Browse CHD2 in pancancer

Summary
SymbolCHD2
Namechromodomain helicase DNA binding protein 2
Aliases FLJ38614; DKFZp547I1315; DKFZp781D1727; DKFZp686E01200; EEOC; ATP-dependent helicase CHD2; CHD-2; Chromodoma ......
Location15q26.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Domain, Function and Classification
> Gene Ontology
> KEGG and Reactome Pathway
> Domain, Function and Classification
 
Domain PF00385 Chromo (CHRromatin Organisation MOdifier) domain
PF13907 Domain of unknown function (DUF4208)
PF00271 Helicase conserved C-terminal domain
PF00176 SNF2 family N-terminal domain
Function

DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3. Involved in myogenesis via interaction with MYOD1: binds to myogenic gene regulatory sequences and mediates incorporation of histone H3.3 prior to the onset of myogenic gene expression, promoting their expression (By similarity).

Classification
Class Modification Substrate Product PubMed
Chromatin remodelling # # # 12592387
> Gene Ontology
 
Biological Process GO:0002244 hematopoietic progenitor cell differentiation
GO:0007517 muscle organ development
GO:0032392 DNA geometric change
GO:0032508 DNA duplex unwinding
GO:0048863 stem cell differentiation
GO:0060218 hematopoietic stem cell differentiation
GO:0071103 DNA conformation change
Molecular Function GO:0001046 core promoter sequence-specific DNA binding
GO:0001047 core promoter binding
GO:0003678 DNA helicase activity
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0008026 ATP-dependent helicase activity
GO:0008094 DNA-dependent ATPase activity
GO:0016887 ATPase activity
GO:0042393 histone binding
GO:0042623 ATPase activity, coupled
GO:0070035 purine NTP-dependent helicase activity
Cellular Component -
> KEGG and Reactome Pathway
 
KEGG -
Reactome -
Summary
SymbolCHD2
Namechromodomain helicase DNA binding protein 2
Aliases FLJ38614; DKFZp547I1315; DKFZp781D1727; DKFZp686E01200; EEOC; ATP-dependent helicase CHD2; CHD-2; Chromodoma ......
Location15q26.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Mutation landscape in primary tumor tissue from TCGA
> Mutation landscape in cancer cell line from CCLE
> All mutations from COSMIC database V81
> Variations from text mining
> The Cancer Genome Atlas (TCGA)
 
> Cancer Cell Line Encyclopedia (CCLE)
 
There is no record.
> Catalogue of Somatic Mutations in Cancer (COSMIC)
 
COSMIC ID CDS change AA change Mutation Type Anatomical Site
COSM1608859c.2858A>Gp.N953SSubstitution - MissenseLiver
COSM4614305c.3725_3726delAAp.K1245fs*13Deletion - FrameshiftLarge_intestine
COSM4671964c.1680C>Tp.N560NSubstitution - coding silentLarge_intestine
COSM3706827c.3004G>Tp.A1002SSubstitution - MissenseLiver
COSM702077c.332G>Tp.R111LSubstitution - MissenseLung
COSM1608855c.1242A>Gp.L414LSubstitution - coding silentLiver
COSM1200954c.3662C>Tp.S1221FSubstitution - MissenseLarge_intestine
COSM966704c.1369G>Tp.E457*Substitution - NonsenseEndometrium
COSM5023449c.4951G>Ap.G1651SSubstitution - MissenseBone
COSM1301601c.4978G>Tp.D1660YSubstitution - MissenseUrinary_tract
COSM4818258c.735C>Tp.L245LSubstitution - coding silentUpper_aerodigestive_tract
COSM3817103c.2125C>Tp.L709FSubstitution - MissenseBreast
COSM5487294c.2597C>Gp.S866WSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM966708c.2602A>Cp.R868RSubstitution - coding silentEndometrium
COSM5557940c.936G>Cp.K312NSubstitution - MissenseProstate
COSM3706827c.3004G>Tp.A1002SSubstitution - MissenseLiver
COSM1323749c.2030A>Cp.D677ASubstitution - MissenseOvary
COSM4994618c.2299C>Gp.L767VSubstitution - MissenseLarge_intestine
COSM3726023c.2087T>Ap.F696YSubstitution - MissenseLung
COSM4578635c.1578G>Ap.L526LSubstitution - coding silentBone
COSM2141008c.5001G>Ap.Q1667QSubstitution - coding silentLarge_intestine
COSM966700c.1234G>Ap.E412KSubstitution - MissenseEndometrium
COSM5761259c.677C>Tp.A226VSubstitution - MissensePancreas
COSM1375552c.3725delAp.K1245fs*4Deletion - FrameshiftLarge_intestine
COSM1749384c.839C>Tp.S280FSubstitution - MissenseUrinary_tract
COSM5954891c.1248A>Gp.K416KSubstitution - coding silentUpper_aerodigestive_tract
COSM966716c.3851T>Gp.I1284SSubstitution - MissenseEndometrium
COSM232031c.4964C>Tp.P1655LSubstitution - MissenseSkin
COSM1608861c.3066+9A>Gp.?UnknownLiver
COSM1375552c.3725delAp.K1245fs*4Deletion - FrameshiftHaematopoietic_and_lymphoid_tissue
COSM416757c.4810C>Tp.Q1604*Substitution - NonsenseUrinary_tract
COSM3420726c.3042A>Gp.T1014TSubstitution - coding silentLarge_intestine
COSM1375534c.514_515insAp.V175fs*18Insertion - FrameshiftLarge_intestine
COSM5126807c.2842C>Tp.R948WSubstitution - MissenseLarge_intestine
COSM4058029c.3207G>Ap.M1069ISubstitution - MissenseStomach
COSM2140920c.3261T>Cp.S1087SSubstitution - coding silentLarge_intestine
COSM1665897c.3886-2A>Gp.?UnknownKidney
COSM434564c.1948C>Tp.Q650*Substitution - NonsenseBreast
COSM1375552c.3725delAp.K1245fs*4Deletion - FrameshiftStomach
COSM1200962c.2973+2T>Cp.?UnknownLarge_intestine
COSM3887814c.2539A>Tp.K847*Substitution - NonsenseSkin
COSM416755c.4819C>Tp.H1607YSubstitution - MissenseUrinary_tract
COSM5967271c.686_686delAp.N229fs*20Deletion - FrameshiftSalivary_gland
COSM1284107c.1063G>Ap.V355ISubstitution - MissenseAutonomic_ganglia
COSM3817101c.1696G>Ap.G566SSubstitution - MissenseBreast
COSM5573512c.63-1G>Ap.?UnknownProstate
COSM4474521c.1927C>Tp.L643LSubstitution - coding silentSkin
COSM1290465c.4279-1G>Ap.?UnknownHaematopoietic_and_lymphoid_tissue
COSM1290457c.1934C>Tp.T645MSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM5982179c.2524A>Gp.K842ESubstitution - MissenseUpper_aerodigestive_tract
COSM702073c.637G>Ap.D213NSubstitution - MissenseLung
COSM1756909c.2338C>Tp.Q780*Substitution - NonsenseUrinary_tract
COSM2140814c.202A>Cp.S68RSubstitution - MissenseLarge_intestine
COSM2140850c.1059G>Ap.G353GSubstitution - coding silentLarge_intestine
COSM5041393c.3052C>Gp.L1018VSubstitution - MissenseLiver
COSM1375536c.515delAp.V175fs*1Deletion - FrameshiftLarge_intestine
COSM966721c.4435G>Tp.V1479LSubstitution - MissenseEndometrium
COSM1478479c.3752G>Ap.R1251HSubstitution - MissenseBreast
COSM2140940c.3602G>Cp.G1201ASubstitution - MissenseOesophagus
COSM1375548c.3038C>Gp.A1013GSubstitution - MissenseLarge_intestine
COSM4058019c.1171T>Cp.S391PSubstitution - MissenseStomach
COSM4058037c.4352G>Ap.S1451NSubstitution - MissenseStomach
COSM4758868c.1478A>Tp.N493ISubstitution - MissenseStomach
COSM4671968c.2537G>Ap.R846QSubstitution - MissenseLarge_intestine
COSM4643940c.3803G>Ap.R1268HSubstitution - MissenseLarge_intestine
COSM1608863c.4835A>Gp.H1612RSubstitution - MissenseLiver
COSM5479022c.1008A>Cp.K336NSubstitution - MissenseLarge_intestine
COSM5028033c.2065C>Gp.L689VSubstitution - MissenseBreast
COSM4058035c.3830G>Ap.G1277DSubstitution - MissenseStomach
COSM396930c.467C>Gp.S156*Substitution - NonsenseLung
COSM1301595c.199G>Ap.E67KSubstitution - MissenseUrinary_tract
COSM4818671c.4793C>Gp.S1598*Substitution - NonsenseCervix
COSM5506486c.498_499delAGp.S168fs*1Deletion - FrameshiftBiliary_tract
COSM5743714c.422G>Ap.G141DSubstitution - MissenseSmall_intestine
COSM1129057c.2896G>Cp.E966QSubstitution - MissenseProstate
COSM5012941c.2095C>Tp.R699WSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM1708571c.916C>Tp.Q306*Substitution - NonsenseSkin
COSM4963938c.891C>Ap.D297ESubstitution - MissensePancreas
COSM3505527c.1827T>Cp.I609ISubstitution - coding silentSkin
COSM4058031c.3309T>Cp.S1103SSubstitution - coding silentStomach
COSM3988224c.497C>Tp.A166VSubstitution - MissenseKidney
COSM391248c.3724_3725insAp.Y1246fs*13Insertion - FrameshiftUpper_aerodigestive_tract
COSM5629821c.2660C>Tp.S887FSubstitution - MissenseOesophagus
COSM159975c.3059A>Tp.Q1020LSubstitution - MissenseBreast
COSM3944339c.3425C>Tp.A1142VSubstitution - MissenseOvary
COSM3730008c.682delAp.N229fs*20Deletion - FrameshiftStomach
COSM3505533c.2123C>Tp.S708FSubstitution - MissenseSkin
COSM2140924c.3286C>Ap.Q1096KSubstitution - MissenseLarge_intestine
COSM4058021c.1302A>Gp.G434GSubstitution - coding silentStomach
COSM146173c.4592+2T>Gp.?UnknownHaematopoietic_and_lymphoid_tissue
COSM3794540c.5154G>Ap.R1718RSubstitution - coding silentUrinary_tract
COSM4595565c.2168C>Tp.A723VSubstitution - MissenseUpper_aerodigestive_tract
COSM3505545c.4056G>Tp.V1352VSubstitution - coding silentSkin
COSM4614305c.3725_3726delAAp.K1245fs*13Deletion - FrameshiftLarge_intestine
COSM1749384c.839C>Tp.S280FSubstitution - MissenseUrinary_tract
COSM4408194c.4637G>Ap.R1546QSubstitution - MissensePancreas
COSM1375538c.670C>Tp.R224*Substitution - NonsenseLarge_intestine
COSM5045532c.11A>Gp.N4SSubstitution - MissenseOesophagus
COSM5946109c.?p.R550SSubstitution - MissensePituitary
COSM3505547c.4096C>Tp.P1366SSubstitution - MissenseSkin
COSM146266c.2094delCp.R699fs*35Deletion - FrameshiftHaematopoietic_and_lymphoid_tissue
COSM1375550c.3440G>Ap.G1147DSubstitution - MissenseLarge_intestine
COSM1301597c.4291G>Tp.D1431YSubstitution - MissenseUrinary_tract
COSM3794530c.2809C>Tp.H937YSubstitution - MissenseUrinary_tract
COSM966706c.1804G>Tp.D602YSubstitution - MissenseEndometrium
COSM3794538c.3756C>Gp.V1252VSubstitution - coding silentUrinary_tract
COSM4671958c.147T>Cp.H49HSubstitution - coding silentLarge_intestine
COSM1375536c.515delAp.V175fs*1Deletion - FrameshiftStomach
COSM4671966c.1862G>Ap.R621QSubstitution - MissenseLarge_intestine
COSM3794526c.859G>Cp.E287QSubstitution - MissenseUrinary_tract
COSM966688c.87G>Ap.S29SSubstitution - coding silentEndometrium
COSM5418983c.4231_4234delAAAGp.E1412fs*64Deletion - FrameshiftHaematopoietic_and_lymphoid_tissue
COSM434568c.3077T>Gp.F1026CSubstitution - MissenseBreast
COSM4981334c.1973C>Ap.S658YSubstitution - MissenseOesophagus
COSM3505543c.3409C>Tp.R1137*Substitution - NonsenseSkin
COSM3505549c.4396C>Ap.Q1466KSubstitution - MissenseSkin
COSM5940506c.4693-6C>Tp.?UnknownSkin
COSM434566c.2142A>Gp.E714ESubstitution - coding silentBreast
COSM966712c.3633G>Tp.K1211NSubstitution - MissenseEndometrium
COSM966710c.2741G>Ap.R914HSubstitution - MissenseEndometrium
COSM3505551c.4733C>Tp.P1578LSubstitution - MissenseSkin
COSM5740466c.2470G>Ap.A824TSubstitution - MissenseSmall_intestine
COSM5012941c.2095C>Tp.R699WSubstitution - MissenseKidney
COSM5967272c.?p.?UnknownSalivary_gland
COSM2140950c.3998G>Ap.G1333DSubstitution - MissenseLarge_intestine
COSM5802016c.4165_4166insAp.Q1392fs*17Insertion - FrameshiftBreast
COSM1248201c.2607T>Gp.A869ASubstitution - coding silentOesophagus
COSM3505535c.2356C>Ap.L786ISubstitution - MissenseSkin
COSM3817097c.362G>Ap.R121QSubstitution - MissenseBreast
COSM5031314c.1666G>Ap.A556TSubstitution - MissensePancreas
COSM1756911c.4459G>Ap.D1487NSubstitution - MissenseUrinary_tract
COSM966694c.594G>Ap.Q198QSubstitution - coding silentEndometrium
COSM5416069c.3797A>Tp.D1266VSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM1749386c.2142A>Tp.E714DSubstitution - MissenseUrinary_tract
COSM4656198c.4006G>Ap.E1336KSubstitution - MissenseLarge_intestine
COSM5727281c.276G>Ap.R92RSubstitution - coding silentSkin
COSM3505518c.41C>Tp.S14LSubstitution - MissenseSkin
COSM702065c.4358C>Gp.P1453RSubstitution - MissenseLung
COSM4671974c.3332A>Tp.D1111VSubstitution - MissenseLarge_intestine
COSM3387160c.3004G>Ap.A1002TSubstitution - MissensePancreas
COSM1375544c.2356C>Tp.L786FSubstitution - MissenseLarge_intestine
COSM1194606c.4197G>Tp.E1399DSubstitution - MissenseLung
COSM69426c.1810-1G>Cp.?UnknownOvary
COSM702071c.1797C>Gp.L599LSubstitution - coding silentLung
COSM3420728c.3751C>Tp.R1251CSubstitution - MissenseLarge_intestine
COSM702081c.87G>Tp.S29SSubstitution - coding silentLung
COSM5913656c.2129C>Tp.P710LSubstitution - MissenseSkin
COSM3361600c.4188G>Ap.E1396ESubstitution - coding silentKidney
COSM5047173c.4313C>Gp.S1438*Substitution - NonsenseOesophagus
COSM1248203c.1188A>Gp.T396TSubstitution - coding silentStomach
COSM4058015c.649G>Ap.A217TSubstitution - MissenseStomach
COSM2141006c.4980C>Tp.D1660DSubstitution - coding silentLarge_intestine
COSM966698c.1039G>Ap.E347KSubstitution - MissenseEndometrium
COSM4671970c.2733T>Cp.N911NSubstitution - coding silentLarge_intestine
COSM4849467c.2376G>Ap.K792KSubstitution - coding silentCervix
COSM2140812c.192G>Ap.S64SSubstitution - coding silentProstate
COSM3377741c.2995T>Cp.L999LSubstitution - coding silentPancreas
COSM380893c.4034G>Ap.R1345QSubstitution - MissenseLung
COSM3887812c.1955C>Tp.S652FSubstitution - MissenseSkin
COSM146173c.4592+2T>Gp.?UnknownHaematopoietic_and_lymphoid_tissue
COSM5961401c.2668A>Gp.N890DSubstitution - MissenseAdrenal_gland
COSM1375554c.4381_4383delGATp.D1463delDDeletion - In frameLarge_intestine
COSM5048461c.3214C>Gp.R1072GSubstitution - MissenseOesophagus
COSM1197054c.1823G>Ap.S608NSubstitution - MissenseLung
COSM4450761c.826+1G>Ap.?UnknownSkin
COSM4963938c.891C>Ap.D297ESubstitution - MissensePancreas
COSM4910543c.2753A>Gp.K918RSubstitution - MissenseLiver
COSM2140858c.1397G>Ap.R466QSubstitution - MissenseLarge_intestine
COSM1608853c.1202A>Gp.H401RSubstitution - MissenseLiver
COSM4522406c.1161G>Ap.K387KSubstitution - coding silentSkin
COSM1301599c.4769C>Gp.S1590CSubstitution - MissenseUrinary_tract
COSM4777670c.4173_4174insAp.Q1392fs*17Insertion - FrameshiftProstate
COSM2140994c.4841C>Tp.P1614LSubstitution - MissenseSkin
COSM5035778c.2577G>Tp.E859DSubstitution - MissenseOesophagus
COSM3387158c.827-8T>Gp.?UnknownPancreas
COSM3505537c.2410C>Tp.R804*Substitution - NonsenseSkin
COSM4777670c.4173_4174insAp.Q1392fs*17Insertion - FrameshiftProstate
COSM3794536c.3741C>Gp.C1247WSubstitution - MissenseUrinary_tract
COSM4058033c.3360G>Ap.P1120PSubstitution - coding silentStomach
COSM1749386c.2142A>Tp.E714DSubstitution - MissenseUrinary_tract
COSM3741740c.1708A>Tp.S570CSubstitution - MissenseLiver
COSM1608861c.3066+9A>Gp.?UnknownLiver
COSM5487294c.2597C>Gp.S866WSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM1301593c.193G>Ap.E65KSubstitution - MissenseUrinary_tract
COSM4965933c.4470C>Gp.D1490ESubstitution - MissensePancreas
COSM434564c.1948C>Tp.Q650*Substitution - NonsenseSkin
COSM1197054c.1823G>Ap.S608NSubstitution - MissenseLung
COSM3505520c.584C>Tp.P195LSubstitution - MissenseSkin
COSM1493540c.2998C>Tp.R1000WSubstitution - MissenseKidney
COSM2140836c.758T>Gp.V253GSubstitution - MissenseUpper_aerodigestive_tract
COSM3377741c.2995T>Cp.L999LSubstitution - coding silentPancreas
COSM3794534c.3193G>Cp.E1065QSubstitution - MissenseUrinary_tract
COSM4445637c.2578-3C>Ap.?UnknownSkin
COSM3957078c.416G>Ap.R139KSubstitution - MissenseLung
COSM1375552c.3725delAp.K1245fs*4Deletion - FrameshiftStomach
COSM966702c.1307A>Cp.K436TSubstitution - MissenseEndometrium
COSM4441447c.2154G>Tp.R718SSubstitution - MissenseLarge_intestine
COSM5054602c.3585T>Cp.N1195NSubstitution - coding silentStomach
COSM369424c.4855C>Tp.H1619YSubstitution - MissenseLung
COSM2140950c.3998G>Ap.G1333DSubstitution - MissenseLarge_intestine
COSM4818258c.735C>Tp.L245LSubstitution - coding silentCervix
COSM1200958c.4636C>Tp.R1546*Substitution - NonsenseLarge_intestine
COSM4434001c.1462C>Ap.Q488KSubstitution - MissenseOesophagus
COSM360809c.2843G>Tp.R948LSubstitution - MissenseLung
COSM386702c.1373G>Ap.C458YSubstitution - MissenseLung
COSM3505553c.4738C>Tp.R1580CSubstitution - MissenseSkin
COSM1179445c.4592+1G>Tp.?UnknownProstate
COSM391248c.3724_3725insAp.Y1246fs*13Insertion - FrameshiftLarge_intestine
COSM4758873c.4223G>Tp.R1408MSubstitution - MissenseStomach
COSM1290459c.2105A>Gp.K702RSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM1470863c.820A>Gp.K274ESubstitution - MissenseProstate
COSM966718c.4112A>Cp.N1371TSubstitution - MissenseEndometrium
COSM5508160c.3595+6C>Tp.?UnknownBiliary_tract
COSM4884988c.1835C>Ap.A612DSubstitution - MissenseUpper_aerodigestive_tract
COSM1686226c.4757C>Tp.S1586FSubstitution - MissenseSkin
COSM1290467c.4413+2T>Cp.?UnknownHaematopoietic_and_lymphoid_tissue
COSM2140972c.4318C>Tp.R1440*Substitution - NonsenseLarge_intestine
COSM1375552c.3725delAp.K1245fs*4Deletion - FrameshiftSkin
COSM1375552c.3725delAp.K1245fs*4Deletion - FrameshiftLarge_intestine
COSM4880911c.3300T>Gp.A1100ASubstitution - coding silentProstate
COSM5003424c.3014G>Ap.R1005KSubstitution - MissensePancreas
COSM3817105c.2893A>Gp.K965ESubstitution - MissenseBreast
COSM5433061c.106C>Tp.Q36*Substitution - NonsenseOesophagus
COSM4777670c.4173_4174insAp.Q1392fs*17Insertion - FrameshiftProstate
COSM5004908c.1771G>Ap.A591TSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM2141006c.4980C>Tp.D1660DSubstitution - coding silentLarge_intestine
COSM145234c.1859A>Tp.H620LSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM1290461c.2507G>Cp.R836PSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM1375532c.230C>Ap.P77QSubstitution - MissenseLarge_intestine
COSM1708573c.2108A>Cp.K703TSubstitution - MissenseSkin
COSM1375552c.3725delAp.K1245fs*4Deletion - FrameshiftLarge_intestine
COSM3711879c.4488A>Gp.Q1496QSubstitution - coding silentUpper_aerodigestive_tract
COSM3957082c.4793C>Tp.S1598LSubstitution - MissenseLung
COSM4671962c.360G>Ap.S120SSubstitution - coding silentLarge_intestine
COSM4997242c.2353-123_2360del131p.?UnknownPituitary
COSM1608863c.4835A>Gp.H1612RSubstitution - MissenseLiver
COSM2154697c.5026G>Ap.G1676RSubstitution - MissenseCentral_nervous_system
COSM3505539c.2578-2A>Gp.?UnknownSkin
COSM1608849c.500A>Gp.E167GSubstitution - MissenseLiver
COSM1200956c.3667A>Tp.I1223FSubstitution - MissenseLarge_intestine
COSM3505529c.1866G>Ap.L622LSubstitution - coding silentSkin
COSM4058013c.191C>Tp.S64LSubstitution - MissenseStomach
COSM1659060c.4919G>Ap.W1640*Substitution - NonsenseSalivary_gland
COSM3817099c.569G>Ap.R190HSubstitution - MissenseBreast
COSM5634292c.3401C>Ap.A1134ESubstitution - MissenseOesophagus
COSM4993656c.4097_4098insGCCTCGGp.R1367fs*3Insertion - FrameshiftHaematopoietic_and_lymphoid_tissue
COSM5363131c.3914C>Ap.P1305HSubstitution - MissenseLarge_intestine
COSM1493542c.1199-1G>Ap.?UnknownKidney
COSM3505523c.1453C>Tp.R485*Substitution - NonsenseSkin
COSM3726856c.1172_1173insAp.T392fs*11Insertion - FrameshiftLung
COSM4489196c.3444C>Ap.L1148LSubstitution - coding silentSkin
COSM966710c.2741G>Ap.R914HSubstitution - MissenseEndometrium
COSM1756911c.4459G>Ap.D1487NSubstitution - MissenseUrinary_tract
COSM966692c.585G>Ap.P195PSubstitution - coding silentLarge_intestine
COSM3505531c.1996G>Ap.E666KSubstitution - MissenseSkin
COSM966690c.110C>Tp.S37LSubstitution - MissenseEndometrium
COSM1686226c.4757C>Tp.S1586FSubstitution - MissenseSkin
COSM5350309c.4693-1G>Ap.?UnknownLung
COSM1290463c.3214C>Tp.R1072*Substitution - NonsenseHaematopoietic_and_lymphoid_tissue
COSM391248c.3724_3725insAp.Y1246fs*13Insertion - FrameshiftPancreas
COSM1740894c.2888_2893delTTAATAp.F963_K965>*Complex - deletion inframeHaematopoietic_and_lymphoid_tissue
COSM702075c.543C>Ap.V181VSubstitution - coding silentLung
COSM1200960c.1208G>Ap.R403QSubstitution - MissenseLarge_intestine
COSM4058023c.1403T>Cp.V468ASubstitution - MissenseStomach
COSM279870c.3469G>Tp.A1157SSubstitution - MissenseLarge_intestine
COSM4566710c.4508_4509GG>AAp.R1503QSubstitution - MissenseSkin
COSM2140952c.4000delGp.E1335fs*5Deletion - FrameshiftLarge_intestine
COSM1375536c.515delAp.V175fs*1Deletion - FrameshiftLarge_intestine
COSM3794532c.3175G>Cp.E1059QSubstitution - MissenseUrinary_tract
COSM4972015c.3314C>Tp.T1105MSubstitution - MissenseCentral_nervous_system
COSM145233c.3438T>Gp.F1146LSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM5626215c.3548C>Gp.S1183*Substitution - NonsenseOesophagus
COSM177291c.4319G>Ap.R1440QSubstitution - MissenseEndometrium
COSM1608857c.1419A>Tp.Q473HSubstitution - MissenseLiver
COSM3711879c.4488A>Gp.Q1496QSubstitution - coding silentUpper_aerodigestive_tract
COSM391248c.3724_3725insAp.Y1246fs*13Insertion - FrameshiftLung
COSM3817111c.4578C>Tp.I1526ISubstitution - coding silentBreast
COSM434570c.4197G>Ap.E1399ESubstitution - coding silentBreast
COSM108643c.865A>Tp.N289YSubstitution - MissenseSkin
COSM2140950c.3998G>Ap.G1333DSubstitution - MissenseLarge_intestine
COSM1659897c.604A>Tp.R202*Substitution - NonsenseKidney
COSM4914449c.1898T>Cp.L633PSubstitution - MissenseLiver
COSM966692c.585G>Ap.P195PSubstitution - coding silentEndometrium
COSM1723898c.3296C>Tp.S1099FSubstitution - MissenseSkin
COSM371047c.5154G>Tp.R1718SSubstitution - MissenseLung
COSM108643c.865A>Tp.N289YSubstitution - MissenseSkin
COSM1608859c.2858A>Gp.N953SSubstitution - MissenseLiver
COSM3505518c.41C>Tp.S14LSubstitution - MissenseSkin
COSM3794528c.1585C>Ap.Q529KSubstitution - MissenseUrinary_tract
COSM2140906c.2785G>Ap.A929TSubstitution - MissenseLarge_intestine
COSM4758871c.3494A>Gp.K1165RSubstitution - MissenseStomach
COSM5628037c.327C>Tp.V109VSubstitution - coding silentOesophagus
COSM145232c.3810G>Tp.L1270FSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM1608851c.1160A>Gp.K387RSubstitution - MissenseLiver
COSM5823041c.4400A>Tp.E1467VSubstitution - MissenseLiver
COSM3944339c.3425C>Tp.A1142VSubstitution - MissenseOvary
COSM4929896c.2181G>Cp.Q727HSubstitution - MissenseLiver
COSM966714c.3640G>Ap.G1214RSubstitution - MissenseEndometrium
COSM1375542c.1618G>Ap.V540ISubstitution - MissenseLarge_intestine
COSM3887816c.3381C>Tp.L1127LSubstitution - coding silentCervix
COSM347047c.1256G>Cp.G419ASubstitution - MissenseLung
COSM1686226c.4757C>Tp.S1586FSubstitution - MissenseSkin
COSM1665415c.3760delGp.A1254fs*6Deletion - FrameshiftKidney
COSM1375552c.3725delAp.K1245fs*4Deletion - FrameshiftLarge_intestine
COSM236711c.2782C>Tp.R928WSubstitution - MissenseProstate
COSM4409674c.2937C>Tp.L979LSubstitution - coding silentOesophagus
COSM3361598c.1502A>Cp.K501TSubstitution - MissenseKidney
COSM5054604c.3941C>Tp.A1314VSubstitution - MissenseStomach
COSM5012941c.2095C>Tp.R699WSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM146266c.2094delCp.R699fs*35Deletion - FrameshiftHaematopoietic_and_lymphoid_tissue
COSM471261c.1241T>Cp.L414PSubstitution - MissenseKidney
COSM256614c.4229A>Cp.D1410ASubstitution - MissenseLarge_intestine
COSM1375556c.4969T>Cp.W1657RSubstitution - MissenseStomach
COSM1608849c.500A>Gp.E167GSubstitution - MissenseLiver
COSM4671960c.297G>Ap.M99ISubstitution - MissenseLarge_intestine
COSM5961399c.2357T>Cp.L786PSubstitution - MissenseAdrenal_gland
COSM3505525c.1621C>Tp.P541SSubstitution - MissenseSkin
COSM5126807c.2842C>Tp.R948WSubstitution - MissenseLarge_intestine
COSM1743003c.2798T>Cp.M933TSubstitution - MissenseBiliary_tract
COSM1375558c.5008T>Cp.Y1670HSubstitution - MissenseLarge_intestine
COSM5048906c.2767G>Tp.E923*Substitution - NonsenseOesophagus
COSM1375536c.515delAp.V175fs*1Deletion - FrameshiftStomach
COSM1375556c.4969T>Cp.W1657RSubstitution - MissenseLarge_intestine
COSM1375534c.514_515insAp.V175fs*18Insertion - FrameshiftLarge_intestine
COSM1730030c.3239C>Gp.A1080GSubstitution - MissenseLiver
COSM5417869c.3635T>Cp.I1212TSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM5897892c.1604C>Tp.P535LSubstitution - MissenseSkin
COSM1470865c.275G>Ap.R92QSubstitution - MissenseProstate
COSM4058025c.2706T>Cp.H902HSubstitution - coding silentStomach
COSM4058027c.2977A>Gp.M993VSubstitution - MissenseStomach
COSM966696c.855G>Ap.A285ASubstitution - coding silentEndometrium
COSM1375536c.515delAp.V175fs*1Deletion - FrameshiftStomach
COSM1375546c.2911_2912insTp.L972fs*26Insertion - FrameshiftLarge_intestine
COSM1637747c.3896T>Ap.V1299ESubstitution - MissenseBone
COSM3817107c.3237G>Ap.K1079KSubstitution - coding silentBreast
COSM1375540c.951C>Ap.I317ISubstitution - coding silentLarge_intestine
COSM3817109c.3473G>Ap.R1158HSubstitution - MissenseBreast
COSM145232c.3810G>Tp.L1270FSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM3505541c.2743T>Cp.L915LSubstitution - coding silentSkin
COSM5758229c.2189+1G>Ap.?UnknownBone
COSM5417285c.1880C>Tp.S627FSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM5433330c.1769A>Gp.N590SSubstitution - MissenseOesophagus
COSM1323751c.221A>Gp.K74RSubstitution - MissenseOvary
COSM145233c.3438T>Gp.F1146LSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM5971612c.1195C>Tp.P399SSubstitution - MissenseUpper_aerodigestive_tract
COSM4386065c.3878C>Ap.T1293NSubstitution - MissenseLarge_intestine
COSM1375552c.3725delAp.K1245fs*4Deletion - FrameshiftLarge_intestine
COSM1248199c.3569A>Gp.E1190GSubstitution - MissenseOesophagus
COSM147987c.4623A>Gp.T1541TSubstitution - coding silentStomach
COSM5705989c.62G>Cp.S21TSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM1608853c.1202A>Gp.H401RSubstitution - MissenseLiver
COSM324990c.62G>Ap.S21NSubstitution - MissenseLung
COSM4933823c.1354A>Gp.T452ASubstitution - MissenseLiver
COSM4578633c.907G>Ap.G303SSubstitution - MissenseBone
COSM1608857c.1419A>Tp.Q473HSubstitution - MissenseLiver
COSM4397710c.2497C>Tp.P833SSubstitution - MissenseSkin
COSM3887816c.3381C>Tp.L1127LSubstitution - coding silentSkin
COSM3957080c.2551G>Tp.D851YSubstitution - MissenseLung
COSM6001690c.1907T>Cp.F636SSubstitution - MissenseProstate
COSM5627195c.4525A>Gp.I1509VSubstitution - MissenseOesophagus
COSM4166817c.1038C>Tp.D346DSubstitution - coding silentPituitary
COSM2140812c.192G>Ap.S64SSubstitution - coding silentBiliary_tract
COSM4058039c.4434C>Tp.P1478PSubstitution - coding silentStomach
COSM5479024c.2317G>Tp.E773*Substitution - NonsenseLarge_intestine
COSM5498184c.2908G>Ap.A970TSubstitution - MissenseBiliary_tract
COSM702069c.3582A>Tp.E1194DSubstitution - MissenseLung
COSM1756909c.2338C>Tp.Q780*Substitution - NonsenseUrinary_tract
COSM2154697c.5026G>Ap.G1676RSubstitution - MissenseCentral_nervous_system
COSM4456061c.1343_1344AC>TTp.N448ISubstitution - MissenseSkin
COSM4885877c.678G>Tp.A226ASubstitution - coding silentUpper_aerodigestive_tract
COSM1235314c.1_63-8830del14254p.?UnknownHaematopoietic_and_lymphoid_tissue
COSM1608851c.1160A>Gp.K387RSubstitution - MissenseLiver
COSM1178708c.2T>Cp.M1TSubstitution - MissenseProstate
COSM1608849c.500A>Gp.E167GSubstitution - MissenseLiver
COSM2140940c.3602G>Cp.G1201ASubstitution - MissenseOesophagus
COSM3969351c.1322T>Cp.I441TSubstitution - MissenseCentral_nervous_system
COSM4058017c.671G>Ap.R224QSubstitution - MissenseStomach
COSM4933639c.1337G>Cp.S446TSubstitution - MissenseLiver
COSM4671972c.3205A>Gp.M1069VSubstitution - MissenseLarge_intestine
COSM391248c.3724_3725insAp.Y1246fs*13Insertion - FrameshiftHaematopoietic_and_lymphoid_tissue
COSM1189108c.4203G>Tp.K1401NSubstitution - MissenseLung
COSM1608855c.1242A>Gp.L414LSubstitution - coding silentLiver
COSM3361598c.1502A>Cp.K501TSubstitution - MissenseLarge_intestine
COSM3936902c.4313C>Tp.S1438LSubstitution - MissenseOesophagus
COSM145234c.1859A>Tp.H620LSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM5417637c.724_725insTp.S242fs*3Insertion - FrameshiftHaematopoietic_and_lymphoid_tissue
COSM5384146c.1622C>Tp.P541LSubstitution - MissenseSkin
COSM1723898c.3296C>Tp.S1099FSubstitution - MissenseSkin
COSM3505523c.1453C>Tp.R485*Substitution - NonsenseSkin
> Text Mining based Variations
 
PMID Variation Cancer Evidence
27959900mutationChronic Lymphocytic LeukemiaEspecially, ATM mutation showed 1.5 fold higher incidence than Caucasians, while mutation frequencies of SF3B1, NOTCH1, CHD2 and POT1 tend to be lower in Koreans than in Caucasians.
Summary
SymbolCHD2
Namechromodomain helicase DNA binding protein 2
Aliases FLJ38614; DKFZp547I1315; DKFZp781D1727; DKFZp686E01200; EEOC; ATP-dependent helicase CHD2; CHD-2; Chromodoma ......
Location15q26.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Post-translational modification (PTM)
> Post-translational modification (PTM)
 
 Filter By:
Uniprot ID Position Amino Acid Description Upstream Enzyme Affected By Mutation Amino Acid Sequence Variant
O14647208SPhosphoserine-NoNone detected
O14647240TPhosphothreonine-NoNone detected
O14647242SPhosphoserine-NoNone detected
O146471085SPhosphoserine-Yesp.S1085G (cancer: SARC)
O146471087SPhosphoserine-NoNone detected
O146471365SPhosphoserine-NoNone detected
O146471386SPhosphoserine-NoNone detected
O146471807SPhosphoserine-NoNone detected
Summary
SymbolCHD2
Namechromodomain helicase DNA binding protein 2
Aliases FLJ38614; DKFZp547I1315; DKFZp781D1727; DKFZp686E01200; EEOC; ATP-dependent helicase CHD2; CHD-2; Chromodoma ......
Location15q26.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Expression analysis in primary tumor tissue from TCGA
> Expression level in cancer cell line from CCLE
> Expression level in human normal tissue from HPA
> Text mining based expression change
> The Cancer Genome Atlas (TCGA)
 


  Differential expression analysis for cancers with more than 10 normal samples
Cancer Full Name # N # T Median (N) Median (T) LogFC Adj. P Status
BLCABladder urothelial carcinoma194087.0616.472-0.5290.000127NS
BRCABreast invasive carcinoma11211007.1456.817-0.3641.26e-13NS
CESCCervical and endocervical cancers33066.9276.628NANANA
COADColon adenocarcinoma414596.4816.334-0.0930.369NS
ESCAEsophageal carcinoma111857.3486.933-0.3790.00772NS
GBMGlioblastoma multiforme51666.7516.312NANANA
HNSCHead and Neck squamous cell carcinoma445226.6696.486-0.1190.174NS
KIRCKidney renal clear cell carcinoma725346.7256.740.0270.661NS
KIRPKidney renal papillary cell carcinoma322916.6036.487-0.1950.0253NS
LAMLAcute Myeloid Leukemia0173NA7.9NANANA
LGGBrain Lower Grade Glioma0530NA7.155NANANA
LIHCLiver hepatocellular carcinoma503735.5255.443-0.1650.049NS
LUADLung adenocarcinoma595177.0226.914-0.0690.472NS
LUSCLung squamous cell carcinoma515016.9586.624-0.3821.1e-05NS
OVOvarian serous cystadenocarcinoma0307NA6.205NANANA
PAADPancreatic adenocarcinoma41796.8016.818NANANA
PCPGPheochromocytoma and Paraganglioma31846.2786.54NANANA
PRADProstate adenocarcinoma524986.9526.874-0.0370.585NS
READRectum adenocarcinoma101676.3526.2870.0050.986NS
SARCSarcoma22636.1266.439NANANA
SKCMSkin Cutaneous Melanoma14726.5946.462NANANA
STADStomach adenocarcinoma354156.7056.7490.0710.465NS
TGCTTesticular Germ Cell Tumors0156NA6.815NANANA
THCAThyroid carcinoma595097.3997.131-0.2975.86e-08NS
THYMThymoma21207.4576.948NANANA
UCECUterine Corpus Endometrial Carcinoma355466.8546.358-0.5595.21e-12NS
> Cancer Cell Line Encyclopedia (CCLE)
 



Tissue Cell Line Expression Level (Microarray)
Autonomic ganglia CHP126 7.6
Autonomic ganglia CHP212 7.7
Autonomic ganglia IMR32 7.9
Autonomic ganglia KELLY 7.6
Autonomic ganglia KPNRTBM1 7.8
Autonomic ganglia KPNSI9S 7.2
Autonomic ganglia KPNYN 7.4
Autonomic ganglia MHHNB11 8.2
Autonomic ganglia NB1 7.6
Autonomic ganglia NH6 7.2
Autonomic ganglia SHSY5Y 7.9
Autonomic ganglia SIMA 7.8
Autonomic ganglia SKNAS 7.9
Autonomic ganglia SKNBE2 7.8
Autonomic ganglia SKNDZ 7.1
Autonomic ganglia SKNFI 8
Autonomic ganglia SKNSH 7.4
Biliary tract HUCCT1 7.8
Biliary tract HUH28 7.5
Biliary tract SNU1079 7.2
Biliary tract SNU1196 8
Biliary tract SNU245 7.6
Biliary tract SNU308 7.4
Biliary tract SNU478 7.8
Bone 143B 7.3
Bone A673 7.8
Bone CADOES1 7.9
Bone CAL78 8.1
Bone G292CLONEA141B1 6.3
Bone HOS 8.1
Bone HS706T 7.1
Bone HS737T 7.2
Bone HS819T 7.6
Bone HS821T 7.7
Bone HS822T 7.6
Bone HS863T 8
Bone HS870T 7.5
Bone HS888T 8.1
Bone MG63 7.6
Bone MHHES1 8.3
Bone OUMS27 7.4
Bone RDES 7.2
Bone SJSA1 7.5
Bone SKES1 7.5
Bone SKNMC 7.4
Bone SW1353 7.1
Bone T173 7.2
Bone TC71 7.5
Bone U2OS 7.6
Breast AU565 7.6
Breast BT20 8.1
Breast BT474 7.3
Breast BT483 7.8
Breast BT549 7.1
Breast CAL120 7.8
Breast CAL148 7.4
Breast CAL51 8.4
Breast CAL851 7.5
Breast CAMA1 7.5
Breast DU4475 7.8
Breast EFM192A 7.5
Breast EFM19 9.7
Breast EVSAT 7.4
Breast HCC1143 8.1
Breast HCC1187 7.7
Breast HCC1395 8.4
Breast HCC1419 8.5
Breast HCC1428 7.5
Breast HCC1500 7.8
Breast HCC1569 7.3
Breast HCC1599 7.6
Breast HCC1806 7.9
Breast HCC1937 8.5
Breast HCC1954 7.9
Breast HCC202 7.2
Breast HCC2157 7.7
Breast HCC2218 7.1
Breast HCC38 7.8
Breast HCC70 7.5
Breast HDQP1 7.9
Breast HMC18 8.4
Breast HS274T 7
Breast HS281T 7.8
Breast HS343T 7.4
Breast HS578T 7.8
Breast HS606T 7.9
Breast HS739T 7.7
Breast HS742T 7.8
Breast JIMT1 8.3
Breast KPL1 8.3
Breast MCF7 8
Breast MDAMB134VI 7.8
Breast MDAMB157 7.9
Breast MDAMB175VII 7.7
Breast MDAMB231 7.3
Breast MDAMB361 6.5
Breast MDAMB415 8.6
Breast MDAMB436 7.8
Breast MDAMB453 7.8
Breast MDAMB468 7
Breast SKBR3 7.6
Breast T47D 7.7
Breast UACC812 7.5
Breast UACC893 7.4
Breast YMB1 8.4
Breast ZR751 8.4
Breast ZR7530 8
Central nervous system 1321N1 7.8
Central nervous system 42MGBA 8.5
Central nervous system 8MGBA 7.7
Central nervous system A172 6.9
Central nervous system AM38 7.8
Central nervous system BECKER 7.9
Central nervous system CAS1 7.5
Central nervous system CCFSTTG1 7
Central nervous system D283MED 8.2
Central nervous system D341MED 7.5
Central nervous system DAOY 7.8
Central nervous system DBTRG05MG 8.1
Central nervous system DKMG 7.8
Central nervous system GAMG 7.6
Central nervous system GB1 7
Central nervous system GI1 7.5
Central nervous system GMS10 8.2
Central nervous system GOS3 7.4
Central nervous system H4 8.2
Central nervous system HS683 7.1
Central nervous system KALS1 7.4
Central nervous system KG1C 7.7
Central nervous system KNS42 7.4
Central nervous system KNS60 7.5
Central nervous system KNS81 7.2
Central nervous system KS1 7
Central nervous system LN18 8.8
Central nervous system LN229 7.6
Central nervous system M059K 7.4
Central nervous system MOGGCCM 6.9
Central nervous system MOGGUVW 8
Central nervous system NMCG1 7.8
Central nervous system ONS76 7.7
Central nervous system SF126 8.1
Central nervous system SF295 7.4
Central nervous system SNB19 7.4
Central nervous system SNU1105 7.6
Central nervous system SNU201 7.6
Central nervous system SNU466 7.5
Central nervous system SNU489 7.8
Central nervous system SNU626 7.1
Central nervous system SNU738 7.2
Central nervous system SW1088 7.4
Central nervous system SW1783 7.2
Central nervous system T98G 7
Central nervous system TM31 8.6
Central nervous system U118MG 7.9
Central nervous system U138MG 8.1
Central nervous system U251MG 7.7
Central nervous system U87MG 7.8
Central nervous system YH13 7.8
Central nervous system YKG1 7.1
Endometrium AN3CA 6.8
Endometrium COLO684 7.9
Endometrium EFE184 7.3
Endometrium EN 8.2
Endometrium ESS1 7.9
Endometrium HEC108 7.6
Endometrium HEC151 7.7
Endometrium HEC1A 7.5
Endometrium HEC1B 7.9
Endometrium HEC251 8.2
Endometrium HEC265 7.3
Endometrium HEC50B 8.6
Endometrium HEC59 6.6
Endometrium HEC6 8
Endometrium ISHIKAWAHERAKLIO02ER 7.5
Endometrium JHUEM1 8
Endometrium JHUEM2 7.6
Endometrium JHUEM3 8.4
Endometrium KLE 6.8
Endometrium MFE280 6.9
Endometrium MFE296 7.3
Endometrium MFE319 7.8
Endometrium RL952 7.5
Endometrium SNGM 7.8
Endometrium SNU1077 7.4
Endometrium SNU685 7.6
Endometrium TEN 7.9
Haematopoietic and lymphoid 697 8.6
Haematopoietic and lymphoid A3KAW 8.3
Haematopoietic and lymphoid A4FUK 8.3
Haematopoietic and lymphoid ALLSIL 8
Haematopoietic and lymphoid AML193 7
Haematopoietic and lymphoid AMO1 9.2
Haematopoietic and lymphoid BCP1 7.9
Haematopoietic and lymphoid BDCM 8.5
Haematopoietic and lymphoid BL41 8.6
Haematopoietic and lymphoid BL70 7.3
Haematopoietic and lymphoid BV173 8.2
Haematopoietic and lymphoid CA46 9.7
Haematopoietic and lymphoid CI1 7.7
Haematopoietic and lymphoid CMK115 9
Haematopoietic and lymphoid CMK86 7.9
Haematopoietic and lymphoid CMK 9.1
Haematopoietic and lymphoid CMLT1 8.8
Haematopoietic and lymphoid COLO775 9.4
Haematopoietic and lymphoid DAUDI 7.7
Haematopoietic and lymphoid DB 6.1
Haematopoietic and lymphoid DEL 8.4
Haematopoietic and lymphoid DND41 8.4
Haematopoietic and lymphoid DOHH2 7.7
Haematopoietic and lymphoid EB1 9.1
Haematopoietic and lymphoid EB2 9.1
Haematopoietic and lymphoid EHEB 9.1
Haematopoietic and lymphoid EJM 9.2
Haematopoietic and lymphoid EM2 7.9
Haematopoietic and lymphoid EOL1 7.4
Haematopoietic and lymphoid F36P 8.4
Haematopoietic and lymphoid GA10 8.3
Haematopoietic and lymphoid GDM1 8
Haematopoietic and lymphoid GRANTA519 9.8
Haematopoietic and lymphoid HDLM2 4.2
Haematopoietic and lymphoid HDMYZ 8.3
Haematopoietic and lymphoid HEL9217 8.1
Haematopoietic and lymphoid HEL 9
Haematopoietic and lymphoid HH 7.7
Haematopoietic and lymphoid HL60 7.5
Haematopoietic and lymphoid HPBALL 8.8
Haematopoietic and lymphoid HS604T 7.3
Haematopoietic and lymphoid HS611T 7.9
Haematopoietic and lymphoid HS616T 7.6
Haematopoietic and lymphoid HS751T 7.6
Haematopoietic and lymphoid HT 6.3
Haematopoietic and lymphoid HTK 7.7
Haematopoietic and lymphoid HUNS1 8.2
Haematopoietic and lymphoid HUT102 8.3
Haematopoietic and lymphoid HUT78 8
Haematopoietic and lymphoid JEKO1 8.9
Haematopoietic and lymphoid JK1 9.7
Haematopoietic and lymphoid JM1 8.3
Haematopoietic and lymphoid JURKAT 8.5
Haematopoietic and lymphoid JURLMK1 8.5
Haematopoietic and lymphoid JVM2 9.4
Haematopoietic and lymphoid JVM3 9.3
Haematopoietic and lymphoid K562 8.2
Haematopoietic and lymphoid KARPAS299 9
Haematopoietic and lymphoid KARPAS422 6.7
Haematopoietic and lymphoid KARPAS620 9.1
Haematopoietic and lymphoid KASUMI1 7.9
Haematopoietic and lymphoid KASUMI2 7.9
Haematopoietic and lymphoid KASUMI6 8.1
Haematopoietic and lymphoid KCL22 8.4
Haematopoietic and lymphoid KE37 8.6
Haematopoietic and lymphoid KE97 8.8
Haematopoietic and lymphoid KG1 8.1
Haematopoietic and lymphoid KHM1B 8.5
Haematopoietic and lymphoid KIJK 5.9
Haematopoietic and lymphoid KMH2 8.2
Haematopoietic and lymphoid KMM1 8.7
Haematopoietic and lymphoid KMS11 8.4
Haematopoietic and lymphoid KMS12BM 8.1
Haematopoietic and lymphoid KMS18 9.5
Haematopoietic and lymphoid KMS20 8.2
Haematopoietic and lymphoid KMS21BM 8.5
Haematopoietic and lymphoid KMS26 8.7
Haematopoietic and lymphoid KMS27 8.7
Haematopoietic and lymphoid KMS28BM 8.1
Haematopoietic and lymphoid KMS34 8.3
Haematopoietic and lymphoid KO52 8.1
Haematopoietic and lymphoid KOPN8 8.2
Haematopoietic and lymphoid KU812 8.8
Haematopoietic and lymphoid KYO1 8.4
Haematopoietic and lymphoid L1236 7
Haematopoietic and lymphoid L363 10
Haematopoietic and lymphoid L428 7.8
Haematopoietic and lymphoid L540 8.9
Haematopoietic and lymphoid LAMA84 8.8
Haematopoietic and lymphoid LOUCY 8.9
Haematopoietic and lymphoid LP1 9.2
Haematopoietic and lymphoid M07E 8.8
Haematopoietic and lymphoid MC116 9
Haematopoietic and lymphoid ME1 7.3
Haematopoietic and lymphoid MEC1 10.1
Haematopoietic and lymphoid MEC2 9.9
Haematopoietic and lymphoid MEG01 8.5
Haematopoietic and lymphoid MHHCALL2 8.9
Haematopoietic and lymphoid MHHCALL3 8.1
Haematopoietic and lymphoid MHHCALL4 8.6
Haematopoietic and lymphoid MINO 8.6
Haematopoietic and lymphoid MJ 8.1
Haematopoietic and lymphoid MM1S 7.7
Haematopoietic and lymphoid MOLM13 7.6
Haematopoietic and lymphoid MOLM16 8.6
Haematopoietic and lymphoid MOLM6 7.5
Haematopoietic and lymphoid MOLP2 8.8
Haematopoietic and lymphoid MOLP8 8.5
Haematopoietic and lymphoid MOLT13 8.6
Haematopoietic and lymphoid MOLT16 8.7
Haematopoietic and lymphoid MOLT4 7.9
Haematopoietic and lymphoid MONOMAC1 7.2
Haematopoietic and lymphoid MONOMAC6 8.3
Haematopoietic and lymphoid MOTN1 8
Haematopoietic and lymphoid MUTZ5 8.4
Haematopoietic and lymphoid MV411 7.2
Haematopoietic and lymphoid NALM19 7.9
Haematopoietic and lymphoid NALM1 8.6
Haematopoietic and lymphoid NALM6 8.6
Haematopoietic and lymphoid NAMALWA 8.5
Haematopoietic and lymphoid NB4 7.6
Haematopoietic and lymphoid NCIH929 7.5
Haematopoietic and lymphoid NCO2 7.8
Haematopoietic and lymphoid NOMO1 7.8
Haematopoietic and lymphoid NUDHL1 8.8
Haematopoietic and lymphoid NUDUL1 8
Haematopoietic and lymphoid OCIAML2 7.1
Haematopoietic and lymphoid OCIAML3 8.3
Haematopoietic and lymphoid OCIAML5 7.9
Haematopoietic and lymphoid OCILY10 5.8
Haematopoietic and lymphoid OCILY19 9.4
Haematopoietic and lymphoid OCILY3 8.5
Haematopoietic and lymphoid OCIM1 9.1
Haematopoietic and lymphoid OPM2 9.3
Haematopoietic and lymphoid P12ICHIKAWA 8.6
Haematopoietic and lymphoid P31FUJ 8.4
Haematopoietic and lymphoid P3HR1 6.9
Haematopoietic and lymphoid PCM6 9.8
Haematopoietic and lymphoid PEER 8.5
Haematopoietic and lymphoid PF382 9.4
Haematopoietic and lymphoid PFEIFFER 7.6
Haematopoietic and lymphoid PL21 8.2
Haematopoietic and lymphoid RAJI 7.2
Haematopoietic and lymphoid RCHACV 8.2
Haematopoietic and lymphoid REC1 8.8
Haematopoietic and lymphoid REH 7.7
Haematopoietic and lymphoid RI1 8.3
Haematopoietic and lymphoid RL 6.8
Haematopoietic and lymphoid RPMI8226 8.9
Haematopoietic and lymphoid RPMI8402 8.3
Haematopoietic and lymphoid RS411 7.9
Haematopoietic and lymphoid SEM 7.9
Haematopoietic and lymphoid SET2 8.5
Haematopoietic and lymphoid SIGM5 8.1
Haematopoietic and lymphoid SKM1 7.5
Haematopoietic and lymphoid SKMM2 8.5
Haematopoietic and lymphoid SR786 9.1
Haematopoietic and lymphoid ST486 8.6
Haematopoietic and lymphoid SUDHL10 7.8
Haematopoietic and lymphoid SUDHL1 8.8
Haematopoietic and lymphoid SUDHL4 6.9
Haematopoietic and lymphoid SUDHL5 7.6
Haematopoietic and lymphoid SUDHL6 8.7
Haematopoietic and lymphoid SUDHL8 8.2
Haematopoietic and lymphoid SUPB15 7.7
Haematopoietic and lymphoid SUPHD1 7.8
Haematopoietic and lymphoid SUPM2 9.2
Haematopoietic and lymphoid SUPT11 8.9
Haematopoietic and lymphoid SUPT1 8.2
Haematopoietic and lymphoid TALL1 8.5
Haematopoietic and lymphoid TF1 7.2
Haematopoietic and lymphoid THP1 7.6
Haematopoietic and lymphoid TO175T 7.5
Haematopoietic and lymphoid TOLEDO 8.1
Haematopoietic and lymphoid U266B1 8.7
Haematopoietic and lymphoid U937 8.1
Haematopoietic and lymphoid UT7 7.8
Haematopoietic and lymphoid WSUDLCL2 8.4
Kidney 769P 7.5
Kidney 786O 7.2
Kidney A498 7.6
Kidney A704 7.2
Kidney ACHN 7.5
Kidney BFTC909 8.2
Kidney CAKI1 7.7
Kidney CAKI2 8.3
Kidney CAL54 7.4
Kidney KMRC1 7.2
Kidney KMRC20 7.8
Kidney KMRC2 6.7
Kidney KMRC3 7.1
Kidney OSRC2 8.4
Kidney RCC10RGB 8.4
Kidney SNU1272 6.8
Kidney SNU349 6.8
Kidney TUHR10TKB 7.3
Kidney TUHR14TKB 7.8
Kidney TUHR4TKB 7.2
Kidney VMRCRCW 8.1
Kidney VMRCRCZ 7.8
Large intestine C2BBE1 7.5
Large intestine CCK81 7.6
Large intestine CL11 8.4
Large intestine CL14 8.2
Large intestine CL34 8.8
Large intestine CL40 7.8
Large intestine COLO205 7.9
Large intestine COLO320 7.8
Large intestine COLO678 8.1
Large intestine CW2 7.8
Large intestine DLD1 8
Large intestine GP2D 8.4
Large intestine HCC56 7.6
Large intestine HCT116 7.3
Large intestine HCT15 8
Large intestine HS675T 7.8
Large intestine HS698T 7.2
Large intestine HT115 7.6
Large intestine HT29 8.5
Large intestine HT55 8.5
Large intestine KM12 9.1
Large intestine LOVO 8
Large intestine LS1034 9
Large intestine LS123 8.2
Large intestine LS180 8.1
Large intestine LS411N 8.7
Large intestine LS513 7.8
Large intestine MDST8 7.8
Large intestine NCIH508 7.8
Large intestine NCIH716 7.4
Large intestine NCIH747 7.2
Large intestine OUMS23 8.2
Large intestine RCM1 8.5
Large intestine RKO 7.4
Large intestine SKCO1 7.7
Large intestine SNU1040 6.8
Large intestine SNU1197 8.7
Large intestine SNU175 7.7
Large intestine SNU283 7.9
Large intestine SNU407 7.5
Large intestine SNU503 8.8
Large intestine SNU61 8.1
Large intestine SNU81 8.7
Large intestine SNUC1 7.1
Large intestine SNUC2A 8.5
Large intestine SNUC4 7.9
Large intestine SNUC5 8.5
Large intestine SW1116 8.4
Large intestine SW1417 7.9
Large intestine SW1463 7.3
Large intestine SW403 7.8
Large intestine SW480 7.6
Large intestine SW48 8.3
Large intestine SW620 8
Large intestine SW837 8.2
Large intestine SW948 8.1
Large intestine T84 7.7
Liver ALEXANDERCELLS 7.4
Liver C3A 8
Liver HEP3B217 7.8
Liver HEPG2 7.8
Liver HLE 7
Liver HLF 7.1
Liver HUH1 8.1
Liver HUH6 8.4
Liver HUH7 7.8
Liver JHH1 7
Liver JHH2 5.8
Liver JHH4 7.7
Liver JHH5 7.7
Liver JHH6 7.6
Liver JHH7 8.4
Liver LI7 8.2
Liver PLCPRF5 7.2
Liver SKHEP1 7.8
Liver SNU182 7
Liver SNU387 7.2
Liver SNU398 8.1
Liver SNU423 6.6
Liver SNU449 6.7
Liver SNU475 7.7
Liver SNU761 7.3
Liver SNU878 6.8
Liver SNU886 7.8
Lung A549 7.5
Lung ABC1 8
Lung BEN 8.2
Lung CAL12T 8.4
Lung CALU1 7.6
Lung CALU3 7.8
Lung CALU6 8
Lung CHAGOK1 7.6
Lung COLO668 8.3
Lung COLO699 7.3
Lung CORL105 8.1
Lung CORL23 8.2
Lung CORL24 7.8
Lung CORL279 7.7
Lung CORL311 8
Lung CORL47 9.1
Lung CORL51 8.1
Lung CORL88 7.6
Lung CORL95 8
Lung CPCN 7.7
Lung DMS114 8.3
Lung DMS153 7.8
Lung DMS273 6.8
Lung DMS454 8.9
Lung DMS53 7.5
Lung DMS79 7.7
Lung DV90 7
Lung EBC1 7.6
Lung EPLC272H 7.9
Lung HARA 8.2
Lung HCC1171 8.2
Lung HCC1195 7.5
Lung HCC15 7.6
Lung HCC2279 7.1
Lung HCC2935 8.2
Lung HCC33 8.6
Lung HCC366 8.3
Lung HCC4006 8.4
Lung HCC44 7.2
Lung HCC78 9.1
Lung HCC827 7.3
Lung HCC95 8.9
Lung HLC1 8
Lung HLFA 7.7
Lung HS229T 7.5
Lung HS618T 7.6
Lung IALM 7.9
Lung KNS62 7.9
Lung LC1F 7.7
Lung LC1SQSF 7.5
Lung LCLC103H 8.9
Lung LCLC97TM1 9
Lung LK2 8
Lung LOUNH91 7.3
Lung LU65 7.4
Lung LU99 7.8
Lung LUDLU1 8.4
Lung LXF289 7.6
Lung MORCPR 9.1
Lung NCIH1048 7.8
Lung NCIH1092 8
Lung NCIH1105 8.1
Lung NCIH1155 7.2
Lung NCIH1184 7.9
Lung NCIH1299 7.4
Lung NCIH1339 8.2
Lung NCIH1341 7.6
Lung NCIH1355 8.2
Lung NCIH1373 7.9
Lung NCIH1385 8.5
Lung NCIH1395 7.7
Lung NCIH1435 9.1
Lung NCIH1436 8.7
Lung NCIH1437 8
Lung NCIH146 7.9
Lung NCIH1563 7
Lung NCIH1568 8
Lung NCIH1573 8.3
Lung NCIH1581 7.9
Lung NCIH1618 7.8
Lung NCIH1623 7.8
Lung NCIH1648 8.7
Lung NCIH1650 8.3
Lung NCIH1651 6.5
Lung NCIH1666 7.4
Lung NCIH1693 8
Lung NCIH1694 8.2
Lung NCIH1703 7.5
Lung NCIH1734 7.5
Lung NCIH1755 7
Lung NCIH1781 7.7
Lung NCIH1792 6.7
Lung NCIH1793 7.9
Lung NCIH1836 7.5
Lung NCIH1838 8
Lung NCIH1869 8.3
Lung NCIH1876 8.3
Lung NCIH1915 8.1
Lung NCIH1930 7.3
Lung NCIH1944 8.1
Lung NCIH1963 8.2
Lung NCIH196 7.7
Lung NCIH1975 7.6
Lung NCIH2009 7.9
Lung NCIH2023 7.2
Lung NCIH2029 7.6
Lung NCIH2030 8.3
Lung NCIH2066 7.6
Lung NCIH2081 8.7
Lung NCIH2085 7.6
Lung NCIH2087 8.2
Lung NCIH209 8.5
Lung NCIH2106 7.8
Lung NCIH2110 7.5
Lung NCIH211 8.2
Lung NCIH2122 8.5
Lung NCIH2126 9.2
Lung NCIH2141 8
Lung NCIH2170 7.4
Lung NCIH2171 8.2
Lung NCIH2172 8.7
Lung NCIH2196 7.3
Lung NCIH2227 7.3
Lung NCIH2228 7.5
Lung NCIH226 7.9
Lung NCIH2286 8.5
Lung NCIH2291 7.7
Lung NCIH2342 8.1
Lung NCIH2347 8
Lung NCIH23 6.7
Lung NCIH2405 8
Lung NCIH2444 7.8
Lung NCIH292 7.4
Lung NCIH322 8.7
Lung NCIH3255 7.6
Lung NCIH358 8.5
Lung NCIH441 8.7
Lung NCIH446 7.5
Lung NCIH460 7.1
Lung NCIH510 7.7
Lung NCIH520 8.2
Lung NCIH522 7.7
Lung NCIH524 8.3
Lung NCIH526 8.2
Lung NCIH596 8.7
Lung NCIH647 7.4
Lung NCIH650 8.4
Lung NCIH661 6.6
Lung NCIH69 7
Lung NCIH727 9.1
Lung NCIH810 8.3
Lung NCIH82 7.8
Lung NCIH838 8.5
Lung NCIH841 7.2
Lung NCIH854 7.7
Lung NCIH889 7.8
Lung PC14 7.5
Lung RERFLCAD1 8.9
Lung RERFLCAD2 7.6
Lung RERFLCAI 7
Lung RERFLCKJ 8
Lung RERFLCMS 7.3
Lung RERFLCSQ1 7.6
Lung SBC5 8.3
Lung SCLC21H 8.4
Lung SHP77 7.4
Lung SKLU1 7
Lung SKMES1 8.4
Lung SQ1 6.9
Lung SW1271 7.9
Lung SW1573 7.3
Lung SW900 8.1
Lung VMRCLCD 7
Lung VMRCLCP 8.4
Oesophagus COLO680N 8.9
Oesophagus ECGI10 8.6
Oesophagus KYSE140 7.5
Oesophagus KYSE150 8.6
Oesophagus KYSE180 7.5
Oesophagus KYSE270 7
Oesophagus KYSE30 8.5
Oesophagus KYSE410 7.7
Oesophagus KYSE450 8.4
Oesophagus KYSE510 8.4
Oesophagus KYSE520 8.2
Oesophagus KYSE70 7.9
Oesophagus OE19 7
Oesophagus OE33 7.9
Oesophagus TE10 9
Oesophagus TE11 8
Oesophagus TE14 9.2
Oesophagus TE15 8.5
Oesophagus TE1 7.4
Oesophagus TE4 8.5
Oesophagus TE5 7.4
Oesophagus TE6 8.7
Oesophagus TE8 8.3
Oesophagus TE9 8.3
Oesophagus TT 9.3
Ovary 59M 7.5
Ovary A2780 8.2
Ovary CAOV3 7.5
Ovary CAOV4 7.8
Ovary COLO704 8.1
Ovary COV318 7.5
Ovary COV362 7.8
Ovary COV434 8.3
Ovary COV504 7.6
Ovary COV644 7.4
Ovary EFO21 7.7
Ovary EFO27 8
Ovary ES2 6.9
Ovary FUOV1 7.6
Ovary HEYA8 8
Ovary HS571T 7.5
Ovary IGROV1 8
Ovary JHOC5 8.9
Ovary JHOM1 8.8
Ovary JHOM2B 8.5
Ovary JHOS2 7.4
Ovary JHOS4 8.5
Ovary KURAMOCHI 7.6
Ovary MCAS 8.2
Ovary NIHOVCAR3 7.2
Ovary OAW28 7.1
Ovary OAW42 6.5
Ovary OC314 7
Ovary OC316 7
Ovary ONCODG1 7.4
Ovary OV56 8.8
Ovary OV7 7.9
Ovary OV90 8.1
Ovary OVCAR4 7.4
Ovary OVCAR8 6.9
Ovary OVISE 6.8
Ovary OVK18 7
Ovary OVKATE 7.8
Ovary OVMANA 7.9
Ovary OVSAHO 6.8
Ovary OVTOKO 7.1
Ovary RMGI 8.3
Ovary RMUGS 7.8
Ovary SKOV3 7.5
Ovary SNU119 7.8
Ovary SNU840 7.8
Ovary SNU8 7.2
Ovary TOV112D 7.4
Ovary TOV21G 7.7
Ovary TYKNU 7.2
Pancreas ASPC1 8.3
Pancreas BXPC3 8.4
Pancreas CAPAN1 8
Pancreas CAPAN2 8.3
Pancreas CFPAC1 8.6
Pancreas DANG 7.3
Pancreas HPAC 8.8
Pancreas HPAFII 7.9
Pancreas HS766T 7.3
Pancreas HUPT3 7.5
Pancreas HUPT4 8.1
Pancreas KCIMOH1 8.1
Pancreas KLM1 8.9
Pancreas KP2 8.3
Pancreas KP3 8.6
Pancreas KP4 7.8
Pancreas L33 8.8
Pancreas MIAPACA2 7
Pancreas PANC0203 8.6
Pancreas PANC0213 8.6
Pancreas PANC0327 7.7
Pancreas PANC0403 8.5
Pancreas PANC0504 8.3
Pancreas PANC0813 8.4
Pancreas PANC1005 8.5
Pancreas PANC1 7.4
Pancreas PATU8902 8.1
Pancreas PATU8988S 7.3
Pancreas PATU8988T 6.7
Pancreas PK1 8.3
Pancreas PK45H 7.8
Pancreas PK59 8.4
Pancreas PL45 8.4
Pancreas PSN1 7.5
Pancreas QGP1 8.9
Pancreas SNU213 8.4
Pancreas SNU324 8
Pancreas SNU410 7.7
Pancreas SU8686 9.8
Pancreas SUIT2 7.1
Pancreas SW1990 7.7
Pancreas T3M4 8.4
Pancreas TCCPAN2 7.7
Pancreas YAPC 8.8
Pleura ACCMESO1 7.9
Pleura DM3 7.8
Pleura ISTMES1 7
Pleura ISTMES2 7.5
Pleura JL1 7.8
Pleura MPP89 7.9
Pleura MSTO211H 7.7
Pleura NCIH2052 7.8
Pleura NCIH2452 8
Pleura NCIH28 7.4
Prostate 22RV1 7.9
Prostate DU145 7.4
Prostate LNCAPCLONEFGC 8.4
Prostate MDAPCA2B 8
Prostate NCIH660 7.4
Prostate PC3 6.5
Prostate VCAP 8.7
Salivary gland A253 7.9
Salivary gland YD15 8.1
Skin A101D 7.3
Skin A2058 7.2
Skin A375 7.8
Skin C32 7.7
Skin CHL1 7.2
Skin CJM 9.5
Skin COLO679 7.1
Skin COLO741 8
Skin COLO783 8.5
Skin COLO792 6.5
Skin COLO800 8
Skin COLO818 8.5
Skin COLO829 8.5
Skin COLO849 7.7
Skin G361 7.6
Skin GRM 7.3
Skin HMCB 7.4
Skin HS294T 6.8
Skin HS600T 7.6
Skin HS688AT 7.2
Skin HS695T 7.2
Skin HS839T 7.5
Skin HS852T 7
Skin HS895T 7.9
Skin HS934T 7.6
Skin HS936T 7
Skin HS939T 7.5
Skin HS940T 7.6
Skin HS944T 6.8
Skin HT144 7.7
Skin IGR1 8.2
Skin IGR37 7
Skin IGR39 7.7
Skin IPC298 7.6
Skin K029AX 7.1
Skin LOXIMVI 7.7
Skin MALME3M 7.1
Skin MDAMB435S 8.9
Skin MELHO 7.4
Skin MELJUSO 7.3
Skin MEWO 7.6
Skin RPMI7951 8.4
Skin RVH421 7.3
Skin SH4 7.6
Skin SKMEL1 7.6
Skin SKMEL24 8.3
Skin SKMEL28 7.8
Skin SKMEL2 6.7
Skin SKMEL30 7.2
Skin SKMEL31 7.5
Skin SKMEL3 7.6
Skin SKMEL5 6.8
Skin UACC257 7
Skin UACC62 7.3
Skin WM115 6.9
Skin WM1799 8.3
Skin WM2664 7.1
Skin WM793 7.5
Skin WM88 7.6
Skin WM983B 8.1
Small intestine HUTU80 7.7
Soft tissue A204 7.8
Soft tissue G401 7.7
Soft tissue G402 7.7
Soft tissue GCT 7.8
Soft tissue HS729 6.9
Soft tissue HT1080 8.2
Soft tissue KYM1 7.7
Soft tissue MESSA 8.7
Soft tissue RD 8
Soft tissue RH30 7
Soft tissue RH41 7.6
Soft tissue RKN 7.7
Soft tissue S117 7.5
Soft tissue SJRH30 8
Soft tissue SKLMS1 7.7
Soft tissue SKUT1 8
Soft tissue TE125T 7.7
Soft tissue TE159T 7.3
Soft tissue TE441T 8.1
Soft tissue TE617T 8.6
Stomach 2313287 8.3
Stomach AGS 8.1
Stomach AZ521 7.7
Stomach ECC10 8.3
Stomach ECC12 8.4
Stomach FU97 7.7
Stomach GCIY 7.3
Stomach GSS 8.1
Stomach GSU 8.1
Stomach HGC27 7.9
Stomach HS746T 8
Stomach HUG1N 7.5
Stomach IM95 8.3
Stomach KATOIII 8.1
Stomach KE39 8.4
Stomach LMSU 7.8
Stomach MKN1 7.4
Stomach MKN45 8.1
Stomach MKN74 10
Stomach MKN7 8.4
Stomach NCCSTCK140 8.8
Stomach NCIN87 7.7
Stomach NUGC2 7.4
Stomach NUGC3 7.7
Stomach NUGC4 7.8
Stomach OCUM1 7.9
Stomach RERFGC1B 8.1
Stomach SH10TC 8.1
Stomach SNU16 7.8
Stomach SNU1 8
Stomach SNU216 8.6
Stomach SNU520 8.2
Stomach SNU5 6.8
Stomach SNU601 7.3
Stomach SNU620 8.2
Stomach SNU668 7.5
Stomach SNU719 8.2
Stomach TGBC11TKB 9.2
Thyroid 8305C 8.3
Thyroid 8505C 7.8
Thyroid BCPAP 9
Thyroid BHT101 8.2
Thyroid CAL62 8.6
Thyroid CGTHW1 8.2
Thyroid FTC133 7.4
Thyroid FTC238 7.5
Thyroid ML1 8.3
Thyroid SW579 7.9
Thyroid TT2609C02 7.6
Thyroid TT 7.7
Upper aerodigestive tract BHY 9.3
Upper aerodigestive tract BICR16 8
Upper aerodigestive tract BICR18 7.2
Upper aerodigestive tract BICR22 8.3
Upper aerodigestive tract BICR31 8.4
Upper aerodigestive tract BICR56 8.7
Upper aerodigestive tract BICR6 8.1
Upper aerodigestive tract CAL27 8.4
Upper aerodigestive tract CAL33 8.6
Upper aerodigestive tract DETROIT562 8.3
Upper aerodigestive tract FADU 8.4
Upper aerodigestive tract HS840T 7.6
Upper aerodigestive tract HSC2 7.7
Upper aerodigestive tract HSC3 7.3
Upper aerodigestive tract HSC4 8.3
Upper aerodigestive tract PECAPJ15 8.1
Upper aerodigestive tract PECAPJ34CLONEC12 8.1
Upper aerodigestive tract PECAPJ41CLONED2 8.2
Upper aerodigestive tract PECAPJ49 7.7
Upper aerodigestive tract SCC15 8.6
Upper aerodigestive tract SCC25 7.9
Upper aerodigestive tract SCC4 8
Upper aerodigestive tract SCC9 7.6
Upper aerodigestive tract SNU1076 8.8
Upper aerodigestive tract SNU1214 8.8
Upper aerodigestive tract SNU46 7.8
Upper aerodigestive tract SNU899 8.5
Upper aerodigestive tract YD10B 8.8
Upper aerodigestive tract YD38 8.4
Upper aerodigestive tract YD8 8
Urinary tract 5637 7.4
Urinary tract 639V 7.8
Urinary tract 647V 7.6
Urinary tract BC3C 7.7
Urinary tract BFTC905 8.4
Urinary tract CAL29 8.2
Urinary tract HS172T 7.5
Urinary tract HT1197 8.6
Urinary tract HT1376 7.2
Urinary tract J82 7.1
Urinary tract JMSU1 7
Urinary tract KMBC2 8.8
Urinary tract KU1919 8.4
Urinary tract RT11284 8.2
Urinary tract RT112 8
Urinary tract RT4 8.4
Urinary tract SCABER 7.6
Urinary tract SW1710 7.4
Urinary tract SW780 8.6
Urinary tract T24 8.1
Urinary tract TCCSUP 8.1
Urinary tract UMUC1 7.8
Urinary tract UMUC3 6.7
Urinary tract VMCUB1 9.6
> The Human Protein Atlas (HPA)
 


Tissue Expression Level (TPM)
Adipose tissue 17
Adrenal gland 17.4
Appendix 30.9
Bone marrow 56
Breast 28.1
Cerebral cortex 31.1
Cervix, uterine 24.5
Colon 15.3
Duodenum 17.3
Endometrium 34.4
Epididymis 36.7
Esophagus 15.2
Fallopian tube 27
Gallbladder 27.8
Heart muscle 8.2
Kidney 17.7
Liver 8.5
Lung 25.4
Lymph node 33.3
Ovary 31.8
Pancreas 4.5
Parathyroid gland 41.8
Placenta 30.8
Prostate 33.4
Rectum 18.5
Salivary gland 9.7
Seminal vesicle 20.3
Skeletal muscle 13.6
Skin 25.6
Small intestine 19.9
Smooth muscle 21.5
Spleen 35.5
Stomach 18.7
Testis 40.2
Thyroid gland 46.8
Tonsil 25.4
Urinary bladder 17.3
> Text Mining based Expression
 
There is no record.
Summary
SymbolCHD2
Namechromodomain helicase DNA binding protein 2
Aliases FLJ38614; DKFZp547I1315; DKFZp781D1727; DKFZp686E01200; EEOC; ATP-dependent helicase CHD2; CHD-2; Chromodoma ......
Location15q26.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Somatic copy number alteration in primary tomur tissue
> The Cancer Genome Atlas (TCGA)
 


  Correlation between expression and SCNA as well as percentage of patients in different status.
Cancer Full Name # Sample R P % Loss % Neutral % Gain Status
BLCABladder urothelial carcinoma4040.3131.2e-1034.753.212.1Loss
BRCABreast invasive carcinoma10750.2991.07e-2324.558.517Neutral
CESCCervical and endocervical cancers2920.337.26e-0915.459.225.3Neutral
COADColon adenocarcinoma4490.3381.86e-1333.461.25.3Loss
ESCAEsophageal carcinoma1830.3741.85e-0724.645.929.5Neutral
GBMGlioblastoma multiforme1470.1410.08761973.57.5Neutral
HNSCHead and Neck squamous cell carcinoma5140.2422.68e-0819.162.618.3Neutral
KIRCKidney renal clear cell carcinoma5250.0980.02486.9885.1Neutral
KIRPKidney renal papillary cell carcinoma2880.0660.26410.887.51.7Neutral
LAMLAcute Myeloid Leukemia1660.0130.8652.497.60Neutral
LGGBrain Lower Grade Glioma5130.2631.37e-0910.386.53.1Neutral
LIHCLiver hepatocellular carcinoma3640.3621.03e-1220.665.913.5Neutral
LUADLung adenocarcinoma5120.2149.8e-0740.445.514.1Loss
LUSCLung squamous cell carcinoma4980.150.0008119.746.833.5Gain
OVOvarian serous cystadenocarcinoma3000.3495.07e-10413623Loss
PAADPancreatic adenocarcinoma1770.270.00027815.872.311.9Neutral
PCPGPheochromocytoma and Paraganglioma1620.1140.1492.589.58Neutral
PRADProstate adenocarcinoma4910.1882.82e-057.989.62.4Neutral
READRectum adenocarcinoma1640.170.029637.854.97.3Loss
SARCSarcoma2550.3527.42e-0915.75133.3Neutral
SKCMSkin Cutaneous Melanoma3670.2548.39e-0710.456.733Neutral
STADStomach adenocarcinoma4130.3753.02e-1516.56122.5Neutral
TGCTTesticular Germ Cell Tumors1500.4431.36e-0821.34632.7Neutral
THCAThyroid carcinoma4970.2188.86e-071.698.40Neutral
THYMThymoma1190.160.08131.788.210.1Neutral
UCECUterine Corpus Endometrial Carcinoma5370.2251.42e-0717.375.67.1Neutral
Summary
SymbolCHD2
Namechromodomain helicase DNA binding protein 2
Aliases FLJ38614; DKFZp547I1315; DKFZp781D1727; DKFZp686E01200; EEOC; ATP-dependent helicase CHD2; CHD-2; Chromodoma ......
Location15q26.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Methylation level in the promoter region of CR
> Methylation level in the promoter region of CR
 


  Correlation between expression and methylation as well as differential methylation analysis.
Cancer Full Name R P # N # T Delta beta (T vs N) P value (T vs N) Status
BLCABladder urothelial carcinoma-0.2262.56e-0617408-0.0811.53e-15NS/NA
BRCABreast invasive carcinoma-0.1365.97e-05837850.0012.48e-07NS/NA
CESCCervical and endocervical cancers-0.1130.04813306NANANS/NA
COADColon adenocarcinoma0.0230.679192970.0020.0203NS/NA
ESCAEsophageal carcinoma-0.2390.0008129185NANANS/NA
GBMGlioblastoma multiforme-0.1230.328164NANANS/NA
HNSCHead and Neck squamous cell carcinoma-0.1410.00101205220.0036.74e-07NS/NA
KIRCKidney renal clear cell carcinoma-0.040.4624319-0.0020.117NS/NA
KIRPKidney renal papillary cell carcinoma-0.1590.00606232750.0020.000418NS/NA
LAMLAcute Myeloid Leukemia-0.170.02670170NANANS/NA
LGGBrain Lower Grade Glioma-0.0830.05590530NANANS/NA
LIHCLiver hepatocellular carcinoma-0.140.00441413730.0083.39e-10NS/NA
LUADLung adenocarcinoma-0.2465.72e-0821456-0.0429.82e-16NS/NA
LUSCLung squamous cell carcinoma-0.0540.2968370NANANS/NA
OVOvarian serous cystadenocarcinoma-0.0170.98209NANANS/NA
PAADPancreatic adenocarcinoma-0.1570.03364179NANANS/NA
PCPGPheochromocytoma and Paraganglioma-0.3324.04e-063184NANANS/NA
PRADProstate adenocarcinoma-0.1240.00429354980.0053.48e-17NS/NA
READRectum adenocarcinoma-0.1960.0493299NANANS/NA
SARCSarcoma0.0840.1760263NANANS/NA
SKCMSkin Cutaneous Melanoma-0.1050.02291471NANANS/NA
STADStomach adenocarcinoma-0.0510.3230372NANANS/NA
TGCTTesticular Germ Cell Tumors-0.4283.49e-080156NANANS/NA
THCAThyroid carcinoma-0.0510.22650509-0.0010.266NS/NA
THYMThymoma-0.3479.86e-052120NANANS/NA
UCECUterine Corpus Endometrial Carcinoma-0.0910.050734431-0.0615.63e-10NS/NA
Summary
SymbolCHD2
Namechromodomain helicase DNA binding protein 2
Aliases FLJ38614; DKFZp547I1315; DKFZp781D1727; DKFZp686E01200; EEOC; ATP-dependent helicase CHD2; CHD-2; Chromodoma ......
Location15q26.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Primary tumor tissue from TCGA
> Normal tumor tissue from HPA
>The Cancer Genome Atlas (TCGA)
 
There is no record.
> The Human Protein Atlas (HPA)
 


Tissue Level Level Name
Adrenal gland 2 Medium
Appendix 1 Low
Bone marrow 2 Medium
Breast 1 Low
Bronchus 1 Low
Caudate 2 Medium
Cerebellum 3 High
Cerebral cortex 3 High
Cervix, uterine 2 Medium
Colon 2 Medium
Duodenum 2 Medium
Endometrium 3 High
Epididymis 3 High
Esophagus 1 Low
Fallopian tube 2 Medium
Gallbladder 2 Medium
Heart muscle 1 Low
Hippocampus 3 High
Kidney 2 Medium
Liver 2 Medium
Lung 2 Medium
Lymph node 2 Medium
Nasopharynx 2 Medium
Oral mucosa 2 Medium
Ovary 2 Medium
Pancreas 2 Medium
Parathyroid gland 2 Medium
Placenta 2 Medium
Prostate 2 Medium
Rectum 2 Medium
Salivary gland 1 Low
Seminal vesicle 3 High
Skeletal muscle 0 Not detected
Skin 1 Low
Small intestine 2 Medium
Smooth muscle 1 Low
Soft tissue 2 Medium
Spleen 1 Low
Stomach 2 Medium
Testis 3 High
Thyroid gland 2 Medium
Tonsil 2 Medium
Urinary bladder 2 Medium
Vagina 1 Low
Summary
SymbolCHD2
Namechromodomain helicase DNA binding protein 2
Aliases FLJ38614; DKFZp547I1315; DKFZp781D1727; DKFZp686E01200; EEOC; ATP-dependent helicase CHD2; CHD-2; Chromodoma ......
Location15q26.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Association between expresson and subtype
> Overall survival analysis based on expression
> Association between expresson and stage
> Association between expresson and grade
> Subtype
 


  Association between expresson and subtype.
Cancer Full Name # Patients P Value (Kruskal-Wallis) Association Source
BLCABladder urothelial carcinoma1280.385NS24476821
BRCABreast invasive carcinoma5210.00781Significant23000897
COADColon adenocarcinoma1490.48NS22810696
GBMGlioblastoma multiforme1570.00321Significant26824661
HNSCHead and Neck squamous cell carcinoma2790.0357Significant25631445
KIRPKidney renal papillary cell carcinoma1610.152NS26536169
LGGBrain Lower Grade Glioma5133.25e-15Significant26824661
LUADLung adenocarcinoma2300.000659Significant25079552
LUSCLung squamous cell carcinoma1780.926NS22960745
OVOvarian serous cystadenocarcinoma2870.00303Significant21720365
PRADProstate adenocarcinoma3331.23e-05Significant26544944
READRectum adenocarcinoma670.136NS22810696
SKCMSkin Cutaneous Melanoma3150.0329Significant26091043
STADStomach adenocarcinoma2770.605NS25079317
THCAThyroid carcinoma3911.34e-06Significant25417114
UCECUterine Corpus Endometrial Carcinoma2320.0457Significant23636398
> Overall survival
 

  Overall survival analysis based on expression.
Cancer Full Name # Patients Hazard Ratio P Value (Log Rank Test) Association
BLCABladder urothelial carcinoma405 0.8090.34NS
BRCABreast invasive carcinoma1079 0.8810.577NS
CESCCervical and endocervical cancers291 1.3230.406NS
COADColon adenocarcinoma439 1.7120.0729NS
ESCAEsophageal carcinoma184 1.3770.349NS
GBMGlioblastoma multiforme158 0.7670.301NS
HNSCHead and Neck squamous cell carcinoma518 0.9180.657NS
KIRCKidney renal clear cell carcinoma531 0.8450.455NS
KIRPKidney renal papillary cell carcinoma287 0.50.107NS
LAMLAcute Myeloid Leukemia149 0.8990.713NS
LGGBrain Lower Grade Glioma511 0.6420.0771NS
LIHCLiver hepatocellular carcinoma365 0.6720.115NS
LUADLung adenocarcinoma502 0.8870.565NS
LUSCLung squamous cell carcinoma494 1.0080.966NS
OVOvarian serous cystadenocarcinoma303 1.6550.0201Shorter
PAADPancreatic adenocarcinoma177 1.0610.844NS
PCPGPheochromocytoma and Paraganglioma179 00.265NS
PRADProstate adenocarcinoma497 1.10.893NS
READRectum adenocarcinoma159 1.1910.759NS
SARCSarcoma259 1.0180.949NS
SKCMSkin Cutaneous Melanoma459 0.7930.223NS
STADStomach adenocarcinoma388 0.6990.113NS
TGCTTesticular Germ Cell Tumors134 11NS
THCAThyroid carcinoma500 1.1480.838NS
THYMThymoma119 0.3250.306NS
UCECUterine Corpus Endometrial Carcinoma543 0.6190.115NS
> Stage
 

  Association between expresson and stage.
Cancer Full Name # Patients R Value (Spearman) P Value (Spearman) Association
BLCABladder urothelial carcinoma406 -0.0970.0516NS
BRCABreast invasive carcinoma1071 -0.0620.0424Lower
CESCCervical and endocervical cancers167 0.0050.946NS
COADColon adenocarcinoma445 0.0370.442NS
ESCAEsophageal carcinoma162 -0.0820.302NS
HNSCHead and Neck squamous cell carcinoma448 0.0360.446NS
KIRCKidney renal clear cell carcinoma531 -0.0460.289NS
KIRPKidney renal papillary cell carcinoma260 -0.0850.173NS
LIHCLiver hepatocellular carcinoma347 -0.0180.732NS
LUADLung adenocarcinoma507 -0.050.26NS
LUSCLung squamous cell carcinoma497 -0.0150.733NS
OVOvarian serous cystadenocarcinoma302 0.0340.557NS
PAADPancreatic adenocarcinoma176 0.0160.829NS
READRectum adenocarcinoma156 0.0640.431NS
SKCMSkin Cutaneous Melanoma410 -0.1350.00603Lower
STADStomach adenocarcinoma392 0.0770.128NS
TGCTTesticular Germ Cell Tumors81 -0.3270.0029Lower
THCAThyroid carcinoma499 -0.0570.203NS
UCECUterine Corpus Endometrial Carcinoma501 -0.070.118NS
> Grade
 

  Association between expresson and grade.
Cancer Full Name # Patients R Value (Spearman) P Value (Spearman) Association
CESCCervical and endocervical cancers272 -0.1350.0262Lower
HNSCHead and Neck squamous cell carcinoma498 -0.0560.212NS
KIRCKidney renal clear cell carcinoma525 -0.0860.0488Lower
LGGBrain Lower Grade Glioma514 -0.0690.119NS
LIHCLiver hepatocellular carcinoma366 -0.0510.333NS
OVOvarian serous cystadenocarcinoma296 0.1090.0603NS
PAADPancreatic adenocarcinoma176 -0.0740.326NS
STADStomach adenocarcinoma406 0.0040.939NS
UCECUterine Corpus Endometrial Carcinoma534 -0.0430.324NS
Summary
SymbolCHD2
Namechromodomain helicase DNA binding protein 2
Aliases FLJ38614; DKFZp547I1315; DKFZp781D1727; DKFZp686E01200; EEOC; ATP-dependent helicase CHD2; CHD-2; Chromodoma ......
Location15q26.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Targets inferred by reverse engineering method
> Targets identified by ChIP-seq data
> Targets inferred by reverse engineering method
 
> Targets identified by ChIP-seq data
 
Summary
SymbolCHD2
Namechromodomain helicase DNA binding protein 2
Aliases FLJ38614; DKFZp547I1315; DKFZp781D1727; DKFZp686E01200; EEOC; ATP-dependent helicase CHD2; CHD-2; Chromodoma ......
Location15q26.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Drugs from DrugBank database
> Drugs from DrugBank database
 
There is no record for CHD2.
Summary
SymbolCHD2
Namechromodomain helicase DNA binding protein 2
Aliases FLJ38614; DKFZp547I1315; DKFZp781D1727; DKFZp686E01200; EEOC; ATP-dependent helicase CHD2; CHD-2; Chromodoma ......
Location15q26.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Protein-Protein Interaction Network
> miRNA Regulatory Relationship
> Interactions from Text Mining
> Protein-Protein Interaction Network
 
> miRNA Regulatory Relationship
 
> Interactions from Text Mining
 
There is no record for CHD2.