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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-361-5p ABCA1 -0.65 0 -0.11 0.40751 miRanda; mirMAP -0.29 0.00018 NA
2 hsa-miR-361-5p ABCB10 -0.65 0 0.11 0.11119 MirTarget; miRanda -0.16 9.0E-5 NA
3 hsa-miR-361-5p ABCD2 -0.65 0 1.33 0 miRanda -0.7 0 NA
4 hsa-miR-361-5p ABI2 -0.65 0 0.18 0.00137 miRanda -0.17 0 NA
5 hsa-miR-361-5p ABL1 -0.65 0 0.05 0.42981 miRanda -0.1 0.00538 NA
6 hsa-miR-361-5p ACACB -0.65 0 1.1 0 miRanda -0.2 0.00904 NA
7 hsa-miR-361-5p ACAP2 -0.65 0 0.26 0.00083 miRanda; mirMAP; miRNATAP -0.24 0 NA
8 hsa-miR-361-5p ACBD5 -0.65 0 -0.14 0.05512 miRanda -0.11 0.02033 NA
9 hsa-miR-361-5p ACER3 -0.65 0 -0.26 0.08177 mirMAP -0.49 0 NA
10 hsa-miR-361-5p ACSL6 -0.65 0 1.58 0 miRanda -0.62 0 NA
11 hsa-miR-361-5p ACTC1 -0.65 0 3.4 0 miRanda; miRNATAP -0.85 0.00022 NA
12 hsa-miR-361-5p ACTN4 -0.65 0 0.43 0 miRanda -0.2 0 NA
13 hsa-miR-361-5p ADAM10 -0.65 0 0.28 0.07197 miRanda -0.56 0 NA
14 hsa-miR-361-5p ADAM19 -0.65 0 0.86 0 miRanda -0.27 0.00381 NA
15 hsa-miR-361-5p ADAM22 -0.65 0 1.06 1.0E-5 mirMAP -0.77 0 NA
16 hsa-miR-361-5p ADAM28 -0.65 0 1.23 0 mirMAP -0.6 0 NA
17 hsa-miR-361-5p ADAMTS5 -0.65 0 1.91 0 PITA; miRanda -0.78 0 NA
18 hsa-miR-361-5p ADCY9 -0.65 0 0.73 0 miRanda -0.36 0 NA
19 hsa-miR-361-5p ADD3 -0.65 0 0.99 0 MirTarget; PITA; miRanda; miRNATAP -0.36 6.0E-5 NA
20 hsa-miR-361-5p ADNP -0.65 0 -0.03 0.67622 miRanda -0.14 0.00429 NA
21 hsa-miR-361-5p ADSS -0.65 0 0.05 0.42961 miRanda -0.19 0 NA
22 hsa-miR-361-5p AEBP2 -0.65 0 0.32 0 MirTarget; PITA; miRanda -0.14 8.0E-5 NA
23 hsa-miR-361-5p AFF2 -0.65 0 1.9 0 PITA; mirMAP -0.71 0 NA
24 hsa-miR-361-5p AFF4 -0.65 0 0.21 0.01507 miRanda -0.28 0 NA
25 hsa-miR-361-5p AGL -0.65 0 0.51 0 miRanda -0.33 0 NA
26 hsa-miR-361-5p AGPS -0.65 0 0.88 0 miRanda; miRNATAP -0.41 0 NA
27 hsa-miR-361-5p AGR2 -0.65 0 -0.57 0.01438 miRanda -0.29 0.04234 NA
28 hsa-miR-361-5p AHCYL2 -0.65 0 0.09 0.27752 miRanda -0.17 0.00095 NA
29 hsa-miR-361-5p AHNAK -0.65 0 0.45 5.0E-5 miRanda -0.41 0 NA
30 hsa-miR-361-5p AJAP1 -0.65 0 1.01 0 miRanda -0.44 0.00076 NA
31 hsa-miR-361-5p AK3 -0.65 0 0.2 0.00026 miRanda -0.1 0.00174 NA
32 hsa-miR-361-5p AKAP11 -0.65 0 0.67 0 mirMAP -0.39 0 NA
33 hsa-miR-361-5p AKAP5 -0.65 0 -0.19 0.15744 miRanda -0.21 0.01316 NA
34 hsa-miR-361-5p AKAP6 -0.65 0 0.91 0 miRanda -0.3 0.0008 NA
35 hsa-miR-361-5p ALDH1L2 -0.65 0 1.86 0 miRanda; mirMAP; miRNATAP -0.69 0 NA
36 hsa-miR-361-5p ALDH6A1 -0.65 0 -0.22 0.08256 miRanda; miRNATAP -0.2 0.00876 NA
37 hsa-miR-361-5p AMBRA1 -0.65 0 0.04 0.36283 miRanda -0.12 2.0E-5 NA
38 hsa-miR-361-5p AMFR -0.65 0 0.31 0 miRanda -0.16 0 NA
39 hsa-miR-361-5p AMIGO2 -0.65 0 0.96 0 miRanda -0.34 0.00071 NA
40 hsa-miR-361-5p ANGPT1 -0.65 0 2.4 0 miRanda -0.8 0 NA
41 hsa-miR-361-5p ANGPTL2 -0.65 0 0.68 0 miRanda -0.37 3.0E-5 NA
42 hsa-miR-361-5p ANKFY1 -0.65 0 0.17 0.00776 miRanda -0.22 0 NA
43 hsa-miR-361-5p ANKRD12 -0.65 0 0.3 0.00012 miRanda -0.23 0 NA
44 hsa-miR-361-5p ANKRD17 -0.65 0 0.05 0.56613 miRanda -0.29 0 NA
45 hsa-miR-361-5p ANKRD34B -0.65 0 -2.97 0 MirTarget; miRanda -0.66 0.03915 NA
46 hsa-miR-361-5p ANKRD42 -0.65 0 0.28 0 miRanda -0.12 0.0001 NA
47 hsa-miR-361-5p ANKRD44 -0.65 0 0.89 0 miRanda -0.57 0 NA
48 hsa-miR-361-5p ANO1 -0.65 0 1.77 0 miRanda; miRNATAP -0.71 0 NA
49 hsa-miR-361-5p ANO3 -0.65 0 0.1 0.73748 miRanda -0.37 0.03443 NA
50 hsa-miR-361-5p ANO6 -0.65 0 1.4 0 MirTarget; miRanda -0.49 0 NA
51 hsa-miR-361-5p AOC3 -0.65 0 1.08 0 MirTarget; miRanda -0.34 0.00059 NA
52 hsa-miR-361-5p AP1S2 -0.65 0 0.58 0 miRanda -0.2 0.0005 NA
53 hsa-miR-361-5p AP1S3 -0.65 0 -0.01 0.95392 miRanda -0.29 1.0E-5 NA
54 hsa-miR-361-5p AP3B1 -0.65 0 0.22 0.00076 miRanda -0.26 0 NA
55 hsa-miR-361-5p APH1B -0.65 0 -0.03 0.73374 miRanda -0.15 0.00134 NA
56 hsa-miR-361-5p APPBP2 -0.65 0 0.1 0.10538 PITA; miRanda -0.23 0 NA
57 hsa-miR-361-5p AQP9 -0.65 0 1.39 0 miRanda -0.65 0 NA
58 hsa-miR-361-5p AR -0.65 0 0.44 0.04112 mirMAP -0.52 6.0E-5 NA
59 hsa-miR-361-5p ARCN1 -0.65 0 0.03 0.63018 miRNAWalker2 validate; PITA; miRanda; miRNATAP -0.15 1.0E-5 NA
60 hsa-miR-361-5p ARF4 -0.65 0 -0.14 0.02364 miRNAWalker2 validate; miRanda -0.1 0.00614 NA
61 hsa-miR-361-5p ARFGEF2 -0.65 0 0.32 0.00076 miRanda -0.35 0 NA
62 hsa-miR-361-5p ARHGAP20 -0.65 0 1.96 0 miRanda -0.82 0 NA
63 hsa-miR-361-5p ARHGAP21 -0.65 0 0.16 0.02238 miRanda -0.22 0 NA
64 hsa-miR-361-5p ARHGAP31 -0.65 0 0.55 0 mirMAP -0.41 0 NA
65 hsa-miR-361-5p ARHGAP42 -0.65 0 0.38 0.00337 miRanda -0.32 4.0E-5 NA
66 hsa-miR-361-5p ARHGEF12 -0.65 0 0.23 0.00506 miRNATAP -0.3 0 NA
67 hsa-miR-361-5p ARHGEF6 -0.65 0 0.49 1.0E-5 miRanda -0.23 0.00054 NA
68 hsa-miR-361-5p ARHGEF9 -0.65 0 0.61 0 miRanda -0.18 4.0E-5 NA
69 hsa-miR-361-5p ARID1A -0.65 0 -0.13 0.09882 miRanda -0.13 0.00542 NA
70 hsa-miR-361-5p ARID2 -0.65 0 0.15 0.02675 MirTarget; PITA; miRanda -0.22 0 NA
71 hsa-miR-361-5p ARID4A -0.65 0 0.39 0 miRanda -0.23 0 NA
72 hsa-miR-361-5p ARIH1 -0.65 0 0.12 0.01391 miRanda -0.19 0 NA
73 hsa-miR-361-5p ARL1 -0.65 0 0.12 0.02491 miRanda -0.18 0 NA
74 hsa-miR-361-5p ARL10 -0.65 0 1.23 0 mirMAP -0.44 1.0E-5 NA
75 hsa-miR-361-5p ARL13B -0.65 0 0.07 0.44506 miRanda -0.2 0.00027 NA
76 hsa-miR-361-5p ARL4C -0.65 0 0.78 0 miRanda -0.24 0.00095 NA
77 hsa-miR-361-5p ARMC8 -0.65 0 0.23 1.0E-5 PITA; miRanda; miRNATAP -0.14 1.0E-5 NA
78 hsa-miR-361-5p ARNT -0.65 0 0.21 3.0E-5 miRanda -0.18 0 NA
79 hsa-miR-361-5p ARNTL -0.65 0 0.59 0 miRanda -0.17 0.006 NA
80 hsa-miR-361-5p ARRDC3 -0.65 0 0.49 2.0E-5 MirTarget; PITA; miRanda; miRNATAP -0.35 0 NA
81 hsa-miR-361-5p ARSB -0.65 0 0.32 0.00016 miRanda -0.41 0 NA
82 hsa-miR-361-5p ASAP2 -0.65 0 0.12 0.1751 miRanda -0.27 0 NA
83 hsa-miR-361-5p ASB7 -0.65 0 0.11 0.02221 miRanda -0.13 1.0E-5 NA
84 hsa-miR-361-5p ASCC3 -0.65 0 0.35 0.00431 miRanda -0.41 0 NA
85 hsa-miR-361-5p ASF1A -0.65 0 0.22 0.01618 miRanda -0.12 0.02969 NA
86 hsa-miR-361-5p ASH1L -0.65 0 0.37 0.0002 miRNAWalker2 validate -0.37 0 NA
87 hsa-miR-361-5p ASPH -0.65 0 1.11 0 miRanda -0.47 0 NA
88 hsa-miR-361-5p ASTN1 -0.65 0 2.02 0 miRanda -0.62 0.00073 NA
89 hsa-miR-361-5p ASXL3 -0.65 0 1.72 0 mirMAP -0.55 2.0E-5 NA
90 hsa-miR-361-5p ATF2 -0.65 0 0.55 4.0E-5 miRanda -0.52 0 NA
91 hsa-miR-361-5p ATF3 -0.65 0 1.01 0.00012 miRanda -0.37 0.02168 NA
92 hsa-miR-361-5p ATF7 -0.65 0 0.07 0.28145 mirMAP -0.25 0 NA
93 hsa-miR-361-5p ATG5 -0.65 0 0.45 0 miRanda -0.19 0.00158 NA
94 hsa-miR-361-5p ATL2 -0.65 0 0.4 0 miRanda -0.21 0 NA
95 hsa-miR-361-5p ATL3 -0.65 0 0.24 0.02942 mirMAP -0.35 0 NA
96 hsa-miR-361-5p ATP6V1A -0.65 0 -0.09 0.21178 miRNAWalker2 validate -0.15 0.00035 NA
97 hsa-miR-361-5p ATP7A -0.65 0 0.12 0.16166 miRanda -0.21 8.0E-5 NA
98 hsa-miR-361-5p ATP9A -0.65 0 0.16 0.03136 miRanda -0.32 0 NA
99 hsa-miR-361-5p ATR -0.65 0 -0.26 0.00138 miRanda -0.12 0.01466 NA
100 hsa-miR-361-5p ATRNL1 -0.65 0 1.7 0 miRanda -0.45 0.00089 NA
101 hsa-miR-361-5p ATXN1L -0.65 0 0.43 0 miRanda -0.33 0 NA
102 hsa-miR-361-5p AVL9 -0.65 0 -0.23 0.04984 miRanda -0.23 0.00113 NA
103 hsa-miR-361-5p AXL -0.65 0 0.75 0 miRanda -0.29 0.00014 NA
104 hsa-miR-361-5p B2M -0.65 0 0.2 0.04836 miRanda -0.13 0.0376 NA
105 hsa-miR-361-5p B3GALNT1 -0.65 0 0.56 5.0E-5 miRanda -0.52 0 NA
106 hsa-miR-361-5p B4GALT6 -0.65 0 0.82 0 MirTarget; miRanda -0.33 0 NA
107 hsa-miR-361-5p BACH1 -0.65 0 -0.18 0.04671 miRanda; mirMAP -0.17 0.00187 NA
108 hsa-miR-361-5p BAZ2B -0.65 0 0.33 2.0E-5 miRanda -0.19 3.0E-5 NA
109 hsa-miR-361-5p BBS10 -0.65 0 0.3 0.00018 miRanda -0.25 0 NA
110 hsa-miR-361-5p BBX -0.65 0 0.86 0 PITA; miRanda; mirMAP -0.47 0 NA
111 hsa-miR-361-5p BCOR -0.65 0 -0.28 0.00771 miRanda -0.23 0.00036 NA
112 hsa-miR-361-5p BCORL1 -0.65 0 0.26 0.00303 MirTarget; PITA; miRanda; miRNATAP -0.3 0 NA
113 hsa-miR-361-5p BDNF -0.65 0 1.66 0 PITA; miRanda; miRNATAP -0.47 0.00023 NA
114 hsa-miR-361-5p BDP1 -0.65 0 0.16 0.12278 miRanda; mirMAP -0.24 0.00014 NA
115 hsa-miR-361-5p BEND7 -0.65 0 0.36 0.00534 mirMAP -0.43 0 NA
116 hsa-miR-361-5p BLZF1 -0.65 0 0.38 0 miRanda -0.25 0 NA
117 hsa-miR-361-5p BMP2K -0.65 0 0.18 0.09946 miRanda -0.3 0 NA
118 hsa-miR-361-5p BMP3 -0.65 0 0.66 0.018 miRanda; mirMAP -0.5 0.00306 NA
119 hsa-miR-361-5p BMP7 -0.65 0 1.55 0 miRanda -0.65 2.0E-5 NA
120 hsa-miR-361-5p BMPR2 -0.65 0 0.33 8.0E-5 MirTarget; miRanda; mirMAP; miRNATAP -0.35 0 NA
121 hsa-miR-361-5p BNIP3L -0.65 0 0.75 0 PITA; miRanda -0.43 0 NA
122 hsa-miR-361-5p BRIP1 -0.65 0 0.08 0.67378 miRanda -0.26 0.02267 NA
123 hsa-miR-361-5p BRPF3 -0.65 0 0.06 0.58503 miRanda -0.23 0.00138 NA
124 hsa-miR-361-5p C18orf25 -0.65 0 0.25 3.0E-5 mirMAP -0.16 2.0E-5 NA
125 hsa-miR-361-5p C2CD3 -0.65 0 -0.09 0.17034 miRanda -0.15 0.0001 NA
126 hsa-miR-361-5p C3orf58 -0.65 0 0.39 6.0E-5 PITA; miRNATAP -0.14 0.01574 NA
127 hsa-miR-361-5p C5orf51 -0.65 0 0.15 0.01292 miRNATAP -0.18 0 NA
128 hsa-miR-361-5p CA8 -0.65 0 0.62 0.0176 miRanda -0.76 0 NA
129 hsa-miR-361-5p CABYR -0.65 0 0.71 0 miRanda -0.25 0.00203 NA
130 hsa-miR-361-5p CACNB4 -0.65 0 0.97 0 miRanda; mirMAP -0.43 2.0E-5 NA
131 hsa-miR-361-5p CALCOCO2 -0.65 0 0.24 0 miRNAWalker2 validate; miRanda -0.13 0 NA
132 hsa-miR-361-5p CALCRL -0.65 0 0.44 0.00449 MirTarget; PITA; miRanda; miRNATAP -0.45 0 NA
133 hsa-miR-361-5p CALD1 -0.65 0 1.23 0 miRanda; miRNATAP -0.5 0 NA
134 hsa-miR-361-5p CALHM2 -0.65 0 0.63 0 miRanda -0.14 0.02702 NA
135 hsa-miR-361-5p CAMK2D -0.65 0 0.51 0 PITA; miRanda; miRNATAP -0.24 1.0E-5 NA
136 hsa-miR-361-5p CAPN6 -0.65 0 2.48 0 PITA; miRanda; miRNATAP -0.89 0 NA
137 hsa-miR-361-5p CASK -0.65 0 -0.03 0.61182 mirMAP -0.12 0.00015 NA
138 hsa-miR-361-5p CASP1 -0.65 0 0.94 0 miRanda -0.26 0.00441 NA
139 hsa-miR-361-5p CASP10 -0.65 0 0.41 0.00298 miRanda -0.23 0.00522 NA
140 hsa-miR-361-5p CASP2 -0.65 0 -0.07 0.53424 miRanda -0.36 0 NA
141 hsa-miR-361-5p CAT -0.65 0 0.52 0 miRanda -0.31 0 NA
142 hsa-miR-361-5p CAV1 -0.65 0 1.75 0 miRanda -0.49 0 NA
143 hsa-miR-361-5p CAV2 -0.65 0 1.54 0 miRanda -0.47 0 NA
144 hsa-miR-361-5p CBX5 -0.65 0 0.17 0.00637 mirMAP -0.2 0 NA
145 hsa-miR-361-5p CBX6 -0.65 0 0.85 0 mirMAP -0.53 0 NA
146 hsa-miR-361-5p CCDC121 -0.65 0 0.21 0.00438 miRanda -0.22 0 NA
147 hsa-miR-361-5p CCDC6 -0.65 0 -0.27 0.00044 miRanda -0.21 1.0E-5 NA
148 hsa-miR-361-5p CCDC68 -0.65 0 1.04 0 miRanda -0.35 0.00122 NA
149 hsa-miR-361-5p CCDC88A -0.65 0 1.01 0 miRanda -0.32 3.0E-5 NA
150 hsa-miR-361-5p CCDC91 -0.65 0 0.16 0.00908 miRanda -0.19 0 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 CELL DEVELOPMENT 153 1426 1.181e-12 1.832e-09
2 CARDIOVASCULAR SYSTEM DEVELOPMENT 100 788 1.089e-12 1.832e-09
3 CIRCULATORY SYSTEM DEVELOPMENT 100 788 1.089e-12 1.832e-09
4 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 87 689 4.524e-11 5.263e-08
5 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 162 1656 3.578e-10 2.618e-07
6 NEUROGENESIS 142 1402 5.065e-10 2.618e-07
7 VASCULATURE DEVELOPMENT 65 469 3.095e-10 2.618e-07
8 CELLULAR COMPONENT MORPHOGENESIS 102 900 4.943e-10 2.618e-07
9 TISSUE DEVELOPMENT 151 1518 4.829e-10 2.618e-07
10 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 87 724 5.756e-10 2.678e-07
11 BLOOD VESSEL MORPHOGENESIS 54 364 8.578e-10 3.326e-07
12 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 138 1360 8.109e-10 3.326e-07
13 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 161 1672 1.301e-09 4.658e-07
14 POSITIVE REGULATION OF MOLECULAR FUNCTION 169 1791 2.147e-09 7.135e-07
15 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 120 1152 2.493e-09 7.733e-07
16 NEURON PROJECTION DEVELOPMENT 69 545 4.373e-09 1.197e-06
17 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 138 1395 4.244e-09 1.197e-06
18 POSITIVE REGULATION OF GENE EXPRESSION 162 1733 9.427e-09 2.193e-06
19 LOCOMOTION 115 1114 9.176e-09 2.193e-06
20 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 64 498 8.956e-09 2.193e-06
21 CELL PROJECTION ORGANIZATION 98 902 9.93e-09 2.2e-06
22 PROTEIN LOCALIZATION 166 1805 1.885e-08 3.988e-06
23 POSITIVE REGULATION OF CELL COMMUNICATION 145 1532 2.906e-08 5.878e-06
24 POSITIVE REGULATION OF RESPONSE TO STIMULUS 174 1929 3.219e-08 5.945e-06
25 NEURON DIFFERENTIATION 94 874 3.295e-08 5.945e-06
26 NEGATIVE REGULATION OF CELL COMMUNICATION 119 1192 3.322e-08 5.945e-06
27 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 100 957 5.003e-08 8.314e-06
28 INTRACELLULAR SIGNAL TRANSDUCTION 147 1572 4.94e-08 8.314e-06
29 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 162 1784 6.709e-08 1.076e-05
30 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 124 1275 7.363e-08 1.142e-05
31 NEURON DEVELOPMENT 77 687 1.139e-07 1.71e-05
32 REGULATION OF CELL DIFFERENTIATION 139 1492 1.489e-07 2.166e-05
33 CELL PART MORPHOGENESIS 72 633 1.671e-07 2.25e-05
34 PEPTIDYL AMINO ACID MODIFICATION 89 841 1.607e-07 2.25e-05
35 ANGIOGENESIS 42 293 1.692e-07 2.25e-05
36 PROTEIN PHOSPHORYLATION 97 944 1.776e-07 2.296e-05
37 TUBE DEVELOPMENT 65 552 1.927e-07 2.423e-05
38 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 101 1004 2.712e-07 3.321e-05
39 HEART DEVELOPMENT 57 466 3.141e-07 3.747e-05
40 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 61 513 3.273e-07 3.807e-05
41 CHONDROCYTE DIFFERENTIATION 16 60 3.435e-07 3.899e-05
42 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 111 1142 3.863e-07 4.28e-05
43 POSITIVE REGULATION OF CATALYTIC ACTIVITY 139 1518 4.042e-07 4.374e-05
44 NEURON PROJECTION MORPHOGENESIS 51 402 4.32e-07 4.569e-05
45 TISSUE MORPHOGENESIS 62 533 5.639e-07 5.83e-05
46 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 100 1008 5.953e-07 6.021e-05
47 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 159 1805 6.111e-07 6.05e-05
48 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 162 1848 6.36e-07 6.165e-05
49 REGULATION OF PROTEIN MODIFICATION PROCESS 152 1710 6.58e-07 6.248e-05
50 REGULATION OF DEVELOPMENTAL GROWTH 40 289 8.334e-07 7.317e-05
51 CELL MOTILITY 86 835 8.24e-07 7.317e-05
52 LOCALIZATION OF CELL 86 835 8.24e-07 7.317e-05
53 HEAD DEVELOPMENT 76 709 8.065e-07 7.317e-05
54 MORPHOGENESIS OF AN EPITHELIUM 50 400 8.728e-07 7.521e-05
55 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 79 750 9.763e-07 8.26e-05
56 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 34 229 1.103e-06 8.848e-05
57 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 170 1977 1.095e-06 8.848e-05
58 RESPONSE TO OXYGEN CONTAINING COMPOUND 127 1381 1.076e-06 8.848e-05
59 REGULATION OF CELLULAR COMPONENT BIOGENESIS 80 767 1.228e-06 9.685e-05
60 REGULATION OF CELL PROJECTION ORGANIZATION 63 558 1.278e-06 9.913e-05
61 CENTRAL NERVOUS SYSTEM DEVELOPMENT 88 872 1.438e-06 0.0001097
62 REGULATION OF TRANSPORT 157 1804 1.493e-06 0.0001121
63 REGULATION OF CELL DEVELOPMENT 85 836 1.616e-06 0.0001193
64 REGULATION OF GTPASE ACTIVITY 72 673 1.692e-06 0.000123
65 RESPONSE TO WOUNDING 63 563 1.727e-06 0.0001237
66 RESPONSE TO ENDOGENOUS STIMULUS 131 1450 1.837e-06 0.0001295
67 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 99 1021 1.892e-06 0.0001314
68 UROGENITAL SYSTEM DEVELOPMENT 40 299 1.995e-06 0.0001365
69 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 26 156 2.286e-06 0.0001542
70 POSITIVE REGULATION OF GROWTH 34 238 2.675e-06 0.0001778
71 ESTABLISHMENT OF PROTEIN LOCALIZATION 128 1423 3.042e-06 0.0001994
72 POSITIVE REGULATION OF RESPONSE TO EXTRACELLULAR STIMULUS 13 48 3.568e-06 0.0002274
73 POSITIVE REGULATION OF RESPONSE TO NUTRIENT LEVELS 13 48 3.568e-06 0.0002274
74 REGULATION OF CELL DEATH 131 1472 3.99e-06 0.0002509
75 GROWTH 49 410 4.047e-06 0.0002511
76 REGULATION OF PHOSPHORUS METABOLIC PROCESS 141 1618 5.083e-06 0.0003112
77 TUBE MORPHOGENESIS 41 323 5.654e-06 0.0003417
78 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 48 406 6.8e-06 0.0004015
79 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 39 303 6.816e-06 0.0004015
80 REGULATION OF NEURON PROJECTION DEVELOPMENT 48 408 7.768e-06 0.0004518
81 CELLULAR RESPONSE TO NITROGEN COMPOUND 56 505 8.453e-06 0.0004856
82 PROTEIN CATABOLIC PROCESS 62 579 8.622e-06 0.0004893
83 CELLULAR RESPONSE TO STRESS 136 1565 8.757e-06 0.0004909
84 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 89 926 8.987e-06 0.0004978
85 WOUND HEALING 53 470 9.12e-06 0.0004993
86 REGULATION OF EPITHELIAL CELL PROLIFERATION 37 285 9.561e-06 0.0005173
87 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 79 799 1.059e-05 0.0005662
88 HOMEOSTATIC PROCESS 119 1337 1.135e-05 0.0006003
89 DEVELOPMENTAL GROWTH 41 333 1.193e-05 0.0006235
90 POSITIVE REGULATION OF AXONOGENESIS 15 69 1.244e-05 0.0006434
91 FOREBRAIN DEVELOPMENT 43 357 1.278e-05 0.0006533
92 ESTABLISHMENT OF LOCALIZATION IN CELL 143 1676 1.304e-05 0.0006598
93 RESPONSE TO NITROGEN COMPOUND 83 859 1.49e-05 0.0007455
94 REGULATION OF CELLULAR RESPONSE TO STRESS 70 691 1.528e-05 0.0007561
95 DENDRITE DEVELOPMENT 16 79 1.67e-05 0.0008096
96 REGULATION OF NEURON DIFFERENTIATION 59 554 1.668e-05 0.0008096
97 RESPONSE TO ABIOTIC STIMULUS 95 1024 1.863e-05 0.0008937
98 PHOSPHORYLATION 110 1228 1.887e-05 0.0008958
99 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 49 437 2.282e-05 0.001072
100 CARTILAGE DEVELOPMENT 23 147 2.483e-05 0.001144
101 REGULATION OF CELLULAR LOCALIZATION 113 1277 2.461e-05 0.001144
102 REGULATION OF AXONOGENESIS 25 168 2.701e-05 0.001232
103 REGULATION OF CELL MORPHOGENESIS 58 552 2.9e-05 0.00131
104 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 15 74 3.013e-05 0.001348
105 REGULATION OF COENZYME METABOLIC PROCESS 12 50 3.207e-05 0.001408
106 REGULATION OF COFACTOR METABOLIC PROCESS 12 50 3.207e-05 0.001408
107 EPITHELIUM DEVELOPMENT 88 945 3.314e-05 0.001433
108 POSITIVE REGULATION OF HYDROLASE ACTIVITY 85 905 3.326e-05 0.001433
109 REGULATION OF RESPONSE TO STRESS 126 1468 3.401e-05 0.001452
110 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 40 337 3.545e-05 0.001478
111 REGULATION OF BODY FLUID LEVELS 54 506 3.555e-05 0.001478
112 POSITIVE REGULATION OF AUTOPHAGY 15 75 3.558e-05 0.001478
113 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 18 102 3.652e-05 0.001504
114 CELL PROLIFERATION 67 672 3.816e-05 0.001557
115 REGULATION OF PROTEIN LOCALIZATION 88 950 4.017e-05 0.001625
116 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 41 352 4.399e-05 0.001756
117 CONNECTIVE TISSUE DEVELOPMENT 27 194 4.415e-05 0.001756
118 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 18 104 4.772e-05 0.001882
119 DEVELOPMENTAL CELL GROWTH 15 77 4.915e-05 0.001922
120 REGULATION OF CELLULAR COMPONENT MOVEMENT 74 771 5.371e-05 0.002083
121 ENDOMEMBRANE SYSTEM ORGANIZATION 50 465 5.647e-05 0.002171
122 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 42 368 5.722e-05 0.002182
123 RHYTHMIC PROCESS 36 298 5.933e-05 0.002244
124 CELL GROWTH 21 135 6.008e-05 0.002255
125 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 57 554 6.087e-05 0.002266
126 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 30 232 6.945e-05 0.002565
127 PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 81 873 7.693e-05 0.002818
128 INSULIN RECEPTOR SIGNALING PATHWAY 15 80 7.798e-05 0.002835
129 REGULATION OF HYDROLASE ACTIVITY 114 1327 7.899e-05 0.002849
130 PEPTIDYL SERINE MODIFICATION 22 148 8.16e-05 0.002921
131 REGULATION OF ORGANELLE ORGANIZATION 103 1178 9.063e-05 0.003219
132 PROTEOLYSIS 105 1208 9.736e-05 0.003432
133 REGULATION OF ORGAN GROWTH 14 73 0.0001039 0.003633
134 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 35 296 0.0001149 0.00399
135 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 19 121 0.0001166 0.00399
136 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 23 162 0.0001164 0.00399
137 REGULATION OF CELL PROLIFERATION 125 1496 0.0001184 0.004
138 SINGLE ORGANISM CELLULAR LOCALIZATION 82 898 0.0001186 0.004
139 REGULATION OF GROWTH 62 633 0.0001218 0.004076
140 REGULATION OF MAPK CASCADE 64 660 0.0001267 0.004212
141 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 88 983 0.0001339 0.004419
142 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 27 207 0.0001355 0.00444
143 POSITIVE REGULATION OF KINASE ACTIVITY 50 482 0.0001384 0.004473
144 POSITIVE REGULATION OF HEART GROWTH 8 27 0.0001375 0.004473
145 CELLULAR MACROMOLECULE LOCALIZATION 106 1234 0.0001421 0.004529
146 HEMOSTASIS 36 311 0.0001421 0.004529
147 REGULATION OF SYNAPSE ORGANIZATION 18 113 0.0001449 0.004587
148 REGULATION OF HOMEOSTATIC PROCESS 47 447 0.0001586 0.004985
149 MESENCHYMAL CELL DIFFERENTIATION 20 134 0.0001596 0.004985
150 VESICLE MEDIATED TRANSPORT 106 1239 0.0001657 0.005139
151 REGULATION OF EPITHELIAL CELL MIGRATION 23 166 0.0001687 0.0052
152 ORGAN MORPHOGENESIS 77 841 0.0001752 0.005327
153 POSITIVE REGULATION OF TRANSPORT 84 936 0.0001749 0.005327
154 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 18 115 0.000182 0.005442
155 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 46 437 0.0001807 0.005442
156 WNT SIGNALING PATHWAY 39 351 0.0001824 0.005442
157 RESPONSE TO GROWTH FACTOR 49 475 0.0001836 0.005442
158 CELLULAR RESPONSE TO INSULIN STIMULUS 21 146 0.0001883 0.005544
159 NEGATIVE REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 11 51 0.000191 0.005588
160 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 91 1036 0.0001994 0.005727
161 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 91 1036 0.0001994 0.005727
162 MACROMOLECULE CATABOLIC PROCESS 83 926 0.0001988 0.005727
163 CYTOSKELETON DEPENDENT INTRACELLULAR TRANSPORT 18 116 0.0002035 0.005808
164 MESENCHYME DEVELOPMENT 25 190 0.0002057 0.005837
165 ORGANELLE TRANSPORT ALONG MICROTUBULE 12 60 0.0002113 0.005926
166 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 98 1135 0.0002114 0.005926
167 POSITIVE REGULATION OF NEURON DIFFERENTIATION 35 306 0.0002202 0.006089
168 RESPONSE TO LIPID 80 888 0.0002202 0.006089
169 NLS BEARING PROTEIN IMPORT INTO NUCLEUS 7 22 0.0002211 0.006089
170 REGULATION OF INTRACELLULAR TRANSPORT 60 621 0.0002246 0.006148
171 REGULATION OF NEURON APOPTOTIC PROCESS 25 192 0.0002425 0.006597
172 REGULATION OF AUTOPHAGY 30 249 0.0002479 0.006697
173 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 16 98 0.000249 0.006697
174 REGULATION OF CATABOLIC PROCESS 68 731 0.0002651 0.007089
175 CELLULAR RESPONSE TO PEPTIDE 32 274 0.0002769 0.007363
176 EXOCRINE SYSTEM DEVELOPMENT 10 45 0.0002867 0.007537
177 TELENCEPHALON DEVELOPMENT 28 228 0.0002866 0.007537
178 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 73 801 0.0002939 0.007682
179 REGULATION OF ANATOMICAL STRUCTURE SIZE 48 472 0.0002958 0.00769
180 CELL CYCLE 110 1316 0.0003029 0.007831
181 MEMBRANE BIOGENESIS 8 30 0.0003081 0.007921
182 REGULATION OF CELLULAR COMPONENT SIZE 37 337 0.0003333 0.008505
183 POSITIVE REGULATION OF NUCLEOTIDE CATABOLIC PROCESS 6 17 0.0003345 0.008505
184 PROTEIN LOCALIZATION TO VACUOLE 10 46 0.0003467 0.008721
185 POSITIVE REGULATION OF ORGAN GROWTH 9 38 0.0003459 0.008721
186 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 53 541 0.0003675 0.009031
187 HOMEOSTASIS OF NUMBER OF CELLS 23 175 0.0003688 0.009031
188 REGULATION OF CYTOSKELETON ORGANIZATION 50 502 0.0003642 0.009031
189 PEPTIDYL TYROSINE MODIFICATION 24 186 0.0003662 0.009031
190 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 53 541 0.0003675 0.009031
191 RESPONSE TO ORGANIC CYCLIC COMPOUND 81 917 0.0003732 0.009092
192 PROTEIN LOCALIZATION TO ORGANELLE 54 556 0.0004007 0.009711
193 INTERSPECIES INTERACTION BETWEEN ORGANISMS 62 662 0.0004086 0.009801
194 SYMBIOSIS ENCOMPASSING MUTUALISM THROUGH PARASITISM 62 662 0.0004086 0.009801
195 CYTOSKELETON ORGANIZATION 75 838 0.0004171 0.009953
NumGOOverlapSizeP ValueAdj. P Value
1 ENZYME BINDING 172 1737 3.495e-11 3.247e-08
2 CHROMATIN BINDING 57 435 2.952e-08 1.371e-05
3 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 45 328 2.257e-07 6.191e-05
4 MACROMOLECULAR COMPLEX BINDING 131 1399 2.666e-07 6.191e-05
5 RIBONUCLEOTIDE BINDING 162 1860 9.455e-07 0.0001464
6 PROTEIN DOMAIN SPECIFIC BINDING 69 624 8.586e-07 0.0001464
7 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 42 315 1.218e-06 0.0001517
8 PHOSPHATASE BINDING 27 162 1.47e-06 0.0001517
9 TRANSCRIPTION FACTOR BINDING 60 524 1.444e-06 0.0001517
10 PROTEIN KINASE ACTIVITY 69 640 2.124e-06 0.0001973
11 PROTEIN PHOSPHATASE BINDING 22 120 2.711e-06 0.0002289
12 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 32 226 6.296e-06 0.0004874
13 KINASE BINDING 64 606 9.654e-06 0.0006899
14 REGULATORY REGION NUCLEIC ACID BINDING 80 818 1.382e-05 0.0009173
15 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 65 629 1.649e-05 0.001021
16 PHOSPHATIDYLINOSITOL PHOSPHATE BINDING 20 116 1.962e-05 0.001072
17 MOLECULAR FUNCTION REGULATOR 119 1353 1.95e-05 0.001072
18 KINASE ACTIVITY 81 842 2.21e-05 0.00114
19 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 92 992 2.563e-05 0.001253
20 PHOSPHATIDYLINOSITOL BINDING 28 200 2.883e-05 0.001339
21 LIPID BINDING 66 657 3.455e-05 0.001459
22 PHOSPHOLIPID BINDING 42 360 3.435e-05 0.001459
23 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 37 303 3.738e-05 0.001479
24 ADENYL NUCLEOTIDE BINDING 129 1514 3.821e-05 0.001479
25 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 106 1199 4.602e-05 0.00171
26 CORE PROMOTER PROXIMAL REGION DNA BINDING 42 371 6.889e-05 0.002461
27 ENZYME ACTIVATOR ACTIVITY 50 471 7.812e-05 0.002688
28 NUCLEOSIDE TRIPHOSPHATASE REGULATOR ACTIVITY 38 329 9.853e-05 0.00322
29 IDENTICAL PROTEIN BINDING 105 1209 0.0001005 0.00322
30 DOUBLE STRANDED DNA BINDING 72 764 0.0001191 0.003689
31 UBIQUITIN LIKE PROTEIN TRANSFERASE ACTIVITY 45 420 0.0001415 0.004144
32 PROTEIN SERINE THREONINE KINASE ACTIVITY 47 445 0.0001427 0.004144
33 SH3 DOMAIN BINDING 18 116 0.0002035 0.005727
34 RECEPTOR BINDING 122 1476 0.0002233 0.006101
35 PROTEIN TRANSPORTER ACTIVITY 16 99 0.0002806 0.007448
36 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 14 81 0.0003262 0.00819
37 SEQUENCE SPECIFIC DNA BINDING 90 1037 0.0003225 0.00819
38 CORE PROMOTER SEQUENCE SPECIFIC DNA BINDING 16 101 0.0003544 0.008663
NumGOOverlapSizeP ValueAdj. P Value
1 CELL PROJECTION 171 1786 5.641e-10 3.294e-07
2 CELL JUNCTION 121 1151 1.224e-09 3.574e-07
3 NEURON PROJECTION 101 942 1.158e-08 2.254e-06
4 NEURON PART 124 1265 4.734e-08 6.912e-06
5 SYNAPSE 83 754 7.969e-08 9.308e-06
6 VACUOLE 116 1180 1.145e-07 1.114e-05
7 CELL SUBSTRATE JUNCTION 51 398 3.171e-07 2.177e-05
8 CELL PROJECTION PART 96 946 3.657e-07 2.177e-05
9 GOLGI APPARATUS 134 1445 3.317e-07 2.177e-05
10 SYNAPSE PART 69 610 3.728e-07 2.177e-05
11 MEMBRANE REGION 110 1134 4.831e-07 2.565e-05
12 DENDRITE 55 451 5.562e-07 2.707e-05
13 POSTSYNAPSE 48 378 9.138e-07 4.105e-05
14 ENDOSOME 81 793 2.39e-06 9.968e-05
15 NEURON SPINE 22 121 3.127e-06 0.0001171
16 ANCHORING JUNCTION 56 489 3.208e-06 0.0001171
17 SOMATODENDRITIC COMPARTMENT 69 650 3.649e-06 0.0001254
18 VACUOLAR MEMBRANE 63 587 6.792e-06 0.0002204
19 CELL LEADING EDGE 43 350 7.784e-06 0.0002392
20 PERINUCLEAR REGION OF CYTOPLASM 67 642 8.884e-06 0.0002594
21 VACUOLAR PART 71 694 9.532e-06 0.0002651
22 FILOPODIUM 18 94 1.149e-05 0.0002916
23 CYTOPLASMIC REGION 37 287 1.121e-05 0.0002916
24 INTRACELLULAR VESICLE 113 1259 1.324e-05 0.0003221
25 CELL CELL JUNCTION 45 383 1.53e-05 0.0003574
26 PLASMA MEMBRANE REGION 88 929 1.757e-05 0.0003947
27 MEMBRANE MICRODOMAIN 36 288 2.877e-05 0.0006222
28 SITE OF POLARIZED GROWTH 23 149 3.096e-05 0.0006458
29 EARLY ENDOSOME MEMBRANE 19 113 4.497e-05 0.0009057
30 NUCLEAR ENVELOPE 46 416 5.652e-05 0.0011
31 MICROTUBULE CYTOSKELETON 95 1068 9.186e-05 0.001692
32 ACTIN BASED CELL PROJECTION 25 181 9.444e-05 0.001692
33 ENDOPLASMIC RETICULUM 135 1631 9.561e-05 0.001692
34 CYTOSKELETON 158 1967 0.0001061 0.001822
35 AXON 44 418 0.0002472 0.004125
36 CELL CORTEX 29 238 0.0002576 0.004179
37 LAMELLIPODIUM 23 172 0.0002865 0.004521
38 ORGANELLE SUBCOMPARTMENT 35 311 0.0003001 0.004612
39 TRANSFERASE COMPLEX 65 703 0.0004231 0.006336
40 ENDOSOMAL PART 44 430 0.0004552 0.006646
41 CELL SURFACE 68 757 0.0006923 0.009862

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Ras_signaling_pathway_hsa04014 33 232 4.105e-06 0.0002135
2 Regulation_of_actin_cytoskeleton_hsa04810 30 208 8.378e-06 0.0002178
3 Adherens_junction_hsa04520 15 72 2.139e-05 0.0003707
4 MAPK_signaling_pathway_hsa04010 36 295 4.799e-05 0.0006238
5 Mitophagy_animal_hsa04137 13 65 0.0001164 0.001211
6 Sphingolipid_signaling_pathway_hsa04071 18 118 0.0002531 0.002194
7 FoxO_signaling_pathway_hsa04068 19 132 0.00037 0.002547
8 Endocytosis_hsa04144 29 244 0.0003918 0.002547
9 Focal_adhesion_hsa04510 24 199 0.0009742 0.005629
10 Rap1_signaling_pathway_hsa04015 24 206 0.001572 0.008085
11 ErbB_signaling_pathway_hsa04012 13 85 0.00171 0.008085
12 Phosphatidylinositol_signaling_system_hsa04070 14 99 0.002477 0.01073
13 cGMP_PKG_signaling_pathway_hsa04022 19 163 0.004569 0.01784
14 PI3K_Akt_signaling_pathway_hsa04151 34 352 0.004804 0.01784
15 cAMP_signaling_pathway_hsa04024 21 198 0.008756 0.03035
16 Autophagy_animal_hsa04140 15 128 0.01046 0.03399
17 TNF_signaling_pathway_hsa04668 13 108 0.01334 0.04081
18 Phospholipase_D_signaling_pathway_hsa04072 16 146 0.01533 0.04429
19 Gap_junction_hsa04540 11 88 0.01683 0.04524
20 HIF_1_signaling_pathway_hsa04066 12 100 0.0174 0.04524
21 Hippo_signaling_pathway_hsa04390 16 154 0.02416 0.05888
22 VEGF_signaling_pathway_hsa04370 8 59 0.02491 0.05888
23 TGF_beta_signaling_pathway_hsa04350 10 84 0.02984 0.06711
24 Wnt_signaling_pathway_hsa04310 15 146 0.03097 0.06711
25 Apoptosis_hsa04210 14 138 0.03972 0.08262
26 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 14 139 0.04182 0.08363
27 p53_signaling_pathway_hsa04115 8 68 0.05192 0.09748
28 Tight_junction_hsa04530 16 170 0.05249 0.09748
29 ECM_receptor_interaction_hsa04512 9 82 0.05893 0.1048
30 AMPK_signaling_pathway_hsa04152 12 121 0.06217 0.1048
31 Hedgehog_signaling_pathway_hsa04340 6 47 0.06246 0.1048
32 Apelin_signaling_pathway_hsa04371 13 137 0.07128 0.1101
33 Cell_cycle_hsa04110 12 124 0.07202 0.1101
34 Oocyte_meiosis_hsa04114 12 124 0.07202 0.1101
35 Hippo_signaling_pathway_multiple_species_hsa04392 4 29 0.09497 0.1411
36 mTOR_signaling_pathway_hsa04150 13 151 0.1261 0.1821
37 Necroptosis_hsa04217 13 164 0.1934 0.2717
38 Calcium_signaling_pathway_hsa04020 14 182 0.2121 0.2903
39 Cellular_senescence_hsa04218 12 160 0.2613 0.3485
40 Jak_STAT_signaling_pathway_hsa04630 12 162 0.2751 0.3576
41 Autophagy_other_hsa04136 3 32 0.3049 0.3867
42 Lysosome_hsa04142 9 123 0.3264 0.399
43 Notch_signaling_pathway_hsa04330 4 48 0.3299 0.399
44 NF_kappa_B_signaling_pathway_hsa04064 7 95 0.351 0.4148
45 Peroxisome_hsa04146 6 83 0.3871 0.4473
46 Phagosome_hsa04145 10 152 0.4382 0.4851
47 Ferroptosis_hsa04216 3 40 0.4385 0.4851
48 ABC_transporters_hsa02010 3 45 0.517 0.5601
49 Cytokine_cytokine_receptor_interaction_hsa04060 16 270 0.5697 0.6046
50 Apoptosis_multiple_species_hsa04215 2 33 0.6012 0.6253
51 Cell_adhesion_molecules_.CAMs._hsa04514 8 145 0.6555 0.6683
52 Neuroactive_ligand_receptor_interaction_hsa04080 15 278 0.7122 0.7122

Quest ID: ed70fe6d86b426eb3a394265297163f3