Publication

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S. S. Li, Carman K.M. Ip, Matthew Y.H. Tang, Maggie K.S. Tang, Y Tong, Zhang J, A. A. Hassan, Abby S.C. Mak, S. Yung, T. M. Chan, Philip P. Ip, C. Lee, Philip C.N. Chiu, L. T. Lee, H. C. Lai, J. Z. Zeng, Ho Cheung Shum, Alice S.T. Wong . Sialyl Lewis x-P-selectin cascade mediates tumor–mesothelial adhesion in ascitic fluid shear flow. Nature communications, 10(1), 1-11

Lai K.P., Wang Y, Li J,W,, Tong Y, Chan T.F., Jin N, Tse A, Zhang J, Wan M.T., Tam N and Au D.W.T., Lee BY, Lee J S, Wong A S, Kong R Y, Wu Rudolf S S. 2019. Hypoxia causes transgenerational impairment of ovarian development and hatching success in fish. Environmental science & technology.

Ru B, Wong CN, Tong Y, Zhong JY, Zhong SSW, Wu WC, Chu KC, Wong CY, Lau CY, Chen I, Chan NW, Zhang J. (2019) TISIDB: an integrated repository portal for tumor-immune system interactions. Bioinformatics. btz210. SJR: 0.62%

Huang K, Ru B, Zhang Y, Chan WL, Chow SC, Zhang J, Lo C, Lui WY. (2019) Sertoli cell-specific coxsackievirus and adenovirus receptor knockout regulates cell adhesion and gene transcription via β-catenin inactivation and Cdc42 activation. The FASEB Journal. 33(6):7588-602.

Yan HHN, Siu HC, Law S, Ho SL, Yue SSK, Tsui WY, Chan D, Chan AS, Ma S, Lam KO, Bartfeld S, Man AHY, Lee BCH, Chan ASY, Wong JWH, Cheng PSW, Chan AKW, Zhang J, Shi J, Fan X, Kwong DLW, Mak TW, Yuen ST, Clevers H, Leung SY. (2018) A comprehensive human gastric cancer organoid biobank captures tumor subtype heterogeneity and enables therapeutic screening. Cell Stem Cell. 23(6):882-897.e11. SJR: 0.13%

Ru B*, Sun J*, Kang Q, Tong Y, Zhang J. (2018) A framework for identifying dysregulated chromatin regulators as master regulators in human cancer. Bioinformatics. bty836. (*co-first author) SJR: 0.62%

Chen M, Zhang J, Berger AH, Diolombi MS, Ng C, Fung J, Bronson RT, Castillo-Martin M, Thin TH, Cordon-Cardo C, Plevin R, Pandolfi PP. (2018) Compound haploinsufficiency of DOK2 and DUSP4 cooperates to promote lung tumorigenesis. Journal of Clinical Investigation. 129, no. 1: 215-222.SJR 0.39%

Padmanabhan A, Tong Y, Wu Q, Zhang J, Shah NP. (2018) Transcriptomic insights into the growth phase-and sugar-associated changes in the exopolysaccharide production mechanism of a high EPS-producing Streptococcus thermophilus ASCC 1275. Frontiers in Microbiology. 9:1919.

Ru B, Tong Y, Zhang J. (2018) MR4Cancer: a web server prioritizing master regulators for cancer. Bioinformatics. bty658. SJR: 0.62%

Tong Y*, Sun J*, Wong CF, Kang Q, Ru B, Wong CN, Chan AS, Leung SY, Zhang J. (2018) MICMIC: identification of DNA methylation of distal regulatory regions with causal effects on tumorigenesis. Genome Biology. 19:73. (*co-first author) SJR: 0.15%

Tong Y, Ru B, Zhang J. (2018) miRNACancerMAP: an integrative web server inferring miRNA regulation network for cancer. Bioinformatics. bty320. SJR: 0.62%

Ru B, Sun J, Tong Y, Wong CN, Chandra A, Tang ATS, Chow LKY, Wun WL, Levitskaya Z, Zhang J. (2018) CR2Cancer: a database for chromatin regulators in human cancer. Nucleic Acids Research. 46(D1):D918-D924. SJR: 0.28%

Chen M, Zhang J, Sampieri K, Clohessy JG, Mendez L, Gonzalez-Billalabeitia E, Liu XS, Lee YR, Fung J, Katon JM, Menon AV, Webster KA, Ng C, Palumbieri MD, Diolombi MS, Breitkopf SB, Teruya-Feldstein J, Signoretti S, Bronson RT, Asara JM, Castillo-Martin M, Cordon-Cardo C, Pandolfi PP. (2018) An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer. Nature Genetics. 50:206-18. Impact factor: 28.0 Citation Index: 4

Bezzi M, Seitzer N, Ishikawa T, Reschke M, Chen M, Wang G, Mitchell C, Ng C, Katon J, Lunardi A, Signoretti S, Clohessy JG, Zhang J, Pandolfi PP. (2018) Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms. Nature Medicine. 24:165-75. Impact factor: 30.0 Citation Index: 5

Chen M, Wan L, Zhang J, Zhang J, Mendez L, Clohessy J, Berry K, Victor J, Yin Q, Yuan Z, Wei W, Pandolfi PP. (2018) Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism. Nature Communications. 9:159. Impact factor: 12.1 Citation Index: 1

To SKY, Mak ASC, Fung YME, Che CM, Li SS, Deng W, Ru B, Zhang J, Wong AST. (2017) β-catenin downregulates Dicer to promote ovarian cancer metastasis. Oncogene. 36(43):5927-38. Impact factor: 7.5 Citation Index: 2

Zhao Y, Fan D, Ru B, Cheng KW, Hu S, Zhang J, Li ETS, Wang M. (2016) 6-C-(E-phenylethenyl) naringenin induces cell growth inhibition and cytoprotective autophagy in colon cancer cells. European Journal of Cancer. 68:38-50. Impact factor: 6.2 Citation Index: 6

Wang SY, Lau K, Lai KP, Zhang J, Tse AC, Li JW, Tong Y, Chan TF, Wong CK, Chiu JM, Au DW, Wong AS, Kong RY, Wu RS (2016) Hypoxia causes transgenerational impairments in reproduction of fish. Nature Communications. 7: 12114. Impact factor: 11.3 Citation Index: 2

Bao X, Wang Y, Li X, Li XM, Liu Z, Yang T, Wong CF, Zhang J, Hao Q, Li XD. (2014) Identification of 'erasers' for lysine crotonylated histone marks using a chemical proteomics approach. Elife. 2014 Nov 4;3. doi: 10.7554/eLife.02999. Impact factor: 8.3 Citation Index: 35

Toso A, Revandkar A, Di Mitri D, Guccini I, Proietti M, Sarti M, Pinton S, Zhang J, Kalathur M, Civenni G, Jarrossay D, Montani E, Marini C, Garcia-Escudero R, Scanziani E, Grassi F, Pandolfi PP, Catapano CV, Alimonti A. Enhancing chemotherapy efficacy in Pten-deficient prostate tumors by activating the senescence-associated antitumor immunity. (2014) Cell Rep 9(1):75-89. Epub 2014 Sep 25. Impact factor: 7.9 Citation Index: 37

Shen Y, Zhang J, Calarco JA, Zhang Y. (2014) EOL-1, The Homolog of the Mammalian Dom3Z, Regulates Olfactory Learning in C. elegans. J Neurosci. 34(40):13364-70. Impact factor: 5.5 Citation Index: 1

Picard M, Zhang J, Hanecock S, Derbeneva O, Golhar R, Golik P, O'Hearn S, Levy SE, Potluri P, Lvova M, Davila A, Lin CS, Perin JC, Rappaport EF, Hakonarson H, Trounce I, Procaccio V, Wallace DC. (2014) Progressive increase in mtDNA 3243A>G heteroplasmy results in abrupt transcriptional remodeling. Proc Natl Acad Sci U S A. 111(38):E4033-42. Impact factor: 9.4 Citation Index: 38

Seijffers R, Zhang J, Matthews JC, Chen A, Tamrazian E, Babaniyi O, Selig M, Hynynen M, Woolf CJ, Brown RH Jr. ATF3 expression improves motor function in the ALS mouse model by promoting motor neuron survival and retaining muscle innervation. Proc Natl Acad Sci U S A. 111(4):1622-7. Epub 2014 Jan 13. Impact factor: 9.4 Citation Index: 9

Kats LM, Reschke M, Taulli R, Pozdnyakova O, Burgess K, Bhargava P, Straley K, Karnik R, Meissner A, Small D, Su SM, Yen K, Zhang J, Pandolfi PP (2014) Proto-Oncogenic Role of Mutant IDH2 in Leukemia Initiation and Maintenance. Cell Stem Cell. 14(3):329-41 Impact factor:22.4 Citation Index: 43

Dose M, Emmanuel AO, Chaumeil J, Zhang J, Sun T, Germar K, Aghajani K, Davis EM, Keerthivasan S, Bredemeyer AL, Sleckman BP, Rosen ST, Skok JA, Le Beau MM, Georgopoulos K, Gounari F. β-Catenin induces T-cell transformation by promoting genomic instability (2014) Proc Natl Acad Sci U S A. 111(1):391-6. Impact factor:9.4 Citation Index: 17

Joshi I, Yoshida T, Jena N, Qi X, Zhang J, Van Etten RA, Georgopoulos K (2014) Ikaros Mutation Confers Integrin-Dependent Survival Of Pre-B Cells and Progression To Acute Lymphoblastic Leukemia. Nat Immunol. 15(3):294-304. Impact factor: 19.4 Citation Index: 32

Yoshida T, Landhuis E, Dose M, Hazan I, Zhang J, Naito T, Jackson AF, Wu J, Perroti EA, Kaufmann C, Gounari F, Morgan BA, Georgopoulos K (2013) Transcriptional regulation of the Ikzf1 locus. Blood. 122(18):3149-59. Impact factor: 11.8 Citation Index: 7

So MY, Tian ZP, Phoon YS, Sha S, Antoniou MN, Zhang J, Wu RSS, Tan-Un KC. (2014) Gene Expression Profile And Toxic Effects In Human Bronchial Epithelial Cells Exposed To Zearalenone. PLoS One 2014 2;9(5):e96404. Epub 2014 May 2.

Zhang M, Song F, Liang L, Nan H, Zhang J, Liu H, Wang LE, Wei Q, Lee JE, Amos CI, Kraft P, Qureshi AA, Han J. (2013) Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans. Hum Mol Genet. 22(14):2948-59 Impact factor: 6.0 Citation Index: 22

Wang G, Lunardi A, Zhang J, Chen Z, Ala U, Webster KA, Tay Y, Gonzalez-Billalabeitia E, Egia A, Shaffer DR, Carver B, Liu XS, Taulli R, Kuo WP, Nardella C, Signoretti S, Cordon-Cardo C, Gerald WL, Pandolfi PP (2013) Zbtb7a suppresses prostate cancer through repression of a Sox 9-dependent pathway for cellular senescence bypass and tumor invasion. Nat Genet. 45(7):739-46. Impact factor: 32 Citation Index: 36

Shoag J, Haq R, Zhang M, Liu L, Rowe GC, Jiang A, Koulisis N, Farrel C, Amos CI, Wei Q, Lee JE, Zhang J, Kupper TS, Qureshi AA, Cui R, Han J, Fisher DE, Arany Z. (2013) PGC-1 coactivators regulate MITF and the tanning response. Mol Cell. 49(1):145-57. Impact factor: 14 Citation Index: 20

Zhang J*, Jackson Af*, Naito T*, Liu F, Dosei M, Seavitt J, Liu F, Dose M, Kashiwagi M, Yoshida T, Gounari F, Petrie H, Georgopoulos K. (2012) Harnessing of the Nucleosome Remodeling Deacetylase complex controls lymphocyte development and prevents leukemogenesis. Nature Immunology 13, 86-94 - Highlighted in Nature Immunology 13, 16᾿8 (*co-first author). Impact factor: 19.4 Citation Index: 78

Gregg C*, Zhang J*, Weissbourd B, Luo S, Schroth G, Haig D, and Dulac C. (2010) High-resolution analysis of parent-of-origin allelic expression in the mouse brain. Science 6;329(5992):643-48 (*co-first author) - Impact factor:35 Citation Index: 297

Gregg C, Zhang J, Luo S, Schroth G, Haig D, and Dulac C. (2010) Sex-Specific Genomic Imprinting in the Mouse Brain. Science 6;329(5992):682-85 Impact factor:35 Citation Index: 184

Zhao M, Zhang J, Phatnani H, Scheu S, Maniatis T. (2012) Stochastic Expression of the Interferon-β Gene. PLoS Biol. 10(1). Impact factor:8.7 Citation Index: 40

El-Haibi CP, Bell GW, Zhang J, Collmann AY, Wood D, Scherber CM, Csizmadia E, Mariani O, Zhu C, Campagne A, Toner M, Bhatia SN, Irimia D, Vincent-Salomon A, Karnoub AE. (2012) Critical role for lysyl oxidase in mesenchymal-stem-cell-driven breast cancer malignancy. Proc Natl Acad Sci U S A. 109(43):17460-5 Impact factor: 9.4 Citation Index: 62

Bonneaud C, Balenger S, Zhang J, Edwards SV, Hill GE. (2012) Innate immunity and the evolution of resistance to an emerging infectious disease in a wild bird. Molecular Ecology 21, 2628᾿639. Impact factor:5.9 Citation Index: 21

Han J, Qureshi AA, Nan H, Zhang J, Song Y, Guo Q, Hunter DJ. (2011) A Germline Variant in the Interferon Regulatory Factor 4 Gene as a Novel Skin Cancer Risk Locus. Cancer Res. 71(5):1533-9. Impact factor: 9.3 Citation Index: 19

Bonneaud C, Balenger S, Russell AF, Zhang J, Hill GE, Edwards SV. (2011) Rapid evolution of disease resistance is accompanied by functional changes in gene expression in a wild bird. Proc Natl Acad Sci U S A. 108(19):7866-71. Impact factor: 9.4 Citation Index: 43

Germar K, Dose M, Konstantinou T, Zhang J, Wang H, Lobry C, Arnett K, Blacklow S, Aifantis I, Aster J, Gounari F. (2011) Tcf-1 is a gatekeeper for T-cell specification in response to Notch signaling. Proc Natl Acad Sci U S A. 108(50):20060-5. Impact factor:9.4 Citation Index: 61

Nan H, Xu M, Zhang J, Zhang M, Kraft P, Qureshi A, Chen C, Guo Q, Hu FB, Rimm EB, Curhan G, Song Y, Amos CI, Wang L, Lee JE, Wei Q, Hunter DJ, Han J. (2011) Genome-wide association study identifies nidogen 1 (NID1) as a susceptibility locus to cutaneous nevi and melanoma risk. Hum Mol Genet. 20(13):2673-9. Impact factor: 6.0 Citation Index: 26

Finley L, Carracedo A, Souza A, Haas W, Egia A, Zhang J, Teruya-Feldstein J, Clish CB, Procaccio V, Pandolfi PP, Haigis MC. (2011) SIRT3 opposes reprogramming of cancer cell metabolism through HIF1alpha destabilization. Cancer Cell 19(3):416-28 Impact factor:23.5 Citation Index: 263

Poliseno L, Salmena L, Zhang J, Carver B, Haveman WJ, and Pandolfi PP (2010). A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature 24;465(7301):1033-8. Impact factor: 38 Citation Index: 774

Alimonti A, Carracedo A, Clohessy JG, Trotman LC, Nardella C, Egia A, Salmena L, Sampieri K, Haveman WJ, Brogi E, Richardson AL, Zhang J, and Pandolfi PP (2010). Subtle variations in Pten dose determine cancer susceptibility. Nat Genet. 42(5):454-8 Impact factor: 32 Citation Index: 230

Gómez-del Arco P, Kashiwagi M, Jackson AF, Naito T, Zhang J, Liu F, Kee B, Vooijs M, Radtke F, Redondo JM, Georgopoulos K (2010). Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis. Immunity 33(5):685-98. Impact factor: 24.1 Citation Index: 39

Ng SY*, Yoshida T*, Zhang J*, Georgopoulos K. (2009) Genome-wide Lineage-Specific Transcriptional Networks Underscore Ikaros-Dependent Lymphoid Priming in Hematopoietic Stem Cells Immunity. Immunity 30(4):493-507 (*co-first author) Impact factor: 24.1 Citation Index: 120

Yoshida T, Zhang J, Hazan I, Naito T, Ng SY, Snippert HJ, Heller EJ, Lawton L, Williams CJ, and Georgopoulos K. (2008). The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation. Genes Dev. 22, 1174-1189. Impact factor: 10.0 Citation Index: 85

Makeyev EV, Zhang J, Carrasco MA, and Maniatis, T. (2007). The MicroRNA miR-124 promotes neuronal differentiation by triggering brainspecific alternative pre-mRNA splicing. Mol. Cell 27, 435-448. Impact factor: 14.0 Citation Index: 653

Lesic B, Lépine F, Déziel E, Zhang J, Zhang Q, Padfield K, Castonguay MH, Milot S, Stachel S, Tzika AA, Tompkins RG, Rahme LG. (2007) Inhibitors of pathogen intercellular signals as selective anti-infective compounds. PLoS Pathog. 3(9):1229-39. Impact factor: 7.0 Citation Index: 92

Tzika AA, Mintzopoulos D, Mindrinos M, Zhang J, Rahme LG, and Tompkins RG. (2009). Microarray analysis suggests that burn injury results in mitochondrial dysfunction in human skeletal muscle. Int J Mol Med. 24(3):387-92. Impact factor: 2.1 Citation Index: 17

Tzika AA, Mintzopoulos D, Padfield K, Wilhelmy J, Mindrinos MN, Yu H, Cao H, Zhang Q, Astrakas LG, Zhang J, Yu YM, Rahme LG, Tompkins RG. (2008) Reduced rate of adenosine triphosphate synthesis by in vivo 31P nuclear magnetic resonance spectroscopy and downregulation of PGC-1beta in distal skeletal muscle following burn. Int J Mol Med. 2008 Feb;21(2):201-8. Impact factor: 2.1 Citation Index: 12

Tzika AA, Astrakas L, Cao H, Mintzopoulos D, Andronesi OC, Mindrinos M, Zhang J, Rahme LG, Blekas KD, Likas AC, Galatsanos NP, Carroll RS, Black PM. (2007) Combination of high-resolution magic angle spinning proton magnetic resonance spectroscopy and microscale genomics to type brain tumor biopsies. Int J Mol Med. 20(2):199-208.Impact factor: 2.1 Citation Index: 38

Santos D, Ho AW, Tournilhac O, Hatjiharissi E, Leleu X, Xu L, Tassone P, Neri P, Hunter ZR, Chemaly MA, Branagan AR, Manning RJ, Patterson CJ, Moreau AS, Ciccarelli B, Adamia S, Kriangkum J, Kutok JL, Tai YT, Zhang J, Pilarski LM, Anderson KC, Munshi N, Treon SP. (2007) Establishment of BCWM.1 cell line for Waldenström's macroglobulinemia with productive in vivo engraftment in SCID-hu mice. Exp Hematol. 35(9):1366-75. Impact factor: 2.5 Citation Index: 28

Zhang J, Tang QQ, Vinson C, and Lane MD. (2004) Dominant negative C/EBP blocks mitotic clonal expansion of adipocytes. Proc Natl Acad Sci USA 101(1):43-7. Impact factor: 9.4 Citation Index: 168

Zhang J, Klemm D, Vinson C, and Lane MD. (2004) Role of CREB in transcriptional regulation of CCAAT/enhancer-binding protein beta gene during adipogenesis. Journal of Biological Chemistry. 279(6):4471-8. Impact factor: 4.57 Citation Index: 215

Tang QQ, Zhang J, and Lane MD. (2004) Sequential gene promoter interactions of C/EBPbeta, C/EBPalpha, and PPARgamma during adipogenesis. Biochemical and Biophysical Research Communications 319(1):235-9 Impact factor: 2.3 Citation Index: 51