Browse ACTA1 in pancancer

Summary
SymbolACTA1
Nameactin, alpha 1, skeletal muscle
Aliases NEM3; nemaline myopathy type 3; ACTA; ASMA; CFTD1; Alpha-actin-1; Actin, alpha skeletal muscle
Location1q42.13
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Domain, Function and Classification
> Gene Ontology
> KEGG and Reactome Pathway
> Domain, Function and Classification
 
Domain PF00022 Actin
Function

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

Classification
Class Modification Substrate Product PubMed
# # # # #
> Gene Ontology
 
Biological Process GO:0003012 muscle system process
GO:0006936 muscle contraction
GO:0007015 actin filament organization
GO:0007517 muscle organ development
GO:0007519 skeletal muscle tissue development
GO:0009612 response to mechanical stimulus
GO:0009991 response to extracellular stimulus
GO:0010035 response to inorganic substance
GO:0010038 response to metal ion
GO:0010226 response to lithium ion
GO:0010927 cellular component assembly involved in morphogenesis
GO:0014706 striated muscle tissue development
GO:0014866 skeletal myofibril assembly
GO:0014888 striated muscle adaptation
GO:0014902 myotube differentiation
GO:0014904 myotube cell development
GO:0016049 cell growth
GO:0030048 actin filament-based movement
GO:0030049 muscle filament sliding
GO:0030239 myofibril assembly
GO:0030240 skeletal muscle thin filament assembly
GO:0031032 actomyosin structure organization
GO:0033275 actin-myosin filament sliding
GO:0042692 muscle cell differentiation
GO:0043500 muscle adaptation
GO:0043501 skeletal muscle adaptation
GO:0043503 skeletal muscle fiber adaptation
GO:0048545 response to steroid hormone
GO:0048741 skeletal muscle fiber development
GO:0048747 muscle fiber development
GO:0051146 striated muscle cell differentiation
GO:0055001 muscle cell development
GO:0055002 striated muscle cell development
GO:0060485 mesenchyme development
GO:0060537 muscle tissue development
GO:0060538 skeletal muscle organ development
GO:0070252 actin-mediated cell contraction
GO:0072132 mesenchyme morphogenesis
GO:0090130 tissue migration
GO:0090131 mesenchyme migration
Molecular Function GO:0005200 structural constituent of cytoskeleton
GO:0017022 myosin binding
GO:0043531 ADP binding
Cellular Component GO:0001725 stress fiber
GO:0005865 striated muscle thin filament
GO:0005884 actin filament
GO:0015629 actin cytoskeleton
GO:0030016 myofibril
GO:0030017 sarcomere
GO:0030027 lamellipodium
GO:0030175 filopodium
GO:0031252 cell leading edge
GO:0032432 actin filament bundle
GO:0036379 myofilament
GO:0042641 actomyosin
GO:0043292 contractile fiber
GO:0044297 cell body
GO:0044449 contractile fiber part
GO:0072562 blood microparticle
GO:0097517 contractile actin filament bundle
GO:0098858 actin-based cell projection
> KEGG and Reactome Pathway
 
KEGG -
Reactome -
Summary
SymbolACTA1
Nameactin, alpha 1, skeletal muscle
Aliases NEM3; nemaline myopathy type 3; ACTA; ASMA; CFTD1; Alpha-actin-1; Actin, alpha skeletal muscle
Location1q42.13
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Mutation landscape in primary tumor tissue from TCGA
> Mutation landscape in cancer cell line from CCLE
> All mutations from COSMIC database V81
> Variations from text mining
> The Cancer Genome Atlas (TCGA)
 
> Cancer Cell Line Encyclopedia (CCLE)
 
There is no record.
> Catalogue of Somatic Mutations in Cancer (COSMIC)
 
COSMIC ID CDS change AA change Mutation Type Anatomical Site
COSM1997433c.886T>Cp.Y296HSubstitution - MissenseLarge_intestine
COSM5458362c.586A>Gp.T196ASubstitution - MissenseLarge_intestine
COSM5990958c.116G>Ap.R39HSubstitution - MissenseProstate
COSM1601864c.406G>Ap.V136MSubstitution - MissenseLiver
COSM1339922c.25G>Ap.A9TSubstitution - MissenseLarge_intestine
COSM3789613c.707C>Ap.S236YSubstitution - MissenseUrinary_tract
COSM1243063c.1034G>Ap.G345DSubstitution - MissenseOesophagus
COSM5666318c.771C>Ap.F257LSubstitution - MissenseSoft_tissue
COSM905243c.306G>Ap.E102ESubstitution - coding silentEndometrium
COSM1339910c.911delGp.G304fs*24Deletion - FrameshiftLarge_intestine
COSM393967c.1109C>Ap.S370YSubstitution - MissenseLung
COSM1339919c.267C>Ap.H89QSubstitution - MissenseLarge_intestine
COSM1339914c.726C>Tp.Y242YSubstitution - coding silentOesophagus
COSM5620198c.1099G>Tp.A367SSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM905242c.492C>Tp.N164NSubstitution - coding silentEndometrium
COSM4538305c.252G>Ap.M84ISubstitution - MissenseSkin
COSM1600146c.353G>Ap.R118HSubstitution - MissenseCentral_nervous_system
COSM1317565c.762C>Tp.N254NSubstitution - coding silentStomach
COSM5810192c.928G>Tp.G310WSubstitution - MissenseLiver
COSM4957300c.429C>Tp.S143SSubstitution - coding silentLiver
COSM1339916c.435C>Tp.Y145YSubstitution - coding silentLarge_intestine
COSM1997429c.998C>Ap.A333DSubstitution - MissenseLarge_intestine
COSM4416627c.130-10G>Cp.?UnknownHaematopoietic_and_lymphoid_tissue
COSM1320408c.148G>Tp.G50CSubstitution - MissenseOvary
COSM1339918c.331C>Ap.P111TSubstitution - MissenseLarge_intestine
COSM4957300c.429C>Tp.S143SSubstitution - coding silentLiver
COSM1473574c.1006G>Ap.E336KSubstitution - MissenseBreast
COSM1317565c.762C>Tp.N254NSubstitution - coding silentHaematopoietic_and_lymphoid_tissue
COSM4563005c.952G>Ap.E318KSubstitution - MissenseSkin
COSM905240c.592C>Tp.R198CSubstitution - MissenseStomach
COSM3369597c.225C>Tp.H75HSubstitution - coding silentThyroid
COSM318487c.1103G>Cp.G368ASubstitution - MissenseLung
COSM3385880c.7G>Ap.D3NSubstitution - MissensePancreas
COSM3930675c.821C>Gp.A274GSubstitution - MissenseUrinary_tract
COSM383002c.367C>Ap.Q123KSubstitution - MissenseLung
COSM905241c.564C>Ap.T188TSubstitution - coding silentEndometrium
COSM4515111c.999C>Tp.A333ASubstitution - coding silentSkin
COSM5053182c.1010G>Ap.R337HSubstitution - MissenseStomach
COSM5053183c.438C>Ap.A146ASubstitution - coding silentStomach
COSM3864721c.446G>Ap.R149KSubstitution - MissenseSkin
COSM905240c.592C>Tp.R198CSubstitution - MissenseLarge_intestine
COSM905238c.988A>Gp.K330ESubstitution - MissenseEndometrium
COSM3804266c.897C>Tp.N299NSubstitution - coding silentBreast
COSM679183c.69C>Tp.F23FSubstitution - coding silentBreast
COSM679185c.90G>Tp.R30SSubstitution - MissenseLung
COSM1997433c.886T>Cp.Y296HSubstitution - MissenseLarge_intestine
COSM1339912c.868G>Ap.D290NSubstitution - MissenseLarge_intestine
COSM5924169c.990G>Ap.K330KSubstitution - coding silentSkin
COSM5817841c.1055C>Tp.S352FSubstitution - MissenseLiver
COSM5679954c.704C>Ap.S235YSubstitution - MissenseSoft_tissue
COSM3369596c.1049C>Gp.S350WSubstitution - MissenseThyroid
COSM5808901c.499A>Gp.I167VSubstitution - MissenseLiver
COSM1339916c.435C>Tp.Y145YSubstitution - coding silentStomach
COSM3356534c.661G>Ap.V221MSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM679192c.933C>Tp.I311ISubstitution - coding silentLung
COSM3385879c.814G>Ap.E272KSubstitution - MissensePancreas
COSM4659086c.757G>Ap.G253SSubstitution - MissenseLarge_intestine
COSM1339914c.726C>Tp.Y242YSubstitution - coding silentLarge_intestine
COSM268568c.92C>Tp.A31VSubstitution - MissenseLarge_intestine
COSM905240c.592C>Tp.R198CSubstitution - MissenseOesophagus
COSM5626552c.756C>Tp.I252ISubstitution - coding silentOesophagus
COSM3804267c.522G>Ap.P174PSubstitution - coding silentBreast
COSM1339915c.681C>Tp.N227NSubstitution - coding silentLarge_intestine
COSM4622581c.623G>Ap.R208HSubstitution - MissenseLarge_intestine
COSM905244c.243G>Ap.W81*Substitution - NonsenseEndometrium
COSM5675902c.1101C>Tp.A367ASubstitution - coding silentSoft_tissue
COSM3984816c.550G>Ap.G184SSubstitution - MissenseKidney
COSM905239c.962C>Tp.A321VSubstitution - MissenseEndometrium
COSM1601863c.468C>Gp.D156ESubstitution - MissenseLiver
COSM271085c.65G>Ap.G22DSubstitution - MissenseLarge_intestine
COSM3484907c.582C>Tp.I194ISubstitution - coding silentSkin
COSM5010751c.991-1G>Tp.?UnknownKidney
COSM4659087c.690G>Ap.A230ASubstitution - coding silentLarge_intestine
COSM3977173c.64G>Ap.G22SSubstitution - MissenseLung
COSM1601863c.468C>Gp.D156ESubstitution - MissenseLiver
COSM5832509c.659_660delACp.Y220fs*68Deletion - FrameshiftBreast
COSM3789614c.642C>Gp.I214MSubstitution - MissenseUrinary_tract
COSM1339915c.681C>Tp.N227NSubstitution - coding silentLarge_intestine
COSM3484906c.1037C>Tp.S346FSubstitution - MissenseSkin
COSM5832510c.655_656delTGp.C219fs*69Deletion - FrameshiftBreast
COSM4029316c.454G>Ap.G152SSubstitution - MissenseStomach
COSM1997429c.998C>Ap.A333DSubstitution - MissenseLarge_intestine
COSM3369597c.225C>Tp.H75HSubstitution - coding silentLarge_intestine
COSM5521031c.634C>Ap.R212SSubstitution - MissenseBiliary_tract
COSM3484909c.57G>Ap.V19VSubstitution - coding silentSkin
COSM425545c.762C>Ap.N254KSubstitution - MissenseBreast
COSM4609869c.71C>Tp.A24VSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM905245c.15C>Tp.D5DSubstitution - coding silentEndometrium
COSM1238126c.665C>Tp.A222VSubstitution - MissenseOesophagus
COSM905237c.1001C>Tp.P334LSubstitution - MissenseEndometrium
COSM4459500c.1128C>Tp.C376CSubstitution - coding silentSkin
COSM4509446c.807C>Ap.I269ISubstitution - coding silentSkin
COSM1997452c.171C>Tp.G57GSubstitution - coding silentStomach
COSM4659085c.1032C>Tp.G344GSubstitution - coding silentLarge_intestine
COSM1997439c.638A>Gp.D213GSubstitution - MissenseLarge_intestine
COSM679183c.69C>Tp.F23FSubstitution - coding silentLung
COSM4893215c.289C>Tp.R97CSubstitution - MissenseSkin
COSM4029315c.477C>Tp.D159DSubstitution - coding silentStomach
COSM679183c.69C>Tp.F23FSubstitution - coding silentOesophagus
COSM679182c.63C>Gp.A21ASubstitution - coding silentLung
COSM3735806c.55G>Ap.V19MSubstitution - MissenseSkin
COSM679189c.414C>Tp.I138ISubstitution - coding silentLung
COSM1601864c.406G>Ap.V136MSubstitution - MissenseLiver
COSM1339920c.82G>Ap.A28TSubstitution - MissenseLarge_intestine
COSM1339916c.435C>Tp.Y145YSubstitution - coding silentLarge_intestine
COSM679188c.306G>Tp.E102DSubstitution - MissenseLung
COSM5009446c.543C>Tp.D181DSubstitution - coding silentLarge_intestine
COSM679187c.181C>Tp.Q61*Substitution - NonsenseLung
COSM370691c.309C>Ap.H103QSubstitution - MissenseLung
COSM414578c.541G>Ap.D181NSubstitution - MissenseUrinary_tract
COSM4416669c.130-5T>Cp.?UnknownHaematopoietic_and_lymphoid_tissue
COSM3484908c.341C>Tp.P114LSubstitution - MissenseSkin
COSM1745342c.709_711delTCCp.S237delSDeletion - In frameUrinary_tract
COSM1668543c.766C>Tp.R256CSubstitution - MissenseLarge_intestine
COSM905240c.592C>Tp.R198CSubstitution - MissenseEndometrium
COSM1339917c.401T>Cp.M134TSubstitution - MissenseLarge_intestine
COSM5040129c.367C>Tp.Q123*Substitution - NonsenseLiver
COSM1339915c.681C>Tp.N227NSubstitution - coding silentLarge_intestine
COSM3730437c.963G>Ap.A321ASubstitution - coding silentStomach
COSM337650c.74G>Tp.G25VSubstitution - MissenseLung
COSM1668543c.766C>Tp.R256CSubstitution - MissenseLarge_intestine
COSM4029313c.738C>Tp.D246DSubstitution - coding silentStomach
COSM1339913c.808G>Ap.G270SSubstitution - MissenseLarge_intestine
COSM679183c.69C>Tp.F23FSubstitution - coding silentCervix
COSM905242c.492C>Tp.N164NSubstitution - coding silentStomach
COSM679183c.69C>Tp.F23FSubstitution - coding silentOesophagus
COSM1181711c.941G>Ap.R314HSubstitution - MissenseLarge_intestine
COSM3377022c.906G>Ap.S302SSubstitution - coding silentPancreas
COSM673780c.656G>Ap.C219YSubstitution - MissenseEndometrium
COSM5781374c.697G>Tp.A233SSubstitution - MissenseBreast
COSM5916969c.253G>Ap.E85KSubstitution - MissenseSkin
COSM1997445c.475G>Ap.D159NSubstitution - MissensePeritoneum
COSM242792c.885G>Tp.L295LSubstitution - coding silentProstate
COSM346578c.823G>Tp.G275CSubstitution - MissenseLung
COSM5900977c.319C>Tp.L107FSubstitution - MissenseSkin
COSM4659088c.248A>Gp.D83GSubstitution - MissenseLarge_intestine
COSM4029314c.631G>Ap.V211MSubstitution - MissenseStomach
COSM679191c.819G>Tp.S273SSubstitution - coding silentLung
COSM1339911c.911G>Ap.G304DSubstitution - MissenseLarge_intestine
COSM679190c.429C>Gp.S143SSubstitution - coding silentLung
COSM1339921c.48C>Tp.S16SSubstitution - coding silentLarge_intestine
COSM905246c.6C>Tp.C2CSubstitution - coding silentEndometrium
COSM4546838c.408G>Ap.V136VSubstitution - coding silentSkin
COSM5832511c.648delGp.K217fs*69Deletion - FrameshiftBreast
COSM5651999c.1099_1123del25p.A367fs*>3Deletion - FrameshiftHaematopoietic_and_lymphoid_tissue
COSM4542801c.325G>Ap.E109KSubstitution - MissenseSkin
> Text Mining based Variations
 
There is no record for ACTA1.
Summary
SymbolACTA1
Nameactin, alpha 1, skeletal muscle
Aliases NEM3; nemaline myopathy type 3; ACTA; ASMA; CFTD1; Alpha-actin-1; Actin, alpha skeletal muscle
Location1q42.13
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Post-translational modification (PTM)
> Post-translational modification (PTM)
 
 Filter By:
Uniprot ID Position Amino Acid Description Upstream Enzyme Affected By Mutation Amino Acid Sequence Variant
P6813346MMethionine (R)-sulfoxide-NoNone detected
P6813349MMethionine (R)-sulfoxide-NoNone detected
P6813363KN6-malonyllysine-NoNone detected
P6813386KN6-methyllysine-NoNone detected
Summary
SymbolACTA1
Nameactin, alpha 1, skeletal muscle
Aliases NEM3; nemaline myopathy type 3; ACTA; ASMA; CFTD1; Alpha-actin-1; Actin, alpha skeletal muscle
Location1q42.13
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Expression analysis in primary tumor tissue from TCGA
> Expression level in cancer cell line from CCLE
> Expression level in human normal tissue from HPA
> Text mining based expression change
> The Cancer Genome Atlas (TCGA)
 


  Differential expression analysis for cancers with more than 10 normal samples
Cancer Full Name # N # T Median (N) Median (T) LogFC Adj. P Status
BLCABladder urothelial carcinoma19408-1.34-2.411-1.8651.5e-05Under
BRCABreast invasive carcinoma1121100-1.876-0.8360.8990.000787Over
GBMGlioblastoma multiforme51660.737-2.181NANANA
HNSCHead and Neck squamous cell carcinoma445228.130.068-4.4252.11e-08Under
LGGBrain Lower Grade Glioma0530NA-1.598NANANA
LUADLung adenocarcinoma59517-1.418-2.358-0.6630.00466Under
OVOvarian serous cystadenocarcinoma0307NA-3.448NANANA
PCPGPheochromocytoma and Paraganglioma3184-3.0990.577NANANA
PRADProstate adenocarcinoma524982.348-0.35-2.4024.07e-08Under
SARCSarcoma2263-0.09-1.682NANANA
SKCMSkin Cutaneous Melanoma1472-2.747-2.506NANANA
STADStomach adenocarcinoma35415-2.287-3.54-0.90.0231Under
TGCTTesticular Germ Cell Tumors0156NA-0.174NANANA
THYMThymoma2120-0.145-2.472NANANA
UCECUterine Corpus Endometrial Carcinoma35546-2.237-1.9040.1970.499NS
> Cancer Cell Line Encyclopedia (CCLE)
 



Tissue Cell Line Expression Level (Microarray)
Autonomic ganglia CHP126 4
Autonomic ganglia CHP212 3.9
Autonomic ganglia IMR32 4.4
Autonomic ganglia KELLY 3.9
Autonomic ganglia KPNRTBM1 4.1
Autonomic ganglia KPNSI9S 4
Autonomic ganglia KPNYN 3.7
Autonomic ganglia MHHNB11 4.3
Autonomic ganglia NB1 4.1
Autonomic ganglia NH6 4
Autonomic ganglia SHSY5Y 3.7
Autonomic ganglia SIMA 4
Autonomic ganglia SKNAS 3.9
Autonomic ganglia SKNBE2 4.1
Autonomic ganglia SKNDZ 4.1
Autonomic ganglia SKNFI 3.6
Autonomic ganglia SKNSH 4
Biliary tract HUCCT1 3.9
Biliary tract HUH28 4.3
Biliary tract SNU1079 3.9
Biliary tract SNU1196 4.1
Biliary tract SNU245 4
Biliary tract SNU308 4
Biliary tract SNU478 4.1
Bone 143B 4.1
Bone A673 4
Bone CADOES1 3.9
Bone CAL78 4
Bone G292CLONEA141B1 3.9
Bone HOS 4.1
Bone HS706T 4
Bone HS737T 4.2
Bone HS819T 4.3
Bone HS821T 4.4
Bone HS822T 4.4
Bone HS863T 4.1
Bone HS870T 3.8
Bone HS888T 3.8
Bone MG63 4.4
Bone MHHES1 3.9
Bone OUMS27 4
Bone RDES 3.9
Bone SJSA1 4
Bone SKES1 3.8
Bone SKNMC 3.8
Bone SW1353 4.2
Bone T173 3.8
Bone TC71 4.1
Bone U2OS 4.1
Breast AU565 4.5
Breast BT20 3.8
Breast BT474 4.2
Breast BT483 4
Breast BT549 3.8
Breast CAL120 4.3
Breast CAL148 3.9
Breast CAL51 4.1
Breast CAL851 4.9
Breast CAMA1 4.4
Breast DU4475 4.6
Breast EFM192A 9.9
Breast EFM19 6.1
Breast EVSAT 4
Breast HCC1143 4
Breast HCC1187 4.1
Breast HCC1395 3.9
Breast HCC1419 4.1
Breast HCC1428 4.3
Breast HCC1500 4
Breast HCC1569 3.9
Breast HCC1599 4
Breast HCC1806 4.3
Breast HCC1937 3.8
Breast HCC1954 4
Breast HCC202 4.8
Breast HCC2157 4.3
Breast HCC2218 4.4
Breast HCC38 11.7
Breast HCC70 4
Breast HDQP1 4
Breast HMC18 4.6
Breast HS274T 4
Breast HS281T 3.9
Breast HS343T 4
Breast HS578T 4.3
Breast HS606T 4.2
Breast HS739T 4.2
Breast HS742T 4.2
Breast JIMT1 4
Breast KPL1 4.1
Breast MCF7 3.9
Breast MDAMB134VI 3.9
Breast MDAMB157 4.2
Breast MDAMB175VII 4.1
Breast MDAMB231 3.9
Breast MDAMB361 4.3
Breast MDAMB415 4.8
Breast MDAMB436 4.2
Breast MDAMB453 4
Breast MDAMB468 4.4
Breast SKBR3 5.7
Breast T47D 3.9
Breast UACC812 4.3
Breast UACC893 5.2
Breast YMB1 4
Breast ZR751 4.2
Breast ZR7530 4.7
Central nervous system 1321N1 4.1
Central nervous system 42MGBA 3.8
Central nervous system 8MGBA 3.9
Central nervous system A172 4.1
Central nervous system AM38 3.9
Central nervous system BECKER 4
Central nervous system CAS1 4.1
Central nervous system CCFSTTG1 7
Central nervous system D283MED 4.2
Central nervous system D341MED 4.4
Central nervous system DAOY 3.9
Central nervous system DBTRG05MG 3.8
Central nervous system DKMG 4.1
Central nervous system GAMG 3.8
Central nervous system GB1 4.3
Central nervous system GI1 4
Central nervous system GMS10 7
Central nervous system GOS3 3.9
Central nervous system H4 3.8
Central nervous system HS683 3.8
Central nervous system KALS1 4.3
Central nervous system KG1C 3.6
Central nervous system KNS42 4.1
Central nervous system KNS60 3.8
Central nervous system KNS81 4.1
Central nervous system KS1 4.2
Central nervous system LN18 4
Central nervous system LN229 3.9
Central nervous system M059K 4.3
Central nervous system MOGGCCM 4.5
Central nervous system MOGGUVW 4
Central nervous system NMCG1 4.4
Central nervous system ONS76 4.1
Central nervous system SF126 3.9
Central nervous system SF295 3.8
Central nervous system SNB19 3.8
Central nervous system SNU1105 3.6
Central nervous system SNU201 4.3
Central nervous system SNU466 4.3
Central nervous system SNU489 4.1
Central nervous system SNU626 3.8
Central nervous system SNU738 4.2
Central nervous system SW1088 4
Central nervous system SW1783 4
Central nervous system T98G 3.8
Central nervous system TM31 3.8
Central nervous system U118MG 3.8
Central nervous system U138MG 3.9
Central nervous system U251MG 3.9
Central nervous system U87MG 3.9
Central nervous system YH13 3.9
Central nervous system YKG1 3.6
Endometrium AN3CA 4.3
Endometrium COLO684 5.2
Endometrium EFE184 4
Endometrium EN 4.1
Endometrium ESS1 3.8
Endometrium HEC108 4.4
Endometrium HEC151 3.9
Endometrium HEC1A 3.8
Endometrium HEC1B 4.2
Endometrium HEC251 4.4
Endometrium HEC265 4.2
Endometrium HEC50B 4.2
Endometrium HEC59 4
Endometrium HEC6 4.2
Endometrium ISHIKAWAHERAKLIO02ER 4.3
Endometrium JHUEM1 4.3
Endometrium JHUEM2 4.2
Endometrium JHUEM3 3.8
Endometrium KLE 5.8
Endometrium MFE280 4.2
Endometrium MFE296 4.5
Endometrium MFE319 3.9
Endometrium RL952 3.9
Endometrium SNGM 4.1
Endometrium SNU1077 4.4
Endometrium SNU685 4.6
Endometrium TEN 3.9
Haematopoietic and lymphoid 697 4.4
Haematopoietic and lymphoid A3KAW 4.1
Haematopoietic and lymphoid A4FUK 4
Haematopoietic and lymphoid ALLSIL 4.3
Haematopoietic and lymphoid AML193 4.2
Haematopoietic and lymphoid AMO1 4.2
Haematopoietic and lymphoid BCP1 4.4
Haematopoietic and lymphoid BDCM 4.1
Haematopoietic and lymphoid BL41 4.4
Haematopoietic and lymphoid BL70 4.1
Haematopoietic and lymphoid BV173 4
Haematopoietic and lymphoid CA46 4.2
Haematopoietic and lymphoid CI1 4.9
Haematopoietic and lymphoid CMK115 4.4
Haematopoietic and lymphoid CMK86 4.1
Haematopoietic and lymphoid CMK 3.9
Haematopoietic and lymphoid CMLT1 3.8
Haematopoietic and lymphoid COLO775 5.1
Haematopoietic and lymphoid DAUDI 4.4
Haematopoietic and lymphoid DB 3.9
Haematopoietic and lymphoid DEL 4.1
Haematopoietic and lymphoid DND41 4.4
Haematopoietic and lymphoid DOHH2 4.8
Haematopoietic and lymphoid EB1 4
Haematopoietic and lymphoid EB2 4.1
Haematopoietic and lymphoid EHEB 4.1
Haematopoietic and lymphoid EJM 4.2
Haematopoietic and lymphoid EM2 4.1
Haematopoietic and lymphoid EOL1 3.9
Haematopoietic and lymphoid F36P 4.1
Haematopoietic and lymphoid GA10 4.2
Haematopoietic and lymphoid GDM1 3.9
Haematopoietic and lymphoid GRANTA519 4
Haematopoietic and lymphoid HDLM2 4
Haematopoietic and lymphoid HDMYZ 3.9
Haematopoietic and lymphoid HEL9217 3.9
Haematopoietic and lymphoid HEL 3.8
Haematopoietic and lymphoid HH 4.5
Haematopoietic and lymphoid HL60 4.5
Haematopoietic and lymphoid HPBALL 4.1
Haematopoietic and lymphoid HS604T 4.3
Haematopoietic and lymphoid HS611T 4.6
Haematopoietic and lymphoid HS616T 3.9
Haematopoietic and lymphoid HS751T 4
Haematopoietic and lymphoid HT 4
Haematopoietic and lymphoid HTK 4
Haematopoietic and lymphoid HUNS1 4.1
Haematopoietic and lymphoid HUT102 4.2
Haematopoietic and lymphoid HUT78 4.2
Haematopoietic and lymphoid JEKO1 4.5
Haematopoietic and lymphoid JK1 4.2
Haematopoietic and lymphoid JM1 4.1
Haematopoietic and lymphoid JURKAT 3.7
Haematopoietic and lymphoid JURLMK1 4.1
Haematopoietic and lymphoid JVM2 4
Haematopoietic and lymphoid JVM3 4.4
Haematopoietic and lymphoid K562 4.1
Haematopoietic and lymphoid KARPAS299 4
Haematopoietic and lymphoid KARPAS422 4
Haematopoietic and lymphoid KARPAS620 4.1
Haematopoietic and lymphoid KASUMI1 4.3
Haematopoietic and lymphoid KASUMI2 4.4
Haematopoietic and lymphoid KASUMI6 4
Haematopoietic and lymphoid KCL22 4.1
Haematopoietic and lymphoid KE37 4.7
Haematopoietic and lymphoid KE97 4.2
Haematopoietic and lymphoid KG1 4.1
Haematopoietic and lymphoid KHM1B 4.4
Haematopoietic and lymphoid KIJK 4.2
Haematopoietic and lymphoid KMH2 4.2
Haematopoietic and lymphoid KMM1 4.5
Haematopoietic and lymphoid KMS11 4.2
Haematopoietic and lymphoid KMS12BM 4.1
Haematopoietic and lymphoid KMS18 4.2
Haematopoietic and lymphoid KMS20 4
Haematopoietic and lymphoid KMS21BM 4.7
Haematopoietic and lymphoid KMS26 3.9
Haematopoietic and lymphoid KMS27 4.3
Haematopoietic and lymphoid KMS28BM 4.1
Haematopoietic and lymphoid KMS34 4.1
Haematopoietic and lymphoid KO52 4.2
Haematopoietic and lymphoid KOPN8 4.3
Haematopoietic and lymphoid KU812 4.1
Haematopoietic and lymphoid KYO1 4.3
Haematopoietic and lymphoid L1236 4.3
Haematopoietic and lymphoid L363 5.5
Haematopoietic and lymphoid L428 4.6
Haematopoietic and lymphoid L540 3.9
Haematopoietic and lymphoid LAMA84 4.2
Haematopoietic and lymphoid LOUCY 4.4
Haematopoietic and lymphoid LP1 4
Haematopoietic and lymphoid M07E 4
Haematopoietic and lymphoid MC116 4.1
Haematopoietic and lymphoid ME1 4.3
Haematopoietic and lymphoid MEC1 4.1
Haematopoietic and lymphoid MEC2 4.5
Haematopoietic and lymphoid MEG01 3.8
Haematopoietic and lymphoid MHHCALL2 4.5
Haematopoietic and lymphoid MHHCALL3 4.3
Haematopoietic and lymphoid MHHCALL4 4
Haematopoietic and lymphoid MINO 4.2
Haematopoietic and lymphoid MJ 4.2
Haematopoietic and lymphoid MM1S 4.3
Haematopoietic and lymphoid MOLM13 4
Haematopoietic and lymphoid MOLM16 4.2
Haematopoietic and lymphoid MOLM6 4.2
Haematopoietic and lymphoid MOLP2 3.9
Haematopoietic and lymphoid MOLP8 4
Haematopoietic and lymphoid MOLT13 4.2
Haematopoietic and lymphoid MOLT16 3.9
Haematopoietic and lymphoid MOLT4 4.2
Haematopoietic and lymphoid MONOMAC1 4.3
Haematopoietic and lymphoid MONOMAC6 3.8
Haematopoietic and lymphoid MOTN1 4.3
Haematopoietic and lymphoid MUTZ5 4.2
Haematopoietic and lymphoid MV411 4.1
Haematopoietic and lymphoid NALM19 4.6
Haematopoietic and lymphoid NALM1 3.9
Haematopoietic and lymphoid NALM6 4.3
Haematopoietic and lymphoid NAMALWA 4
Haematopoietic and lymphoid NB4 4.2
Haematopoietic and lymphoid NCIH929 4.8
Haematopoietic and lymphoid NCO2 3.9
Haematopoietic and lymphoid NOMO1 4
Haematopoietic and lymphoid NUDHL1 4.5
Haematopoietic and lymphoid NUDUL1 4.5
Haematopoietic and lymphoid OCIAML2 4.1
Haematopoietic and lymphoid OCIAML3 3.9
Haematopoietic and lymphoid OCIAML5 4.3
Haematopoietic and lymphoid OCILY10 4.1
Haematopoietic and lymphoid OCILY19 4.4
Haematopoietic and lymphoid OCILY3 4.4
Haematopoietic and lymphoid OCIM1 4.1
Haematopoietic and lymphoid OPM2 4.3
Haematopoietic and lymphoid P12ICHIKAWA 4.1
Haematopoietic and lymphoid P31FUJ 4
Haematopoietic and lymphoid P3HR1 4.1
Haematopoietic and lymphoid PCM6 4.2
Haematopoietic and lymphoid PEER 4.7
Haematopoietic and lymphoid PF382 4.1
Haematopoietic and lymphoid PFEIFFER 4.1
Haematopoietic and lymphoid PL21 4.2
Haematopoietic and lymphoid RAJI 4.7
Haematopoietic and lymphoid RCHACV 4.2
Haematopoietic and lymphoid REC1 4.1
Haematopoietic and lymphoid REH 4.4
Haematopoietic and lymphoid RI1 4
Haematopoietic and lymphoid RL 3.9
Haematopoietic and lymphoid RPMI8226 4
Haematopoietic and lymphoid RPMI8402 4.1
Haematopoietic and lymphoid RS411 4.3
Haematopoietic and lymphoid SEM 4
Haematopoietic and lymphoid SET2 3.6
Haematopoietic and lymphoid SIGM5 4.7
Haematopoietic and lymphoid SKM1 4
Haematopoietic and lymphoid SKMM2 4
Haematopoietic and lymphoid SR786 4
Haematopoietic and lymphoid ST486 3.9
Haematopoietic and lymphoid SUDHL10 4.5
Haematopoietic and lymphoid SUDHL1 4
Haematopoietic and lymphoid SUDHL4 4.4
Haematopoietic and lymphoid SUDHL5 4.1
Haematopoietic and lymphoid SUDHL6 4.2
Haematopoietic and lymphoid SUDHL8 4
Haematopoietic and lymphoid SUPB15 4.3
Haematopoietic and lymphoid SUPHD1 4.2
Haematopoietic and lymphoid SUPM2 4.1
Haematopoietic and lymphoid SUPT11 4.2
Haematopoietic and lymphoid SUPT1 3.8
Haematopoietic and lymphoid TALL1 4.3
Haematopoietic and lymphoid TF1 4.5
Haematopoietic and lymphoid THP1 4.1
Haematopoietic and lymphoid TO175T 4.4
Haematopoietic and lymphoid TOLEDO 4.3
Haematopoietic and lymphoid U266B1 4.4
Haematopoietic and lymphoid U937 4
Haematopoietic and lymphoid UT7 4.1
Haematopoietic and lymphoid WSUDLCL2 4.2
Kidney 769P 4.2
Kidney 786O 4.1
Kidney A498 4.2
Kidney A704 3.8
Kidney ACHN 4.3
Kidney BFTC909 3.9
Kidney CAKI1 4.1
Kidney CAKI2 3.9
Kidney CAL54 4
Kidney KMRC1 4
Kidney KMRC20 4
Kidney KMRC2 4.4
Kidney KMRC3 4
Kidney OSRC2 4.2
Kidney RCC10RGB 4.2
Kidney SNU1272 4.1
Kidney SNU349 4.8
Kidney TUHR10TKB 4.1
Kidney TUHR14TKB 3.8
Kidney TUHR4TKB 4
Kidney VMRCRCW 3.9
Kidney VMRCRCZ 4
Large intestine C2BBE1 3.9
Large intestine CCK81 4.4
Large intestine CL11 4.2
Large intestine CL14 4.2
Large intestine CL34 4.1
Large intestine CL40 4.1
Large intestine COLO205 3.9
Large intestine COLO320 3.9
Large intestine COLO678 3.8
Large intestine CW2 4.1
Large intestine DLD1 4
Large intestine GP2D 3.8
Large intestine HCC56 4
Large intestine HCT116 4.4
Large intestine HCT15 4.1
Large intestine HS675T 4.1
Large intestine HS698T 4.2
Large intestine HT115 4.2
Large intestine HT29 4.1
Large intestine HT55 3.9
Large intestine KM12 4
Large intestine LOVO 4.3
Large intestine LS1034 4.2
Large intestine LS123 4.1
Large intestine LS180 4
Large intestine LS411N 4
Large intestine LS513 3.9
Large intestine MDST8 4.1
Large intestine NCIH508 4.3
Large intestine NCIH716 3.8
Large intestine NCIH747 4.1
Large intestine OUMS23 5
Large intestine RCM1 3.9
Large intestine RKO 4.1
Large intestine SKCO1 3.9
Large intestine SNU1040 3.8
Large intestine SNU1197 4.2
Large intestine SNU175 4
Large intestine SNU283 4.2
Large intestine SNU407 4
Large intestine SNU503 3.8
Large intestine SNU61 4.3
Large intestine SNU81 3.9
Large intestine SNUC1 3.8
Large intestine SNUC2A 4
Large intestine SNUC4 3.9
Large intestine SNUC5 4.2
Large intestine SW1116 4.2
Large intestine SW1417 4
Large intestine SW1463 3.9
Large intestine SW403 4.2
Large intestine SW480 4
Large intestine SW48 4.1
Large intestine SW620 4.1
Large intestine SW837 4
Large intestine SW948 4
Large intestine T84 4.2
Liver ALEXANDERCELLS 4.1
Liver C3A 8.8
Liver HEP3B217 4.3
Liver HEPG2 8
Liver HLE 3.7
Liver HLF 4.3
Liver HUH1 4
Liver HUH6 4
Liver HUH7 6.7
Liver JHH1 4.3
Liver JHH2 3.8
Liver JHH4 4.6
Liver JHH5 4.2
Liver JHH6 3.7
Liver JHH7 4.2
Liver LI7 3.9
Liver PLCPRF5 4.3
Liver SKHEP1 3.9
Liver SNU182 4
Liver SNU387 4
Liver SNU398 4
Liver SNU423 3.8
Liver SNU449 3.9
Liver SNU475 4.3
Liver SNU761 4.1
Liver SNU878 3.8
Liver SNU886 4.3
Lung A549 3.9
Lung ABC1 4.2
Lung BEN 4
Lung CAL12T 3.9
Lung CALU1 3.9
Lung CALU3 4.3
Lung CALU6 3.9
Lung CHAGOK1 3.8
Lung COLO668 3.7
Lung COLO699 3.7
Lung CORL105 4.3
Lung CORL23 4.3
Lung CORL24 3.8
Lung CORL279 4.4
Lung CORL311 4.2
Lung CORL47 3.7
Lung CORL51 4
Lung CORL88 4.2
Lung CORL95 3.5
Lung CPCN 3.8
Lung DMS114 4
Lung DMS153 4
Lung DMS273 3.9
Lung DMS454 3.9
Lung DMS53 3.9
Lung DMS79 4.7
Lung DV90 4.3
Lung EBC1 3.9
Lung EPLC272H 4.1
Lung HARA 4.1
Lung HCC1171 4
Lung HCC1195 4.1
Lung HCC15 3.8
Lung HCC2279 4
Lung HCC2935 3.9
Lung HCC33 4
Lung HCC366 3.9
Lung HCC4006 4
Lung HCC44 4
Lung HCC78 4
Lung HCC827 4.1
Lung HCC95 3.8
Lung HLC1 4
Lung HLFA 3.9
Lung HS229T 4.1
Lung HS618T 4.2
Lung IALM 4
Lung KNS62 3.9
Lung LC1F 4.1
Lung LC1SQSF 3.8
Lung LCLC103H 3.9
Lung LCLC97TM1 3.8
Lung LK2 4
Lung LOUNH91 4
Lung LU65 4
Lung LU99 4.1
Lung LUDLU1 3.7
Lung LXF289 3.9
Lung MORCPR 4
Lung NCIH1048 4.2
Lung NCIH1092 4
Lung NCIH1105 3.8
Lung NCIH1155 4.2
Lung NCIH1184 3.9
Lung NCIH1299 4
Lung NCIH1339 3.9
Lung NCIH1341 4.2
Lung NCIH1355 4
Lung NCIH1373 3.8
Lung NCIH1385 5.9
Lung NCIH1395 3.9
Lung NCIH1435 4.2
Lung NCIH1436 3.7
Lung NCIH1437 4.1
Lung NCIH146 3.9
Lung NCIH1563 4.1
Lung NCIH1568 3.7
Lung NCIH1573 3.8
Lung NCIH1581 3.7
Lung NCIH1618 4.1
Lung NCIH1623 4
Lung NCIH1648 4.1
Lung NCIH1650 3.6
Lung NCIH1651 4.1
Lung NCIH1666 4
Lung NCIH1693 3.9
Lung NCIH1694 4.1
Lung NCIH1703 4.2
Lung NCIH1734 5.6
Lung NCIH1755 4.3
Lung NCIH1781 4.1
Lung NCIH1792 4.2
Lung NCIH1793 4.1
Lung NCIH1836 4.1
Lung NCIH1838 4.2
Lung NCIH1869 3.8
Lung NCIH1876 4
Lung NCIH1915 4
Lung NCIH1930 4.1
Lung NCIH1944 4.2
Lung NCIH1963 4.3
Lung NCIH196 4.3
Lung NCIH1975 4.2
Lung NCIH2009 4
Lung NCIH2023 4.2
Lung NCIH2029 4.6
Lung NCIH2030 3.9
Lung NCIH2066 3.9
Lung NCIH2081 4.5
Lung NCIH2085 6.1
Lung NCIH2087 4.2
Lung NCIH209 5.6
Lung NCIH2106 4
Lung NCIH2110 3.8
Lung NCIH211 4.6
Lung NCIH2122 3.8
Lung NCIH2126 3.8
Lung NCIH2141 3.8
Lung NCIH2170 4.5
Lung NCIH2171 4.2
Lung NCIH2172 4
Lung NCIH2196 4.1
Lung NCIH2227 3.7
Lung NCIH2228 4.4
Lung NCIH226 3.7
Lung NCIH2286 4
Lung NCIH2291 4.2
Lung NCIH2342 4.1
Lung NCIH2347 3.9
Lung NCIH23 4.5
Lung NCIH2405 4
Lung NCIH2444 4.3
Lung NCIH292 5.3
Lung NCIH322 4.2
Lung NCIH3255 4.1
Lung NCIH358 4
Lung NCIH441 4.3
Lung NCIH446 3.8
Lung NCIH460 4.2
Lung NCIH510 3.9
Lung NCIH520 4
Lung NCIH522 4
Lung NCIH524 4.1
Lung NCIH526 4.3
Lung NCIH596 3.8
Lung NCIH647 3.6
Lung NCIH650 3.8
Lung NCIH661 3.9
Lung NCIH69 4.3
Lung NCIH727 3.8
Lung NCIH810 4.3
Lung NCIH82 4.4
Lung NCIH838 4.1
Lung NCIH841 3.8
Lung NCIH854 4
Lung NCIH889 4.1
Lung PC14 3.8
Lung RERFLCAD1 3.9
Lung RERFLCAD2 4.1
Lung RERFLCAI 4.3
Lung RERFLCKJ 4
Lung RERFLCMS 4
Lung RERFLCSQ1 4
Lung SBC5 3.8
Lung SCLC21H 3.7
Lung SHP77 3.8
Lung SKLU1 4.4
Lung SKMES1 3.9
Lung SQ1 4
Lung SW1271 4.3
Lung SW1573 4
Lung SW900 4.3
Lung VMRCLCD 4.3
Lung VMRCLCP 4.4
Oesophagus COLO680N 3.9
Oesophagus ECGI10 4
Oesophagus KYSE140 4
Oesophagus KYSE150 4.1
Oesophagus KYSE180 4.2
Oesophagus KYSE270 3.8
Oesophagus KYSE30 3.9
Oesophagus KYSE410 4.2
Oesophagus KYSE450 4.1
Oesophagus KYSE510 4.2
Oesophagus KYSE520 3.9
Oesophagus KYSE70 3.8
Oesophagus OE19 3.9
Oesophagus OE33 3.9
Oesophagus TE10 3.9
Oesophagus TE11 4.1
Oesophagus TE14 3.9
Oesophagus TE15 4.3
Oesophagus TE1 3.9
Oesophagus TE4 3.9
Oesophagus TE5 4
Oesophagus TE6 4
Oesophagus TE8 4.1
Oesophagus TE9 4.1
Oesophagus TT 4.4
Ovary 59M 4.2
Ovary A2780 4.3
Ovary CAOV3 5
Ovary CAOV4 4
Ovary COLO704 4.9
Ovary COV318 4.3
Ovary COV362 3.9
Ovary COV434 4.1
Ovary COV504 4
Ovary COV644 4
Ovary EFO21 3.8
Ovary EFO27 4.1
Ovary ES2 3.8
Ovary FUOV1 4.3
Ovary HEYA8 4
Ovary HS571T 4.1
Ovary IGROV1 4.6
Ovary JHOC5 4.1
Ovary JHOM1 3.9
Ovary JHOM2B 3.9
Ovary JHOS2 4
Ovary JHOS4 3.8
Ovary KURAMOCHI 3.9
Ovary MCAS 4.1
Ovary NIHOVCAR3 3.9
Ovary OAW28 3.8
Ovary OAW42 4.2
Ovary OC314 4.2
Ovary OC316 4
Ovary ONCODG1 3.7
Ovary OV56 3.9
Ovary OV7 4.1
Ovary OV90 3.9
Ovary OVCAR4 4.7
Ovary OVCAR8 3.7
Ovary OVISE 3.7
Ovary OVK18 4.3
Ovary OVKATE 4
Ovary OVMANA 4.1
Ovary OVSAHO 4.1
Ovary OVTOKO 3.9
Ovary RMGI 4
Ovary RMUGS 3.9
Ovary SKOV3 3.9
Ovary SNU119 4
Ovary SNU840 3.7
Ovary SNU8 4.2
Ovary TOV112D 3.9
Ovary TOV21G 4.1
Ovary TYKNU 3.6
Pancreas ASPC1 4.2
Pancreas BXPC3 4.2
Pancreas CAPAN1 4
Pancreas CAPAN2 4.1
Pancreas CFPAC1 3.9
Pancreas DANG 3.9
Pancreas HPAC 4.2
Pancreas HPAFII 4.2
Pancreas HS766T 3.8
Pancreas HUPT3 4.1
Pancreas HUPT4 4.1
Pancreas KCIMOH1 3.8
Pancreas KLM1 4.3
Pancreas KP2 3.8
Pancreas KP3 4.1
Pancreas KP4 4.1
Pancreas L33 4
Pancreas MIAPACA2 4.6
Pancreas PANC0203 4
Pancreas PANC0213 4
Pancreas PANC0327 4
Pancreas PANC0403 4
Pancreas PANC0504 3.9
Pancreas PANC0813 4.2
Pancreas PANC1005 4
Pancreas PANC1 4.1
Pancreas PATU8902 4.3
Pancreas PATU8988S 4.2
Pancreas PATU8988T 4
Pancreas PK1 4
Pancreas PK45H 3.7
Pancreas PK59 4
Pancreas PL45 4
Pancreas PSN1 4.3
Pancreas QGP1 4
Pancreas SNU213 4.2
Pancreas SNU324 3.9
Pancreas SNU410 3.8
Pancreas SU8686 3.9
Pancreas SUIT2 3.9
Pancreas SW1990 3.9
Pancreas T3M4 3.7
Pancreas TCCPAN2 4
Pancreas YAPC 3.9
Pleura ACCMESO1 4
Pleura DM3 3.9
Pleura ISTMES1 4.3
Pleura ISTMES2 4.2
Pleura JL1 4.1
Pleura MPP89 4.5
Pleura MSTO211H 4
Pleura NCIH2052 3.8
Pleura NCIH2452 4
Pleura NCIH28 4.1
Prostate 22RV1 4.1
Prostate DU145 4
Prostate LNCAPCLONEFGC 3.7
Prostate MDAPCA2B 4.2
Prostate NCIH660 3.8
Prostate PC3 4
Prostate VCAP 3.8
Salivary gland A253 3.6
Salivary gland YD15 4.2
Skin A101D 4
Skin A2058 4.1
Skin A375 3.7
Skin C32 3.9
Skin CHL1 3.9
Skin CJM 3.9
Skin COLO679 3.9
Skin COLO741 3.9
Skin COLO783 3.7
Skin COLO792 4
Skin COLO800 4
Skin COLO818 3.6
Skin COLO829 3.9
Skin COLO849 4
Skin G361 3.8
Skin GRM 4.4
Skin HMCB 4.4
Skin HS294T 3.8
Skin HS600T 4.2
Skin HS688AT 4.2
Skin HS695T 4
Skin HS839T 4
Skin HS852T 4.2
Skin HS895T 4.3
Skin HS934T 3.9
Skin HS936T 4
Skin HS939T 3.8
Skin HS940T 4.1
Skin HS944T 3.8
Skin HT144 4.1
Skin IGR1 4
Skin IGR37 4.4
Skin IGR39 3.8
Skin IPC298 4.3
Skin K029AX 4
Skin LOXIMVI 4.4
Skin MALME3M 3.8
Skin MDAMB435S 4.1
Skin MELHO 4
Skin MELJUSO 4
Skin MEWO 3.9
Skin RPMI7951 3.7
Skin RVH421 4.2
Skin SH4 4
Skin SKMEL1 4
Skin SKMEL24 4
Skin SKMEL28 4.1
Skin SKMEL2 3.7
Skin SKMEL30 4.1
Skin SKMEL31 3.8
Skin SKMEL3 3.8
Skin SKMEL5 4.1
Skin UACC257 4
Skin UACC62 4.3
Skin WM115 4
Skin WM1799 4
Skin WM2664 3.9
Skin WM793 3.9
Skin WM88 3.8
Skin WM983B 3.9
Small intestine HUTU80 3.9
Soft tissue A204 3.9
Soft tissue G401 4
Soft tissue G402 4.1
Soft tissue GCT 4
Soft tissue HS729 4
Soft tissue HT1080 4.2
Soft tissue KYM1 3.9
Soft tissue MESSA 4.2
Soft tissue RD 9.2
Soft tissue RH30 5.1
Soft tissue RH41 4.4
Soft tissue RKN 3.9
Soft tissue S117 4.3
Soft tissue SJRH30 4.1
Soft tissue SKLMS1 3.9
Soft tissue SKUT1 4.2
Soft tissue TE125T 3.8
Soft tissue TE159T 4.3
Soft tissue TE441T 3.9
Soft tissue TE617T 4.3
Stomach 2313287 4.2
Stomach AGS 4.2
Stomach AZ521 4
Stomach ECC10 4.2
Stomach ECC12 4.2
Stomach FU97 4.3
Stomach GCIY 4.1
Stomach GSS 3.8
Stomach GSU 4.3
Stomach HGC27 3.9
Stomach HS746T 4.1
Stomach HUG1N 4
Stomach IM95 4.3
Stomach KATOIII 4
Stomach KE39 3.8
Stomach LMSU 4.3
Stomach MKN1 4.2
Stomach MKN45 3.9
Stomach MKN74 4.1
Stomach MKN7 4.1
Stomach NCCSTCK140 4.3
Stomach NCIN87 3.7
Stomach NUGC2 4.1
Stomach NUGC3 4
Stomach NUGC4 3.9
Stomach OCUM1 4
Stomach RERFGC1B 4.3
Stomach SH10TC 4.2
Stomach SNU16 3.8
Stomach SNU1 4.3
Stomach SNU216 4.1
Stomach SNU520 4.2
Stomach SNU5 4
Stomach SNU601 4.1
Stomach SNU620 4
Stomach SNU668 4.4
Stomach SNU719 4.3
Stomach TGBC11TKB 4.2
Thyroid 8305C 4.1
Thyroid 8505C 4
Thyroid BCPAP 4.1
Thyroid BHT101 4
Thyroid CAL62 4.1
Thyroid CGTHW1 3.7
Thyroid FTC133 3.9
Thyroid FTC238 3.8
Thyroid ML1 3.9
Thyroid SW579 3.9
Thyroid TT2609C02 4.3
Thyroid TT 3.8
Upper aerodigestive tract BHY 3.7
Upper aerodigestive tract BICR16 4.3
Upper aerodigestive tract BICR18 4
Upper aerodigestive tract BICR22 4.1
Upper aerodigestive tract BICR31 3.8
Upper aerodigestive tract BICR56 3.9
Upper aerodigestive tract BICR6 4.3
Upper aerodigestive tract CAL27 4
Upper aerodigestive tract CAL33 3.9
Upper aerodigestive tract DETROIT562 4
Upper aerodigestive tract FADU 4
Upper aerodigestive tract HS840T 4
Upper aerodigestive tract HSC2 4
Upper aerodigestive tract HSC3 4.6
Upper aerodigestive tract HSC4 3.7
Upper aerodigestive tract PECAPJ15 3.8
Upper aerodigestive tract PECAPJ34CLONEC12 4
Upper aerodigestive tract PECAPJ41CLONED2 4.3
Upper aerodigestive tract PECAPJ49 4.3
Upper aerodigestive tract SCC15 3.8
Upper aerodigestive tract SCC25 4.1
Upper aerodigestive tract SCC4 3.9
Upper aerodigestive tract SCC9 3.8
Upper aerodigestive tract SNU1076 3.9
Upper aerodigestive tract SNU1214 3.6
Upper aerodigestive tract SNU46 3.6
Upper aerodigestive tract SNU899 4.1
Upper aerodigestive tract YD10B 4
Upper aerodigestive tract YD38 3.9
Upper aerodigestive tract YD8 4.1
Urinary tract 5637 4
Urinary tract 639V 4.4
Urinary tract 647V 5.4
Urinary tract BC3C 3.9
Urinary tract BFTC905 4
Urinary tract CAL29 4.8
Urinary tract HS172T 3.7
Urinary tract HT1197 3.7
Urinary tract HT1376 4.9
Urinary tract J82 4.3
Urinary tract JMSU1 3.9
Urinary tract KMBC2 3.7
Urinary tract KU1919 4.1
Urinary tract RT11284 3.9
Urinary tract RT112 4.1
Urinary tract RT4 3.8
Urinary tract SCABER 4
Urinary tract SW1710 4.1
Urinary tract SW780 4.5
Urinary tract T24 3.9
Urinary tract TCCSUP 4.4
Urinary tract UMUC1 4.1
Urinary tract UMUC3 3.9
Urinary tract VMCUB1 3.9
> The Human Protein Atlas (HPA)
 


Tissue Expression Level (TPM)
Adipose tissue 3.8
Adrenal gland 0.5
Appendix 2.3
Bone marrow 0.2
Breast 5.1
Cerebral cortex 1.8
Cervix, uterine 0.1
Colon 0.7
Duodenum 0.3
Endometrium 0.7
Epididymis 0
Esophagus 645.1
Fallopian tube 0.1
Gallbladder 2.7
Heart muscle 2575.1
Kidney 1.9
Liver 0.1
Lung 0.2
Lymph node 2.4
Ovary 0
Pancreas 0
Parathyroid gland 0
Placenta 1.7
Prostate 194.4
Rectum 0
Salivary gland 0.1
Seminal vesicle 1
Skeletal muscle 45988
Skin 0.7
Small intestine 0.4
Smooth muscle 90.1
Spleen 0.1
Stomach 0.4
Testis 0.1
Thyroid gland 3
Tonsil 0.9
Urinary bladder 6.6
> Text Mining based Expression
 
PMID Expression Cancer Evidence
27416733underexpressionLip and Oral Cavity CarcinomaLow expression of ASMA in stromal vessels and a strong tumor invasion front were significantly associated to tumor recurrence (P=0.024 and P=0.004, respectively)
26950277underexpressionLung AdenocarcinomaActivin A (ActA)/follistatin (FST) signaling has been shown to be deregulated in different tumor types including lung adenocarcinoma (LADC).
25921136overexpressionPapillary CarcinomaASMA was not expressed in benign papillary hyperplastic lesions while it was expressed in papillary carcinoma, indicating that tumors have modulated stroma.
22846364underexpressionBuccal Mucosa Verrucous CarcinomaThe down-regulation of four of these transcripts MYL1, ACTA1, TCAP and DESMIN in buccal cancer were further supported by quantitative PCR signifying its possible implication in the cancer progression
22558481aberrant expressionAdenoid Cystic CarcinomaImmunohistochemically, the tumor cells were positive for cytokeratin (CK) AE1/3, CK34BE12, CK5/6, CK7, CK14, p63, alpha-smooth muscle actin (ASMA), S100 protein, p53, Ki-67 (labeling 85%), KIT, PDGFRA and CD56.
21725291aberrant expressionCutaneous Myoepithelial TumorImmunohistochemically, all cases tested were positive for EMA and calponin, whereas S100, CK, ASMA and GFAP were expressed in 90%, 80%, 78% and 50% of the cases tested, respectively.
16330949aberrant expressionMyopericytomaImmunohistochemically, all cases tested stained positively for ASMA.
12354798altered expressionGastric Cancer Stroma Cell; Gastric Cancer CarcinomaIn the 24 diffuse-type gastric carcinomas, six of the 13 carcinomas invading the subserosa had ASMA+ cells in the tumour stroma, whereas all six diffuse-type gastric carcinomas confined to the submucosa and all five invading the muscularis propria had no ASMA+ cells in the tumour stroma; In the 43 intestinal-type gastric carcinomas, only five of the 21 carcinomas confined to the submucosa had ASMA+ cells in the tumour stroma, whereas 21 of the 22 intestinal-type gastric carcinomas invading the muscularis propria and the subserosa had ASMA+ cell bundles in the tumour stroma; All seven solid-type gastric carcinomas examined had ASMA+ cells but not CD34+ cells in the tumour stroma
12066202aberrant expressionRenomedullary Interstitial Cell TumorCD35-positive cells (dendritic cells) and ASMA-positive cells were observed in all the tumors, with a more frequent occurrence in the cellular type than the fibrous type.
11350610loss of expressionPhyllodes TumorHowever, they showed no immunoreaction to CAM 5.2, desmin, alpha-smooth muscle actin (ASMA), neuron-specific enolase (NSE) nor S-100.
1653908aberrant expressionGliosarcomaSpindle cells in reticulin-rich areas of 'gliosarcomas' and glioblastomas most frequently expressed ASMA but many cells also expressed S100 protein and GFAP; some cells expressed both GFAP and ASMA.
28712119OverexpressionColorectal Carcinoma; Lung CarcinomaPatients with high ActA (≥408pg/mL) had lower OS than those with low levels, regardless the type of cancer (OS in colorectal cancer, 50% vs. 79%, P<0.05; and in lung cancer, 27% vs. 67%, P=0.001).
28533055OverexpressionBreast CarcinomaA total of 127 breast samples, including 96 malignant and 31 benign, were examined for ASMA, HMGB1, and RAGE by immunohistochemistry. ASMA+ fibroblast infiltration was significantly increased in the tumor stroma compared with that in benign breast tissue. The levels of cytoplasmic HMGB1 and RAGE were significantly greater in the breast cancer tissue than in the benign breast tissues. High ASMA expression correlated significantly with large tumor size, clinical stage III-IV, and angiolymphatic and perinodal invasion.
Summary
SymbolACTA1
Nameactin, alpha 1, skeletal muscle
Aliases NEM3; nemaline myopathy type 3; ACTA; ASMA; CFTD1; Alpha-actin-1; Actin, alpha skeletal muscle
Location1q42.13
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Somatic copy number alteration in primary tomur tissue
> The Cancer Genome Atlas (TCGA)
 


  Correlation between expression and SCNA as well as percentage of patients in different status.
Cancer Full Name # Sample R P % Loss % Neutral % Gain Status
BLCABladder urothelial carcinoma4040.1830.00021313.453.233.4Gain
BRCABreast invasive carcinoma10750.1711.78e-082.523.873.7Gain
GBMGlioblastoma multiforme1470.1170.1586.177.616.3Neutral
HNSCHead and Neck squamous cell carcinoma514-0.0910.03826.86627.2Neutral
LGGBrain Lower Grade Glioma5130.0460.35.388.95.8Neutral
LUADLung adenocarcinoma5120.0660.1394.928.366.8Gain
OVOvarian serous cystadenocarcinoma3000.0770.1838.33754.7Gain
PCPGPheochromocytoma and Paraganglioma1620.0770.32912.374.113.6Neutral
PRADProstate adenocarcinoma4910.0080.862985.15.9Neutral
SARCSarcoma2550.1650.0084834.151.814.1Loss
SKCMSkin Cutaneous Melanoma3670.080.125642.251.8Gain
STADStomach adenocarcinoma4130.0780.1124.864.430.8Neutral
TGCTTesticular Germ Cell Tumors1500.1820.02584.749.346Gain
THYMThymoma1190.2710.002850.875.623.5Neutral
UCECUterine Corpus Endometrial Carcinoma5370.2051.67e-0625741Gain
Summary
SymbolACTA1
Nameactin, alpha 1, skeletal muscle
Aliases NEM3; nemaline myopathy type 3; ACTA; ASMA; CFTD1; Alpha-actin-1; Actin, alpha skeletal muscle
Location1q42.13
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Methylation level in the promoter region of CR
> Methylation level in the promoter region of CR
 


  Correlation between expression and methylation as well as differential methylation analysis.
Cancer Full Name R P # N # T Delta beta (T vs N) P value (T vs N) Status
BLCABladder urothelial carcinoma-0.0960.0468174080.1334.71e-10NS/NA
BRCABreast invasive carcinoma-0.1911.52e-0883785-0.0030.00386NS/NA
GBMGlioblastoma multiforme-0.2920.0185164NANANS/NA
HNSCHead and Neck squamous cell carcinoma-0.1320.00205205220.2976.58e-16Increased
LGGBrain Lower Grade Glioma-0.1270.003510530NANANS/NA
LUADLung adenocarcinoma-0.0540.24214560.0263.77e-08NS/NA
OVOvarian serous cystadenocarcinoma-0.40.29109NANANS/NA
PCPGPheochromocytoma and Paraganglioma-0.4193.25e-093184NANANS/NA
PRADProstate adenocarcinoma-0.358.96e-17354980.2441.57e-12Increased
SARCSarcoma-0.220.000340263NANANS/NA
SKCMSkin Cutaneous Melanoma0.0110.8181471NANANS/NA
STADStomach adenocarcinoma-0.2585.18e-070372NANANS/NA
TGCTTesticular Germ Cell Tumors-0.4651.53e-090156NANANS/NA
THYMThymoma-0.0910.3172120NANANS/NA
UCECUterine Corpus Endometrial Carcinoma-0.1170.0115344310.0012.64e-08NS/NA
Summary
SymbolACTA1
Nameactin, alpha 1, skeletal muscle
Aliases NEM3; nemaline myopathy type 3; ACTA; ASMA; CFTD1; Alpha-actin-1; Actin, alpha skeletal muscle
Location1q42.13
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Primary tumor tissue from TCGA
> Normal tumor tissue from HPA
>The Cancer Genome Atlas (TCGA)
 
There is no record.
> The Human Protein Atlas (HPA)
 


Tissue Level Level Name
Adrenal gland 0 Not detected
Appendix 0 Not detected
Bone marrow 0 Not detected
Breast 2 Medium
Bronchus 0 Not detected
Caudate 0 Not detected
Cerebellum 0 Not detected
Cerebral cortex 0 Not detected
Cervix, uterine 0 Not detected
Colon 0 Not detected
Duodenum 0 Not detected
Endometrium 0 Not detected
Epididymis 0 Not detected
Esophagus 0 Not detected
Fallopian tube 0 Not detected
Gallbladder 0 Not detected
Heart muscle 3 High
Hippocampus 0 Not detected
Kidney 0 Not detected
Liver 0 Not detected
Lung 0 Not detected
Lymph node 0 Not detected
Nasopharynx 0 Not detected
Oral mucosa 0 Not detected
Ovary 0 Not detected
Pancreas 0 Not detected
Parathyroid gland 0 Not detected
Placenta 0 Not detected
Prostate 0 Not detected
Rectum 0 Not detected
Salivary gland 0 Not detected
Seminal vesicle 0 Not detected
Skeletal muscle 3 High
Skin 0 Not detected
Small intestine 0 Not detected
Smooth muscle 3 High
Soft tissue 0 Not detected
Spleen 0 Not detected
Stomach 0 Not detected
Testis 0 Not detected
Thyroid gland 0 Not detected
Tonsil 0 Not detected
Urinary bladder 0 Not detected
Vagina 0 Not detected
Summary
SymbolACTA1
Nameactin, alpha 1, skeletal muscle
Aliases NEM3; nemaline myopathy type 3; ACTA; ASMA; CFTD1; Alpha-actin-1; Actin, alpha skeletal muscle
Location1q42.13
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Association between expresson and subtype
> Overall survival analysis based on expression
> Association between expresson and stage
> Association between expresson and grade
> Subtype
 


  Association between expresson and subtype.
Cancer Full Name # Patients P Value (Kruskal-Wallis) Association Source
BLCABladder urothelial carcinoma1280.975NS24476821
BRCABreast invasive carcinoma5210.0276Significant23000897
GBMGlioblastoma multiforme1570.0998NS26824661
HNSCHead and Neck squamous cell carcinoma2791.05e-08Significant25631445
LGGBrain Lower Grade Glioma5130.35NS26824661
LUADLung adenocarcinoma2300.466NS25079552
OVOvarian serous cystadenocarcinoma2876.26e-05Significant21720365
PRADProstate adenocarcinoma3330.154NS26544944
SKCMSkin Cutaneous Melanoma3150.383NS26091043
STADStomach adenocarcinoma2770.000699Significant25079317
UCECUterine Corpus Endometrial Carcinoma2320.0305Significant23636398
> Overall survival
 

  Overall survival analysis based on expression.
Cancer Full Name # Patients Hazard Ratio P Value (Log Rank Test) Association
BLCABladder urothelial carcinoma405 1.1270.583NS
BRCABreast invasive carcinoma1079 0.920.713NS
GBMGlioblastoma multiforme158 1.420.176NS
HNSCHead and Neck squamous cell carcinoma518 1.6630.013Shorter
LGGBrain Lower Grade Glioma511 0.970.894NS
LUADLung adenocarcinoma502 1.270.234NS
OVOvarian serous cystadenocarcinoma303 0.6910.0819NS
PCPGPheochromocytoma and Paraganglioma179 0.6310.713NS
PRADProstate adenocarcinoma497 0.6410.614NS
SARCSarcoma259 0.8170.478NS
SKCMSkin Cutaneous Melanoma459 1.4220.0691NS
STADStomach adenocarcinoma388 1.6420.0277Shorter
TGCTTesticular Germ Cell Tumors134 538880933.8030.18NS
THYMThymoma119 0.7680.75NS
UCECUterine Corpus Endometrial Carcinoma543 2.2680.00804Shorter
> Stage
 

  Association between expresson and stage.
Cancer Full Name # Patients R Value (Spearman) P Value (Spearman) Association
BLCABladder urothelial carcinoma406 0.0610.22NS
BRCABreast invasive carcinoma1071 -0.0410.175NS
HNSCHead and Neck squamous cell carcinoma448 -0.0940.0461Lower
LUADLung adenocarcinoma507 0.0730.0991NS
OVOvarian serous cystadenocarcinoma302 -0.0070.906NS
SKCMSkin Cutaneous Melanoma410 0.0260.594NS
STADStomach adenocarcinoma392 0.0120.813NS
TGCTTesticular Germ Cell Tumors81 0.380.000473Higher
UCECUterine Corpus Endometrial Carcinoma501 0.0390.386NS
> Grade
 

  Association between expresson and grade.
Cancer Full Name # Patients R Value (Spearman) P Value (Spearman) Association
HNSCHead and Neck squamous cell carcinoma498 -0.040.368NS
LGGBrain Lower Grade Glioma514 -0.0040.925NS
OVOvarian serous cystadenocarcinoma296 -0.0190.741NS
STADStomach adenocarcinoma406 0.0790.114NS
UCECUterine Corpus Endometrial Carcinoma534 0.0740.088NS
Summary
SymbolACTA1
Nameactin, alpha 1, skeletal muscle
Aliases NEM3; nemaline myopathy type 3; ACTA; ASMA; CFTD1; Alpha-actin-1; Actin, alpha skeletal muscle
Location1q42.13
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Targets inferred by reverse engineering method
> Targets identified by ChIP-seq data
> Targets inferred by reverse engineering method
 
> Targets identified by ChIP-seq data
 
Summary
SymbolACTA1
Nameactin, alpha 1, skeletal muscle
Aliases NEM3; nemaline myopathy type 3; ACTA; ASMA; CFTD1; Alpha-actin-1; Actin, alpha skeletal muscle
Location1q42.13
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Drugs from DrugBank database
> Drugs from DrugBank database
 
DrugBank ID Name Type All Targets
DB02621Latrunculin ASmall Molecule Drug
DB02772SucroseSmall Molecule Drug
DB03021Ulapualide ASmall Molecule Drug
DB03616Kabiramide CSmall Molecule Drug
DB03850Jaspisamide ASmall Molecule Drug
DB03903TmrSmall Molecule Drug
DB041514-Methyl-HistidineSmall Molecule Drug
DB04395Phosphoaminophosphonic Acid-Adenylate EsterSmall Molecule Drug
DB04629Aplyronine ASmall Molecule Drug
DB04774Reidispongiolide ASmall Molecule Drug
DB04775Reidispongiolide CSmall Molecule Drug
DB04783Sphinxolide BSmall Molecule Drug
DB08080LATRUNCULIN BSmall Molecule Drug
Summary
SymbolACTA1
Nameactin, alpha 1, skeletal muscle
Aliases NEM3; nemaline myopathy type 3; ACTA; ASMA; CFTD1; Alpha-actin-1; Actin, alpha skeletal muscle
Location1q42.13
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Protein-Protein Interaction Network
> miRNA Regulatory Relationship
> Interactions from Text Mining
> Protein-Protein Interaction Network
 
> miRNA Regulatory Relationship
 
> Interactions from Text Mining
 
There is no record for ACTA1.