CR2Cancer

Summary
Symbol	ARID2
Name	AT-rich interaction domain 2
Aliases	KIAA1557; DKFZp686G052; FLJ30619; BAF200; ARID domain-containing protein 2; BRG1-associated factor 200; zinc ......
Location	12q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

[ TOP ]

Domain

PF01388 ARID/BRIGHT DNA binding domain
PF02257 RFX DNA-binding domain

Function

Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes.

Classification

Class	Modification	Substrate	Product	PubMed
Chromatin remodelling cofactor	#	DNA motif	#	15640446

> Gene Ontology [ TOP ]
Biological Process	GO:0006333 chromatin assembly or disassembly GO:0006337 nucleosome disassembly GO:0030336 negative regulation of cell migration GO:0031498 chromatin disassembly GO:0032984 macromolecular complex disassembly GO:0032986 protein-DNA complex disassembly GO:0034728 nucleosome organization GO:0040013 negative regulation of locomotion GO:0043241 protein complex disassembly GO:0051271 negative regulation of cellular component movement GO:0071824 protein-DNA complex subunit organization GO:2000146 negative regulation of cell motility
Molecular Function	-
Cellular Component	GO:0070603 SWI/SNF superfamily-type complex GO:0090544 BAF-type complex

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	R-HSA-3247509: Chromatin modifying enzymes R-HSA-4839726: Chromatin organization R-HSA-3214858: RMTs methylate histone arginines

Summary
Symbol	ARID2
Name	AT-rich interaction domain 2
Aliases	KIAA1557; DKFZp686G052; FLJ30619; BAF200; ARID domain-containing protein 2; BRG1-associated factor 200; zinc ......
Location	12q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM4498307	c.5179C>T	p.P1727S	Substitution - Missense	Skin
COSM3704150	c.5188C>T	p.Q1730*	Substitution - Nonsense	Liver
COSM1167991	c.890C>T	p.S297F	Substitution - Missense	Skin
COSM1606141	c.3817C>T	p.R1273*	Substitution - Nonsense	Liver
COSM5990675	c.1057C>T	p.H353Y	Substitution - Missense	Liver
COSM2067827	c.2276C>T	p.S759F	Substitution - Missense	Large_intestine
COSM3704148	c.4844T>G	p.F1615C	Substitution - Missense	Liver
COSM939513	c.4535_4545del11	p.C1512fs*1	Deletion - Frameshift	Endometrium
COSM693903	c.3298C>G	p.Q1100E	Substitution - Missense	Lung
COSM1628612	c.4717delG	p.A1573fs*53	Deletion - Frameshift	Liver
COSM1628601	c.206G>A	p.W69*	Substitution - Nonsense	Liver
COSM1512173	c.1426C>T	p.Q476*	Substitution - Nonsense	Liver
COSM1606149	c.5001T>G	p.C1667W	Substitution - Missense	Liver
COSM4804483	c.3790G>T	p.E1264*	Substitution - Nonsense	Liver
COSM5990677	c.1510G>A	p.V504I	Substitution - Missense	Liver
COSM5647552	c.3980C>G	p.S1327*	Substitution - Nonsense	Oesophagus
COSM1361683	c.1277C>T	p.T426M	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM231543	c.2872_2873insA	p.T959fs*9	Insertion - Frameshift	Skin
COSM1512174	c.820C>T	p.R274*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM3460962	c.699C>T	p.F233F	Substitution - coding silent	Skin
COSM6006349	c.1774G>A	p.A592T	Substitution - Missense	Skin
COSM4608448	c.1151C>A	p.A384E	Substitution - Missense	Adrenal_gland
COSM5607875	c.5359C>A	p.R1787S	Substitution - Missense	Skin
COSM1245454	c.1624C>T	p.R542*	Substitution - Nonsense	Skin
COSM2067836	c.2802A>G	p.Q934Q	Substitution - coding silent	Large_intestine
COSM6006358	c.2527C>T	p.Q843*	Substitution - Nonsense	Skin
COSM1167907	c.5147+1G>A	p.?	Unknown	Skin
COSM3460964	c.862C>T	p.Q288*	Substitution - Nonsense	Skin
COSM5704454	c.3613G>T	p.G1205*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM1245459	c.3370C>T	p.Q1124*	Substitution - Nonsense	Liver
COSM5047834	c.947T>C	p.L316P	Substitution - Missense	Oesophagus
COSM3704146	c.2045C>G	p.S682*	Substitution - Nonsense	Liver
COSM3460969	c.2173C>T	p.Q725*	Substitution - Nonsense	Skin
COSM4951169	c.5131C>T	p.Q1711*	Substitution - Nonsense	Liver
COSM218404	c.940C>A	p.R314S	Substitution - Missense	Pancreas
COSM1183571	c.1463A>G	p.Q488R	Substitution - Missense	Large_intestine
COSM3460971	c.2881C>T	p.Q961*	Substitution - Nonsense	Skin
COSM4949469	c.3277C>T	p.P1093S	Substitution - Missense	Skin
COSM2067865	c.4384C>T	p.Q1462*	Substitution - Nonsense	Oesophagus
COSM1361705	c.5239G>T	p.G1747*	Substitution - Nonsense	Large_intestine
COSM3460974	c.3121C>T	p.Q1041*	Substitution - Nonsense	Skin
COSM5985331	c.4565C>G	p.T1522S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM131035	c.4413_4419delACATTCT	p.H1472fs*11	Deletion - Frameshift	Liver
COSM3416866	c.4929T>C	p.F1643F	Substitution - coding silent	Large_intestine
COSM4565485	c.2145_2146GG>AA	p.A716T	Substitution - Missense	Skin
COSM1361687	c.1418C>A	p.S473Y	Substitution - Missense	Large_intestine
COSM1316398	c.2909C>G	p.P970R	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1183566	c.2003C>A	p.S668Y	Substitution - Missense	Large_intestine
COSM1299387	c.5482G>C	p.E1828Q	Substitution - Missense	Urinary_tract
COSM1167929	c.2872C>T	p.Q958*	Substitution - Nonsense	Large_intestine
COSM4949549	c.4774-2A>G	p.?	Unknown	Liver
COSM1660623	c.4076A>G	p.N1359S	Substitution - Missense	Kidney
COSM939502	c.2011G>A	p.V671I	Substitution - Missense	Endometrium
COSM4663269	c.1801C>T	p.R601W	Substitution - Missense	Large_intestine
COSM2067785	c.356_366del11	p.K119fs*31	Deletion - Frameshift	Salivary_gland
COSM4799656	c.4923-2A>G	p.?	Unknown	Liver
COSM1167991	c.890C>T	p.S297F	Substitution - Missense	Skin
COSM1746980	c.4531G>T	p.E1511*	Substitution - Nonsense	Urinary_tract
COSM693909	c.1467C>T	p.V489V	Substitution - coding silent	Lung
COSM3871640	c.1917C>T	p.I639I	Substitution - coding silent	Skin
COSM957513	c.1_5508del5508	p.0?	Whole gene deletion	Liver
COSM5651280	c.3454C>T	p.P1152S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1361683	c.1277C>T	p.T426M	Substitution - Missense	Large_intestine
COSM4593385	c.4663G>T	p.A1555S	Substitution - Missense	Upper_aerodigestive_tract
COSM251424	c.1802G>A	p.R601Q	Substitution - Missense	Liver
COSM3739668	c.187-1G>A	p.?	Unknown	Liver
COSM278971	c.940C>T	p.R314C	Substitution - Missense	Skin
COSM5654237	c.2715A>C	p.Q905H	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM212790	c.2455C>T	p.Q819*	Substitution - Nonsense	Breast
COSM4949597	c.4532delA	p.E1511fs*5	Deletion - Frameshift	Liver
COSM251369	c.1507_1508insAG	p.A503fs*4	Insertion - Frameshift	Liver
COSM4754289	c.1805G>T	p.R602M	Substitution - Missense	Stomach
COSM5725619	c.992G>A	p.G331D	Substitution - Missense	Skin
COSM1746979	c.2337A>T	p.V779V	Substitution - coding silent	Urinary_tract
COSM693914	c.155C>T	p.T52I	Substitution - Missense	Lung
COSM1606139	c.3433_3434insT	p.S1146fs*14	Insertion - Frameshift	Liver
COSM5048054	c.2644G>T	p.G882C	Substitution - Missense	Oesophagus
COSM4949786	c.4031_4032ins68	p.I1344fs*5	Insertion - Frameshift	Liver
COSM5348617	c.1083_1084insA	p.C362fs*7	Insertion - Frameshift	Liver
COSM278971	c.940C>T	p.R314C	Substitution - Missense	Large_intestine
COSM939495	c.739C>A	p.R247S	Substitution - Missense	Endometrium
COSM1361690	c.1764_1765insAAT	p.N589_G590insN	Insertion - In frame	Large_intestine
COSM5548899	c.5318C>T	p.A1773V	Substitution - Missense	Prostate
COSM1361697	c.3203_3205delGTG	p.G1069delG	Deletion - In frame	Large_intestine
COSM107635	c.3127C>T	p.Q1043*	Substitution - Nonsense	Stomach
COSM1685691	c.4946_4947delTT	p.F1650fs*6	Deletion - Frameshift	Skin
COSM1512174	c.820C>T	p.R274*	Substitution - Nonsense	Skin
COSM2067882	c.4951T>C	p.Y1651H	Substitution - Missense	Large_intestine
COSM4399765	c.1468C>T	p.Q490*	Substitution - Nonsense	Skin
COSM5047368	c.3928G>C	p.G1310R	Substitution - Missense	Oesophagus
COSM459508	c.595A>G	p.I199V	Substitution - Missense	Urinary_tract
COSM4990228	c.5476G>A	p.E1826K	Substitution - Missense	Skin
COSM3460969	c.2173C>T	p.Q725*	Substitution - Nonsense	Skin
COSM1167991	c.890C>T	p.S297F	Substitution - Missense	Skin
COSM5375176	c.2953C>T	p.P985S	Substitution - Missense	Skin
COSM4041994	c.4496T>C	p.L1499P	Substitution - Missense	Stomach
COSM5506403	c.300C>T	p.Y100Y	Substitution - coding silent	Biliary_tract
COSM1245454	c.1624C>T	p.R542*	Substitution - Nonsense	Skin
COSM4663274	c.5306G>A	p.R1769Q	Substitution - Missense	Large_intestine
COSM5792878	c.3905C>T	p.S1302L	Substitution - Missense	Breast
COSM468374	c.94T>A	p.S32T	Substitution - Missense	Kidney
COSM5635060	c.5426C>T	p.S1809F	Substitution - Missense	Oesophagus
COSM5990680	c.3992G>A	p.G1331D	Substitution - Missense	Liver
COSM4984817	c.?	p.R80fs*10	Frameshift	Lung
COSM3739670	c.2324T>C	p.L775S	Substitution - Missense	Liver
COSM4450131	c.457delA	p.N153fs*62	Deletion - Frameshift	Skin
COSM4618996	c.1352C>G	p.S451C	Substitution - Missense	Large_intestine
COSM251412	c.1073C>G	p.T358S	Substitution - Missense	Liver
COSM1183572	c.881G>T	p.R294I	Substitution - Missense	Skin
COSM1188476	c.2743A>G	p.I915V	Substitution - Missense	Lung
COSM3665405	c.5022delT	p.Q1676fs*25	Deletion - Frameshift	Liver
COSM3460965	c.881G>A	p.R294K	Substitution - Missense	Skin
COSM236289	c.1868delG	p.R623fs*24	Deletion - Frameshift	Autonomic_ganglia
COSM5548899	c.5318C>T	p.A1773V	Substitution - Missense	Prostate
COSM5820146	c.5207A>T	p.H1736L	Substitution - Missense	Liver
COSM5967029	c.5382A>T	p.E1794D	Substitution - Missense	Pituitary
COSM4486034	c.3001C>T	p.P1001S	Substitution - Missense	Skin
COSM106761	c.430C>T	p.Q144*	Substitution - Nonsense	Skin
COSM939512	c.4198G>T	p.D1400Y	Substitution - Missense	Endometrium
COSM1606141	c.3817C>T	p.R1273*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM1361706	c.5348C>A	p.S1783*	Substitution - Nonsense	Large_intestine
COSM3460980	c.4425C>T	p.T1475T	Substitution - coding silent	Skin
COSM5348216	c.4533delA	p.E1511fs*5	Deletion - Frameshift	Liver
COSM1167927	c.3493C>T	p.Q1165*	Substitution - Nonsense	Skin
COSM5557523	c.2544A>G	p.I848M	Substitution - Missense	Prostate
COSM5490687	c.4585G>T	p.G1529*	Substitution - Nonsense	Biliary_tract
COSM693902	c.3429G>A	p.V1143V	Substitution - coding silent	Lung
COSM5735072	c.710G>A	p.W237*	Substitution - Nonsense	Pancreas
COSM217018	c.2134G>T	p.E712*	Substitution - Nonsense	Liver
COSM98118	c.2710C>T	p.Q904*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM5038915	c.920C>A	p.A307E	Substitution - Missense	Liver
COSM2067795	c.994C>T	p.L332F	Substitution - Missense	Oesophagus
COSM5051594	c.1079C>A	p.T360K	Substitution - Missense	Stomach
COSM1167991	c.890C>T	p.S297F	Substitution - Missense	Skin
COSM131033	c.200delA	p.N67fs*23	Deletion - Frameshift	Liver
COSM1606131	c.799G>T	p.E267*	Substitution - Nonsense	Biliary_tract
COSM1606133	c.1037C>T	p.P346L	Substitution - Missense	Liver
COSM1196491	c.1354A>G	p.M452V	Substitution - Missense	Lung
COSM693901	c.3592C>G	p.P1198A	Substitution - Missense	Lung
COSM3871640	c.1917C>T	p.I639I	Substitution - coding silent	Skin
COSM4804483	c.3790G>T	p.E1264*	Substitution - Nonsense	Liver
COSM1167951	c.2611C>T	p.Q871*	Substitution - Nonsense	Skin
COSM2067865	c.4384C>T	p.Q1462*	Substitution - Nonsense	Biliary_tract
COSM3968226	c.1126G>A	p.E376K	Substitution - Missense	Biliary_tract
COSM3460979	c.4351C>T	p.P1451S	Substitution - Missense	Skin
COSM3460967	c.1825C>T	p.Q609*	Substitution - Nonsense	Skin
COSM217018	c.2134G>T	p.E712*	Substitution - Nonsense	Liver
COSM4663270	c.3135G>A	p.S1045S	Substitution - coding silent	Large_intestine
COSM274040	c.541A>G	p.T181A	Substitution - Missense	Large_intestine
COSM939525	c.5148G>A	p.K1716K	Substitution - coding silent	Endometrium
COSM4771709	c.1023+6C>A	p.?	Unknown	Stomach
COSM1167927	c.3493C>T	p.Q1165*	Substitution - Nonsense	Skin
COSM939494	c.586G>T	p.D196Y	Substitution - Missense	Endometrium
COSM278971	c.940C>T	p.R314C	Substitution - Missense	Skin
COSM4399765	c.1468C>T	p.Q490*	Substitution - Nonsense	Skin
COSM1512174	c.820C>T	p.R274*	Substitution - Nonsense	Skin
COSM3986927	c.5062-1G>A	p.?	Unknown	Kidney
COSM1606135	c.1231G>T	p.D411Y	Substitution - Missense	Liver
COSM1628613	c.5147+3A>C	p.?	Unknown	Liver
COSM278971	c.940C>T	p.R314C	Substitution - Missense	Skin
COSM251411	c.5174C>G	p.S1725*	Substitution - Nonsense	Liver
COSM189021	c.853C>T	p.R285W	Substitution - Missense	Endometrium
COSM1299384	c.803C>T	p.S268F	Substitution - Missense	Urinary_tract
COSM3384360	c.3799G>T	p.E1267*	Substitution - Nonsense	Skin
COSM5375180	c.5109T>A	p.D1703E	Substitution - Missense	Skin
COSM1606136	c.2392C>T	p.Q798*	Substitution - Nonsense	Liver
COSM6008957	c.2377C>T	p.Q793*	Substitution - Nonsense	Large_intestine
COSM3460966	c.1787T>A	p.V596E	Substitution - Missense	Skin
COSM5456334	c.2255A>G	p.Q752R	Substitution - Missense	Large_intestine
COSM1245454	c.1624C>T	p.R542*	Substitution - Nonsense	Skin
COSM939506	c.2969C>T	p.S990L	Substitution - Missense	Endometrium
COSM131031	c.74_75insA	p.F26fs*10	Insertion - Frameshift	Liver
COSM1628603	c.755_756delAC	p.D252fs*6	Deletion - Frameshift	Liver
COSM5945939	c.3622A>G	p.T1208A	Substitution - Missense	Skin
COSM1606141	c.3817C>T	p.R1273*	Substitution - Nonsense	Oesophagus
COSM1183572	c.881G>T	p.R294I	Substitution - Missense	Large_intestine
COSM1196491	c.1354A>G	p.M452V	Substitution - Missense	Lung
COSM939499	c.1567T>G	p.F523V	Substitution - Missense	Endometrium
COSM1159250	c.1716-1G>A	p.?	Unknown	Skin
COSM3812047	c.1113G>C	p.K371N	Substitution - Missense	Breast
COSM3460969	c.2173C>T	p.Q725*	Substitution - Nonsense	Skin
COSM5953499	c.3007G>C	p.V1003L	Substitution - Missense	Oesophagus
COSM1361679	c.186+1G>A	p.?	Unknown	Large_intestine
COSM77290	c.2357G>C	p.G786A	Substitution - Missense	Ovary
COSM1705489	c.577C>T	p.L193F	Substitution - Missense	Skin
COSM4949549	c.4774-2A>G	p.?	Unknown	Liver
COSM4663273	c.4583C>T	p.A1528V	Substitution - Missense	Large_intestine
COSM3460971	c.2881C>T	p.Q961*	Substitution - Nonsense	Skin
COSM1159250	c.1716-1G>A	p.?	Unknown	Pancreas
COSM1683459	c.2610_2611insT	p.Q871fs*80	Insertion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM5375174	c.720C>T	p.I240I	Substitution - coding silent	Skin
COSM1167993	c.3937C>T	p.Q1313*	Substitution - Nonsense	Skin
COSM1476565	c.1653G>A	p.S551S	Substitution - coding silent	Breast
COSM1606150	c.5110G>T	p.E1704*	Substitution - Nonsense	Liver
COSM1245454	c.1624C>T	p.R542*	Substitution - Nonsense	Skin
COSM4479255	c.2308C>T	p.P770S	Substitution - Missense	Skin
COSM1606129	c.78delC	p.H27fs*31	Deletion - Frameshift	Liver
COSM5024923	c.1246A>T	p.I416F	Substitution - Missense	Breast
COSM278971	c.940C>T	p.R314C	Substitution - Missense	Skin
COSM5508136	c.3269delC	p.A1090fs*66	Deletion - Frameshift	Biliary_tract
COSM73727	c.1397A>C	p.K466T	Substitution - Missense	Ovary
COSM5346193	c.601A>C	p.T201P	Substitution - Missense	Urinary_tract
COSM215529	c.4576delA	p.T1526fs*9	Deletion - Frameshift	Central_nervous_system
COSM4950370	c.5390_5391delTA	p.L1797fs*6	Deletion - Frameshift	Liver
COSM5047858	c.3340C>A	p.Q1114K	Substitution - Missense	Oesophagus
COSM5945830	c.?_?del?	p.?	Unknown	Pleura
COSM258925	c.1349delT	p.S451fs*12	Deletion - Frameshift	Large_intestine
COSM939488	c.65A>G	p.E22G	Substitution - Missense	Endometrium
COSM3460968	c.2158C>T	p.Q720*	Substitution - Nonsense	Skin
COSM4754290	c.3670C>G	p.P1224A	Substitution - Missense	Stomach
COSM5704453	c.1716-1G>T	p.?	Unknown	Haematopoietic_and_lymphoid_tissue
COSM4995124	c.4493C>T	p.A1498V	Substitution - Missense	Upper_aerodigestive_tract
COSM1245454	c.1624C>T	p.R542*	Substitution - Nonsense	Central_nervous_system
COSM4776608	c.3943G>A	p.E1315K	Substitution - Missense	Breast
COSM693904	c.3044A>C	p.Q1015P	Substitution - Missense	Lung
COSM5735073	c.1026_1027insGA	p.L343fs*13	Insertion - Frameshift	Pancreas
COSM3460967	c.1825C>T	p.Q609*	Substitution - Nonsense	Skin
COSM1628609	c.1433T>A	p.L478*	Substitution - Nonsense	Liver
COSM1245454	c.1624C>T	p.R542*	Substitution - Nonsense	Skin
COSM957507	c.1580G>T	p.W527L	Substitution - Missense	Lung
COSM5002451	c.3124C>A	p.P1042T	Substitution - Missense	Pancreas
COSM5174078	c.5041_5042delTC	p.S1681fs*8	Deletion - Frameshift	Large_intestine
COSM213955	c.2776G>A	p.V926I	Substitution - Missense	Breast
COSM3460984	c.5026C>T	p.Q1676*	Substitution - Nonsense	Skin
COSM1183572	c.881G>T	p.R294I	Substitution - Missense	Large_intestine
COSM5742623	c.4922+1G>A	p.?	Unknown	Small_intestine
COSM5607878	c.4723C>T	p.Q1575*	Substitution - Nonsense	Skin
COSM4487836	c.3238C>T	p.P1080S	Substitution - Missense	Skin
COSM939527	c.5417A>T	p.E1806V	Substitution - Missense	Endometrium
COSM693915	c.78C>G	p.F26L	Substitution - Missense	Lung
COSM939526	c.5219C>T	p.A1740V	Substitution - Missense	Endometrium
COSM1606141	c.3817C>T	p.R1273*	Substitution - Nonsense	Oesophagus
COSM266035	c.925A>G	p.N309D	Substitution - Missense	Stomach
COSM1361683	c.1277C>T	p.T426M	Substitution - Missense	Large_intestine
COSM4949470	c.3276T>A	p.A1092A	Substitution - coding silent	Liver
COSM5809894	c.4015C>T	p.Q1339*	Substitution - Nonsense	Liver
COSM4799656	c.4923-2A>G	p.?	Unknown	Liver
COSM5551578	c.4055A>G	p.D1352G	Substitution - Missense	Prostate
COSM5046254	c.2390C>T	p.P797L	Substitution - Missense	Oesophagus
COSM5346292	c.602C>A	p.T201N	Substitution - Missense	Urinary_tract
COSM431131	c.4304C>T	p.S1435L	Substitution - Missense	Breast
COSM3704149	c.4888C>T	p.Q1630*	Substitution - Nonsense	Liver
COSM4767425	c.3841G>T	p.G1281W	Substitution - Missense	Biliary_tract
COSM3460986	c.5062G>A	p.D1688N	Substitution - Missense	Skin
COSM939489	c.211G>T	p.E71*	Substitution - Nonsense	Endometrium
COSM3704144	c.961C>T	p.H321Y	Substitution - Missense	Liver
COSM278971	c.940C>T	p.R314C	Substitution - Missense	Skin
COSM1167991	c.890C>T	p.S297F	Substitution - Missense	Skin
COSM1128591	c.2037A>T	p.Q679H	Substitution - Missense	Prostate
COSM4041997	c.4923-1G>C	p.?	Unknown	Stomach
COSM3954777	c.400C>T	p.Q134*	Substitution - Nonsense	Skin
COSM131489	c.2947C>T	p.Q983*	Substitution - Nonsense	Liver
COSM4041998	c.4999T>C	p.C1667R	Substitution - Missense	Stomach
COSM4334453	c.103delA	p.I37fs*21	Deletion - Frameshift	Large_intestine
COSM3460978	c.4150C>T	p.H1384Y	Substitution - Missense	Skin
COSM5548899	c.5318C>T	p.A1773V	Substitution - Missense	Prostate
COSM265253	c.854G>A	p.R285Q	Substitution - Missense	Breast
COSM268370	c.4651G>A	p.A1551T	Substitution - Missense	Large_intestine
COSM36756	c.4061G>A	p.R1354K	Substitution - Missense	Skin
COSM1167907	c.5147+1G>A	p.?	Unknown	Large_intestine
COSM4767425	c.3841G>T	p.G1281W	Substitution - Missense	Biliary_tract
COSM1512174	c.820C>T	p.R274*	Substitution - Nonsense	Skin
COSM1167991	c.890C>T	p.S297F	Substitution - Missense	Skin
COSM1628606	c.1120G>C	p.G374R	Substitution - Missense	Liver
COSM1676889	c.1006G>T	p.G336*	Substitution - Nonsense	Large_intestine
COSM1676889	c.1006G>T	p.G336*	Substitution - Nonsense	Large_intestine
COSM4041977	c.161T>C	p.V54A	Substitution - Missense	Stomach
COSM5953323	c.487C>T	p.L163F	Substitution - Missense	Oesophagus
COSM5733535	c.989T>G	p.L330*	Substitution - Nonsense	Pancreas
COSM431133	c.5199T>G	p.I1733M	Substitution - Missense	Breast
COSM5348731	c.2892_2893insACA	p.G964_Q965insT	Insertion - In frame	Liver
COSM4887334	c.4603G>T	p.G1535*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM5490569	c.3040C>T	p.Q1014*	Substitution - Nonsense	Biliary_tract
COSM3812048	c.1561G>A	p.E521K	Substitution - Missense	Breast
COSM131036	c.4753_4756delGTAC	p.V1585fs*40	Deletion - Frameshift	Liver
COSM1159017	c.2815_2816insA	p.Y939fs*1	Insertion - Frameshift	Pancreas
COSM1628616	c.5305C>T	p.R1769*	Substitution - Nonsense	Liver
COSM3416862	c.587A>C	p.D196A	Substitution - Missense	Large_intestine
COSM268370	c.4651G>A	p.A1551T	Substitution - Missense	Large_intestine
COSM939511	c.4143T>G	p.T1381T	Substitution - coding silent	Endometrium
COSM1512174	c.820C>T	p.R274*	Substitution - Nonsense	Biliary_tract
COSM1318014	c.193G>T	p.E65*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM278971	c.940C>T	p.R314C	Substitution - Missense	Skin
COSM358685	c.2776G>T	p.V926L	Substitution - Missense	Lung
COSM1245451	c.3965delT	p.I1322fs*9	Deletion - Frameshift	Oesophagus
COSM5019142	c.4815C>T	p.G1605G	Substitution - coding silent	Soft_tissue
COSM3986925	c.2977A>T	p.T993S	Substitution - Missense	Kidney
COSM1361681	c.875delT	p.L293fs*1	Deletion - Frameshift	Large_intestine
COSM1628602	c.551C>G	p.S184*	Substitution - Nonsense	Liver
COSM2067836	c.2802A>G	p.Q934Q	Substitution - coding silent	Large_intestine
COSM1746979	c.2337A>T	p.V779V	Substitution - coding silent	Urinary_tract
COSM939507	c.3352C>T	p.Q1118*	Substitution - Nonsense	Endometrium
COSM251395	c.1716-2A>G	p.?	Unknown	Liver
COSM5990679	c.1856C>T	p.T619I	Substitution - Missense	Liver
COSM268708	c.3952C>T	p.Q1318*	Substitution - Nonsense	Large_intestine
COSM1361684	c.1331-1G>A	p.?	Unknown	Large_intestine
COSM4575400	c.4146C>T	p.S1382S	Substitution - coding silent	Bone
COSM2067812	c.1592A>G	p.H531R	Substitution - Missense	Upper_aerodigestive_tract
COSM251412	c.1073C>G	p.T358S	Substitution - Missense	Liver
COSM4950827	c.2992G>A	p.G998R	Substitution - Missense	Liver
COSM5607879	c.3196C>T	p.P1066S	Substitution - Missense	Skin
COSM1167951	c.2611C>T	p.Q871*	Substitution - Nonsense	Skin
COSM5640852	c.4005A>G	p.A1335A	Substitution - coding silent	Oesophagus
COSM939507	c.3352C>T	p.Q1118*	Substitution - Nonsense	Skin
COSM5624231	c.1719G>A	p.T573T	Substitution - coding silent	Oesophagus
COSM1168000	c.3396T>G	p.S1132R	Substitution - Missense	Skin
COSM4593385	c.4663G>T	p.A1555S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5878502	c.1418C>T	p.S473F	Substitution - Missense	Liver
COSM3460982	c.4685C>T	p.P1562L	Substitution - Missense	Skin
COSM265253	c.854G>A	p.R285Q	Substitution - Missense	Pancreas
COSM939504	c.2591C>T	p.A864V	Substitution - Missense	Endometrium
COSM1628616	c.5305C>T	p.R1769*	Substitution - Nonsense	Skin
COSM1606141	c.3817C>T	p.R1273*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM1628611	c.4613delT	p.I1538fs*28	Deletion - Frameshift	Liver
COSM1245455	c.1264C>A	p.L422I	Substitution - Missense	Stomach
COSM3700280	c.1951C>T	p.Q651*	Substitution - Nonsense	Liver
COSM4663265	c.479A>G	p.K160R	Substitution - Missense	Large_intestine
COSM1167994	c.2128C>T	p.P710S	Substitution - Missense	Skin
COSM939498	c.1344T>C	p.C448C	Substitution - coding silent	Endometrium
COSM4575399	c.121G>C	p.G41R	Substitution - Missense	Bone
COSM4829498	c.3926C>G	p.S1309*	Substitution - Nonsense	Cervix
COSM1361680	c.649delT	p.S218fs*74	Deletion - Frameshift	Large_intestine
COSM3792598	c.3528T>C	p.V1176V	Substitution - coding silent	Urinary_tract
COSM355008	c.4003G>T	p.A1335S	Substitution - Missense	Lung
COSM5041485	c.1023+2T>G	p.?	Unknown	Liver
COSM318772	c.220G>T	p.E74*	Substitution - Nonsense	Liver
COSM1628614	c.5260C>T	p.R1754*	Substitution - Nonsense	Liver
COSM166441	c.4909C>T	p.Q1637*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM251395	c.1716-2A>G	p.?	Unknown	Liver
COSM5882252	c.3049C>T	p.H1017Y	Substitution - Missense	Skin
COSM391816	c.2983_2984insA	p.S996fs*61	Insertion - Frameshift	Lung
COSM5024820	c.3568G>T	p.G1190*	Substitution - Nonsense	Large_intestine
COSM3724480	c.1517C>T	p.A506V	Substitution - Missense	Large_intestine
COSM218404	c.940C>A	p.R314S	Substitution - Missense	Pancreas
COSM4399765	c.1468C>T	p.Q490*	Substitution - Nonsense	Skin
COSM1731244	c.4000G>T	p.G1334*	Substitution - Nonsense	Liver
COSM3384359	c.3102A>G	p.Q1034Q	Substitution - coding silent	Pancreas
COSM5473391	c.3334C>T	p.Q1112*	Substitution - Nonsense	Large_intestine
COSM4485215	c.2909C>T	p.P970L	Substitution - Missense	Skin
COSM3359734	c.899A>T	p.E300V	Substitution - Missense	Kidney
COSM251411	c.5174C>G	p.S1725*	Substitution - Nonsense	Liver
COSM1606133	c.1037C>T	p.P346L	Substitution - Missense	Liver
COSM5494555	c.5356_5363+1delGGTCGCAGG	p.?	Unknown	Biliary_tract
COSM5451260	c.1307T>A	p.I436N	Substitution - Missense	Large_intestine
COSM251412	c.1073C>G	p.T358S	Substitution - Missense	Liver
COSM4593385	c.4663G>T	p.A1555S	Substitution - Missense	Upper_aerodigestive_tract
COSM4891346	c.3818G>A	p.R1273Q	Substitution - Missense	Upper_aerodigestive_tract
COSM1361700	c.3438G>A	p.S1146S	Substitution - coding silent	Large_intestine
COSM4041984	c.721G>A	p.V241I	Substitution - Missense	Stomach
COSM1168752	c.2814_2815insA	p.Y939fs*12	Insertion - Frameshift	Pancreas
COSM3460969	c.2173C>T	p.Q725*	Substitution - Nonsense	Pancreas
COSM3968226	c.1126G>A	p.E376K	Substitution - Missense	Central_nervous_system
COSM4595925	c.3559G>A	p.V1187M	Substitution - Missense	Upper_aerodigestive_tract
COSM1245457	c.3025G>A	p.V1009M	Substitution - Missense	Oesophagus
COSM1159250	c.1716-1G>A	p.?	Unknown	Pancreas
COSM5048545	c.580G>C	p.E194Q	Substitution - Missense	Oesophagus
COSM5551912	c.728A>G	p.D243G	Substitution - Missense	Prostate
COSM1628606	c.1120G>C	p.G374R	Substitution - Missense	Skin
COSM4990226	c.1562A>C	p.E521A	Substitution - Missense	Skin
COSM693906	c.2101A>T	p.T701S	Substitution - Missense	Lung
COSM1512174	c.820C>T	p.R274*	Substitution - Nonsense	Skin
COSM278971	c.940C>T	p.R314C	Substitution - Missense	Skin
COSM278971	c.940C>T	p.R314C	Substitution - Missense	Skin
COSM5375175	c.1648C>T	p.L550F	Substitution - Missense	Skin
COSM5789495	c.2921C>T	p.P974L	Substitution - Missense	Breast
COSM3460970	c.2761C>T	p.P921S	Substitution - Missense	Skin
COSM1322501	c.3817C>A	p.R1273R	Substitution - coding silent	Ovary
COSM693898	c.4591C>T	p.P1531S	Substitution - Missense	Lung
COSM4767428	c.310C>A	p.H104N	Substitution - Missense	Biliary_tract
COSM939524	c.4993G>T	p.G1665W	Substitution - Missense	Endometrium
COSM1645192	c.2543_2544insT	p.A849fs*102	Insertion - Frameshift	Liver
COSM1606142	c.3844G>C	p.D1282H	Substitution - Missense	Liver
COSM4997839	c.2722_2731del10	p.S908fs*16	Deletion - Frameshift	Pancreas
COSM1476565	c.1653G>A	p.S551S	Substitution - coding silent	Large_intestine
COSM1705490	c.1672C>T	p.R558C	Substitution - Missense	Skin
COSM3460973	c.2952C>T	p.V984V	Substitution - coding silent	Skin
COSM5451260	c.1307T>A	p.I436N	Substitution - Missense	Large_intestine
COSM3812050	c.3931A>G	p.K1311E	Substitution - Missense	Breast
COSM468375	c.678A>G	p.K226K	Substitution - coding silent	Kidney
COSM271715	c.1552_1555delATAG	p.D519fs*9	Deletion - Frameshift	Large_intestine
COSM939501	c.1867C>T	p.R623C	Substitution - Missense	Endometrium
COSM3710884	c.2110C>T	p.Q704*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM3368819	c.3091C>T	p.Q1031*	Substitution - Nonsense	Thyroid
COSM5413317	c.2350C>T	p.P784S	Substitution - Missense	Skin
COSM1705492	c.4459C>A	p.P1487T	Substitution - Missense	Skin
COSM318773	c.5183G>C	p.R1728T	Substitution - Missense	Lung
COSM5809471	c.1121-2A>G	p.?	Unknown	Liver
COSM5607882	c.3023C>T	p.S1008F	Substitution - Missense	Skin
COSM5361289	c.2607delT	p.Q871fs*2	Deletion - Frameshift	Large_intestine
COSM1238223	c.1787T>C	p.V596A	Substitution - Missense	Oesophagus
COSM939508	c.3482C>T	p.A1161V	Substitution - Missense	Endometrium
COSM1686177	c.2239C>T	p.H747Y	Substitution - Missense	Skin
COSM1159250	c.1716-1G>A	p.?	Unknown	Large_intestine
COSM4888189	c.5397G>T	p.V1799V	Substitution - coding silent	Upper_aerodigestive_tract
COSM939497	c.1169T>A	p.L390*	Substitution - Nonsense	Endometrium
COSM1299386	c.5203A>T	p.N1735Y	Substitution - Missense	Urinary_tract
COSM3724479	c.73C>T	p.Q25*	Substitution - Nonsense	Large_intestine
COSM1167929	c.2872C>T	p.Q958*	Substitution - Nonsense	Skin
COSM5725619	c.992G>A	p.G331D	Substitution - Missense	Skin
COSM1361702	c.3806C>T	p.P1269L	Substitution - Missense	Oesophagus
COSM2067871	c.4819C>T	p.P1607S	Substitution - Missense	Large_intestine
COSM1676889	c.1006G>T	p.G336*	Substitution - Nonsense	Large_intestine
COSM1245454	c.1624C>T	p.R542*	Substitution - Nonsense	Oesophagus
COSM3710883	c.723T>C	p.V241V	Substitution - coding silent	Upper_aerodigestive_tract
COSM3384361	c.4207C>T	p.Q1403*	Substitution - Nonsense	Pancreas
COSM693899	c.4391G>A	p.R1464H	Substitution - Missense	Lung
COSM4990225	c.797G>A	p.W266*	Substitution - Nonsense	Skin
COSM1606144	c.4427C>T	p.S1476F	Substitution - Missense	Liver
COSM5361621	c.246T>C	p.C82C	Substitution - coding silent	Large_intestine
COSM459508	c.595A>G	p.I199V	Substitution - Missense	Cervix
COSM3460977	c.4096A>T	p.K1366*	Substitution - Nonsense	Skin
COSM4950827	c.2992G>A	p.G998R	Substitution - Missense	Liver
COSM5702939	c.3985G>A	p.E1329K	Substitution - Missense	Autonomic_ganglia
COSM3968227	c.1135G>C	p.G379R	Substitution - Missense	Central_nervous_system
COSM1746977	c.103A>T	p.K35*	Substitution - Nonsense	Urinary_tract
COSM3704145	c.1691C>T	p.S564L	Substitution - Missense	Liver
COSM1183567	c.2495C>A	p.S832*	Substitution - Nonsense	Large_intestine
COSM5794111	c.3500C>T	p.T1167I	Substitution - Missense	Breast
COSM939494	c.586G>T	p.D196Y	Substitution - Missense	Breast
COSM1606132	c.953delT	p.S319fs*9	Deletion - Frameshift	Liver
COSM4777221	c.733G>T	p.E245*	Substitution - Nonsense	Breast
COSM5473390	c.2775C>T	p.S925S	Substitution - coding silent	Large_intestine
COSM1167991	c.890C>T	p.S297F	Substitution - Missense	Skin
COSM5704455	c.5046_5047delTA	p.I1683fs*6	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM5922947	c.3161C>T	p.S1054F	Substitution - Missense	Skin
COSM5348620	c.4609_4610insA	p.R1537fs*7	Insertion - Frameshift	Liver
COSM5611229	c.294_295AA>TT	p.E98_K99>D*	Complex - compound substitution	Skin
COSM3700281	c.5435C>G	p.A1812G	Substitution - Missense	Liver
COSM5346261	c.594A>T	p.K198N	Substitution - Missense	Urinary_tract
COSM1167991	c.890C>T	p.S297F	Substitution - Missense	Skin
COSM1746978	c.1062G>A	p.L354L	Substitution - coding silent	Urinary_tract
COSM6008924	c.847G>A	p.G283R	Substitution - Missense	Large_intestine
COSM5346433	c.597C>T	p.I199I	Substitution - coding silent	Urinary_tract
COSM1245453	c.2500C>T	p.Q834*	Substitution - Nonsense	Oesophagus
COSM939506	c.2969C>T	p.S990L	Substitution - Missense	Skin
COSM4663272	c.3831C>T	p.N1277N	Substitution - coding silent	Large_intestine
COSM4152822	c.1308T>A	p.I436I	Substitution - coding silent	Kidney
COSM4593385	c.4663G>T	p.A1555S	Substitution - Missense	Upper_aerodigestive_tract
COSM231543	c.2872_2873insA	p.T959fs*9	Insertion - Frameshift	Skin
COSM939503	c.2220G>C	p.Q740H	Substitution - Missense	Endometrium
COSM318772	c.220G>T	p.E74*	Substitution - Nonsense	Liver
COSM218404	c.940C>A	p.R314S	Substitution - Missense	Pancreas
COSM3460988	c.5431C>T	p.L1811F	Substitution - Missense	Skin
COSM4593385	c.4663G>T	p.A1555S	Substitution - Missense	Upper_aerodigestive_tract
COSM5724968	c.4795C>T	p.P1599S	Substitution - Missense	Skin
COSM1606147	c.4878delA	p.K1627fs*74	Deletion - Frameshift	Liver
COSM5494554	c.1985_1986insTT	p.T663fs*1	Insertion - Frameshift	Biliary_tract
COSM939510	c.4052G>T	p.S1351I	Substitution - Missense	Endometrium
COSM1299385	c.3617C>T	p.T1206M	Substitution - Missense	Urinary_tract
COSM217018	c.2134G>T	p.E712*	Substitution - Nonsense	Liver
COSM1606144	c.4427C>T	p.S1476F	Substitution - Missense	Liver
COSM5348215	c.867delT	p.I289fs*3	Deletion - Frameshift	Liver
COSM5490587	c.1580+1G>T	p.?	Unknown	Biliary_tract
COSM4822928	c.5230C>A	p.L1744M	Substitution - Missense	Cervix
COSM939511	c.4143T>G	p.T1381T	Substitution - coding silent	Stomach
COSM2067865	c.4384C>T	p.Q1462*	Substitution - Nonsense	Biliary_tract
COSM939528	c.5487A>C	p.K1829N	Substitution - Missense	Endometrium
COSM1361700	c.3438G>A	p.S1146S	Substitution - coding silent	Stomach
COSM5346260	c.593A>T	p.K198I	Substitution - Missense	Urinary_tract
COSM5734841	c.76delT	p.F26fs*32	Deletion - Frameshift	Pancreas
COSM3871643	c.3778G>T	p.E1260*	Substitution - Nonsense	Skin
COSM1159250	c.1716-1G>A	p.?	Unknown	Pancreas
COSM4593385	c.4663G>T	p.A1555S	Substitution - Missense	Upper_aerodigestive_tract
COSM3871641	c.1972C>T	p.Q658*	Substitution - Nonsense	Skin
COSM5620310	c.3033G>T	p.R1011S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3720868	c.1419C>T	p.S473S	Substitution - coding silent	Upper_aerodigestive_tract
COSM278971	c.940C>T	p.R314C	Substitution - Missense	Skin
COSM328673	c.1607_1608delCA	p.P536fs*12	Deletion - Frameshift	Liver
COSM3724483	c.4111C>T	p.H1371Y	Substitution - Missense	Large_intestine
COSM3812049	c.3877C>A	p.L1293I	Substitution - Missense	Breast
COSM5724968	c.4795C>T	p.P1599S	Substitution - Missense	Skin
COSM251395	c.1716-2A>G	p.?	Unknown	Liver
COSM1167994	c.2128C>T	p.P710S	Substitution - Missense	Skin
COSM431129	c.3953_3954insG	p.C1319fs*6	Insertion - Frameshift	Breast
COSM98118	c.2710C>T	p.Q904*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM73729	c.3496G>C	p.G1166R	Substitution - Missense	Ovary
COSM957512	c.772_772+20del21	p.?	Unknown	Lung
COSM1245454	c.1624C>T	p.R542*	Substitution - Nonsense	Skin
COSM147485	c.285T>C	p.R95R	Substitution - coding silent	Stomach
COSM4423034	c.1715G>T	p.R572I	Substitution - Missense	Central_nervous_system
COSM4166788	c.3540G>A	p.T1180T	Substitution - coding silent	Pituitary
COSM3704150	c.5188C>T	p.Q1730*	Substitution - Nonsense	Liver
COSM159179	c.4858C>T	p.Q1620*	Substitution - Nonsense	Breast
COSM1562099	c.15G>A	p.T5T	Substitution - coding silent	Large_intestine
COSM3368818	c.222A>G	p.E74E	Substitution - coding silent	Thyroid
COSM4136197	c.1024-2A>C	p.?	Unknown	Pancreas
COSM4421146	c.1979C>A	p.S660*	Substitution - Nonsense	Pleura
COSM5945893	c.3217C>G	p.P1073A	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3460987	c.5380G>T	p.E1794*	Substitution - Nonsense	Skin
COSM5413318	c.2879T>C	p.V960A	Substitution - Missense	Skin
COSM278971	c.940C>T	p.R314C	Substitution - Missense	Skin
COSM4041985	c.928C>T	p.R310C	Substitution - Missense	Stomach
COSM4041990	c.3149G>C	p.G1050A	Substitution - Missense	Stomach
COSM3724482	c.3065_3065delC	p.P1022fs*38	Deletion - Frameshift	Large_intestine
COSM1361688	c.1616C>A	p.S539Y	Substitution - Missense	Large_intestine
COSM693900	c.3629T>C	p.V1210A	Substitution - Missense	Lung
COSM3704144	c.961C>T	p.H321Y	Substitution - Missense	Liver
COSM1628614	c.5260C>T	p.R1754*	Substitution - Nonsense	Liver
COSM1606131	c.799G>T	p.E267*	Substitution - Nonsense	Biliary_tract
COSM4966894	c.60G>A	p.L20L	Substitution - coding silent	Prostate
COSM5375177	c.3964A>T	p.I1322F	Substitution - Missense	Skin
COSM3780983	c.1405G>T	p.E469*	Substitution - Nonsense	Pancreas
COSM1240860	c.205_206insG	p.E71fs*4	Insertion - Frameshift	Oesophagus
COSM5990676	c.1073C>T	p.T358I	Substitution - Missense	Liver
COSM5413320	c.4252G>T	p.G1418*	Substitution - Nonsense	Skin
COSM243050	c.939T>A	p.L313L	Substitution - coding silent	Prostate
COSM957508	c.4270G>T	p.G1424C	Substitution - Missense	Lung
COSM4496809	c.4831C>T	p.Q1611*	Substitution - Nonsense	Skin
COSM4747147	c.3256delC	p.P1087fs*69	Deletion - Frameshift	Stomach
COSM5970702	c.5232G>C	p.L1744L	Substitution - coding silent	Upper_aerodigestive_tract
COSM278971	c.940C>T	p.R314C	Substitution - Missense	Large_intestine
COSM159177	c.3859G>A	p.E1287K	Substitution - Missense	Breast
COSM1167991	c.890C>T	p.S297F	Substitution - Missense	Skin
COSM4041992	c.3814C>T	p.R1272*	Substitution - Nonsense	Stomach
COSM4829488	c.4174C>G	p.P1392A	Substitution - Missense	Cervix
COSM4951170	c.3543_3544insT	p.A1183fs*58	Insertion - Frameshift	Liver
COSM1183568	c.4196T>G	p.L1399*	Substitution - Nonsense	Large_intestine
COSM2067795	c.994C>T	p.L332F	Substitution - Missense	Skin
COSM1167991	c.890C>T	p.S297F	Substitution - Missense	Skin
COSM131488	c.1177G>T	p.E393*	Substitution - Nonsense	Liver
COSM5794302	c.1115T>C	p.M372T	Substitution - Missense	Breast
COSM5985331	c.4565C>G	p.T1522S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM431130	c.4022C>G	p.S1341*	Substitution - Nonsense	Breast
COSM2156322	c.4016_4017delAG	p.N1340fs*12	Deletion - Frameshift	Central_nervous_system
COSM4593385	c.4663G>T	p.A1555S	Substitution - Missense	Upper_aerodigestive_tract
COSM307378	c.4720G>T	p.V1574F	Substitution - Missense	Kidney
COSM5704452	c.271C>T	p.Q91*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM278971	c.940C>T	p.R314C	Substitution - Missense	Skin
COSM693914	c.155C>T	p.T52I	Substitution - Missense	Breast
COSM5946922	c.2187T>C	p.P729P	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM468376	c.3795C>A	p.V1265V	Substitution - coding silent	Kidney
COSM4950102	c.2717_2718insT	p.S907fs*44	Insertion - Frameshift	Liver
COSM69715	c.740G>A	p.R247H	Substitution - Missense	Ovary
COSM1606150	c.5110G>T	p.E1704*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM278971	c.940C>T	p.R314C	Substitution - Missense	Skin
COSM3739671	c.2877A>T	p.T959T	Substitution - coding silent	Liver
COSM1512173	c.1426C>T	p.Q476*	Substitution - Nonsense	Biliary_tract
COSM358686	c.3734A>G	p.Q1245R	Substitution - Missense	Lung
COSM693911	c.493C>T	p.L165L	Substitution - coding silent	Lung
COSM5990078	c.914delT	p.L305fs*23	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM77289	c.2296C>T	p.P766S	Substitution - Missense	Ovary
COSM131488	c.1177G>T	p.E393*	Substitution - Nonsense	Liver
COSM1361700	c.3438G>A	p.S1146S	Substitution - coding silent	Skin
COSM939514	c.4582G>A	p.A1528T	Substitution - Missense	Endometrium
COSM5790170	c.265T>A	p.L89I	Substitution - Missense	Breast
COSM3704147	c.3648G>A	p.T1216T	Substitution - coding silent	Liver
COSM3460959	c.284+1G>A	p.?	Unknown	Skin
COSM1183572	c.881G>T	p.R294I	Substitution - Missense	Skin
COSM306815	c.4573_4576GAAA>GAA	p.E1525fs	Complex	Central_nervous_system
COSM1734595	c.1259A>T	p.E420V	Substitution - Missense	Pancreas
COSM318772	c.220G>T	p.E74*	Substitution - Nonsense	Lung
COSM939505	c.2740C>T	p.P914S	Substitution - Missense	Endometrium
COSM166441	c.4909C>T	p.Q1637*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM107635	c.3127C>T	p.Q1043*	Substitution - Nonsense	Skin
COSM5347579	c.1576_1580+2delCAGTGGT	p.?	Unknown	Liver
COSM1167993	c.3937C>T	p.Q1313*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM4496809	c.4831C>T	p.Q1611*	Substitution - Nonsense	Biliary_tract
COSM5811635	c.5343A>G	p.K1781K	Substitution - coding silent	Liver
COSM251411	c.5174C>G	p.S1725*	Substitution - Nonsense	Liver
COSM939506	c.2969C>T	p.S990L	Substitution - Missense	Biliary_tract
COSM4420879	c.5459T>G	p.F1820C	Substitution - Missense	Prostate
COSM4888553	c.1186G>C	p.D396H	Substitution - Missense	Upper_aerodigestive_tract
COSM4633663	c.478A>G	p.K160E	Substitution - Missense	Large_intestine
COSM1167955	c.2680C>T	p.Q894*	Substitution - Nonsense	Skin
COSM159177	c.3859G>A	p.E1287K	Substitution - Missense	Salivary_gland
COSM1628610	c.1928C>A	p.S643*	Substitution - Nonsense	Liver
COSM957511	c.3985G>T	p.E1329*	Substitution - Nonsense	Lung
COSM4041986	c.1100A>T	p.D367V	Substitution - Missense	Stomach
COSM3704145	c.1691C>T	p.S564L	Substitution - Missense	Liver
COSM5413317	c.2350C>T	p.P784S	Substitution - Missense	Skin
COSM1512173	c.1426C>T	p.Q476*	Substitution - Nonsense	Skin
COSM4949469	c.3277C>T	p.P1093S	Substitution - Missense	Liver
COSM4041983	c.716A>T	p.D239V	Substitution - Missense	Stomach
COSM1361696	c.3201A>G	p.K1067K	Substitution - coding silent	Large_intestine
COSM131489	c.2947C>T	p.Q983*	Substitution - Nonsense	Biliary_tract
COSM939493	c.371T>G	p.I124S	Substitution - Missense	Endometrium
COSM5584491	c.3916C>T	p.P1306S	Substitution - Missense	Skin
COSM3460975	c.3536A>T	p.N1179I	Substitution - Missense	Skin
COSM3665404	c.4398_4416del19	p.V1467fs*12	Deletion - Frameshift	Liver
COSM1245456	c.2110C>G	p.Q704E	Substitution - Missense	Stomach
COSM939500	c.1638T>G	p.Y546*	Substitution - Nonsense	Endometrium
COSM5051595	c.2170delC	p.Q725fs*33	Deletion - Frameshift	Stomach
COSM693898	c.4591C>T	p.P1531S	Substitution - Missense	Skin
COSM1676888	c.551C>A	p.S184*	Substitution - Nonsense	Large_intestine
COSM5607877	c.4079G>A	p.G1360E	Substitution - Missense	Skin
COSM131488	c.1177G>T	p.E393*	Substitution - Nonsense	Lung
COSM4949785	c.1574_1580delGTCAGTG	p.Q526fs*1	Deletion - Frameshift	Liver
COSM5584491	c.3916C>T	p.P1306S	Substitution - Missense	Skin
COSM5548899	c.5318C>T	p.A1773V	Substitution - Missense	Prostate
COSM117869	c.3430C>T	p.P1144S	Substitution - Missense	Ovary
COSM4487595	c.3208C>T	p.P1070S	Substitution - Missense	Skin
COSM1686178	c.4039C>T	p.Q1347*	Substitution - Nonsense	Skin
COSM5451260	c.1307T>A	p.I436N	Substitution - Missense	Large_intestine
COSM3460976	c.3580C>T	p.Q1194*	Substitution - Nonsense	Skin
COSM4449807	c.3374delA	p.N1126fs*30	Deletion - Frameshift	Skin
COSM5762135	c.1580+1G>A	p.?	Unknown	Pancreas
COSM265253	c.854G>A	p.R285Q	Substitution - Missense	Skin
COSM693905	c.2250G>T	p.G750G	Substitution - coding silent	Lung
COSM4041987	c.1189C>T	p.Q397*	Substitution - Nonsense	Stomach
COSM4663271	c.3453G>A	p.L1151L	Substitution - coding silent	Large_intestine
COSM265253	c.854G>A	p.R285Q	Substitution - Missense	Large_intestine
COSM4747142	c.527_546del20	p.N178fs*2	Deletion - Frameshift	Stomach
COSM1666113	c.5237G>A	p.R1746K	Substitution - Missense	Eye
COSM4951261	c.1080_1081insA	p.C362fs*7	Insertion - Frameshift	Liver
COSM3460962	c.699C>T	p.F233F	Substitution - coding silent	Stomach
COSM251412	c.1073C>G	p.T358S	Substitution - Missense	Liver
COSM5966153	c.2764A>G	p.T922A	Substitution - Missense	Adrenal_gland
COSM5346770	c.596T>C	p.I199T	Substitution - Missense	Urinary_tract
COSM251369	c.1507_1508insAG	p.A503fs*4	Insertion - Frameshift	Liver
COSM265253	c.854G>A	p.R285Q	Substitution - Missense	Large_intestine
COSM4041981	c.535G>A	p.V179I	Substitution - Missense	Stomach
COSM1705491	c.3298C>T	p.Q1100*	Substitution - Nonsense	Liver
COSM4041982	c.620C>T	p.A207V	Substitution - Missense	Stomach
COSM1628617	c.5328delA	p.N1778fs*13	Deletion - Frameshift	Liver
COSM1167993	c.3937C>T	p.Q1313*	Substitution - Nonsense	Skin
COSM1628608	c.1298G>T	p.C433F	Substitution - Missense	Liver
COSM3460963	c.811C>T	p.H271Y	Substitution - Missense	Skin
COSM1628614	c.5260C>T	p.R1754*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM1727114	c.1837C>T	p.Q613*	Substitution - Nonsense	Liver
COSM3724481	c.5333_5333delA	p.N1778fs*13	Deletion - Frameshift	Large_intestine
COSM2067837	c.2809C>T	p.Q937*	Substitution - Nonsense	Biliary_tract
COSM1606146	c.4508delT	p.R1504fs*12	Deletion - Frameshift	Liver
COSM1628604	c.1056T>C	p.T352T	Substitution - coding silent	Liver
COSM1606135	c.1231G>T	p.D411Y	Substitution - Missense	Liver
COSM4824190	c.1250C>T	p.S417L	Substitution - Missense	Cervix
COSM3416865	c.4241G>T	p.R1414I	Substitution - Missense	Large_intestine
COSM1606140	c.3474delT	p.N1158fs*15	Deletion - Frameshift	Liver
COSM5952473	c.5029C>T	p.R1677*	Substitution - Nonsense	Oesophagus
COSM3718750	c.2169_2170insC	p.Q725fs*7	Insertion - Frameshift	Upper_aerodigestive_tract
COSM3460974	c.3121C>T	p.Q1041*	Substitution - Nonsense	Skin
COSM3935951	c.4644C>T	p.G1548G	Substitution - coding silent	Oesophagus
COSM5027578	c.2224_2225delTC	p.S742fs*6	Deletion - Frameshift	Breast
COSM3460967	c.1825C>T	p.Q609*	Substitution - Nonsense	Skin
COSM2067851	c.3470C>T	p.S1157L	Substitution - Missense	Skin
COSM1606149	c.5001T>G	p.C1667W	Substitution - Missense	Liver
COSM5548899	c.5318C>T	p.A1773V	Substitution - Missense	Prostate
COSM1606142	c.3844G>C	p.D1282H	Substitution - Missense	Liver
COSM266035	c.925A>G	p.N309D	Substitution - Missense	Large_intestine
COSM1746977	c.103A>T	p.K35*	Substitution - Nonsense	Urinary_tract
COSM1606138	c.2865delA	p.A956fs*7	Deletion - Frameshift	Liver
COSM1606141	c.3817C>T	p.R1273*	Substitution - Nonsense	Liver
COSM1183570	c.1330G>T	p.D444Y	Substitution - Missense	Large_intestine
COSM1167993	c.3937C>T	p.Q1313*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM1705491	c.3298C>T	p.Q1100*	Substitution - Nonsense	Liver
COSM693907	c.1868G>T	p.R623L	Substitution - Missense	Lung
COSM4754287	c.1337T>A	p.L446*	Substitution - Nonsense	Stomach
COSM939489	c.211G>T	p.E71*	Substitution - Nonsense	Large_intestine
COSM1685690	c.4463_4475del13	p.D1488fs*24	Deletion - Frameshift	Skin
COSM5985330	c.2939C>G	p.T980S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM251395	c.1716-2A>G	p.?	Unknown	Liver
COSM265477	c.520G>T	p.D174Y	Substitution - Missense	Large_intestine
COSM348671	c.706-1G>T	p.?	Unknown	Lung
COSM1245452	c.102_103insA	p.I37fs*29	Insertion - Frameshift	Oesophagus
COSM1606141	c.3817C>T	p.R1273*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM290981	c.3612C>T	p.S1204S	Substitution - coding silent	Large_intestine
COSM1183572	c.881G>T	p.R294I	Substitution - Missense	Skin
COSM1361695	c.2864C>T	p.P955L	Substitution - Missense	Large_intestine
COSM1167991	c.890C>T	p.S297F	Substitution - Missense	Skin
COSM189021	c.853C>T	p.R285W	Substitution - Missense	Pancreas
COSM1606131	c.799G>T	p.E267*	Substitution - Nonsense	Liver
COSM3460972	c.2890G>T	p.G964*	Substitution - Nonsense	Skin
COSM5990678	c.1519C>T	p.Q507*	Substitution - Nonsense	Liver
COSM5414588	c.739C>T	p.R247C	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM957510	c.3596C>T	p.A1199V	Substitution - Missense	Lung
COSM1167927	c.3493C>T	p.Q1165*	Substitution - Nonsense	Skin
COSM4771207	c.2086C>T	p.Q696*	Substitution - Nonsense	Pleura
COSM251424	c.1802G>A	p.R601Q	Substitution - Missense	Liver
COSM2067821	c.1900C>G	p.P634A	Substitution - Missense	Skin
COSM4949786	c.4031_4032ins68	p.I1344fs*5	Insertion - Frameshift	Liver
COSM3986926	c.3010A>T	p.S1004C	Substitution - Missense	Kidney
COSM693908	c.1561G>T	p.E521*	Substitution - Nonsense	Lung
COSM268707	c.521A>G	p.D174G	Substitution - Missense	Large_intestine
COSM5794111	c.3500C>T	p.T1167I	Substitution - Missense	Breast
COSM1361702	c.3806C>T	p.P1269L	Substitution - Missense	Large_intestine
COSM3359735	c.963T>C	p.H321H	Substitution - coding silent	Kidney
COSM5413321	c.5065A>T	p.K1689*	Substitution - Nonsense	Skin
COSM3384358	c.1715+5G>C	p.?	Unknown	Pancreas
COSM3416864	c.4068G>A	p.P1356P	Substitution - coding silent	Large_intestine
COSM4927869	c.1086T>C	p.C362C	Substitution - coding silent	Liver
COSM5347581	c.5391_5392delAT	p.L1797fs*6	Deletion - Frameshift	Liver
COSM3376252	c.588T>C	p.D196D	Substitution - coding silent	Pancreas
COSM106761	c.430C>T	p.Q144*	Substitution - Nonsense	Breast
COSM3416863	c.4017G>T	p.Q1339H	Substitution - Missense	Large_intestine
COSM5958890	c.1211delT	p.C405fs*11	Deletion - Frameshift	Thyroid
COSM131034	c.4065delA	p.K1355fs*3	Deletion - Frameshift	Liver
COSM306815	c.4573_4576GAAA>GAA	p.E1525fs	Complex	Central_nervous_system
COSM1705491	c.3298C>T	p.Q1100*	Substitution - Nonsense	Skin
COSM5039695	c.3458G>A	p.G1153D	Substitution - Missense	Liver
COSM3665403	c.2292_2313del22	p.H765fs*20	Deletion - Frameshift	Liver
COSM5878503	c.2324T>A	p.L775*	Substitution - Nonsense	Liver
COSM3460960	c.366T>G	p.L122L	Substitution - coding silent	Skin
COSM5346771	c.604T>C	p.L202L	Substitution - coding silent	Urinary_tract
COSM3368819	c.3091C>T	p.Q1031*	Substitution - Nonsense	Biliary_tract
COSM4990227	c.1581-1G>A	p.?	Unknown	Skin
COSM1676888	c.551C>A	p.S184*	Substitution - Nonsense	Large_intestine
COSM5980283	c.3389T>C	p.V1130A	Substitution - Missense	Upper_aerodigestive_tract
COSM1159250	c.1716-1G>A	p.?	Unknown	Pancreas
COSM6008926	c.3739G>C	p.E1247Q	Substitution - Missense	Large_intestine
COSM347002	c.700G>A	p.V234I	Substitution - Missense	Lung
COSM379857	c.1719G>T	p.T573T	Substitution - coding silent	Lung
COSM5985330	c.2939C>G	p.T980S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM139956	c.1499-1G>A	p.?	Unknown	Skin
COSM4663268	c.1795G>A	p.V599I	Substitution - Missense	Large_intestine
COSM6008962	c.3754G>T	p.E1252*	Substitution - Nonsense	Large_intestine
COSM1606150	c.5110G>T	p.E1704*	Substitution - Nonsense	Liver
COSM1167991	c.890C>T	p.S297F	Substitution - Missense	Skin
COSM1167930	c.1758C>T	p.S586S	Substitution - coding silent	Skin
COSM5964059	c.5062-7C>G	p.?	Unknown	Breast
COSM2067866	c.4390C>T	p.R1464C	Substitution - Missense	Stomach
COSM4041989	c.2649C>G	p.V883V	Substitution - coding silent	Stomach
COSM1361699	c.3319G>A	p.A1107T	Substitution - Missense	Large_intestine
COSM141377	c.5272-1G>A	p.?	Unknown	Upper_aerodigestive_tract
COSM4041999	c.5272-1G>T	p.?	Unknown	Stomach
COSM251383	c.3987_3988ins16	p.L1330fs*3	Insertion - Frameshift	Liver
COSM5951321	c.284+4_284+5insT	p.?	Unknown	Oesophagus
COSM5882251	c.3048A>T	p.Q1016H	Substitution - Missense	Skin
COSM189021	c.853C>T	p.R285W	Substitution - Missense	Large_intestine
COSM5878504	c.1084_1110del27	p.C362_L370delCLMSRDRFL	Deletion - In frame	Liver
COSM4951262	c.4169_4170insT	p.S1391fs*20	Insertion - Frameshift	Liver
COSM3460981	c.4509T>G	p.V1503V	Substitution - coding silent	Skin
COSM5346192	c.598A>C	p.I200L	Substitution - Missense	Urinary_tract
COSM1245458	c.3445C>T	p.Q1149*	Substitution - Nonsense	Oesophagus
COSM4444411	c.2681A>G	p.Q894R	Substitution - Missense	Large_intestine
COSM957513	c.1_5508del5508	p.0?	Whole gene deletion	Lung
COSM131032	c.2438delC	p.S813fs*9	Deletion - Frameshift	Liver
COSM217018	c.2134G>T	p.E712*	Substitution - Nonsense	Liver
COSM4829498	c.3926C>G	p.S1309*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM5878500	c.1120+5G>C	p.?	Unknown	Liver
COSM4951262	c.4169_4170insT	p.S1391fs*20	Insertion - Frameshift	Liver
COSM3398729	c.4043A>T	p.D1348V	Substitution - Missense	Central_nervous_system
COSM3704147	c.3648G>A	p.T1216T	Substitution - coding silent	Liver
COSM4041995	c.4511G>A	p.R1504Q	Substitution - Missense	Stomach
COSM5607881	c.3431C>T	p.P1144L	Substitution - Missense	Skin
COSM1606136	c.2392C>T	p.Q798*	Substitution - Nonsense	Liver
COSM1685689	c.1651delT	p.S551fs*6	Deletion - Frameshift	Skin
COSM957509	c.2833C>T	p.Q945*	Substitution - Nonsense	Lung
COSM1606148	c.4938C>T	p.P1646P	Substitution - coding silent	Liver
COSM3954777	c.400C>T	p.Q134*	Substitution - Nonsense	Lung
COSM1245454	c.1624C>T	p.R542*	Substitution - Nonsense	Central_nervous_system
COSM5413319	c.3492C>T	p.F1164F	Substitution - coding silent	Skin
COSM4747145	c.1201_1202delAG	p.E402fs*9	Deletion - Frameshift	Stomach
COSM1512174	c.820C>T	p.R274*	Substitution - Nonsense	Skin
COSM5607880	c.3912A>T	p.L1304L	Substitution - coding silent	Skin
COSM2067871	c.4819C>T	p.P1607S	Substitution - Missense	Large_intestine
COSM3871644	c.4487C>T	p.S1496F	Substitution - Missense	Skin
COSM3954778	c.2310A>T	p.P770P	Substitution - coding silent	Lung
COSM6008957	c.2377C>T	p.Q793*	Substitution - Nonsense	Large_intestine
COSM1606131	c.799G>T	p.E267*	Substitution - Nonsense	Liver
COSM1606145	c.4427_4428insT	p.V1477fs*26	Insertion - Frameshift	Liver
COSM4949469	c.3277C>T	p.P1093S	Substitution - Missense	Liver
COSM4921149	c.4245T>G	p.I1415M	Substitution - Missense	Liver
COSM4951169	c.5131C>T	p.Q1711*	Substitution - Nonsense	Liver
COSM4622623	c.966T>C	p.S322S	Substitution - coding silent	Large_intestine
COSM1167991	c.890C>T	p.S297F	Substitution - Missense	Skin
COSM1728784	c.1716-2A>T	p.?	Unknown	Liver
COSM328761	c.2902A>T	p.I968L	Substitution - Missense	Liver
COSM1628614	c.5260C>T	p.R1754*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM1746980	c.4531G>T	p.E1511*	Substitution - Nonsense	Urinary_tract
COSM1183569	c.4510C>T	p.R1504W	Substitution - Missense	Large_intestine
COSM4949470	c.3276T>A	p.A1092A	Substitution - coding silent	Liver
COSM4767424	c.1715+1G>A	p.?	Unknown	Biliary_tract
COSM1676890	c.2817T>G	p.Y939*	Substitution - Nonsense	Central_nervous_system
COSM3739669	c.1716-9A>G	p.?	Unknown	Liver
COSM1183572	c.881G>T	p.R294I	Substitution - Missense	Skin
COSM1167991	c.890C>T	p.S297F	Substitution - Missense	Skin
COSM3384360	c.3799G>T	p.E1267*	Substitution - Nonsense	Pancreas
COSM5640505	c.4258G>A	p.V1420I	Substitution - Missense	Oesophagus
COSM5640618	c.4675G>T	p.G1559*	Substitution - Nonsense	Oesophagus
COSM4754286	c.1142T>A	p.L381H	Substitution - Missense	Stomach
COSM2067869	c.4444C>T	p.Q1482*	Substitution - Nonsense	Stomach
COSM251411	c.5174C>G	p.S1725*	Substitution - Nonsense	Liver
COSM5607883	c.1209C>T	p.I403I	Substitution - coding silent	Skin
COSM5725619	c.992G>A	p.G331D	Substitution - Missense	Skin
COSM5913333	c.2009C>T	p.P670L	Substitution - Missense	Skin
COSM5724968	c.4795C>T	p.P1599S	Substitution - Missense	Skin
COSM5361289	c.2607delT	p.Q871fs*2	Deletion - Frameshift	Large_intestine
COSM4041980	c.484G>T	p.V162L	Substitution - Missense	Stomach
COSM4334453	c.103delA	p.I37fs*21	Deletion - Frameshift	Large_intestine
COSM131514	c.5281G>T	p.E1761*	Substitution - Nonsense	Liver
COSM1628605	c.1095delA	p.R366fs*5	Deletion - Frameshift	Liver
COSM1183570	c.1330G>T	p.D444Y	Substitution - Missense	Liver
COSM1167994	c.2128C>T	p.P710S	Substitution - Missense	Skin
COSM1606134	c.1125delG	p.E376fs*15	Deletion - Frameshift	Liver
COSM3986927	c.5062-1G>A	p.?	Unknown	Skin
COSM4767424	c.1715+1G>A	p.?	Unknown	Biliary_tract
COSM1628607	c.1120+8T>G	p.?	Unknown	Liver
COSM4041993	c.4328G>A	p.S1443N	Substitution - Missense	Stomach
COSM3460985	c.5042C>T	p.S1681F	Substitution - Missense	Skin
COSM939509	c.3913C>T	p.P1305S	Substitution - Missense	Endometrium
COSM4663266	c.666_668delAGA	p.E224delE	Deletion - In frame	Large_intestine
COSM3460969	c.2173C>T	p.Q725*	Substitution - Nonsense	Skin
COSM251411	c.5174C>G	p.S1725*	Substitution - Nonsense	Lung
COSM73728	c.2225C>T	p.S742F	Substitution - Missense	Ovary
COSM1245454	c.1624C>T	p.R542*	Substitution - Nonsense	Large_intestine
COSM3710883	c.723T>C	p.V241V	Substitution - coding silent	Upper_aerodigestive_tract
COSM4419333	c.597C>G	p.I199M	Substitution - Missense	Prostate
COSM4663267	c.1625G>A	p.R542Q	Substitution - Missense	Large_intestine
COSM5375178	c.4562A>G	p.D1521G	Substitution - Missense	Skin
COSM3460961	c.647C>T	p.S216F	Substitution - Missense	Skin
COSM5607876	c.3597delA	p.G1200fs*4	Deletion - Frameshift	Skin
COSM1361683	c.1277C>T	p.T426M	Substitution - Missense	Large_intestine
COSM3704149	c.4888C>T	p.Q1630*	Substitution - Nonsense	Liver
COSM4041991	c.3286C>T	p.Q1096*	Substitution - Nonsense	Stomach
COSM1299385	c.3617C>T	p.T1206M	Substitution - Missense	Stomach
COSM3710884	c.2110C>T	p.Q704*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM2067837	c.2809C>T	p.Q937*	Substitution - Nonsense	Skin
COSM1512174	c.820C>T	p.R274*	Substitution - Nonsense	Skin
COSM3704143	c.266T>G	p.L89*	Substitution - Nonsense	Liver
COSM5348618	c.2719_2720insT	p.S907fs*44	Insertion - Frameshift	Liver
COSM1606148	c.4938C>T	p.P1646P	Substitution - coding silent	Liver
COSM5763715	c.3355C>T	p.Q1119*	Substitution - Nonsense	Large_intestine
COSM1606143	c.4190_4191insGACT	p.L1399fs*13	Insertion - Frameshift	Liver
COSM5348619	c.3546_3547insT	p.A1183fs*58	Insertion - Frameshift	Liver
COSM5809471	c.1121-2A>G	p.?	Unknown	Liver
COSM1245459	c.3370C>T	p.Q1124*	Substitution - Nonsense	Oesophagus
COSM2067824	c.2014C>T	p.Q672*	Substitution - Nonsense	Biliary_tract
COSM1183570	c.1330G>T	p.D444Y	Substitution - Missense	Liver
COSM4884873	c.2488C>T	p.Q830*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM5878501	c.1265T>C	p.L422P	Substitution - Missense	Liver
COSM1167955	c.2680C>T	p.Q894*	Substitution - Nonsense	Skin
COSM4989699	c.2833C>A	p.Q945K	Substitution - Missense	Soft_tissue
COSM278971	c.940C>T	p.R314C	Substitution - Missense	Skin
COSM5935836	c.2954C>T	p.P985L	Substitution - Missense	Skin
COSM1167994	c.2128C>T	p.P710S	Substitution - Missense	Skin
COSM3460963	c.811C>T	p.H271Y	Substitution - Missense	Skin
COSM346353	c.2140G>T	p.V714F	Substitution - Missense	Lung
COSM1606141	c.3817C>T	p.R1273*	Substitution - Nonsense	Liver
COSM1746978	c.1062G>A	p.L354L	Substitution - coding silent	Urinary_tract
COSM4041988	c.1547T>C	p.V516A	Substitution - Missense	Stomach
COSM5739622	c.4084T>C	p.C1362R	Substitution - Missense	Small_intestine
COSM2067831	c.2404T>C	p.F802L	Substitution - Missense	Large_intestine
COSM1628615	c.5269A>G	p.T1757A	Substitution - Missense	Liver
COSM1606130	c.81delC	p.H28fs*30	Deletion - Frameshift	Liver
COSM939496	c.821G>A	p.R274Q	Substitution - Missense	Endometrium
COSM3871642	c.2567C>T	p.T856I	Substitution - Missense	Skin
COSM1167991	c.890C>T	p.S297F	Substitution - Missense	Skin
COSM3376253	c.3095A>G	p.Q1032R	Substitution - Missense	Pancreas
COSM5490622	c.4466C>G	p.S1489*	Substitution - Nonsense	Biliary_tract
COSM1628617	c.5328delA	p.N1778fs*13	Deletion - Frameshift	Large_intestine
COSM131531	c.93-1G>A	p.?	Unknown	Liver
COSM693910	c.1119A>C	p.R373S	Substitution - Missense	Lung
COSM5814687	c.783A>T	p.S261S	Substitution - coding silent	Liver
COSM1645192	c.2543_2544insT	p.A849fs*102	Insertion - Frameshift	Liver
COSM1606137	c.2542_2543insT	p.A849fs*102	Insertion - Frameshift	Liver

> Text Mining based Variations

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PMID	Variation	Cancer	Evidence
27270314	mutation	Gastric Adenocarcinoma	Five genes (TP53, BAI1, THSD1, ARID2, and KIAA2022) verified in our study were also mutated at a frequency greater than 5%in the COSMIC database
27175599	mutation	Gastric Adenoma	All MSS gastric adenomas also harbored ARID2 truncating mutations, often as multiple, region-specific ones indicative of convergent evolution
27050151	mutation	Oral Cavity Squamous Cell Carcinoma	Notably, we identified mutations (MLL4, USP9X, ARID2) in cell lines derived from betel quid users that may be associated with this specific risk factor
26998897	mutation	Duodenal Adenocarcinoma	The authors identified recurrent mutations in tumor protein p53 (TP53), KRAS, catenin (cadherin-associated protein) β-1 (CTNNB1), AT-rich interactive domain 2 (ARID2), adenomatous polyposis coli (APC), erb-b2 receptor tyrosine kinase 2 (ERBB2), ARID1A, cadherin-related family member 1 (CDHR1), NRAS, Bcl-2-related ovarian killer (BOK), radial spoke head 14 homolog (chlamydomonas) (RTDR1), cell division cycle 27 (CDC27), catalytic subunit of phosphoinositide-3-kinase (PIK3CA), and SMAD family member 4 (SMAD4)
26920370	mutation	Malignant Ovarian Neoplasm	Other recurrently mutated genes included ETS1, MLH1, PRKDC (3/10 each), and AMER1, ARID2, BCL11A, CREBBP, ERBB2, EXT1, FANCD2, MSH6, NF1, NOTCH1, NUMA1, PDE4DIP, PPP2R1A, RNF213, and SYNE1 (2/10 each).
26284269	mutation	Hepatocellular Carcinoma	ARID2 (ARID2), CTNNB1 (β catenin), tumor protein 53 (p53), and PIK3CA (p110α) mutations are implicated in hepatocellular carcinoma (HCC); and previous work has contributed to thorough molecular characterization of these events; Furthermore, we found that loss of ARID2 protein expression may be associated with recurrence, although further studies must be done to validate these findings in a larger population
26099527	mutation	Hepatocellular Carcinoma	TP53 and CTNNB1 are the next most prevalent mutations, affecting 25%-30% of HCC patients, that, in addition to low-frequency mutated genes (eg, AXIN1, ARID2, ARID1A, TSC1/TSC2, RPS6KA3, KEAP1, MLL2), help define some of the core deregulated pathways in HCC
25790038	mutation	Papillary Renal Cell Carcinoma	We identify BAP1, SETD2, ARID2 and Nrf2 pathway genes (KEAP1, NHE2L2 and CUL3) as probable drivers, together with at least eight other possible drivers; However, only ~10% of tumours harbour detectable pathogenic changes in any one driver gene, and where present, the mutations are often predicted to be present within cancer sub-clones
25393105	mutation	Melanoma	Extension studies using tumors from another 96 patients discovered a large number of truncation mutations in tumor suppressors (TP53 and RB1), protein phosphatases (e.g., PTEN, PTPRB, PTPRD, and PTPRT), as well as chromatin remodeling genes (e.g., ASXL3, MLL2, and ARID2)
25159915	mutation	Hepatocellular Carcinoma	Lower frequency mutations have been reported in ARID1A, ARID2 and JAK1
24379610	mutation	Hepatocellular Carcinoma	High-throughput short-read sequencing of exomes and whole cancer genomes in multiple human hepatocellular carcinoma (HCC) cohorts confirmed previously identified frequently mutated somatic genes, such as TP53, CTNNB1 and AXIN1, and identified several novel genes with moderate mutation frequencies, including ARID1A, ARID2, MLL, MLL2, MLL3, MLL4, IRF2, ATM, CDKN2A, FGF19, PIK3CA, RPS6KA3, JAK1, KEAP1, NFE2L2, C16orf62, LEPR, RAC2, and IL6ST
24292195	mutation	Gingivo-buccal Oral Squamous Cell Carcinoma	Exome sequencing (n=50) and recurrence testing (n=60) reveals that some significantly and frequently altered genes are specific to OSCC-GB (USP9X, MLL4, ARID2, UNC13C and TRPM3), while some others are shared with HNSCC (for example, TP53, FAT1, CASP8, HRAS and NOTCH1).
23103869	mutation	Pancreatic Carcinoma	We define 16 significantly mutated genes, reaffirming known mutations (KRAS, TP53, CDKN2A, SMAD4, MLL3, TGFBR2, ARID1A and SF3B1), and uncover novel mutated genes including additional genes involved in chromatin modification (EPC1 and ARID2), DNA damage repair (ATM) and other mechanisms (ZIM2, MAP2K4, NALCN, SLC16A4 and MAGEA6).
23047306	mutation (loss of function)	Non-Small Cell Lung Carcinoma	Recurrent inactivating mutations of ARID2 in non-small cell lung carcinoma.
22817889	mutation	Melanoma	Analysis of large-scale melanoma exome data by this approach discovered six novel melanoma genes (PPP6C, RAC1, SNX31, TACC1, STK19, and ARID2), three of which-RAC1, PPP6C, and STK19-harbored recurrent and potentially targetable mutations
22095441	mutation (loss of function)	Hepatocellular Carcinoma	Our recent work described novel inactivating mutations of ARID2 (AT-rich interactive domain 2) in four major subtypes of HCC through exomic sequencing of ten HCV-associated HCCs and subsequent evaluation of the tumors from additional affected individuals
21822264	mutation (loss of function)	Hepatocellular Carcinoma	Notably, 18.2% of individuals with HCV-associated HCC in the United States and Europe harbored ARID2 inactivation mutations, suggesting that ARID2 is a tumor suppressor gene that is relatively commonly mutated in this tumor subtype.
22634756	mutation	Hepatocellular Carcinoma	Multiple chromatin regulators, including ARID1A, ARID1B, ARID2, MLL and MLL3, were mutated in 50% of the tumors
24382590	mutation (loss of function)	Colorectal Carcinoma	Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A in microsatellite unstable colorectal cancer
24916674	mutation	Malignant Mesothelioma	Direct sequencing showed that homozygous mutations in SMARCA4, PBRM1 and ARID2 were somatic
25370573	mutation	Lung Carcinoma	Specifically, the mutant-typing of 6 BAF genes, SMARCA4, ARID2, ARID1B, BCL11A, BCL11B and BRD9 was associated with more overall mutations in the lung carcinoma samples
25636086	mutation	Liver Cancer Displaying Biliary Phenotype	The subsequent validation study on 68 LCBs identified recurrent mutations in TERT promoter, chromatin regulators (BAP1, PBRM1 and ARID2), a synapse organization gene (PCLO), IDH genes and KRAS
26221190	mutation	Melanoma	Of the 40 most commonly mutated genes, 12 (30.0%) encoded epigenetic regulators, including genes encoding enzymes involved in histone modification (MECOM, MLL2, SETD2), chromatin remodeling (ARID1B, ARID2), and DNA methylation and demethylation (TET2, IDH1)
26812616	mutation	Esophageal Squamous Cell Carcinoma	Deep sequencing of components of the SWI/SNF complex using a bench-top next generation sequencer revealed that eight of 92 ESCCs (8.7%) had 11 somatic mutations of 7 genes, ARID1A, ARID2, ATRX, PBRM1, SMARCA4, SMARCAL1, and SMARCC1.
28648284	mutation	Intrahepatic Cholangiocarcinoma; Hepatocellular Carcinoma	While ICC and HCC share recurrently mutated genes, including TP53, ARID1A, and ARID2, mitotic checkpoint anomalies distinguish the C1 subtype with key drivers PLK1 and ECT2, whereas the C2 subtype is linked to obesity, Tcell infiltration, and bile acid metabolism.
28529542	mutation	Hepatocellular Carcinoma	Nucleotide changes in coding regions (i.e. TP53, CTNNB1, ARID1A and ARID2) as well as in non-coding regions (i.e. TERT promoter) are considered cancer drivers for HCC development with variable frequencies in different geographic regions depending on the etiology and environmental factors.
28210865	mutation	Melanoma	Apart from mutated BRAF, NRAS, and KIT, a series of new recurrently mutated candidate genes with impact on signaling pathways have been identified such as NF1, PTEN, IDH1, RAC1, ARID2, and TP53.
28179590	mutation	Colon Adenoma	We identified MTOR, ACVR1B, GNAQ, ATM, CNOT1, EP300, ARID2, RET and MAP2K4 mutations for the first time in colon adenomas.
27834349	mutation	Atypical Verruciform Lesion	Eight (73%) and six (55%) of eleven atypical verruciform lesions contained mutations in PIK3CA and ARID2, respectively.

Summary
Symbol	ARID2
Name	AT-rich interaction domain 2
Aliases	KIAA1557; DKFZp686G052; FLJ30619; BAF200; ARID domain-containing protein 2; BRG1-associated factor 200; zinc ......
Location	12q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

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Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant
Q68CP9	4	S	Phosphoserine	-	No	None detected
Q68CP9	631	S	Phosphoserine	-	No	None detected
Q68CP9	635	S	Phosphoserine	-	No	None detected
Q68CP9	653	T	Phosphothreonine	-	No	None detected
Q68CP9	689	S	Phosphoserine	-	No	None detected
Q68CP9	692	T	Phosphothreonine	-	No	None detected
Q68CP9	1300	S	Phosphoserine	-	No	None detected
Q68CP9	1391	S	Phosphoserine	-	No	None detected
Q68CP9	1496	S	Phosphoserine	-	Yes	p.S1496F (cancer: SKCM)

Summary
Symbol	ARID2
Name	AT-rich interaction domain 2
Aliases	KIAA1557; DKFZp686G052; FLJ30619; BAF200; ARID domain-containing protein 2; BRG1-associated factor 200; zinc ......
Location	12q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

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Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	4.966	4.933	-0.056	0.768	NS
BRCA	Breast invasive carcinoma	112	1100	5.607	5.758	0.159	0.0209	NS
CESC	Cervical and endocervical cancers	3	306	4.746	5.15	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	4.935	4.834	-0.107	0.198	NS
ESCA	Esophageal carcinoma	11	185	6.072	5.885	-0.172	0.412	NS
GBM	Glioblastoma multiforme	5	166	4.174	4.8	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	4.947	4.937	-0.027	0.814	NS
KIRC	Kidney renal clear cell carcinoma	72	534	5.411	5.338	-0.048	0.36	NS
KIRP	Kidney renal papillary cell carcinoma	32	291	5.083	4.952	-0.117	0.26	NS
LAML	Acute Myeloid Leukemia	0	173	NA	7.25	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	5.11	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	3.317	3.502	0.178	0.0439	NS
LUAD	Lung adenocarcinoma	59	517	5.006	4.88	-0.066	0.416	NS
LUSC	Lung squamous cell carcinoma	51	501	4.893	5.273	0.358	1.69e-06	NS
OV	Ovarian serous cystadenocarcinoma	0	307	NA	5.666	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	5.022	4.889	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	4.216	4.777	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	5.382	5.167	-0.153	0.0397	NS
READ	Rectum adenocarcinoma	10	167	4.887	4.739	-0.139	0.503	NS
SARC	Sarcoma	2	263	4.367	4.61	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	4.76	4.819	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	5.48	5.828	0.236	0.021	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	5.33	NA	NA	NA
THCA	Thyroid carcinoma	59	509	5.298	5.1	-0.128	0.0173	NS
THYM	Thymoma	2	120	6.026	5.538	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	5.126	5.17	0.065	0.523	NS

> Cancer Cell Line Encyclopedia (CCLE)

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Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	9.1
Autonomic ganglia	CHP212	9
Autonomic ganglia	IMR32	10.1
Autonomic ganglia	KELLY	9.5
Autonomic ganglia	KPNRTBM1	9.6
Autonomic ganglia	KPNSI9S	8.3
Autonomic ganglia	KPNYN	9.8
Autonomic ganglia	MHHNB11	8.6
Autonomic ganglia	NB1	8.9
Autonomic ganglia	NH6	9.7
Autonomic ganglia	SHSY5Y	9.3
Autonomic ganglia	SIMA	9.2
Autonomic ganglia	SKNAS	8.4
Autonomic ganglia	SKNBE2	9.8
Autonomic ganglia	SKNDZ	10.1
Autonomic ganglia	SKNFI	10
Autonomic ganglia	SKNSH	9
Biliary tract	HUCCT1	7.8
Biliary tract	HUH28	7.4
Biliary tract	SNU1079	8.7
Biliary tract	SNU1196	8.1
Biliary tract	SNU245	8.3
Biliary tract	SNU308	4.8
Biliary tract	SNU478	8.4
Bone	143B	8.1
Bone	A673	9.3
Bone	CADOES1	8.3
Bone	CAL78	7.8
Bone	G292CLONEA141B1	8.3
Bone	HOS	8.9
Bone	HS706T	8
Bone	HS737T	7.6
Bone	HS819T	7.6
Bone	HS821T	7.4
Bone	HS822T	7.7
Bone	HS863T	7.3
Bone	HS870T	7.5
Bone	HS888T	7.6
Bone	MG63	8.2
Bone	MHHES1	9.8
Bone	OUMS27	8.1
Bone	RDES	9.4
Bone	SJSA1	7.8
Bone	SKES1	9.7
Bone	SKNMC	9.5
Bone	SW1353	8.1
Bone	T173	7.8
Bone	TC71	9.7
Bone	U2OS	8.3
Breast	AU565	8.9
Breast	BT20	8
Breast	BT474	9.1
Breast	BT483	9.2
Breast	BT549	8.2
Breast	CAL120	7.9
Breast	CAL148	8.5
Breast	CAL51	9.4
Breast	CAL851	7.2
Breast	CAMA1	9.5
Breast	DU4475	9
Breast	EFM192A	8.8
Breast	EFM19	9.1
Breast	EVSAT	8.8
Breast	HCC1143	8.4
Breast	HCC1187	7.6
Breast	HCC1395	7.7
Breast	HCC1419	8.6
Breast	HCC1428	8.3
Breast	HCC1500	8.7
Breast	HCC1569	7.9
Breast	HCC1599	7.7
Breast	HCC1806	7.7
Breast	HCC1937	7.9
Breast	HCC1954	8.1
Breast	HCC202	8.7
Breast	HCC2157	8
Breast	HCC2218	8.9
Breast	HCC38	7.9
Breast	HCC70	7.7
Breast	HDQP1	7.9
Breast	HMC18	8.9
Breast	HS274T	7.3
Breast	HS281T	7.1
Breast	HS343T	7.5
Breast	HS578T	7.5
Breast	HS606T	7.6
Breast	HS739T	8
Breast	HS742T	7.4
Breast	JIMT1	7.6
Breast	KPL1	8.6
Breast	MCF7	8.8
Breast	MDAMB134VI	9.6
Breast	MDAMB157	8
Breast	MDAMB175VII	8.9
Breast	MDAMB231	7.7
Breast	MDAMB361	8.2
Breast	MDAMB415	9.3
Breast	MDAMB436	7.6
Breast	MDAMB453	8.8
Breast	MDAMB468	7.4
Breast	SKBR3	8.9
Breast	T47D	9.3
Breast	UACC812	8.2
Breast	UACC893	8.2
Breast	YMB1	8.8
Breast	ZR751	8.7
Breast	ZR7530	8.7
Central nervous system	1321N1	8
Central nervous system	42MGBA	7.5
Central nervous system	8MGBA	6.5
Central nervous system	A172	7.9
Central nervous system	AM38	8.4
Central nervous system	BECKER	8.2
Central nervous system	CAS1	7.8
Central nervous system	CCFSTTG1	8.1
Central nervous system	D283MED	9.2
Central nervous system	D341MED	9.3
Central nervous system	DAOY	8.2
Central nervous system	DBTRG05MG	8.1
Central nervous system	DKMG	8.1
Central nervous system	GAMG	8
Central nervous system	GB1	7.2
Central nervous system	GI1	8.1
Central nervous system	GMS10	8.5
Central nervous system	GOS3	8.3
Central nervous system	H4	7.8
Central nervous system	HS683	8
Central nervous system	KALS1	8.2
Central nervous system	KG1C	8.4
Central nervous system	KNS42	8.1
Central nervous system	KNS60	8.1
Central nervous system	KNS81	8.2
Central nervous system	KS1	7.6
Central nervous system	LN18	7.5
Central nervous system	LN229	9.2
Central nervous system	M059K	7.5
Central nervous system	MOGGCCM	7.4
Central nervous system	MOGGUVW	8.3
Central nervous system	NMCG1	7.4
Central nervous system	ONS76	8.3
Central nervous system	SF126	8.1
Central nervous system	SF295	8
Central nervous system	SNB19	7.6
Central nervous system	SNU1105	7.5
Central nervous system	SNU201	7.8
Central nervous system	SNU466	7.8
Central nervous system	SNU489	7.4
Central nervous system	SNU626	8
Central nervous system	SNU738	8.6
Central nervous system	SW1088	7.7
Central nervous system	SW1783	7.8
Central nervous system	T98G	7.8
Central nervous system	TM31	8.6
Central nervous system	U118MG	7.4
Central nervous system	U138MG	7.8
Central nervous system	U251MG	7.6
Central nervous system	U87MG	7.7
Central nervous system	YH13	7.5
Central nervous system	YKG1	8.3
Endometrium	AN3CA	7.7
Endometrium	COLO684	7.9
Endometrium	EFE184	8.3
Endometrium	EN	8.8
Endometrium	ESS1	8.7
Endometrium	HEC108	8.3
Endometrium	HEC151	8.9
Endometrium	HEC1A	8.3
Endometrium	HEC1B	8.9
Endometrium	HEC251	9
Endometrium	HEC265	8.9
Endometrium	HEC50B	8.3
Endometrium	HEC59	8.8
Endometrium	HEC6	8.7
Endometrium	ISHIKAWAHERAKLIO02ER	9.5
Endometrium	JHUEM1	8.7
Endometrium	JHUEM2	9.2
Endometrium	JHUEM3	8.6
Endometrium	KLE	7.9
Endometrium	MFE280	8.9
Endometrium	MFE296	8.6
Endometrium	MFE319	8.7
Endometrium	RL952	9
Endometrium	SNGM	8.4
Endometrium	SNU1077	8
Endometrium	SNU685	7.9
Endometrium	TEN	8.6
Haematopoietic and lymphoid	697	9.6
Haematopoietic and lymphoid	A3KAW	8.6
Haematopoietic and lymphoid	A4FUK	9.7
Haematopoietic and lymphoid	ALLSIL	9.1
Haematopoietic and lymphoid	AML193	9
Haematopoietic and lymphoid	AMO1	9.3
Haematopoietic and lymphoid	BCP1	8.8
Haematopoietic and lymphoid	BDCM	8.4
Haematopoietic and lymphoid	BL41	9.2
Haematopoietic and lymphoid	BL70	9.4
Haematopoietic and lymphoid	BV173	9.2
Haematopoietic and lymphoid	CA46	8.6
Haematopoietic and lymphoid	CI1	8.3
Haematopoietic and lymphoid	CMK115	10
Haematopoietic and lymphoid	CMK86	9.1
Haematopoietic and lymphoid	CMK	9
Haematopoietic and lymphoid	CMLT1	9.5
Haematopoietic and lymphoid	COLO775	8.4
Haematopoietic and lymphoid	DAUDI	8.9
Haematopoietic and lymphoid	DB	8.4
Haematopoietic and lymphoid	DEL	8.3
Haematopoietic and lymphoid	DND41	9.5
Haematopoietic and lymphoid	DOHH2	8.6
Haematopoietic and lymphoid	EB1	7.6
Haematopoietic and lymphoid	EB2	7
Haematopoietic and lymphoid	EHEB	8
Haematopoietic and lymphoid	EJM	7.8
Haematopoietic and lymphoid	EM2	8.4
Haematopoietic and lymphoid	EOL1	8.9
Haematopoietic and lymphoid	F36P	9.1
Haematopoietic and lymphoid	GA10	8.6
Haematopoietic and lymphoid	GDM1	8.6
Haematopoietic and lymphoid	GRANTA519	8.5
Haematopoietic and lymphoid	HDLM2	7.9
Haematopoietic and lymphoid	HDMYZ	8.1
Haematopoietic and lymphoid	HEL9217	9.2
Haematopoietic and lymphoid	HEL	9.1
Haematopoietic and lymphoid	HH	7.4
Haematopoietic and lymphoid	HL60	8.7
Haematopoietic and lymphoid	HPBALL	9.3
Haematopoietic and lymphoid	HS604T	7.8
Haematopoietic and lymphoid	HS611T	8.3
Haematopoietic and lymphoid	HS616T	7.8
Haematopoietic and lymphoid	HS751T	7.2
Haematopoietic and lymphoid	HT	8.6
Haematopoietic and lymphoid	HTK	7.8
Haematopoietic and lymphoid	HUNS1	8.5
Haematopoietic and lymphoid	HUT102	8.3
Haematopoietic and lymphoid	HUT78	9.2
Haematopoietic and lymphoid	JEKO1	8.6
Haematopoietic and lymphoid	JK1	9.4
Haematopoietic and lymphoid	JM1	10.4
Haematopoietic and lymphoid	JURKAT	9.7
Haematopoietic and lymphoid	JURLMK1	9
Haematopoietic and lymphoid	JVM2	8.1
Haematopoietic and lymphoid	JVM3	8.7
Haematopoietic and lymphoid	K562	8.1
Haematopoietic and lymphoid	KARPAS299	8.6
Haematopoietic and lymphoid	KARPAS422	8.2
Haematopoietic and lymphoid	KARPAS620	9.9
Haematopoietic and lymphoid	KASUMI1	9.6
Haematopoietic and lymphoid	KASUMI2	9
Haematopoietic and lymphoid	KASUMI6	8.6
Haematopoietic and lymphoid	KCL22	8.9
Haematopoietic and lymphoid	KE37	9.4
Haematopoietic and lymphoid	KE97	9.1
Haematopoietic and lymphoid	KG1	8.9
Haematopoietic and lymphoid	KHM1B	9.3
Haematopoietic and lymphoid	KIJK	8.2
Haematopoietic and lymphoid	KMH2	9.2
Haematopoietic and lymphoid	KMM1	9.6
Haematopoietic and lymphoid	KMS11	9.9
Haematopoietic and lymphoid	KMS12BM	9.4
Haematopoietic and lymphoid	KMS18	8.9
Haematopoietic and lymphoid	KMS20	8.5
Haematopoietic and lymphoid	KMS21BM	9.2
Haematopoietic and lymphoid	KMS26	9.1
Haematopoietic and lymphoid	KMS27	8.5
Haematopoietic and lymphoid	KMS28BM	8.9
Haematopoietic and lymphoid	KMS34	10.4
Haematopoietic and lymphoid	KO52	9.2
Haematopoietic and lymphoid	KOPN8	7.9
Haematopoietic and lymphoid	KU812	8.5
Haematopoietic and lymphoid	KYO1	8
Haematopoietic and lymphoid	L1236	8
Haematopoietic and lymphoid	L363	9
Haematopoietic and lymphoid	L428	8.1
Haematopoietic and lymphoid	L540	8.7
Haematopoietic and lymphoid	LAMA84	9.2
Haematopoietic and lymphoid	LOUCY	9.5
Haematopoietic and lymphoid	LP1	9.2
Haematopoietic and lymphoid	M07E	9.3
Haematopoietic and lymphoid	MC116	8.9
Haematopoietic and lymphoid	ME1	8.1
Haematopoietic and lymphoid	MEC1	7.9
Haematopoietic and lymphoid	MEC2	8.3
Haematopoietic and lymphoid	MEG01	8.7
Haematopoietic and lymphoid	MHHCALL2	9.1
Haematopoietic and lymphoid	MHHCALL3	9.2
Haematopoietic and lymphoid	MHHCALL4	9.4
Haematopoietic and lymphoid	MINO	8.6
Haematopoietic and lymphoid	MJ	8
Haematopoietic and lymphoid	MM1S	9.8
Haematopoietic and lymphoid	MOLM13	9.2
Haematopoietic and lymphoid	MOLM16	9.1
Haematopoietic and lymphoid	MOLM6	8.4
Haematopoietic and lymphoid	MOLP2	7.8
Haematopoietic and lymphoid	MOLP8	9.2
Haematopoietic and lymphoid	MOLT13	9.8
Haematopoietic and lymphoid	MOLT16	9.1
Haematopoietic and lymphoid	MOLT4	9.2
Haematopoietic and lymphoid	MONOMAC1	9.1
Haematopoietic and lymphoid	MONOMAC6	9.2
Haematopoietic and lymphoid	MOTN1	7.3
Haematopoietic and lymphoid	MUTZ5	9
Haematopoietic and lymphoid	MV411	9.2
Haematopoietic and lymphoid	NALM19	9.5
Haematopoietic and lymphoid	NALM1	9.1
Haematopoietic and lymphoid	NALM6	8.8
Haematopoietic and lymphoid	NAMALWA	8.9
Haematopoietic and lymphoid	NB4	9.2
Haematopoietic and lymphoid	NCIH929	9.1
Haematopoietic and lymphoid	NCO2	8.9
Haematopoietic and lymphoid	NOMO1	9.1
Haematopoietic and lymphoid	NUDHL1	9.7
Haematopoietic and lymphoid	NUDUL1	9
Haematopoietic and lymphoid	OCIAML2	9.2
Haematopoietic and lymphoid	OCIAML3	8.8
Haematopoietic and lymphoid	OCIAML5	8.8
Haematopoietic and lymphoid	OCILY10	8.9
Haematopoietic and lymphoid	OCILY19	8.9
Haematopoietic and lymphoid	OCILY3	8.8
Haematopoietic and lymphoid	OCIM1	8.9
Haematopoietic and lymphoid	OPM2	9.9
Haematopoietic and lymphoid	P12ICHIKAWA	9.5
Haematopoietic and lymphoid	P31FUJ	8.3
Haematopoietic and lymphoid	P3HR1	8.8
Haematopoietic and lymphoid	PCM6	8
Haematopoietic and lymphoid	PEER	10.1
Haematopoietic and lymphoid	PF382	9.9
Haematopoietic and lymphoid	PFEIFFER	8.4
Haematopoietic and lymphoid	PL21	9.5
Haematopoietic and lymphoid	RAJI	8.6
Haematopoietic and lymphoid	RCHACV	9.5
Haematopoietic and lymphoid	REC1	8.4
Haematopoietic and lymphoid	REH	9.5
Haematopoietic and lymphoid	RI1	8.8
Haematopoietic and lymphoid	RL	9
Haematopoietic and lymphoid	RPMI8226	9.4
Haematopoietic and lymphoid	RPMI8402	9.4
Haematopoietic and lymphoid	RS411	9
Haematopoietic and lymphoid	SEM	9.8
Haematopoietic and lymphoid	SET2	8.9
Haematopoietic and lymphoid	SIGM5	9.2
Haematopoietic and lymphoid	SKM1	7.9
Haematopoietic and lymphoid	SKMM2	8.7
Haematopoietic and lymphoid	SR786	8.4
Haematopoietic and lymphoid	ST486	9
Haematopoietic and lymphoid	SUDHL10	8
Haematopoietic and lymphoid	SUDHL1	8.3
Haematopoietic and lymphoid	SUDHL4	8.8
Haematopoietic and lymphoid	SUDHL5	8.9
Haematopoietic and lymphoid	SUDHL6	8.6
Haematopoietic and lymphoid	SUDHL8	9.3
Haematopoietic and lymphoid	SUPB15	9.6
Haematopoietic and lymphoid	SUPHD1	8.3
Haematopoietic and lymphoid	SUPM2	8
Haematopoietic and lymphoid	SUPT11	7.9
Haematopoietic and lymphoid	SUPT1	9.4
Haematopoietic and lymphoid	TALL1	9.6
Haematopoietic and lymphoid	TF1	9.9
Haematopoietic and lymphoid	THP1	9.6
Haematopoietic and lymphoid	TO175T	7.9
Haematopoietic and lymphoid	TOLEDO	10
Haematopoietic and lymphoid	U266B1	9.1
Haematopoietic and lymphoid	U937	8.6
Haematopoietic and lymphoid	UT7	9.1
Haematopoietic and lymphoid	WSUDLCL2	8.4
Kidney	769P	8.5
Kidney	786O	7.8
Kidney	A498	8.2
Kidney	A704	9
Kidney	ACHN	8.6
Kidney	BFTC909	8.3
Kidney	CAKI1	8.1
Kidney	CAKI2	8.2
Kidney	CAL54	8.4
Kidney	KMRC1	8.8
Kidney	KMRC20	8.3
Kidney	KMRC2	8.6
Kidney	KMRC3	8.8
Kidney	OSRC2	8.7
Kidney	RCC10RGB	8.7
Kidney	SNU1272	8.1
Kidney	SNU349	8.4
Kidney	TUHR10TKB	8.3
Kidney	TUHR14TKB	8.9
Kidney	TUHR4TKB	9
Kidney	VMRCRCW	8.1
Kidney	VMRCRCZ	8.4
Large intestine	C2BBE1	9
Large intestine	CCK81	8.6
Large intestine	CL11	7.8
Large intestine	CL14	7.9
Large intestine	CL34	8
Large intestine	CL40	8.4
Large intestine	COLO205	8.4
Large intestine	COLO320	9.1
Large intestine	COLO678	8.4
Large intestine	CW2	7.9
Large intestine	DLD1	8
Large intestine	GP2D	8.6
Large intestine	HCC56	8.7
Large intestine	HCT116	8.5
Large intestine	HCT15	8.3
Large intestine	HS675T	7.7
Large intestine	HS698T	7.3
Large intestine	HT115	8.9
Large intestine	HT29	8.2
Large intestine	HT55	8.3
Large intestine	KM12	8.3
Large intestine	LOVO	8.8
Large intestine	LS1034	8.2
Large intestine	LS123	8.4
Large intestine	LS180	8.8
Large intestine	LS411N	8.7
Large intestine	LS513	8.1
Large intestine	MDST8	7.3
Large intestine	NCIH508	8.4
Large intestine	NCIH716	9
Large intestine	NCIH747	8.2
Large intestine	OUMS23	9.2
Large intestine	RCM1	8.3
Large intestine	RKO	8.6
Large intestine	SKCO1	8.7
Large intestine	SNU1040	7.6
Large intestine	SNU1197	7.3
Large intestine	SNU175	9.1
Large intestine	SNU283	8.5
Large intestine	SNU407	8.2
Large intestine	SNU503	8.7
Large intestine	SNU61	8.3
Large intestine	SNU81	8.3
Large intestine	SNUC1	8.4
Large intestine	SNUC2A	9.2
Large intestine	SNUC4	8.4
Large intestine	SNUC5	8.9
Large intestine	SW1116	8.4
Large intestine	SW1417	8.3
Large intestine	SW1463	8.6
Large intestine	SW403	8.5
Large intestine	SW480	8.3
Large intestine	SW48	8.9
Large intestine	SW620	9
Large intestine	SW837	7.7
Large intestine	SW948	8.8
Large intestine	T84	8.2
Liver	ALEXANDERCELLS	8.4
Liver	C3A	8.6
Liver	HEP3B217	8.2
Liver	HEPG2	8.2
Liver	HLE	8.5
Liver	HLF	8.4
Liver	HUH1	8
Liver	HUH6	9.2
Liver	HUH7	8.9
Liver	JHH1	8.9
Liver	JHH2	7.6
Liver	JHH4	8.3
Liver	JHH5	8.5
Liver	JHH6	8.3
Liver	JHH7	9.1
Liver	LI7	8.9
Liver	PLCPRF5	8.6
Liver	SKHEP1	8.7
Liver	SNU182	7.7
Liver	SNU387	8.2
Liver	SNU398	9.1
Liver	SNU423	7.9
Liver	SNU449	8.1
Liver	SNU475	8.1
Liver	SNU761	8.7
Liver	SNU878	7.4
Liver	SNU886	7.9
Lung	A549	8.7
Lung	ABC1	9.3
Lung	BEN	8
Lung	CAL12T	7.9
Lung	CALU1	7.4
Lung	CALU3	7.2
Lung	CALU6	8.7
Lung	CHAGOK1	10.4
Lung	COLO668	8.6
Lung	COLO699	9.2
Lung	CORL105	7
Lung	CORL23	7.6
Lung	CORL24	9.2
Lung	CORL279	8.6
Lung	CORL311	9.4
Lung	CORL47	8.4
Lung	CORL51	9.1
Lung	CORL88	8.9
Lung	CORL95	8.8
Lung	CPCN	9.1
Lung	DMS114	9.6
Lung	DMS153	8.5
Lung	DMS273	7.9
Lung	DMS454	8.6
Lung	DMS53	9.7
Lung	DMS79	8.9
Lung	DV90	8.6
Lung	EBC1	7.9
Lung	EPLC272H	7.6
Lung	HARA	8.6
Lung	HCC1171	7.6
Lung	HCC1195	7
Lung	HCC15	8.3
Lung	HCC2279	7
Lung	HCC2935	7.9
Lung	HCC33	8.9
Lung	HCC366	8.1
Lung	HCC4006	7.5
Lung	HCC44	7.6
Lung	HCC78	7.9
Lung	HCC827	7.6
Lung	HCC95	7.9
Lung	HLC1	9.1
Lung	HLFA	7.2
Lung	HS229T	7.7
Lung	HS618T	7.4
Lung	IALM	8.1
Lung	KNS62	7.8
Lung	LC1F	8.1
Lung	LC1SQSF	8.1
Lung	LCLC103H	8.1
Lung	LCLC97TM1	8.7
Lung	LK2	10.6
Lung	LOUNH91	7.6
Lung	LU65	8.2
Lung	LU99	8.5
Lung	LUDLU1	8.2
Lung	LXF289	8
Lung	MORCPR	9
Lung	NCIH1048	9.6
Lung	NCIH1092	10
Lung	NCIH1105	9.4
Lung	NCIH1155	9.1
Lung	NCIH1184	9.4
Lung	NCIH1299	9.1
Lung	NCIH1339	8.4
Lung	NCIH1341	8.8
Lung	NCIH1355	9.1
Lung	NCIH1373	8.3
Lung	NCIH1385	8.7
Lung	NCIH1395	8.4
Lung	NCIH1435	8.3
Lung	NCIH1436	9.2
Lung	NCIH1437	8.7
Lung	NCIH146	9.1
Lung	NCIH1563	7.7
Lung	NCIH1568	9.1
Lung	NCIH1573	9.4
Lung	NCIH1581	9.3
Lung	NCIH1618	9.3
Lung	NCIH1623	9.8
Lung	NCIH1648	7.9
Lung	NCIH1650	7.3
Lung	NCIH1651	8.8
Lung	NCIH1666	8.5
Lung	NCIH1693	8.7
Lung	NCIH1694	9
Lung	NCIH1703	8.6
Lung	NCIH1734	9
Lung	NCIH1755	8.4
Lung	NCIH1781	5.4
Lung	NCIH1792	7.3
Lung	NCIH1793	7.9
Lung	NCIH1836	9.5
Lung	NCIH1838	6.4
Lung	NCIH1869	7.7
Lung	NCIH1876	9.5
Lung	NCIH1915	7.8
Lung	NCIH1930	11.2
Lung	NCIH1944	8.6
Lung	NCIH1963	9.5
Lung	NCIH196	8
Lung	NCIH1975	7.2
Lung	NCIH2009	8
Lung	NCIH2023	8.5
Lung	NCIH2029	9
Lung	NCIH2030	8.6
Lung	NCIH2066	8.7
Lung	NCIH2081	9.3
Lung	NCIH2085	8.5
Lung	NCIH2087	7.7
Lung	NCIH209	8.8
Lung	NCIH2106	6.9
Lung	NCIH2110	8.1
Lung	NCIH211	8.6
Lung	NCIH2122	7.9
Lung	NCIH2126	9.1
Lung	NCIH2141	8.7
Lung	NCIH2170	8
Lung	NCIH2171	9
Lung	NCIH2172	8.3
Lung	NCIH2196	9
Lung	NCIH2227	8.5
Lung	NCIH2228	7.4
Lung	NCIH226	8.8
Lung	NCIH2286	8.9
Lung	NCIH2291	7.6
Lung	NCIH2342	6.3
Lung	NCIH2347	8
Lung	NCIH23	9.1
Lung	NCIH2405	8.3
Lung	NCIH2444	7.9
Lung	NCIH292	7.7
Lung	NCIH322	8.2
Lung	NCIH3255	7.6
Lung	NCIH358	7.9
Lung	NCIH441	4.1
Lung	NCIH446	8.6
Lung	NCIH460	8.2
Lung	NCIH510	8
Lung	NCIH520	8.8
Lung	NCIH522	8.7
Lung	NCIH524	8.4
Lung	NCIH526	8.4
Lung	NCIH596	7.1
Lung	NCIH647	8
Lung	NCIH650	8.6
Lung	NCIH661	8.9
Lung	NCIH69	9.6
Lung	NCIH727	7.8
Lung	NCIH810	8.8
Lung	NCIH82	9.4
Lung	NCIH838	8.2
Lung	NCIH841	8.5
Lung	NCIH854	8
Lung	NCIH889	8.6
Lung	PC14	8
Lung	RERFLCAD1	8.3
Lung	RERFLCAD2	7.9
Lung	RERFLCAI	8.4
Lung	RERFLCKJ	8.5
Lung	RERFLCMS	8.7
Lung	RERFLCSQ1	7.8
Lung	SBC5	9.1
Lung	SCLC21H	8.7
Lung	SHP77	8.4
Lung	SKLU1	8.2
Lung	SKMES1	7.3
Lung	SQ1	6.7
Lung	SW1271	8.6
Lung	SW1573	9.2
Lung	SW900	8.1
Lung	VMRCLCD	8.2
Lung	VMRCLCP	8.3
Oesophagus	COLO680N	8.2
Oesophagus	ECGI10	9.2
Oesophagus	KYSE140	9
Oesophagus	KYSE150	7.2
Oesophagus	KYSE180	8.5
Oesophagus	KYSE270	7.9
Oesophagus	KYSE30	8.2
Oesophagus	KYSE410	9
Oesophagus	KYSE450	8.6
Oesophagus	KYSE510	8.1
Oesophagus	KYSE520	8.7
Oesophagus	KYSE70	8.9
Oesophagus	OE19	4.4
Oesophagus	OE33	8.7
Oesophagus	TE10	8.7
Oesophagus	TE11	8.5
Oesophagus	TE14	9.2
Oesophagus	TE15	9.2
Oesophagus	TE1	8.3
Oesophagus	TE4	8.6
Oesophagus	TE5	8.6
Oesophagus	TE6	8.4
Oesophagus	TE8	8.7
Oesophagus	TE9	8.5
Oesophagus	TT	8.8
Ovary	59M	7.4
Ovary	A2780	9.3
Ovary	CAOV3	8
Ovary	CAOV4	9.1
Ovary	COLO704	8.8
Ovary	COV318	7.7
Ovary	COV362	7.9
Ovary	COV434	9.2
Ovary	COV504	7.9
Ovary	COV644	8.7
Ovary	EFO21	8.6
Ovary	EFO27	8.6
Ovary	ES2	8.1
Ovary	FUOV1	8.2
Ovary	HEYA8	7.7
Ovary	HS571T	7.3
Ovary	IGROV1	8.7
Ovary	JHOC5	8.7
Ovary	JHOM1	8.3
Ovary	JHOM2B	8.2
Ovary	JHOS2	7.2
Ovary	JHOS4	8.5
Ovary	KURAMOCHI	8
Ovary	MCAS	8
Ovary	NIHOVCAR3	8.7
Ovary	OAW28	8.6
Ovary	OAW42	8.7
Ovary	OC314	8.8
Ovary	OC316	8.8
Ovary	ONCODG1	8.4
Ovary	OV56	7.8
Ovary	OV7	8
Ovary	OV90	8.5
Ovary	OVCAR4	9.2
Ovary	OVCAR8	7.7
Ovary	OVISE	8.2
Ovary	OVK18	8.5
Ovary	OVKATE	8.3
Ovary	OVMANA	9.1
Ovary	OVSAHO	9
Ovary	OVTOKO	8.4
Ovary	RMGI	7.4
Ovary	RMUGS	7.7
Ovary	SKOV3	8.4
Ovary	SNU119	8.4
Ovary	SNU840	8.3
Ovary	SNU8	8.3
Ovary	TOV112D	9.5
Ovary	TOV21G	8.6
Ovary	TYKNU	8.1
Pancreas	ASPC1	8.1
Pancreas	BXPC3	8
Pancreas	CAPAN1	7.9
Pancreas	CAPAN2	8.4
Pancreas	CFPAC1	7.8
Pancreas	DANG	7.1
Pancreas	HPAC	8.8
Pancreas	HPAFII	8.2
Pancreas	HS766T	7.3
Pancreas	HUPT3	7.4
Pancreas	HUPT4	7.5
Pancreas	KCIMOH1	8.6
Pancreas	KLM1	7.6
Pancreas	KP2	8.2
Pancreas	KP3	8.6
Pancreas	KP4	9.4
Pancreas	L33	7.8
Pancreas	MIAPACA2	7.8
Pancreas	PANC0203	8.2
Pancreas	PANC0213	7.7
Pancreas	PANC0327	8.4
Pancreas	PANC0403	8.1
Pancreas	PANC0504	8.5
Pancreas	PANC0813	8
Pancreas	PANC1005	8.3
Pancreas	PANC1	8.5
Pancreas	PATU8902	8.7
Pancreas	PATU8988S	9
Pancreas	PATU8988T	8.7
Pancreas	PK1	8.5
Pancreas	PK45H	7.6
Pancreas	PK59	8.9
Pancreas	PL45	8.6
Pancreas	PSN1	8.1
Pancreas	QGP1	9.8
Pancreas	SNU213	7.5
Pancreas	SNU324	8.6
Pancreas	SNU410	7.9
Pancreas	SU8686	7.8
Pancreas	SUIT2	8.4
Pancreas	SW1990	8.6
Pancreas	T3M4	7.4
Pancreas	TCCPAN2	7.9
Pancreas	YAPC	8.3
Pleura	ACCMESO1	7.8
Pleura	DM3	6.7
Pleura	ISTMES1	7.9
Pleura	ISTMES2	8.6
Pleura	JL1	8
Pleura	MPP89	7.6
Pleura	MSTO211H	8.6
Pleura	NCIH2052	7.6
Pleura	NCIH2452	8.4
Pleura	NCIH28	8.9
Prostate	22RV1	10
Prostate	DU145	8.4
Prostate	LNCAPCLONEFGC	8.5
Prostate	MDAPCA2B	8.4
Prostate	NCIH660	8.3
Prostate	PC3	7.2
Prostate	VCAP	9.2
Salivary gland	A253	8.4
Salivary gland	YD15	7.6
Skin	A101D	8.2
Skin	A2058	8
Skin	A375	8.1
Skin	C32	8.4
Skin	CHL1	8.4
Skin	CJM	9
Skin	COLO679	8
Skin	COLO741	8.5
Skin	COLO783	8
Skin	COLO792	6.8
Skin	COLO800	8
Skin	COLO818	8.2
Skin	COLO829	7.8
Skin	COLO849	7.3
Skin	G361	8.1
Skin	GRM	7.8
Skin	HMCB	8.5
Skin	HS294T	7.6
Skin	HS600T	7.4
Skin	HS688AT	7.6
Skin	HS695T	7.6
Skin	HS839T	7.4
Skin	HS852T	7.5
Skin	HS895T	7.1
Skin	HS934T	7.2
Skin	HS936T	8.1
Skin	HS939T	8.2
Skin	HS940T	7.7
Skin	HS944T	7.3
Skin	HT144	8.4
Skin	IGR1	8.8
Skin	IGR37	6.9
Skin	IGR39	7.4
Skin	IPC298	7.7
Skin	K029AX	7.7
Skin	LOXIMVI	7.8
Skin	MALME3M	8.1
Skin	MDAMB435S	7.4
Skin	MELHO	8.4
Skin	MELJUSO	7.1
Skin	MEWO	8.5
Skin	RPMI7951	7.7
Skin	RVH421	8.6
Skin	SH4	7.9
Skin	SKMEL1	8.4
Skin	SKMEL24	7.7
Skin	SKMEL28	7.5
Skin	SKMEL2	7.8
Skin	SKMEL30	8.1
Skin	SKMEL31	7.8
Skin	SKMEL3	7.7
Skin	SKMEL5	8
Skin	UACC257	7.3
Skin	UACC62	8.4
Skin	WM115	7.6
Skin	WM1799	8
Skin	WM2664	7.8
Skin	WM793	7.1
Skin	WM88	8.4
Skin	WM983B	8
Small intestine	HUTU80	10.1
Soft tissue	A204	8.5
Soft tissue	G401	8.7
Soft tissue	G402	8.7
Soft tissue	GCT	7.8
Soft tissue	HS729	8.1
Soft tissue	HT1080	8.3
Soft tissue	KYM1	8.5
Soft tissue	MESSA	8.9
Soft tissue	RD	8.2
Soft tissue	RH30	7.8
Soft tissue	RH41	8.7
Soft tissue	RKN	7.9
Soft tissue	S117	8.3
Soft tissue	SJRH30	9.4
Soft tissue	SKLMS1	8.1
Soft tissue	SKUT1	9
Soft tissue	TE125T	7.5
Soft tissue	TE159T	8
Soft tissue	TE441T	8.1
Soft tissue	TE617T	9.4
Stomach	2313287	8.5
Stomach	AGS	9
Stomach	AZ521	9.4
Stomach	ECC10	9
Stomach	ECC12	8.4
Stomach	FU97	8.9
Stomach	GCIY	8.7
Stomach	GSS	9.3
Stomach	GSU	8.5
Stomach	HGC27	9.2
Stomach	HS746T	8.3
Stomach	HUG1N	7.9
Stomach	IM95	7.8
Stomach	KATOIII	8
Stomach	KE39	8.5
Stomach	LMSU	8.7
Stomach	MKN1	7.9
Stomach	MKN45	7.4
Stomach	MKN74	8.1
Stomach	MKN7	6.3
Stomach	NCCSTCK140	7.9
Stomach	NCIN87	8.8
Stomach	NUGC2	7.9
Stomach	NUGC3	6.5
Stomach	NUGC4	8.8
Stomach	OCUM1	8
Stomach	RERFGC1B	8.9
Stomach	SH10TC	7.8
Stomach	SNU16	8.7
Stomach	SNU1	9.2
Stomach	SNU216	8
Stomach	SNU520	7.5
Stomach	SNU5	7.8
Stomach	SNU601	8.1
Stomach	SNU620	8.2
Stomach	SNU668	7.2
Stomach	SNU719	8.1
Stomach	TGBC11TKB	9.2
Thyroid	8305C	7.4
Thyroid	8505C	7.6
Thyroid	BCPAP	8.2
Thyroid	BHT101	8.1
Thyroid	CAL62	8.5
Thyroid	CGTHW1	7.1
Thyroid	FTC133	7.5
Thyroid	FTC238	8
Thyroid	ML1	8.6
Thyroid	SW579	7.2
Thyroid	TT2609C02	8.3
Thyroid	TT	8.3
Upper aerodigestive tract	BHY	7.7
Upper aerodigestive tract	BICR16	7.5
Upper aerodigestive tract	BICR18	8
Upper aerodigestive tract	BICR22	8.4
Upper aerodigestive tract	BICR31	7.8
Upper aerodigestive tract	BICR56	8.5
Upper aerodigestive tract	BICR6	8.4
Upper aerodigestive tract	CAL27	7.9
Upper aerodigestive tract	CAL33	8.1
Upper aerodigestive tract	DETROIT562	8.1
Upper aerodigestive tract	FADU	8.8
Upper aerodigestive tract	HS840T	7.5
Upper aerodigestive tract	HSC2	8.1
Upper aerodigestive tract	HSC3	8.4
Upper aerodigestive tract	HSC4	8.8
Upper aerodigestive tract	PECAPJ15	8.5
Upper aerodigestive tract	PECAPJ34CLONEC12	8.1
Upper aerodigestive tract	PECAPJ41CLONED2	7.9
Upper aerodigestive tract	PECAPJ49	7.9
Upper aerodigestive tract	SCC15	7.8
Upper aerodigestive tract	SCC25	7.8
Upper aerodigestive tract	SCC4	8.4
Upper aerodigestive tract	SCC9	7.4
Upper aerodigestive tract	SNU1076	7.7
Upper aerodigestive tract	SNU1214	7.8
Upper aerodigestive tract	SNU46	7.6
Upper aerodigestive tract	SNU899	7.8
Upper aerodigestive tract	YD10B	8.2
Upper aerodigestive tract	YD38	8.2
Upper aerodigestive tract	YD8	8.3
Urinary tract	5637	7.7
Urinary tract	639V	9
Urinary tract	647V	8
Urinary tract	BC3C	8.2
Urinary tract	BFTC905	8.5
Urinary tract	CAL29	8.6
Urinary tract	HS172T	6.9
Urinary tract	HT1197	7.9
Urinary tract	HT1376	7.8
Urinary tract	J82	7.8
Urinary tract	JMSU1	8.3
Urinary tract	KMBC2	8.7
Urinary tract	KU1919	8.5
Urinary tract	RT11284	8.5
Urinary tract	RT112	7.9
Urinary tract	RT4	8.5
Urinary tract	SCABER	8.2
Urinary tract	SW1710	8.3
Urinary tract	SW780	8.7
Urinary tract	T24	8
Urinary tract	TCCSUP	7.4
Urinary tract	UMUC1	7.2
Urinary tract	UMUC3	9.8
Urinary tract	VMCUB1	8.4

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	5
Adrenal gland	5.8
Appendix	9.3
Bone marrow	8
Breast	9.3
Cerebral cortex	6.7
Cervix, uterine	10.4
Colon	5.9
Duodenum	5.1
Endometrium	11.5
Epididymis	7.7
Esophagus	7
Fallopian tube	10.4
Gallbladder	8.6
Heart muscle	3.2
Kidney	6.9
Liver	2.6
Lung	8.2
Lymph node	8.8
Ovary	10.3
Pancreas	1.1
Parathyroid gland	21.6
Placenta	10.2
Prostate	11.4
Rectum	6.8
Salivary gland	2.6
Seminal vesicle	8.6
Skeletal muscle	1.3
Skin	10.4
Small intestine	6.2
Smooth muscle	9
Spleen	8.3
Stomach	5.8
Testis	47.3
Thyroid gland	14.6
Tonsil	8.6
Urinary bladder	7.1

> Text Mining based Expression

[ TOP ]

PMID	Expression	Cancer	Evidence
27035278	altered expression	Hepatocellular Carcinoma	Notably, alterations of ARID2 expression abrogated the effects of miR155 on HCC cell proliferation, cell cycle and apoptosis
26169693	underexpression	Hepatocellular Carcinoma	As a result, ARID2 expression in hepatocellular carcinoma (HCC) was decreased
25502816	altered expression	Hepatocellular Carcinoma	Sequencing analysis focused on nine genes typically altered during liver carcinogenesis, i.e. ARID2, AXIN1, BRAF, CTNNB1, NFE2L2, H/K/N-RAS, and TP53
26637902	loss of expression	Gastric Carcinoma	Loss of ARID1B and ARID2 was also related to tumor progression, but their relationship was weaker than that of ARID1A.

Summary
Symbol	ARID2
Name	AT-rich interaction domain 2
Aliases	KIAA1557; DKFZp686G052; FLJ30619; BAF200; ARID domain-containing protein 2; BRG1-associated factor 200; zinc ......
Location	12q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.461	1.19e-22	16.8	61.9	21.3	Neutral
BRCA	Breast invasive carcinoma	1075	0.392	1.02e-40	13.7	66	20.3	Neutral
CESC	Cervical and endocervical cancers	292	0.322	1.89e-08	5.5	76.7	17.8	Neutral
COAD	Colon adenocarcinoma	449	0.38	7.53e-17	9.6	68.8	21.6	Neutral
ESCA	Esophageal carcinoma	183	0.601	2.34e-19	23.5	58.5	18	Neutral
GBM	Glioblastoma multiforme	147	0.44	2.48e-08	11.6	78.2	10.2	Neutral
HNSC	Head and Neck squamous cell carcinoma	514	0.404	1.18e-21	10.1	72.4	17.5	Neutral
KIRC	Kidney renal clear cell carcinoma	525	0.246	1.07e-08	1	76.6	22.5	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	0.315	4.49e-08	0.3	60.8	38.9	Gain
LAML	Acute Myeloid Leukemia	166	0.019	0.808	1.8	98.2	0	Neutral
LGG	Brain Lower Grade Glioma	513	0.344	1.03e-15	13.8	83.4	2.7	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.268	2.21e-07	12.6	74.2	13.2	Neutral
LUAD	Lung adenocarcinoma	512	0.525	1.36e-37	21.3	52	26.8	Neutral
LUSC	Lung squamous cell carcinoma	498	0.498	1.28e-32	11.4	55.4	33.1	Neutral
OV	Ovarian serous cystadenocarcinoma	300	0.762	4.37e-58	16	47	37	Gain
PAAD	Pancreatic adenocarcinoma	177	0.449	3.6e-10	15.3	71.8	13	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	0.334	1.36e-05	1.9	91.4	6.8	Neutral
PRAD	Prostate adenocarcinoma	491	0.208	3.24e-06	6.5	89.8	3.7	Neutral
READ	Rectum adenocarcinoma	164	0.451	1.32e-09	12.2	73.2	14.6	Neutral
SARC	Sarcoma	255	0.271	1.16e-05	26.3	58.4	15.3	Neutral
SKCM	Skin Cutaneous Melanoma	367	0.245	2.09e-06	22.6	64.9	12.5	Neutral
STAD	Stomach adenocarcinoma	413	0.545	2.79e-33	13.6	65.9	20.6	Neutral
TGCT	Testicular Germ Cell Tumors	150	0.499	8.43e-11	0.7	36	63.3	Gain
THCA	Thyroid carcinoma	497	0.179	6.07e-05	0	97.2	2.8	Neutral
THYM	Thymoma	119	0.141	0.127	5.9	90.8	3.4	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.292	5.22e-12	5.4	79.9	14.7	Neutral

Summary
Symbol	ARID2
Name	AT-rich interaction domain 2
Aliases	KIAA1557; DKFZp686G052; FLJ30619; BAF200; ARID domain-containing protein 2; BRG1-associated factor 200; zinc ......
Location	12q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

[ TOP ]

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.245	3.51e-07	17	408	0.001	0.0136	NS/NA
BRCA	Breast invasive carcinoma	-0.239	1.25e-12	83	785	0.001	0.000341	NS/NA
CESC	Cervical and endocervical cancers	-0.121	0.033	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.082	0.146	19	297	0.002	0.0332	NS/NA
ESCA	Esophageal carcinoma	-0.4	1.03e-08	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	0.091	0.471	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.401	0	20	522	0.004	7.22e-10	NS/NA
KIRC	Kidney renal clear cell carcinoma	-0.206	0.00013	24	319	0.052	0.00113	NS/NA
KIRP	Kidney renal papillary cell carcinoma	-0.311	4.97e-08	23	275	0.004	2.31e-10	NS/NA
LAML	Acute Myeloid Leukemia	0.002	0.984	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	-0.239	2.92e-08	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.06	0.225	41	373	0.056	2.29e-05	NS/NA
LUAD	Lung adenocarcinoma	-0.084	0.0677	21	456	0.033	0.173	NS/NA
LUSC	Lung squamous cell carcinoma	-0.188	0.000243	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	-0.883	0.00308	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.338	3.37e-06	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.087	0.239	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.35	9.61e-17	35	498	0.007	7.26e-18	NS/NA
READ	Rectum adenocarcinoma	-0.181	0.0699	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.33	4.98e-08	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.339	5.35e-14	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.168	0.00115	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.076	0.343	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.106	0.0125	50	509	0	0.86	NS/NA
THYM	Thymoma	-0.131	0.149	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.165	0.000374	34	431	-0.001	0.933	NS/NA

Summary
Symbol	ARID2
Name	AT-rich interaction domain 2
Aliases	KIAA1557; DKFZp686G052; FLJ30619; BAF200; ARID domain-containing protein 2; BRG1-associated factor 200; zinc ......
Location	12q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA) [ TOP ]
There is no antibody staining data.

Summary
Symbol	ARID2
Name	AT-rich interaction domain 2
Aliases	KIAA1557; DKFZp686G052; FLJ30619; BAF200; ARID domain-containing protein 2; BRG1-associated factor 200; zinc ......
Location	12q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.104	NS	24476821
BRCA	Breast invasive carcinoma	521	5.67e-27	Significant	23000897
COAD	Colon adenocarcinoma	149	0.113	NS	22810696
GBM	Glioblastoma multiforme	157	0.003	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	6.28e-15	Significant	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.0246	Significant	26536169
LGG	Brain Lower Grade Glioma	513	0.00301	Significant	26824661
LUAD	Lung adenocarcinoma	230	2.58e-05	Significant	25079552
LUSC	Lung squamous cell carcinoma	178	0.00127	Significant	22960745
OV	Ovarian serous cystadenocarcinoma	287	3.75e-10	Significant	21720365
PRAD	Prostate adenocarcinoma	333	0.00201	Significant	26544944
READ	Rectum adenocarcinoma	67	0.0143	Significant	22810696
SKCM	Skin Cutaneous Melanoma	315	0.851	NS	26091043
STAD	Stomach adenocarcinoma	277	0.000271	Significant	25079317
THCA	Thyroid carcinoma	391	0.00852	Significant	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	0.642	NS	23636398

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	0.849	0.435	NS
BRCA	Breast invasive carcinoma	1079	1.36	0.19	NS
CESC	Cervical and endocervical cancers	291	0.472	0.0344	Longer
COAD	Colon adenocarcinoma	439	0.71	0.242	NS
ESCA	Esophageal carcinoma	184	1.12	0.726	NS
GBM	Glioblastoma multiforme	158	0.532	0.0156	Longer
HNSC	Head and Neck squamous cell carcinoma	518	0.518	0.0018	Longer
KIRC	Kidney renal clear cell carcinoma	531	0.77	0.223	NS
KIRP	Kidney renal papillary cell carcinoma	287	1.25	0.565	NS
LAML	Acute Myeloid Leukemia	149	0.869	0.648	NS
LGG	Brain Lower Grade Glioma	511	1.266	0.355	NS
LIHC	Liver hepatocellular carcinoma	365	0.993	0.976	NS
LUAD	Lung adenocarcinoma	502	0.969	0.876	NS
LUSC	Lung squamous cell carcinoma	494	0.98	0.917	NS
OV	Ovarian serous cystadenocarcinoma	303	1.082	0.715	NS
PAAD	Pancreatic adenocarcinoma	177	1.008	0.977	NS
PCPG	Pheochromocytoma and Paraganglioma	179	668473109.82	0.0673	NS
PRAD	Prostate adenocarcinoma	497	0.651	0.626	NS
READ	Rectum adenocarcinoma	159	0.534	0.2	NS
SARC	Sarcoma	259	1.254	0.475	NS
SKCM	Skin Cutaneous Melanoma	459	0.986	0.941	NS
STAD	Stomach adenocarcinoma	388	1.07	0.758	NS
TGCT	Testicular Germ Cell Tumors	134	0	0.317	NS
THCA	Thyroid carcinoma	500	0.459	0.259	NS
THYM	Thymoma	119	0	0.0165	Longer
UCEC	Uterine Corpus Endometrial Carcinoma	543	1.543	0.173	NS

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	-0.155	0.0017	Lower
BRCA	Breast invasive carcinoma	1071	-0.021	0.5	NS
CESC	Cervical and endocervical cancers	167	0.017	0.824	NS
COAD	Colon adenocarcinoma	445	-0.07	0.143	NS
ESCA	Esophageal carcinoma	162	-0.017	0.835	NS
HNSC	Head and Neck squamous cell carcinoma	448	-0.05	0.296	NS
KIRC	Kidney renal clear cell carcinoma	531	-0.015	0.73	NS
KIRP	Kidney renal papillary cell carcinoma	260	0.049	0.43	NS
LIHC	Liver hepatocellular carcinoma	347	0.092	0.0857	NS
LUAD	Lung adenocarcinoma	507	0.013	0.768	NS
LUSC	Lung squamous cell carcinoma	497	0.018	0.691	NS
OV	Ovarian serous cystadenocarcinoma	302	-0.077	0.179	NS
PAAD	Pancreatic adenocarcinoma	176	-0.04	0.599	NS
READ	Rectum adenocarcinoma	156	-0.038	0.634	NS
SKCM	Skin Cutaneous Melanoma	410	-0.037	0.459	NS
STAD	Stomach adenocarcinoma	392	0.08	0.112	NS
TGCT	Testicular Germ Cell Tumors	81	-0.135	0.231	NS
THCA	Thyroid carcinoma	499	-0.08	0.0753	NS
UCEC	Uterine Corpus Endometrial Carcinoma	501	0.048	0.283	NS

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	-0.085	0.164	NS
HNSC	Head and Neck squamous cell carcinoma	498	0.114	0.011	Higher
KIRC	Kidney renal clear cell carcinoma	525	-0.066	0.13	NS
LGG	Brain Lower Grade Glioma	514	0.02	0.647	NS
LIHC	Liver hepatocellular carcinoma	366	0.109	0.0371	Higher
OV	Ovarian serous cystadenocarcinoma	296	-0.005	0.93	NS
PAAD	Pancreatic adenocarcinoma	176	-0.088	0.243	NS
STAD	Stomach adenocarcinoma	406	0.047	0.349	NS
UCEC	Uterine Corpus Endometrial Carcinoma	534	0.114	0.00826	Higher

Summary
Symbol	ARID2
Name	AT-rich interaction domain 2
Aliases	KIAA1557; DKFZp686G052; FLJ30619; BAF200; ARID domain-containing protein 2; BRG1-associated factor 200; zinc ......
Location	12q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	ARID2
Name	AT-rich interaction domain 2
Aliases	KIAA1557; DKFZp686G052; FLJ30619; BAF200; ARID domain-containing protein 2; BRG1-associated factor 200; zinc ......
Location	12q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for ARID2.

Summary
Symbol	ARID2
Name	AT-rich interaction domain 2
Aliases	KIAA1557; DKFZp686G052; FLJ30619; BAF200; ARID domain-containing protein 2; BRG1-associated factor 200; zinc ......
Location	12q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining

[ TOP ]

PMID	Cancer	Hierarchy	Gene	Relation to CR	Evidence
27035278	Hepatocellular Carcinoma	upstream	miR-155	negative regulation	Mechanistically, we identified AT-rich interactive domain 2 (ARID2) as a direct downstream target and functional mediator of miR155 in HCC cells
26169693	Hepatocellular Carcinoma	upstream	miR-208-3p; TGFβ1/miR-208-3p/ARID2 regulatory pathway	negaitve regulation; regulation	In this study, miR-208-3p was highly expressed and directly repressed ARID2 expression; Moreover, ARID2 was possibly a downstream element of transforming growth factor beta1 (TGFβ1)/miR-208-3p/ARID2 regulatory pathway