CR2Cancer

Summary
Symbol	ATF7IP
Name	activating transcription factor 7 interacting protein
Aliases	FLJ10688; p621; ATF-IP; MCAF1; ATF-interacting protein; ATF7-interacting protein; ATFa-associated modulator; ......
Location	12p13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

[ TOP ]

Domain

PF16788 ATF-interacting protein binding domain
PF16794 Fibronectin-III type domain

Function

Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3). The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3). Facilitates telomerase TERT and TERC gene expression by SP1 in cancer cells.

Classification

Class	Modification	Substrate	Product	PubMed
Histone modification write cofactor	Histone methylation	#	#	14536086

> Gene Ontology [ TOP ]
Biological Process	GO:0006304 DNA modification GO:0006305 DNA alkylation GO:0006306 DNA methylation GO:0006352 DNA-templated transcription, initiation GO:0006367 transcription initiation from RNA polymerase II promoter GO:0032259 methylation GO:0043254 regulation of protein complex assembly GO:0043414 macromolecule methylation GO:0044728 DNA methylation or demethylation GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly GO:0060260 regulation of transcription initiation from RNA polymerase II promoter GO:0065004 protein-DNA complex assembly GO:0070897 DNA-templated transcriptional preinitiation complex assembly GO:0071824 protein-DNA complex subunit organization GO:2000142 regulation of DNA-templated transcription, initiation
Molecular Function	GO:0003714 transcription corepressor activity GO:0016887 ATPase activity
Cellular Component	GO:0005667 transcription factor complex

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	R-HSA-3247509: Chromatin modifying enzymes R-HSA-4839726: Chromatin organization R-HSA-3214841: PKMTs methylate histone lysines

Summary
Symbol	ATF7IP
Name	activating transcription factor 7 interacting protein
Aliases	FLJ10688; p621; ATF-IP; MCAF1; ATF-interacting protein; ATF7-interacting protein; ATFa-associated modulator; ......
Location	12p13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM309324	c.917T>A	p.I306K	Substitution - Missense	Lung
COSM430815	c.3706G>A	p.G1236S	Substitution - Missense	Breast
COSM2002869	c.3169C>G	p.P1057A	Substitution - Missense	Skin
COSM383821	c.3752G>T	p.R1251L	Substitution - Missense	Lung
COSM1318035	c.2806_2809delACAA	p.N937fs*3	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM937510	c.2845G>T	p.A949S	Substitution - Missense	Endometrium
COSM1705206	c.2360T>C	p.V787A	Substitution - Missense	Skin
COSM4799449	c.1365A>G	p.T455T	Substitution - coding silent	Liver
COSM4040544	c.2756C>A	p.S919*	Substitution - Nonsense	Stomach
COSM2002875	c.3372C>T	p.H1124H	Substitution - coding silent	Large_intestine
COSM1360402	c.3680C>T	p.A1227V	Substitution - Missense	Large_intestine
COSM3458538	c.2123G>A	p.S708N	Substitution - Missense	Skin
COSM4040542	c.2675T>C	p.V892A	Substitution - Missense	Stomach
COSM5671025	c.676G>T	p.A226S	Substitution - Missense	Soft_tissue
COSM3458555	c.3760C>T	p.P1254S	Substitution - Missense	Skin
COSM392486	c.2802delC	p.Q935fs*6	Deletion - Frameshift	Lung
COSM4481469	c.2510C>T	p.S837F	Substitution - Missense	Skin
COSM1128636	c.1589A>G	p.K530R	Substitution - Missense	Prostate
COSM1128636	c.1589A>G	p.K530R	Substitution - Missense	Prostate
COSM395493	c.3446A>T	p.Q1149L	Substitution - Missense	Lung
COSM5636025	c.349A>G	p.I117V	Substitution - Missense	Oesophagus
COSM3458522	c.599C>T	p.S200F	Substitution - Missense	Skin
COSM4791015	c.517G>T	p.D173Y	Substitution - Missense	Liver
COSM400338	c.3735C>T	p.A1245A	Substitution - coding silent	Lung
COSM3458554	c.3407C>T	p.P1136L	Substitution - Missense	Skin
COSM4040535	c.1661G>A	p.R554Q	Substitution - Missense	Stomach
COSM937490	c.26A>C	p.K9T	Substitution - Missense	Endometrium
COSM937512	c.2941+2T>A	p.?	Unknown	Endometrium
COSM4663987	c.2249C>T	p.T750M	Substitution - Missense	Large_intestine
COSM937506	c.2210A>G	p.K737R	Substitution - Missense	Endometrium
COSM1492838	c.2941+2T>C	p.?	Unknown	Kidney
COSM4799449	c.1365A>G	p.T455T	Substitution - coding silent	Liver
COSM1360401	c.3259C>T	p.R1087W	Substitution - Missense	Large_intestine
COSM4489486	c.3482C>T	p.P1161L	Substitution - Missense	Skin
COSM3384195	c.3141G>T	p.V1047V	Substitution - coding silent	Pancreas
COSM693063	c.2479G>T	p.G827C	Substitution - Missense	Lung
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM2153895	c.1975G>T	p.D659Y	Substitution - Missense	Central_nervous_system
COSM5627442	c.33C>A	p.V11V	Substitution - coding silent	Oesophagus
COSM468077	c.2922A>G	p.E974E	Substitution - coding silent	Kidney
COSM3811570	c.568A>C	p.T190P	Substitution - Missense	Breast
COSM3724764	c.3531A>G	p.I1177M	Substitution - Missense	Lung
COSM5765813	c.4G>C	p.D2H	Substitution - Missense	Large_intestine
COSM4575253	c.2737A>C	p.I913L	Substitution - Missense	Bone
COSM1605866	c.3326A>G	p.N1109S	Substitution - Missense	Liver
COSM6000209	c.642G>A	p.P214P	Substitution - coding silent	Prostate
COSM217012	c.254_255insA	p.A86fs*13	Insertion - Frameshift	Liver
COSM5515466	c.1988G>T	p.R663I	Substitution - Missense	Biliary_tract
COSM937515	c.3665T>G	p.L1222R	Substitution - Missense	Endometrium
COSM5810080	c.1960G>T	p.E654*	Substitution - Nonsense	Liver
COSM3458546	c.2453C>T	p.S818F	Substitution - Missense	Skin
COSM1360392	c.1462C>T	p.P488S	Substitution - Missense	Large_intestine
COSM4040533	c.935A>C	p.K312T	Substitution - Missense	Stomach
COSM937508	c.2710C>T	p.R904*	Substitution - Nonsense	Endometrium
COSM5817786	c.879T>A	p.S293S	Substitution - coding silent	Liver
COSM937497	c.1536G>A	p.S512S	Substitution - coding silent	Endometrium
COSM3731905	c.2158+6delT	p.?	Unknown	Stomach
COSM4629915	c.1786C>T	p.Q596*	Substitution - Nonsense	Large_intestine
COSM5361532	c.3645G>T	p.K1215N	Substitution - Missense	Large_intestine
COSM5970619	c.3346A>G	p.T1116A	Substitution - Missense	Upper_aerodigestive_tract
COSM3811574	c.2265A>C	p.A755A	Substitution - coding silent	Breast
COSM4040552	c.3684T>C	p.C1228C	Substitution - coding silent	Stomach
COSM251292	c.255_256insA	p.A86fs*13	Insertion - Frameshift	Liver
COSM309324	c.917T>A	p.I306K	Substitution - Missense	Soft_tissue
COSM392631	c.204delG	p.E69fs*3	Deletion - Frameshift	Lung
COSM1676745	c.1660C>T	p.R554*	Substitution - Nonsense	Ovary
COSM4444403	c.3001C>T	p.R1001*	Substitution - Nonsense	Large_intestine
COSM6000209	c.642G>A	p.P214P	Substitution - coding silent	Prostate
COSM1128636	c.1589A>G	p.K530R	Substitution - Missense	Prostate
COSM1180772	c.1284_1285delCT	p.S429fs*5	Deletion - Frameshift	Large_intestine
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM5704374	c.2069+1G>T	p.?	Unknown	Haematopoietic_and_lymphoid_tissue
COSM4750243	c.1211C>T	p.A404V	Substitution - Missense	Stomach
COSM3458544	c.2182C>T	p.P728S	Substitution - Missense	Skin
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM2002877	c.3404G>A	p.R1135H	Substitution - Missense	Large_intestine
COSM4663983	c.812C>T	p.T271I	Substitution - Missense	Large_intestine
COSM4040531	c.852C>A	p.T284T	Substitution - coding silent	Stomach
COSM2002880	c.3508C>T	p.R1170C	Substitution - Missense	Large_intestine
COSM5043309	c.3777G>T	p.Q1259H	Substitution - Missense	Liver
COSM4487199	c.3153C>T	p.L1051L	Substitution - coding silent	Skin
COSM5429815	c.1487C>G	p.S496C	Substitution - Missense	Oesophagus
COSM937492	c.241C>T	p.P81S	Substitution - Missense	Endometrium
COSM3458552	c.2946C>T	p.P982P	Substitution - coding silent	Skin
COSM3792393	c.1732G>A	p.E578K	Substitution - Missense	Urinary_tract
COSM4615500	c.2314delC	p.Q773fs*11	Deletion - Frameshift	Large_intestine
COSM3954480	c.3451C>G	p.L1151V	Substitution - Missense	Lung
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM1360391	c.952_953insA	p.N320fs*4	Insertion - Frameshift	Large_intestine
COSM3739525	c.2160A>G	p.V720V	Substitution - coding silent	Liver
COSM4481469	c.2510C>T	p.S837F	Substitution - Missense	Skin
COSM693065	c.1288A>G	p.M430V	Substitution - Missense	Lung
COSM3458548	c.2522C>T	p.P841L	Substitution - Missense	Skin
COSM391869	c.1137_1138insC	p.A380fs*9	Insertion - Frameshift	Lung
COSM937511	c.2878G>T	p.G960C	Substitution - Missense	Endometrium
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM4508578	c.780C>T	p.S260S	Substitution - coding silent	Skin
COSM4663989	c.2652_2653delCA	p.T885fs*14	Deletion - Frameshift	Large_intestine
COSM5374729	c.3154C>T	p.P1052S	Substitution - Missense	Skin
COSM346342	c.3271C>T	p.P1091S	Substitution - Missense	Lung
COSM385116	c.3136C>T	p.Q1046*	Substitution - Nonsense	Lung
COSM937491	c.43C>T	p.R15*	Substitution - Nonsense	Endometrium
COSM937491	c.43C>T	p.R15*	Substitution - Nonsense	Endometrium
COSM4551151	c.51G>A	p.T17T	Substitution - coding silent	Skin
COSM4954063	c.3168T>C	p.A1056A	Substitution - coding silent	Liver
COSM4893024	c.3284T>C	p.V1095A	Substitution - Missense	Skin
COSM5361958	c.561T>C	p.G187G	Substitution - coding silent	Large_intestine
COSM3871161	c.377C>T	p.P126L	Substitution - Missense	Skin
COSM383822	c.3757G>T	p.G1253W	Substitution - Missense	Lung
COSM4842400	c.1249G>C	p.D417H	Substitution - Missense	Cervix
COSM1128636	c.1589A>G	p.K530R	Substitution - Missense	Prostate
COSM5652710	c.674C>A	p.A225D	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM937501	c.1706G>A	p.R569H	Substitution - Missense	Endometrium
COSM79522	c.465C>A	p.T155T	Substitution - coding silent	Ovary
COSM5438347	c.1043A>T	p.N348I	Substitution - Missense	Oesophagus
COSM3954476	c.1158A>G	p.I386M	Substitution - Missense	Lung
COSM3458548	c.2522C>T	p.P841L	Substitution - Missense	Skin
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM5724114	c.1749A>G	p.V583V	Substitution - coding silent	Skin
COSM5653699	c.2581G>C	p.A861P	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM30432	c.3726A>C	p.A1242A	Substitution - coding silent	Lung
COSM331743	c.2233G>A	p.G745S	Substitution - Missense	Lung
COSM3667124	c.552G>A	p.V184V	Substitution - coding silent	Liver
COSM693055	c.3719A>G	p.Y1240C	Substitution - Missense	Lung
COSM937505	c.2098G>T	p.E700*	Substitution - Nonsense	Lung
COSM3871167	c.2652C>T	p.A884A	Substitution - coding silent	Skin
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM2157050	c.3501G>A	p.K1167K	Substitution - coding silent	Central_nervous_system
COSM3666565	c.253_254insA	p.A86fs*13	Insertion - Frameshift	Liver
COSM2002823	c.953delA	p.N320fs*7	Deletion - Frameshift	Large_intestine
COSM1644411	c.1088G>A	p.R363Q	Substitution - Missense	Salivary_gland
COSM693061	c.2626C>T	p.P876S	Substitution - Missense	Lung
COSM4526730	c.1414G>T	p.E472*	Substitution - Nonsense	Skin
COSM1188440	c.2119G>T	p.E707*	Substitution - Nonsense	Lung
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM937513	c.3292C>T	p.R1098*	Substitution - Nonsense	Endometrium
COSM3667124	c.552G>A	p.V184V	Substitution - coding silent	Liver
COSM1299179	c.797C>T	p.S266F	Substitution - Missense	Urinary_tract
COSM5739583	c.3472A>G	p.T1158A	Substitution - Missense	Small_intestine
COSM385116	c.3136C>T	p.Q1046*	Substitution - Nonsense	Urinary_tract
COSM1718106	c.3398_3399CC>TT	p.P1133L	Substitution - Missense	Skin
COSM5374727	c.1720G>A	p.E574K	Substitution - Missense	Skin
COSM4750248	c.2914G>A	p.D972N	Substitution - Missense	Stomach
COSM4620957	c.1064A>G	p.D355G	Substitution - Missense	Large_intestine
COSM937498	c.1543G>T	p.E515*	Substitution - Nonsense	Endometrium
COSM937500	c.1673A>C	p.K558T	Substitution - Missense	Endometrium
COSM4422841	c.1155_1156delTA	p.S387fs*1	Deletion - Frameshift	Kidney
COSM30430	c.294T>C	p.N98N	Substitution - coding silent	Skin
COSM5724114	c.1749A>G	p.V583V	Substitution - coding silent	Skin
COSM3811576	c.2657G>T	p.R886M	Substitution - Missense	Breast
COSM430814	c.3002G>A	p.R1001Q	Substitution - Missense	Breast
COSM1605866	c.3326A>G	p.N1109S	Substitution - Missense	Liver
COSM1360391	c.952_953insA	p.N320fs*4	Insertion - Frameshift	Large_intestine
COSM4387531	c.3141_3142GA>TT	p.T1048S	Substitution - Missense	Pancreas
COSM4040529	c.647C>A	p.P216H	Substitution - Missense	Stomach
COSM1128635	c.2863-1G>T	p.?	Unknown	Prostate
COSM693054	c.3794C>G	p.S1265C	Substitution - Missense	Lung
COSM4979687	c.1706G>T	p.R569L	Substitution - Missense	Oesophagus
COSM5724114	c.1749A>G	p.V583V	Substitution - coding silent	Skin
COSM4489101	c.342C>T	p.P114P	Substitution - coding silent	Skin
COSM415936	c.2309G>T	p.G770V	Substitution - Missense	Urinary_tract
COSM5361746	c.1371C>T	p.L457L	Substitution - coding silent	Large_intestine
COSM937513	c.3292C>T	p.R1098*	Substitution - Nonsense	Biliary_tract
COSM2002818	c.438C>T	p.S146S	Substitution - coding silent	Bone
COSM937513	c.3292C>T	p.R1098*	Substitution - Nonsense	Large_intestine
COSM1159091	c.2418G>A	p.V806V	Substitution - coding silent	Pancreas
COSM3458524	c.630C>T	p.I210I	Substitution - coding silent	Skin
COSM1605865	c.2719A>G	p.I907V	Substitution - Missense	Liver
COSM1299180	c.3360C>T	p.L1120L	Substitution - coding silent	Urinary_tract
COSM5616573	c.2097G>T	p.L699L	Substitution - coding silent	Lung
COSM2002880	c.3508C>T	p.R1170C	Substitution - Missense	Large_intestine
COSM5041627	c.968A>T	p.D323V	Substitution - Missense	Liver
COSM1183887	c.475C>G	p.P159A	Substitution - Missense	Large_intestine
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM3731844	c.3229C>T	p.R1077*	Substitution - Nonsense	Stomach
COSM5429813	c.787G>A	p.E263K	Substitution - Missense	Oesophagus
COSM937503	c.1873C>T	p.R625*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM3458528	c.1197A>G	p.E399E	Substitution - coding silent	Skin
COSM398440	c.3672G>T	p.L1224F	Substitution - Missense	Lung
COSM2002818	c.438C>T	p.S146S	Substitution - coding silent	Bone
COSM3739523	c.489G>C	p.E163D	Substitution - Missense	Liver
COSM937513	c.3292C>T	p.R1098*	Substitution - Nonsense	Large_intestine
COSM937507	c.2407G>T	p.G803W	Substitution - Missense	Endometrium
COSM937503	c.1873C>T	p.R625*	Substitution - Nonsense	Endometrium
COSM5587231	c.839C>T	p.T280I	Substitution - Missense	Skin
COSM30431	c.3804G>A	p.Q1268Q	Substitution - coding silent	Lung
COSM1360391	c.952_953insA	p.N320fs*4	Insertion - Frameshift	Large_intestine
COSM1578716	c.1855T>C	p.L619L	Substitution - coding silent	Meninges
COSM693062	c.2614G>C	p.V872L	Substitution - Missense	Lung
COSM6014857	c.1930G>T	p.A644S	Substitution - Missense	Skin
COSM693066	c.382G>T	p.E128*	Substitution - Nonsense	Lung
COSM3737346	c.2987C>T	p.S996F	Substitution - Missense	Soft_tissue
COSM3871163	c.647C>T	p.P216L	Substitution - Missense	Skin
COSM937509	c.2711G>A	p.R904Q	Substitution - Missense	Endometrium
COSM1183887	c.475C>G	p.P159A	Substitution - Missense	Large_intestine
COSM937508	c.2710C>T	p.R904*	Substitution - Nonsense	Cervix
COSM28371	c.1114G>T	p.E372*	Substitution - Nonsense	Lung
COSM4040550	c.3470G>A	p.S1157N	Substitution - Missense	Stomach
COSM2002841	c.1827G>A	p.A609A	Substitution - coding silent	Stomach
COSM937504	c.1902G>A	p.R634R	Substitution - coding silent	Endometrium
COSM3416663	c.1819T>G	p.L607V	Substitution - Missense	Large_intestine
COSM4040538	c.2183C>A	p.P728H	Substitution - Missense	Stomach
COSM459600	c.572C>G	p.S191C	Substitution - Missense	Cervix
COSM1476373	c.2767G>A	p.E923K	Substitution - Missense	Breast
COSM937496	c.1468G>T	p.E490*	Substitution - Nonsense	Endometrium
COSM693057	c.3225C>A	p.P1075P	Substitution - coding silent	Lung
COSM3986785	c.626C>G	p.P209R	Substitution - Missense	Kidney
COSM5361532	c.3645G>T	p.K1215N	Substitution - Missense	Large_intestine
COSM3731844	c.3229C>T	p.R1077*	Substitution - Nonsense	Stomach
COSM1605865	c.2719A>G	p.I907V	Substitution - Missense	Liver
COSM693059	c.3118A>G	p.T1040A	Substitution - Missense	Lung
COSM3710581	c.665G>C	p.G222A	Substitution - Missense	Upper_aerodigestive_tract
COSM4663985	c.1160C>G	p.S387C	Substitution - Missense	Large_intestine
COSM390049	c.979G>T	p.E327*	Substitution - Nonsense	Lung
COSM391904	c.1933delA	p.K645fs*2	Deletion - Frameshift	Lung
COSM4975663	c.3307A>G	p.T1103A	Substitution - Missense	Oesophagus
COSM4040546	c.2941G>T	p.D981Y	Substitution - Missense	Stomach
COSM3737346	c.2987C>T	p.S996F	Substitution - Missense	Soft_tissue
COSM547513	c.2232G>T	p.S744S	Substitution - coding silent	Prostate
COSM251292	c.255_256insA	p.A86fs*13	Insertion - Frameshift	Liver
COSM1676745	c.1660C>T	p.R554*	Substitution - Nonsense	Large_intestine
COSM6000209	c.642G>A	p.P214P	Substitution - coding silent	Prostate
COSM468075	c.1392T>G	p.N464K	Substitution - Missense	Kidney
COSM2157050	c.3501G>A	p.K1167K	Substitution - coding silent	Central_nervous_system
COSM4965220	c.3331C>A	p.L1111I	Substitution - Missense	Pancreas
COSM1159091	c.2418G>A	p.V806V	Substitution - coding silent	Pancreas
COSM5580291	c.1355T>C	p.F452S	Substitution - Missense	Skin
COSM4954063	c.3168T>C	p.A1056A	Substitution - coding silent	Liver
COSM937493	c.482C>G	p.S161C	Substitution - Missense	Endometrium
COSM279027	c.1231A>G	p.N411D	Substitution - Missense	Large_intestine
COSM1746864	c.3198T>A	p.T1066T	Substitution - coding silent	Urinary_tract
COSM3458550	c.2562T>A	p.S854R	Substitution - Missense	Skin
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM28371	c.1114G>T	p.E372*	Substitution - Nonsense	Lung
COSM1128634	c.3357G>C	p.Q1119H	Substitution - Missense	Prostate
COSM1733315	c.3541T>C	p.W1181R	Substitution - Missense	Pancreas
COSM3954478	c.2291C>A	p.T764N	Substitution - Missense	Lung
COSM1360391	c.952_953insA	p.N320fs*4	Insertion - Frameshift	Large_intestine
COSM2153895	c.1975G>T	p.D659Y	Substitution - Missense	Central_nervous_system
COSM4166113	c.2745A>C	p.A915A	Substitution - coding silent	Kidney
COSM5347409	c.2814_2818delAACAA	p.K938fs*7	Deletion - Frameshift	Liver
COSM5442808	c.2941+1G>C	p.?	Unknown	Oesophagus
COSM4040551	c.3647T>C	p.I1216T	Substitution - Missense	Stomach
COSM1128636	c.1589A>G	p.K530R	Substitution - Missense	Prostate
COSM1183886	c.137G>A	p.G46D	Substitution - Missense	Large_intestine
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM5480090	c.3704C>T	p.S1235F	Substitution - Missense	Large_intestine
COSM468074	c.1061C>T	p.T354I	Substitution - Missense	Kidney
COSM236698	c.3634C>T	p.Q1212*	Substitution - Nonsense	Prostate
COSM5478086	c.2462G>A	p.S821N	Substitution - Missense	Large_intestine
COSM693060	c.2878G>A	p.G960S	Substitution - Missense	Lung
COSM5514427	c.2808_2809insA	p.N937fs*10	Insertion - Frameshift	Biliary_tract
COSM1128636	c.1589A>G	p.K530R	Substitution - Missense	Prostate
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM937499	c.1593T>C	p.P531P	Substitution - coding silent	Endometrium
COSM5469939	c.3254C>T	p.A1085V	Substitution - Missense	Large_intestine
COSM2152542	c.1665A>T	p.K555N	Substitution - Missense	Central_nervous_system
COSM3458534	c.1473C>T	p.A491A	Substitution - coding silent	Skin
COSM1676745	c.1660C>T	p.R554*	Substitution - Nonsense	Large_intestine
COSM2152542	c.1665A>T	p.K555N	Substitution - Missense	Central_nervous_system
COSM4166111	c.1856T>C	p.L619S	Substitution - Missense	Kidney
COSM4040540	c.2448C>A	p.F816L	Substitution - Missense	Stomach
COSM4040549	c.3390T>C	p.H1130H	Substitution - coding silent	Stomach
COSM2002823	c.953delA	p.N320fs*7	Deletion - Frameshift	Large_intestine
COSM2002845	c.1983G>T	p.K661N	Substitution - Missense	Large_intestine
COSM3458526	c.1195G>A	p.E399K	Substitution - Missense	Skin
COSM4040525	c.361C>T	p.P121S	Substitution - Missense	Stomach
COSM1605867	c.3336C>A	p.T1112T	Substitution - coding silent	Liver
COSM5629966	c.2231C>T	p.S744L	Substitution - Missense	Oesophagus
COSM307642	c.713A>G	p.D238G	Substitution - Missense	Kidney
COSM5916156	c.1744C>T	p.Q582*	Substitution - Nonsense	Skin
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM937494	c.676G>A	p.A226T	Substitution - Missense	Endometrium
COSM3811572	c.2140C>T	p.Q714*	Substitution - Nonsense	Breast
COSM6014859	c.3394-6C>G	p.?	Unknown	Skin
COSM3739527	c.2558C>T	p.P853L	Substitution - Missense	Liver
COSM1183885	c.2087G>A	p.R696K	Substitution - Missense	Large_intestine
COSM1718106	c.3398_3399CC>TT	p.P1133L	Substitution - Missense	Skin
COSM1245635	c.1764A>T	p.K588N	Substitution - Missense	Oesophagus
COSM3871165	c.902C>T	p.P301L	Substitution - Missense	Skin
COSM4490384	c.3630C>T	p.P1210P	Substitution - coding silent	Skin
COSM693064	c.2132C>A	p.P711Q	Substitution - Missense	Lung
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM3710581	c.665G>C	p.G222A	Substitution - Missense	Upper_aerodigestive_tract
COSM937514	c.3662C>T	p.A1221V	Substitution - Missense	Endometrium
COSM5724114	c.1749A>G	p.V583V	Substitution - coding silent	Skin
COSM937491	c.43C>T	p.R15*	Substitution - Nonsense	Endometrium
COSM4663981	c.608A>G	p.D203G	Substitution - Missense	Large_intestine
COSM5438347	c.1043A>T	p.N348I	Substitution - Missense	Oesophagus
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM272362	c.2247A>G	p.A749A	Substitution - coding silent	Large_intestine
COSM4791015	c.517G>T	p.D173Y	Substitution - Missense	Liver
COSM5368979	c.1108A>T	p.K370*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM468076	c.2287G>C	p.A763P	Substitution - Missense	Kidney
COSM1705205	c.937G>A	p.D313N	Substitution - Missense	Skin
COSM3416667	c.3293G>A	p.R1098Q	Substitution - Missense	Large_intestine
COSM3416665	c.2158+2T>C	p.?	Unknown	Large_intestine
COSM3871169	c.3772C>T	p.P1258S	Substitution - Missense	Skin
COSM937505	c.2098G>T	p.E700*	Substitution - Nonsense	Endometrium
COSM5726012	c.3225C>T	p.P1075P	Substitution - coding silent	Skin
COSM4528347	c.152G>A	p.G51E	Substitution - Missense	Skin
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM3458530	c.1227G>A	p.T409T	Substitution - coding silent	Skin
COSM2002848	c.2089C>T	p.Q697*	Substitution - Nonsense	Large_intestine
COSM1183887	c.475C>G	p.P159A	Substitution - Missense	Biliary_tract
COSM4040548	c.3375A>C	p.R1125R	Substitution - coding silent	Stomach
COSM3968116	c.58G>A	p.V20M	Substitution - Missense	Central_nervous_system
COSM1733305	c.1858G>A	p.A620T	Substitution - Missense	Pancreas
COSM3968118	c.3258T>C	p.V1086V	Substitution - coding silent	Central_nervous_system
COSM3458540	c.2146C>G	p.P716A	Substitution - Missense	Skin
COSM2002844	c.1915C>T	p.L639F	Substitution - Missense	Large_intestine
COSM1746864	c.3198T>A	p.T1066T	Substitution - coding silent	Urinary_tract
COSM4843573	c.2663C>T	p.S888F	Substitution - Missense	Cervix
COSM344127	c.424G>T	p.G142*	Substitution - Nonsense	Lung
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM3458536	c.1535C>T	p.S512L	Substitution - Missense	Skin
COSM937496	c.1468G>T	p.E490*	Substitution - Nonsense	Endometrium
COSM693058	c.3145A>C	p.T1049P	Substitution - Missense	Lung
COSM3458532	c.1433C>T	p.P478L	Substitution - Missense	Skin
COSM4575255	c.3281G>C	p.S1094T	Substitution - Missense	Bone
COSM4590784	c.2647C>A	p.Q883K	Substitution - Missense	Upper_aerodigestive_tract
COSM693056	c.3694C>G	p.Q1232E	Substitution - Missense	Lung
COSM937502	c.1835G>A	p.C612Y	Substitution - Missense	Endometrium
COSM937495	c.1287_1288delTA	p.M430fs*4	Deletion - Frameshift	Endometrium
COSM4889753	c.3566G>T	p.S1189I	Substitution - Missense	Upper_aerodigestive_tract
COSM1159091	c.2418G>A	p.V806V	Substitution - coding silent	Pancreas
COSM3458542	c.2166A>G	p.S722S	Substitution - coding silent	Skin
COSM3986787	c.2553C>T	p.P851P	Substitution - coding silent	Kidney
COSM1676744	c.1087C>T	p.R363*	Substitution - Nonsense	Large_intestine
COSM4040527	c.491C>T	p.P164L	Substitution - Missense	Stomach
COSM937513	c.3292C>T	p.R1098*	Substitution - Nonsense	Endometrium
COSM3384197	c.3142A>T	p.T1048S	Substitution - Missense	Pancreas

> Text Mining based Variations [ TOP ]
There is no record for ATF7IP.

Summary
Symbol	ATF7IP
Name	activating transcription factor 7 interacting protein
Aliases	FLJ10688; p621; ATF-IP; MCAF1; ATF-interacting protein; ATF7-interacting protein; ATFa-associated modulator; ......
Location	12p13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

[ TOP ]

Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant
Q6VMQ6	57	S	Phosphoserine	-	No	None detected
Q6VMQ6	113	S	Phosphoserine	-	No	None detected
Q6VMQ6	118	T	Phosphothreonine	-	No	None detected
Q6VMQ6	445	S	Phosphoserine	-	No	None detected
Q6VMQ6	473	S	Phosphoserine	-	No	None detected
Q6VMQ6	474	S	Phosphoserine	-	No	None detected
Q6VMQ6	477	S	Phosphoserine	-	No	None detected
Q6VMQ6	479	S	Phosphoserine	-	No	None detected
Q6VMQ6	496	S	Phosphoserine	-	No	None detected
Q6VMQ6	559	S	Phosphoserine	-	No	None detected
Q6VMQ6	673	S	Phosphoserine	-	No	None detected
Q6VMQ6	899	S	Phosphoserine	-	No	None detected

Summary
Symbol	ATF7IP
Name	activating transcription factor 7 interacting protein
Aliases	FLJ10688; p621; ATF-IP; MCAF1; ATF-interacting protein; ATF7-interacting protein; ATFa-associated modulator; ......
Location	12p13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	5.221	5.035	-0.006	0.98	NS
BRCA	Breast invasive carcinoma	112	1100	6.091	5.868	-0.205	0.0092	NS
CESC	Cervical and endocervical cancers	3	306	4.807	4.91	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	4.881	5	0.15	0.0899	NS
ESCA	Esophageal carcinoma	11	185	5.945	6.525	0.563	0.0105	NS
GBM	Glioblastoma multiforme	5	166	4.703	5.155	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	5.587	5.755	0.169	0.196	NS
KIRC	Kidney renal clear cell carcinoma	72	534	5.657	5.731	0.002	0.977	NS
KIRP	Kidney renal papillary cell carcinoma	32	291	5.324	5.005	-0.191	0.25	NS
LAML	Acute Myeloid Leukemia	0	173	NA	7.412	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	5.776	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	4.025	3.853	-0.095	0.4	NS
LUAD	Lung adenocarcinoma	59	517	5.171	5.397	0.336	9.97e-05	NS
LUSC	Lung squamous cell carcinoma	51	501	5.278	5.756	0.535	2.95e-09	NS
OV	Ovarian serous cystadenocarcinoma	0	307	NA	6.154	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	5.078	4.893	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	4.343	4.43	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	5.291	4.67	-0.548	3.84e-06	NS
READ	Rectum adenocarcinoma	10	167	4.968	5.144	0.162	0.424	NS
SARC	Sarcoma	2	263	4.112	4.964	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	5.299	5.381	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	5.864	6.19	0.154	0.161	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	6.011	NA	NA	NA
THCA	Thyroid carcinoma	59	509	5.796	5.638	-0.106	0.238	NS
THYM	Thymoma	2	120	5.895	5.076	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	4.765	5.088	0.261	0.036	NS

> Cancer Cell Line Encyclopedia (CCLE)

[ TOP ]

Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	9.7
Autonomic ganglia	CHP212	8.6
Autonomic ganglia	IMR32	9.7
Autonomic ganglia	KELLY	9.4
Autonomic ganglia	KPNRTBM1	9.3
Autonomic ganglia	KPNSI9S	9.1
Autonomic ganglia	KPNYN	9.3
Autonomic ganglia	MHHNB11	9.2
Autonomic ganglia	NB1	9.4
Autonomic ganglia	NH6	9
Autonomic ganglia	SHSY5Y	9
Autonomic ganglia	SIMA	9.1
Autonomic ganglia	SKNAS	9
Autonomic ganglia	SKNBE2	9.6
Autonomic ganglia	SKNDZ	9.2
Autonomic ganglia	SKNFI	9.1
Autonomic ganglia	SKNSH	8.4
Biliary tract	HUCCT1	9.6
Biliary tract	HUH28	9
Biliary tract	SNU1079	7.4
Biliary tract	SNU1196	8.6
Biliary tract	SNU245	9.4
Biliary tract	SNU308	9.7
Biliary tract	SNU478	8.7
Bone	143B	8.2
Bone	A673	9.8
Bone	CADOES1	9.6
Bone	CAL78	9.6
Bone	G292CLONEA141B1	8.9
Bone	HOS	8.9
Bone	HS706T	9.5
Bone	HS737T	9.5
Bone	HS819T	9.2
Bone	HS821T	9.3
Bone	HS822T	8.9
Bone	HS863T	8.6
Bone	HS870T	8.8
Bone	HS888T	9.3
Bone	MG63	9
Bone	MHHES1	9.5
Bone	OUMS27	10.1
Bone	RDES	9.2
Bone	SJSA1	8.1
Bone	SKES1	9.5
Bone	SKNMC	9.2
Bone	SW1353	8.7
Bone	T173	9.2
Bone	TC71	9.5
Bone	U2OS	9.6
Breast	AU565	8.7
Breast	BT20	9.9
Breast	BT474	9.3
Breast	BT483	9.8
Breast	BT549	8.7
Breast	CAL120	10.4
Breast	CAL148	8.9
Breast	CAL51	9.5
Breast	CAL851	9.6
Breast	CAMA1	8.9
Breast	DU4475	8
Breast	EFM192A	8.8
Breast	EFM19	9.5
Breast	EVSAT	8.7
Breast	HCC1143	9.5
Breast	HCC1187	9.8
Breast	HCC1395	9.7
Breast	HCC1419	9.7
Breast	HCC1428	9.6
Breast	HCC1500	8.4
Breast	HCC1569	9.6
Breast	HCC1599	6.8
Breast	HCC1806	10.2
Breast	HCC1937	10.4
Breast	HCC1954	9.4
Breast	HCC202	9.3
Breast	HCC2157	9.6
Breast	HCC2218	8.5
Breast	HCC38	9.1
Breast	HCC70	9.9
Breast	HDQP1	9.2
Breast	HMC18	9.6
Breast	HS274T	9.2
Breast	HS281T	9.3
Breast	HS343T	9.2
Breast	HS578T	8.8
Breast	HS606T	8.8
Breast	HS739T	8.9
Breast	HS742T	8.3
Breast	JIMT1	9.9
Breast	KPL1	9.2
Breast	MCF7	9.2
Breast	MDAMB134VI	8.8
Breast	MDAMB157	9.2
Breast	MDAMB175VII	8.7
Breast	MDAMB231	9.4
Breast	MDAMB361	10
Breast	MDAMB415	9.6
Breast	MDAMB436	9.4
Breast	MDAMB453	9.4
Breast	MDAMB468	4
Breast	SKBR3	8.7
Breast	T47D	9
Breast	UACC812	7.8
Breast	UACC893	9.5
Breast	YMB1	8.5
Breast	ZR751	8.1
Breast	ZR7530	9.5
Central nervous system	1321N1	10.1
Central nervous system	42MGBA	9.4
Central nervous system	8MGBA	8.6
Central nervous system	A172	7.8
Central nervous system	AM38	9.7
Central nervous system	BECKER	9.3
Central nervous system	CAS1	10.3
Central nervous system	CCFSTTG1	9.5
Central nervous system	D283MED	9.6
Central nervous system	D341MED	9.5
Central nervous system	DAOY	9
Central nervous system	DBTRG05MG	9
Central nervous system	DKMG	8.5
Central nervous system	GAMG	9.1
Central nervous system	GB1	9.6
Central nervous system	GI1	8.5
Central nervous system	GMS10	9.9
Central nervous system	GOS3	9.3
Central nervous system	H4	10
Central nervous system	HS683	9.2
Central nervous system	KALS1	9.5
Central nervous system	KG1C	10
Central nervous system	KNS42	8.7
Central nervous system	KNS60	9
Central nervous system	KNS81	8.4
Central nervous system	KS1	8.2
Central nervous system	LN18	10
Central nervous system	LN229	9.1
Central nervous system	M059K	9
Central nervous system	MOGGCCM	9.1
Central nervous system	MOGGUVW	9.9
Central nervous system	NMCG1	8.6
Central nervous system	ONS76	9.8
Central nervous system	SF126	9.8
Central nervous system	SF295	9
Central nervous system	SNB19	9.6
Central nervous system	SNU1105	9
Central nervous system	SNU201	9.7
Central nervous system	SNU466	8.9
Central nervous system	SNU489	9
Central nervous system	SNU626	8.5
Central nervous system	SNU738	8.7
Central nervous system	SW1088	9.7
Central nervous system	SW1783	9.1
Central nervous system	T98G	8.8
Central nervous system	TM31	9.7
Central nervous system	U118MG	9.8
Central nervous system	U138MG	8.9
Central nervous system	U251MG	8.8
Central nervous system	U87MG	8.5
Central nervous system	YH13	9.5
Central nervous system	YKG1	8.7
Endometrium	AN3CA	10.2
Endometrium	COLO684	8.7
Endometrium	EFE184	9.4
Endometrium	EN	9.1
Endometrium	ESS1	8.3
Endometrium	HEC108	9.5
Endometrium	HEC151	8.7
Endometrium	HEC1A	9.2
Endometrium	HEC1B	9.4
Endometrium	HEC251	9
Endometrium	HEC265	7.4
Endometrium	HEC50B	8.7
Endometrium	HEC59	9.2
Endometrium	HEC6	8.4
Endometrium	ISHIKAWAHERAKLIO02ER	10.1
Endometrium	JHUEM1	9.5
Endometrium	JHUEM2	9.2
Endometrium	JHUEM3	9.4
Endometrium	KLE	9.1
Endometrium	MFE280	9.3
Endometrium	MFE296	10.5
Endometrium	MFE319	9.2
Endometrium	RL952	9.6
Endometrium	SNGM	8.3
Endometrium	SNU1077	9.3
Endometrium	SNU685	7.9
Endometrium	TEN	10
Haematopoietic and lymphoid	697	9.8
Haematopoietic and lymphoid	A3KAW	8.7
Haematopoietic and lymphoid	A4FUK	9.7
Haematopoietic and lymphoid	ALLSIL	9
Haematopoietic and lymphoid	AML193	8.8
Haematopoietic and lymphoid	AMO1	9.7
Haematopoietic and lymphoid	BCP1	9.4
Haematopoietic and lymphoid	BDCM	9.8
Haematopoietic and lymphoid	BL41	9.1
Haematopoietic and lymphoid	BL70	9.1
Haematopoietic and lymphoid	BV173	7.3
Haematopoietic and lymphoid	CA46	9.6
Haematopoietic and lymphoid	CI1	9.5
Haematopoietic and lymphoid	CMK115	9.1
Haematopoietic and lymphoid	CMK86	8.1
Haematopoietic and lymphoid	CMK	9.3
Haematopoietic and lymphoid	CMLT1	9.8
Haematopoietic and lymphoid	COLO775	8.6
Haematopoietic and lymphoid	DAUDI	9.6
Haematopoietic and lymphoid	DB	9.9
Haematopoietic and lymphoid	DEL	8.5
Haematopoietic and lymphoid	DND41	8.4
Haematopoietic and lymphoid	DOHH2	9
Haematopoietic and lymphoid	EB1	9.7
Haematopoietic and lymphoid	EB2	9
Haematopoietic and lymphoid	EHEB	9.9
Haematopoietic and lymphoid	EJM	9.5
Haematopoietic and lymphoid	EM2	9
Haematopoietic and lymphoid	EOL1	8.8
Haematopoietic and lymphoid	F36P	9.1
Haematopoietic and lymphoid	GA10	8.9
Haematopoietic and lymphoid	GDM1	8.8
Haematopoietic and lymphoid	GRANTA519	10.2
Haematopoietic and lymphoid	HDLM2	9.5
Haematopoietic and lymphoid	HDMYZ	9
Haematopoietic and lymphoid	HEL9217	9.5
Haematopoietic and lymphoid	HEL	9
Haematopoietic and lymphoid	HH	9.3
Haematopoietic and lymphoid	HL60	9.1
Haematopoietic and lymphoid	HPBALL	9
Haematopoietic and lymphoid	HS604T	9
Haematopoietic and lymphoid	HS611T	9.5
Haematopoietic and lymphoid	HS616T	9.1
Haematopoietic and lymphoid	HS751T	8.5
Haematopoietic and lymphoid	HT	9.3
Haematopoietic and lymphoid	HTK	7.1
Haematopoietic and lymphoid	HUNS1	9.2
Haematopoietic and lymphoid	HUT102	9.6
Haematopoietic and lymphoid	HUT78	9.8
Haematopoietic and lymphoid	JEKO1	8.9
Haematopoietic and lymphoid	JK1	9.4
Haematopoietic and lymphoid	JM1	8.7
Haematopoietic and lymphoid	JURKAT	8.2
Haematopoietic and lymphoid	JURLMK1	8.7
Haematopoietic and lymphoid	JVM2	9.7
Haematopoietic and lymphoid	JVM3	10
Haematopoietic and lymphoid	K562	8
Haematopoietic and lymphoid	KARPAS299	8.9
Haematopoietic and lymphoid	KARPAS422	9.8
Haematopoietic and lymphoid	KARPAS620	9.1
Haematopoietic and lymphoid	KASUMI1	9.1
Haematopoietic and lymphoid	KASUMI2	9.3
Haematopoietic and lymphoid	KASUMI6	8.5
Haematopoietic and lymphoid	KCL22	8.8
Haematopoietic and lymphoid	KE37	9.8
Haematopoietic and lymphoid	KE97	9.1
Haematopoietic and lymphoid	KG1	9.1
Haematopoietic and lymphoid	KHM1B	8.2
Haematopoietic and lymphoid	KIJK	8.5
Haematopoietic and lymphoid	KMH2	9.5
Haematopoietic and lymphoid	KMM1	9.6
Haematopoietic and lymphoid	KMS11	9.1
Haematopoietic and lymphoid	KMS12BM	9.5
Haematopoietic and lymphoid	KMS18	9.3
Haematopoietic and lymphoid	KMS20	9.1
Haematopoietic and lymphoid	KMS21BM	8.8
Haematopoietic and lymphoid	KMS26	9
Haematopoietic and lymphoid	KMS27	9
Haematopoietic and lymphoid	KMS28BM	9.6
Haematopoietic and lymphoid	KMS34	9.9
Haematopoietic and lymphoid	KO52	9.4
Haematopoietic and lymphoid	KOPN8	8.7
Haematopoietic and lymphoid	KU812	9
Haematopoietic and lymphoid	KYO1	9
Haematopoietic and lymphoid	L1236	9.3
Haematopoietic and lymphoid	L363	8.6
Haematopoietic and lymphoid	L428	10.1
Haematopoietic and lymphoid	L540	8.3
Haematopoietic and lymphoid	LAMA84	9.2
Haematopoietic and lymphoid	LOUCY	10.2
Haematopoietic and lymphoid	LP1	10.3
Haematopoietic and lymphoid	M07E	9.2
Haematopoietic and lymphoid	MC116	9.6
Haematopoietic and lymphoid	ME1	9.1
Haematopoietic and lymphoid	MEC1	9.7
Haematopoietic and lymphoid	MEC2	10
Haematopoietic and lymphoid	MEG01	10.3
Haematopoietic and lymphoid	MHHCALL2	9.2
Haematopoietic and lymphoid	MHHCALL3	9.5
Haematopoietic and lymphoid	MHHCALL4	9.3
Haematopoietic and lymphoid	MINO	9.5
Haematopoietic and lymphoid	MJ	9.7
Haematopoietic and lymphoid	MM1S	8.9
Haematopoietic and lymphoid	MOLM13	8.1
Haematopoietic and lymphoid	MOLM16	10
Haematopoietic and lymphoid	MOLM6	8.8
Haematopoietic and lymphoid	MOLP2	8.8
Haematopoietic and lymphoid	MOLP8	9.5
Haematopoietic and lymphoid	MOLT13	9.1
Haematopoietic and lymphoid	MOLT16	10.2
Haematopoietic and lymphoid	MOLT4	9
Haematopoietic and lymphoid	MONOMAC1	8.1
Haematopoietic and lymphoid	MONOMAC6	8
Haematopoietic and lymphoid	MOTN1	9.9
Haematopoietic and lymphoid	MUTZ5	9.9
Haematopoietic and lymphoid	MV411	8.6
Haematopoietic and lymphoid	NALM19	9.7
Haematopoietic and lymphoid	NALM1	9.4
Haematopoietic and lymphoid	NALM6	9.3
Haematopoietic and lymphoid	NAMALWA	8.8
Haematopoietic and lymphoid	NB4	9.3
Haematopoietic and lymphoid	NCIH929	8.1
Haematopoietic and lymphoid	NCO2	9.4
Haematopoietic and lymphoid	NOMO1	8.9
Haematopoietic and lymphoid	NUDHL1	9.3
Haematopoietic and lymphoid	NUDUL1	10.1
Haematopoietic and lymphoid	OCIAML2	9.2
Haematopoietic and lymphoid	OCIAML3	8.3
Haematopoietic and lymphoid	OCIAML5	9
Haematopoietic and lymphoid	OCILY10	9.7
Haematopoietic and lymphoid	OCILY19	9.1
Haematopoietic and lymphoid	OCILY3	9.6
Haematopoietic and lymphoid	OCIM1	10.5
Haematopoietic and lymphoid	OPM2	10.3
Haematopoietic and lymphoid	P12ICHIKAWA	9.1
Haematopoietic and lymphoid	P31FUJ	8.3
Haematopoietic and lymphoid	P3HR1	9.6
Haematopoietic and lymphoid	PCM6	9.4
Haematopoietic and lymphoid	PEER	8.9
Haematopoietic and lymphoid	PF382	9.2
Haematopoietic and lymphoid	PFEIFFER	10.1
Haematopoietic and lymphoid	PL21	8.4
Haematopoietic and lymphoid	RAJI	9.4
Haematopoietic and lymphoid	RCHACV	9.1
Haematopoietic and lymphoid	REC1	10.2
Haematopoietic and lymphoid	REH	9.3
Haematopoietic and lymphoid	RI1	9.7
Haematopoietic and lymphoid	RL	9.5
Haematopoietic and lymphoid	RPMI8226	9.2
Haematopoietic and lymphoid	RPMI8402	9.8
Haematopoietic and lymphoid	RS411	9.5
Haematopoietic and lymphoid	SEM	9.5
Haematopoietic and lymphoid	SET2	10
Haematopoietic and lymphoid	SIGM5	8.5
Haematopoietic and lymphoid	SKM1	8.1
Haematopoietic and lymphoid	SKMM2	8.8
Haematopoietic and lymphoid	SR786	8.9
Haematopoietic and lymphoid	ST486	8.9
Haematopoietic and lymphoid	SUDHL10	8.4
Haematopoietic and lymphoid	SUDHL1	8.3
Haematopoietic and lymphoid	SUDHL4	9.3
Haematopoietic and lymphoid	SUDHL5	9.8
Haematopoietic and lymphoid	SUDHL6	9.7
Haematopoietic and lymphoid	SUDHL8	9.4
Haematopoietic and lymphoid	SUPB15	9.2
Haematopoietic and lymphoid	SUPHD1	9.9
Haematopoietic and lymphoid	SUPM2	9
Haematopoietic and lymphoid	SUPT11	9.2
Haematopoietic and lymphoid	SUPT1	9.4
Haematopoietic and lymphoid	TALL1	8.6
Haematopoietic and lymphoid	TF1	9.3
Haematopoietic and lymphoid	THP1	9
Haematopoietic and lymphoid	TO175T	9.1
Haematopoietic and lymphoid	TOLEDO	9
Haematopoietic and lymphoid	U266B1	8.4
Haematopoietic and lymphoid	U937	8
Haematopoietic and lymphoid	UT7	10
Haematopoietic and lymphoid	WSUDLCL2	9.5
Kidney	769P	9.2
Kidney	786O	8.7
Kidney	A498	7.9
Kidney	A704	9
Kidney	ACHN	8.7
Kidney	BFTC909	8.9
Kidney	CAKI1	8.7
Kidney	CAKI2	9
Kidney	CAL54	8.7
Kidney	KMRC1	8.3
Kidney	KMRC20	9.5
Kidney	KMRC2	8.5
Kidney	KMRC3	9.1
Kidney	OSRC2	8.8
Kidney	RCC10RGB	9.3
Kidney	SNU1272	8.5
Kidney	SNU349	9.4
Kidney	TUHR10TKB	8.8
Kidney	TUHR14TKB	9.8
Kidney	TUHR4TKB	8.8
Kidney	VMRCRCW	9.7
Kidney	VMRCRCZ	9.9
Large intestine	C2BBE1	9.3
Large intestine	CCK81	8.9
Large intestine	CL11	9.3
Large intestine	CL14	10.3
Large intestine	CL34	9.4
Large intestine	CL40	9.4
Large intestine	COLO205	8.6
Large intestine	COLO320	9.2
Large intestine	COLO678	8.2
Large intestine	CW2	9.5
Large intestine	DLD1	8.9
Large intestine	GP2D	8.8
Large intestine	HCC56	8.7
Large intestine	HCT116	8.7
Large intestine	HCT15	8.6
Large intestine	HS675T	8.7
Large intestine	HS698T	9.2
Large intestine	HT115	9.4
Large intestine	HT29	8.2
Large intestine	HT55	9.1
Large intestine	KM12	8.2
Large intestine	LOVO	9
Large intestine	LS1034	9.6
Large intestine	LS123	10.3
Large intestine	LS180	8.8
Large intestine	LS411N	10.3
Large intestine	LS513	7.7
Large intestine	MDST8	8.6
Large intestine	NCIH508	7.9
Large intestine	NCIH716	9.9
Large intestine	NCIH747	9.6
Large intestine	OUMS23	10.2
Large intestine	RCM1	8.4
Large intestine	RKO	8.4
Large intestine	SKCO1	8.3
Large intestine	SNU1040	8.6
Large intestine	SNU1197	9.1
Large intestine	SNU175	8.2
Large intestine	SNU283	8.8
Large intestine	SNU407	9.1
Large intestine	SNU503	9.1
Large intestine	SNU61	9.3
Large intestine	SNU81	8.8
Large intestine	SNUC1	8.7
Large intestine	SNUC2A	9.4
Large intestine	SNUC4	9.1
Large intestine	SNUC5	9.1
Large intestine	SW1116	9.2
Large intestine	SW1417	9.3
Large intestine	SW1463	8.9
Large intestine	SW403	8.5
Large intestine	SW480	9
Large intestine	SW48	8.5
Large intestine	SW620	9.6
Large intestine	SW837	9.4
Large intestine	SW948	8.6
Large intestine	T84	10
Liver	ALEXANDERCELLS	8.6
Liver	C3A	8
Liver	HEP3B217	9.2
Liver	HEPG2	7.2
Liver	HLE	9.7
Liver	HLF	9.6
Liver	HUH1	8.7
Liver	HUH6	9.6
Liver	HUH7	9.5
Liver	JHH1	9.2
Liver	JHH2	8.8
Liver	JHH4	8.3
Liver	JHH5	9.9
Liver	JHH6	8.9
Liver	JHH7	9.7
Liver	LI7	8.9
Liver	PLCPRF5	8.7
Liver	SKHEP1	8.6
Liver	SNU182	8.5
Liver	SNU387	8.1
Liver	SNU398	9.7
Liver	SNU423	8.8
Liver	SNU449	9.3
Liver	SNU475	9.1
Liver	SNU761	8.5
Liver	SNU878	8.8
Liver	SNU886	8.4
Lung	A549	8.3
Lung	ABC1	8.9
Lung	BEN	8.2
Lung	CAL12T	8.3
Lung	CALU1	9.8
Lung	CALU3	9.2
Lung	CALU6	10.2
Lung	CHAGOK1	8.8
Lung	COLO668	8.6
Lung	COLO699	8.5
Lung	CORL105	8.4
Lung	CORL23	9.7
Lung	CORL24	9.1
Lung	CORL279	9.3
Lung	CORL311	8.5
Lung	CORL47	8.4
Lung	CORL51	8.6
Lung	CORL88	10.3
Lung	CORL95	8.4
Lung	CPCN	9.5
Lung	DMS114	10.2
Lung	DMS153	9.3
Lung	DMS273	9.7
Lung	DMS454	8.7
Lung	DMS53	9.7
Lung	DMS79	9.8
Lung	DV90	8.3
Lung	EBC1	9.1
Lung	EPLC272H	9.6
Lung	HARA	8.9
Lung	HCC1171	8.7
Lung	HCC1195	9.7
Lung	HCC15	9.6
Lung	HCC2279	9.9
Lung	HCC2935	9.5
Lung	HCC33	8.9
Lung	HCC366	8.1
Lung	HCC4006	9.6
Lung	HCC44	8.3
Lung	HCC78	8.7
Lung	HCC827	10.2
Lung	HCC95	9.1
Lung	HLC1	8.8
Lung	HLFA	8.9
Lung	HS229T	9.1
Lung	HS618T	9
Lung	IALM	10.2
Lung	KNS62	8.6
Lung	LC1F	8.5
Lung	LC1SQSF	8.6
Lung	LCLC103H	9.2
Lung	LCLC97TM1	10.2
Lung	LK2	8.8
Lung	LOUNH91	7.2
Lung	LU65	8.6
Lung	LU99	9.6
Lung	LUDLU1	8.5
Lung	LXF289	9
Lung	MORCPR	9.8
Lung	NCIH1048	9.5
Lung	NCIH1092	9
Lung	NCIH1105	9.6
Lung	NCIH1155	8.5
Lung	NCIH1184	10.1
Lung	NCIH1299	9.4
Lung	NCIH1339	9.2
Lung	NCIH1341	8.8
Lung	NCIH1355	9.1
Lung	NCIH1373	9.8
Lung	NCIH1385	7.8
Lung	NCIH1395	8.5
Lung	NCIH1435	8.3
Lung	NCIH1436	8.3
Lung	NCIH1437	7.8
Lung	NCIH146	9.2
Lung	NCIH1563	8.7
Lung	NCIH1568	8.3
Lung	NCIH1573	8.3
Lung	NCIH1581	8.9
Lung	NCIH1618	8.6
Lung	NCIH1623	9.7
Lung	NCIH1648	9.4
Lung	NCIH1650	9.6
Lung	NCIH1651	8.8
Lung	NCIH1666	8.2
Lung	NCIH1693	9.2
Lung	NCIH1694	9
Lung	NCIH1703	9.9
Lung	NCIH1734	9.8
Lung	NCIH1755	8.3
Lung	NCIH1781	8.9
Lung	NCIH1792	8.7
Lung	NCIH1793	9.6
Lung	NCIH1836	8.8
Lung	NCIH1838	9
Lung	NCIH1869	9.7
Lung	NCIH1876	9.9
Lung	NCIH1915	8.6
Lung	NCIH1930	8.8
Lung	NCIH1944	7.5
Lung	NCIH1963	9.3
Lung	NCIH196	8.7
Lung	NCIH1975	10.5
Lung	NCIH2009	8.2
Lung	NCIH2023	8.6
Lung	NCIH2029	10.4
Lung	NCIH2030	9.4
Lung	NCIH2066	9.7
Lung	NCIH2081	9.9
Lung	NCIH2085	9
Lung	NCIH2087	9.1
Lung	NCIH209	9.5
Lung	NCIH2106	10
Lung	NCIH2110	8.8
Lung	NCIH211	11
Lung	NCIH2122	8.5
Lung	NCIH2126	7.9
Lung	NCIH2141	8.9
Lung	NCIH2170	8.6
Lung	NCIH2171	9.1
Lung	NCIH2172	7.9
Lung	NCIH2196	8.5
Lung	NCIH2227	9.6
Lung	NCIH2228	9.5
Lung	NCIH226	9.4
Lung	NCIH2286	9.4
Lung	NCIH2291	10.1
Lung	NCIH2342	8.6
Lung	NCIH2347	10.2
Lung	NCIH23	9.6
Lung	NCIH2405	9.3
Lung	NCIH2444	9.6
Lung	NCIH292	8.9
Lung	NCIH322	10.4
Lung	NCIH3255	9.4
Lung	NCIH358	8.8
Lung	NCIH441	10.2
Lung	NCIH446	9.8
Lung	NCIH460	8.4
Lung	NCIH510	9.5
Lung	NCIH520	9.4
Lung	NCIH522	9.8
Lung	NCIH524	9.8
Lung	NCIH526	9.5
Lung	NCIH596	9.5
Lung	NCIH647	9
Lung	NCIH650	9.8
Lung	NCIH661	9.6
Lung	NCIH69	9.4
Lung	NCIH727	10.1
Lung	NCIH810	9.1
Lung	NCIH82	9.4
Lung	NCIH838	8.2
Lung	NCIH841	10.2
Lung	NCIH854	8
Lung	NCIH889	9.5
Lung	PC14	9.1
Lung	RERFLCAD1	10.1
Lung	RERFLCAD2	8.8
Lung	RERFLCAI	9.1
Lung	RERFLCKJ	8.6
Lung	RERFLCMS	8.7
Lung	RERFLCSQ1	9.2
Lung	SBC5	8.9
Lung	SCLC21H	8.9
Lung	SHP77	8.2
Lung	SKLU1	10.6
Lung	SKMES1	9.3
Lung	SQ1	9.1
Lung	SW1271	10.4
Lung	SW1573	9.1
Lung	SW900	9.4
Lung	VMRCLCD	8.6
Lung	VMRCLCP	10.2
Oesophagus	COLO680N	9.1
Oesophagus	ECGI10	9.3
Oesophagus	KYSE140	9.5
Oesophagus	KYSE150	10.5
Oesophagus	KYSE180	10
Oesophagus	KYSE270	8.6
Oesophagus	KYSE30	9.2
Oesophagus	KYSE410	9.3
Oesophagus	KYSE450	8.4
Oesophagus	KYSE510	9.5
Oesophagus	KYSE520	9.1
Oesophagus	KYSE70	8.8
Oesophagus	OE19	8.5
Oesophagus	OE33	8.5
Oesophagus	TE10	10.2
Oesophagus	TE11	9.4
Oesophagus	TE14	10
Oesophagus	TE15	9.4
Oesophagus	TE1	10.4
Oesophagus	TE4	9.2
Oesophagus	TE5	9.4
Oesophagus	TE6	8.7
Oesophagus	TE8	9.8
Oesophagus	TE9	9.9
Oesophagus	TT	9.5
Ovary	59M	8.8
Ovary	A2780	9.7
Ovary	CAOV3	9.2
Ovary	CAOV4	8.8
Ovary	COLO704	9.7
Ovary	COV318	9.9
Ovary	COV362	9.3
Ovary	COV434	8.5
Ovary	COV504	9.1
Ovary	COV644	8.8
Ovary	EFO21	7.3
Ovary	EFO27	10.1
Ovary	ES2	8.9
Ovary	FUOV1	9.3
Ovary	HEYA8	9.3
Ovary	HS571T	9.3
Ovary	IGROV1	9.5
Ovary	JHOC5	8.5
Ovary	JHOM1	9.4
Ovary	JHOM2B	8.4
Ovary	JHOS2	9.2
Ovary	JHOS4	9.4
Ovary	KURAMOCHI	9.2
Ovary	MCAS	8.8
Ovary	NIHOVCAR3	8.9
Ovary	OAW28	9.2
Ovary	OAW42	8.7
Ovary	OC314	8.9
Ovary	OC316	9.3
Ovary	ONCODG1	8.3
Ovary	OV56	9.7
Ovary	OV7	8.6
Ovary	OV90	7.9
Ovary	OVCAR4	8.6
Ovary	OVCAR8	9.6
Ovary	OVISE	8.7
Ovary	OVK18	9.7
Ovary	OVKATE	9
Ovary	OVMANA	8.8
Ovary	OVSAHO	9
Ovary	OVTOKO	8.3
Ovary	RMGI	8.3
Ovary	RMUGS	9.6
Ovary	SKOV3	7.2
Ovary	SNU119	9.3
Ovary	SNU840	9.1
Ovary	SNU8	9.6
Ovary	TOV112D	9.6
Ovary	TOV21G	8.7
Ovary	TYKNU	9.1
Pancreas	ASPC1	8.9
Pancreas	BXPC3	9.3
Pancreas	CAPAN1	8.9
Pancreas	CAPAN2	9.7
Pancreas	CFPAC1	8.4
Pancreas	DANG	9.2
Pancreas	HPAC	9
Pancreas	HPAFII	9.7
Pancreas	HS766T	9.2
Pancreas	HUPT3	9.3
Pancreas	HUPT4	9.3
Pancreas	KCIMOH1	8.3
Pancreas	KLM1	9
Pancreas	KP2	9.3
Pancreas	KP3	9.5
Pancreas	KP4	10.1
Pancreas	L33	9.7
Pancreas	MIAPACA2	9.9
Pancreas	PANC0203	10.1
Pancreas	PANC0213	9.1
Pancreas	PANC0327	10.2
Pancreas	PANC0403	8.3
Pancreas	PANC0504	9.5
Pancreas	PANC0813	9.3
Pancreas	PANC1005	9.9
Pancreas	PANC1	8.4
Pancreas	PATU8902	10.5
Pancreas	PATU8988S	9
Pancreas	PATU8988T	8.8
Pancreas	PK1	8.8
Pancreas	PK45H	9.8
Pancreas	PK59	8.9
Pancreas	PL45	9.7
Pancreas	PSN1	9.4
Pancreas	QGP1	8.8
Pancreas	SNU213	9.7
Pancreas	SNU324	9
Pancreas	SNU410	10.1
Pancreas	SU8686	8.6
Pancreas	SUIT2	7.9
Pancreas	SW1990	8.4
Pancreas	T3M4	8.8
Pancreas	TCCPAN2	8.9
Pancreas	YAPC	9.3
Pleura	ACCMESO1	9.2
Pleura	DM3	9
Pleura	ISTMES1	8.7
Pleura	ISTMES2	9.8
Pleura	JL1	10.2
Pleura	MPP89	8.1
Pleura	MSTO211H	9.6
Pleura	NCIH2052	9.1
Pleura	NCIH2452	9.9
Pleura	NCIH28	8.6
Prostate	22RV1	7.7
Prostate	DU145	8.5
Prostate	LNCAPCLONEFGC	8.4
Prostate	MDAPCA2B	9
Prostate	NCIH660	9.1
Prostate	PC3	8.3
Prostate	VCAP	9.5
Salivary gland	A253	9.7
Salivary gland	YD15	10
Skin	A101D	9.1
Skin	A2058	8.1
Skin	A375	9.3
Skin	C32	9.4
Skin	CHL1	8.9
Skin	CJM	8.9
Skin	COLO679	8.2
Skin	COLO741	8.7
Skin	COLO783	9.4
Skin	COLO792	7.6
Skin	COLO800	8.3
Skin	COLO818	9
Skin	COLO829	9.9
Skin	COLO849	9.3
Skin	G361	8.7
Skin	GRM	8.4
Skin	HMCB	9
Skin	HS294T	8.7
Skin	HS600T	8.9
Skin	HS688AT	9.2
Skin	HS695T	9.3
Skin	HS839T	8.9
Skin	HS852T	9.3
Skin	HS895T	8.2
Skin	HS934T	9
Skin	HS936T	8.4
Skin	HS939T	9.1
Skin	HS940T	9.1
Skin	HS944T	9.4
Skin	HT144	9.2
Skin	IGR1	8.8
Skin	IGR37	9.1
Skin	IGR39	9.8
Skin	IPC298	9.4
Skin	K029AX	9.6
Skin	LOXIMVI	9.4
Skin	MALME3M	8.5
Skin	MDAMB435S	8.9
Skin	MELHO	8
Skin	MELJUSO	8.8
Skin	MEWO	9.5
Skin	RPMI7951	10
Skin	RVH421	9.6
Skin	SH4	8.6
Skin	SKMEL1	9.3
Skin	SKMEL24	9.5
Skin	SKMEL28	9.1
Skin	SKMEL2	8.9
Skin	SKMEL30	8.9
Skin	SKMEL31	9.3
Skin	SKMEL3	9.2
Skin	SKMEL5	8.6
Skin	UACC257	9
Skin	UACC62	10.1
Skin	WM115	9.9
Skin	WM1799	8.3
Skin	WM2664	8.2
Skin	WM793	8.4
Skin	WM88	8.6
Skin	WM983B	8.7
Small intestine	HUTU80	9.4
Soft tissue	A204	8.7
Soft tissue	G401	9.5
Soft tissue	G402	9.6
Soft tissue	GCT	9.8
Soft tissue	HS729	9.2
Soft tissue	HT1080	8.8
Soft tissue	KYM1	9.2
Soft tissue	MESSA	9.6
Soft tissue	RD	9.9
Soft tissue	RH30	9.4
Soft tissue	RH41	9.4
Soft tissue	RKN	9.2
Soft tissue	S117	9.2
Soft tissue	SJRH30	9.6
Soft tissue	SKLMS1	9.4
Soft tissue	SKUT1	10.1
Soft tissue	TE125T	8.3
Soft tissue	TE159T	8.5
Soft tissue	TE441T	9.5
Soft tissue	TE617T	9.5
Stomach	2313287	8.4
Stomach	AGS	9.2
Stomach	AZ521	8.8
Stomach	ECC10	9.6
Stomach	ECC12	10.4
Stomach	FU97	9.1
Stomach	GCIY	10
Stomach	GSS	8.9
Stomach	GSU	9
Stomach	HGC27	10.1
Stomach	HS746T	10.6
Stomach	HUG1N	9
Stomach	IM95	9
Stomach	KATOIII	9.4
Stomach	KE39	9.7
Stomach	LMSU	8.4
Stomach	MKN1	9.9
Stomach	MKN45	9.8
Stomach	MKN74	9.8
Stomach	MKN7	9.3
Stomach	NCCSTCK140	8.9
Stomach	NCIN87	9.6
Stomach	NUGC2	10.1
Stomach	NUGC3	9
Stomach	NUGC4	10.1
Stomach	OCUM1	8.7
Stomach	RERFGC1B	9.7
Stomach	SH10TC	10.2
Stomach	SNU16	8.6
Stomach	SNU1	8.6
Stomach	SNU216	9.4
Stomach	SNU520	9.4
Stomach	SNU5	9.5
Stomach	SNU601	8.4
Stomach	SNU620	9.2
Stomach	SNU668	8.3
Stomach	SNU719	7.9
Stomach	TGBC11TKB	9.5
Thyroid	8305C	9.3
Thyroid	8505C	9.5
Thyroid	BCPAP	9.7
Thyroid	BHT101	9.1
Thyroid	CAL62	9.9
Thyroid	CGTHW1	9.1
Thyroid	FTC133	8.7
Thyroid	FTC238	7.5
Thyroid	ML1	8.8
Thyroid	SW579	9
Thyroid	TT2609C02	9.5
Thyroid	TT	9.4
Upper aerodigestive tract	BHY	10.3
Upper aerodigestive tract	BICR16	9.4
Upper aerodigestive tract	BICR18	9.9
Upper aerodigestive tract	BICR22	9.6
Upper aerodigestive tract	BICR31	8.4
Upper aerodigestive tract	BICR56	9.5
Upper aerodigestive tract	BICR6	9.3
Upper aerodigestive tract	CAL27	10.2
Upper aerodigestive tract	CAL33	8.3
Upper aerodigestive tract	DETROIT562	9
Upper aerodigestive tract	FADU	9
Upper aerodigestive tract	HS840T	9.1
Upper aerodigestive tract	HSC2	10.4
Upper aerodigestive tract	HSC3	9.7
Upper aerodigestive tract	HSC4	9.7
Upper aerodigestive tract	PECAPJ15	8.8
Upper aerodigestive tract	PECAPJ34CLONEC12	9.4
Upper aerodigestive tract	PECAPJ41CLONED2	10.1
Upper aerodigestive tract	PECAPJ49	9.5
Upper aerodigestive tract	SCC15	9.8
Upper aerodigestive tract	SCC25	9.6
Upper aerodigestive tract	SCC4	9.3
Upper aerodigestive tract	SCC9	8.8
Upper aerodigestive tract	SNU1076	10.9
Upper aerodigestive tract	SNU1214	9.8
Upper aerodigestive tract	SNU46	9.9
Upper aerodigestive tract	SNU899	8.8
Upper aerodigestive tract	YD10B	9.8
Upper aerodigestive tract	YD38	9
Upper aerodigestive tract	YD8	10
Urinary tract	5637	9.5
Urinary tract	639V	9.7
Urinary tract	647V	9.6
Urinary tract	BC3C	9.5
Urinary tract	BFTC905	9.7
Urinary tract	CAL29	9.4
Urinary tract	HS172T	8.3
Urinary tract	HT1197	9.5
Urinary tract	HT1376	9
Urinary tract	J82	9.8
Urinary tract	JMSU1	9.2
Urinary tract	KMBC2	10.2
Urinary tract	KU1919	9.3
Urinary tract	RT11284	8.9
Urinary tract	RT112	8.4
Urinary tract	RT4	9.5
Urinary tract	SCABER	9.5
Urinary tract	SW1710	8.1
Urinary tract	SW780	9.1
Urinary tract	T24	9.6
Urinary tract	TCCSUP	8.3
Urinary tract	UMUC1	8.3
Urinary tract	UMUC3	9.4
Urinary tract	VMCUB1	9

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	14.4
Adrenal gland	14.2
Appendix	23.3
Bone marrow	20.8
Breast	18.3
Cerebral cortex	22
Cervix, uterine	20.8
Colon	11.6
Duodenum	8.5
Endometrium	26.6
Epididymis	17.6
Esophagus	15.9
Fallopian tube	22.2
Gallbladder	19.6
Heart muscle	11.1
Kidney	12
Liver	7.5
Lung	20.3
Lymph node	33.1
Ovary	22.1
Pancreas	2.3
Parathyroid gland	39
Placenta	20.7
Prostate	21.1
Rectum	15.5
Salivary gland	11.9
Seminal vesicle	16.6
Skeletal muscle	5.7
Skin	20.4
Small intestine	11
Smooth muscle	24.7
Spleen	29.3
Stomach	13.4
Testis	61.7
Thyroid gland	37.6
Tonsil	26.9
Urinary bladder	20.5

> Text Mining based Expression [ TOP ]
There is no record.

Summary
Symbol	ATF7IP
Name	activating transcription factor 7 interacting protein
Aliases	FLJ10688; p621; ATF-IP; MCAF1; ATF-interacting protein; ATF7-interacting protein; ATFa-associated modulator; ......
Location	12p13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.297	1.21e-09	16.3	54.5	29.2	Neutral
BRCA	Breast invasive carcinoma	1075	0.227	4.75e-14	17	61.9	21.1	Neutral
CESC	Cervical and endocervical cancers	292	0.146	0.0126	16.4	66.1	17.5	Neutral
COAD	Colon adenocarcinoma	449	0.173	0.000234	12.7	65.9	21.4	Neutral
ESCA	Esophageal carcinoma	183	0.338	2.83e-06	18.6	47.5	33.9	Gain
GBM	Glioblastoma multiforme	147	-0.03	0.719	10.2	79.6	10.2	Neutral
HNSC	Head and Neck squamous cell carcinoma	514	0.215	9.05e-07	8.9	61.1	30	Neutral
KIRC	Kidney renal clear cell carcinoma	525	0.097	0.0257	1.1	76	22.9	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	-0.016	0.783	0.7	60.1	39.2	Gain
LAML	Acute Myeloid Leukemia	166	0	0.998	4.8	95.2	0	Neutral
LGG	Brain Lower Grade Glioma	513	0.113	0.0104	6.2	85.4	8.4	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.23	9.51e-06	22.5	66.8	10.7	Neutral
LUAD	Lung adenocarcinoma	512	0.302	3.19e-12	27.7	46.5	25.8	Neutral
LUSC	Lung squamous cell carcinoma	498	0.219	7.67e-07	7.6	44	48.4	Gain
OV	Ovarian serous cystadenocarcinoma	300	0.388	3.08e-12	16	34.3	49.7	Gain
PAAD	Pancreatic adenocarcinoma	177	0.169	0.0244	14.7	68.4	16.9	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	0.083	0.295	1.9	91.4	6.8	Neutral
PRAD	Prostate adenocarcinoma	491	0.108	0.0165	20.4	76.4	3.3	Neutral
READ	Rectum adenocarcinoma	164	0.22	0.00457	18.3	61.6	20.1	Neutral
SARC	Sarcoma	255	0.228	0.000249	29.8	51	19.2	Neutral
SKCM	Skin Cutaneous Melanoma	367	0.169	0.00114	15.5	66.2	18.3	Neutral
STAD	Stomach adenocarcinoma	413	0.231	1.99e-06	17.7	60.5	21.8	Neutral
TGCT	Testicular Germ Cell Tumors	150	0.295	0.000249	0	2	98	Gain
THCA	Thyroid carcinoma	497	-0.076	0.0891	0.2	97.2	2.6	Neutral
THYM	Thymoma	119	-0.088	0.341	5.9	89.9	4.2	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.155	0.000311	8.2	77.1	14.7	Neutral

Summary
Symbol	ATF7IP
Name	activating transcription factor 7 interacting protein
Aliases	FLJ10688; p621; ATF-IP; MCAF1; ATF-interacting protein; ATF7-interacting protein; ATFa-associated modulator; ......
Location	12p13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

[ TOP ]

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.222	4.09e-06	17	408	0.008	0.106	NS/NA
BRCA	Breast invasive carcinoma	-0.222	4.37e-11	83	785	0.002	0.00733	NS/NA
CESC	Cervical and endocervical cancers	-0.246	1.25e-05	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.153	0.0065	19	297	-0.12	1.68e-09	NS/NA
ESCA	Esophageal carcinoma	-0.235	0.000977	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.206	0.099	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.356	8.1e-18	20	522	0.003	0.00198	NS/NA
KIRC	Kidney renal clear cell carcinoma	-0.184	0.000615	24	319	0.043	0.201	NS/NA
KIRP	Kidney renal papillary cell carcinoma	-0.409	2.05e-13	23	275	0.018	2.55e-08	NS/NA
LAML	Acute Myeloid Leukemia	-0.319	2.5e-05	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	-0.286	2.55e-11	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.27	2.71e-08	41	373	0.029	1.84e-36	NS/NA
LUAD	Lung adenocarcinoma	-0.146	0.00141	21	456	-0.141	3.27e-20	NS/NA
LUSC	Lung squamous cell carcinoma	-0.168	0.00106	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	-0.617	0.0857	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.352	1.21e-06	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.129	0.0776	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.415	0	35	498	0.029	2.42e-38	NS/NA
READ	Rectum adenocarcinoma	-0.344	0.000457	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.324	9.52e-08	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.338	6.32e-14	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.223	1.49e-05	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.305	0.000119	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.11	0.00933	50	509	0.003	0.886	NS/NA
THYM	Thymoma	-0.11	0.227	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.133	0.004	34	431	-0.002	0.00261	NS/NA

Summary
Symbol	ATF7IP
Name	activating transcription factor 7 interacting protein
Aliases	FLJ10688; p621; ATF-IP; MCAF1; ATF-interacting protein; ATF7-interacting protein; ATFa-associated modulator; ......
Location	12p13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Level	Level Name
Adrenal gland	2	Medium
Appendix	2	Medium
Bone marrow	1	Low
Breast	2	Medium
Bronchus	1	Low
Caudate	2	Medium
Cerebellum	2	Medium
Cerebral cortex	2	Medium
Cervix, uterine	3	High
Colon	2	Medium
Duodenum	2	Medium
Endometrium	2	Medium
Epididymis	2	Medium
Esophagus	3	High
Fallopian tube	3	High
Gallbladder	2	Medium
Heart muscle	1	Low
Hippocampus	1	Low
Kidney	2	Medium
Liver	0	Not detected
Lung	1	Low
Lymph node	2	Medium
Oral mucosa	3	High
Ovary	1	Low
Pancreas	2	Medium
Parathyroid gland	2	Medium
Placenta	2	Medium
Prostate	1	Low
Rectum	2	Medium
Salivary gland	3	High
Seminal vesicle	2	Medium
Skeletal muscle	0	Not detected
Skin	3	High
Small intestine	3	High
Smooth muscle	0	Not detected
Soft tissue	1	Low
Spleen	2	Medium
Stomach	2	Medium
Testis	2	Medium
Thyroid gland	2	Medium
Tonsil	3	High
Urinary bladder	2	Medium
Vagina	3	High

Summary
Symbol	ATF7IP
Name	activating transcription factor 7 interacting protein
Aliases	FLJ10688; p621; ATF-IP; MCAF1; ATF-interacting protein; ATF7-interacting protein; ATFa-associated modulator; ......
Location	12p13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.914	NS	24476821
BRCA	Breast invasive carcinoma	521	1.71e-06	Significant	23000897
COAD	Colon adenocarcinoma	149	0.0126	Significant	22810696
GBM	Glioblastoma multiforme	157	1.24e-05	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	0.359	NS	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.00234	Significant	26536169
LGG	Brain Lower Grade Glioma	513	7.78e-09	Significant	26824661
LUAD	Lung adenocarcinoma	230	0.342	NS	25079552
LUSC	Lung squamous cell carcinoma	178	0.551	NS	22960745
OV	Ovarian serous cystadenocarcinoma	287	0.00888	Significant	21720365
PRAD	Prostate adenocarcinoma	333	0.0537	NS	26544944
READ	Rectum adenocarcinoma	67	0.928	NS	22810696
SKCM	Skin Cutaneous Melanoma	315	0.366	NS	26091043
STAD	Stomach adenocarcinoma	277	0.00196	Significant	25079317
THCA	Thyroid carcinoma	391	0.000138	Significant	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	8.12e-06	Significant	23636398

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	1.024	0.91	NS
BRCA	Breast invasive carcinoma	1079	1.384	0.17	NS
CESC	Cervical and endocervical cancers	291	1.045	0.899	NS
COAD	Colon adenocarcinoma	439	0.987	0.964	NS
ESCA	Esophageal carcinoma	184	0.986	0.966	NS
GBM	Glioblastoma multiforme	158	0.539	0.0167	Longer
HNSC	Head and Neck squamous cell carcinoma	518	0.815	0.298	NS
KIRC	Kidney renal clear cell carcinoma	531	0.57	0.00892	Longer
KIRP	Kidney renal papillary cell carcinoma	287	1.651	0.248	NS
LAML	Acute Myeloid Leukemia	149	1.054	0.847	NS
LGG	Brain Lower Grade Glioma	511	0.691	0.166	NS
LIHC	Liver hepatocellular carcinoma	365	0.875	0.582	NS
LUAD	Lung adenocarcinoma	502	0.88	0.555	NS
LUSC	Lung squamous cell carcinoma	494	0.888	0.561	NS
OV	Ovarian serous cystadenocarcinoma	303	0.927	0.727	NS
PAAD	Pancreatic adenocarcinoma	177	1.716	0.067	NS
PCPG	Pheochromocytoma and Paraganglioma	179	681050285.676	0.0332	Shorter
PRAD	Prostate adenocarcinoma	497	0.974	0.985	NS
READ	Rectum adenocarcinoma	159	0.854	0.777	NS
SARC	Sarcoma	259	1.034	0.913	NS
SKCM	Skin Cutaneous Melanoma	459	1.254	0.233	NS
STAD	Stomach adenocarcinoma	388	1.108	0.661	NS
TGCT	Testicular Germ Cell Tumors	134	2.826	0.347	NS
THCA	Thyroid carcinoma	500	0.928	0.927	NS
THYM	Thymoma	119	0.788	0.814	NS
UCEC	Uterine Corpus Endometrial Carcinoma	543	1.746	0.0582	NS

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	0.013	0.8	NS
BRCA	Breast invasive carcinoma	1071	-0.013	0.667	NS
CESC	Cervical and endocervical cancers	167	0.016	0.833	NS
COAD	Colon adenocarcinoma	445	-0.031	0.51	NS
ESCA	Esophageal carcinoma	162	0.006	0.941	NS
HNSC	Head and Neck squamous cell carcinoma	448	-0.087	0.0669	NS
KIRC	Kidney renal clear cell carcinoma	531	-0.07	0.109	NS
KIRP	Kidney renal papillary cell carcinoma	260	0.105	0.092	NS
LIHC	Liver hepatocellular carcinoma	347	0.042	0.438	NS
LUAD	Lung adenocarcinoma	507	0.053	0.229	NS
LUSC	Lung squamous cell carcinoma	497	0.026	0.569	NS
OV	Ovarian serous cystadenocarcinoma	302	-0.038	0.513	NS
PAAD	Pancreatic adenocarcinoma	176	0.094	0.215	NS
READ	Rectum adenocarcinoma	156	-0.128	0.112	NS
SKCM	Skin Cutaneous Melanoma	410	-0.045	0.361	NS
STAD	Stomach adenocarcinoma	392	0.136	0.00708	Higher
TGCT	Testicular Germ Cell Tumors	81	0.102	0.366	NS
THCA	Thyroid carcinoma	499	-0.059	0.185	NS
UCEC	Uterine Corpus Endometrial Carcinoma	501	0.05	0.261	NS

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	-0.038	0.53	NS
HNSC	Head and Neck squamous cell carcinoma	498	-0.104	0.02	Lower
KIRC	Kidney renal clear cell carcinoma	525	-0.024	0.579	NS
LGG	Brain Lower Grade Glioma	514	0.051	0.249	NS
LIHC	Liver hepatocellular carcinoma	366	0.002	0.975	NS
OV	Ovarian serous cystadenocarcinoma	296	0.101	0.083	NS
PAAD	Pancreatic adenocarcinoma	176	0.107	0.158	NS
STAD	Stomach adenocarcinoma	406	0.094	0.0589	NS
UCEC	Uterine Corpus Endometrial Carcinoma	534	0.19	9.96e-06	Higher

Summary
Symbol	ATF7IP
Name	activating transcription factor 7 interacting protein
Aliases	FLJ10688; p621; ATF-IP; MCAF1; ATF-interacting protein; ATF7-interacting protein; ATFa-associated modulator; ......
Location	12p13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	ATF7IP
Name	activating transcription factor 7 interacting protein
Aliases	FLJ10688; p621; ATF-IP; MCAF1; ATF-interacting protein; ATF7-interacting protein; ATFa-associated modulator; ......
Location	12p13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for ATF7IP.

Summary
Symbol	ATF7IP
Name	activating transcription factor 7 interacting protein
Aliases	FLJ10688; p621; ATF-IP; MCAF1; ATF-interacting protein; ATF7-interacting protein; ATFa-associated modulator; ......
Location	12p13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining [ TOP ]
There is no record for ATF7IP.