CR2Cancer

Summary
Symbol	BRD7
Name	bromodomain containing 7
Aliases	CELTIX1; bromodomain-containing 7; NAG4; 75 kDa bromodomain protein; protein CELTIX-1; Bromodomain-containin ......
Location	16q12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

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Domain

PF00439 Bromodomain
PF12024 Domain of unknown function (DUF3512)

Function

Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at 'Tyr-216'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at 'Lys-9' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at 'Lys-382', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase.

Classification

Class	Modification	Substrate	Product	PubMed
Histone modification read	#	H3K9ac, H3K14ac, H3K8ac	#	17498659

> Gene Ontology [ TOP ]
Biological Process	GO:0000082 G1/S transition of mitotic cell cycle GO:0006473 protein acetylation GO:0006475 internal protein amino acid acetylation GO:0007346 regulation of mitotic cell cycle GO:0010948 negative regulation of cell cycle process GO:0016055 Wnt signaling pathway GO:0016570 histone modification GO:0016573 histone acetylation GO:0018205 peptidyl-lysine modification GO:0018393 internal peptidyl-lysine acetylation GO:0018394 peptidyl-lysine acetylation GO:0031056 regulation of histone modification GO:0031058 positive regulation of histone modification GO:0035065 regulation of histone acetylation GO:0035066 positive regulation of histone acetylation GO:0043543 protein acylation GO:0044770 cell cycle phase transition GO:0044772 mitotic cell cycle phase transition GO:0044843 cell cycle G1/S phase transition GO:0045786 negative regulation of cell cycle GO:0045930 negative regulation of mitotic cell cycle GO:0072331 signal transduction by p53 class mediator GO:0198738 cell-cell signaling by wnt GO:1901796 regulation of signal transduction by p53 class mediator GO:1901983 regulation of protein acetylation GO:1901985 positive regulation of protein acetylation GO:1901987 regulation of cell cycle phase transition GO:1901988 negative regulation of cell cycle phase transition GO:1901990 regulation of mitotic cell cycle phase transition GO:1901991 negative regulation of mitotic cell cycle phase transition GO:1902275 regulation of chromatin organization GO:1902806 regulation of cell cycle G1/S phase transition GO:1902807 negative regulation of cell cycle G1/S phase transition GO:1905269 positive regulation of chromatin organization GO:2000045 regulation of G1/S transition of mitotic cell cycle GO:2000134 negative regulation of G1/S transition of mitotic cell cycle GO:2000756 regulation of peptidyl-lysine acetylation GO:2000758 positive regulation of peptidyl-lysine acetylation
Molecular Function	GO:0002039 p53 binding GO:0003713 transcription coactivator activity GO:0003714 transcription corepressor activity GO:0008134 transcription factor binding GO:0042393 histone binding GO:0070577 lysine-acetylated histone binding
Cellular Component	GO:0070603 SWI/SNF superfamily-type complex GO:0090544 BAF-type complex

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	R-HSA-74160: Gene Expression R-HSA-212436: Generic Transcription Pathway R-HSA-5633007: Regulation of TP53 Activity R-HSA-6804758: Regulation of TP53 Activity through Acetylation R-HSA-3700989: Transcriptional Regulation by TP53

Summary
Symbol	BRD7
Name	bromodomain containing 7
Aliases	CELTIX1; bromodomain-containing 7; NAG4; 75 kDa bromodomain protein; protein CELTIX-1; Bromodomain-containin ......
Location	16q12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM1609384	c.1346delT	p.L449fs*19	Deletion - Frameshift	Liver
COSM1378186	c.1710G>A	p.P570P	Substitution - coding silent	Stomach
COSM1478912	c.1869C>A	p.V623V	Substitution - coding silent	Breast
COSM4061081	c.1341G>A	p.E447E	Substitution - coding silent	Stomach
COSM4822863	c.1893G>C	p.L631F	Substitution - Missense	Cervix
COSM3741938	c.1444-4A>G	p.?	Unknown	Liver
COSM1609383	c.1757-1_1768delGCTGAACAAGTGA	p.?	Unknown	Liver
COSM4602101	c.632A>G	p.N211S	Substitution - Missense	Upper_aerodigestive_tract
COSM5612595	c.447-2A>G	p.?	Unknown	Adrenal_gland
COSM1609385	c.751C>G	p.Q251E	Substitution - Missense	Liver
COSM4803887	c.106G>T	p.E36*	Substitution - Nonsense	Liver
COSM5039006	c.385G>T	p.E129*	Substitution - Nonsense	Liver
COSM3737134	c.1368delG	p.Y457fs*11	Deletion - Frameshift	Soft_tissue
COSM703549	c.349C>T	p.P117S	Substitution - Missense	Lung
COSM349198	c.963C>T	p.I321I	Substitution - coding silent	Lung
COSM365078	c.151G>T	p.D51Y	Substitution - Missense	Lung
COSM3720984	c.846C>T	p.A282A	Substitution - coding silent	Upper_aerodigestive_tract
COSM1184900	c.398A>G	p.Q133R	Substitution - Missense	Large_intestine
COSM6002138	c.1370A>G	p.Y457C	Substitution - Missense	Prostate
COSM1723867	c.1859C>T	p.P620L	Substitution - Missense	Skin
COSM5054916	c.1900G>T	p.D634Y	Substitution - Missense	Stomach
COSM190399	c.1834C>T	p.R612*	Substitution - Nonsense	Endometrium
COSM1709150	c.108A>T	p.E36D	Substitution - Missense	Skin
COSM1709149	c.712C>T	p.Q238*	Substitution - Nonsense	Skin
COSM3510036	c.1339G>T	p.E447*	Substitution - Nonsense	Skin
COSM971266	c.830_831delAG	p.E277fs*18	Deletion - Frameshift	Central_nervous_system
COSM318943	c.258G>T	p.K86N	Substitution - Missense	Lung
COSM1378186	c.1710G>A	p.P570P	Substitution - coding silent	Large_intestine
COSM1629913	c.1365T>G	p.Y455*	Substitution - Nonsense	Liver
COSM5424819	c.190A>G	p.K64E	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM971262	c.1585G>A	p.V529I	Substitution - Missense	Endometrium
COSM3720984	c.846C>T	p.A282A	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM4642022	c.1922C>T	p.T641M	Substitution - Missense	Large_intestine
COSM703550	c.1381G>C	p.D461H	Substitution - Missense	Lung
COSM1290530	c.1019T>C	p.F340S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1749638	c.745G>C	p.D249H	Substitution - Missense	Urinary_tract
COSM4850923	c.1185A>C	p.K395N	Substitution - Missense	Cervix
COSM3510034	c.1709C>T	p.P570L	Substitution - Missense	Skin
COSM471791	c.19A>G	p.K7E	Substitution - Missense	Kidney
COSM3716945	c.274C>T	p.R92*	Substitution - Nonsense	Liver
COSM3510041	c.424C>T	p.Q142*	Substitution - Nonsense	Skin
COSM5770888	c.1339G>A	p.E447K	Substitution - Missense	Breast
COSM2834167	c.493G>A	p.A165T	Substitution - Missense	Large_intestine
COSM971268	c.526A>G	p.M176V	Substitution - Missense	Endometrium
COSM3716945	c.274C>T	p.R92*	Substitution - Nonsense	Liver
COSM5816839	c.895A>T	p.K299*	Substitution - Nonsense	Liver
COSM971264	c.877G>T	p.E293*	Substitution - Nonsense	Endometrium
COSM4944762	c.1365T>A	p.Y455*	Substitution - Nonsense	Liver
COSM4572528	c.774T>G	p.D258E	Substitution - Missense	Skin
COSM971266	c.830_831delAG	p.E277fs*18	Deletion - Frameshift	Urinary_tract
COSM2834138	c.1366C>T	p.P456S	Substitution - Missense	Large_intestine
COSM971266	c.830_831delAG	p.E277fs*18	Deletion - Frameshift	Endometrium
COSM5094768	c.1395_1405del11	p.D465fs*17	Deletion - Frameshift	Thymus
COSM1609385	c.751C>G	p.Q251E	Substitution - Missense	Liver
COSM3510039	c.637C>T	p.P213S	Substitution - Missense	Skin
COSM1184901	c.286C>T	p.R96W	Substitution - Missense	Large_intestine
COSM190399	c.1834C>T	p.R612*	Substitution - Nonsense	Cervix
COSM3510038	c.869C>T	p.P290L	Substitution - Missense	Skin
COSM1378192	c.591+1G>A	p.?	Unknown	Large_intestine
COSM971267	c.565G>T	p.D189Y	Substitution - Missense	Endometrium
COSM3679914	c.846C>G	p.A282A	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM1749639	c.130C>A	p.H44N	Substitution - Missense	Urinary_tract
COSM5384951	c.1853C>T	p.S618F	Substitution - Missense	Skin
COSM5504203	c.1677C>A	p.A559A	Substitution - coding silent	Biliary_tract
COSM5680537	c.794G>C	p.S265T	Substitution - Missense	Soft_tissue
COSM4061085	c.403C>T	p.P135S	Substitution - Missense	Stomach
COSM190403	c.994C>T	p.R332W	Substitution - Missense	Large_intestine
COSM971261	c.1909G>T	p.E637*	Substitution - Nonsense	Endometrium
COSM2834158	c.718C>G	p.L240V	Substitution - Missense	Bone
COSM3818061	c.1334T>G	p.I445S	Substitution - Missense	Breast
COSM1378189	c.1015G>A	p.E339K	Substitution - Missense	Large_intestine
COSM190399	c.1834C>T	p.R612*	Substitution - Nonsense	Large_intestine
COSM3794897	c.1273G>A	p.D425N	Substitution - Missense	Urinary_tract
COSM4061080	c.1370A>T	p.Y457F	Substitution - Missense	Stomach
COSM1378185	c.1867G>A	p.V623I	Substitution - Missense	Large_intestine
COSM5905311	c.1367C>T	p.P456L	Substitution - Missense	Skin
COSM3957626	c.1843A>G	p.M615V	Substitution - Missense	Lung
COSM1128939	c.703-1G>T	p.?	Unknown	Prostate
COSM3361793	c.680C>T	p.S227L	Substitution - Missense	Kidney
COSM334034	c.406C>T	p.L136F	Substitution - Missense	Lung
COSM3361792	c.1534T>C	p.S512P	Substitution - Missense	Kidney
COSM4666121	c.1407A>C	p.K469N	Substitution - Missense	Large_intestine
COSM390099	c.122G>T	p.S41I	Substitution - Missense	Lung
COSM435353	c.1381G>A	p.D461N	Substitution - Missense	Breast
COSM271831	c.399G>C	p.Q133H	Substitution - Missense	Large_intestine
COSM3818062	c.682G>C	p.G228R	Substitution - Missense	Breast
COSM1749639	c.130C>A	p.H44N	Substitution - Missense	Urinary_tract
COSM4499320	c.539C>T	p.T180I	Substitution - Missense	Skin
COSM2834145	c.941_942delAG	p.E314fs*5	Deletion - Frameshift	Large_intestine
COSM1184901	c.286C>T	p.R96W	Substitution - Missense	Stomach
COSM3510042	c.280C>T	p.R94*	Substitution - Nonsense	Skin
COSM3510037	c.1076C>T	p.P359L	Substitution - Missense	Skin
COSM4666120	c.1531G>T	p.D511Y	Substitution - Missense	Large_intestine
COSM3818064	c.325G>T	p.A109S	Substitution - Missense	Breast
COSM416982	c.561C>T	p.N187N	Substitution - coding silent	Urinary_tract
COSM471790	c.1340A>G	p.E447G	Substitution - Missense	Kidney
COSM5962083	c.789A>G	p.S263S	Substitution - coding silent	Breast
COSM1302009	c.1603G>C	p.D535H	Substitution - Missense	Urinary_tract
COSM4968239	c.1419C>T	p.S473S	Substitution - coding silent	Adrenal_gland
COSM4666122	c.856G>A	p.A286T	Substitution - Missense	Large_intestine
COSM4461126	c.1193C>T	p.P398L	Substitution - Missense	Skin
COSM3888603	c.329C>T	p.P110L	Substitution - Missense	Skin
COSM971266	c.830_831delAG	p.E277fs*18	Deletion - Frameshift	Large_intestine
COSM1378193	c.325G>A	p.A109T	Substitution - Missense	Large_intestine
COSM6016184	c.1047G>A	p.T349T	Substitution - coding silent	Skin
COSM4138112	c.1536C>T	p.S512S	Substitution - coding silent	Pancreas
COSM1629913	c.1365T>G	p.Y455*	Substitution - Nonsense	Prostate
COSM6002022	c.49G>T	p.E17*	Substitution - Nonsense	Prostate
COSM1609384	c.1346delT	p.L449fs*19	Deletion - Frameshift	Liver
COSM5809790	c.634A>T	p.K212*	Substitution - Nonsense	Liver
COSM2834132	c.1560G>T	p.A520A	Substitution - coding silent	Large_intestine
COSM3387465	c.1012-1G>C	p.?	Unknown	Pancreas
COSM212800	c.1352C>A	p.T451K	Substitution - Missense	Breast
COSM1378187	c.1656G>A	p.L552L	Substitution - coding silent	Large_intestine
COSM4061082	c.1046C>T	p.T349M	Substitution - Missense	Stomach
COSM3510035	c.1400T>G	p.L467*	Substitution - Nonsense	Skin
COSM1176754	c.1652G>A	p.R551K	Substitution - Missense	Endometrium
COSM5424819	c.190A>G	p.K64E	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM416981	c.506C>G	p.S169C	Substitution - Missense	Urinary_tract
COSM3421024	c.1923G>A	p.T641T	Substitution - coding silent	Large_intestine
COSM2834150	c.850G>A	p.A284T	Substitution - Missense	Large_intestine
COSM5619842	c.1397T>G	p.V466G	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM190399	c.1834C>T	p.R612*	Substitution - Nonsense	Large_intestine
COSM4061079	c.1526G>A	p.R509H	Substitution - Missense	Stomach
COSM4061084	c.447-1G>T	p.?	Unknown	Stomach
COSM4918010	c.1388T>A	p.L463*	Substitution - Nonsense	Liver
COSM5569988	c.1352C>T	p.T451M	Substitution - Missense	Prostate
COSM971263	c.892G>C	p.D298H	Substitution - Missense	Endometrium
COSM4061078	c.1563G>T	p.L521L	Substitution - coding silent	Stomach
COSM3510040	c.575C>T	p.S192F	Substitution - Missense	Skin
COSM4803887	c.106G>T	p.E36*	Substitution - Nonsense	Liver
COSM971265	c.831_832insAG	p.D278fs*35	Insertion - Frameshift	Endometrium
COSM4805311	c.1371T>G	p.Y457*	Substitution - Nonsense	Liver
COSM1629913	c.1365T>G	p.Y455*	Substitution - Nonsense	Liver
COSM1723867	c.1859C>T	p.P620L	Substitution - Missense	Skin
COSM1378190	c.831_832insAGAG	p.D278fs*19	Insertion - Frameshift	Large_intestine
COSM243231	c.199A>G	p.K67E	Substitution - Missense	Prostate
COSM6016185	c.1025G>C	p.R342T	Substitution - Missense	Skin
COSM1378194	c.260A>G	p.E87G	Substitution - Missense	Large_intestine
COSM1195639	c.1487C>T	p.A496V	Substitution - Missense	Lung
COSM1629915	c.470C>G	p.S157*	Substitution - Nonsense	Liver
COSM2834152	c.830A>G	p.E277G	Substitution - Missense	Biliary_tract
COSM971266	c.830_831delAG	p.E277fs*18	Deletion - Frameshift	Stomach
COSM1378184	c.1873G>A	p.E625K	Substitution - Missense	Large_intestine
COSM971266	c.830_831delAG	p.E277fs*18	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM3510043	c.147C>T	p.F49F	Substitution - coding silent	Skin
COSM4805311	c.1371T>G	p.Y457*	Substitution - Nonsense	Liver
COSM5363657	c.1539T>C	p.S513S	Substitution - coding silent	Large_intestine
COSM236064	c.1424C>T	p.T475I	Substitution - Missense	Autonomic_ganglia

> Text Mining based Variations [ TOP ]
There is no record for BRD7.

Summary
Symbol	BRD7
Name	bromodomain containing 7
Aliases	CELTIX1; bromodomain-containing 7; NAG4; 75 kDa bromodomain protein; protein CELTIX-1; Bromodomain-containin ......
Location	16q12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

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Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant
Q9NPI1	289	S	Phosphoserine	-	No	None detected
Q9NPI1	328	K	N6-acetyllysine	-	No	None detected
Q9NPI1	380	S	Phosphoserine	-	No	None detected
Q9NPI1	482	S	Phosphoserine	-	No	None detected
Q9NPI1	514	T	Phosphothreonine	-	No	None detected
Q9NPI1	621	S	Phosphoserine	-	No	None detected

Summary
Symbol	BRD7
Name	bromodomain containing 7
Aliases	CELTIX1; bromodomain-containing 7; NAG4; 75 kDa bromodomain protein; protein CELTIX-1; Bromodomain-containin ......
Location	16q12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

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Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	5.825	5.996	0.162	0.15	NS
BRCA	Breast invasive carcinoma	112	1100	5.926	5.809	-0.081	0.116	NS
CESC	Cervical and endocervical cancers	3	306	5.927	6.162	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	5.608	5.992	0.288	0.00812	NS
ESCA	Esophageal carcinoma	11	185	5.499	5.563	0.094	0.661	NS
GBM	Glioblastoma multiforme	5	166	5.517	5.513	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	5.559	5.469	-0.094	0.219	NS
KIRC	Kidney renal clear cell carcinoma	72	534	5.927	5.597	-0.304	2.37e-15	NS
KIRP	Kidney renal papillary cell carcinoma	32	291	5.681	5.84	0.119	0.122	NS
LAML	Acute Myeloid Leukemia	0	173	NA	6.059	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	6.369	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	4.705	4.876	0.132	0.136	NS
LUAD	Lung adenocarcinoma	59	517	5.766	5.787	0.024	0.708	NS
LUSC	Lung squamous cell carcinoma	51	501	5.688	5.928	0.236	0.00156	NS
OV	Ovarian serous cystadenocarcinoma	0	307	NA	5.39	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	5.573	5.693	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	5.74	5.852	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	5.681	5.723	0.027	0.606	NS
READ	Rectum adenocarcinoma	10	167	5.754	6.029	0.153	0.573	NS
SARC	Sarcoma	2	263	5.498	5.037	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	5.937	5.659	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	5.499	5.484	0	0.999	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	6.256	NA	NA	NA
THCA	Thyroid carcinoma	59	509	5.885	6.057	0.149	4.38e-08	NS
THYM	Thymoma	2	120	6.134	6.224	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	5.863	5.812	0.003	0.979	NS

> Cancer Cell Line Encyclopedia (CCLE)

[ TOP ]

Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	8.8
Autonomic ganglia	CHP212	9.7
Autonomic ganglia	IMR32	9.5
Autonomic ganglia	KELLY	9.5
Autonomic ganglia	KPNRTBM1	9.1
Autonomic ganglia	KPNSI9S	8.4
Autonomic ganglia	KPNYN	9.2
Autonomic ganglia	MHHNB11	8.9
Autonomic ganglia	NB1	9.5
Autonomic ganglia	NH6	8.8
Autonomic ganglia	SHSY5Y	9.5
Autonomic ganglia	SIMA	9.5
Autonomic ganglia	SKNAS	9.2
Autonomic ganglia	SKNBE2	9
Autonomic ganglia	SKNDZ	9.9
Autonomic ganglia	SKNFI	9.5
Autonomic ganglia	SKNSH	8.9
Biliary tract	HUCCT1	8.3
Biliary tract	HUH28	8.5
Biliary tract	SNU1079	9.1
Biliary tract	SNU1196	9.5
Biliary tract	SNU245	9.7
Biliary tract	SNU308	10
Biliary tract	SNU478	9
Bone	143B	9.7
Bone	A673	9.3
Bone	CADOES1	9
Bone	CAL78	7.6
Bone	G292CLONEA141B1	9.7
Bone	HOS	8.9
Bone	HS706T	8.5
Bone	HS737T	8.3
Bone	HS819T	8.2
Bone	HS821T	8.6
Bone	HS822T	8.4
Bone	HS863T	8.8
Bone	HS870T	8.4
Bone	HS888T	8.9
Bone	MG63	8.4
Bone	MHHES1	9.7
Bone	OUMS27	8.7
Bone	RDES	9.9
Bone	SJSA1	9.3
Bone	SKES1	9.6
Bone	SKNMC	9
Bone	SW1353	9
Bone	T173	8.5
Bone	TC71	9
Bone	U2OS	9.6
Breast	AU565	9.5
Breast	BT20	9.6
Breast	BT474	9.4
Breast	BT483	9.4
Breast	BT549	9
Breast	CAL120	9
Breast	CAL148	8.8
Breast	CAL51	9.9
Breast	CAL851	8.3
Breast	CAMA1	3.1
Breast	DU4475	10.9
Breast	EFM192A	9.3
Breast	EFM19	8.5
Breast	EVSAT	9.1
Breast	HCC1143	8.9
Breast	HCC1187	9
Breast	HCC1395	9.6
Breast	HCC1419	8.7
Breast	HCC1428	9.8
Breast	HCC1500	9.4
Breast	HCC1569	8.6
Breast	HCC1599	8.7
Breast	HCC1806	9.1
Breast	HCC1937	10.4
Breast	HCC1954	9.4
Breast	HCC202	8.5
Breast	HCC2157	8.2
Breast	HCC2218	8.2
Breast	HCC38	9.6
Breast	HCC70	10.1
Breast	HDQP1	9.5
Breast	HMC18	9.2
Breast	HS274T	8.7
Breast	HS281T	8.7
Breast	HS343T	8.7
Breast	HS578T	8
Breast	HS606T	8.5
Breast	HS739T	8.3
Breast	HS742T	8.2
Breast	JIMT1	8.9
Breast	KPL1	8.4
Breast	MCF7	8.3
Breast	MDAMB134VI	7.8
Breast	MDAMB157	7.8
Breast	MDAMB175VII	8.8
Breast	MDAMB231	8.7
Breast	MDAMB361	8.7
Breast	MDAMB415	8.7
Breast	MDAMB436	8.6
Breast	MDAMB453	9.9
Breast	MDAMB468	10
Breast	SKBR3	9.3
Breast	T47D	8.4
Breast	UACC812	8.1
Breast	UACC893	10.2
Breast	YMB1	8.9
Breast	ZR751	8.6
Breast	ZR7530	9.7
Central nervous system	1321N1	8.9
Central nervous system	42MGBA	8.4
Central nervous system	8MGBA	9
Central nervous system	A172	9.2
Central nervous system	AM38	9.1
Central nervous system	BECKER	9.2
Central nervous system	CAS1	8.7
Central nervous system	CCFSTTG1	9.1
Central nervous system	D283MED	10
Central nervous system	D341MED	9.1
Central nervous system	DAOY	8.8
Central nervous system	DBTRG05MG	8.8
Central nervous system	DKMG	8.5
Central nervous system	GAMG	8.9
Central nervous system	GB1	9.7
Central nervous system	GI1	8.8
Central nervous system	GMS10	9.1
Central nervous system	GOS3	9.2
Central nervous system	H4	9
Central nervous system	HS683	9.1
Central nervous system	KALS1	8.8
Central nervous system	KG1C	7.8
Central nervous system	KNS42	8.4
Central nervous system	KNS60	9
Central nervous system	KNS81	8.8
Central nervous system	KS1	9
Central nervous system	LN18	9.7
Central nervous system	LN229	9.1
Central nervous system	M059K	8.5
Central nervous system	MOGGCCM	8.9
Central nervous system	MOGGUVW	8.7
Central nervous system	NMCG1	8.8
Central nervous system	ONS76	9.1
Central nervous system	SF126	8.6
Central nervous system	SF295	9.5
Central nervous system	SNB19	10.5
Central nervous system	SNU1105	8.3
Central nervous system	SNU201	9
Central nervous system	SNU466	8.1
Central nervous system	SNU489	8.8
Central nervous system	SNU626	9
Central nervous system	SNU738	9.6
Central nervous system	SW1088	9.3
Central nervous system	SW1783	8.7
Central nervous system	T98G	9.2
Central nervous system	TM31	9.3
Central nervous system	U118MG	8.6
Central nervous system	U138MG	9.2
Central nervous system	U251MG	10
Central nervous system	U87MG	9.1
Central nervous system	YH13	9
Central nervous system	YKG1	9.2
Endometrium	AN3CA	9.5
Endometrium	COLO684	8.8
Endometrium	EFE184	8.6
Endometrium	EN	8.9
Endometrium	ESS1	9.1
Endometrium	HEC108	9.6
Endometrium	HEC151	9
Endometrium	HEC1A	9.3
Endometrium	HEC1B	9.3
Endometrium	HEC251	8.8
Endometrium	HEC265	6.9
Endometrium	HEC50B	9.5
Endometrium	HEC59	9.2
Endometrium	HEC6	9.5
Endometrium	ISHIKAWAHERAKLIO02ER	8.7
Endometrium	JHUEM1	9.6
Endometrium	JHUEM2	10.7
Endometrium	JHUEM3	8.9
Endometrium	KLE	8
Endometrium	MFE280	8.1
Endometrium	MFE296	9.5
Endometrium	MFE319	9.4
Endometrium	RL952	9.8
Endometrium	SNGM	9.8
Endometrium	SNU1077	8.4
Endometrium	SNU685	9
Endometrium	TEN	9.9
Haematopoietic and lymphoid	697	10.1
Haematopoietic and lymphoid	A3KAW	9.7
Haematopoietic and lymphoid	A4FUK	9.4
Haematopoietic and lymphoid	ALLSIL	10.1
Haematopoietic and lymphoid	AML193	9.6
Haematopoietic and lymphoid	AMO1	9.2
Haematopoietic and lymphoid	BCP1	9.5
Haematopoietic and lymphoid	BDCM	9.5
Haematopoietic and lymphoid	BL41	9.8
Haematopoietic and lymphoid	BL70	10
Haematopoietic and lymphoid	BV173	9.4
Haematopoietic and lymphoid	CA46	9.6
Haematopoietic and lymphoid	CI1	9.6
Haematopoietic and lymphoid	CMK115	9.2
Haematopoietic and lymphoid	CMK86	9.8
Haematopoietic and lymphoid	CMK	9.6
Haematopoietic and lymphoid	CMLT1	9.7
Haematopoietic and lymphoid	COLO775	9.9
Haematopoietic and lymphoid	DAUDI	10
Haematopoietic and lymphoid	DB	9.4
Haematopoietic and lymphoid	DEL	9
Haematopoietic and lymphoid	DND41	9.2
Haematopoietic and lymphoid	DOHH2	9.6
Haematopoietic and lymphoid	EB1	9.7
Haematopoietic and lymphoid	EB2	9
Haematopoietic and lymphoid	EHEB	9
Haematopoietic and lymphoid	EJM	9.2
Haematopoietic and lymphoid	EM2	9.3
Haematopoietic and lymphoid	EOL1	9.2
Haematopoietic and lymphoid	F36P	9.9
Haematopoietic and lymphoid	GA10	9.8
Haematopoietic and lymphoid	GDM1	8.2
Haematopoietic and lymphoid	GRANTA519	9.4
Haematopoietic and lymphoid	HDLM2	8.6
Haematopoietic and lymphoid	HDMYZ	9.2
Haematopoietic and lymphoid	HEL9217	9.2
Haematopoietic and lymphoid	HEL	9
Haematopoietic and lymphoid	HH	9.7
Haematopoietic and lymphoid	HL60	9.9
Haematopoietic and lymphoid	HPBALL	9.1
Haematopoietic and lymphoid	HS604T	8.5
Haematopoietic and lymphoid	HS611T	9.5
Haematopoietic and lymphoid	HS616T	8.5
Haematopoietic and lymphoid	HS751T	8.5
Haematopoietic and lymphoid	HT	9.8
Haematopoietic and lymphoid	HTK	9.6
Haematopoietic and lymphoid	HUNS1	9.1
Haematopoietic and lymphoid	HUT102	9
Haematopoietic and lymphoid	HUT78	9.1
Haematopoietic and lymphoid	JEKO1	9.9
Haematopoietic and lymphoid	JK1	9.2
Haematopoietic and lymphoid	JM1	9.8
Haematopoietic and lymphoid	JURKAT	10
Haematopoietic and lymphoid	JURLMK1	9.6
Haematopoietic and lymphoid	JVM2	9.1
Haematopoietic and lymphoid	JVM3	9.6
Haematopoietic and lymphoid	K562	9.8
Haematopoietic and lymphoid	KARPAS299	9.8
Haematopoietic and lymphoid	KARPAS422	9.4
Haematopoietic and lymphoid	KARPAS620	10.4
Haematopoietic and lymphoid	KASUMI1	9.5
Haematopoietic and lymphoid	KASUMI2	9.5
Haematopoietic and lymphoid	KASUMI6	9.2
Haematopoietic and lymphoid	KCL22	9.8
Haematopoietic and lymphoid	KE37	9.5
Haematopoietic and lymphoid	KE97	9.5
Haematopoietic and lymphoid	KG1	9.8
Haematopoietic and lymphoid	KHM1B	8.4
Haematopoietic and lymphoid	KIJK	8.4
Haematopoietic and lymphoid	KMH2	7.9
Haematopoietic and lymphoid	KMM1	9.5
Haematopoietic and lymphoid	KMS11	9.2
Haematopoietic and lymphoid	KMS12BM	9
Haematopoietic and lymphoid	KMS18	9.5
Haematopoietic and lymphoid	KMS20	8.5
Haematopoietic and lymphoid	KMS21BM	8.2
Haematopoietic and lymphoid	KMS26	8.9
Haematopoietic and lymphoid	KMS27	9.2
Haematopoietic and lymphoid	KMS28BM	8.9
Haematopoietic and lymphoid	KMS34	9.1
Haematopoietic and lymphoid	KO52	9.6
Haematopoietic and lymphoid	KOPN8	9.8
Haematopoietic and lymphoid	KU812	9.4
Haematopoietic and lymphoid	KYO1	9.4
Haematopoietic and lymphoid	L1236	10.6
Haematopoietic and lymphoid	L363	8.8
Haematopoietic and lymphoid	L428	9.2
Haematopoietic and lymphoid	L540	9.8
Haematopoietic and lymphoid	LAMA84	9.4
Haematopoietic and lymphoid	LOUCY	10.1
Haematopoietic and lymphoid	LP1	9.5
Haematopoietic and lymphoid	M07E	9.8
Haematopoietic and lymphoid	MC116	9.6
Haematopoietic and lymphoid	ME1	9
Haematopoietic and lymphoid	MEC1	9.7
Haematopoietic and lymphoid	MEC2	9.4
Haematopoietic and lymphoid	MEG01	9
Haematopoietic and lymphoid	MHHCALL2	9.8
Haematopoietic and lymphoid	MHHCALL3	9.6
Haematopoietic and lymphoid	MHHCALL4	9.8
Haematopoietic and lymphoid	MINO	9.6
Haematopoietic and lymphoid	MJ	10.4
Haematopoietic and lymphoid	MM1S	9.3
Haematopoietic and lymphoid	MOLM13	9.4
Haematopoietic and lymphoid	MOLM16	9.3
Haematopoietic and lymphoid	MOLM6	8.6
Haematopoietic and lymphoid	MOLP2	8.9
Haematopoietic and lymphoid	MOLP8	8.8
Haematopoietic and lymphoid	MOLT13	9.9
Haematopoietic and lymphoid	MOLT16	9.8
Haematopoietic and lymphoid	MOLT4	10.1
Haematopoietic and lymphoid	MONOMAC1	9.4
Haematopoietic and lymphoid	MONOMAC6	8.9
Haematopoietic and lymphoid	MOTN1	9.2
Haematopoietic and lymphoid	MUTZ5	9.5
Haematopoietic and lymphoid	MV411	9.4
Haematopoietic and lymphoid	NALM19	9.8
Haematopoietic and lymphoid	NALM1	9.6
Haematopoietic and lymphoid	NALM6	9.5
Haematopoietic and lymphoid	NAMALWA	10
Haematopoietic and lymphoid	NB4	10.2
Haematopoietic and lymphoid	NCIH929	8.6
Haematopoietic and lymphoid	NCO2	8.7
Haematopoietic and lymphoid	NOMO1	9.5
Haematopoietic and lymphoid	NUDHL1	8.5
Haematopoietic and lymphoid	NUDUL1	9.5
Haematopoietic and lymphoid	OCIAML2	9.2
Haematopoietic and lymphoid	OCIAML3	8.8
Haematopoietic and lymphoid	OCIAML5	9.3
Haematopoietic and lymphoid	OCILY10	9.8
Haematopoietic and lymphoid	OCILY19	9.4
Haematopoietic and lymphoid	OCILY3	9.7
Haematopoietic and lymphoid	OCIM1	9
Haematopoietic and lymphoid	OPM2	9.4
Haematopoietic and lymphoid	P12ICHIKAWA	10
Haematopoietic and lymphoid	P31FUJ	8.9
Haematopoietic and lymphoid	P3HR1	9.4
Haematopoietic and lymphoid	PCM6	8.8
Haematopoietic and lymphoid	PEER	9.9
Haematopoietic and lymphoid	PF382	9.9
Haematopoietic and lymphoid	PFEIFFER	10.2
Haematopoietic and lymphoid	PL21	9.5
Haematopoietic and lymphoid	RAJI	9.6
Haematopoietic and lymphoid	RCHACV	9.7
Haematopoietic and lymphoid	REC1	9.7
Haematopoietic and lymphoid	REH	9.8
Haematopoietic and lymphoid	RI1	8.6
Haematopoietic and lymphoid	RL	9.4
Haematopoietic and lymphoid	RPMI8226	9.7
Haematopoietic and lymphoid	RPMI8402	10.1
Haematopoietic and lymphoid	RS411	9.9
Haematopoietic and lymphoid	SEM	9.6
Haematopoietic and lymphoid	SET2	9.5
Haematopoietic and lymphoid	SIGM5	9.4
Haematopoietic and lymphoid	SKM1	9.4
Haematopoietic and lymphoid	SKMM2	8.1
Haematopoietic and lymphoid	SR786	9.1
Haematopoietic and lymphoid	ST486	9.5
Haematopoietic and lymphoid	SUDHL10	9.4
Haematopoietic and lymphoid	SUDHL1	10.1
Haematopoietic and lymphoid	SUDHL4	9.3
Haematopoietic and lymphoid	SUDHL5	10.2
Haematopoietic and lymphoid	SUDHL6	10
Haematopoietic and lymphoid	SUDHL8	9.4
Haematopoietic and lymphoid	SUPB15	9.6
Haematopoietic and lymphoid	SUPHD1	9
Haematopoietic and lymphoid	SUPM2	8.5
Haematopoietic and lymphoid	SUPT11	10
Haematopoietic and lymphoid	SUPT1	9.9
Haematopoietic and lymphoid	TALL1	10.2
Haematopoietic and lymphoid	TF1	9.4
Haematopoietic and lymphoid	THP1	9.4
Haematopoietic and lymphoid	TO175T	8.7
Haematopoietic and lymphoid	TOLEDO	9.1
Haematopoietic and lymphoid	U266B1	5.5
Haematopoietic and lymphoid	U937	9.3
Haematopoietic and lymphoid	UT7	10.4
Haematopoietic and lymphoid	WSUDLCL2	9.9
Kidney	769P	9.1
Kidney	786O	9.3
Kidney	A498	9
Kidney	A704	8.1
Kidney	ACHN	9.7
Kidney	BFTC909	9.3
Kidney	CAKI1	9.1
Kidney	CAKI2	8.9
Kidney	CAL54	9.2
Kidney	KMRC1	8.6
Kidney	KMRC20	9
Kidney	KMRC2	8.9
Kidney	KMRC3	8.2
Kidney	OSRC2	8.8
Kidney	RCC10RGB	8.9
Kidney	SNU1272	7.9
Kidney	SNU349	8.3
Kidney	TUHR10TKB	8.3
Kidney	TUHR14TKB	8.7
Kidney	TUHR4TKB	8.3
Kidney	VMRCRCW	8.9
Kidney	VMRCRCZ	9.4
Large intestine	C2BBE1	9.9
Large intestine	CCK81	10
Large intestine	CL11	9.6
Large intestine	CL14	9.5
Large intestine	CL34	9.6
Large intestine	CL40	9.5
Large intestine	COLO205	9.3
Large intestine	COLO320	10.8
Large intestine	COLO678	9.7
Large intestine	CW2	9.2
Large intestine	DLD1	9.5
Large intestine	GP2D	9.7
Large intestine	HCC56	9.1
Large intestine	HCT116	9.7
Large intestine	HCT15	9.9
Large intestine	HS675T	8.5
Large intestine	HS698T	8.4
Large intestine	HT115	8.5
Large intestine	HT29	9.6
Large intestine	HT55	9.9
Large intestine	KM12	9.1
Large intestine	LOVO	9.2
Large intestine	LS1034	9.8
Large intestine	LS123	9.6
Large intestine	LS180	9.9
Large intestine	LS411N	9.7
Large intestine	LS513	9.3
Large intestine	MDST8	8.8
Large intestine	NCIH508	8.6
Large intestine	NCIH716	9.5
Large intestine	NCIH747	9.5
Large intestine	OUMS23	8.6
Large intestine	RCM1	9.3
Large intestine	RKO	9.1
Large intestine	SKCO1	9.4
Large intestine	SNU1040	9.2
Large intestine	SNU1197	8.7
Large intestine	SNU175	9.4
Large intestine	SNU283	9.4
Large intestine	SNU407	10
Large intestine	SNU503	9.9
Large intestine	SNU61	9.5
Large intestine	SNU81	8.1
Large intestine	SNUC1	9.6
Large intestine	SNUC2A	9.3
Large intestine	SNUC4	9.3
Large intestine	SNUC5	9.7
Large intestine	SW1116	8.4
Large intestine	SW1417	9.9
Large intestine	SW1463	9.4
Large intestine	SW403	9.9
Large intestine	SW480	9.2
Large intestine	SW48	9.8
Large intestine	SW620	11.3
Large intestine	SW837	9.7
Large intestine	SW948	8.9
Large intestine	T84	9.5
Liver	ALEXANDERCELLS	8.7
Liver	C3A	9.8
Liver	HEP3B217	8.7
Liver	HEPG2	10.1
Liver	HLE	10.1
Liver	HLF	9.3
Liver	HUH1	9
Liver	HUH6	9.9
Liver	HUH7	8.5
Liver	JHH1	9.4
Liver	JHH2	8.5
Liver	JHH4	9
Liver	JHH5	8.7
Liver	JHH6	8.4
Liver	JHH7	9.4
Liver	LI7	8.7
Liver	PLCPRF5	8.6
Liver	SKHEP1	8.8
Liver	SNU182	8.8
Liver	SNU387	9
Liver	SNU398	9.7
Liver	SNU423	9
Liver	SNU449	8.9
Liver	SNU475	9
Liver	SNU761	9
Liver	SNU878	4.5
Liver	SNU886	7.9
Lung	A549	9.2
Lung	ABC1	8.9
Lung	BEN	7.9
Lung	CAL12T	9.5
Lung	CALU1	8.8
Lung	CALU3	9.6
Lung	CALU6	9.2
Lung	CHAGOK1	9.5
Lung	COLO668	9.5
Lung	COLO699	9.3
Lung	CORL105	9.4
Lung	CORL23	9.5
Lung	CORL24	9.2
Lung	CORL279	9.1
Lung	CORL311	9.5
Lung	CORL47	9.5
Lung	CORL51	9.4
Lung	CORL88	10.3
Lung	CORL95	9.2
Lung	CPCN	9.8
Lung	DMS114	9.7
Lung	DMS153	9
Lung	DMS273	9.9
Lung	DMS454	9.4
Lung	DMS53	9
Lung	DMS79	8.4
Lung	DV90	8.6
Lung	EBC1	9.3
Lung	EPLC272H	8.9
Lung	HARA	10.1
Lung	HCC1171	9.3
Lung	HCC1195	8.3
Lung	HCC15	10.3
Lung	HCC2279	7.3
Lung	HCC2935	9.9
Lung	HCC33	10.1
Lung	HCC366	9.1
Lung	HCC4006	8.9
Lung	HCC44	8.9
Lung	HCC78	9.8
Lung	HCC827	9.2
Lung	HCC95	9.6
Lung	HLC1	9.2
Lung	HLFA	8.2
Lung	HS229T	8.8
Lung	HS618T	8.3
Lung	IALM	8.9
Lung	KNS62	8.8
Lung	LC1F	9.3
Lung	LC1SQSF	9.6
Lung	LCLC103H	9.8
Lung	LCLC97TM1	9.4
Lung	LK2	10.7
Lung	LOUNH91	9.6
Lung	LU65	8.9
Lung	LU99	8.6
Lung	LUDLU1	9.8
Lung	LXF289	8.9
Lung	MORCPR	9.8
Lung	NCIH1048	8.4
Lung	NCIH1092	10.5
Lung	NCIH1105	11.2
Lung	NCIH1155	9.7
Lung	NCIH1184	9.9
Lung	NCIH1299	9.3
Lung	NCIH1339	9.8
Lung	NCIH1341	8
Lung	NCIH1355	9
Lung	NCIH1373	8.5
Lung	NCIH1385	8.4
Lung	NCIH1395	9.1
Lung	NCIH1435	10.2
Lung	NCIH1436	10
Lung	NCIH1437	10
Lung	NCIH146	9.2
Lung	NCIH1563	8.7
Lung	NCIH1568	9.9
Lung	NCIH1573	9.4
Lung	NCIH1581	10.1
Lung	NCIH1618	9.9
Lung	NCIH1623	9.6
Lung	NCIH1648	8.9
Lung	NCIH1650	10.3
Lung	NCIH1651	9.2
Lung	NCIH1666	8.9
Lung	NCIH1693	8.4
Lung	NCIH1694	9.3
Lung	NCIH1703	9.1
Lung	NCIH1734	8.6
Lung	NCIH1755	9.4
Lung	NCIH1781	8.9
Lung	NCIH1792	8.7
Lung	NCIH1793	9.4
Lung	NCIH1836	10.2
Lung	NCIH1838	8.6
Lung	NCIH1869	8.9
Lung	NCIH1876	10.4
Lung	NCIH1915	7.6
Lung	NCIH1930	9.2
Lung	NCIH1944	9.3
Lung	NCIH1963	10.9
Lung	NCIH196	9.4
Lung	NCIH1975	9.1
Lung	NCIH2009	9.2
Lung	NCIH2023	9
Lung	NCIH2029	8.8
Lung	NCIH2030	10
Lung	NCIH2066	9.1
Lung	NCIH2081	8.9
Lung	NCIH2085	8.5
Lung	NCIH2087	8.6
Lung	NCIH209	10.2
Lung	NCIH2106	10.1
Lung	NCIH2110	9
Lung	NCIH211	10.1
Lung	NCIH2122	8.8
Lung	NCIH2126	9.2
Lung	NCIH2141	9.4
Lung	NCIH2170	9.8
Lung	NCIH2171	10
Lung	NCIH2172	9.4
Lung	NCIH2196	8.4
Lung	NCIH2227	8.9
Lung	NCIH2228	9.5
Lung	NCIH226	9.3
Lung	NCIH2286	9.8
Lung	NCIH2291	8.3
Lung	NCIH2342	9.3
Lung	NCIH2347	7.8
Lung	NCIH23	8.9
Lung	NCIH2405	9.5
Lung	NCIH2444	8.6
Lung	NCIH292	9.3
Lung	NCIH322	9.5
Lung	NCIH3255	9
Lung	NCIH358	9.5
Lung	NCIH441	9.5
Lung	NCIH446	8.6
Lung	NCIH460	9.7
Lung	NCIH510	10.1
Lung	NCIH520	12.3
Lung	NCIH522	8.9
Lung	NCIH524	10.1
Lung	NCIH526	9
Lung	NCIH596	8.4
Lung	NCIH647	8.9
Lung	NCIH650	9.5
Lung	NCIH661	9
Lung	NCIH69	8.9
Lung	NCIH727	9.5
Lung	NCIH810	9.1
Lung	NCIH82	10
Lung	NCIH838	9.8
Lung	NCIH841	9.2
Lung	NCIH854	8.9
Lung	NCIH889	9.8
Lung	PC14	9.2
Lung	RERFLCAD1	8.8
Lung	RERFLCAD2	9.1
Lung	RERFLCAI	9.4
Lung	RERFLCKJ	8.5
Lung	RERFLCMS	8.7
Lung	RERFLCSQ1	9.7
Lung	SBC5	9.7
Lung	SCLC21H	9.7
Lung	SHP77	9.5
Lung	SKLU1	9
Lung	SKMES1	8.9
Lung	SQ1	9.3
Lung	SW1271	8.9
Lung	SW1573	9.3
Lung	SW900	8.6
Lung	VMRCLCD	8.9
Lung	VMRCLCP	10.2
Oesophagus	COLO680N	9.5
Oesophagus	ECGI10	8.8
Oesophagus	KYSE140	9.6
Oesophagus	KYSE150	9.9
Oesophagus	KYSE180	9.7
Oesophagus	KYSE270	9
Oesophagus	KYSE30	9.1
Oesophagus	KYSE410	9.2
Oesophagus	KYSE450	9.7
Oesophagus	KYSE510	9.8
Oesophagus	KYSE520	10.4
Oesophagus	KYSE70	8.7
Oesophagus	OE19	9.1
Oesophagus	OE33	10
Oesophagus	TE10	10
Oesophagus	TE11	9.1
Oesophagus	TE14	9.4
Oesophagus	TE15	9.4
Oesophagus	TE1	8.7
Oesophagus	TE4	9.5
Oesophagus	TE5	9.5
Oesophagus	TE6	8.9
Oesophagus	TE8	9.1
Oesophagus	TE9	9.8
Oesophagus	TT	10.1
Ovary	59M	9.8
Ovary	A2780	9.7
Ovary	CAOV3	9
Ovary	CAOV4	8
Ovary	COLO704	8.8
Ovary	COV318	8.4
Ovary	COV362	9
Ovary	COV434	9.5
Ovary	COV504	8.9
Ovary	COV644	8.9
Ovary	EFO21	9.8
Ovary	EFO27	9.3
Ovary	ES2	9.3
Ovary	FUOV1	9.4
Ovary	HEYA8	9
Ovary	HS571T	8.7
Ovary	IGROV1	9.2
Ovary	JHOC5	9.7
Ovary	JHOM1	8.5
Ovary	JHOM2B	9.5
Ovary	JHOS2	9
Ovary	JHOS4	9
Ovary	KURAMOCHI	8.8
Ovary	MCAS	9.8
Ovary	NIHOVCAR3	8.5
Ovary	OAW28	9.8
Ovary	OAW42	8.6
Ovary	OC314	9.4
Ovary	OC316	9.2
Ovary	ONCODG1	8.6
Ovary	OV56	8.4
Ovary	OV7	8.2
Ovary	OV90	9.5
Ovary	OVCAR4	10.3
Ovary	OVCAR8	9.6
Ovary	OVISE	8.1
Ovary	OVK18	9.2
Ovary	OVKATE	9.1
Ovary	OVMANA	8.6
Ovary	OVSAHO	9
Ovary	OVTOKO	9.5
Ovary	RMGI	9.3
Ovary	RMUGS	9.2
Ovary	SKOV3	9.5
Ovary	SNU119	8.1
Ovary	SNU840	9.3
Ovary	SNU8	8.3
Ovary	TOV112D	9.8
Ovary	TOV21G	8.6
Ovary	TYKNU	9.6
Pancreas	ASPC1	8.7
Pancreas	BXPC3	9.3
Pancreas	CAPAN1	7.9
Pancreas	CAPAN2	9.8
Pancreas	CFPAC1	8.5
Pancreas	DANG	9.4
Pancreas	HPAC	7
Pancreas	HPAFII	9.2
Pancreas	HS766T	9.4
Pancreas	HUPT3	9.5
Pancreas	HUPT4	9.6
Pancreas	KCIMOH1	7.3
Pancreas	KLM1	9.9
Pancreas	KP2	10
Pancreas	KP3	9.2
Pancreas	KP4	9.6
Pancreas	L33	9.5
Pancreas	MIAPACA2	9.9
Pancreas	PANC0203	9.3
Pancreas	PANC0213	8.8
Pancreas	PANC0327	8.2
Pancreas	PANC0403	9.3
Pancreas	PANC0504	9.1
Pancreas	PANC0813	9
Pancreas	PANC1005	10.2
Pancreas	PANC1	8.6
Pancreas	PATU8902	9.6
Pancreas	PATU8988S	9.4
Pancreas	PATU8988T	10.4
Pancreas	PK1	9.5
Pancreas	PK45H	8.8
Pancreas	PK59	9.2
Pancreas	PL45	9.5
Pancreas	PSN1	9.3
Pancreas	QGP1	9.1
Pancreas	SNU213	8.4
Pancreas	SNU324	9.1
Pancreas	SNU410	8.8
Pancreas	SU8686	9.1
Pancreas	SUIT2	9.3
Pancreas	SW1990	9.3
Pancreas	T3M4	9.1
Pancreas	TCCPAN2	9.4
Pancreas	YAPC	9.7
Pleura	ACCMESO1	8.7
Pleura	DM3	8.3
Pleura	ISTMES1	9.2
Pleura	ISTMES2	9.2
Pleura	JL1	9
Pleura	MPP89	8.8
Pleura	MSTO211H	10.2
Pleura	NCIH2052	8.9
Pleura	NCIH2452	9.1
Pleura	NCIH28	8.8
Prostate	22RV1	8.7
Prostate	DU145	9.2
Prostate	LNCAPCLONEFGC	8.6
Prostate	MDAPCA2B	9.1
Prostate	NCIH660	8.3
Prostate	PC3	8.5
Prostate	VCAP	8.6
Salivary gland	A253	9
Salivary gland	YD15	8.8
Skin	A101D	8.3
Skin	A2058	9.5
Skin	A375	9.3
Skin	C32	8.8
Skin	CHL1	9.4
Skin	CJM	9.2
Skin	COLO679	8.4
Skin	COLO741	8.9
Skin	COLO783	8.8
Skin	COLO792	7.1
Skin	COLO800	8.9
Skin	COLO818	8.2
Skin	COLO829	8
Skin	COLO849	8.7
Skin	G361	8.2
Skin	GRM	9.1
Skin	HMCB	9.4
Skin	HS294T	8.5
Skin	HS600T	8.5
Skin	HS688AT	8.6
Skin	HS695T	9.1
Skin	HS839T	8.4
Skin	HS852T	9.8
Skin	HS895T	8.3
Skin	HS934T	8.9
Skin	HS936T	8.7
Skin	HS939T	8.6
Skin	HS940T	8.1
Skin	HS944T	8.4
Skin	HT144	8.8
Skin	IGR1	9.2
Skin	IGR37	9.1
Skin	IGR39	9.1
Skin	IPC298	8.9
Skin	K029AX	8.8
Skin	LOXIMVI	9.1
Skin	MALME3M	8
Skin	MDAMB435S	9
Skin	MELHO	8.4
Skin	MELJUSO	8.9
Skin	MEWO	9.7
Skin	RPMI7951	9.2
Skin	RVH421	8.5
Skin	SH4	8.6
Skin	SKMEL1	9.2
Skin	SKMEL24	8.9
Skin	SKMEL28	8.1
Skin	SKMEL2	8.9
Skin	SKMEL30	8.6
Skin	SKMEL31	8.9
Skin	SKMEL3	8.8
Skin	SKMEL5	8.7
Skin	UACC257	8.5
Skin	UACC62	8.6
Skin	WM115	8.6
Skin	WM1799	9.1
Skin	WM2664	9
Skin	WM793	8.7
Skin	WM88	9.6
Skin	WM983B	8.8
Small intestine	HUTU80	9.5
Soft tissue	A204	8.9
Soft tissue	G401	9.4
Soft tissue	G402	8.6
Soft tissue	GCT	8.9
Soft tissue	HS729	8.5
Soft tissue	HT1080	8.9
Soft tissue	KYM1	9.1
Soft tissue	MESSA	9.5
Soft tissue	RD	8.5
Soft tissue	RH30	9.3
Soft tissue	RH41	8.5
Soft tissue	RKN	9
Soft tissue	S117	10.1
Soft tissue	SJRH30	9.2
Soft tissue	SKLMS1	8.9
Soft tissue	SKUT1	8.2
Soft tissue	TE125T	8.4
Soft tissue	TE159T	8.9
Soft tissue	TE441T	9.4
Soft tissue	TE617T	9.5
Stomach	2313287	6.7
Stomach	AGS	9.1
Stomach	AZ521	9.5
Stomach	ECC10	10.4
Stomach	ECC12	9.7
Stomach	FU97	10
Stomach	GCIY	8.6
Stomach	GSS	11.6
Stomach	GSU	9.3
Stomach	HGC27	10.3
Stomach	HS746T	8.2
Stomach	HUG1N	8.5
Stomach	IM95	8.3
Stomach	KATOIII	9.7
Stomach	KE39	10
Stomach	LMSU	9.4
Stomach	MKN1	8
Stomach	MKN45	10
Stomach	MKN74	8.8
Stomach	MKN7	9.1
Stomach	NCCSTCK140	9.3
Stomach	NCIN87	10.5
Stomach	NUGC2	9.1
Stomach	NUGC3	6.3
Stomach	NUGC4	8.6
Stomach	OCUM1	9.6
Stomach	RERFGC1B	9.4
Stomach	SH10TC	8.6
Stomach	SNU16	9.3
Stomach	SNU1	9.4
Stomach	SNU216	9.6
Stomach	SNU520	9.4
Stomach	SNU5	9.3
Stomach	SNU601	9.7
Stomach	SNU620	9.3
Stomach	SNU668	9.9
Stomach	SNU719	10.6
Stomach	TGBC11TKB	10
Thyroid	8305C	9
Thyroid	8505C	9.6
Thyroid	BCPAP	8.2
Thyroid	BHT101	8.6
Thyroid	CAL62	9.6
Thyroid	CGTHW1	9.1
Thyroid	FTC133	9.2
Thyroid	FTC238	9.3
Thyroid	ML1	9.2
Thyroid	SW579	9
Thyroid	TT2609C02	9.2
Thyroid	TT	8.3
Upper aerodigestive tract	BHY	8.9
Upper aerodigestive tract	BICR16	7.8
Upper aerodigestive tract	BICR18	9.6
Upper aerodigestive tract	BICR22	8.8
Upper aerodigestive tract	BICR31	9
Upper aerodigestive tract	BICR56	8.6
Upper aerodigestive tract	BICR6	8.8
Upper aerodigestive tract	CAL27	9
Upper aerodigestive tract	CAL33	9.3
Upper aerodigestive tract	DETROIT562	8.9
Upper aerodigestive tract	FADU	10.2
Upper aerodigestive tract	HS840T	8.7
Upper aerodigestive tract	HSC2	8.4
Upper aerodigestive tract	HSC3	8.5
Upper aerodigestive tract	HSC4	9.3
Upper aerodigestive tract	PECAPJ15	9.5
Upper aerodigestive tract	PECAPJ34CLONEC12	9.4
Upper aerodigestive tract	PECAPJ41CLONED2	9.6
Upper aerodigestive tract	PECAPJ49	9.3
Upper aerodigestive tract	SCC15	8.4
Upper aerodigestive tract	SCC25	8.4
Upper aerodigestive tract	SCC4	8.8
Upper aerodigestive tract	SCC9	8.5
Upper aerodigestive tract	SNU1076	8.4
Upper aerodigestive tract	SNU1214	9.1
Upper aerodigestive tract	SNU46	8.6
Upper aerodigestive tract	SNU899	9.3
Upper aerodigestive tract	YD10B	8.9
Upper aerodigestive tract	YD38	9.5
Upper aerodigestive tract	YD8	9.5
Urinary tract	5637	8.2
Urinary tract	639V	9.7
Urinary tract	647V	9.4
Urinary tract	BC3C	10
Urinary tract	BFTC905	10.1
Urinary tract	CAL29	9.1
Urinary tract	HS172T	8.3
Urinary tract	HT1197	9
Urinary tract	HT1376	9.4
Urinary tract	J82	9.1
Urinary tract	JMSU1	9.4
Urinary tract	KMBC2	9.8
Urinary tract	KU1919	9.2
Urinary tract	RT11284	9.5
Urinary tract	RT112	9.1
Urinary tract	RT4	8.8
Urinary tract	SCABER	9.2
Urinary tract	SW1710	9
Urinary tract	SW780	9.2
Urinary tract	T24	9.4
Urinary tract	TCCSUP	10.2
Urinary tract	UMUC1	9.4
Urinary tract	UMUC3	9.4
Urinary tract	VMCUB1	8.9

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	35.4
Adrenal gland	44.1
Appendix	46.3
Bone marrow	40.8
Breast	44.8
Cerebral cortex	56.8
Cervix, uterine	45
Colon	35.9
Duodenum	32.1
Endometrium	61.3
Epididymis	56.6
Esophagus	47.2
Fallopian tube	55.4
Gallbladder	42.3
Heart muscle	23.6
Kidney	40.7
Liver	15.8
Lung	53.6
Lymph node	54.6
Ovary	41.1
Pancreas	8
Parathyroid gland	105.1
Placenta	62
Prostate	54.5
Rectum	43.9
Salivary gland	14.4
Seminal vesicle	46
Skeletal muscle	17.5
Skin	49.3
Small intestine	36.4
Smooth muscle	51
Spleen	48.6
Stomach	32.2
Testis	105.3
Thyroid gland	67.1
Tonsil	48.8
Urinary bladder	39.2

> Text Mining based Expression

[ TOP ]

PMID	Expression	Cancer	Evidence
27580131	Underexpression	Lung Adenocarcinoma	In this study, we showed that the expression of BRD7 was downregulated in lung adenocarcinoma tissues and cells. The lower of BRD7 levels in patients with lung adenocarcinoma was associated with shortened disease-free survival.
26919247	Underexpression	Hepatocellular Carcinoma	BRD7 was down-regulated in tumor tissues and HCC cell lines. Kaplan-Meier survival curves revealed higher survival rates in patients with higher BRD7 expression levels compared to those with lower BRD7 levels.
25743841	Underexpression (hypermethylation)	Oral Squamous Cell Carcinoma	The identification of BRD7 promoter hypermethylation in 74% of well differentiated oral squamous cell carcinomas indicates that the methylation dependent silencing of BRD7 gene is a frequent event in carcinogenesis.
24198243	Underexpression	Ovarian Carcinoma	The BRD7 expression was downregulated in the ovarian cancer tissues compared with normal (P < 0.05), high-grade serous cancer exhibited significantly decreased expression of BRD7 compared with low-grade (P < 0.01) serous cancer.
24840027	Underexpression	Human Osteosarcoma	Furthermore, there is a strong inverse correlation of protein levels between BRD7 and Cdh1 or Cdc20, and lower BRD7 expression is an indicator for poor prognosis in patients with osteosarcoma.
23215825	Underexpression	Colorectal Carcinoma	BRD7 was down-regulated in colorectal cancer cell lines and cancerous tissues compared with that in normal colon epithelial cells and adjacent noncancerous tissue samples.
22008115	Overexpression	Non-Small Cell Lung Cancer	BRD7 expression was significantly higher in cancer tissues than that in normal lung tissues. BRD7 is highly expressed in NSCLC.
18772500	Overexpression	Acute Leukemia	The mRNA relative expression of BRD7 in patients with AL was higher than that of the control group (P=0.001).

Summary
Symbol	BRD7
Name	bromodomain containing 7
Aliases	CELTIX1; bromodomain-containing 7; NAG4; 75 kDa bromodomain protein; protein CELTIX-1; Bromodomain-containin ......
Location	16q12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.62	2.76e-44	28.5	52.2	19.3	Neutral
BRCA	Breast invasive carcinoma	1075	0.758	4.37e-201	55.3	30.8	13.9	Loss
CESC	Cervical and endocervical cancers	292	0.675	2.94e-40	18.2	69.2	12.7	Neutral
COAD	Colon adenocarcinoma	449	0.269	7.34e-09	5.6	69.9	24.5	Neutral
ESCA	Esophageal carcinoma	183	0.549	8.18e-16	27.9	47	25.1	Neutral
GBM	Glioblastoma multiforme	147	0.595	1.96e-15	22.4	74.1	3.4	Neutral
HNSC	Head and Neck squamous cell carcinoma	514	0.664	1.31e-66	18.3	60.1	21.6	Neutral
KIRC	Kidney renal clear cell carcinoma	525	0.449	1.81e-27	4.2	77	18.9	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	0.534	1.25e-22	2.4	44.8	52.8	Gain
LAML	Acute Myeloid Leukemia	166	0.296	0.00011	1.8	98.2	0	Neutral
LGG	Brain Lower Grade Glioma	513	0.316	2.3e-13	4.1	92.6	3.3	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.63	1.37e-41	39	55.5	5.5	Loss
LUAD	Lung adenocarcinoma	512	0.611	1.27e-53	26.2	50.8	23	Neutral
LUSC	Lung squamous cell carcinoma	498	0.603	1.02e-50	36.7	44.6	18.7	Loss
OV	Ovarian serous cystadenocarcinoma	300	0.781	8.39e-63	60.3	30	9.7	Loss
PAAD	Pancreatic adenocarcinoma	177	0.422	4.89e-09	6.8	80.2	13	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	0.224	0.00416	3.7	92.6	3.7	Neutral
PRAD	Prostate adenocarcinoma	491	0.734	3.83e-84	21.4	76.2	2.4	Neutral
READ	Rectum adenocarcinoma	164	0.378	5.87e-07	7.9	67.1	25	Neutral
SARC	Sarcoma	255	0.597	5.76e-26	52.9	40.8	6.3	Loss
SKCM	Skin Cutaneous Melanoma	367	0.639	1.58e-43	32.7	56.1	11.2	Neutral
STAD	Stomach adenocarcinoma	413	0.503	7.12e-28	27.1	62.5	10.4	Neutral
TGCT	Testicular Germ Cell Tumors	150	0.493	1.52e-10	34.7	54	11.3	Loss
THCA	Thyroid carcinoma	497	0.282	1.57e-10	0.4	97	2.6	Neutral
THYM	Thymoma	119	0.718	4.24e-20	10.1	88.2	1.7	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.398	7.08e-22	23.6	72.4	3.9	Neutral

Summary
Symbol	BRD7
Name	bromodomain containing 7
Aliases	CELTIX1; bromodomain-containing 7; NAG4; 75 kDa bromodomain protein; protein CELTIX-1; Bromodomain-containin ......
Location	16q12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

[ TOP ]

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	0.063	0.192	17	408	-0.051	3.06e-11	NS/NA
BRCA	Breast invasive carcinoma	0.181	7.54e-08	83	785	0.002	0.266	NS/NA
CESC	Cervical and endocervical cancers	0.072	0.205	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	0.224	6.34e-05	19	297	-0.005	0.000296	NS/NA
ESCA	Esophageal carcinoma	0.214	0.00274	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.26	0.0371	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	0.001	0.973	20	522	-0.008	2.04e-06	NS/NA
KIRC	Kidney renal clear cell carcinoma	0.382	3.18e-13	24	319	-0.022	7.98e-11	NS/NA
KIRP	Kidney renal papillary cell carcinoma	0.107	0.0653	23	275	-0.018	0.125	NS/NA
LAML	Acute Myeloid Leukemia	-0.076	0.325	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	0.068	0.116	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	0.007	0.89	41	373	-0.051	2.9e-31	NS/NA
LUAD	Lung adenocarcinoma	0.002	0.973	21	456	-0.022	0.00567	NS/NA
LUSC	Lung squamous cell carcinoma	0.123	0.0167	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	0.483	0.194	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	0.047	0.524	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	0.137	0.0609	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	0.101	0.02	35	498	-0.019	1.89e-15	NS/NA
READ	Rectum adenocarcinoma	0.227	0.0224	2	99	NA	NA	NS/NA
SARC	Sarcoma	0.054	0.384	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	0.168	0.000259	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	0.043	0.408	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.092	0.253	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	0.066	0.116	50	509	-0.005	0.0049	NS/NA
THYM	Thymoma	0.281	0.00179	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	0.052	0.262	34	431	-0.006	0.000316	NS/NA

Summary
Symbol	BRD7
Name	bromodomain containing 7
Aliases	CELTIX1; bromodomain-containing 7; NAG4; 75 kDa bromodomain protein; protein CELTIX-1; Bromodomain-containin ......
Location	16q12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Level	Level Name
Adrenal gland	3	High
Appendix	3	High
Bone marrow	3	High
Breast	3	High
Bronchus	3	High
Caudate	2	Medium
Cerebellum	3	High
Cerebral cortex	2	Medium
Cervix, uterine	3	High
Colon	3	High
Duodenum	3	High
Endometrium	3	High
Epididymis	3	High
Esophagus	3	High
Fallopian tube	3	High
Gallbladder	3	High
Heart muscle	2	Medium
Hippocampus	1	Low
Kidney	3	High
Liver	2	Medium
Lung	3	High
Lymph node	3	High
Nasopharynx	3	High
Oral mucosa	3	High
Ovary	2	Medium
Pancreas	3	High
Parathyroid gland	3	High
Placenta	3	High
Prostate	3	High
Rectum	3	High
Salivary gland	3	High
Seminal vesicle	3	High
Skin	3	High
Small intestine	3	High
Smooth muscle	2	Medium
Soft tissue	3	High
Spleen	2	Medium
Stomach	3	High
Testis	3	High
Thyroid gland	3	High
Tonsil	3	High
Urinary bladder	3	High
Vagina	3	High

Summary
Symbol	BRD7
Name	bromodomain containing 7
Aliases	CELTIX1; bromodomain-containing 7; NAG4; 75 kDa bromodomain protein; protein CELTIX-1; Bromodomain-containin ......
Location	16q12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.385	NS	24476821
BRCA	Breast invasive carcinoma	521	1.34e-15	Significant	23000897
COAD	Colon adenocarcinoma	149	0.00369	Significant	22810696
GBM	Glioblastoma multiforme	157	0.000959	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	1.81e-05	Significant	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.228	NS	26536169
LGG	Brain Lower Grade Glioma	513	9.79e-18	Significant	26824661
LUAD	Lung adenocarcinoma	230	0.000307	Significant	25079552
LUSC	Lung squamous cell carcinoma	178	0.00326	Significant	22960745
OV	Ovarian serous cystadenocarcinoma	287	0.0148	Significant	21720365
PRAD	Prostate adenocarcinoma	333	0.000494	Significant	26544944
READ	Rectum adenocarcinoma	67	0.0143	Significant	22810696
SKCM	Skin Cutaneous Melanoma	315	0.315	NS	26091043
STAD	Stomach adenocarcinoma	277	0.00028	Significant	25079317
THCA	Thyroid carcinoma	391	0.183	NS	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	0.000399	Significant	23636398

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	1.23	0.332	NS
BRCA	Breast invasive carcinoma	1079	2.204	0.00435	Shorter
CESC	Cervical and endocervical cancers	291	0.765	0.502	NS
COAD	Colon adenocarcinoma	439	0.862	0.583	NS
ESCA	Esophageal carcinoma	184	1.795	0.0617	NS
GBM	Glioblastoma multiforme	158	0.805	0.378	NS
HNSC	Head and Neck squamous cell carcinoma	518	1.101	0.633	NS
KIRC	Kidney renal clear cell carcinoma	531	0.764	0.191	NS
KIRP	Kidney renal papillary cell carcinoma	287	0.767	0.478	NS
LAML	Acute Myeloid Leukemia	149	1.025	0.93	NS
LGG	Brain Lower Grade Glioma	511	0.375	0.000134	Longer
LIHC	Liver hepatocellular carcinoma	365	1.165	0.521	NS
LUAD	Lung adenocarcinoma	502	1.065	0.766	NS
LUSC	Lung squamous cell carcinoma	494	1.258	0.245	NS
OV	Ovarian serous cystadenocarcinoma	303	1.181	0.421	NS
PAAD	Pancreatic adenocarcinoma	177	1.396	0.264	NS
PCPG	Pheochromocytoma and Paraganglioma	179	2.713	0.368	NS
PRAD	Prostate adenocarcinoma	497	3.241	0.271	NS
READ	Rectum adenocarcinoma	159	0.63	0.431	NS
SARC	Sarcoma	259	0.772	0.367	NS
SKCM	Skin Cutaneous Melanoma	459	0.836	0.322	NS
STAD	Stomach adenocarcinoma	388	0.733	0.161	NS
TGCT	Testicular Germ Cell Tumors	134	555852430.795	0.172	NS
THCA	Thyroid carcinoma	500	0.134	0.0293	Longer
THYM	Thymoma	119	0	0.0299	Longer
UCEC	Uterine Corpus Endometrial Carcinoma	543	0.887	0.692	NS

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	0.001	0.979	NS
BRCA	Breast invasive carcinoma	1071	0.03	0.322	NS
CESC	Cervical and endocervical cancers	167	0.034	0.665	NS
COAD	Colon adenocarcinoma	445	0.088	0.0635	NS
ESCA	Esophageal carcinoma	162	0.011	0.893	NS
HNSC	Head and Neck squamous cell carcinoma	448	0.001	0.989	NS
KIRC	Kidney renal clear cell carcinoma	531	-0.07	0.108	NS
KIRP	Kidney renal papillary cell carcinoma	260	0.068	0.277	NS
LIHC	Liver hepatocellular carcinoma	347	0.077	0.154	NS
LUAD	Lung adenocarcinoma	507	0.048	0.276	NS
LUSC	Lung squamous cell carcinoma	497	0.045	0.314	NS
OV	Ovarian serous cystadenocarcinoma	302	0.01	0.859	NS
PAAD	Pancreatic adenocarcinoma	176	0.003	0.972	NS
READ	Rectum adenocarcinoma	156	0.118	0.141	NS
SKCM	Skin Cutaneous Melanoma	410	-0.048	0.329	NS
STAD	Stomach adenocarcinoma	392	-0.027	0.59	NS
TGCT	Testicular Germ Cell Tumors	81	0.134	0.235	NS
THCA	Thyroid carcinoma	499	0.031	0.484	NS
UCEC	Uterine Corpus Endometrial Carcinoma	501	-0.032	0.479	NS

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	0.064	0.291	NS
HNSC	Head and Neck squamous cell carcinoma	498	-0.159	0.000354	Lower
KIRC	Kidney renal clear cell carcinoma	525	-0.017	0.698	NS
LGG	Brain Lower Grade Glioma	514	-0.114	0.00952	Lower
LIHC	Liver hepatocellular carcinoma	366	-0.038	0.473	NS
OV	Ovarian serous cystadenocarcinoma	296	0.049	0.4	NS
PAAD	Pancreatic adenocarcinoma	176	0.108	0.152	NS
STAD	Stomach adenocarcinoma	406	0.024	0.635	NS
UCEC	Uterine Corpus Endometrial Carcinoma	534	0.047	0.282	NS

Summary
Symbol	BRD7
Name	bromodomain containing 7
Aliases	CELTIX1; bromodomain-containing 7; NAG4; 75 kDa bromodomain protein; protein CELTIX-1; Bromodomain-containin ......
Location	16q12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	BRD7
Name	bromodomain containing 7
Aliases	CELTIX1; bromodomain-containing 7; NAG4; 75 kDa bromodomain protein; protein CELTIX-1; Bromodomain-containin ......
Location	16q12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for BRD7.

Summary
Symbol	BRD7
Name	bromodomain containing 7
Aliases	CELTIX1; bromodomain-containing 7; NAG4; 75 kDa bromodomain protein; protein CELTIX-1; Bromodomain-containin ......
Location	16q12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining

[ TOP ]

PMID	Cancer	Hierarchy	Gene	Relation to CR	Evidence
24198243	Ovarian Carcinoma	downstream	β-catenin pathway	Negative regulation	BRD7 negatively regulated β-catenin pathway, resulting in decreased its accumulation in the nucleus.