CR2Cancer

Summary
Symbol	BAZ2A
Name	bromodomain adjacent to zinc finger domain 2A
Aliases	KIAA0314; TIP5; WALp3; TTF-I interacting peptide 5; TTF-I-interacting protein 5; transcription termination f ......
Location	12q13.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

[ TOP ]

Domain

PF00439 Bromodomain
PF02791 DDT domain
PF01429 Methyl-CpG binding domain
PF00628 PHD-finger
PF15612 WSTF
PF15613 Williams-Beuren syndrome DDT (WSD)

Function

Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing. In the complex, it plays a central role by being recruited to rDNA and by targeting chromatin modifying enzymes such as HDAC1, leading to repress RNA polymerase I transcription. Recruited to rDNA via its interaction with TTF1 and its ability to recognize and bind histone H4 acetylated on 'Lys-16' (H4K16ac), leading to deacetylation of H4K5ac, H4K8ac, H4K12ac but not H4K16ac. Specifically binds pRNAs, 150-250 nucleotide RNAs that are complementary in sequence to the rDNA promoter; pRNA-binding is required for heterochromatin formation and rDNA silencing (By similarity).

Classification

Class	Modification	Substrate	Product	PubMed
Chromatin remodelling, Histone modification erase	#, Histone deacetylation	H4K16ac, DNA motif	H4K5, H4K8, H4K12	11532953

> Gene Ontology [ TOP ]
Biological Process	GO:0000183 chromatin silencing at rDNA GO:0006304 DNA modification GO:0006305 DNA alkylation GO:0006306 DNA methylation GO:0006338 chromatin remodeling GO:0006342 chromatin silencing GO:0006476 protein deacetylation GO:0016458 gene silencing GO:0016570 histone modification GO:0016575 histone deacetylation GO:0032259 methylation GO:0035601 protein deacylation GO:0040029 regulation of gene expression, epigenetic GO:0043414 macromolecule methylation GO:0044728 DNA methylation or demethylation GO:0045814 negative regulation of gene expression, epigenetic GO:0098732 macromolecule deacylation
Molecular Function	GO:0001013 RNA polymerase I regulatory region DNA binding GO:0001046 core promoter sequence-specific DNA binding GO:0001047 core promoter binding GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding GO:0001164 RNA polymerase I CORE element sequence-specific DNA binding GO:0016922 ligand-dependent nuclear receptor binding GO:0042393 histone binding GO:0070577 lysine-acetylated histone binding
Cellular Component	GO:0000785 chromatin GO:0000792 heterochromatin GO:0005677 chromatin silencing complex GO:0017053 transcriptional repressor complex GO:0033553 rDNA heterochromatin GO:0090568 nuclear transcriptional repressor complex

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	R-HSA-212165: Epigenetic regulation of gene expression R-HSA-74160: Gene Expression R-HSA-5250941: Negative epigenetic regulation of rRNA expression R-HSA-427413: NoRC negatively regulates rRNA expression

Summary
Symbol	BAZ2A
Name	bromodomain adjacent to zinc finger domain 2A
Aliases	KIAA0314; TIP5; WALp3; TTF-I interacting peptide 5; TTF-I-interacting protein 5; transcription termination f ......
Location	12q13.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM5788927	c.2309C>T	p.A770V	Substitution - Missense	Breast
COSM941750	c.3125G>A	p.R1042H	Substitution - Missense	Oesophagus
COSM468682	c.755A>G	p.Y252C	Substitution - Missense	Kidney
COSM329171	c.977A>G	p.E326G	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4466821	c.1454C>T	p.P485L	Substitution - Missense	Skin
COSM4949782	c.5161G>T	p.G1721C	Substitution - Missense	Liver
COSM1936479	c.4620G>A	p.W1540*	Substitution - Nonsense	Large_intestine
COSM1180781	c.1726delG	p.E576fs*12	Deletion - Frameshift	Large_intestine
COSM4480739	c.2448C>T	p.I816I	Substitution - coding silent	Skin
COSM431536	c.965T>G	p.L322R	Substitution - Missense	Breast
COSM941724	c.5221C>T	p.R1741C	Substitution - Missense	Large_intestine
COSM3463542	c.1971C>T	p.F657F	Substitution - coding silent	Skin
COSM3812601	c.3995G>T	p.C1332F	Substitution - Missense	Breast
COSM1936583	c.2250G>C	p.K750N	Substitution - Missense	Upper_aerodigestive_tract
COSM1936565	c.2709G>A	p.V903V	Substitution - coding silent	Large_intestine
COSM1184481	c.4475G>T	p.R1492M	Substitution - Missense	Large_intestine
COSM941777	c.1693C>T	p.R565C	Substitution - Missense	Endometrium
COSM5988447	c.3767_3771delCACTG	p.S1256fs*6	Deletion - Frameshift	Salivary_gland
COSM941780	c.1657C>T	p.R553C	Substitution - Missense	Skin
COSM1936693	c.677T>C	p.V226A	Substitution - Missense	Large_intestine
COSM4043661	c.4925T>C	p.L1642P	Substitution - Missense	Stomach
COSM4747307	c.5347delA	p.S1783fs*5	Deletion - Frameshift	Stomach
COSM3676502	c.827T>G	p.L276R	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3463554	c.782C>T	p.S261L	Substitution - Missense	Skin
COSM5940234	c.5686G>A	p.E1896K	Substitution - Missense	Skin
COSM1363125	c.3951T>C	p.P1317P	Substitution - coding silent	Large_intestine
COSM4665216	c.5685G>A	p.A1895A	Substitution - coding silent	Large_intestine
COSM1936607	c.1975G>T	p.E659*	Substitution - Nonsense	Skin
COSM5177792	c.3263G>A	p.R1088H	Substitution - Missense	Large_intestine
COSM4665228	c.4660C>T	p.L1554F	Substitution - Missense	Large_intestine
COSM5626612	c.321C>T	p.L107L	Substitution - coding silent	Oesophagus
COSM5051787	c.2429G>A	p.R810Q	Substitution - Missense	Stomach
COSM459435	c.4834C>T	p.Q1612*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM5721980	c.695C>T	p.T232I	Substitution - Missense	Skin
COSM941786	c.1148G>T	p.S383I	Substitution - Missense	Endometrium
COSM694447	c.4649A>T	p.D1550V	Substitution - Missense	Lung
COSM3463545	c.1378G>A	p.A460T	Substitution - Missense	Skin
COSM4493602	c.4292C>T	p.P1431L	Substitution - Missense	Skin
COSM941731	c.4780G>A	p.D1594N	Substitution - Missense	Endometrium
COSM941788	c.1256G>T	p.S419I	Substitution - Missense	Endometrium
COSM431526	c.5587G>T	p.V1863L	Substitution - Missense	Breast
COSM459430	c.4122C>G	p.F1374L	Substitution - Missense	Cervix
COSM4567241	c.726_727CC>TT	p.Q243*	Substitution - Nonsense	Skin
COSM5904980	c.3211C>T	p.R1071*	Substitution - Nonsense	Skin
COSM4802777	c.3742C>T	p.L1248L	Substitution - coding silent	Liver
COSM1636736	c.1844G>C	p.R615P	Substitution - Missense	Bone
COSM3396084	c.4686G>T	p.Q1562H	Substitution - Missense	Prostate
COSM5580321	c.1043C>T	p.A348V	Substitution - Missense	Skin
COSM1299681	c.3517G>T	p.E1173*	Substitution - Nonsense	Urinary_tract
COSM3463533	c.3107C>T	p.S1036F	Substitution - Missense	Skin
COSM3688350	c.5670C>T	p.F1890F	Substitution - coding silent	Large_intestine
COSM5772992	c.4396C>T	p.P1466S	Substitution - Missense	Breast
COSM4043670	c.4121C>T	p.P1374L	Substitution - Missense	Stomach
COSM1936765	c.27T>C	p.F9F	Substitution - coding silent	Large_intestine
COSM4796743	c.2281G>A	p.G761R	Substitution - Missense	Liver
COSM1184484	c.364C>A	p.P122T	Substitution - Missense	Large_intestine
COSM4934482	c.3153-2A>G	p.?	Unknown	Liver
COSM5721981	c.803C>T	p.T268I	Substitution - Missense	Skin
COSM4842944	c.427C>T	p.R143W	Substitution - Missense	Cervix
COSM941753	c.3062C>T	p.A1021V	Substitution - Missense	Endometrium
COSM3463555	c.509C>T	p.S170F	Substitution - Missense	Skin
COSM3396079	c.4579C>T	p.R1527W	Substitution - Missense	Prostate
COSM5940236	c.5794G>A	p.E1932K	Substitution - Missense	Skin
COSM3772694	c.1444T>C	p.S482P	Substitution - Missense	Pancreas
COSM5012577	c.3834C>A	p.S1278R	Substitution - Missense	Kidney
COSM4488037	c.3373C>T	p.Q1125*	Substitution - Nonsense	Skin
COSM4444426	c.2276G>A	p.R759Q	Substitution - Missense	Large_intestine
COSM1238282	c.4418G>T	p.R1473M	Substitution - Missense	Oesophagus
COSM1196778	c.4328G>A	p.R1443Q	Substitution - Missense	Lung
COSM4606620	c.3862G>A	p.G1288S	Substitution - Missense	Adrenal_gland
COSM4987865	c.5243G>A	p.G1748D	Substitution - Missense	Soft_tissue
COSM3396082	c.4578G>T	p.Q1526H	Substitution - Missense	Prostate
COSM4450207	c.4899-1G>T	p.?	Unknown	Skin
COSM4575597	c.4000G>T	p.A1334S	Substitution - Missense	Bone
COSM5473412	c.1853C>A	p.P618H	Substitution - Missense	Large_intestine
COSM5375652	c.2180G>C	p.R727P	Substitution - Missense	Skin
COSM941768	c.2298A>C	p.E766D	Substitution - Missense	Endometrium
COSM1363138	c.2742C>T	p.S914S	Substitution - coding silent	Large_intestine
COSM4842946	c.535C>T	p.R179W	Substitution - Missense	Cervix
COSM3739785	c.3406T>C	p.F1136L	Substitution - Missense	Liver
COSM4043681	c.1580A>G	p.E527G	Substitution - Missense	Stomach
COSM941749	c.3535T>C	p.L1179L	Substitution - coding silent	Endometrium
COSM1180783	c.1834delG	p.E612fs*12	Deletion - Frameshift	Large_intestine
COSM5042057	c.1204G>A	p.A402T	Substitution - Missense	Liver
COSM941732	c.4373G>A	p.R1458Q	Substitution - Missense	Endometrium
COSM4480741	c.2556C>T	p.I852I	Substitution - coding silent	Skin
COSM5801917	c.1760_1762delAAG	p.E587delE	Deletion - In frame	Breast
COSM3725951	c.312G>A	p.G104G	Substitution - coding silent	Lung
COSM4043685	c.1680C>T	p.D560D	Substitution - coding silent	Stomach
COSM5589792	c.581C>T	p.P194L	Substitution - Missense	Skin
COSM941767	c.2612T>C	p.L871P	Substitution - Missense	Endometrium
COSM5602891	c.1786-1G>A	p.?	Unknown	Skin
COSM3376317	c.4903C>T	p.R1635W	Substitution - Missense	Pancreas
COSM416143	c.4088C>G	p.S1363*	Substitution - Nonsense	Urinary_tract
COSM5983717	c.2910G>A	p.Q970Q	Substitution - coding silent	Upper_aerodigestive_tract
COSM549167	c.5763C>T	p.I1921I	Substitution - coding silent	Bone
COSM5970781	c.1718G>T	p.G573V	Substitution - Missense	Upper_aerodigestive_tract
COSM3463543	c.1270G>A	p.A424T	Substitution - Missense	Skin
COSM3396081	c.4687C>T	p.R1563W	Substitution - Missense	Prostate
COSM4415207	c.52A>G	p.R18G	Substitution - Missense	Large_intestine
COSM1936461	c.4938T>C	p.H1646H	Substitution - coding silent	Large_intestine
COSM329173	c.1085A>G	p.E362G	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5721981	c.803C>T	p.T268I	Substitution - Missense	Skin
COSM1476759	c.3068G>A	p.R1023Q	Substitution - Missense	Breast
COSM6007872	c.5671G>A	p.E1891K	Substitution - Missense	Prostate
COSM941738	c.4242C>A	p.F1414L	Substitution - Missense	Large_intestine
COSM4951349	c.200C>A	p.S67*	Substitution - Nonsense	Liver
COSM4961486	c.2979C>T	p.R993R	Substitution - coding silent	Liver
COSM4043679	c.2312G>T	p.R771I	Substitution - Missense	Stomach
COSM5051789	c.2537G>A	p.R846Q	Substitution - Missense	Stomach
COSM1936618	c.1718G>A	p.W573*	Substitution - Nonsense	Large_intestine
COSM5185654	c.4464C>T	p.I1488I	Substitution - coding silent	Large_intestine
COSM3739781	c.5512A>G	p.M1838V	Substitution - Missense	Liver
COSM4043667	c.4238C>T	p.T1413M	Substitution - Missense	Stomach
COSM1936439	c.5395C>T	p.L1799F	Substitution - Missense	Large_intestine
COSM5576438	c.675C>T	p.S225S	Substitution - coding silent	Skin
COSM318895	c.1702G>A	p.G568R	Substitution - Missense	Lung
COSM5988452	c.3874T>A	p.S1292T	Substitution - Missense	Salivary_gland
COSM468681	c.4490G>T	p.R1497L	Substitution - Missense	Kidney
COSM5038875	c.4093G>T	p.A1365S	Substitution - Missense	Liver
COSM1363122	c.4518_4519insC	p.K1507fs*26	Insertion - Frameshift	Large_intestine
COSM3463557	c.617C>T	p.S206F	Substitution - Missense	Skin
COSM5042821	c.3128G>A	p.S1043N	Substitution - Missense	Liver
COSM1476763	c.967C>A	p.Q323K	Substitution - Missense	Breast
COSM4755912	c.3566G>A	p.R1189Q	Substitution - Missense	Stomach
COSM1936528	c.3133C>T	p.R1045W	Substitution - Missense	Large_intestine
COSM2151288	c.1595C>T	p.S532F	Substitution - Missense	Central_nervous_system
COSM3463527	c.4480C>T	p.R1494*	Substitution - Nonsense	Skin
COSM5106965	c.2072G>A	p.R691H	Substitution - Missense	Large_intestine
COSM549165	c.5655C>T	p.I1885I	Substitution - coding silent	Bone
COSM1195719	c.1175C>T	p.A392V	Substitution - Missense	Lung
COSM941744	c.3694C>A	p.Q1232K	Substitution - Missense	Endometrium
COSM3396081	c.4687C>T	p.R1563W	Substitution - Missense	Prostate
COSM6000766	c.5350C>A	p.P1784T	Substitution - Missense	Prostate
COSM274122	c.3227T>C	p.V1076A	Substitution - Missense	Large_intestine
COSM941785	c.1474G>A	p.A492T	Substitution - Missense	Liver
COSM4043682	c.1688A>G	p.E563G	Substitution - Missense	Stomach
COSM941773	c.1823G>A	p.R608Q	Substitution - Missense	Endometrium
COSM1936446	c.5473C>T	p.R1825*	Substitution - Nonsense	Stomach
COSM4415207	c.52A>G	p.R18G	Substitution - Missense	Large_intestine
COSM5481076	c.2704A>G	p.K902E	Substitution - Missense	Large_intestine
COSM5664030	c.1955G>T	p.R652L	Substitution - Missense	Soft_tissue
COSM941776	c.1814G>A	p.G605D	Substitution - Missense	Endometrium
COSM5721980	c.695C>T	p.T232I	Substitution - Missense	Skin
COSM5105892	c.776_785del10	p.V259fs*14	Deletion - Frameshift	Large_intestine
COSM1299685	c.462C>G	p.T154T	Substitution - coding silent	Urinary_tract
COSM941755	c.3170C>T	p.A1057V	Substitution - Missense	Endometrium
COSM4665224	c.4677C>T	p.S1559S	Substitution - coding silent	Large_intestine
COSM3463546	c.811C>T	p.P271S	Substitution - Missense	Skin
COSM2151288	c.1595C>T	p.S532F	Substitution - Missense	Central_nervous_system
COSM318893	c.1594G>A	p.G532R	Substitution - Missense	Lung
COSM4043672	c.3808C>A	p.L1270M	Substitution - Missense	Stomach
COSM1245995	c.1331C>T	p.A444V	Substitution - Missense	Oesophagus
COSM3463531	c.2999C>T	p.S1000F	Substitution - Missense	Skin
COSM4633701	c.4090G>T	p.A1364S	Substitution - Missense	Large_intestine
COSM3812602	c.4103G>T	p.C1368F	Substitution - Missense	Breast
COSM5721980	c.695C>T	p.T232I	Substitution - Missense	Skin
COSM4917775	c.4925G>T	p.R1642L	Substitution - Missense	Liver
COSM4043651	c.5660G>A	p.R1887H	Substitution - Missense	Stomach
COSM4043669	c.4013C>T	p.P1338L	Substitution - Missense	Stomach
COSM4492737	c.4136C>T	p.S1379F	Substitution - Missense	Skin
COSM4665215	c.5577G>A	p.A1859A	Substitution - coding silent	Large_intestine
COSM4961484	c.2871C>T	p.R957R	Substitution - coding silent	Liver
COSM1195448	c.1600G>A	p.V534I	Substitution - Missense	Lung
COSM5626613	c.429C>T	p.L143L	Substitution - coding silent	Oesophagus
COSM4665221	c.4924C>T	p.R1642C	Substitution - Missense	Large_intestine
COSM127423	c.3009G>A	p.R1003R	Substitution - coding silent	Upper_aerodigestive_tract
COSM1363128	c.3797A>G	p.Q1266R	Substitution - Missense	Large_intestine
COSM5051793	c.307C>A	p.P103T	Substitution - Missense	Stomach
COSM1606397	c.3292A>G	p.I1098V	Substitution - Missense	Liver
COSM4168946	c.4267C>G	p.L1423V	Substitution - Missense	Peritoneum
COSM5051786	c.3117G>A	p.R1039R	Substitution - coding silent	Stomach
COSM3812605	c.486C>A	p.I162I	Substitution - coding silent	Breast
COSM1363132	c.3829_3834delCTTCAG	p.L1277_Q1278delLQ	Deletion - In frame	Large_intestine
COSM4043655	c.5156G>A	p.R1719Q	Substitution - Missense	Stomach
COSM1245997	c.1439C>T	p.A480V	Substitution - Missense	Oesophagus
COSM1195446	c.1492G>A	p.V498I	Substitution - Missense	Lung
COSM1936431	c.5771G>A	p.R1924H	Substitution - Missense	Large_intestine
COSM3676500	c.719T>G	p.L240R	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4934480	c.3045-2A>G	p.?	Unknown	Liver
COSM941782	c.1765C>T	p.R589C	Substitution - Missense	Endometrium
COSM4787724	c.3089A>G	p.K1030R	Substitution - Missense	Liver
COSM5904982	c.3319C>T	p.R1107*	Substitution - Nonsense	Skin
COSM5414355	c.97C>T	p.L33F	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM941724	c.5221C>T	p.R1741C	Substitution - Missense	Endometrium
COSM1628728	c.304A>G	p.N102D	Substitution - Missense	Liver
COSM5051795	c.415C>A	p.P139T	Substitution - Missense	Stomach
COSM5434875	c.1985A>T	p.D662V	Substitution - Missense	Oesophagus
COSM4796745	c.2389G>A	p.G797R	Substitution - Missense	Liver
COSM5124407	c.1025G>A	p.C342Y	Substitution - Missense	Large_intestine
COSM941738	c.4242C>A	p.F1414L	Substitution - Missense	Endometrium
COSM941726	c.5086G>A	p.G1696R	Substitution - Missense	Endometrium
COSM459435	c.4834C>T	p.Q1612*	Substitution - Nonsense	Cervix
COSM1289800	c.5227C>T	p.Q1743*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM4043654	c.5048G>A	p.R1683Q	Substitution - Missense	Stomach
COSM5750037	c.4279C>A	p.P1427T	Substitution - Missense	Stomach
COSM5375640	c.5577C>T	p.N1859N	Substitution - coding silent	Skin
COSM1742844	c.3706A>G	p.M1236V	Substitution - Missense	Biliary_tract
COSM3463561	c.83C>T	p.S28F	Substitution - Missense	Skin
COSM5414356	c.205C>T	p.L69F	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5470057	c.256A>C	p.S86R	Substitution - Missense	Large_intestine
COSM4976412	c.4131A>G	p.A1377A	Substitution - coding silent	Oesophagus
COSM3710799	c.3307G>T	p.G1103C	Substitution - Missense	Upper_aerodigestive_tract
COSM5628755	c.4020_4021insC	p.A1341fs*4	Insertion - Frameshift	Oesophagus
COSM941750	c.3125G>A	p.R1042H	Substitution - Missense	Endometrium
COSM4951351	c.308C>A	p.S103*	Substitution - Nonsense	Liver
COSM941737	c.4395G>A	p.Q1465Q	Substitution - coding silent	Endometrium
COSM3396079	c.4579C>T	p.R1527W	Substitution - Missense	Prostate
COSM459433	c.4726C>T	p.Q1576*	Substitution - Nonsense	Cervix
COSM3700312	c.3760C>T	p.P1254S	Substitution - Missense	Liver
COSM941759	c.2637G>A	p.L879L	Substitution - coding silent	Endometrium
COSM4841242	c.1588A>G	p.K530E	Substitution - Missense	Cervix
COSM3463522	c.4638C>T	p.T1546T	Substitution - coding silent	Skin
COSM3463525	c.4372C>T	p.R1458*	Substitution - Nonsense	Skin
COSM3812595	c.4906G>A	p.E1636K	Substitution - Missense	Breast
COSM4606618	c.3754G>A	p.G1252S	Substitution - Missense	Adrenal_gland
COSM5041912	c.736+1G>A	p.?	Unknown	Liver
COSM1196780	c.4436G>A	p.R1479Q	Substitution - Missense	Lung
COSM1936694	c.785T>C	p.V262A	Substitution - Missense	Large_intestine
COSM3396081	c.4687C>T	p.R1563W	Substitution - Missense	Prostate
COSM3812596	c.5014G>A	p.E1672K	Substitution - Missense	Breast
COSM941752	c.3233G>A	p.R1078H	Substitution - Missense	Endometrium
COSM5820812	c.232A>T	p.S78C	Substitution - Missense	Liver
COSM431527	c.5366G>A	p.R1789Q	Substitution - Missense	Stomach
COSM4043666	c.4130C>T	p.T1377M	Substitution - Missense	Stomach
COSM3396084	c.4686G>T	p.Q1562H	Substitution - Missense	Prostate
COSM4043684	c.1572C>T	p.D524D	Substitution - coding silent	Stomach
COSM4802777	c.3742C>T	p.L1248L	Substitution - coding silent	Liver
COSM3376314	c.5666C>T	p.T1889I	Substitution - Missense	Pancreas
COSM1936440	c.5503C>T	p.L1835F	Substitution - Missense	Large_intestine
COSM5038877	c.4201G>T	p.A1401S	Substitution - Missense	Liver
COSM1363140	c.2313delA	p.V772fs*9	Deletion - Frameshift	Large_intestine
COSM3688352	c.5778C>T	p.F1926F	Substitution - coding silent	Large_intestine
COSM941779	c.1801C>T	p.R601C	Substitution - Missense	Endometrium
COSM5697457	c.1929G>C	p.S643S	Substitution - coding silent	Soft_tissue
COSM1184483	c.4583G>T	p.R1528M	Substitution - Missense	Large_intestine
COSM4043673	c.3916C>A	p.L1306M	Substitution - Missense	Stomach
COSM5051792	c.1037T>C	p.V346A	Substitution - Missense	Stomach
COSM4841240	c.1480A>G	p.K494E	Substitution - Missense	Cervix
COSM4479358	c.2424C>T	p.V808V	Substitution - coding silent	Skin
COSM6000768	c.5458C>A	p.P1820T	Substitution - Missense	Prostate
COSM5721981	c.803C>T	p.T268I	Substitution - Missense	Skin
COSM941752	c.3233G>A	p.R1078H	Substitution - Missense	Oesophagus
COSM1363141	c.2421delA	p.V808fs*9	Deletion - Frameshift	Large_intestine
COSM1289802	c.5335C>T	p.Q1779*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM1196780	c.4436G>A	p.R1479Q	Substitution - Missense	Lung
COSM4894060	c.2757C>T	p.S919S	Substitution - coding silent	Skin
COSM4779910	c.351G>A	p.S117S	Substitution - coding silent	Liver
COSM4043652	c.5768G>A	p.R1923H	Substitution - Missense	Stomach
COSM5574424	c.2317_2318delAA	p.K773fs*23	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM6007874	c.5779G>A	p.E1927K	Substitution - Missense	Prostate
COSM4168946	c.4267C>G	p.L1423V	Substitution - Missense	Liver
COSM279124	c.496G>T	p.E166*	Substitution - Nonsense	Large_intestine
COSM4778807	c.1141+10G>A	p.?	Unknown	Liver
COSM3396084	c.4686G>T	p.Q1562H	Substitution - Missense	Prostate
COSM274120	c.4606C>T	p.R1536W	Substitution - Missense	Large_intestine
COSM431527	c.5366G>A	p.R1789Q	Substitution - Missense	Breast
COSM941785	c.1474G>A	p.A492T	Substitution - Missense	Liver
COSM3463552	c.674C>T	p.S225L	Substitution - Missense	Skin
COSM941725	c.5329C>T	p.R1777C	Substitution - Missense	Endometrium
COSM1628729	c.412A>G	p.N138D	Substitution - Missense	Liver
COSM1184480	c.2263C>T	p.Q755*	Substitution - Nonsense	Large_intestine
COSM3396081	c.4687C>T	p.R1563W	Substitution - Missense	Prostate
COSM5470058	c.364A>C	p.S122R	Substitution - Missense	Large_intestine
COSM3463540	c.1863C>T	p.F621F	Substitution - coding silent	Skin
COSM694436	c.1490C>T	p.P497L	Substitution - Missense	Lung
COSM4755912	c.3566G>A	p.R1189Q	Substitution - Missense	Skin
COSM5964668	c.3262C>T	p.R1088C	Substitution - Missense	Breast
COSM1245994	c.4340C>G	p.P1447R	Substitution - Missense	Oesophagus
COSM1363144	c.464_465insG	p.Q156fs*20	Insertion - Frameshift	Large_intestine
COSM1606396	c.3184A>G	p.I1062V	Substitution - Missense	Liver
COSM3739784	c.3298T>C	p.F1100L	Substitution - Missense	Liver
COSM1363134	c.3119G>A	p.R1040Q	Substitution - Missense	Large_intestine
COSM5803840	c.2189A>G	p.K730R	Substitution - Missense	Liver
COSM5801916	c.1652_1654delAAG	p.E551delE	Deletion - In frame	Breast
COSM941762	c.2518C>T	p.R840*	Substitution - Nonsense	Endometrium
COSM3812599	c.4104C>T	p.C1368C	Substitution - coding silent	Breast
COSM5988450	c.3766T>A	p.S1256T	Substitution - Missense	Salivary_gland
COSM941774	c.1706G>A	p.G569D	Substitution - Missense	Endometrium
COSM3396084	c.4686G>T	p.Q1562H	Substitution - Missense	Prostate
COSM4043675	c.2213G>A	p.R738Q	Substitution - Missense	Stomach
COSM431529	c.5474G>A	p.R1825Q	Substitution - Missense	Stomach
COSM3463534	c.2740C>G	p.P914A	Substitution - Missense	Skin
COSM5566348	c.1694G>A	p.R565H	Substitution - Missense	Prostate
COSM941782	c.1765C>T	p.R589C	Substitution - Missense	Skin
COSM3396082	c.4578G>T	p.Q1526H	Substitution - Missense	Prostate
COSM4043657	c.4898+1G>A	p.?	Unknown	Stomach
COSM4415207	c.52A>G	p.R18G	Substitution - Missense	Large_intestine
COSM1184486	c.472C>A	p.P158T	Substitution - Missense	Large_intestine
COSM4168948	c.4375C>G	p.L1459V	Substitution - Missense	Peritoneum
COSM5715135	c.634T>C	p.F212L	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5803839	c.2081A>G	p.K694R	Substitution - Missense	Liver
COSM5122851	c.2469G>A	p.P823P	Substitution - coding silent	Large_intestine
COSM3396081	c.4687C>T	p.R1563W	Substitution - Missense	Prostate
COSM300460	c.5413A>G	p.I1805V	Substitution - Missense	Large_intestine
COSM1936735	c.350C>T	p.S117L	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5589793	c.689C>T	p.P230L	Substitution - Missense	Skin
COSM3463516	c.5047C>G	p.R1683G	Substitution - Missense	Skin
COSM4949782	c.5161G>T	p.G1721C	Substitution - Missense	Liver
COSM3396082	c.4578G>T	p.Q1526H	Substitution - Missense	Prostate
COSM4755913	c.3674G>A	p.R1225Q	Substitution - Missense	Skin
COSM5750035	c.4171C>A	p.P1391T	Substitution - Missense	Stomach
COSM4796743	c.2281G>A	p.G761R	Substitution - Missense	Liver
COSM694438	c.1598C>T	p.P533L	Substitution - Missense	Lung
COSM941783	c.1366G>A	p.A456T	Substitution - Missense	Endometrium
COSM1299682	c.2703C>T	p.V901V	Substitution - coding silent	Urinary_tract
COSM5771186	c.5640G>C	p.R1880R	Substitution - coding silent	Breast
COSM5788926	c.2201C>T	p.A734V	Substitution - Missense	Breast
COSM3463513	c.5676C>T	p.S1892S	Substitution - coding silent	Skin
COSM1936431	c.5771G>A	p.R1924H	Substitution - Missense	Large_intestine
COSM4488035	c.3265C>T	p.Q1089*	Substitution - Nonsense	Skin
COSM3463549	c.810C>T	p.V270V	Substitution - coding silent	Skin
COSM5983720	c.1915G>A	p.E639K	Substitution - Missense	Upper_aerodigestive_tract
COSM4787722	c.2981A>G	p.K994R	Substitution - Missense	Liver
COSM3987082	c.1147A>T	p.N383Y	Substitution - Missense	Kidney
COSM3700314	c.3868C>T	p.P1290S	Substitution - Missense	Liver
COSM4043676	c.2321G>A	p.R774Q	Substitution - Missense	Stomach
COSM1742843	c.3598A>G	p.M1200V	Substitution - Missense	Biliary_tract
COSM5983719	c.3018G>A	p.Q1006Q	Substitution - coding silent	Upper_aerodigestive_tract
COSM1184481	c.4475G>T	p.R1492M	Substitution - Missense	Large_intestine
COSM431529	c.5474G>A	p.R1825Q	Substitution - Missense	Breast
COSM1936430	c.5663G>A	p.R1888H	Substitution - Missense	Large_intestine
COSM127423	c.3009G>A	p.R1003R	Substitution - coding silent	Stomach
COSM4043690	c.567C>A	p.S189S	Substitution - coding silent	Stomach
COSM4643743	c.5394T>G	p.D1798E	Substitution - Missense	Large_intestine
COSM4802779	c.3850C>T	p.L1284L	Substitution - coding silent	Liver
COSM3463536	c.2848C>G	p.P950A	Substitution - Missense	Skin
COSM941740	c.4350C>A	p.F1450L	Substitution - Missense	Large_intestine
COSM941783	c.1366G>A	p.A456T	Substitution - Missense	Liver
COSM4665227	c.4552C>T	p.L1518F	Substitution - Missense	Large_intestine
COSM3396082	c.4578G>T	p.Q1526H	Substitution - Missense	Prostate
COSM3463537	c.2145G>A	p.K715K	Substitution - coding silent	Skin
COSM4755913	c.3674G>A	p.R1225Q	Substitution - Missense	Stomach
COSM5772990	c.4288C>T	p.P1430S	Substitution - Missense	Breast
COSM3396082	c.4578G>T	p.Q1526H	Substitution - Missense	Prostate
COSM5481075	c.2596A>G	p.K866E	Substitution - Missense	Large_intestine
COSM1363129	c.3905A>G	p.Q1302R	Substitution - Missense	Large_intestine
COSM4951351	c.308C>A	p.S103*	Substitution - Nonsense	Liver
COSM3725950	c.204G>A	p.G68G	Substitution - coding silent	Lung
COSM4747306	c.5239delA	p.S1747fs*5	Deletion - Frameshift	Stomach
COSM941734	c.4481G>A	p.R1494Q	Substitution - Missense	Endometrium
COSM3376312	c.5558C>T	p.T1853I	Substitution - Missense	Pancreas
COSM941758	c.3122A>G	p.N1041S	Substitution - Missense	Endometrium
COSM5473411	c.1745C>A	p.P582H	Substitution - Missense	Large_intestine
COSM1184487	c.5377C>T	p.R1793W	Substitution - Missense	Large_intestine
COSM941785	c.1474G>A	p.A492T	Substitution - Missense	Endometrium
COSM4794196	c.3744G>A	p.Q1248Q	Substitution - coding silent	Liver
COSM5602892	c.1894-1G>A	p.?	Unknown	Skin
COSM4450209	c.5007-1G>T	p.?	Unknown	Skin
COSM4564663	c.1339_1340CC>TT	p.P447L	Substitution - Missense	Skin
COSM4493600	c.4184C>T	p.P1395L	Substitution - Missense	Skin
COSM3463515	c.5784C>T	p.S1928S	Substitution - coding silent	Skin
COSM4415207	c.52A>G	p.R18G	Substitution - Missense	Large_intestine
COSM4910426	c.5246T>C	p.V1749A	Substitution - Missense	Liver
COSM1245992	c.4232C>G	p.P1411R	Substitution - Missense	Oesophagus
COSM4567239	c.618_619CC>TT	p.Q207*	Substitution - Nonsense	Skin
COSM4962836	c.3374A>G	p.Y1125C	Substitution - Missense	Pancreas
COSM5051790	c.929T>C	p.V310A	Substitution - Missense	Stomach
COSM279122	c.4925G>A	p.R1642H	Substitution - Missense	Large_intestine
COSM279120	c.5059A>G	p.N1687D	Substitution - Missense	Large_intestine
COSM459429	c.4024G>T	p.E1342*	Substitution - Nonsense	Cervix
COSM1299687	c.570C>G	p.T190T	Substitution - coding silent	Urinary_tract
COSM4597808	c.3731C>T	p.P1244L	Substitution - Missense	Upper_aerodigestive_tract
COSM4894062	c.2865C>T	p.S955S	Substitution - coding silent	Skin
COSM4794194	c.3636G>A	p.Q1212Q	Substitution - coding silent	Liver
COSM5580322	c.1151C>T	p.A384V	Substitution - Missense	Skin
COSM1476762	c.859C>A	p.Q287K	Substitution - Missense	Breast
COSM5051782	c.3915G>A	p.P1305P	Substitution - coding silent	Stomach
COSM4961484	c.2871C>T	p.R957R	Substitution - coding silent	Liver
COSM1196778	c.4328G>A	p.R1443Q	Substitution - Missense	Lung
COSM1363131	c.3721_3726delCTTCAG	p.L1241_Q1242delLQ	Deletion - In frame	Large_intestine
COSM4492735	c.4028C>T	p.S1343F	Substitution - Missense	Skin
COSM4910424	c.5138T>C	p.V1713A	Substitution - Missense	Liver
COSM4665219	c.5425G>A	p.A1809T	Substitution - Missense	Large_intestine
COSM941764	c.2626C>T	p.R876*	Substitution - Nonsense	Large_intestine
COSM941756	c.3014A>G	p.N1005S	Substitution - Missense	Endometrium
COSM5901772	c.2764C>T	p.L922F	Substitution - Missense	Skin
COSM1184487	c.5377C>T	p.R1793W	Substitution - Missense	Large_intestine
COSM126567	c.1082C>G	p.S361*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM4597806	c.3623C>T	p.P1208L	Substitution - Missense	Upper_aerodigestive_tract
COSM1363135	c.3227G>A	p.R1076Q	Substitution - Missense	Large_intestine
COSM4949780	c.5053G>T	p.G1685C	Substitution - Missense	Liver
COSM86486	c.684A>G	p.A228A	Substitution - coding silent	Ovary
COSM4947184	c.792A>G	p.A264A	Substitution - coding silent	Ovary
COSM3463539	c.2253G>A	p.K751K	Substitution - coding silent	Skin
COSM5375648	c.2724C>T	p.L908L	Substitution - coding silent	Skin
COSM3463548	c.919C>T	p.P307S	Substitution - Missense	Skin
COSM1936739	c.441C>T	p.P147P	Substitution - coding silent	Oesophagus
COSM3396079	c.4579C>T	p.R1527W	Substitution - Missense	Prostate
COSM3396079	c.4579C>T	p.R1527W	Substitution - Missense	Prostate
COSM4665218	c.5317G>A	p.A1773T	Substitution - Missense	Large_intestine
COSM5988449	c.3875_3879delCACTG	p.S1292fs*6	Deletion - Frameshift	Salivary_gland
COSM5584538	c.2958A>G	p.V986V	Substitution - coding silent	Skin
COSM1606397	c.3292A>G	p.I1098V	Substitution - Missense	Liver
COSM5042055	c.1096G>A	p.A366T	Substitution - Missense	Liver
COSM4415207	c.52A>G	p.R18G	Substitution - Missense	Large_intestine
COSM4962838	c.3482A>G	p.Y1161C	Substitution - Missense	Pancreas
COSM3812604	c.378C>A	p.I126I	Substitution - coding silent	Breast
COSM3463546	c.811C>T	p.P271S	Substitution - Missense	Skin
COSM1936431	c.5771G>A	p.R1924H	Substitution - Missense	Large_intestine
COSM5547102	c.1042_1056del15	p.G348_G352delGGLYG	Deletion - In frame	Prostate
COSM3396082	c.4578G>T	p.Q1526H	Substitution - Missense	Prostate
COSM5771184	c.5532G>C	p.R1844R	Substitution - coding silent	Breast
COSM431533	c.3017delA	p.K1006fs*11	Deletion - Frameshift	Breast
COSM5375655	c.215delA	p.N72fs*5	Deletion - Frameshift	Skin
COSM941746	c.3802C>A	p.Q1268K	Substitution - Missense	Endometrium
COSM941765	c.2504T>C	p.L835P	Substitution - Missense	Endometrium
COSM3396084	c.4686G>T	p.Q1562H	Substitution - Missense	Prostate
COSM4427093	c.2287C>G	p.Q763E	Substitution - Missense	Oesophagus
COSM1936766	c.135T>C	p.F45F	Substitution - coding silent	Large_intestine
COSM1660735	c.1552T>G	p.L518V	Substitution - Missense	Kidney
COSM1184489	c.5485C>T	p.R1829W	Substitution - Missense	Large_intestine
COSM1289805	c.2206+1G>A	p.?	Unknown	Haematopoietic_and_lymphoid_tissue
COSM4479356	c.2316C>T	p.V772V	Substitution - coding silent	Skin
COSM3812598	c.3996C>T	p.C1332C	Substitution - coding silent	Breast
COSM3463551	c.918C>T	p.V306V	Substitution - coding silent	Skin
COSM5375646	c.4905G>A	p.R1635R	Substitution - coding silent	Skin
COSM468679	c.4382G>T	p.R1461L	Substitution - Missense	Kidney
COSM4043687	c.1436C>A	p.A479E	Substitution - Missense	Stomach
COSM4444426	c.2276G>A	p.R759Q	Substitution - Missense	Large_intestine
COSM4494072	c.4266C>T	p.Y1422Y	Substitution - coding silent	Skin
COSM5664031	c.2063G>T	p.R688L	Substitution - Missense	Soft_tissue
COSM1238284	c.4526G>T	p.R1509M	Substitution - Missense	Oesophagus
COSM3987079	c.1406C>T	p.T469I	Substitution - Missense	Kidney
COSM5547101	c.934_948del15	p.G312_G316delGGLYG	Deletion - In frame	Prostate
COSM3463524	c.4746C>T	p.T1582T	Substitution - coding silent	Skin
COSM4917777	c.5033G>T	p.R1678L	Substitution - Missense	Liver
COSM3376315	c.4795C>T	p.R1599W	Substitution - Missense	Pancreas
COSM5584537	c.2850A>G	p.V950V	Substitution - coding silent	Skin
COSM5697458	c.2037G>C	p.S679S	Substitution - coding silent	Soft_tissue
COSM3463518	c.5155C>G	p.R1719G	Substitution - Missense	Skin
COSM5375642	c.5379G>A	p.R1793R	Substitution - coding silent	Skin
COSM459427	c.3916G>T	p.E1306*	Substitution - Nonsense	Cervix
COSM4951349	c.200C>A	p.S67*	Substitution - Nonsense	Liver
COSM3463566	c.185C>T	p.S62F	Substitution - Missense	Skin
COSM1636737	c.1952G>C	p.R651P	Substitution - Missense	Bone
COSM4168946	c.4267C>G	p.L1423V	Substitution - Missense	Liver
COSM1660734	c.1444T>G	p.L482V	Substitution - Missense	Kidney
COSM5970779	c.1610G>T	p.G537V	Substitution - Missense	Upper_aerodigestive_tract
COSM5983722	c.2023G>A	p.E675K	Substitution - Missense	Upper_aerodigestive_tract
COSM431524	c.5479G>T	p.V1827L	Substitution - Missense	Breast
COSM3463528	c.3111C>T	p.C1037C	Substitution - coding silent	Skin
COSM1936460	c.4830T>C	p.H1610H	Substitution - coding silent	Large_intestine
COSM5015129	c.2275C>T	p.R759W	Substitution - Missense	Kidney
COSM941764	c.2626C>T	p.R876*	Substitution - Nonsense	Endometrium
COSM4564665	c.1447_1448CC>TT	p.P483L	Substitution - Missense	Skin
COSM1299684	c.2811C>T	p.V937V	Substitution - coding silent	Urinary_tract
COSM5820813	c.340A>T	p.S114C	Substitution - Missense	Liver
COSM1936430	c.5663G>A	p.R1888H	Substitution - Missense	Large_intestine
COSM1936499	c.3578G>A	p.R1193Q	Substitution - Missense	Large_intestine
COSM5721981	c.803C>T	p.T268I	Substitution - Missense	Skin
COSM694439	c.2099-1G>A	p.?	Unknown	Lung
COSM4794196	c.3744G>A	p.Q1248Q	Substitution - coding silent	Liver
COSM2151287	c.1487C>T	p.S496F	Substitution - Missense	Central_nervous_system
COSM5041914	c.844+1G>A	p.?	Unknown	Liver
COSM459432	c.4230C>G	p.F1410L	Substitution - Missense	Cervix
COSM941720	c.5772C>T	p.R1924R	Substitution - coding silent	Endometrium
COSM1936759	c.126C>T	p.F42F	Substitution - coding silent	Skin
COSM3376315	c.4795C>T	p.R1599W	Substitution - Missense	Pancreas
COSM4415207	c.52A>G	p.R18G	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5375649	c.2832C>T	p.L944L	Substitution - coding silent	Skin
COSM1936693	c.677T>C	p.V226A	Substitution - Missense	Large_intestine
COSM4168948	c.4375C>G	p.L1459V	Substitution - Missense	Liver
COSM1936630	c.1634G>A	p.R545H	Substitution - Missense	Large_intestine
COSM4168948	c.4375C>G	p.L1459V	Substitution - Missense	Liver
COSM5375654	c.107delA	p.N36fs*5	Deletion - Frameshift	Skin
COSM5492978	c.5333G>A	p.G1778D	Substitution - Missense	Biliary_tract
COSM4633699	c.3982G>T	p.A1328S	Substitution - Missense	Large_intestine
COSM3396081	c.4687C>T	p.R1563W	Substitution - Missense	Prostate
COSM5888146	c.341C>T	p.S114F	Substitution - Missense	Upper_aerodigestive_tract
COSM3463519	c.5007C>G	p.A1669A	Substitution - coding silent	Skin
COSM4043678	c.2204G>T	p.R735I	Substitution - Missense	Stomach
COSM1184484	c.364C>A	p.P122T	Substitution - Missense	Stomach
COSM1936478	c.4512G>A	p.W1504*	Substitution - Nonsense	Large_intestine
COSM5375643	c.5487G>A	p.R1829R	Substitution - coding silent	Skin
COSM3987081	c.1039A>T	p.N347Y	Substitution - Missense	Kidney
COSM4466823	c.1562C>T	p.P521L	Substitution - Missense	Skin
COSM3463563	c.191C>T	p.S64F	Substitution - Missense	Skin
COSM5964670	c.3370C>T	p.R1124C	Substitution - Missense	Breast
COSM5492976	c.5225G>A	p.G1742D	Substitution - Missense	Biliary_tract
COSM1936736	c.458C>T	p.S153L	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM941771	c.1715G>A	p.R572Q	Substitution - Missense	Endometrium
COSM431535	c.3125delA	p.K1042fs*11	Deletion - Frameshift	Breast
COSM941729	c.4672G>A	p.D1558N	Substitution - Missense	Endometrium
COSM5691198	c.91G>A	p.E31K	Substitution - Missense	Soft_tissue
COSM1363143	c.356_357insG	p.Q120fs*20	Insertion - Frameshift	Large_intestine
COSM4444424	c.2168G>A	p.R723Q	Substitution - Missense	Large_intestine
COSM1606396	c.3184A>G	p.I1062V	Substitution - Missense	Liver
COSM4961486	c.2979C>T	p.R993R	Substitution - coding silent	Liver
COSM5987480	c.2034G>C	p.K678N	Substitution - Missense	Salivary_gland
COSM431538	c.1073T>G	p.L358R	Substitution - Missense	Breast
COSM941735	c.4287G>A	p.Q1429Q	Substitution - coding silent	Endometrium
COSM4043658	c.5006+1G>A	p.?	Unknown	Stomach
COSM694445	c.4541A>T	p.D1514V	Substitution - Missense	Lung
COSM4796745	c.2389G>A	p.G797R	Substitution - Missense	Liver
COSM3376317	c.4903C>T	p.R1635W	Substitution - Missense	Pancreas
COSM3376317	c.4903C>T	p.R1635W	Substitution - Missense	Pancreas
COSM1936694	c.785T>C	p.V262A	Substitution - Missense	Large_intestine
COSM5576437	c.567C>T	p.S189S	Substitution - coding silent	Skin
COSM4949780	c.5053G>T	p.G1685C	Substitution - Missense	Liver
COSM941747	c.3427T>C	p.L1143L	Substitution - coding silent	Endometrium
COSM4665230	c.298T>C	p.S100P	Substitution - Missense	Large_intestine
COSM4494074	c.4374C>T	p.Y1458Y	Substitution - coding silent	Skin
COSM694433	c.736+1G>T	p.?	Unknown	Lung
COSM1476760	c.3176G>A	p.R1059Q	Substitution - Missense	Breast
COSM352463	c.503A>T	p.Q168L	Substitution - Missense	Lung
COSM4043660	c.4817T>C	p.L1606P	Substitution - Missense	Stomach
COSM4444424	c.2168G>A	p.R723Q	Substitution - Missense	Large_intestine
COSM5987482	c.2142G>C	p.K714N	Substitution - Missense	Salivary_gland
COSM1184478	c.2155C>T	p.Q719*	Substitution - Nonsense	Large_intestine
COSM1289803	c.2098+1G>A	p.?	Unknown	Haematopoietic_and_lymphoid_tissue
COSM4665231	c.406T>C	p.S136P	Substitution - Missense	Large_intestine
COSM5715134	c.526T>C	p.F176L	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1184483	c.4583G>T	p.R1528M	Substitution - Missense	Large_intestine
COSM1936500	c.3686G>A	p.R1229Q	Substitution - Missense	Large_intestine
COSM5015127	c.2167C>T	p.R723W	Substitution - Missense	Kidney
COSM941721	c.5548G>T	p.G1850*	Substitution - Nonsense	Endometrium
COSM4665225	c.4785C>T	p.S1595S	Substitution - coding silent	Large_intestine
COSM4665222	c.5032C>T	p.R1678C	Substitution - Missense	Large_intestine
COSM1184486	c.472C>A	p.P158T	Substitution - Missense	Stomach
COSM1363123	c.4626_4627insC	p.K1543fs*26	Insertion - Frameshift	Large_intestine
COSM4575599	c.4108G>T	p.A1370S	Substitution - Missense	Bone
COSM3463560	c.379T>G	p.C127G	Substitution - Missense	Skin
COSM5758773	c.768C>T	p.V256V	Substitution - coding silent	Bone
COSM3463564	c.77C>T	p.S26F	Substitution - Missense	Skin
COSM5141037	c.1925C>T	p.P642L	Substitution - Missense	Large_intestine
COSM4043688	c.1544C>A	p.A515E	Substitution - Missense	Stomach
COSM1936564	c.2601G>A	p.V867V	Substitution - coding silent	Large_intestine
COSM5416366	c.2445delG	p.M815fs*6	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM941780	c.1657C>T	p.R553C	Substitution - Missense	Endometrium
COSM941783	c.1366G>A	p.A456T	Substitution - Missense	Liver
COSM3772693	c.1336T>C	p.S446P	Substitution - Missense	Pancreas
COSM4043664	c.4652T>C	p.L1551P	Substitution - Missense	Stomach
COSM4427091	c.2179C>G	p.Q727E	Substitution - Missense	Oesophagus
COSM4643745	c.5502T>G	p.D1834E	Substitution - Missense	Large_intestine
COSM5416367	c.2553delG	p.M851fs*6	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM1299679	c.3409G>T	p.E1137*	Substitution - Nonsense	Urinary_tract
COSM941761	c.2745G>A	p.L915L	Substitution - coding silent	Endometrium
COSM1184489	c.5485C>T	p.R1829W	Substitution - Missense	Large_intestine
COSM1936430	c.5663G>A	p.R1888H	Substitution - Missense	Large_intestine
COSM941741	c.3710T>G	p.L1237R	Substitution - Missense	Endometrium
COSM5721980	c.695C>T	p.T232I	Substitution - Missense	Skin
COSM1936582	c.2142G>C	p.K714N	Substitution - Missense	Upper_aerodigestive_tract
COSM2151287	c.1487C>T	p.S496F	Substitution - Missense	Central_nervous_system
COSM1936445	c.5365C>T	p.R1789*	Substitution - Nonsense	Stomach
COSM4779912	c.459G>A	p.S153S	Substitution - coding silent	Liver
COSM1936606	c.1867G>T	p.E623*	Substitution - Nonsense	Skin
COSM941762	c.2518C>T	p.R840*	Substitution - Nonsense	Large_intestine
COSM3396079	c.4579C>T	p.R1527W	Substitution - Missense	Prostate
COSM5901770	c.2656C>T	p.L886F	Substitution - Missense	Skin
COSM352461	c.395A>T	p.Q132L	Substitution - Missense	Lung
COSM3463521	c.5115C>G	p.A1705A	Substitution - coding silent	Skin
COSM941718	c.5664C>T	p.R1888R	Substitution - coding silent	Endometrium
COSM5566349	c.1802G>A	p.R601H	Substitution - Missense	Prostate
COSM3987078	c.1298C>T	p.T433I	Substitution - Missense	Kidney
COSM3710797	c.3199G>T	p.G1067C	Substitution - Missense	Upper_aerodigestive_tract
COSM3710797	c.3199G>T	p.G1067C	Substitution - Missense	Upper_aerodigestive_tract
COSM4794194	c.3636G>A	p.Q1212Q	Substitution - coding silent	Liver
COSM4787722	c.2981A>G	p.K994R	Substitution - Missense	Liver
COSM5628756	c.4128_4129insC	p.A1377fs*4	Insertion - Frameshift	Oesophagus
COSM694435	c.844+1G>T	p.?	Unknown	Lung
COSM5375645	c.4797G>A	p.R1599R	Substitution - coding silent	Skin
COSM5042823	c.3236G>A	p.S1079N	Substitution - Missense	Liver
COSM5691199	c.199G>A	p.E67K	Substitution - Missense	Soft_tissue
COSM4043663	c.4544T>C	p.L1515P	Substitution - Missense	Stomach
COSM4987867	c.5351G>A	p.G1784D	Substitution - Missense	Soft_tissue
COSM4802779	c.3850C>T	p.L1284L	Substitution - coding silent	Liver
COSM3463548	c.919C>T	p.P307S	Substitution - Missense	Skin
COSM1936619	c.1826G>A	p.W609*	Substitution - Nonsense	Large_intestine
COSM941743	c.3818T>G	p.L1273R	Substitution - Missense	Endometrium
COSM1195721	c.1283C>T	p.A428V	Substitution - Missense	Lung
COSM3463530	c.3219C>T	p.C1073C	Substitution - coding silent	Skin
COSM1363137	c.2634C>T	p.S878S	Substitution - coding silent	Large_intestine
COSM5375639	c.5469C>T	p.N1823N	Substitution - coding silent	Skin
COSM941770	c.2406A>C	p.E802D	Substitution - Missense	Endometrium
COSM1476759	c.3068G>A	p.R1023Q	Substitution - Missense	Large_intestine
COSM4976410	c.4023A>G	p.A1341A	Substitution - coding silent	Oesophagus
COSM3396079	c.4579C>T	p.R1527W	Substitution - Missense	Prostate
COSM1936738	c.333C>T	p.P111P	Substitution - coding silent	Oesophagus
COSM4787724	c.3089A>G	p.K1030R	Substitution - Missense	Liver
COSM259607	c.1480A>C	p.K494Q	Substitution - Missense	Large_intestine
COSM5935841	c.532C>T	p.L178F	Substitution - Missense	Skin
COSM5758775	c.876C>T	p.V292V	Substitution - coding silent	Bone
COSM694441	c.2207-1G>A	p.?	Unknown	Lung
COSM3376315	c.4795C>T	p.R1599W	Substitution - Missense	Pancreas
COSM4778809	c.1249+10G>A	p.?	Unknown	Liver
COSM5051784	c.4023G>A	p.P1341P	Substitution - coding silent	Stomach
COSM5935839	c.424C>T	p.L142F	Substitution - Missense	Skin
COSM468684	c.863A>G	p.Y288C	Substitution - Missense	Kidney
COSM941728	c.5194G>A	p.G1732R	Substitution - Missense	Endometrium
COSM1936760	c.234C>T	p.F78F	Substitution - coding silent	Skin
COSM941740	c.4350C>A	p.F1450L	Substitution - Missense	Endometrium
COSM941723	c.5656G>T	p.G1886*	Substitution - Nonsense	Endometrium
COSM416141	c.3980C>G	p.S1327*	Substitution - Nonsense	Urinary_tract
COSM5434874	c.1877A>T	p.D626V	Substitution - Missense	Oesophagus
COSM1936631	c.1742G>A	p.R581H	Substitution - Missense	Large_intestine
COSM3396084	c.4686G>T	p.Q1562H	Substitution - Missense	Prostate
COSM5574425	c.2425_2426delAA	p.K809fs*23	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM459433	c.4726C>T	p.Q1576*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM4043691	c.675C>A	p.S225S	Substitution - coding silent	Stomach
COSM5375651	c.2072G>C	p.R691P	Substitution - Missense	Skin
COSM5012579	c.3942C>A	p.S1314R	Substitution - Missense	Kidney
COSM3710799	c.3307G>T	p.G1103C	Substitution - Missense	Upper_aerodigestive_tract
COSM3739782	c.5620A>G	p.M1874V	Substitution - Missense	Liver
COSM5888148	c.449C>T	p.S150F	Substitution - Missense	Upper_aerodigestive_tract
COSM3463558	c.271T>G	p.C91G	Substitution - Missense	Skin
COSM1476760	c.3176G>A	p.R1059Q	Substitution - Missense	Large_intestine

> Text Mining based Variations [ TOP ]
There is no record for BAZ2A.

Summary
Symbol	BAZ2A
Name	bromodomain adjacent to zinc finger domain 2A
Aliases	KIAA0314; TIP5; WALp3; TTF-I interacting peptide 5; TTF-I-interacting protein 5; transcription termination f ......
Location	12q13.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

[ TOP ]

Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant
Q9UIF9	509	S	Phosphoserine	-	No	None detected
Q9UIF9	548	T	Phosphothreonine	-	No	None detected
Q9UIF9	613	S	Phosphoserine	-	No	None detected
Q9UIF9	680	K	N6-acetyllysine	KAT8	No	None detected
Q9UIF9	799	K	N6-acetyllysine	-	No	None detected
Q9UIF9	1051	S	Phosphoserine	-	No	None detected
Q9UIF9	1184	S	Phosphoserine	-	No	None detected
Q9UIF9	1397	S	Phosphoserine	-	No	None detected
Q9UIF9	1559	S	Phosphoserine	-	No	None detected
Q9UIF9	1747	S	Phosphoserine	-	No	None detected
Q9UIF9	1770	S	Phosphoserine	-	No	None detected
Q9UIF9	1783	S	Phosphoserine	-	No	None detected
Q9UIF9	1785	S	Phosphoserine	-	No	None detected

Summary
Symbol	BAZ2A
Name	bromodomain adjacent to zinc finger domain 2A
Aliases	KIAA0314; TIP5; WALp3; TTF-I interacting peptide 5; TTF-I-interacting protein 5; transcription termination f ......
Location	12q13.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	6.78	6.778	0.007	0.967	NS
BRCA	Breast invasive carcinoma	112	1100	7.257	7.23	-0.012	0.841	NS
CESC	Cervical and endocervical cancers	3	306	6.436	6.828	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	7.232	6.991	-0.19	0.0258	NS
ESCA	Esophageal carcinoma	11	185	7.18	7.503	0.224	0.147	NS
GBM	Glioblastoma multiforme	5	166	6.411	6.018	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	6.703	6.974	0.138	0.151	NS
KIRC	Kidney renal clear cell carcinoma	72	534	6.986	7.179	0.207	0.000178	NS
KIRP	Kidney renal papillary cell carcinoma	32	291	6.899	6.951	0.052	0.631	NS
LAML	Acute Myeloid Leukemia	0	173	NA	8.368	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	6.612	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	5.089	5.497	0.463	1.17e-07	NS
LUAD	Lung adenocarcinoma	59	517	7.179	7.162	0.104	0.228	NS
LUSC	Lung squamous cell carcinoma	51	501	7.133	7.135	0.031	0.69	NS
OV	Ovarian serous cystadenocarcinoma	0	307	NA	7.381	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	6.741	6.988	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	6.469	6.963	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	6.775	6.851	0.124	0.137	NS
READ	Rectum adenocarcinoma	10	167	6.981	6.989	0.05	0.819	NS
SARC	Sarcoma	2	263	5.727	6.223	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	6.908	7.077	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	7.247	7.302	0.153	0.0668	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	7.501	NA	NA	NA
THCA	Thyroid carcinoma	59	509	6.871	6.919	0.096	0.105	NS
THYM	Thymoma	2	120	7.686	6.864	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	6.577	6.453	-0.099	0.3	NS

> Cancer Cell Line Encyclopedia (CCLE)

[ TOP ]

Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	6.5
Autonomic ganglia	CHP212	6.1
Autonomic ganglia	IMR32	6.8
Autonomic ganglia	KELLY	6.4
Autonomic ganglia	KPNRTBM1	6.2
Autonomic ganglia	KPNSI9S	6
Autonomic ganglia	KPNYN	6.2
Autonomic ganglia	MHHNB11	7.3
Autonomic ganglia	NB1	6.6
Autonomic ganglia	NH6	5.8
Autonomic ganglia	SHSY5Y	6.6
Autonomic ganglia	SIMA	7
Autonomic ganglia	SKNAS	6.2
Autonomic ganglia	SKNBE2	6.1
Autonomic ganglia	SKNDZ	6.2
Autonomic ganglia	SKNFI	6.6
Autonomic ganglia	SKNSH	6
Biliary tract	HUCCT1	6.1
Biliary tract	HUH28	6.2
Biliary tract	SNU1079	6.7
Biliary tract	SNU1196	6.4
Biliary tract	SNU245	6.5
Biliary tract	SNU308	6.9
Biliary tract	SNU478	6.7
Bone	143B	6.4
Bone	A673	6.4
Bone	CADOES1	6.7
Bone	CAL78	5.7
Bone	G292CLONEA141B1	5.9
Bone	HOS	6.4
Bone	HS706T	6
Bone	HS737T	6
Bone	HS819T	5.9
Bone	HS821T	5.8
Bone	HS822T	6
Bone	HS863T	5.9
Bone	HS870T	5.6
Bone	HS888T	6.3
Bone	MG63	5.9
Bone	MHHES1	7.2
Bone	OUMS27	6
Bone	RDES	6.8
Bone	SJSA1	6.1
Bone	SKES1	6.4
Bone	SKNMC	6.8
Bone	SW1353	6.1
Bone	T173	5.6
Bone	TC71	6.5
Bone	U2OS	6.5
Breast	AU565	6.6
Breast	BT20	6.4
Breast	BT474	6.5
Breast	BT483	7
Breast	BT549	6.2
Breast	CAL120	6.2
Breast	CAL148	6.5
Breast	CAL51	6.4
Breast	CAL851	6.3
Breast	CAMA1	6.3
Breast	DU4475	6.6
Breast	EFM192A	6.6
Breast	EFM19	6.5
Breast	EVSAT	6.5
Breast	HCC1143	7.1
Breast	HCC1187	6.3
Breast	HCC1395	6.3
Breast	HCC1419	6.9
Breast	HCC1428	6.7
Breast	HCC1500	6.2
Breast	HCC1569	6.7
Breast	HCC1599	6.4
Breast	HCC1806	6.7
Breast	HCC1937	6.2
Breast	HCC1954	6
Breast	HCC202	6.7
Breast	HCC2157	6.5
Breast	HCC2218	6.5
Breast	HCC38	6.2
Breast	HCC70	6.3
Breast	HDQP1	6.4
Breast	HMC18	6.6
Breast	HS274T	6
Breast	HS281T	5.9
Breast	HS343T	5.8
Breast	HS578T	6
Breast	HS606T	5.6
Breast	HS739T	5.9
Breast	HS742T	5.8
Breast	JIMT1	6.2
Breast	KPL1	6.5
Breast	MCF7	6.3
Breast	MDAMB134VI	7
Breast	MDAMB157	6.2
Breast	MDAMB175VII	6.5
Breast	MDAMB231	6.1
Breast	MDAMB361	6.4
Breast	MDAMB415	6.6
Breast	MDAMB436	6.1
Breast	MDAMB453	6.7
Breast	MDAMB468	6
Breast	SKBR3	6.8
Breast	T47D	6.5
Breast	UACC812	7.3
Breast	UACC893	6.8
Breast	YMB1	6.5
Breast	ZR751	6.2
Breast	ZR7530	6.8
Central nervous system	1321N1	5.9
Central nervous system	42MGBA	5.5
Central nervous system	8MGBA	5.8
Central nervous system	A172	5.9
Central nervous system	AM38	5.9
Central nervous system	BECKER	5.9
Central nervous system	CAS1	6
Central nervous system	CCFSTTG1	6.2
Central nervous system	D283MED	6.1
Central nervous system	D341MED	6.6
Central nervous system	DAOY	6
Central nervous system	DBTRG05MG	6
Central nervous system	DKMG	5.7
Central nervous system	GAMG	5.8
Central nervous system	GB1	7.2
Central nervous system	GI1	5.8
Central nervous system	GMS10	5.7
Central nervous system	GOS3	6.3
Central nervous system	H4	6.3
Central nervous system	HS683	5.9
Central nervous system	KALS1	5.9
Central nervous system	KG1C	6.1
Central nervous system	KNS42	5.8
Central nervous system	KNS60	5.8
Central nervous system	KNS81	5.8
Central nervous system	KS1	5.8
Central nervous system	LN18	6.4
Central nervous system	LN229	5.9
Central nervous system	M059K	5.9
Central nervous system	MOGGCCM	5.9
Central nervous system	MOGGUVW	6.3
Central nervous system	NMCG1	5.7
Central nervous system	ONS76	6.3
Central nervous system	SF126	5.7
Central nervous system	SF295	5.9
Central nervous system	SNB19	5.8
Central nervous system	SNU1105	6.1
Central nervous system	SNU201	6.1
Central nervous system	SNU466	6.6
Central nervous system	SNU489	6.3
Central nervous system	SNU626	6.1
Central nervous system	SNU738	6.5
Central nervous system	SW1088	6.2
Central nervous system	SW1783	5.7
Central nervous system	T98G	6
Central nervous system	TM31	6.3
Central nervous system	U118MG	6.5
Central nervous system	U138MG	6.1
Central nervous system	U251MG	5.7
Central nervous system	U87MG	6.1
Central nervous system	YH13	5.9
Central nervous system	YKG1	5.8
Endometrium	AN3CA	6.5
Endometrium	COLO684	6.8
Endometrium	EFE184	6.8
Endometrium	EN	6.4
Endometrium	ESS1	6.2
Endometrium	HEC108	6.3
Endometrium	HEC151	6.7
Endometrium	HEC1A	6.4
Endometrium	HEC1B	6.9
Endometrium	HEC251	6.3
Endometrium	HEC265	6.5
Endometrium	HEC50B	6.2
Endometrium	HEC59	6.2
Endometrium	HEC6	6.1
Endometrium	ISHIKAWAHERAKLIO02ER	6.1
Endometrium	JHUEM1	6.7
Endometrium	JHUEM2	6.1
Endometrium	JHUEM3	6.4
Endometrium	KLE	6.3
Endometrium	MFE280	6.8
Endometrium	MFE296	6.2
Endometrium	MFE319	6.7
Endometrium	RL952	6.7
Endometrium	SNGM	6.7
Endometrium	SNU1077	6.9
Endometrium	SNU685	6.4
Endometrium	TEN	6.4
Haematopoietic and lymphoid	697	6.6
Haematopoietic and lymphoid	A3KAW	6.7
Haematopoietic and lymphoid	A4FUK	7.6
Haematopoietic and lymphoid	ALLSIL	6.5
Haematopoietic and lymphoid	AML193	6.6
Haematopoietic and lymphoid	AMO1	6.8
Haematopoietic and lymphoid	BCP1	6.7
Haematopoietic and lymphoid	BDCM	6.2
Haematopoietic and lymphoid	BL41	6.7
Haematopoietic and lymphoid	BL70	6.4
Haematopoietic and lymphoid	BV173	7.2
Haematopoietic and lymphoid	CA46	6.9
Haematopoietic and lymphoid	CI1	6.8
Haematopoietic and lymphoid	CMK115	6.1
Haematopoietic and lymphoid	CMK86	6.8
Haematopoietic and lymphoid	CMK	6.4
Haematopoietic and lymphoid	CMLT1	6.6
Haematopoietic and lymphoid	COLO775	7
Haematopoietic and lymphoid	DAUDI	6.7
Haematopoietic and lymphoid	DB	6.4
Haematopoietic and lymphoid	DEL	6.8
Haematopoietic and lymphoid	DND41	6.8
Haematopoietic and lymphoid	DOHH2	6.6
Haematopoietic and lymphoid	EB1	6.7
Haematopoietic and lymphoid	EB2	6.5
Haematopoietic and lymphoid	EHEB	6.8
Haematopoietic and lymphoid	EJM	6.8
Haematopoietic and lymphoid	EM2	6.5
Haematopoietic and lymphoid	EOL1	6.3
Haematopoietic and lymphoid	F36P	6.6
Haematopoietic and lymphoid	GA10	6.6
Haematopoietic and lymphoid	GDM1	6.6
Haematopoietic and lymphoid	GRANTA519	6.9
Haematopoietic and lymphoid	HDLM2	6.7
Haematopoietic and lymphoid	HDMYZ	5.8
Haematopoietic and lymphoid	HEL9217	6.5
Haematopoietic and lymphoid	HEL	6.7
Haematopoietic and lymphoid	HH	6.6
Haematopoietic and lymphoid	HL60	7.2
Haematopoietic and lymphoid	HPBALL	6.9
Haematopoietic and lymphoid	HS604T	6.3
Haematopoietic and lymphoid	HS611T	6.4
Haematopoietic and lymphoid	HS616T	5.9
Haematopoietic and lymphoid	HS751T	5.4
Haematopoietic and lymphoid	HT	6.5
Haematopoietic and lymphoid	HTK	6.7
Haematopoietic and lymphoid	HUNS1	6.3
Haematopoietic and lymphoid	HUT102	6.3
Haematopoietic and lymphoid	HUT78	6.2
Haematopoietic and lymphoid	JEKO1	7.5
Haematopoietic and lymphoid	JK1	6.8
Haematopoietic and lymphoid	JM1	7.1
Haematopoietic and lymphoid	JURKAT	6.2
Haematopoietic and lymphoid	JURLMK1	6.8
Haematopoietic and lymphoid	JVM2	7.7
Haematopoietic and lymphoid	JVM3	7.4
Haematopoietic and lymphoid	K562	6.7
Haematopoietic and lymphoid	KARPAS299	6.8
Haematopoietic and lymphoid	KARPAS422	6.5
Haematopoietic and lymphoid	KARPAS620	7
Haematopoietic and lymphoid	KASUMI1	5.9
Haematopoietic and lymphoid	KASUMI2	6.6
Haematopoietic and lymphoid	KASUMI6	6.7
Haematopoietic and lymphoid	KCL22	6.7
Haematopoietic and lymphoid	KE37	6.4
Haematopoietic and lymphoid	KE97	6.4
Haematopoietic and lymphoid	KG1	6.1
Haematopoietic and lymphoid	KHM1B	6.4
Haematopoietic and lymphoid	KIJK	6.3
Haematopoietic and lymphoid	KMH2	7.1
Haematopoietic and lymphoid	KMM1	6.9
Haematopoietic and lymphoid	KMS11	7.1
Haematopoietic and lymphoid	KMS12BM	7
Haematopoietic and lymphoid	KMS18	6.8
Haematopoietic and lymphoid	KMS20	6.6
Haematopoietic and lymphoid	KMS21BM	6.5
Haematopoietic and lymphoid	KMS26	6.2
Haematopoietic and lymphoid	KMS27	6.3
Haematopoietic and lymphoid	KMS28BM	6.6
Haematopoietic and lymphoid	KMS34	7.1
Haematopoietic and lymphoid	KO52	6.4
Haematopoietic and lymphoid	KOPN8	7
Haematopoietic and lymphoid	KU812	6.1
Haematopoietic and lymphoid	KYO1	6.3
Haematopoietic and lymphoid	L1236	6.8
Haematopoietic and lymphoid	L363	6.8
Haematopoietic and lymphoid	L428	7.2
Haematopoietic and lymphoid	L540	6.8
Haematopoietic and lymphoid	LAMA84	6.7
Haematopoietic and lymphoid	LOUCY	6
Haematopoietic and lymphoid	LP1	6.9
Haematopoietic and lymphoid	M07E	6.5
Haematopoietic and lymphoid	MC116	6.5
Haematopoietic and lymphoid	ME1	6.9
Haematopoietic and lymphoid	MEC1	6.6
Haematopoietic and lymphoid	MEC2	7
Haematopoietic and lymphoid	MEG01	6.1
Haematopoietic and lymphoid	MHHCALL2	6.2
Haematopoietic and lymphoid	MHHCALL3	6.7
Haematopoietic and lymphoid	MHHCALL4	6.6
Haematopoietic and lymphoid	MINO	6.5
Haematopoietic and lymphoid	MJ	6.3
Haematopoietic and lymphoid	MM1S	6.7
Haematopoietic and lymphoid	MOLM13	6.4
Haematopoietic and lymphoid	MOLM16	6.7
Haematopoietic and lymphoid	MOLM6	6.6
Haematopoietic and lymphoid	MOLP2	7
Haematopoietic and lymphoid	MOLP8	6.9
Haematopoietic and lymphoid	MOLT13	6.7
Haematopoietic and lymphoid	MOLT16	6.4
Haematopoietic and lymphoid	MOLT4	6.1
Haematopoietic and lymphoid	MONOMAC1	6.8
Haematopoietic and lymphoid	MONOMAC6	6.4
Haematopoietic and lymphoid	MOTN1	7
Haematopoietic and lymphoid	MUTZ5	6.7
Haematopoietic and lymphoid	MV411	6.7
Haematopoietic and lymphoid	NALM19	6.7
Haematopoietic and lymphoid	NALM1	6.8
Haematopoietic and lymphoid	NALM6	6.8
Haematopoietic and lymphoid	NAMALWA	7.3
Haematopoietic and lymphoid	NB4	6.9
Haematopoietic and lymphoid	NCIH929	6.3
Haematopoietic and lymphoid	NCO2	6.1
Haematopoietic and lymphoid	NOMO1	6.5
Haematopoietic and lymphoid	NUDHL1	7.4
Haematopoietic and lymphoid	NUDUL1	7.2
Haematopoietic and lymphoid	OCIAML2	6.3
Haematopoietic and lymphoid	OCIAML3	7
Haematopoietic and lymphoid	OCIAML5	6.3
Haematopoietic and lymphoid	OCILY10	6.5
Haematopoietic and lymphoid	OCILY19	7.1
Haematopoietic and lymphoid	OCILY3	6.5
Haematopoietic and lymphoid	OCIM1	6.5
Haematopoietic and lymphoid	OPM2	6.9
Haematopoietic and lymphoid	P12ICHIKAWA	6.9
Haematopoietic and lymphoid	P31FUJ	6.1
Haematopoietic and lymphoid	P3HR1	6.7
Haematopoietic and lymphoid	PCM6	6.5
Haematopoietic and lymphoid	PEER	6.2
Haematopoietic and lymphoid	PF382	6.8
Haematopoietic and lymphoid	PFEIFFER	6.8
Haematopoietic and lymphoid	PL21	6.6
Haematopoietic and lymphoid	RAJI	6.8
Haematopoietic and lymphoid	RCHACV	6.6
Haematopoietic and lymphoid	REC1	7.5
Haematopoietic and lymphoid	REH	6.5
Haematopoietic and lymphoid	RI1	7.1
Haematopoietic and lymphoid	RL	6.5
Haematopoietic and lymphoid	RPMI8226	7
Haematopoietic and lymphoid	RPMI8402	6.5
Haematopoietic and lymphoid	RS411	6.3
Haematopoietic and lymphoid	SEM	6.1
Haematopoietic and lymphoid	SET2	6.6
Haematopoietic and lymphoid	SIGM5	6.8
Haematopoietic and lymphoid	SKM1	5.9
Haematopoietic and lymphoid	SKMM2	7.1
Haematopoietic and lymphoid	SR786	6.5
Haematopoietic and lymphoid	ST486	6.2
Haematopoietic and lymphoid	SUDHL10	6.9
Haematopoietic and lymphoid	SUDHL1	6.5
Haematopoietic and lymphoid	SUDHL4	7.1
Haematopoietic and lymphoid	SUDHL5	6.7
Haematopoietic and lymphoid	SUDHL6	6.6
Haematopoietic and lymphoid	SUDHL8	7.5
Haematopoietic and lymphoid	SUPB15	6.5
Haematopoietic and lymphoid	SUPHD1	6.8
Haematopoietic and lymphoid	SUPM2	6.4
Haematopoietic and lymphoid	SUPT11	6.7
Haematopoietic and lymphoid	SUPT1	6.3
Haematopoietic and lymphoid	TALL1	6.3
Haematopoietic and lymphoid	TF1	6.5
Haematopoietic and lymphoid	THP1	6.4
Haematopoietic and lymphoid	TO175T	5.9
Haematopoietic and lymphoid	TOLEDO	6.6
Haematopoietic and lymphoid	U266B1	6
Haematopoietic and lymphoid	U937	6.3
Haematopoietic and lymphoid	UT7	6.9
Haematopoietic and lymphoid	WSUDLCL2	6.6
Kidney	769P	6.3
Kidney	786O	6.3
Kidney	A498	6.4
Kidney	A704	6.3
Kidney	ACHN	6.6
Kidney	BFTC909	6.6
Kidney	CAKI1	6.1
Kidney	CAKI2	6.4
Kidney	CAL54	6.7
Kidney	KMRC1	6.3
Kidney	KMRC20	6.3
Kidney	KMRC2	6.2
Kidney	KMRC3	6.2
Kidney	OSRC2	6.2
Kidney	RCC10RGB	6.5
Kidney	SNU1272	6.5
Kidney	SNU349	6.5
Kidney	TUHR10TKB	6.4
Kidney	TUHR14TKB	6.7
Kidney	TUHR4TKB	6.7
Kidney	VMRCRCW	6.4
Kidney	VMRCRCZ	6.6
Large intestine	C2BBE1	6.3
Large intestine	CCK81	6.6
Large intestine	CL11	6.5
Large intestine	CL14	7.1
Large intestine	CL34	6.5
Large intestine	CL40	7.2
Large intestine	COLO205	6
Large intestine	COLO320	7.1
Large intestine	COLO678	6.8
Large intestine	CW2	6.4
Large intestine	DLD1	6.6
Large intestine	GP2D	6.1
Large intestine	HCC56	6.4
Large intestine	HCT116	6.5
Large intestine	HCT15	6.6
Large intestine	HS675T	5.9
Large intestine	HS698T	6
Large intestine	HT115	6.9
Large intestine	HT29	6.7
Large intestine	HT55	6.3
Large intestine	KM12	6.2
Large intestine	LOVO	6.6
Large intestine	LS1034	6.5
Large intestine	LS123	6.6
Large intestine	LS180	6.2
Large intestine	LS411N	6.3
Large intestine	LS513	5.8
Large intestine	MDST8	6.2
Large intestine	NCIH508	6.7
Large intestine	NCIH716	6.4
Large intestine	NCIH747	6.6
Large intestine	OUMS23	6.9
Large intestine	RCM1	6.9
Large intestine	RKO	6.3
Large intestine	SKCO1	6.4
Large intestine	SNU1040	6.8
Large intestine	SNU1197	6.8
Large intestine	SNU175	6.4
Large intestine	SNU283	6.9
Large intestine	SNU407	6.8
Large intestine	SNU503	6.9
Large intestine	SNU61	6.6
Large intestine	SNU81	6.3
Large intestine	SNUC1	6.5
Large intestine	SNUC2A	6.5
Large intestine	SNUC4	6.4
Large intestine	SNUC5	6.8
Large intestine	SW1116	6.8
Large intestine	SW1417	6.5
Large intestine	SW1463	6.8
Large intestine	SW403	6.4
Large intestine	SW480	6.7
Large intestine	SW48	6.3
Large intestine	SW620	6.6
Large intestine	SW837	6.4
Large intestine	SW948	6.5
Large intestine	T84	6.7
Liver	ALEXANDERCELLS	6.4
Liver	C3A	6.4
Liver	HEP3B217	6.4
Liver	HEPG2	6.4
Liver	HLE	6.2
Liver	HLF	6.3
Liver	HUH1	6.7
Liver	HUH6	7.1
Liver	HUH7	6.4
Liver	JHH1	6.7
Liver	JHH2	6.2
Liver	JHH4	6.6
Liver	JHH5	6.4
Liver	JHH6	5.5
Liver	JHH7	6.7
Liver	LI7	6.4
Liver	PLCPRF5	6.5
Liver	SKHEP1	6
Liver	SNU182	6.1
Liver	SNU387	6.1
Liver	SNU398	6.5
Liver	SNU423	6
Liver	SNU449	6.1
Liver	SNU475	6.4
Liver	SNU761	6.5
Liver	SNU878	6.2
Liver	SNU886	6.5
Lung	A549	6.3
Lung	ABC1	6.7
Lung	BEN	6.7
Lung	CAL12T	6.2
Lung	CALU1	6.1
Lung	CALU3	6.7
Lung	CALU6	6.6
Lung	CHAGOK1	6
Lung	COLO668	6.6
Lung	COLO699	6.7
Lung	CORL105	6.2
Lung	CORL23	6.6
Lung	CORL24	5.8
Lung	CORL279	6.6
Lung	CORL311	6.5
Lung	CORL47	6.2
Lung	CORL51	6.3
Lung	CORL88	6
Lung	CORL95	6.4
Lung	CPCN	6.3
Lung	DMS114	6.6
Lung	DMS153	6.3
Lung	DMS273	6.3
Lung	DMS454	6.3
Lung	DMS53	6.1
Lung	DMS79	5.3
Lung	DV90	6.5
Lung	EBC1	6.1
Lung	EPLC272H	6.2
Lung	HARA	6.5
Lung	HCC1171	6.2
Lung	HCC1195	7
Lung	HCC15	6.3
Lung	HCC2279	6.2
Lung	HCC2935	6.2
Lung	HCC33	6.4
Lung	HCC366	5.8
Lung	HCC4006	6.2
Lung	HCC44	6.6
Lung	HCC78	6.3
Lung	HCC827	6.6
Lung	HCC95	6
Lung	HLC1	6.6
Lung	HLFA	6.1
Lung	HS229T	6
Lung	HS618T	6.2
Lung	IALM	6.9
Lung	KNS62	6.4
Lung	LC1F	6.6
Lung	LC1SQSF	6.1
Lung	LCLC103H	6.1
Lung	LCLC97TM1	6.8
Lung	LK2	6.5
Lung	LOUNH91	6.3
Lung	LU65	6.3
Lung	LU99	6.3
Lung	LUDLU1	6.4
Lung	LXF289	6.5
Lung	MORCPR	6.9
Lung	NCIH1048	6
Lung	NCIH1092	5.5
Lung	NCIH1105	5.8
Lung	NCIH1155	5.8
Lung	NCIH1184	6.2
Lung	NCIH1299	6.7
Lung	NCIH1339	6.4
Lung	NCIH1341	6.1
Lung	NCIH1355	6.3
Lung	NCIH1373	6.3
Lung	NCIH1385	7.4
Lung	NCIH1395	6.7
Lung	NCIH1435	6.6
Lung	NCIH1436	6
Lung	NCIH1437	7.1
Lung	NCIH146	6.3
Lung	NCIH1563	6.1
Lung	NCIH1568	6.6
Lung	NCIH1573	6.8
Lung	NCIH1581	7.1
Lung	NCIH1618	6.2
Lung	NCIH1623	6.8
Lung	NCIH1648	6.5
Lung	NCIH1650	6.5
Lung	NCIH1651	6.4
Lung	NCIH1666	6.5
Lung	NCIH1693	6.1
Lung	NCIH1694	5.9
Lung	NCIH1703	6.2
Lung	NCIH1734	6.4
Lung	NCIH1755	5.8
Lung	NCIH1781	6.6
Lung	NCIH1792	6.1
Lung	NCIH1793	6.2
Lung	NCIH1836	6.4
Lung	NCIH1838	6.2
Lung	NCIH1869	6.4
Lung	NCIH1876	6.3
Lung	NCIH1915	5.8
Lung	NCIH1930	6.2
Lung	NCIH1944	6.2
Lung	NCIH1963	6.3
Lung	NCIH196	5.9
Lung	NCIH1975	6.4
Lung	NCIH2009	6.4
Lung	NCIH2023	6
Lung	NCIH2029	6.6
Lung	NCIH2030	6.4
Lung	NCIH2066	6.5
Lung	NCIH2081	6
Lung	NCIH2085	6.4
Lung	NCIH2087	6.5
Lung	NCIH209	6.2
Lung	NCIH2106	5.7
Lung	NCIH2110	5.7
Lung	NCIH211	6.4
Lung	NCIH2122	6.5
Lung	NCIH2126	6.8
Lung	NCIH2141	6.6
Lung	NCIH2170	6.4
Lung	NCIH2171	6.4
Lung	NCIH2172	5.8
Lung	NCIH2196	6.5
Lung	NCIH2227	5.9
Lung	NCIH2228	6
Lung	NCIH226	6.1
Lung	NCIH2286	6.5
Lung	NCIH2291	6.5
Lung	NCIH2342	6.7
Lung	NCIH2347	6.1
Lung	NCIH23	7
Lung	NCIH2405	6.2
Lung	NCIH2444	6.9
Lung	NCIH292	6.5
Lung	NCIH322	6.5
Lung	NCIH3255	6.6
Lung	NCIH358	6.6
Lung	NCIH441	6.5
Lung	NCIH446	6.4
Lung	NCIH460	6.3
Lung	NCIH510	6.3
Lung	NCIH520	6.5
Lung	NCIH522	6.4
Lung	NCIH524	6.2
Lung	NCIH526	6.5
Lung	NCIH596	6.1
Lung	NCIH647	6.1
Lung	NCIH650	6.4
Lung	NCIH661	6.7
Lung	NCIH69	6.1
Lung	NCIH727	6.5
Lung	NCIH810	6.8
Lung	NCIH82	6.9
Lung	NCIH838	6.2
Lung	NCIH841	6.5
Lung	NCIH854	6.7
Lung	NCIH889	6.4
Lung	PC14	6.5
Lung	RERFLCAD1	6.4
Lung	RERFLCAD2	6.3
Lung	RERFLCAI	6.1
Lung	RERFLCKJ	6.2
Lung	RERFLCMS	6.3
Lung	RERFLCSQ1	5.7
Lung	SBC5	6.1
Lung	SCLC21H	6.8
Lung	SHP77	6.4
Lung	SKLU1	6.7
Lung	SKMES1	6.3
Lung	SQ1	6.5
Lung	SW1271	6.9
Lung	SW1573	6.4
Lung	SW900	6.3
Lung	VMRCLCD	7.5
Lung	VMRCLCP	6.6
Oesophagus	COLO680N	6.9
Oesophagus	ECGI10	6.9
Oesophagus	KYSE140	6.7
Oesophagus	KYSE150	6.6
Oesophagus	KYSE180	6.4
Oesophagus	KYSE270	6.5
Oesophagus	KYSE30	6.8
Oesophagus	KYSE410	6.9
Oesophagus	KYSE450	6.4
Oesophagus	KYSE510	6.3
Oesophagus	KYSE520	6.6
Oesophagus	KYSE70	6.2
Oesophagus	OE19	6.6
Oesophagus	OE33	6.6
Oesophagus	TE10	7.2
Oesophagus	TE11	6.5
Oesophagus	TE14	6.9
Oesophagus	TE15	6.7
Oesophagus	TE1	6.1
Oesophagus	TE4	6.4
Oesophagus	TE5	6.7
Oesophagus	TE6	6.6
Oesophagus	TE8	6.6
Oesophagus	TE9	6.3
Oesophagus	TT	6.3
Ovary	59M	6.4
Ovary	A2780	6.5
Ovary	CAOV3	6.4
Ovary	CAOV4	6.4
Ovary	COLO704	6.2
Ovary	COV318	6.9
Ovary	COV362	6
Ovary	COV434	6
Ovary	COV504	5.8
Ovary	COV644	6.3
Ovary	EFO21	6.6
Ovary	EFO27	6.6
Ovary	ES2	6.1
Ovary	FUOV1	6.6
Ovary	HEYA8	6.1
Ovary	HS571T	6.3
Ovary	IGROV1	6.5
Ovary	JHOC5	6.4
Ovary	JHOM1	6.2
Ovary	JHOM2B	6.6
Ovary	JHOS2	6.2
Ovary	JHOS4	6.4
Ovary	KURAMOCHI	6.6
Ovary	MCAS	6.3
Ovary	NIHOVCAR3	6.4
Ovary	OAW28	6.5
Ovary	OAW42	6.6
Ovary	OC314	6.7
Ovary	OC316	6.6
Ovary	ONCODG1	6.7
Ovary	OV56	6.7
Ovary	OV7	6.2
Ovary	OV90	6.6
Ovary	OVCAR4	6.6
Ovary	OVCAR8	6.3
Ovary	OVISE	6.1
Ovary	OVK18	6.5
Ovary	OVKATE	6.3
Ovary	OVMANA	7.2
Ovary	OVSAHO	6.4
Ovary	OVTOKO	6.5
Ovary	RMGI	6.8
Ovary	RMUGS	6.3
Ovary	SKOV3	6.2
Ovary	SNU119	6.5
Ovary	SNU840	6.4
Ovary	SNU8	6.6
Ovary	TOV112D	6.5
Ovary	TOV21G	6.3
Ovary	TYKNU	6.2
Pancreas	ASPC1	6.8
Pancreas	BXPC3	6.4
Pancreas	CAPAN1	6.8
Pancreas	CAPAN2	6.6
Pancreas	CFPAC1	7.1
Pancreas	DANG	5.9
Pancreas	HPAC	7
Pancreas	HPAFII	7
Pancreas	HS766T	6.4
Pancreas	HUPT3	6.7
Pancreas	HUPT4	6.9
Pancreas	KCIMOH1	6.3
Pancreas	KLM1	7
Pancreas	KP2	6.3
Pancreas	KP3	6.2
Pancreas	KP4	6.4
Pancreas	L33	6.7
Pancreas	MIAPACA2	6.8
Pancreas	PANC0203	6.9
Pancreas	PANC0213	6.5
Pancreas	PANC0327	7
Pancreas	PANC0403	6.5
Pancreas	PANC0504	6.4
Pancreas	PANC0813	6.3
Pancreas	PANC1005	6.7
Pancreas	PANC1	6.5
Pancreas	PATU8902	6.3
Pancreas	PATU8988S	6.5
Pancreas	PATU8988T	6.5
Pancreas	PK1	6.5
Pancreas	PK45H	6.3
Pancreas	PK59	6.8
Pancreas	PL45	6.6
Pancreas	PSN1	6.7
Pancreas	QGP1	6.4
Pancreas	SNU213	6.3
Pancreas	SNU324	6.8
Pancreas	SNU410	6.8
Pancreas	SU8686	6.6
Pancreas	SUIT2	6.6
Pancreas	SW1990	5.7
Pancreas	T3M4	6.8
Pancreas	TCCPAN2	6.6
Pancreas	YAPC	6.3
Pleura	ACCMESO1	5.7
Pleura	DM3	6.2
Pleura	ISTMES1	6.2
Pleura	ISTMES2	6.3
Pleura	JL1	6.6
Pleura	MPP89	6.1
Pleura	MSTO211H	6.3
Pleura	NCIH2052	6
Pleura	NCIH2452	6.2
Pleura	NCIH28	6.4
Prostate	22RV1	6.7
Prostate	DU145	6.1
Prostate	LNCAPCLONEFGC	5.9
Prostate	MDAPCA2B	6.4
Prostate	NCIH660	6.8
Prostate	PC3	6.4
Prostate	VCAP	6.4
Salivary gland	A253	6
Salivary gland	YD15	6.4
Skin	A101D	6.5
Skin	A2058	6.3
Skin	A375	6.3
Skin	C32	6.3
Skin	CHL1	6.3
Skin	CJM	6.7
Skin	COLO679	6.2
Skin	COLO741	6.3
Skin	COLO783	6.4
Skin	COLO792	6.1
Skin	COLO800	6.4
Skin	COLO818	6.4
Skin	COLO829	6.6
Skin	COLO849	6.4
Skin	G361	6.4
Skin	GRM	6.9
Skin	HMCB	6.2
Skin	HS294T	6.6
Skin	HS600T	5.8
Skin	HS688AT	6
Skin	HS695T	6.2
Skin	HS839T	5.7
Skin	HS852T	6.5
Skin	HS895T	5.9
Skin	HS934T	5.8
Skin	HS936T	6.1
Skin	HS939T	6.3
Skin	HS940T	6.2
Skin	HS944T	6
Skin	HT144	6.3
Skin	IGR1	6.1
Skin	IGR37	6.1
Skin	IGR39	6.2
Skin	IPC298	6.3
Skin	K029AX	6.3
Skin	LOXIMVI	6.6
Skin	MALME3M	6
Skin	MDAMB435S	5.8
Skin	MELHO	6.4
Skin	MELJUSO	6.3
Skin	MEWO	6.2
Skin	RPMI7951	5.9
Skin	RVH421	6
Skin	SH4	6.2
Skin	SKMEL1	6.2
Skin	SKMEL24	6
Skin	SKMEL28	6.3
Skin	SKMEL2	6.2
Skin	SKMEL30	5.9
Skin	SKMEL31	6.1
Skin	SKMEL3	6.6
Skin	SKMEL5	6.6
Skin	UACC257	5.9
Skin	UACC62	6.5
Skin	WM115	6.1
Skin	WM1799	6
Skin	WM2664	6.1
Skin	WM793	6.3
Skin	WM88	5.9
Skin	WM983B	5.8
Small intestine	HUTU80	6.6
Soft tissue	A204	6.1
Soft tissue	G401	6.4
Soft tissue	G402	6.2
Soft tissue	GCT	6.4
Soft tissue	HS729	5.9
Soft tissue	HT1080	6.4
Soft tissue	KYM1	6.9
Soft tissue	MESSA	6.2
Soft tissue	RD	6.3
Soft tissue	RH30	6.7
Soft tissue	RH41	6.9
Soft tissue	RKN	6.3
Soft tissue	S117	6.3
Soft tissue	SJRH30	6.3
Soft tissue	SKLMS1	6
Soft tissue	SKUT1	6.2
Soft tissue	TE125T	5.8
Soft tissue	TE159T	6
Soft tissue	TE441T	6.6
Soft tissue	TE617T	6.4
Stomach	2313287	6.6
Stomach	AGS	6.3
Stomach	AZ521	6.8
Stomach	ECC10	6.5
Stomach	ECC12	6.7
Stomach	FU97	6.4
Stomach	GCIY	6.2
Stomach	GSS	6.5
Stomach	GSU	6.5
Stomach	HGC27	6.1
Stomach	HS746T	6.1
Stomach	HUG1N	6.4
Stomach	IM95	6.5
Stomach	KATOIII	6.1
Stomach	KE39	6.5
Stomach	LMSU	6.3
Stomach	MKN1	6.3
Stomach	MKN45	6.6
Stomach	MKN74	6.4
Stomach	MKN7	6.2
Stomach	NCCSTCK140	6.6
Stomach	NCIN87	6.4
Stomach	NUGC2	6.6
Stomach	NUGC3	6.4
Stomach	NUGC4	6.5
Stomach	OCUM1	6.4
Stomach	RERFGC1B	6.4
Stomach	SH10TC	6.3
Stomach	SNU16	6.5
Stomach	SNU1	6.4
Stomach	SNU216	6.7
Stomach	SNU520	6.3
Stomach	SNU5	6.3
Stomach	SNU601	6.6
Stomach	SNU620	6.1
Stomach	SNU668	6.5
Stomach	SNU719	6.6
Stomach	TGBC11TKB	7
Thyroid	8305C	6
Thyroid	8505C	6.2
Thyroid	BCPAP	6.9
Thyroid	BHT101	6.5
Thyroid	CAL62	6.4
Thyroid	CGTHW1	5.7
Thyroid	FTC133	6
Thyroid	FTC238	5.9
Thyroid	ML1	6.6
Thyroid	SW579	6.1
Thyroid	TT2609C02	6.4
Thyroid	TT	6.7
Upper aerodigestive tract	BHY	6.8
Upper aerodigestive tract	BICR16	6.8
Upper aerodigestive tract	BICR18	6.7
Upper aerodigestive tract	BICR22	7
Upper aerodigestive tract	BICR31	6.1
Upper aerodigestive tract	BICR56	7.3
Upper aerodigestive tract	BICR6	6.9
Upper aerodigestive tract	CAL27	6.9
Upper aerodigestive tract	CAL33	7.1
Upper aerodigestive tract	DETROIT562	6.6
Upper aerodigestive tract	FADU	6.6
Upper aerodigestive tract	HS840T	6.1
Upper aerodigestive tract	HSC2	6.4
Upper aerodigestive tract	HSC3	6.2
Upper aerodigestive tract	HSC4	6.3
Upper aerodigestive tract	PECAPJ15	6.5
Upper aerodigestive tract	PECAPJ34CLONEC12	6.5
Upper aerodigestive tract	PECAPJ41CLONED2	6.5
Upper aerodigestive tract	PECAPJ49	6.4
Upper aerodigestive tract	SCC15	6.5
Upper aerodigestive tract	SCC25	6.7
Upper aerodigestive tract	SCC4	6.6
Upper aerodigestive tract	SCC9	6.7
Upper aerodigestive tract	SNU1076	6.5
Upper aerodigestive tract	SNU1214	6.4
Upper aerodigestive tract	SNU46	6.4
Upper aerodigestive tract	SNU899	6.7
Upper aerodigestive tract	YD10B	7.3
Upper aerodigestive tract	YD38	6.8
Upper aerodigestive tract	YD8	6.5
Urinary tract	5637	6.3
Urinary tract	639V	6.5
Urinary tract	647V	6.6
Urinary tract	BC3C	6.2
Urinary tract	BFTC905	6.7
Urinary tract	CAL29	6.7
Urinary tract	HS172T	6.1
Urinary tract	HT1197	6
Urinary tract	HT1376	6.5
Urinary tract	J82	6.1
Urinary tract	JMSU1	6.6
Urinary tract	KMBC2	6.3
Urinary tract	KU1919	6.9
Urinary tract	RT11284	6.2
Urinary tract	RT112	6.3
Urinary tract	RT4	6.1
Urinary tract	SCABER	6.7
Urinary tract	SW1710	6.6
Urinary tract	SW780	6.6
Urinary tract	T24	6.1
Urinary tract	TCCSUP	5.9
Urinary tract	UMUC1	6.8
Urinary tract	UMUC3	6.2
Urinary tract	VMCUB1	7.1

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	26.6
Adrenal gland	29.6
Appendix	42.1
Bone marrow	41.8
Breast	24.4
Cerebral cortex	24.8
Cervix, uterine	26.1
Colon	27.1
Duodenum	26.2
Endometrium	39.2
Epididymis	27
Esophagus	27.4
Fallopian tube	39.5
Gallbladder	32.7
Heart muscle	12
Kidney	20
Liver	7
Lung	42
Lymph node	40.3
Ovary	45.2
Pancreas	6.5
Parathyroid gland	63.1
Placenta	50.7
Prostate	30
Rectum	29.9
Salivary gland	9.5
Seminal vesicle	29.1
Skeletal muscle	8.3
Skin	33.9
Small intestine	30.4
Smooth muscle	34.1
Spleen	50.3
Stomach	24.7
Testis	82.6
Thyroid gland	41.3
Tonsil	29.9
Urinary bladder	30.5

> Text Mining based Expression

[ TOP ]

PMID	Expression	Cancer	Evidence
19779621	Overexpression	Chronic Lymphocytic Leukemia	These targets included 2 genes (BAZ2A and RNF41) that were significantly up-regulated (p<0.05) and 3 genes (RASSF5, MKK3 and LRIG1) that were significantly down-regulated (p<0.05) in CLL patients with down-regulated MIR-15a/16-1 expression.
25485837	Overexpression	Prostate Carcinoma	Here we show that the gene encoding BAZ2A (TIP5), a factor previously implicated in epigenetic rRNA gene silencing, is overexpressed in prostate cancer and is paradoxically involved in maintaining prostate cancer cell growth, a feature specific to cancer cells.

Summary
Symbol	BAZ2A
Name	bromodomain adjacent to zinc finger domain 2A
Aliases	KIAA0314; TIP5; WALp3; TTF-I interacting peptide 5; TTF-I-interacting protein 5; transcription termination f ......
Location	12q13.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.433	6.78e-20	17.1	61.6	21.3	Neutral
BRCA	Breast invasive carcinoma	1075	0.498	2.41e-68	13.2	66.8	20	Neutral
CESC	Cervical and endocervical cancers	292	0.315	3.65e-08	5.5	77.4	17.1	Neutral
COAD	Colon adenocarcinoma	449	0.341	1.02e-13	10.2	68.6	21.2	Neutral
ESCA	Esophageal carcinoma	183	0.395	3.01e-08	21.3	56.8	21.9	Neutral
GBM	Glioblastoma multiforme	147	0.163	0.0485	10.2	78.2	11.6	Neutral
HNSC	Head and Neck squamous cell carcinoma	514	0.345	8.32e-16	8.8	74.5	16.7	Neutral
KIRC	Kidney renal clear cell carcinoma	525	0.245	1.23e-08	0.8	76.4	22.9	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	0.345	1.84e-09	0	60.8	39.2	Gain
LAML	Acute Myeloid Leukemia	166	0.092	0.238	0.6	99.4	0	Neutral
LGG	Brain Lower Grade Glioma	513	0.205	2.95e-06	12.1	84.6	3.3	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.404	1.06e-15	9.9	76.1	14	Neutral
LUAD	Lung adenocarcinoma	512	0.515	5.56e-36	16	52.9	31.1	Neutral
LUSC	Lung squamous cell carcinoma	498	0.339	7.56e-15	10.8	58.2	30.9	Neutral
OV	Ovarian serous cystadenocarcinoma	300	0.587	3.9e-29	15.3	47.3	37.3	Gain
PAAD	Pancreatic adenocarcinoma	177	0.545	4.21e-15	13.6	70.1	16.4	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	0.404	9.56e-08	0	90.7	9.3	Neutral
PRAD	Prostate adenocarcinoma	491	0.163	0.000281	4.1	91.2	4.7	Neutral
READ	Rectum adenocarcinoma	164	0.333	1.3e-05	12.2	73.8	14	Neutral
SARC	Sarcoma	255	0.551	1.09e-21	27.1	58.4	14.5	Neutral
SKCM	Skin Cutaneous Melanoma	367	0.53	5.15e-28	19.3	67.6	13.1	Neutral
STAD	Stomach adenocarcinoma	413	0.375	3.18e-15	9.9	68.3	21.8	Neutral
TGCT	Testicular Germ Cell Tumors	150	0.227	0.00524	0	37.3	62.7	Gain
THCA	Thyroid carcinoma	497	0.157	0.000451	0	97	3	Neutral
THYM	Thymoma	119	0.135	0.144	5.9	90.8	3.4	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.289	9.27e-12	6.1	79.7	14.2	Neutral

Summary
Symbol	BAZ2A
Name	bromodomain adjacent to zinc finger domain 2A
Aliases	KIAA0314; TIP5; WALp3; TTF-I interacting peptide 5; TTF-I-interacting protein 5; transcription termination f ......
Location	12q13.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

[ TOP ]

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.153	0.00161	17	408	0.002	0.0203	NS/NA
BRCA	Breast invasive carcinoma	-0.115	0.000675	83	785	-0.001	0.0608	NS/NA
CESC	Cervical and endocervical cancers	-0.108	0.0576	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.161	0.00421	19	297	0.001	0.0187	NS/NA
ESCA	Esophageal carcinoma	-0.158	0.0281	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.155	0.218	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	0.006	0.894	20	522	0.001	0.0239	NS/NA
KIRC	Kidney renal clear cell carcinoma	-0.043	0.429	24	319	-0.001	0.535	NS/NA
KIRP	Kidney renal papillary cell carcinoma	-0.25	1.36e-05	23	275	-0.002	0.539	NS/NA
LAML	Acute Myeloid Leukemia	0	0.999	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	-0.055	0.208	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.058	0.237	41	373	-0.009	0.000491	NS/NA
LUAD	Lung adenocarcinoma	0.017	0.717	21	456	-0.004	0.693	NS/NA
LUSC	Lung squamous cell carcinoma	0.013	0.805	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	0.017	0.982	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.052	0.482	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	0.021	0.78	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.089	0.0396	35	498	-0.001	0.842	NS/NA
READ	Rectum adenocarcinoma	-0.183	0.067	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.18	0.0034	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.154	0.000793	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.095	0.0668	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.347	1.01e-05	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.035	0.407	50	509	-0.003	0.0154	NS/NA
THYM	Thymoma	-0.315	0.000429	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.058	0.209	34	431	-0.001	0.0324	NS/NA

Summary
Symbol	BAZ2A
Name	bromodomain adjacent to zinc finger domain 2A
Aliases	KIAA0314; TIP5; WALp3; TTF-I interacting peptide 5; TTF-I-interacting protein 5; transcription termination f ......
Location	12q13.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA) [ TOP ]
There is no antibody staining data.

Summary
Symbol	BAZ2A
Name	bromodomain adjacent to zinc finger domain 2A
Aliases	KIAA0314; TIP5; WALp3; TTF-I interacting peptide 5; TTF-I-interacting protein 5; transcription termination f ......
Location	12q13.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.45	NS	24476821
BRCA	Breast invasive carcinoma	521	1.83e-23	Significant	23000897
COAD	Colon adenocarcinoma	149	0.266	NS	22810696
GBM	Glioblastoma multiforme	157	0.0119	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	0.288	NS	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.113	NS	26536169
LGG	Brain Lower Grade Glioma	513	3.7e-13	Significant	26824661
LUAD	Lung adenocarcinoma	230	0.00968	Significant	25079552
LUSC	Lung squamous cell carcinoma	178	0.0738	NS	22960745
OV	Ovarian serous cystadenocarcinoma	287	0.11	NS	21720365
PRAD	Prostate adenocarcinoma	333	1.2e-07	Significant	26544944
READ	Rectum adenocarcinoma	67	0.493	NS	22810696
SKCM	Skin Cutaneous Melanoma	315	0.00939	Significant	26091043
STAD	Stomach adenocarcinoma	277	0.00147	Significant	25079317
THCA	Thyroid carcinoma	391	6.51e-08	Significant	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	2.29e-07	Significant	23636398

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	0.942	0.768	NS
BRCA	Breast invasive carcinoma	1079	1.285	0.283	NS
CESC	Cervical and endocervical cancers	291	3.332	0.002	Shorter
COAD	Colon adenocarcinoma	439	1.718	0.0761	NS
ESCA	Esophageal carcinoma	184	0.949	0.876	NS
GBM	Glioblastoma multiforme	158	0.931	0.776	NS
HNSC	Head and Neck squamous cell carcinoma	518	1.117	0.557	NS
KIRC	Kidney renal clear cell carcinoma	531	0.966	0.863	NS
KIRP	Kidney renal papillary cell carcinoma	287	1.499	0.317	NS
LAML	Acute Myeloid Leukemia	149	1.117	0.704	NS
LGG	Brain Lower Grade Glioma	511	0.86	0.592	NS
LIHC	Liver hepatocellular carcinoma	365	1.411	0.143	NS
LUAD	Lung adenocarcinoma	502	1.168	0.468	NS
LUSC	Lung squamous cell carcinoma	494	1.008	0.97	NS
OV	Ovarian serous cystadenocarcinoma	303	1.368	0.141	NS
PAAD	Pancreatic adenocarcinoma	177	1.256	0.433	NS
PCPG	Pheochromocytoma and Paraganglioma	179	643764001.532	0.142	NS
PRAD	Prostate adenocarcinoma	497	4.172	0.229	NS
READ	Rectum adenocarcinoma	159	1.217	0.757	NS
SARC	Sarcoma	259	0.922	0.765	NS
SKCM	Skin Cutaneous Melanoma	459	1.156	0.465	NS
STAD	Stomach adenocarcinoma	388	0.843	0.471	NS
TGCT	Testicular Germ Cell Tumors	134	1.184	0.905	NS
THCA	Thyroid carcinoma	500	0.426	0.311	NS
THYM	Thymoma	119	0.253	0.0844	NS
UCEC	Uterine Corpus Endometrial Carcinoma	543	1.271	0.427	NS

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	-0.083	0.0942	NS
BRCA	Breast invasive carcinoma	1071	0.039	0.197	NS
CESC	Cervical and endocervical cancers	167	0.006	0.94	NS
COAD	Colon adenocarcinoma	445	0.019	0.688	NS
ESCA	Esophageal carcinoma	162	-0.036	0.647	NS
HNSC	Head and Neck squamous cell carcinoma	448	-0.003	0.947	NS
KIRC	Kidney renal clear cell carcinoma	531	-0.04	0.363	NS
KIRP	Kidney renal papillary cell carcinoma	260	0.098	0.113	NS
LIHC	Liver hepatocellular carcinoma	347	0.105	0.0505	NS
LUAD	Lung adenocarcinoma	507	0.091	0.0395	Higher
LUSC	Lung squamous cell carcinoma	497	0.08	0.073	NS
OV	Ovarian serous cystadenocarcinoma	302	0.018	0.752	NS
PAAD	Pancreatic adenocarcinoma	176	-0.055	0.467	NS
READ	Rectum adenocarcinoma	156	0.017	0.836	NS
SKCM	Skin Cutaneous Melanoma	410	-0.029	0.563	NS
STAD	Stomach adenocarcinoma	392	0.102	0.0446	Higher
TGCT	Testicular Germ Cell Tumors	81	-0.249	0.0251	Lower
THCA	Thyroid carcinoma	499	0.001	0.978	NS
UCEC	Uterine Corpus Endometrial Carcinoma	501	0.129	0.00394	Higher

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	-0.06	0.328	NS
HNSC	Head and Neck squamous cell carcinoma	498	-0.061	0.175	NS
KIRC	Kidney renal clear cell carcinoma	525	-0.054	0.217	NS
LGG	Brain Lower Grade Glioma	514	-0.017	0.703	NS
LIHC	Liver hepatocellular carcinoma	366	0.221	2.05e-05	Higher
OV	Ovarian serous cystadenocarcinoma	296	0.103	0.0768	NS
PAAD	Pancreatic adenocarcinoma	176	0.015	0.848	NS
STAD	Stomach adenocarcinoma	406	-0.032	0.524	NS
UCEC	Uterine Corpus Endometrial Carcinoma	534	0.331	4.33e-15	Higher

Summary
Symbol	BAZ2A
Name	bromodomain adjacent to zinc finger domain 2A
Aliases	KIAA0314; TIP5; WALp3; TTF-I interacting peptide 5; TTF-I-interacting protein 5; transcription termination f ......
Location	12q13.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	BAZ2A
Name	bromodomain adjacent to zinc finger domain 2A
Aliases	KIAA0314; TIP5; WALp3; TTF-I interacting peptide 5; TTF-I-interacting protein 5; transcription termination f ......
Location	12q13.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for BAZ2A.

Summary
Symbol	BAZ2A
Name	bromodomain adjacent to zinc finger domain 2A
Aliases	KIAA0314; TIP5; WALp3; TTF-I interacting peptide 5; TTF-I-interacting protein 5; transcription termination f ......
Location	12q13.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining

[ TOP ]

PMID	Cancer	Hierarchy	Gene	Relation to CR	Evidence
25485837	Prostate Carcinoma	partner	EZH2	Binding	BAZ2A regulates numerous protein-coding genes and directly interacts with EZH2 to maintain epigenetic silencing at genes repressed in metastasis.