.004064
162 EPITHELIAL CELL DIFFERENTIATION 29 495 0.0001436 0.004126
163 REGULATION OF GTPASE ACTIVITY 36 673 0.000148 0.004224
164 CEREBRAL CORTEX DEVELOPMENT 11 105 0.0001634 0.004635
165 HOMEOSTATIC PROCESS 60 1337 0.0001671 0.00469
166 PROTEIN LOCALIZATION 76 1805 0.0001673 0.00469
167 RESPONSE TO OXYGEN LEVELS 21 311 0.0001788 0.004952
168 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 25 404 0.000178 0.004952
169 TUBE DEVELOPMENT 31 552 0.0001822 0.005018
170 PLASMA MEMBRANE ORGANIZATION 16 203 0.0001856 0.00508
171 HEAD DEVELOPMENT 37 709 0.0001958 0.005328
172 MESONEPHROS DEVELOPMENT 10 90 0.0001979 0.005355
173 REGULATION OF BODY FLUID LEVELS 29 506 0.0002083 0.005602
174 REGULATION OF ACTIN FILAMENT BASED MOVEMENT 6 32 0.0002199 0.005881
175 REGULATION OF CELLULAR COMPONENT BIOGENESIS 39 767 0.0002243 0.005965
176 REGULATION OF MEMBRANE PROTEIN ECTODOMAIN PROTEOLYSIS 5 21 0.0002294 0.006064
177 REGULATION OF CATION TRANSMEMBRANE TRANSPORT 16 208 0.0002449 0.006438
178 CELLULAR RESPONSE TO STRESS 67 1565 0.0002656 0.006942
179 IMMUNE SYSTEM PROCESS 81 1984 0.0002694 0.007003
180 MEMBRANE DEPOLARIZATION 8 61 0.0002733 0.007041
181 RHYTHMIC PROCESS 20 298 0.0002739 0.007041
182 ENDOMEMBRANE SYSTEM ORGANIZATION 27 465 0.0002781 0.007111
183 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 52 1135 0.0002836 0.007211
184 UROGENITAL SYSTEM DEVELOPMENT 20 299 0.0002861 0.007235
185 CELL MATURATION 12 131 0.0002983 0.007504
186 RESPONSE TO LIPID 43 888 0.0003087 0.007721
187 RESPONSE TO FLUID SHEAR STRESS 6 34 0.0003114 0.007748
188 RESPONSE TO STEROID HORMONE 28 497 0.0003513 0.008694
189 REGULATION OF CARDIAC MUSCLE CONTRACTION BY CALCIUM ION SIGNALING 5 23 0.0003622 0.008862
190 SCF DEPENDENT PROTEASOMAL UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 5 23 0.0003622 0.008862
191 NEPHRON DEVELOPMENT 11 115 0.0003638 0.008862
192 CELLULAR RESPONSE TO MECHANICAL STIMULUS 9 80 0.0003731 0.009005
193 RESPONSE TO OXIDATIVE STRESS 22 352 0.0003735 0.009005
194 REGULATION OF MUSCLE SYSTEM PROCESS 15 195 0.0003791 0.009092
195 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 32 602 0.0003813 0.009098
196 GLOMERULUS DEVELOPMENT 7 49 0.0003856 0.009153
197 CHEMICAL HOMEOSTASIS 42 874 0.0004233 0.009947
198 REGULATION OF RECEPTOR ACTIVITY 11 117 0.0004221 0.009947
NumGOOverlapSizeP ValueAdj. P Value
1 ENZYME BINDING 98 1737 8.293e-12 7.704e-09
2 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 29 328 4.584e-08 2.129e-05
3 CYTOSKELETAL PROTEIN BINDING 50 819 1.707e-07 5.287e-05
4 KINASE BINDING 40 606 4.361e-07 8.102e-05
5 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 22 226 3.802e-07 8.102e-05
6 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 26 315 8.58e-07 0.0001075
7 KINASE ACTIVITY 49 842 9.256e-07 0.0001075
8 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 63 1199 8.555e-07 0.0001075
9 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 40 629 1.12e-06 0.0001156
10 PROTEIN DIMERIZATION ACTIVITY 59 1149 4.025e-06 0.0003294
11 PROTEIN KINASE ACTIVITY 39 640 4.255e-06 0.0003294
12 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 53 992 4.188e-06 0.0003294
13 ACTIN BINDING 28 393 5.849e-06 0.000418
14 MACROMOLECULAR COMPLEX BINDING 67 1399 8.918e-06 0.0005918
15 VOLTAGE GATED SODIUM CHANNEL ACTIVITY 6 20 1.249e-05 0.0007736
16 PROTEIN DOMAIN SPECIFIC BINDING 37 624 1.378e-05 0.0008002
17 IDENTICAL PROTEIN BINDING 59 1209 1.856e-05 0.001014
18 REGULATORY REGION NUCLEIC ACID BINDING 44 818 2.405e-05 0.001241
19 BINDING BRIDGING 16 173 2.766e-05 0.001352
20 TRANSCRIPTION FACTOR BINDING 32 524 2.981e-05 0.001385
21 RECEPTOR BINDING 67 1476 4.815e-05 0.00213
22 PROTEIN HOMODIMERIZATION ACTIVITY 39 722 6.406e-05 0.002705
23 PROTEIN COMPLEX BINDING 47 935 6.768e-05 0.002734
24 RIBONUCLEOTIDE BINDING 79 1860 9.244e-05 0.003578
25 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 33 588 0.0001151 0.004278
26 MOLECULAR FUNCTION REGULATOR 61 1353 0.0001296 0.004631
27 CALMODULIN BINDING 15 179 0.0001496 0.005147
28 MAP KINASE KINASE KINASE ACTIVITY 5 22 0.0002901 0.009624
NumGOOverlapSizeP ValueAdj. P Value
1 ACTIN CYTOSKELETON 38 444 9.116e-10 5.324e-07
2 CYTOSKELETON 99 1967 3.468e-09 6.751e-07
3 MEMBRANE MICRODOMAIN 29 288 2.477e-09 6.751e-07
4 MEMBRANE REGION 65 1134 2.378e-08 3.472e-06
5 CELL LEADING EDGE 29 350 1.85e-07 2.161e-05
6 CELL PROJECTION 86 1786 3.132e-07 3.048e-05
7 ANCHORING JUNCTION 34 489 1.025e-06 8.549e-05
8 NEURON PROJECTION 52 942 2.033e-06 0.0001484
9 CELL SUBSTRATE JUNCTION 29 398 2.569e-06 0.0001667
10 NEURON PART 63 1265 4.982e-06 0.0002909
11 CELL JUNCTION 58 1151 8.601e-06 0.0004566
12 SIDE OF MEMBRANE 29 428 1.048e-05 0.0005099
13 INTRINSIC COMPONENT OF PLASMA MEMBRANE 75 1649 1.519e-05 0.0006826
14 VACUOLE 58 1180 1.784e-05 0.0007121
15 AXON 28 418 1.829e-05 0.0007121
16 BASAL PLASMA MEMBRANE 7 33 2.816e-05 0.0008588
17 VOLTAGE GATED SODIUM CHANNEL COMPLEX 5 14 2.652e-05 0.0008588
18 LAMELLIPODIUM 16 172 2.575e-05 0.0008588
19 MAIN AXON 9 58 2.941e-05 0.0008588
20 PLASMA MEMBRANE RAFT 11 86 2.578e-05 0.0008588
21 SITE OF POLARIZED GROWTH 14 149 7.3e-05 0.001942
22 SODIUM CHANNEL COMPLEX 5 17 7.647e-05 0.001942
23 BASAL PART OF CELL 8 51 7.536e-05 0.001942
24 CONTRACTILE FIBER 17 211 9.019e-05 0.002107
25 CELL PROJECTION PART 47 946 8.939e-05 0.002107
26 CORTICAL ACTIN CYTOSKELETON 8 58 0.0001913 0.004228
27 INTRACELLULAR VESICLE 57 1259 0.0001955 0.004228
28 EXTRINSIC COMPONENT OF MEMBRANE 18 252 0.0002581 0.005383
29 SCF UBIQUITIN LIGASE COMPLEX 6 34 0.0003114 0.006239
30 SYNAPSE 38 754 0.0003205 0.006239
31 CYTOSKELETAL PART 62 1436 0.0003655 0.006886
32 PLASMA MEMBRANE REGION 44 929 0.0004209 0.007445
33 RUFFLE 13 156 0.0004283 0.007445
34 ENDOSOME 39 793 0.0004335 0.007445
35 COATED PIT 8 67 0.0005234 0.008733
36 I BAND 11 121 0.0005624 0.008876
37 PERINUCLEAR REGION OF CYTOPLASM 33 642 0.0005588 0.008876

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Cellular_senescence_hsa04218 14 160 0.0001567 0.005849
2 FoxO_signaling_pathway_hsa04068 12 132 0.0003201 0.005849
3 PI3K_Akt_signaling_pathway_hsa04151 22 352 0.0003735 0.005849
4 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 12 139 0.0005131 0.005849
5 AMPK_signaling_pathway_hsa04152 11 121 0.0005624 0.005849
6 TNF_signaling_pathway_hsa04668 10 108 0.0008593 0.007447
7 Hippo_signaling_pathway_hsa04390 12 154 0.001268 0.009091
8 Focal_adhesion_hsa04510 14 199 0.001399 0.009091
9 Jak_STAT_signaling_pathway_hsa04630 12 162 0.001951 0.01127
10 p53_signaling_pathway_hsa04115 7 68 0.002767 0.01439
11 Autophagy_animal_hsa04140 10 128 0.003081 0.01456
12 MAPK_signaling_pathway_hsa04010 17 295 0.003862 0.01674
13 cGMP_PKG_signaling_pathway_hsa04022 11 163 0.005978 0.02391
14 Hippo_signaling_pathway_multiple_species_hsa04392 4 29 0.008083 0.03002
15 HIF_1_signaling_pathway_hsa04066 7 100 0.02152 0.0746
16 Apelin_signaling_pathway_hsa04371 8 137 0.03772 0.1164
17 Endocytosis_hsa04144 12 244 0.04082 0.1164
18 Sphingolipid_signaling_pathway_hsa04071 7 118 0.04668 0.1164
19 Cell_adhesion_molecules_.CAMs._hsa04514 8 145 0.04982 0.1164
20 Adherens_junction_hsa04520 5 72 0.04993 0.1164
21 cAMP_signaling_pathway_hsa04024 10 198 0.05057 0.1164
22 Phospholipase_D_signaling_pathway_hsa04072 8 146 0.05149 0.1164
23 Wnt_signaling_pathway_hsa04310 8 146 0.05149 0.1164
24 Oocyte_meiosis_hsa04114 7 124 0.05805 0.1207
25 Ras_signaling_pathway_hsa04014 11 232 0.06025 0.1207
26 mTOR_signaling_pathway_hsa04150 8 151 0.06037 0.1207
27 Calcium_signaling_pathway_hsa04020 9 182 0.06836 0.1316
28 ECM_receptor_interaction_hsa04512 5 82 0.07817 0.1452
29 TGF_beta_signaling_pathway_hsa04350 5 84 0.08467 0.1518
30 ErbB_signaling_pathway_hsa04012 5 85 0.08802 0.1526
31 Mitophagy_animal_hsa04137 4 65 0.1068 0.1791
32 Regulation_of_actin_cytoskeleton_hsa04810 9 208 0.127 0.2064
33 Hedgehog_signaling_pathway_hsa04340 3 47 0.1419 0.2236
34 Tight_junction_hsa04530 7 170 0.1957 0.2993
35 Rap1_signaling_pathway_hsa04015 8 206 0.2161 0.3135
36 Cytokine_cytokine_receptor_interaction_hsa04060 10 270 0.2206 0.3135
37 VEGF_signaling_pathway_hsa04370 3 59 0.2256 0.3135
38 Gap_junction_hsa04540 4 88 0.2291 0.3135
39 Phagosome_hsa04145 6 152 0.2487 0.3316
40 Lysosome_hsa04142 5 123 0.2575 0.3333
41 Cell_cycle_hsa04110 5 124 0.2628 0.3333
42 Ferroptosis_hsa04216 2 40 0.306 0.3788
43 Apoptosis_hsa04210 5 138 0.3386 0.4095
44 ABC_transporters_hsa02010 2 45 0.3571 0.422
45 Phosphatidylinositol_signaling_system_hsa04070 3 99 0.5221 0.6033
46 Necroptosis_hsa04217 4 164 0.6723 0.7438
47 Neuroactive_ligand_receptor_interaction_hsa04080 4 278 0.9525 0.9906

Quest ID: dcb1dace3f23c2bdb190b113e549b9cb