CR2Cancer

Summary
Symbol	CHD6
Name	chromodomain helicase DNA binding protein 6
Aliases	KIAA1335; FLJ22369; dJ620E11.1; RIGB; CHD-6; ATP-dependent helicase CHD6; helicase C-terminal domain- and SN ......
Location	20q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

[ TOP ]

Domain

PF00385 Chromo (CHRromatin Organisation MOdifier) domain
PF00271 Helicase conserved C-terminal domain
PF00176 SNF2 family N-terminal domain

Function

Probable chromatin-remodeling protein with a DNA-dependent ATPase activity. May play a role in transcription regulation, activating for instance, the transcription of specific genes in response to oxidative stress through interaction with NFE2L2.

Classification

Class	Modification	Substrate	Product	PubMed
#	#	#	#	#

> Gene Ontology [ TOP ]
Biological Process	GO:0006979 response to oxidative stress GO:0034599 cellular response to oxidative stress GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress GO:0043620 regulation of DNA-templated transcription in response to stress GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
Molecular Function	GO:0001221 transcription cofactor binding GO:0004386 helicase activity GO:0008026 ATP-dependent helicase activity GO:0008094 DNA-dependent ATPase activity GO:0008134 transcription factor binding GO:0016887 ATPase activity GO:0042623 ATPase activity, coupled GO:0070035 purine NTP-dependent helicase activity
Cellular Component	GO:0000428 DNA-directed RNA polymerase complex GO:0005665 DNA-directed RNA polymerase II, core complex GO:0016591 DNA-directed RNA polymerase II, holoenzyme GO:0030880 RNA polymerase complex GO:0055029 nuclear DNA-directed RNA polymerase complex GO:0061695 transferase complex, transferring phosphorus-containing groups

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	-

Summary
Symbol	CHD6
Name	chromodomain helicase DNA binding protein 6
Aliases	KIAA1335; FLJ22369; dJ620E11.1; RIGB; CHD-6; ATP-dependent helicase CHD6; helicase C-terminal domain- and SN ......
Location	20q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM3707762	c.3784G>A	p.V1262I	Substitution - Missense	Liver
COSM5974050	c.685G>C	p.E229Q	Substitution - Missense	Upper_aerodigestive_tract
COSM1284108	c.2477A>G	p.Y826C	Substitution - Missense	Autonomic_ganglia
COSM3799546	c.6659C>G	p.S2220C	Substitution - Missense	Urinary_tract
COSM1632297	c.3878-6G>C	p.?	Unknown	Liver
COSM254610	c.6481C>A	p.H2161N	Substitution - Missense	Urinary_tract
COSM4851872	c.719G>A	p.R240K	Substitution - Missense	Cervix
COSM1483641	c.3711C>A	p.Y1237*	Substitution - Nonsense	Breast
COSM3423650	c.5540T>G	p.L1847*	Substitution - Nonsense	Large_intestine
COSM4543754	c.3439G>A	p.G1147R	Substitution - Missense	Skin
COSM4792947	c.1308G>A	p.K436K	Substitution - coding silent	Liver
COSM1713476	c.3295C>T	p.R1099W	Substitution - Missense	Small_intestine
COSM4098438	c.6929C>T	p.A2310V	Substitution - Missense	Stomach
COSM4571516	c.4788T>C	p.T1596T	Substitution - coding silent	Skin
COSM4966980	c.3705G>A	p.M1235I	Substitution - Missense	Central_nervous_system
COSM3770797	c.5477T>C	p.M1826T	Substitution - Missense	Pancreas
COSM1483637	c.6813G>A	p.Q2271Q	Substitution - coding silent	Breast
COSM3291648	c.6381C>T	p.T2127T	Substitution - coding silent	Large_intestine
COSM1681679	c.7381C>T	p.P2461S	Substitution - Missense	Large_intestine
COSM1615602	c.1310A>G	p.H437R	Substitution - Missense	Liver
COSM4098448	c.5851G>A	p.E1951K	Substitution - Missense	Stomach
COSM4166626	c.2527G>A	p.D843N	Substitution - Missense	Pituitary
COSM1026839	c.7999T>C	p.S2667P	Substitution - Missense	Endometrium
COSM4098470	c.1175G>T	p.G392V	Substitution - Missense	Stomach
COSM4672071	c.2870G>A	p.R957Q	Substitution - Missense	Large_intestine
COSM77463	c.3272G>A	p.R1091H	Substitution - Missense	Stomach
COSM1615600	c.1962T>G	p.A654A	Substitution - coding silent	Liver
COSM4653286	c.6653A>G	p.D2218G	Substitution - Missense	Large_intestine
COSM159980	c.449G>A	p.G150E	Substitution - Missense	Breast
COSM4098447	c.5891T>G	p.I1964S	Substitution - Missense	Stomach
COSM5606430	c.4316T>G	p.M1439R	Substitution - Missense	Skin
COSM3546358	c.5059C>T	p.Q1687*	Substitution - Nonsense	Skin
COSM1483642	c.1461G>C	p.E487D	Substitution - Missense	Breast
COSM5508649	c.6304G>C	p.D2102H	Substitution - Missense	Biliary_tract
COSM1592600	c.5112G>T	p.E1704D	Substitution - Missense	Endometrium
COSM1026842	c.7652C>T	p.P2551L	Substitution - Missense	Large_intestine
COSM4608919	c.3219C>A	p.S1073R	Substitution - Missense	Adrenal_gland
COSM5806204	c.2531G>T	p.R844L	Substitution - Missense	Liver
COSM82065	c.7074G>C	p.L2358L	Substitution - coding silent	Ovary
COSM3740136	c.4192C>G	p.L1398V	Substitution - Missense	Liver
COSM5606430	c.4316T>G	p.M1439R	Substitution - Missense	Skin
COSM2155611	c.5495G>A	p.C1832Y	Substitution - Missense	Central_nervous_system
COSM5392066	c.619G>A	p.V207M	Substitution - Missense	Skin
COSM4463557	c.1297C>T	p.P433S	Substitution - Missense	Liver
COSM106635	c.1545C>T	p.I515I	Substitution - coding silent	Skin
COSM1179714	c.2742G>A	p.E914E	Substitution - coding silent	Prostate
COSM369308	c.5794G>T	p.A1932S	Substitution - Missense	Lung
COSM1026862	c.4449C>A	p.I1483I	Substitution - coding silent	Endometrium
COSM219271	c.2037G>A	p.M679I	Substitution - Missense	Breast
COSM1615601	c.1837G>C	p.G613R	Substitution - Missense	Liver
COSM4413278	c.2006A>T	p.K669M	Substitution - Missense	Oesophagus
COSM4672078	c.644G>T	p.G215V	Substitution - Missense	Large_intestine
COSM5726473	c.5660G>A	p.R1887K	Substitution - Missense	Skin
COSM1026860	c.4759G>A	p.G1587S	Substitution - Missense	Endometrium
COSM5707444	c.2057A>T	p.D686V	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1026863	c.4419G>T	p.K1473N	Substitution - Missense	Endometrium
COSM4845058	c.2463G>A	p.Q821Q	Substitution - coding silent	Cervix
COSM5029430	c.550G>T	p.A184S	Substitution - Missense	Bone
COSM4098454	c.3419A>G	p.Y1140C	Substitution - Missense	Stomach
COSM3546367	c.3336G>A	p.W1112*	Substitution - Nonsense	Skin
COSM1411839	c.2500C>T	p.R834W	Substitution - Missense	Large_intestine
COSM3546350	c.7623C>T	p.P2541P	Substitution - coding silent	Skin
COSM4540000	c.276G>A	p.V92V	Substitution - coding silent	Skin
COSM1026870	c.3664C>A	p.L1222I	Substitution - Missense	Endometrium
COSM1411851	c.549G>A	p.K183K	Substitution - coding silent	Large_intestine
COSM5057312	c.5102A>C	p.E1701A	Substitution - Missense	Stomach
COSM4581815	c.7808C>G	p.T2603S	Substitution - Missense	Bone
COSM3841017	c.6046G>A	p.E2016K	Substitution - Missense	Breast
COSM3713309	c.1028G>A	p.R343H	Substitution - Missense	Upper_aerodigestive_tract
COSM5927889	c.7817C>T	p.P2606L	Substitution - Missense	Skin
COSM6004399	c.3403C>T	p.R1135C	Substitution - Missense	Prostate
COSM13857	c.5860G>A	p.E1954K	Substitution - Missense	Lung
COSM443834	c.6409C>T	p.R2137*	Substitution - Nonsense	Lung
COSM319435	c.1088C>T	p.T363M	Substitution - Missense	Lung
COSM5057311	c.6598A>G	p.T2200A	Substitution - Missense	Stomach
COSM4098449	c.5714A>G	p.N1905S	Substitution - Missense	Stomach
COSM3291624	c.8066G>A	p.S2689N	Substitution - Missense	Large_intestine
COSM1307400	c.5992G>C	p.E1998Q	Substitution - Missense	Urinary_tract
COSM3291747	c.848C>T	p.A283V	Substitution - Missense	Stomach
COSM3291653	c.6104G>C	p.R2035T	Substitution - Missense	Large_intestine
COSM4098442	c.6473C>T	p.A2158V	Substitution - Missense	Stomach
COSM3291688	c.3745G>C	p.E1249Q	Substitution - Missense	Upper_aerodigestive_tract
COSM1615599	c.1975T>C	p.F659L	Substitution - Missense	Liver
COSM1200991	c.4783C>T	p.R1595C	Substitution - Missense	Large_intestine
COSM4567491	c.7360_7361CC>TT	p.P2454F	Substitution - Missense	Skin
COSM3291641	c.6860G>A	p.R2287Q	Substitution - Missense	Skin
COSM3546362	c.4232A>G	p.K1411R	Substitution - Missense	Skin
COSM3546353	c.7470C>T	p.I2490I	Substitution - coding silent	Breast
COSM1615600	c.1962T>G	p.A654A	Substitution - coding silent	Liver
COSM1026849	c.6472G>A	p.A2158T	Substitution - Missense	Liver
COSM1483639	c.5670A>C	p.V1890V	Substitution - coding silent	Breast
COSM5476169	c.1232C>T	p.T411M	Substitution - Missense	Large_intestine
COSM4098443	c.6325T>G	p.L2109V	Substitution - Missense	Stomach
COSM4401342	c.2215A>C	p.M739L	Substitution - Missense	Skin
COSM3546370	c.2672C>A	p.A891D	Substitution - Missense	Skin
COSM4424890	c.2483G>A	p.R828Q	Substitution - Missense	Oesophagus
COSM6004501	c.4792T>C	p.C1598R	Substitution - Missense	Prostate
COSM3546366	c.3541C>T	p.P1181S	Substitution - Missense	Skin
COSM1483638	c.5770C>T	p.P1924S	Substitution - Missense	Breast
COSM1026869	c.3694C>T	p.R1232*	Substitution - Nonsense	Endometrium
COSM5109392	c.7656G>A	p.A2552A	Substitution - coding silent	Oesophagus
COSM3291704	c.2854G>T	p.V952L	Substitution - Missense	Large_intestine
COSM4970314	c.7132-7A>G	p.?	Unknown	Central_nervous_system
COSM224037	c.928G>A	p.E310K	Substitution - Missense	Skin
COSM3546364	c.4076C>T	p.S1359F	Substitution - Missense	Skin
COSM268490	c.1981G>A	p.D661N	Substitution - Missense	Large_intestine
COSM1179656	c.7486G>A	p.V2496M	Substitution - Missense	Prostate
COSM5678212	c.6004G>T	p.E2002*	Substitution - Nonsense	Soft_tissue
COSM3423653	c.651G>T	p.T217T	Substitution - coding silent	Kidney
COSM2155978	c.2032A>G	p.M678V	Substitution - Missense	Central_nervous_system
COSM1681678	c.7405A>T	p.M2469L	Substitution - Missense	Kidney
COSM390183	c.6148G>A	p.E2050K	Substitution - Missense	Lung
COSM5894071	c.7360C>T	p.P2454S	Substitution - Missense	Skin
COSM254612	c.1864A>T	p.K622*	Substitution - Nonsense	Urinary_tract
COSM3291624	c.8066G>A	p.S2689N	Substitution - Missense	Large_intestine
COSM1026875	c.2745C>T	p.R915R	Substitution - coding silent	Endometrium
COSM279874	c.5468T>G	p.F1823C	Substitution - Missense	Large_intestine
COSM5343593	c.7488G>A	p.V2496V	Substitution - coding silent	Large_intestine
COSM6004501	c.4792T>C	p.C1598R	Substitution - Missense	Prostate
COSM3291676	c.4199G>A	p.R1400H	Substitution - Missense	Large_intestine
COSM4969946	c.6082G>T	p.E2028*	Substitution - Nonsense	Central_nervous_system
COSM3291628	c.7685C>T	p.T2562M	Substitution - Missense	Kidney
COSM4608918	c.6894G>T	p.M2298I	Substitution - Missense	Adrenal_gland
COSM1411835	c.4600C>T	p.R1534C	Substitution - Missense	Large_intestine
COSM5930005	c.6430G>A	p.E2144K	Substitution - Missense	Skin
COSM3740137	c.2661G>A	p.L887L	Substitution - coding silent	Liver
COSM5974048	c.5538T>C	p.D1846D	Substitution - coding silent	Upper_aerodigestive_tract
COSM1681682	c.2709G>T	p.K903N	Substitution - Missense	Large_intestine
COSM5343594	c.430G>A	p.E144K	Substitution - Missense	Large_intestine
COSM1661127	c.7669A>T	p.T2557S	Substitution - Missense	Kidney
COSM385468	c.2083C>G	p.Q695E	Substitution - Missense	Lung
COSM1026853	c.5224G>T	p.D1742Y	Substitution - Missense	Endometrium
COSM1026882	c.970A>C	p.N324H	Substitution - Missense	Endometrium
COSM3291676	c.4199G>A	p.R1400H	Substitution - Missense	Liver
COSM3991700	c.7614C>T	p.L2538L	Substitution - coding silent	Kidney
COSM5911055	c.1487C>T	p.S496F	Substitution - Missense	Skin
COSM3799547	c.5686C>A	p.P1896T	Substitution - Missense	Urinary_tract
COSM1130633	c.86A>G	p.N29S	Substitution - Missense	Prostate
COSM1615599	c.1975T>C	p.F659L	Substitution - Missense	Liver
COSM1757009	c.7533C>T	p.V2511V	Substitution - coding silent	Urinary_tract
COSM4581818	c.3531T>C	p.S1177S	Substitution - coding silent	Bone
COSM3371680	c.7409A>G	p.N2470S	Substitution - Missense	Thyroid
COSM4996022	c.3117A>T	p.E1039D	Substitution - Missense	Upper_aerodigestive_tract
COSM5516089	c.5391G>C	p.Q1797H	Substitution - Missense	Biliary_tract
COSM159981	c.1440A>T	p.K480N	Substitution - Missense	Breast
COSM254614	c.64C>T	p.P22S	Substitution - Missense	Urinary_tract
COSM4800185	c.5495G>T	p.C1832F	Substitution - Missense	Liver
COSM1483643	c.689C>G	p.S230C	Substitution - Missense	Breast
COSM1026866	c.4164G>T	p.W1388C	Substitution - Missense	Endometrium
COSM3546372	c.2159C>T	p.S720F	Substitution - Missense	Skin
COSM4499144	c.5354C>T	p.S1785L	Substitution - Missense	Skin
COSM4792886	c.1306A>T	p.K436*	Substitution - Nonsense	Liver
COSM1026851	c.5992G>T	p.E1998*	Substitution - Nonsense	Endometrium
COSM3546373	c.1936C>T	p.P646S	Substitution - Missense	Skin
COSM4996021	c.5220C>A	p.S1740R	Substitution - Missense	Upper_aerodigestive_tract
COSM3693500	c.7097C>T	p.A2366V	Substitution - Missense	Large_intestine
COSM4619497	c.6649A>G	p.M2217V	Substitution - Missense	Large_intestine
COSM4672063	c.7900A>G	p.M2634V	Substitution - Missense	Large_intestine
COSM1411836	c.4143C>T	p.S1381S	Substitution - coding silent	Large_intestine
COSM1026843	c.7515G>A	p.M2505I	Substitution - Missense	Endometrium
COSM3423655	c.591G>T	p.K197N	Substitution - Missense	Large_intestine
COSM5904040	c.5591G>A	p.S1864N	Substitution - Missense	Skin
COSM4655803	c.8041G>A	p.G2681S	Substitution - Missense	Large_intestine
COSM3291685	c.3843C>T	p.A1281A	Substitution - coding silent	Skin
COSM5894690	c.7589A>C	p.Q2530P	Substitution - Missense	Skin
COSM3740138	c.295A>G	p.K99E	Substitution - Missense	Liver
COSM347976	c.2674C>T	p.R892*	Substitution - Nonsense	Lung
COSM5577341	c.3534C>T	p.A1178A	Substitution - coding silent	Skin
COSM3291759	c.714G>A	p.S238S	Substitution - coding silent	Liver
COSM1307404	c.4939C>G	p.Q1647E	Substitution - Missense	Urinary_tract
COSM3911311	c.7060C>T	p.P2354S	Substitution - Missense	Skin
COSM292383	c.2847A>G	p.K949K	Substitution - coding silent	Large_intestine
COSM5392062	c.7158G>A	p.R2386R	Substitution - coding silent	Skin
COSM4098450	c.5212T>C	p.S1738P	Substitution - Missense	Stomach
COSM4619497	c.6649A>G	p.M2217V	Substitution - Missense	Large_intestine
COSM4581816	c.6277A>T	p.K2093*	Substitution - Nonsense	Bone
COSM5555037	c.7424G>T	p.G2475V	Substitution - Missense	Prostate
COSM4411118	c.3284C>T	p.A1095V	Substitution - Missense	Kidney
COSM3405082	c.4058A>C	p.Q1353P	Substitution - Missense	Central_nervous_system
COSM4098461	c.2583G>A	p.A861A	Substitution - coding silent	Stomach
COSM3991701	c.4955C>T	p.S1652L	Substitution - Missense	Kidney
COSM5574258	c.451G>A	p.A151T	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1411823	c.8059G>A	p.E2687K	Substitution - Missense	Large_intestine
COSM4098435	c.7691T>C	p.V2564A	Substitution - Missense	Stomach
COSM5574492	c.409_410insCCG	p.K137>TE	Complex - insertion inframe	Haematopoietic_and_lymphoid_tissue
COSM1238499	c.4554C>T	p.G1518G	Substitution - coding silent	Oesophagus
COSM5451571	c.770A>G	p.D257G	Substitution - Missense	Large_intestine
COSM167796	c.3189C>T	p.D1063D	Substitution - coding silent	Stomach
COSM723656	c.4031A>T	p.N1344I	Substitution - Missense	Lung
COSM5574492	c.409_410insCCG	p.K137>TE	Complex - insertion inframe	Haematopoietic_and_lymphoid_tissue
COSM1411831	c.6255_6256delCT	p.Y2086fs*4	Deletion - Frameshift	Large_intestine
COSM5599298	c.7853C>T	p.S2618F	Substitution - Missense	Skin
COSM219272	c.2029C>G	p.P677A	Substitution - Missense	Breast
COSM5606430	c.4316T>G	p.M1439R	Substitution - Missense	Skin
COSM219271	c.2037G>A	p.M679I	Substitution - Missense	Breast
COSM6004399	c.3403C>T	p.R1135C	Substitution - Missense	Prostate
COSM1200989	c.6610A>G	p.T2204A	Substitution - Missense	Large_intestine
COSM254613	c.3404G>A	p.R1135H	Substitution - Missense	Lung
COSM5013602	c.4175C>T	p.S1392F	Substitution - Missense	Kidney
COSM4831779	c.6883G>A	p.E2295K	Substitution - Missense	Cervix
COSM1026874	c.2817C>T	p.G939G	Substitution - coding silent	Endometrium
COSM6006202	c.6866G>T	p.G2289V	Substitution - Missense	Small_intestine
COSM340168	c.4593T>G	p.T1531T	Substitution - coding silent	Lung
COSM1411822	c.8148G>T	p.*2716Y	Nonstop extension	Large_intestine
COSM4098451	c.4872G>T	p.Q1624H	Substitution - Missense	Stomach
COSM227395	c.242G>A	p.G81E	Substitution - Missense	Skin
COSM1193243	c.4603G>T	p.A1535S	Substitution - Missense	Lung
COSM1200992	c.4497T>G	p.F1499L	Substitution - Missense	Large_intestine
COSM4504561	c.6693C>T	p.S2231S	Substitution - coding silent	Skin
COSM6004501	c.4792T>C	p.C1598R	Substitution - Missense	Prostate
COSM1326738	c.5581C>T	p.Q1861*	Substitution - Nonsense	Ovary
COSM4934944	c.5978A>T	p.H1993L	Substitution - Missense	Liver
COSM3841021	c.1831C>T	p.L611L	Substitution - coding silent	Breast
COSM13857	c.5860G>A	p.E1954K	Substitution - Missense	Lung
COSM70169	c.1319G>A	p.R440Q	Substitution - Missense	Ovary
COSM39950	c.806G>A	p.G269D	Substitution - Missense	Central_nervous_system
COSM723657	c.4455C>T	p.S1485S	Substitution - coding silent	Lung
COSM3546378	c.830C>T	p.S277F	Substitution - Missense	Skin
COSM1641346	c.3148G>T	p.V1050L	Substitution - Missense	Stomach
COSM1615603	c.603G>A	p.R201R	Substitution - coding silent	Liver
COSM266239	c.956A>G	p.Y319C	Substitution - Missense	Large_intestine
COSM5599298	c.7853C>T	p.S2618F	Substitution - Missense	Skin
COSM5894071	c.7360C>T	p.P2454S	Substitution - Missense	Skin
COSM3423653	c.651G>T	p.T217T	Substitution - coding silent	Large_intestine
COSM1026849	c.6472G>A	p.A2158T	Substitution - Missense	Endometrium
COSM1726402	c.6835A>G	p.R2279G	Substitution - Missense	Liver
COSM219272	c.2029C>G	p.P677A	Substitution - Missense	Breast
COSM1741899	c.475G>A	p.E159K	Substitution - Missense	Urinary_tract
COSM1713478	c.2729G>A	p.R910Q	Substitution - Missense	Skin
COSM4136893	c.1049G>C	p.R350P	Substitution - Missense	Ovary
COSM5759977	c.4485G>A	p.L1495L	Substitution - coding silent	Bone
COSM3546361	c.4454C>T	p.S1485F	Substitution - Missense	Skin
COSM4450369	c.5656delG	p.E1886fs*32	Deletion - Frameshift	Skin
COSM266238	c.1714G>A	p.V572I	Substitution - Missense	Large_intestine
COSM4792886	c.1306A>T	p.K436*	Substitution - Nonsense	Liver
COSM310083	c.2563T>C	p.F855L	Substitution - Missense	Soft_tissue
COSM4098468	c.1359C>T	p.R453R	Substitution - coding silent	Stomach
COSM1411828	c.7340G>A	p.R2447Q	Substitution - Missense	Large_intestine
COSM1026844	c.7511C>T	p.T2504M	Substitution - Missense	Endometrium
COSM5941426	c.2143C>T	p.L715F	Substitution - Missense	Skin
COSM577388	c.5743G>T	p.G1915*	Substitution - Nonsense	Large_intestine
COSM4098446	c.5919T>G	p.N1973K	Substitution - Missense	Stomach
COSM3799548	c.4384G>A	p.V1462M	Substitution - Missense	Urinary_tract
COSM1026872	c.3219C>T	p.S1073S	Substitution - coding silent	Endometrium
COSM5033771	c.633G>C	p.E211D	Substitution - Missense	Skin
COSM3799550	c.1529G>T	p.G510V	Substitution - Missense	Urinary_tract
COSM4753409	c.401A>T	p.K134M	Substitution - Missense	Stomach
COSM5392063	c.6984C>G	p.H2328Q	Substitution - Missense	Skin
COSM13856	c.6679C>T	p.P2227S	Substitution - Missense	Skin
COSM254614	c.64C>T	p.P22S	Substitution - Missense	Urinary_tract
COSM1307399	c.7010C>T	p.S2337L	Substitution - Missense	Urinary_tract
COSM4506827	c.7303C>T	p.R2435*	Substitution - Nonsense	Skin
COSM5923353	c.4837A>G	p.R1613G	Substitution - Missense	Skin
COSM1026881	c.973T>G	p.F325V	Substitution - Missense	Large_intestine
COSM5434422	c.2067G>C	p.K689N	Substitution - Missense	Oesophagus
COSM3291661	c.5462G>T	p.S1821I	Substitution - Missense	Large_intestine
COSM4098433	c.7857T>G	p.P2619P	Substitution - coding silent	Stomach
COSM3963571	c.1994A>G	p.E665G	Substitution - Missense	Lung
COSM1026883	c.205G>A	p.A69T	Substitution - Missense	Endometrium
COSM149175	c.7453A>G	p.R2485G	Substitution - Missense	Stomach
COSM254608	c.4126G>T	p.A1376S	Substitution - Missense	Urinary_tract
COSM3546372	c.2159C>T	p.S720F	Substitution - Missense	Skin
COSM5673662	c.939C>T	p.F313F	Substitution - coding silent	Soft_tissue
COSM1713475	c.7985G>A	p.G2662E	Substitution - Missense	Liver
COSM4536093	c.2268G>A	p.E756E	Substitution - coding silent	Skin
COSM4823388	c.6215G>A	p.R2072Q	Substitution - Missense	Cervix
COSM1248217	c.7707G>A	p.A2569A	Substitution - coding silent	Oesophagus
COSM1026859	c.4887C>A	p.L1629L	Substitution - coding silent	Endometrium
COSM1200993	c.1083T>G	p.I361M	Substitution - Missense	Large_intestine
COSM3546351	c.7619C>T	p.P2540L	Substitution - Missense	Skin
COSM1495085	c.5487T>C	p.L1829L	Substitution - coding silent	Kidney
COSM254613	c.3404G>A	p.R1135H	Substitution - Missense	Skin
COSM1026850	c.6240A>G	p.L2080L	Substitution - coding silent	Endometrium
COSM3758571	c.7284T>C	p.T2428T	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM74135	c.3865G>A	p.V1289M	Substitution - Missense	Large_intestine
COSM1326737	c.3228C>T	p.D1076D	Substitution - coding silent	Ovary
COSM723655	c.3887G>A	p.R1296K	Substitution - Missense	Lung
COSM3291622	c.8079C>T	p.P2693P	Substitution - coding silent	Liver
COSM4518644	c.7322_7323GG>AA	p.R2441K	Substitution - Missense	Skin
COSM4912100	c.6118C>T	p.H2040Y	Substitution - Missense	Liver
COSM5549107	c.6460G>A	p.A2154T	Substitution - Missense	Prostate
COSM3841024	c.882T>G	p.I294M	Substitution - Missense	Breast
COSM1615603	c.603G>A	p.R201R	Substitution - coding silent	Liver
COSM4098448	c.5851G>A	p.E1951K	Substitution - Missense	Oesophagus
COSM4961602	c.4952C>A	p.T1651N	Substitution - Missense	Pancreas
COSM13856	c.6679C>T	p.P2227S	Substitution - Missense	Skin
COSM3546380	c.802G>A	p.A268T	Substitution - Missense	Skin
COSM107968	c.6221C>T	p.P2074L	Substitution - Missense	Skin
COSM1411846	c.1383C>T	p.L461L	Substitution - coding silent	Large_intestine
COSM1196472	c.7213G>C	p.E2405Q	Substitution - Missense	Lung
COSM5430017	c.7203G>A	p.L2401L	Substitution - coding silent	Oesophagus
COSM337080	c.980A>C	p.Y327S	Substitution - Missense	Lung
COSM4391528	c.7560G>C	p.M2520I	Substitution - Missense	Breast
COSM119985	c.2845A>G	p.K949E	Substitution - Missense	Ovary
COSM1026867	c.3935T>A	p.V1312D	Substitution - Missense	Endometrium
COSM3423649	c.6214C>T	p.R2072*	Substitution - Nonsense	Large_intestine
COSM5741885	c.1968G>T	p.L656F	Substitution - Missense	Small_intestine
COSM4959295	c.2002-1G>A	p.?	Unknown	Liver
COSM3546355	c.7316C>T	p.P2439L	Substitution - Missense	Skin
COSM159982	c.133G>A	p.E45K	Substitution - Missense	Breast
COSM107349	c.4402G>T	p.V1468F	Substitution - Missense	Skin
COSM271165	c.647T>C	p.L216P	Substitution - Missense	Large_intestine
COSM3799549	c.3558G>A	p.G1186G	Substitution - coding silent	Urinary_tract
COSM5748168	c.95A>G	p.Y32C	Substitution - Missense	Pancreas
COSM3405080	c.6810A>G	p.G2270G	Substitution - coding silent	Central_nervous_system
COSM1411825	c.7718C>T	p.P2573L	Substitution - Missense	Large_intestine
COSM5909819	c.5792C>T	p.P1931L	Substitution - Missense	Skin
COSM5744414	c.723A>T	p.Q241H	Substitution - Missense	Small_intestine
COSM4672068	c.5619C>T	p.N1873N	Substitution - coding silent	Large_intestine
COSM5392064	c.6002A>G	p.K2001R	Substitution - Missense	Skin
COSM443840	c.402G>T	p.K134N	Substitution - Missense	Breast
COSM443836	c.3240G>A	p.T1080T	Substitution - coding silent	Skin
COSM1411844	c.2038C>T	p.L680F	Substitution - Missense	Large_intestine
COSM5655345	c.5097G>T	p.L1699L	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM723660	c.6860G>T	p.R2287L	Substitution - Missense	Lung
COSM1026868	c.3838G>A	p.E1280K	Substitution - Missense	Endometrium
COSM1248218	c.4472C>T	p.S1491L	Substitution - Missense	Oesophagus
COSM459747	c.7753G>A	p.E2585K	Substitution - Missense	Cervix
COSM4830536	c.7248G>A	p.L2416L	Substitution - coding silent	Cervix
COSM4983810	c.6845C>T	p.A2282V	Substitution - Missense	Oesophagus
COSM106635	c.1545C>T	p.I515I	Substitution - coding silent	Skin
COSM1411834	c.4806C>T	p.N1602N	Substitution - coding silent	Large_intestine
COSM3389754	c.673G>A	p.E225K	Substitution - Missense	Pancreas
COSM4792947	c.1308G>A	p.K436K	Substitution - coding silent	Liver
COSM5767069	c.710G>A	p.R237H	Substitution - Missense	Breast
COSM239310	c.6383C>T	p.P2128L	Substitution - Missense	Prostate
COSM3291623	c.8076G>C	p.L2692F	Substitution - Missense	Large_intestine
COSM3546352	c.7495C>T	p.P2499S	Substitution - Missense	Skin
COSM5599298	c.7853C>T	p.S2618F	Substitution - Missense	Skin
COSM4098444	c.6013G>C	p.E2005Q	Substitution - Missense	Stomach
COSM5745443	c.1442_1443insA	p.N481fs*6	Insertion - Frameshift	Pancreas
COSM3758571	c.7284T>C	p.T2428T	Substitution - coding silent	Large_intestine
COSM5960188	c.3961_3962insT	p.S1321fs*15	Insertion - Frameshift	Thyroid
COSM4292012	c.65C>T	p.P22L	Substitution - Missense	Large_intestine
COSM1757010	c.4893C>T	p.C1631C	Substitution - coding silent	Urinary_tract
COSM82066	c.2361G>A	p.L787L	Substitution - coding silent	Ovary
COSM1737465	c.1387G>A	p.E463K	Substitution - Missense	Central_nervous_system
COSM254609	c.1717G>A	p.V573I	Substitution - Missense	Urinary_tract
COSM4640275	c.6709G>A	p.A2237T	Substitution - Missense	Large_intestine
COSM4098432	c.8091A>G	p.E2697E	Substitution - coding silent	Stomach
COSM3291633	c.7261C>T	p.P2421S	Substitution - Missense	Skin
COSM4925339	c.5522A>T	p.D1841V	Substitution - Missense	Liver
COSM3546353	c.7470C>T	p.I2490I	Substitution - coding silent	Skin
COSM3841020	c.2102T>G	p.V701G	Substitution - Missense	Breast
COSM4672062	c.8114G>T	p.G2705V	Substitution - Missense	Large_intestine
COSM1411842	c.2229G>T	p.K743N	Substitution - Missense	Large_intestine
COSM1026845	c.7480G>T	p.G2494W	Substitution - Missense	Endometrium
COSM159983	c.5229G>A	p.G1743G	Substitution - coding silent	Breast
COSM1411834	c.4806C>T	p.N1602N	Substitution - coding silent	Stomach
COSM1026840	c.7864A>G	p.I2622V	Substitution - Missense	Endometrium
COSM443835	c.4811C>G	p.P1604R	Substitution - Missense	Breast
COSM443838	c.1048C>T	p.R350*	Substitution - Nonsense	Breast
COSM3693501	c.3813G>A	p.E1271E	Substitution - coding silent	Large_intestine
COSM5449422	c.4457G>A	p.R1486H	Substitution - Missense	Large_intestine
COSM1200994	c.2428C>T	p.R810C	Substitution - Missense	Large_intestine
COSM4672075	c.1190A>G	p.H397R	Substitution - Missense	Large_intestine
COSM6004399	c.3403C>T	p.R1135C	Substitution - Missense	Prostate
COSM4440740	c.8064C>T	p.P2688P	Substitution - coding silent	Bone
COSM3363250	c.1971G>A	p.E657E	Substitution - coding silent	Kidney
COSM5822836	c.1943A>T	p.Q648L	Substitution - Missense	Liver
COSM3291690	c.3499G>A	p.A1167T	Substitution - Missense	Skin
COSM3291728	c.1704C>T	p.F568F	Substitution - coding silent	Large_intestine
COSM4389056	c.4105G>A	p.E1369K	Substitution - Missense	Pancreas
COSM478165	c.1010A>G	p.E337G	Substitution - Missense	Kidney
COSM254608	c.4126G>T	p.A1376S	Substitution - Missense	Urinary_tract
COSM4653287	c.3280C>T	p.R1094*	Substitution - Nonsense	Large_intestine
COSM254612	c.1864A>T	p.K622*	Substitution - Nonsense	Urinary_tract
COSM4098445	c.5928C>T	p.A1976A	Substitution - coding silent	Stomach
COSM1615599	c.1975T>C	p.F659L	Substitution - Missense	Liver
COSM4463557	c.1297C>T	p.P433S	Substitution - Missense	Skin
COSM1026858	c.4891T>C	p.C1631R	Substitution - Missense	Endometrium
COSM1026884	c.138G>T	p.E46D	Substitution - Missense	Endometrium
COSM443836	c.3240G>A	p.T1080T	Substitution - coding silent	Breast
COSM4753392	c.4250A>G	p.E1417G	Substitution - Missense	Stomach
COSM3291622	c.8079C>T	p.P2693P	Substitution - coding silent	Large_intestine
COSM389414	c.4564G>C	p.D1522H	Substitution - Missense	Lung
COSM4098460	c.2743C>T	p.R915C	Substitution - Missense	Stomach
COSM5819685	c.4015A>T	p.T1339S	Substitution - Missense	Liver
COSM239312	c.1546G>A	p.A516T	Substitution - Missense	Prostate
COSM1615599	c.1975T>C	p.F659L	Substitution - Missense	Liver
COSM253697	c.63C>A	p.S21S	Substitution - coding silent	Urinary_tract
COSM255445	c.1640A>C	p.Q547P	Substitution - Missense	Central_nervous_system
COSM4848398	c.6637G>A	p.G2213R	Substitution - Missense	Cervix
COSM219271	c.2037G>A	p.M679I	Substitution - Missense	Breast
COSM253697	c.63C>A	p.S21S	Substitution - coding silent	Urinary_tract
COSM1713476	c.3295C>T	p.R1099W	Substitution - Missense	Skin
COSM3546361	c.4454C>T	p.S1485F	Substitution - Missense	Skin
COSM1026864	c.4251A>T	p.E1417D	Substitution - Missense	Endometrium
COSM443839	c.893delT	p.L298fs*61	Deletion - Frameshift	Breast
COSM13942	c.4974A>G	p.E1658E	Substitution - coding silent	Lung
COSM1026855	c.5124T>C	p.Y1708Y	Substitution - coding silent	Endometrium
COSM5392065	c.3957C>T	p.S1319S	Substitution - coding silent	Skin
COSM4495671	c.4590C>T	p.I1530I	Substitution - coding silent	Skin
COSM1200994	c.2428C>T	p.R810C	Substitution - Missense	Stomach
COSM3720001	c.6641A>T	p.E2214V	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3423651	c.2809C>T	p.R937*	Substitution - Nonsense	Large_intestine
COSM1615600	c.1962T>G	p.A654A	Substitution - coding silent	Liver
COSM1026880	c.2357T>C	p.V786A	Substitution - Missense	Endometrium
COSM2155611	c.5495G>A	p.C1832Y	Substitution - Missense	Central_nervous_system
COSM4136892	c.1234T>G	p.W412G	Substitution - Missense	Ovary
COSM5966783	c.1804A>G	p.R602G	Substitution - Missense	Adrenal_gland
COSM723653	c.2583G>T	p.A861A	Substitution - coding silent	Lung
COSM723658	c.4932A>G	p.T1644T	Substitution - coding silent	Lung
COSM3707762	c.3784G>A	p.V1262I	Substitution - Missense	Liver
COSM4973670	c.7345G>A	p.E2449K	Substitution - Missense	Oesophagus
COSM478164	c.6076G>T	p.D2026Y	Substitution - Missense	Kidney
COSM1026868	c.3838G>A	p.E1280K	Substitution - Missense	Skin
COSM4976464	c.2799G>A	p.Q933Q	Substitution - coding silent	Oesophagus
COSM1411832	c.5899C>A	p.L1967M	Substitution - Missense	Large_intestine
COSM577394	c.6930G>T	p.A2310A	Substitution - coding silent	Oesophagus
COSM3841023	c.1032C>T	p.I344I	Substitution - coding silent	Breast
COSM1026847	c.7116T>G	p.V2372V	Substitution - coding silent	Endometrium
COSM5453111	c.2606C>T	p.T869I	Substitution - Missense	Large_intestine
COSM187567	c.5926G>A	p.A1976T	Substitution - Missense	Stomach
COSM5590194	c.3462C>T	p.F1154F	Substitution - coding silent	Skin
COSM1026861	c.4622G>A	p.R1541H	Substitution - Missense	Endometrium
COSM3758572	c.6852G>A	p.T2284T	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM5909820	c.7106C>T	p.S2369F	Substitution - Missense	Skin
COSM1026842	c.7652C>T	p.P2551L	Substitution - Missense	Endometrium
COSM5938440	c.3058C>T	p.P1020S	Substitution - Missense	Skin
COSM4430706	c.5571G>A	p.L1857L	Substitution - coding silent	Oesophagus
COSM3546348	c.7987G>A	p.D2663N	Substitution - Missense	Skin
COSM1136792	c.2189A>G	p.N730S	Substitution - Missense	Kidney
COSM5574258	c.451G>A	p.A151T	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4098434	c.7711G>A	p.D2571N	Substitution - Missense	Stomach
COSM4649640	c.1233G>A	p.T411T	Substitution - coding silent	Large_intestine
COSM1533294	c.5925C>T	p.I1975I	Substitution - coding silent	Skin
COSM1757009	c.7533C>T	p.V2511V	Substitution - coding silent	Urinary_tract
COSM3291686	c.3836C>T	p.A1279V	Substitution - Missense	Large_intestine
COSM4672073	c.1713C>T	p.H571H	Substitution - coding silent	Large_intestine
COSM1495084	c.3188A>G	p.D1063G	Substitution - Missense	Kidney
COSM5037122	c.3524-9C>G	p.?	Unknown	Oesophagus
COSM1178877	c.3566C>T	p.T1189M	Substitution - Missense	Prostate
COSM4941722	c.4521G>A	p.R1507R	Substitution - coding silent	Liver
COSM5422314	c.7660C>G	p.L2554V	Substitution - Missense	Prostate
COSM4824290	c.7258C>T	p.L2420F	Substitution - Missense	Skin
COSM4476983	c.210C>T	p.T70T	Substitution - coding silent	Skin
COSM4408223	c.4408G>A	p.D1470N	Substitution - Missense	Pancreas
COSM1307403	c.5670A>T	p.V1890V	Substitution - coding silent	Urinary_tract
COSM4098469	c.1271A>C	p.K424T	Substitution - Missense	Stomach
COSM4966980	c.3705G>A	p.M1235I	Substitution - Missense	Small_intestine
COSM4642438	c.5877A>G	p.K1959K	Substitution - coding silent	Large_intestine
COSM5574491	c.6128A>G	p.D2043G	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3546368	c.3236C>T	p.P1079L	Substitution - Missense	Skin
COSM4098452	c.4657C>T	p.L1553F	Substitution - Missense	Stomach
COSM5650511	c.2240A>T	p.H747L	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1681679	c.7381C>T	p.P2461S	Substitution - Missense	Skin
COSM1661128	c.5418A>C	p.E1806D	Substitution - Missense	Kidney
COSM4443419	c.1619A>G	p.H540R	Substitution - Missense	Large_intestine
COSM6004501	c.4792T>C	p.C1598R	Substitution - Missense	Prostate
COSM3758573	c.6483C>G	p.H2161Q	Substitution - Missense	Large_intestine
COSM4098457	c.3164A>C	p.K1055T	Substitution - Missense	Stomach
COSM272494	c.2287C>T	p.R763*	Substitution - Nonsense	Large_intestine
COSM3291653	c.6104G>C	p.R2035T	Substitution - Missense	Urinary_tract
COSM382224	c.2986G>C	p.G996R	Substitution - Missense	Lung
COSM5569639	c.8140A>G	p.T2714A	Substitution - Missense	Prostate
COSM3911310	c.7472C>T	p.P2491L	Substitution - Missense	Skin
COSM4824290	c.7258C>T	p.L2420F	Substitution - Missense	Cervix
COSM219272	c.2029C>G	p.P677A	Substitution - Missense	Breast
COSM4959295	c.2002-1G>A	p.?	Unknown	Liver
COSM4098455	c.3177G>A	p.S1059S	Substitution - coding silent	Stomach
COSM1632296	c.7851A>G	p.V2617V	Substitution - coding silent	Liver
COSM1713477	c.2869C>T	p.R957W	Substitution - Missense	Skin
COSM1757010	c.4893C>T	p.C1631C	Substitution - coding silent	Urinary_tract
COSM3546349	c.7781C>T	p.S2594F	Substitution - Missense	Skin
COSM4526579	c.1403G>A	p.G468E	Substitution - Missense	Skin
COSM4389056	c.4105G>A	p.E1369K	Substitution - Missense	Pancreas
COSM1026846	c.7340_7364del25	p.R2447fs*15	Deletion - Frameshift	Endometrium
COSM1411843	c.2093T>G	p.I698S	Substitution - Missense	Large_intestine
COSM1734457	c.4318G>C	p.D1440H	Substitution - Missense	Pancreas
COSM5551922	c.756C>A	p.D252E	Substitution - Missense	Prostate
COSM3291667	c.4871A>C	p.Q1624P	Substitution - Missense	Large_intestine
COSM187596	c.1033G>A	p.A345T	Substitution - Missense	Large_intestine
COSM4428533	c.2020A>G	p.I674V	Substitution - Missense	Oesophagus
COSM4572562	c.7880T>C	p.F2627S	Substitution - Missense	Skin
COSM1411845	c.1442delA	p.N481fs*10	Deletion - Frameshift	Large_intestine
COSM5622878	c.2202C>T	p.L734L	Substitution - coding silent	Oesophagus
COSM77462	c.7462C>T	p.P2488S	Substitution - Missense	Ovary
COSM308646	c.3321_3322insT	p.G1108fs*39	Insertion - Frameshift	Lung
COSM5821207	c.3376A>T	p.N1126Y	Substitution - Missense	Liver
COSM5773796	c.8009A>C	p.E2670A	Substitution - Missense	Breast
COSM254612	c.1864A>T	p.K622*	Substitution - Nonsense	Urinary_tract
COSM1026852	c.5431G>A	p.A1811T	Substitution - Missense	Endometrium
COSM1713480	c.508A>G	p.R170G	Substitution - Missense	Skin
COSM3841022	c.1159A>G	p.K387E	Substitution - Missense	Breast
COSM1411824	c.7987delG	p.D2663fs*>53	Deletion - Frameshift	Large_intestine
COSM5057314	c.472delC	p.R158fs*53	Deletion - Frameshift	Stomach
COSM389413	c.4747G>A	p.D1583N	Substitution - Missense	Lung
COSM1307405	c.913G>A	p.E305K	Substitution - Missense	Urinary_tract
COSM1713479	c.1865A>C	p.K622T	Substitution - Missense	Skin
COSM1615602	c.1310A>G	p.H437R	Substitution - Missense	Liver
COSM1026878	c.2495G>A	p.R832Q	Substitution - Missense	Endometrium
COSM3291735	c.1477delA	p.T493fs*13	Deletion - Frameshift	Large_intestine
COSM4581819	c.3210G>A	p.E1070E	Substitution - coding silent	Bone
COSM443833	c.7587C>T	p.P2529P	Substitution - coding silent	Breast
COSM1197183	c.268A>G	p.T90A	Substitution - Missense	Soft_tissue
COSM4098467	c.1477A>G	p.T493A	Substitution - Missense	Stomach
COSM3546363	c.4148C>A	p.P1383Q	Substitution - Missense	Skin
COSM443838	c.1048C>T	p.R350*	Substitution - Nonsense	Endometrium
COSM1200986	c.3821T>C	p.V1274A	Substitution - Missense	Large_intestine
COSM4185923	c.5218A>C	p.S1740R	Substitution - Missense	Kidney
COSM5435345	c.1136G>A	p.R379H	Substitution - Missense	Oesophagus
COSM1026877	c.2671G>A	p.A891T	Substitution - Missense	Endometrium
COSM4606594	c.6385G>A	p.V2129I	Substitution - Missense	Adrenal_gland
COSM1615600	c.1962T>G	p.A654A	Substitution - coding silent	Liver
COSM5937854	c.1681-1G>A	p.?	Unknown	Skin
COSM3423648	c.7197C>T	p.S2399S	Substitution - coding silent	Large_intestine
COSM3291726	c.1773C>T	p.H591H	Substitution - coding silent	Large_intestine
COSM5464930	c.2716C>T	p.R906C	Substitution - Missense	Large_intestine
COSM4389056	c.4105G>A	p.E1369K	Substitution - Missense	Pancreas
COSM254611	c.7155G>C	p.Q2385H	Substitution - Missense	Urinary_tract
COSM1026872	c.3219C>T	p.S1073S	Substitution - coding silent	Upper_aerodigestive_tract
COSM3546356	c.6985C>T	p.P2329S	Substitution - Missense	Skin
COSM478163	c.7481G>A	p.G2494E	Substitution - Missense	Kidney
COSM324991	c.7942G>A	p.V2648I	Substitution - Missense	Lung
COSM1190260	c.6191T>A	p.I2064N	Substitution - Missense	Lung
COSM1307402	c.5728G>C	p.D1910H	Substitution - Missense	Urinary_tract
COSM243675	c.2600A>G	p.N867S	Substitution - Missense	Prostate
COSM1248219	c.8136C>T	p.N2712N	Substitution - coding silent	Oesophagus
COSM3911313	c.2210C>T	p.T737I	Substitution - Missense	Skin
COSM4136891	c.2253C>G	p.I751M	Substitution - Missense	Ovary
COSM3841016	c.8026G>A	p.E2676K	Substitution - Missense	Breast
COSM4672066	c.6379A>G	p.T2127A	Substitution - Missense	Large_intestine
COSM3379056	c.5638A>G	p.M1880V	Substitution - Missense	Pancreas
COSM5815123	c.108C>T	p.S36S	Substitution - coding silent	Liver
COSM1026856	c.5099C>A	p.P1700H	Substitution - Missense	Endometrium
COSM4794479	c.7634C>T	p.T2545I	Substitution - Missense	Liver
COSM1483640	c.4008-1G>C	p.?	Unknown	Breast
COSM443834	c.6409C>T	p.R2137*	Substitution - Nonsense	Breast
COSM368793	c.2513G>T	p.R838L	Substitution - Missense	Lung
COSM1411834	c.4806C>T	p.N1602N	Substitution - coding silent	Large_intestine
COSM1326736	c.2445A>G	p.L815L	Substitution - coding silent	Ovary
COSM4672065	c.7540A>G	p.T2514A	Substitution - Missense	Large_intestine
COSM4098436	c.7542C>T	p.T2514T	Substitution - coding silent	Stomach
COSM4581817	c.3627C>T	p.P1209P	Substitution - coding silent	Bone
COSM4852955	c.7217G>C	p.R2406T	Substitution - Missense	Cervix
COSM1681677	c.8112G>T	p.E2704D	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3371681	c.1533T>C	p.P511P	Substitution - coding silent	Thyroid
COSM4629410	c.4645C>T	p.R1549*	Substitution - Nonsense	Large_intestine
COSM4098464	c.2042G>T	p.R681L	Substitution - Missense	Stomach
COSM310083	c.2563T>C	p.F855L	Substitution - Missense	Lung
COSM5551924	c.755A>G	p.D252G	Substitution - Missense	Prostate
COSM3546374	c.1280A>G	p.E427G	Substitution - Missense	Skin
COSM459746	c.2856G>A	p.V952V	Substitution - coding silent	Cervix
COSM723659	c.6133C>T	p.P2045S	Substitution - Missense	Lung
COSM3291724	c.1948C>T	p.P650S	Substitution - Missense	Skin
COSM1743005	c.5014C>G	p.L1672V	Substitution - Missense	Biliary_tract
COSM4672067	c.6125A>G	p.Q2042R	Substitution - Missense	Large_intestine
COSM4672064	c.7894A>G	p.M2632V	Substitution - Missense	Large_intestine
COSM5365795	c.6983_6984delAC	p.H2328fs*2	Deletion - Frameshift	Large_intestine
COSM5933994	c.7318C>T	p.R2440C	Substitution - Missense	Skin
COSM4494736	c.4391C>T	p.S1464F	Substitution - Missense	Skin
COSM4451726	c.1375A>T	p.N459Y	Substitution - Missense	Skin
COSM5813913	c.2586A>T	p.G862G	Substitution - coding silent	Liver
COSM5606430	c.4316T>G	p.M1439R	Substitution - Missense	Skin
COSM359688	c.5086G>T	p.E1696*	Substitution - Nonsense	Lung
COSM5883564	c.5224G>C	p.D1742H	Substitution - Missense	Large_intestine
COSM1681679	c.7381C>T	p.P2461S	Substitution - Missense	Skin
COSM4098453	c.4003G>A	p.E1335K	Substitution - Missense	Stomach
COSM1026854	c.5213C>A	p.S1738*	Substitution - Nonsense	Endometrium
COSM3291724	c.1948C>T	p.P650S	Substitution - Missense	Skin
COSM4996023	c.1675G>A	p.A559T	Substitution - Missense	Upper_aerodigestive_tract
COSM3546369	c.3176C>T	p.S1059L	Substitution - Missense	Skin
COSM1200987	c.464G>A	p.R155Q	Substitution - Missense	Large_intestine
COSM3291714	c.2316C>T	p.D772D	Substitution - coding silent	Large_intestine
COSM4098465	c.1908G>A	p.E636E	Substitution - coding silent	Stomach
COSM4169332	c.8078C>T	p.P2693L	Substitution - Missense	Breast
COSM5057313	c.1482C>T	p.I494I	Substitution - coding silent	Stomach
COSM120035	c.4709A>G	p.Y1570C	Substitution - Missense	Ovary
COSM5741884	c.4133A>G	p.Q1378R	Substitution - Missense	Small_intestine
COSM5606430	c.4316T>G	p.M1439R	Substitution - Missense	Skin
COSM3291728	c.1704C>T	p.F568F	Substitution - coding silent	Large_intestine
COSM3546360	c.4474G>A	p.D1492N	Substitution - Missense	Skin
COSM5801450	c.2574_2575insA	p.T859fs*14	Insertion - Frameshift	Breast
COSM1615601	c.1837G>C	p.G613R	Substitution - Missense	Liver
COSM5662242	c.7426delA	p.M2476fs*4	Deletion - Frameshift	Soft_tissue
COSM4098439	c.6751G>A	p.A2251T	Substitution - Missense	Stomach
COSM13857	c.5860G>A	p.E1954K	Substitution - Missense	Lung
COSM187620	c.198G>T	p.E66D	Substitution - Missense	Large_intestine
COSM3546371	c.2569C>T	p.L857L	Substitution - coding silent	Skin
COSM108141	c.4419G>A	p.K1473K	Substitution - coding silent	Skin
COSM1681679	c.7381C>T	p.P2461S	Substitution - Missense	Skin
COSM1681681	c.4105G>T	p.E1369*	Substitution - Nonsense	Large_intestine
COSM1196685	c.2322G>T	p.Q774H	Substitution - Missense	Lung
COSM3546384	c.136G>A	p.E46K	Substitution - Missense	Skin
COSM5547844	c.3882_3885delTGAA	p.Y1294fs*1	Deletion - Frameshift	Prostate
COSM1026841	c.7706C>T	p.A2569V	Substitution - Missense	Endometrium
COSM4672069	c.3229G>A	p.E1077K	Substitution - Missense	Large_intestine
COSM3363249	c.3220G>C	p.D1074H	Substitution - Missense	Kidney
COSM1284109	c.3477C>T	p.I1159I	Substitution - coding silent	Autonomic_ganglia
COSM255445	c.1640A>C	p.Q547P	Substitution - Missense	Central_nervous_system
COSM1026885	c.117C>T	p.D39D	Substitution - coding silent	Endometrium
COSM3546376	c.935C>T	p.P312L	Substitution - Missense	Skin
COSM187606	c.664C>T	p.R222W	Substitution - Missense	Stomach
COSM1411824	c.7987delG	p.D2663fs*>53	Deletion - Frameshift	Large_intestine
COSM3546357	c.6427C>T	p.P2143S	Substitution - Missense	Skin
COSM5365821	c.2595delG	p.I866fs*31	Deletion - Frameshift	Large_intestine
COSM254611	c.7155G>C	p.Q2385H	Substitution - Missense	Urinary_tract
COSM254613	c.3404G>A	p.R1135H	Substitution - Missense	Urinary_tract
COSM5566948	c.2555G>T	p.R852L	Substitution - Missense	Prostate
COSM4672074	c.1528G>A	p.G510S	Substitution - Missense	Large_intestine
COSM1713475	c.7985G>A	p.G2662E	Substitution - Missense	Skin
COSM1161386	c.3404G>C	p.R1135P	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4672070	c.3031A>C	p.N1011H	Substitution - Missense	Large_intestine
COSM1196472	c.7213G>C	p.E2405Q	Substitution - Missense	Lung
COSM1681681	c.4105G>T	p.E1369*	Substitution - Nonsense	Large_intestine
COSM4753391	c.5147A>C	p.E1716A	Substitution - Missense	Stomach
COSM1681679	c.7381C>T	p.P2461S	Substitution - Missense	Skin
COSM4401003	c.773A>T	p.D258V	Substitution - Missense	Skin
COSM5820232	c.17A>C	p.Q6P	Substitution - Missense	Liver
COSM1681682	c.2709G>T	p.K903N	Substitution - Missense	Large_intestine
COSM5599298	c.7853C>T	p.S2618F	Substitution - Missense	Skin
COSM5819450	c.8084A>T	p.E2695V	Substitution - Missense	Liver
COSM3291676	c.4199G>A	p.R1400H	Substitution - Missense	Liver
COSM3727322	c.7199C>T	p.S2400F	Substitution - Missense	Skin
COSM3546382	c.367G>A	p.E123K	Substitution - Missense	Skin
COSM5036383	c.6886G>A	p.G2296R	Substitution - Missense	Oesophagus
COSM77463	c.3272G>A	p.R1091H	Substitution - Missense	Ovary
COSM1197183	c.268A>G	p.T90A	Substitution - Missense	Lung
COSM4134548	c.5457T>C	p.N1819N	Substitution - coding silent	Thyroid
COSM394227	c.288G>T	p.R96R	Substitution - coding silent	Lung
COSM4389056	c.4105G>A	p.E1369K	Substitution - Missense	Pancreas
COSM1026873	c.2862C>T	p.D954D	Substitution - coding silent	Endometrium
COSM4098440	c.6640G>A	p.E2214K	Substitution - Missense	Stomach
COSM4794479	c.7634C>T	p.T2545I	Substitution - Missense	Liver
COSM1632296	c.7851A>G	p.V2617V	Substitution - coding silent	Liver
COSM5936584	c.2860G>A	p.D954N	Substitution - Missense	Skin
COSM1200988	c.7300C>A	p.L2434I	Substitution - Missense	Large_intestine
COSM3389752	c.5215A>G	p.I1739V	Substitution - Missense	Pancreas
COSM4672072	c.2151G>T	p.K717N	Substitution - Missense	Large_intestine
COSM3389753	c.2158T>G	p.S720A	Substitution - Missense	Pancreas
COSM139189	c.4123C>T	p.R1375W	Substitution - Missense	Skin
COSM3546354	c.7350C>T	p.L2450L	Substitution - coding silent	Skin
COSM4800185	c.5495G>T	p.C1832F	Substitution - Missense	Liver
COSM443841	c.11A>C	p.K4T	Substitution - Missense	Breast
COSM254610	c.6481C>A	p.H2161N	Substitution - Missense	Urinary_tract
COSM5974049	c.1488C>T	p.S496S	Substitution - coding silent	Upper_aerodigestive_tract
COSM5392061	c.7768C>T	p.P2590S	Substitution - Missense	Skin
COSM1026879	c.2372T>G	p.L791R	Substitution - Missense	Endometrium
COSM5745442	c.5963C>T	p.P1988L	Substitution - Missense	Pancreas
COSM5599298	c.7853C>T	p.S2618F	Substitution - Missense	Skin
COSM3799545	c.7716G>C	p.K2572N	Substitution - Missense	Urinary_tract
COSM254614	c.64C>T	p.P22S	Substitution - Missense	Urinary_tract
COSM1713475	c.7985G>A	p.G2662E	Substitution - Missense	Liver
COSM4098463	c.2194C>T	p.P732S	Substitution - Missense	Stomach
COSM5350603	c.2614G>A	p.D872N	Substitution - Missense	Lung
COSM5702251	c.1681-1_1681GG>TT	p.?	Unknown	Soft_tissue
COSM5771759	c.3226G>C	p.D1076H	Substitution - Missense	Breast
COSM3972556	c.6471G>A	p.A2157A	Substitution - coding silent	Central_nervous_system
COSM254613	c.3404G>A	p.R1135H	Substitution - Missense	Skin
COSM3758572	c.6852G>A	p.T2284T	Substitution - coding silent	Large_intestine
COSM4098456	c.3170A>G	p.Y1057C	Substitution - Missense	Stomach
COSM4422536	c.6621C>A	p.I2207I	Substitution - coding silent	Kidney
COSM1026876	c.2691C>T	p.G897G	Substitution - coding silent	Endometrium
COSM4098437	c.7359T>C	p.A2453A	Substitution - coding silent	Stomach
COSM1681679	c.7381C>T	p.P2461S	Substitution - Missense	Skin
COSM1307401	c.5752G>C	p.E1918Q	Substitution - Missense	Urinary_tract
COSM3799544	c.7859G>T	p.G2620V	Substitution - Missense	Urinary_tract
COSM5916815	c.2735C>T	p.S912F	Substitution - Missense	Skin
COSM1026857	c.5069T>G	p.I1690S	Substitution - Missense	Endometrium
COSM3693690	c.2390C>T	p.A797V	Substitution - Missense	Large_intestine
COSM1483636	c.6819C>G	p.V2273V	Substitution - coding silent	Breast
COSM1200990	c.7886C>A	p.S2629Y	Substitution - Missense	Large_intestine
COSM3546372	c.2159C>T	p.S720F	Substitution - Missense	Skin
COSM3546375	c.1027C>T	p.R343C	Substitution - Missense	Skin
COSM5587487	c.2947C>T	p.L983L	Substitution - coding silent	Skin
COSM3911309	c.7838T>G	p.L2613R	Substitution - Missense	Skin
COSM369308	c.5794G>T	p.A1932S	Substitution - Missense	Lung
COSM1026848	c.6945C>T	p.V2315V	Substitution - coding silent	Endometrium
COSM4292006	c.1720A>G	p.I574V	Substitution - Missense	Large_intestine
COSM13942	c.4974A>G	p.E1658E	Substitution - coding silent	Lung
COSM3991702	c.3467G>C	p.W1156S	Substitution - Missense	Kidney
COSM1026872	c.3219C>T	p.S1073S	Substitution - coding silent	Large_intestine
COSM4098458	c.2992G>T	p.G998W	Substitution - Missense	Stomach
COSM5487086	c.4220G>A	p.R1407H	Substitution - Missense	Large_intestine
COSM723654	c.3381G>A	p.E1127E	Substitution - coding silent	Lung
COSM3405081	c.6376C>T	p.P2126S	Substitution - Missense	Central_nervous_system
COSM3770798	c.1880G>C	p.G627A	Substitution - Missense	Pancreas
COSM239311	c.2956C>T	p.R986*	Substitution - Nonsense	Prostate
COSM3546365	c.3557G>A	p.G1186E	Substitution - Missense	Skin
COSM4098459	c.2973C>T	p.T991T	Substitution - coding silent	Stomach
COSM5037043	c.7339C>T	p.R2447W	Substitution - Missense	Oesophagus
COSM723661	c.6861G>T	p.R2287R	Substitution - coding silent	Lung
COSM1026881	c.973T>G	p.F325V	Substitution - Missense	Endometrium
COSM1026871	c.3373C>A	p.L1125M	Substitution - Missense	Endometrium
COSM3291641	c.6860G>A	p.R2287Q	Substitution - Missense	Skin
COSM4469856	c.1623C>T	p.G541G	Substitution - coding silent	Skin
COSM239312	c.1546G>A	p.A516T	Substitution - Missense	Skin
COSM5458833	c.248A>C	p.E83A	Substitution - Missense	Large_intestine
COSM308646	c.3321_3322insT	p.G1108fs*39	Insertion - Frameshift	Soft_tissue
COSM1681680	c.5553A>C	p.K1851N	Substitution - Missense	Prostate
COSM5015670	c.1618C>A	p.H540N	Substitution - Missense	Kidney
COSM268886	c.706C>T	p.R236*	Substitution - Nonsense	Large_intestine
COSM4098462	c.2258-1G>T	p.?	Unknown	Stomach
COSM1727481	c.5807G>T	p.C1936F	Substitution - Missense	Liver
COSM1641347	c.681C>T	p.S227S	Substitution - coding silent	Stomach
COSM1743004	c.5659A>C	p.R1887R	Substitution - coding silent	Biliary_tract
COSM1411839	c.2500C>T	p.R834W	Substitution - Missense	Stomach
COSM3546359	c.4561C>T	p.P1521S	Substitution - Missense	Skin
COSM4672076	c.707G>A	p.R236Q	Substitution - Missense	Large_intestine
COSM3911312	c.6678C>T	p.S2226S	Substitution - coding silent	Skin
COSM5809184	c.7874C>A	p.S2625Y	Substitution - Missense	Liver
COSM577373	c.1549C>T	p.P517S	Substitution - Missense	Skin
COSM5899777	c.1427G>A	p.W476*	Substitution - Nonsense	Skin
COSM4098441	c.6489G>C	p.E2163D	Substitution - Missense	Stomach
COSM3841019	c.2437G>A	p.D813N	Substitution - Missense	Breast
COSM4753390	c.6272G>T	p.W2091L	Substitution - Missense	Stomach
COSM4098466	c.1497C>A	p.F499L	Substitution - Missense	Stomach
COSM1026865	c.4189C>G	p.R1397G	Substitution - Missense	Endometrium
COSM3291708	c.2595G>A	p.G865G	Substitution - coding silent	Upper_aerodigestive_tract
COSM74135	c.3865G>A	p.V1289M	Substitution - Missense	Ovary
COSM3841018	c.3334T>G	p.W1112G	Substitution - Missense	Breast
COSM4504440	c.6659C>T	p.S2220F	Substitution - Missense	Skin
COSM5662243	c.7421C>T	p.A2474V	Substitution - Missense	Soft_tissue
COSM419396	c.4008-1G>A	p.?	Unknown	Urinary_tract
COSM3713309	c.1028G>A	p.R343H	Substitution - Missense	Upper_aerodigestive_tract

> Text Mining based Variations

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PMID	Variation	Cancer	Evidence
24755471	Mutation	Colorectal Carcinoma	Furthermore, we documented mutations enriched in genes involved in chromatin remodeling (ARID1A, CHD6, and SRCAP) and histone methylation or acetylation (ASH1L, EP300, EP400, MLL2, MLL3, PRDM2, and TRRAP).
27270441	Mutation	Bladder Carcinoma	Non-silent sequence alterations were confirmed in 76 cancer-associated genes, including mutations that likely activate oncogenes TERT and PIK3CA, and alter chromatin-associated proteins (MLL3, ARID1A, CHD6 and KDM6A) and established BCa genes (TP53, RB1, CDKN2A and TSC1).

Summary
Symbol	CHD6
Name	chromodomain helicase DNA binding protein 6
Aliases	KIAA1335; FLJ22369; dJ620E11.1; RIGB; CHD-6; ATP-dependent helicase CHD6; helicase C-terminal domain- and SN ......
Location	20q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM) [ TOP ]
There is no PTM data

Summary
Symbol	CHD6
Name	chromodomain helicase DNA binding protein 6
Aliases	KIAA1335; FLJ22369; dJ620E11.1; RIGB; CHD-6; ATP-dependent helicase CHD6; helicase C-terminal domain- and SN ......
Location	20q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	6.055	5.72	-0.234	0.301	NS
BRCA	Breast invasive carcinoma	112	1100	6.609	6.498	-0.17	0.0335	NS
CESC	Cervical and endocervical cancers	3	306	5.957	5.463	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	4.789	5.4	0.508	4.44e-05	NS
ESCA	Esophageal carcinoma	11	185	6.513	6.352	-0.156	0.547	NS
GBM	Glioblastoma multiforme	5	166	6.493	5.735	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	5.389	5.306	0.057	0.691	NS
KIRC	Kidney renal clear cell carcinoma	72	534	6.171	5.859	-0.379	4.42e-09	NS
KIRP	Kidney renal papillary cell carcinoma	32	291	5.958	5.559	-0.39	0.0053	NS
LAML	Acute Myeloid Leukemia	0	173	NA	7.196	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	6.633	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	4.4	4.21	-0.222	0.0603	NS
LUAD	Lung adenocarcinoma	59	517	6.021	5.912	0.059	0.594	NS
LUSC	Lung squamous cell carcinoma	51	501	5.944	6.096	0.276	0.00798	NS
OV	Ovarian serous cystadenocarcinoma	0	307	NA	6.331	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	5.656	5.402	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	5.338	6.115	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	6.513	6.698	0.164	0.125	NS
READ	Rectum adenocarcinoma	10	167	4.981	5.582	0.539	0.0383	NS
SARC	Sarcoma	2	263	4.896	5.443	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	5.423	5.962	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	5.882	6.064	0.266	0.0419	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	6.316	NA	NA	NA
THCA	Thyroid carcinoma	59	509	6.647	6.21	-0.367	2.37e-06	NS
THYM	Thymoma	2	120	6.524	5.996	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	6.326	5.79	-0.501	3.6e-05	NS

> Cancer Cell Line Encyclopedia (CCLE)

[ TOP ]

Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	5.3
Autonomic ganglia	CHP212	5.1
Autonomic ganglia	IMR32	5.3
Autonomic ganglia	KELLY	5.6
Autonomic ganglia	KPNRTBM1	5.6
Autonomic ganglia	KPNSI9S	4.4
Autonomic ganglia	KPNYN	5.9
Autonomic ganglia	MHHNB11	4.8
Autonomic ganglia	NB1	5.3
Autonomic ganglia	NH6	5.6
Autonomic ganglia	SHSY5Y	5.3
Autonomic ganglia	SIMA	5.4
Autonomic ganglia	SKNAS	4.7
Autonomic ganglia	SKNBE2	5.4
Autonomic ganglia	SKNDZ	5.6
Autonomic ganglia	SKNFI	5
Autonomic ganglia	SKNSH	4.7
Biliary tract	HUCCT1	4.4
Biliary tract	HUH28	4.5
Biliary tract	SNU1079	4.7
Biliary tract	SNU1196	4.8
Biliary tract	SNU245	4.1
Biliary tract	SNU308	4.6
Biliary tract	SNU478	4.2
Bone	143B	5
Bone	A673	5
Bone	CADOES1	4.9
Bone	CAL78	4.7
Bone	G292CLONEA141B1	4.6
Bone	HOS	4.9
Bone	HS706T	4.6
Bone	HS737T	4.5
Bone	HS819T	4.4
Bone	HS821T	4.6
Bone	HS822T	4.8
Bone	HS863T	4.6
Bone	HS870T	4.6
Bone	HS888T	4.4
Bone	MG63	4.7
Bone	MHHES1	4.9
Bone	OUMS27	5.2
Bone	RDES	5.8
Bone	SJSA1	4.9
Bone	SKES1	5.2
Bone	SKNMC	5.1
Bone	SW1353	4.7
Bone	T173	4.6
Bone	TC71	4.7
Bone	U2OS	5.1
Breast	AU565	4.6
Breast	BT20	5.3
Breast	BT474	4.8
Breast	BT483	5.6
Breast	BT549	4.5
Breast	CAL120	5.1
Breast	CAL148	5.6
Breast	CAL51	5.2
Breast	CAL851	4.3
Breast	CAMA1	5.1
Breast	DU4475	4.3
Breast	EFM192A	4.5
Breast	EFM19	5.4
Breast	EVSAT	4.6
Breast	HCC1143	4.7
Breast	HCC1187	4.3
Breast	HCC1395	4.9
Breast	HCC1419	6.4
Breast	HCC1428	4.6
Breast	HCC1500	5
Breast	HCC1569	5.5
Breast	HCC1599	4.6
Breast	HCC1806	4.9
Breast	HCC1937	5
Breast	HCC1954	4.6
Breast	HCC202	4.4
Breast	HCC2157	4.9
Breast	HCC2218	4.6
Breast	HCC38	5.8
Breast	HCC70	4.4
Breast	HDQP1	4.9
Breast	HMC18	4.7
Breast	HS274T	4.6
Breast	HS281T	4.4
Breast	HS343T	4.3
Breast	HS578T	5.1
Breast	HS606T	4.8
Breast	HS739T	4.7
Breast	HS742T	4.5
Breast	JIMT1	4.7
Breast	KPL1	6.4
Breast	MCF7	6
Breast	MDAMB134VI	5.2
Breast	MDAMB157	5.2
Breast	MDAMB175VII	5.4
Breast	MDAMB231	4.5
Breast	MDAMB361	4.8
Breast	MDAMB415	5.9
Breast	MDAMB436	3.9
Breast	MDAMB453	4.9
Breast	MDAMB468	4.5
Breast	SKBR3	4.3
Breast	T47D	5.3
Breast	UACC812	4.8
Breast	UACC893	4.6
Breast	YMB1	4.9
Breast	ZR751	4.8
Breast	ZR7530	6
Central nervous system	1321N1	5.2
Central nervous system	42MGBA	5.3
Central nervous system	8MGBA	5
Central nervous system	A172	5.3
Central nervous system	AM38	4.3
Central nervous system	BECKER	4.8
Central nervous system	CAS1	5.2
Central nervous system	CCFSTTG1	4.3
Central nervous system	D283MED	5.4
Central nervous system	D341MED	5.4
Central nervous system	DAOY	4.8
Central nervous system	DBTRG05MG	4.7
Central nervous system	DKMG	5
Central nervous system	GAMG	4.8
Central nervous system	GB1	4.1
Central nervous system	GI1	5
Central nervous system	GMS10	6
Central nervous system	GOS3	4.8
Central nervous system	H4	4.7
Central nervous system	HS683	4.2
Central nervous system	KALS1	4.7
Central nervous system	KG1C	5.1
Central nervous system	KNS42	4.7
Central nervous system	KNS60	4.6
Central nervous system	KNS81	4.5
Central nervous system	KS1	4.8
Central nervous system	LN18	4.8
Central nervous system	LN229	5.4
Central nervous system	M059K	4.9
Central nervous system	MOGGCCM	4.7
Central nervous system	MOGGUVW	4.7
Central nervous system	NMCG1	4.4
Central nervous system	ONS76	5.4
Central nervous system	SF126	4.9
Central nervous system	SF295	4.2
Central nervous system	SNB19	4.6
Central nervous system	SNU1105	4.7
Central nervous system	SNU201	4.8
Central nervous system	SNU466	4.9
Central nervous system	SNU489	4.4
Central nervous system	SNU626	5.1
Central nervous system	SNU738	5.3
Central nervous system	SW1088	4.9
Central nervous system	SW1783	4.7
Central nervous system	T98G	5.3
Central nervous system	TM31	4.6
Central nervous system	U118MG	4.5
Central nervous system	U138MG	4.8
Central nervous system	U251MG	4.7
Central nervous system	U87MG	4.3
Central nervous system	YH13	4.4
Central nervous system	YKG1	5.3
Endometrium	AN3CA	4.2
Endometrium	COLO684	4.7
Endometrium	EFE184	4.8
Endometrium	EN	4.8
Endometrium	ESS1	5.4
Endometrium	HEC108	5.3
Endometrium	HEC151	4.4
Endometrium	HEC1A	4.5
Endometrium	HEC1B	4.8
Endometrium	HEC251	4.7
Endometrium	HEC265	4.4
Endometrium	HEC50B	4.7
Endometrium	HEC59	4.8
Endometrium	HEC6	4.5
Endometrium	ISHIKAWAHERAKLIO02ER	4.6
Endometrium	JHUEM1	4.5
Endometrium	JHUEM2	5
Endometrium	JHUEM3	4.5
Endometrium	KLE	4.4
Endometrium	MFE280	5.4
Endometrium	MFE296	4.4
Endometrium	MFE319	4.1
Endometrium	RL952	4.6
Endometrium	SNGM	4.9
Endometrium	SNU1077	4.9
Endometrium	SNU685	4.3
Endometrium	TEN	5
Haematopoietic and lymphoid	697	5.1
Haematopoietic and lymphoid	A3KAW	4.4
Haematopoietic and lymphoid	A4FUK	4.4
Haematopoietic and lymphoid	ALLSIL	5.7
Haematopoietic and lymphoid	AML193	4.6
Haematopoietic and lymphoid	AMO1	4.8
Haematopoietic and lymphoid	BCP1	4.8
Haematopoietic and lymphoid	BDCM	5
Haematopoietic and lymphoid	BL41	4.5
Haematopoietic and lymphoid	BL70	4.6
Haematopoietic and lymphoid	BV173	4.8
Haematopoietic and lymphoid	CA46	5.2
Haematopoietic and lymphoid	CI1	4.6
Haematopoietic and lymphoid	CMK115	4.5
Haematopoietic and lymphoid	CMK86	4.3
Haematopoietic and lymphoid	CMK	4.7
Haematopoietic and lymphoid	CMLT1	5.2
Haematopoietic and lymphoid	COLO775	4.7
Haematopoietic and lymphoid	DAUDI	4.9
Haematopoietic and lymphoid	DB	6
Haematopoietic and lymphoid	DEL	4.8
Haematopoietic and lymphoid	DND41	5.5
Haematopoietic and lymphoid	DOHH2	4.8
Haematopoietic and lymphoid	EB1	4.8
Haematopoietic and lymphoid	EB2	5.3
Haematopoietic and lymphoid	EHEB	4.6
Haematopoietic and lymphoid	EJM	4.6
Haematopoietic and lymphoid	EM2	5.1
Haematopoietic and lymphoid	EOL1	4.8
Haematopoietic and lymphoid	F36P	4.9
Haematopoietic and lymphoid	GA10	4.6
Haematopoietic and lymphoid	GDM1	5.3
Haematopoietic and lymphoid	GRANTA519	5.1
Haematopoietic and lymphoid	HDLM2	4.2
Haematopoietic and lymphoid	HDMYZ	4.6
Haematopoietic and lymphoid	HEL9217	4.5
Haematopoietic and lymphoid	HEL	4.5
Haematopoietic and lymphoid	HH	4.6
Haematopoietic and lymphoid	HL60	5.2
Haematopoietic and lymphoid	HPBALL	5.1
Haematopoietic and lymphoid	HS604T	4.2
Haematopoietic and lymphoid	HS611T	4.6
Haematopoietic and lymphoid	HS616T	4.7
Haematopoietic and lymphoid	HS751T	4.7
Haematopoietic and lymphoid	HT	4.8
Haematopoietic and lymphoid	HTK	4.6
Haematopoietic and lymphoid	HUNS1	4.5
Haematopoietic and lymphoid	HUT102	4.4
Haematopoietic and lymphoid	HUT78	4.9
Haematopoietic and lymphoid	JEKO1	5.3
Haematopoietic and lymphoid	JK1	4.4
Haematopoietic and lymphoid	JM1	5.4
Haematopoietic and lymphoid	JURKAT	5.1
Haematopoietic and lymphoid	JURLMK1	5.4
Haematopoietic and lymphoid	JVM2	4.7
Haematopoietic and lymphoid	JVM3	4.8
Haematopoietic and lymphoid	K562	4.4
Haematopoietic and lymphoid	KARPAS299	4.8
Haematopoietic and lymphoid	KARPAS422	5.6
Haematopoietic and lymphoid	KARPAS620	5.3
Haematopoietic and lymphoid	KASUMI1	5.2
Haematopoietic and lymphoid	KASUMI2	5
Haematopoietic and lymphoid	KASUMI6	5
Haematopoietic and lymphoid	KCL22	4.8
Haematopoietic and lymphoid	KE37	5.5
Haematopoietic and lymphoid	KE97	4.8
Haematopoietic and lymphoid	KG1	5.2
Haematopoietic and lymphoid	KHM1B	4.5
Haematopoietic and lymphoid	KIJK	4.6
Haematopoietic and lymphoid	KMH2	4.4
Haematopoietic and lymphoid	KMM1	5
Haematopoietic and lymphoid	KMS11	5.1
Haematopoietic and lymphoid	KMS12BM	4.9
Haematopoietic and lymphoid	KMS18	4.8
Haematopoietic and lymphoid	KMS20	4.8
Haematopoietic and lymphoid	KMS21BM	4.4
Haematopoietic and lymphoid	KMS26	4.6
Haematopoietic and lymphoid	KMS27	4.4
Haematopoietic and lymphoid	KMS28BM	4.5
Haematopoietic and lymphoid	KMS34	4.7
Haematopoietic and lymphoid	KO52	5.3
Haematopoietic and lymphoid	KOPN8	4.7
Haematopoietic and lymphoid	KU812	4.5
Haematopoietic and lymphoid	KYO1	4.4
Haematopoietic and lymphoid	L1236	5.5
Haematopoietic and lymphoid	L363	4.7
Haematopoietic and lymphoid	L428	4.3
Haematopoietic and lymphoid	L540	4.4
Haematopoietic and lymphoid	LAMA84	4.8
Haematopoietic and lymphoid	LOUCY	5.6
Haematopoietic and lymphoid	LP1	4.8
Haematopoietic and lymphoid	M07E	5.2
Haematopoietic and lymphoid	MC116	4.5
Haematopoietic and lymphoid	ME1	5.1
Haematopoietic and lymphoid	MEC1	4.9
Haematopoietic and lymphoid	MEC2	5
Haematopoietic and lymphoid	MEG01	4.8
Haematopoietic and lymphoid	MHHCALL2	5.2
Haematopoietic and lymphoid	MHHCALL3	4.8
Haematopoietic and lymphoid	MHHCALL4	5.8
Haematopoietic and lymphoid	MINO	4.9
Haematopoietic and lymphoid	MJ	4.4
Haematopoietic and lymphoid	MM1S	4.8
Haematopoietic and lymphoid	MOLM13	4.9
Haematopoietic and lymphoid	MOLM16	5.2
Haematopoietic and lymphoid	MOLM6	4.3
Haematopoietic and lymphoid	MOLP2	4.1
Haematopoietic and lymphoid	MOLP8	4.4
Haematopoietic and lymphoid	MOLT13	5.6
Haematopoietic and lymphoid	MOLT16	5.4
Haematopoietic and lymphoid	MOLT4	5.2
Haematopoietic and lymphoid	MONOMAC1	4.3
Haematopoietic and lymphoid	MONOMAC6	4.7
Haematopoietic and lymphoid	MOTN1	4.6
Haematopoietic and lymphoid	MUTZ5	5.4
Haematopoietic and lymphoid	MV411	4.8
Haematopoietic and lymphoid	NALM19	5
Haematopoietic and lymphoid	NALM1	5.3
Haematopoietic and lymphoid	NALM6	5.4
Haematopoietic and lymphoid	NAMALWA	4.8
Haematopoietic and lymphoid	NB4	5.1
Haematopoietic and lymphoid	NCIH929	4.9
Haematopoietic and lymphoid	NCO2	4.8
Haematopoietic and lymphoid	NOMO1	4.9
Haematopoietic and lymphoid	NUDHL1	4.6
Haematopoietic and lymphoid	NUDUL1	5.2
Haematopoietic and lymphoid	OCIAML2	4.5
Haematopoietic and lymphoid	OCIAML3	4.7
Haematopoietic and lymphoid	OCIAML5	4.6
Haematopoietic and lymphoid	OCILY10	4.7
Haematopoietic and lymphoid	OCILY19	5.2
Haematopoietic and lymphoid	OCILY3	5.3
Haematopoietic and lymphoid	OCIM1	4.9
Haematopoietic and lymphoid	OPM2	5
Haematopoietic and lymphoid	P12ICHIKAWA	5.6
Haematopoietic and lymphoid	P31FUJ	5
Haematopoietic and lymphoid	P3HR1	4.5
Haematopoietic and lymphoid	PCM6	4.3
Haematopoietic and lymphoid	PEER	5.2
Haematopoietic and lymphoid	PF382	6
Haematopoietic and lymphoid	PFEIFFER	4.5
Haematopoietic and lymphoid	PL21	4.9
Haematopoietic and lymphoid	RAJI	4.6
Haematopoietic and lymphoid	RCHACV	5
Haematopoietic and lymphoid	REC1	4.8
Haematopoietic and lymphoid	REH	5.3
Haematopoietic and lymphoid	RI1	4.7
Haematopoietic and lymphoid	RL	4.9
Haematopoietic and lymphoid	RPMI8226	4.5
Haematopoietic and lymphoid	RPMI8402	6.1
Haematopoietic and lymphoid	RS411	4.8
Haematopoietic and lymphoid	SEM	5.6
Haematopoietic and lymphoid	SET2	5
Haematopoietic and lymphoid	SIGM5	5.1
Haematopoietic and lymphoid	SKM1	4.9
Haematopoietic and lymphoid	SKMM2	5.1
Haematopoietic and lymphoid	SR786	4.9
Haematopoietic and lymphoid	ST486	4.8
Haematopoietic and lymphoid	SUDHL10	5.4
Haematopoietic and lymphoid	SUDHL1	5.3
Haematopoietic and lymphoid	SUDHL4	4.9
Haematopoietic and lymphoid	SUDHL5	4.7
Haematopoietic and lymphoid	SUDHL6	4.8
Haematopoietic and lymphoid	SUDHL8	5.6
Haematopoietic and lymphoid	SUPB15	5.3
Haematopoietic and lymphoid	SUPHD1	4.5
Haematopoietic and lymphoid	SUPM2	4.8
Haematopoietic and lymphoid	SUPT11	5
Haematopoietic and lymphoid	SUPT1	5.2
Haematopoietic and lymphoid	TALL1	6.5
Haematopoietic and lymphoid	TF1	4.6
Haematopoietic and lymphoid	THP1	4.4
Haematopoietic and lymphoid	TO175T	4.7
Haematopoietic and lymphoid	TOLEDO	5.7
Haematopoietic and lymphoid	U266B1	4.5
Haematopoietic and lymphoid	U937	5
Haematopoietic and lymphoid	UT7	5.1
Haematopoietic and lymphoid	WSUDLCL2	5.6
Kidney	769P	4.1
Kidney	786O	4.2
Kidney	A498	4.4
Kidney	A704	4.4
Kidney	ACHN	4.4
Kidney	BFTC909	4.6
Kidney	CAKI1	4.8
Kidney	CAKI2	4.6
Kidney	CAL54	4.7
Kidney	KMRC1	4.3
Kidney	KMRC20	4.1
Kidney	KMRC2	4.3
Kidney	KMRC3	5
Kidney	OSRC2	4.7
Kidney	RCC10RGB	4.5
Kidney	SNU1272	4.6
Kidney	SNU349	4.1
Kidney	TUHR10TKB	4.4
Kidney	TUHR14TKB	4.2
Kidney	TUHR4TKB	4.9
Kidney	VMRCRCW	4.3
Kidney	VMRCRCZ	4.5
Large intestine	C2BBE1	4.8
Large intestine	CCK81	4.6
Large intestine	CL11	4.5
Large intestine	CL14	4.8
Large intestine	CL34	4.2
Large intestine	CL40	4.1
Large intestine	COLO205	4.6
Large intestine	COLO320	5.1
Large intestine	COLO678	5.7
Large intestine	CW2	3.9
Large intestine	DLD1	4.5
Large intestine	GP2D	4.4
Large intestine	HCC56	4.7
Large intestine	HCT116	4.1
Large intestine	HCT15	4.5
Large intestine	HS675T	4.4
Large intestine	HS698T	4.5
Large intestine	HT115	4.2
Large intestine	HT29	4.9
Large intestine	HT55	4.3
Large intestine	KM12	5
Large intestine	LOVO	4.4
Large intestine	LS1034	5
Large intestine	LS123	5.1
Large intestine	LS180	4.6
Large intestine	LS411N	4.7
Large intestine	LS513	4.1
Large intestine	MDST8	4.8
Large intestine	NCIH508	5.1
Large intestine	NCIH716	4.9
Large intestine	NCIH747	5.3
Large intestine	OUMS23	5.4
Large intestine	RCM1	5
Large intestine	RKO	4.3
Large intestine	SKCO1	4.6
Large intestine	SNU1040	4.6
Large intestine	SNU1197	4.5
Large intestine	SNU175	4.5
Large intestine	SNU283	4.5
Large intestine	SNU407	4.1
Large intestine	SNU503	5.1
Large intestine	SNU61	3.9
Large intestine	SNU81	4.3
Large intestine	SNUC1	4.5
Large intestine	SNUC2A	4.9
Large intestine	SNUC4	4.1
Large intestine	SNUC5	4.7
Large intestine	SW1116	4.7
Large intestine	SW1417	6
Large intestine	SW1463	4.7
Large intestine	SW403	4.9
Large intestine	SW480	4.9
Large intestine	SW48	5
Large intestine	SW620	5
Large intestine	SW837	5.1
Large intestine	SW948	5.2
Large intestine	T84	4.5
Liver	ALEXANDERCELLS	4.4
Liver	C3A	5.1
Liver	HEP3B217	4.7
Liver	HEPG2	5.3
Liver	HLE	4.8
Liver	HLF	4.7
Liver	HUH1	4.7
Liver	HUH6	4.8
Liver	HUH7	4.9
Liver	JHH1	5.1
Liver	JHH2	4.6
Liver	JHH4	5.2
Liver	JHH5	4.9
Liver	JHH6	4.9
Liver	JHH7	5
Liver	LI7	4.4
Liver	PLCPRF5	4.3
Liver	SKHEP1	4.7
Liver	SNU182	4.7
Liver	SNU387	4.7
Liver	SNU398	4.4
Liver	SNU423	4.6
Liver	SNU449	4.7
Liver	SNU475	5.3
Liver	SNU761	4.8
Liver	SNU878	4.6
Liver	SNU886	4.3
Lung	A549	4.6
Lung	ABC1	5.1
Lung	BEN	5.7
Lung	CAL12T	4.5
Lung	CALU1	4.7
Lung	CALU3	5.1
Lung	CALU6	5
Lung	CHAGOK1	5.2
Lung	COLO668	5.4
Lung	COLO699	5
Lung	CORL105	4.6
Lung	CORL23	4.9
Lung	CORL24	5.4
Lung	CORL279	6
Lung	CORL311	5.9
Lung	CORL47	5.2
Lung	CORL51	5.6
Lung	CORL88	5.9
Lung	CORL95	5.1
Lung	CPCN	5.1
Lung	DMS114	4.4
Lung	DMS153	6
Lung	DMS273	4.4
Lung	DMS454	5.4
Lung	DMS53	5.6
Lung	DMS79	5.4
Lung	DV90	4
Lung	EBC1	4.7
Lung	EPLC272H	4.5
Lung	HARA	4.4
Lung	HCC1171	4.9
Lung	HCC1195	4.8
Lung	HCC15	4.2
Lung	HCC2279	4.6
Lung	HCC2935	4.7
Lung	HCC33	5.7
Lung	HCC366	4.7
Lung	HCC4006	4.1
Lung	HCC44	4.2
Lung	HCC78	4.5
Lung	HCC827	4.6
Lung	HCC95	5.3
Lung	HLC1	4.7
Lung	HLFA	4.6
Lung	HS229T	4.4
Lung	HS618T	4.5
Lung	IALM	5
Lung	KNS62	4.4
Lung	LC1F	5.5
Lung	LC1SQSF	5.4
Lung	LCLC103H	4.3
Lung	LCLC97TM1	4.5
Lung	LK2	4.7
Lung	LOUNH91	4.6
Lung	LU65	4.3
Lung	LU99	4.9
Lung	LUDLU1	5.5
Lung	LXF289	4.4
Lung	MORCPR	4.7
Lung	NCIH1048	5.7
Lung	NCIH1092	5.8
Lung	NCIH1105	6.7
Lung	NCIH1155	5
Lung	NCIH1184	5.2
Lung	NCIH1299	4.4
Lung	NCIH1339	4.7
Lung	NCIH1341	5.2
Lung	NCIH1355	4.3
Lung	NCIH1373	4.4
Lung	NCIH1385	5.4
Lung	NCIH1395	4.3
Lung	NCIH1435	4.3
Lung	NCIH1436	5.4
Lung	NCIH1437	4.5
Lung	NCIH146	6
Lung	NCIH1563	5.1
Lung	NCIH1568	4.5
Lung	NCIH1573	5
Lung	NCIH1581	4.8
Lung	NCIH1618	6.4
Lung	NCIH1623	4.4
Lung	NCIH1648	4.9
Lung	NCIH1650	4.9
Lung	NCIH1651	4.6
Lung	NCIH1666	5.3
Lung	NCIH1693	4.2
Lung	NCIH1694	5.6
Lung	NCIH1703	4.6
Lung	NCIH1734	4.5
Lung	NCIH1755	4.8
Lung	NCIH1781	5.3
Lung	NCIH1792	4.5
Lung	NCIH1793	4.7
Lung	NCIH1836	6.3
Lung	NCIH1838	4.7
Lung	NCIH1869	4
Lung	NCIH1876	5.3
Lung	NCIH1915	4.5
Lung	NCIH1930	5
Lung	NCIH1944	4.1
Lung	NCIH1963	5.5
Lung	NCIH196	5.2
Lung	NCIH1975	4.9
Lung	NCIH2009	5.3
Lung	NCIH2023	4.6
Lung	NCIH2029	6.6
Lung	NCIH2030	4.5
Lung	NCIH2066	6.1
Lung	NCIH2081	5.2
Lung	NCIH2085	4.8
Lung	NCIH2087	4.5
Lung	NCIH209	5.9
Lung	NCIH2106	4.8
Lung	NCIH2110	4.6
Lung	NCIH211	5.4
Lung	NCIH2122	4.7
Lung	NCIH2126	4.8
Lung	NCIH2141	5.3
Lung	NCIH2170	4.8
Lung	NCIH2171	5.7
Lung	NCIH2172	5.2
Lung	NCIH2196	5.5
Lung	NCIH2227	5.5
Lung	NCIH2228	4.2
Lung	NCIH226	4.4
Lung	NCIH2286	4.5
Lung	NCIH2291	4.5
Lung	NCIH2342	5.4
Lung	NCIH2347	4
Lung	NCIH23	4.9
Lung	NCIH2405	4.8
Lung	NCIH2444	4.5
Lung	NCIH292	4.4
Lung	NCIH322	4.5
Lung	NCIH3255	4.5
Lung	NCIH358	5.1
Lung	NCIH441	4.9
Lung	NCIH446	4.9
Lung	NCIH460	4.6
Lung	NCIH510	6.4
Lung	NCIH520	4.8
Lung	NCIH522	4.7
Lung	NCIH524	5.4
Lung	NCIH526	6
Lung	NCIH596	5.1
Lung	NCIH647	4.4
Lung	NCIH650	5
Lung	NCIH661	4.7
Lung	NCIH69	4.7
Lung	NCIH727	5.3
Lung	NCIH810	5.9
Lung	NCIH82	5
Lung	NCIH838	4.9
Lung	NCIH841	4.3
Lung	NCIH854	5.7
Lung	NCIH889	5.7
Lung	PC14	4.6
Lung	RERFLCAD1	5.4
Lung	RERFLCAD2	4.2
Lung	RERFLCAI	4.1
Lung	RERFLCKJ	4.7
Lung	RERFLCMS	4.3
Lung	RERFLCSQ1	4.9
Lung	SBC5	4.3
Lung	SCLC21H	5.6
Lung	SHP77	4.7
Lung	SKLU1	4.1
Lung	SKMES1	5
Lung	SQ1	4.3
Lung	SW1271	4.7
Lung	SW1573	4.6
Lung	SW900	4.4
Lung	VMRCLCD	4
Lung	VMRCLCP	4.7
Oesophagus	COLO680N	4.7
Oesophagus	ECGI10	4.1
Oesophagus	KYSE140	4.7
Oesophagus	KYSE150	4.5
Oesophagus	KYSE180	4.6
Oesophagus	KYSE270	4.5
Oesophagus	KYSE30	4.6
Oesophagus	KYSE410	5.1
Oesophagus	KYSE450	5.1
Oesophagus	KYSE510	5
Oesophagus	KYSE520	5.4
Oesophagus	KYSE70	5.3
Oesophagus	OE19	4.4
Oesophagus	OE33	4.9
Oesophagus	TE10	4.3
Oesophagus	TE11	4.8
Oesophagus	TE14	5.2
Oesophagus	TE15	5
Oesophagus	TE1	4.7
Oesophagus	TE4	4.2
Oesophagus	TE5	5
Oesophagus	TE6	5.6
Oesophagus	TE8	5.5
Oesophagus	TE9	4.5
Oesophagus	TT	5.1
Ovary	59M	4.4
Ovary	A2780	4.9
Ovary	CAOV3	4.5
Ovary	CAOV4	5.9
Ovary	COLO704	4.8
Ovary	COV318	5.1
Ovary	COV362	4.4
Ovary	COV434	4.7
Ovary	COV504	4
Ovary	COV644	4
Ovary	EFO21	5.1
Ovary	EFO27	5.2
Ovary	ES2	4.3
Ovary	FUOV1	5.3
Ovary	HEYA8	4.3
Ovary	HS571T	4.7
Ovary	IGROV1	4.9
Ovary	JHOC5	4.4
Ovary	JHOM1	5.5
Ovary	JHOM2B	5.1
Ovary	JHOS2	4.3
Ovary	JHOS4	5
Ovary	KURAMOCHI	4.9
Ovary	MCAS	4.1
Ovary	NIHOVCAR3	4.9
Ovary	OAW28	4.8
Ovary	OAW42	4.1
Ovary	OC314	4.9
Ovary	OC316	4.8
Ovary	ONCODG1	5.2
Ovary	OV56	4.5
Ovary	OV7	4.2
Ovary	OV90	4.8
Ovary	OVCAR4	4.6
Ovary	OVCAR8	4.8
Ovary	OVISE	4.8
Ovary	OVK18	4.5
Ovary	OVKATE	4.9
Ovary	OVMANA	4.6
Ovary	OVSAHO	5.9
Ovary	OVTOKO	4.5
Ovary	RMGI	4.5
Ovary	RMUGS	4.6
Ovary	SKOV3	4.6
Ovary	SNU119	4.8
Ovary	SNU840	4.6
Ovary	SNU8	4.8
Ovary	TOV112D	4.6
Ovary	TOV21G	4.8
Ovary	TYKNU	4.5
Pancreas	ASPC1	4.6
Pancreas	BXPC3	4.2
Pancreas	CAPAN1	4.7
Pancreas	CAPAN2	4.5
Pancreas	CFPAC1	4.6
Pancreas	DANG	4.6
Pancreas	HPAC	5.1
Pancreas	HPAFII	4.5
Pancreas	HS766T	5.2
Pancreas	HUPT3	4.5
Pancreas	HUPT4	4.5
Pancreas	KCIMOH1	5.3
Pancreas	KLM1	4.9
Pancreas	KP2	5.1
Pancreas	KP3	4.5
Pancreas	KP4	4.8
Pancreas	L33	5.4
Pancreas	MIAPACA2	5
Pancreas	PANC0203	4.5
Pancreas	PANC0213	4.9
Pancreas	PANC0327	4.7
Pancreas	PANC0403	4.5
Pancreas	PANC0504	4.7
Pancreas	PANC0813	4.5
Pancreas	PANC1005	4.5
Pancreas	PANC1	4.4
Pancreas	PATU8902	4.6
Pancreas	PATU8988S	4.9
Pancreas	PATU8988T	4.4
Pancreas	PK1	4.6
Pancreas	PK45H	4.8
Pancreas	PK59	5.4
Pancreas	PL45	4.9
Pancreas	PSN1	4.8
Pancreas	QGP1	5.7
Pancreas	SNU213	4.7
Pancreas	SNU324	4.4
Pancreas	SNU410	4.7
Pancreas	SU8686	4.7
Pancreas	SUIT2	4.9
Pancreas	SW1990	4.9
Pancreas	T3M4	4.5
Pancreas	TCCPAN2	4.6
Pancreas	YAPC	4.8
Pleura	ACCMESO1	4.3
Pleura	DM3	4.4
Pleura	ISTMES1	5.2
Pleura	ISTMES2	4.7
Pleura	JL1	4.8
Pleura	MPP89	5
Pleura	MSTO211H	4.7
Pleura	NCIH2052	5.1
Pleura	NCIH2452	4.6
Pleura	NCIH28	4.8
Prostate	22RV1	5
Prostate	DU145	4.4
Prostate	LNCAPCLONEFGC	5.7
Prostate	MDAPCA2B	5.5
Prostate	NCIH660	6.2
Prostate	PC3	4.4
Prostate	VCAP	6.2
Salivary gland	A253	4.7
Salivary gland	YD15	4.5
Skin	A101D	4.6
Skin	A2058	4.2
Skin	A375	4.8
Skin	C32	5.4
Skin	CHL1	4.5
Skin	CJM	4.8
Skin	COLO679	5.1
Skin	COLO741	5
Skin	COLO783	5
Skin	COLO792	4.9
Skin	COLO800	5.3
Skin	COLO818	4.9
Skin	COLO829	5.1
Skin	COLO849	4.8
Skin	G361	5
Skin	GRM	4.5
Skin	HMCB	4.7
Skin	HS294T	4.6
Skin	HS600T	4.6
Skin	HS688AT	4.7
Skin	HS695T	4.7
Skin	HS839T	4.2
Skin	HS852T	4.7
Skin	HS895T	4.1
Skin	HS934T	4.3
Skin	HS936T	4.6
Skin	HS939T	4.5
Skin	HS940T	4.6
Skin	HS944T	4.5
Skin	HT144	5
Skin	IGR1	4.8
Skin	IGR37	4.3
Skin	IGR39	4.5
Skin	IPC298	4.8
Skin	K029AX	4.6
Skin	LOXIMVI	4.7
Skin	MALME3M	5
Skin	MDAMB435S	4.5
Skin	MELHO	5
Skin	MELJUSO	4.6
Skin	MEWO	4.8
Skin	RPMI7951	4.6
Skin	RVH421	5.3
Skin	SH4	5
Skin	SKMEL1	5.1
Skin	SKMEL24	4.7
Skin	SKMEL28	4.8
Skin	SKMEL2	4.8
Skin	SKMEL30	5.4
Skin	SKMEL31	4.7
Skin	SKMEL3	5.5
Skin	SKMEL5	4.4
Skin	UACC257	4.4
Skin	UACC62	4.8
Skin	WM115	4.7
Skin	WM1799	4.8
Skin	WM2664	4.5
Skin	WM793	4.3
Skin	WM88	4.8
Skin	WM983B	5.3
Small intestine	HUTU80	4.7
Soft tissue	A204	4.6
Soft tissue	G401	4.7
Soft tissue	G402	4.5
Soft tissue	GCT	4.6
Soft tissue	HS729	5.4
Soft tissue	HT1080	4.4
Soft tissue	KYM1	4.9
Soft tissue	MESSA	4.8
Soft tissue	RD	4.9
Soft tissue	RH30	4.4
Soft tissue	RH41	5.5
Soft tissue	RKN	5.7
Soft tissue	S117	4.6
Soft tissue	SJRH30	5.8
Soft tissue	SKLMS1	4.8
Soft tissue	SKUT1	5
Soft tissue	TE125T	4.3
Soft tissue	TE159T	4.6
Soft tissue	TE441T	4.9
Soft tissue	TE617T	4.4
Stomach	2313287	4.3
Stomach	AGS	5.8
Stomach	AZ521	4.4
Stomach	ECC10	5.8
Stomach	ECC12	6.4
Stomach	FU97	4.7
Stomach	GCIY	4.6
Stomach	GSS	5
Stomach	GSU	4.4
Stomach	HGC27	4.6
Stomach	HS746T	5.1
Stomach	HUG1N	4.4
Stomach	IM95	4.1
Stomach	KATOIII	4.6
Stomach	KE39	5.2
Stomach	LMSU	4
Stomach	MKN1	4.8
Stomach	MKN45	5.3
Stomach	MKN74	4.8
Stomach	MKN7	5.1
Stomach	NCCSTCK140	5
Stomach	NCIN87	4.7
Stomach	NUGC2	5.2
Stomach	NUGC3	4.8
Stomach	NUGC4	4.4
Stomach	OCUM1	4.5
Stomach	RERFGC1B	7
Stomach	SH10TC	4.3
Stomach	SNU16	4.4
Stomach	SNU1	5.2
Stomach	SNU216	5.3
Stomach	SNU520	3.7
Stomach	SNU5	4.3
Stomach	SNU601	4.2
Stomach	SNU620	4.7
Stomach	SNU668	4.5
Stomach	SNU719	4.8
Stomach	TGBC11TKB	5.1
Thyroid	8305C	4.9
Thyroid	8505C	5
Thyroid	BCPAP	5
Thyroid	BHT101	4.6
Thyroid	CAL62	5.7
Thyroid	CGTHW1	4.8
Thyroid	FTC133	4.2
Thyroid	FTC238	5.2
Thyroid	ML1	4.9
Thyroid	SW579	4.2
Thyroid	TT2609C02	4.3
Thyroid	TT	5.2
Upper aerodigestive tract	BHY	5
Upper aerodigestive tract	BICR16	4.3
Upper aerodigestive tract	BICR18	4.7
Upper aerodigestive tract	BICR22	4.5
Upper aerodigestive tract	BICR31	4.9
Upper aerodigestive tract	BICR56	4.8
Upper aerodigestive tract	BICR6	4.6
Upper aerodigestive tract	CAL27	5
Upper aerodigestive tract	CAL33	5
Upper aerodigestive tract	DETROIT562	4.4
Upper aerodigestive tract	FADU	4.9
Upper aerodigestive tract	HS840T	4.4
Upper aerodigestive tract	HSC2	4.6
Upper aerodigestive tract	HSC3	4.5
Upper aerodigestive tract	HSC4	6
Upper aerodigestive tract	PECAPJ15	4.8
Upper aerodigestive tract	PECAPJ34CLONEC12	4.4
Upper aerodigestive tract	PECAPJ41CLONED2	4.3
Upper aerodigestive tract	PECAPJ49	4.8
Upper aerodigestive tract	SCC15	4.6
Upper aerodigestive tract	SCC25	4.1
Upper aerodigestive tract	SCC4	4.7
Upper aerodigestive tract	SCC9	4.9
Upper aerodigestive tract	SNU1076	5.4
Upper aerodigestive tract	SNU1214	4.6
Upper aerodigestive tract	SNU46	4.5
Upper aerodigestive tract	SNU899	4.6
Upper aerodigestive tract	YD10B	5
Upper aerodigestive tract	YD38	4.4
Upper aerodigestive tract	YD8	5
Urinary tract	5637	4.7
Urinary tract	639V	4.7
Urinary tract	647V	4.8
Urinary tract	BC3C	5.1
Urinary tract	BFTC905	4.3
Urinary tract	CAL29	4.8
Urinary tract	HS172T	4.1
Urinary tract	HT1197	4.5
Urinary tract	HT1376	4.9
Urinary tract	J82	4.8
Urinary tract	JMSU1	4.9
Urinary tract	KMBC2	4.9
Urinary tract	KU1919	5
Urinary tract	RT11284	4.8
Urinary tract	RT112	5
Urinary tract	RT4	5.1
Urinary tract	SCABER	4.6
Urinary tract	SW1710	4.7
Urinary tract	SW780	5.6
Urinary tract	T24	5.3
Urinary tract	TCCSUP	4.4
Urinary tract	UMUC1	4.5
Urinary tract	UMUC3	4.6
Urinary tract	VMCUB1	4.8

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	6.6
Adrenal gland	10.2
Appendix	9.5
Bone marrow	8.6
Breast	15.3
Cerebral cortex	15.4
Cervix, uterine	14.4
Colon	5.3
Duodenum	4.1
Endometrium	20.9
Epididymis	15.4
Esophagus	6.3
Fallopian tube	16.4
Gallbladder	11.7
Heart muscle	5.4
Kidney	7.9
Liver	3.5
Lung	11.3
Lymph node	9.9
Ovary	19.8
Pancreas	1.7
Parathyroid gland	31
Placenta	11.9
Prostate	19.2
Rectum	6.9
Salivary gland	3.4
Seminal vesicle	13
Skeletal muscle	1.8
Skin	10
Small intestine	5.2
Smooth muscle	13.3
Spleen	11.4
Stomach	6.9
Testis	13.4
Thyroid gland	22.9
Tonsil	8
Urinary bladder	8.2

> Text Mining based Expression [ TOP ]
There is no record.

Summary
Symbol	CHD6
Name	chromodomain helicase DNA binding protein 6
Aliases	KIAA1335; FLJ22369; dJ620E11.1; RIGB; CHD-6; ATP-dependent helicase CHD6; helicase C-terminal domain- and SN ......
Location	20q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.372	1.13e-14	2.7	37.4	59.9	Gain
BRCA	Breast invasive carcinoma	1075	0.405	1e-43	6.7	51.2	42.1	Gain
CESC	Cervical and endocervical cancers	292	0.471	1.44e-17	4.5	53.8	41.8	Gain
COAD	Colon adenocarcinoma	449	0.479	3.8e-27	0.7	27.6	71.7	Gain
ESCA	Esophageal carcinoma	183	0.324	7.71e-06	2.7	31.1	66.1	Gain
GBM	Glioblastoma multiforme	147	0.234	0.0044	2	60.5	37.4	Gain
HNSC	Head and Neck squamous cell carcinoma	514	0.266	9.14e-10	6.6	55.6	37.7	Gain
KIRC	Kidney renal clear cell carcinoma	525	0.056	0.2	0	77.5	22.5	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	0.36	2.97e-10	0.7	64.2	35.1	Gain
LAML	Acute Myeloid Leukemia	166	0.218	0.0048	1.8	98.2	0	Neutral
LGG	Brain Lower Grade Glioma	513	0.077	0.0821	0.6	90.6	8.8	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.204	9.15e-05	3	64.8	32.1	Neutral
LUAD	Lung adenocarcinoma	512	0.456	1.17e-27	16	44.9	39.1	Gain
LUSC	Lung squamous cell carcinoma	498	0.377	3.07e-18	9	38.6	52.4	Gain
OV	Ovarian serous cystadenocarcinoma	300	0.519	4.75e-22	8.3	36.3	55.3	Gain
PAAD	Pancreatic adenocarcinoma	177	0.397	4.63e-08	2.3	71.8	26	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	0.269	0.00055	1.9	92	6.2	Neutral
PRAD	Prostate adenocarcinoma	491	0.171	0.000138	2.6	90.6	6.7	Neutral
READ	Rectum adenocarcinoma	164	0.354	3.33e-06	0	11	89	Gain
SARC	Sarcoma	255	0.246	7.37e-05	5.9	54.9	39.2	Gain
SKCM	Skin Cutaneous Melanoma	367	0.459	1.65e-20	1.9	48.2	49.9	Gain
STAD	Stomach adenocarcinoma	413	0.531	1.83e-31	0.5	33.9	65.6	Gain
TGCT	Testicular Germ Cell Tumors	150	0.045	0.588	8.7	62.7	28.7	Neutral
THCA	Thyroid carcinoma	497	-0.009	0.842	0	97.6	2.4	Neutral
THYM	Thymoma	119	0.173	0.0601	0.8	90.8	8.4	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.267	3.35e-10	2.2	72.1	25.7	Neutral

Summary
Symbol	CHD6
Name	chromodomain helicase DNA binding protein 6
Aliases	KIAA1335; FLJ22369; dJ620E11.1; RIGB; CHD-6; ATP-dependent helicase CHD6; helicase C-terminal domain- and SN ......
Location	20q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

[ TOP ]

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.452	0	17	408	-0.061	9.31e-07	NS/NA
BRCA	Breast invasive carcinoma	-0.312	3.02e-21	83	785	-0.024	1.46e-11	NS/NA
CESC	Cervical and endocervical cancers	-0.351	2.77e-10	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.281	4.49e-07	19	297	0	0.78	NS/NA
ESCA	Esophageal carcinoma	-0.331	2.7e-06	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.351	0.00431	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.242	1.25e-08	20	522	0.062	0.0496	NS/NA
KIRC	Kidney renal clear cell carcinoma	-0.234	1.3e-05	24	319	0.156	2.09e-08	NS/NA
KIRP	Kidney renal papillary cell carcinoma	-0.268	2.9e-06	23	275	0.203	8.44e-19	Increased
LAML	Acute Myeloid Leukemia	-0.108	0.161	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	-0.101	0.0205	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.181	0.000223	41	373	-0.014	0.00517	NS/NA
LUAD	Lung adenocarcinoma	-0.402	0	21	456	0.027	0.00239	NS/NA
LUSC	Lung squamous cell carcinoma	-0.517	0	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	-0.567	0.121	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.34	2.89e-06	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.323	7.33e-06	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.327	1.34e-14	35	498	0.001	0.202	NS/NA
READ	Rectum adenocarcinoma	-0.277	0.00523	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.247	5.25e-05	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.22	1.48e-06	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.32	3.56e-10	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.556	0	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.095	0.0255	50	509	0.065	0.763	NS/NA
THYM	Thymoma	-0.4	5.94e-06	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.262	1.07e-08	34	431	-0.023	0.0226	NS/NA

Summary
Symbol	CHD6
Name	chromodomain helicase DNA binding protein 6
Aliases	KIAA1335; FLJ22369; dJ620E11.1; RIGB; CHD-6; ATP-dependent helicase CHD6; helicase C-terminal domain- and SN ......
Location	20q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA) [ TOP ]
There is no antibody staining data.

Summary
Symbol	CHD6
Name	chromodomain helicase DNA binding protein 6
Aliases	KIAA1335; FLJ22369; dJ620E11.1; RIGB; CHD-6; ATP-dependent helicase CHD6; helicase C-terminal domain- and SN ......
Location	20q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.742	NS	24476821
BRCA	Breast invasive carcinoma	521	1.78e-23	Significant	23000897
COAD	Colon adenocarcinoma	149	5.51e-10	Significant	22810696
GBM	Glioblastoma multiforme	157	0.000117	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	1.98e-15	Significant	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.00437	Significant	26536169
LGG	Brain Lower Grade Glioma	513	7.56e-07	Significant	26824661
LUAD	Lung adenocarcinoma	230	0.0126	Significant	25079552
LUSC	Lung squamous cell carcinoma	178	0.000168	Significant	22960745
OV	Ovarian serous cystadenocarcinoma	287	0.00033	Significant	21720365
PRAD	Prostate adenocarcinoma	333	0.95	NS	26544944
READ	Rectum adenocarcinoma	67	0.0261	Significant	22810696
SKCM	Skin Cutaneous Melanoma	315	0.0474	Significant	26091043
STAD	Stomach adenocarcinoma	277	1.26e-15	Significant	25079317
THCA	Thyroid carcinoma	391	0.263	NS	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	0.786	NS	23636398

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	0.765	0.236	NS
BRCA	Breast invasive carcinoma	1079	1.41	0.126	NS
CESC	Cervical and endocervical cancers	291	1.187	0.627	NS
COAD	Colon adenocarcinoma	439	1.243	0.479	NS
ESCA	Esophageal carcinoma	184	1.337	0.366	NS
GBM	Glioblastoma multiforme	158	0.733	0.226	NS
HNSC	Head and Neck squamous cell carcinoma	518	0.83	0.344	NS
KIRC	Kidney renal clear cell carcinoma	531	0.546	0.00859	Longer
KIRP	Kidney renal papillary cell carcinoma	287	1.244	0.601	NS
LAML	Acute Myeloid Leukemia	149	0.379	0.00186	Longer
LGG	Brain Lower Grade Glioma	511	0.824	0.456	NS
LIHC	Liver hepatocellular carcinoma	365	1.084	0.746	NS
LUAD	Lung adenocarcinoma	502	0.59	0.0115	Longer
LUSC	Lung squamous cell carcinoma	494	0.84	0.353	NS
OV	Ovarian serous cystadenocarcinoma	303	1.399	0.12	NS
PAAD	Pancreatic adenocarcinoma	177	0.713	0.247	NS
PCPG	Pheochromocytoma and Paraganglioma	179	597715418.102	0.156	NS
PRAD	Prostate adenocarcinoma	497	1.881	0.674	NS
READ	Rectum adenocarcinoma	159	0.637	0.514	NS
SARC	Sarcoma	259	1.387	0.294	NS
SKCM	Skin Cutaneous Melanoma	459	0.762	0.152	NS
STAD	Stomach adenocarcinoma	388	1.193	0.466	NS
TGCT	Testicular Germ Cell Tumors	134	1.118	0.937	NS
THCA	Thyroid carcinoma	500	2.293	0.308	NS
THYM	Thymoma	119	2.914	0.333	NS
UCEC	Uterine Corpus Endometrial Carcinoma	543	1.566	0.128	NS

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	-0.076	0.128	NS
BRCA	Breast invasive carcinoma	1071	0.008	0.804	NS
CESC	Cervical and endocervical cancers	167	0.019	0.807	NS
COAD	Colon adenocarcinoma	445	0.067	0.158	NS
ESCA	Esophageal carcinoma	162	0.161	0.0407	Higher
HNSC	Head and Neck squamous cell carcinoma	448	0.011	0.821	NS
KIRC	Kidney renal clear cell carcinoma	531	-0.168	0.000105	Lower
KIRP	Kidney renal papillary cell carcinoma	260	-0.01	0.876	NS
LIHC	Liver hepatocellular carcinoma	347	0.03	0.579	NS
LUAD	Lung adenocarcinoma	507	-0.1	0.0243	Lower
LUSC	Lung squamous cell carcinoma	497	-0.035	0.436	NS
OV	Ovarian serous cystadenocarcinoma	302	-0.086	0.136	NS
PAAD	Pancreatic adenocarcinoma	176	-0.047	0.536	NS
READ	Rectum adenocarcinoma	156	0.095	0.24	NS
SKCM	Skin Cutaneous Melanoma	410	-0.091	0.0654	NS
STAD	Stomach adenocarcinoma	392	0.075	0.137	NS
TGCT	Testicular Germ Cell Tumors	81	-0.318	0.00387	Lower
THCA	Thyroid carcinoma	499	-0.089	0.0465	Lower
UCEC	Uterine Corpus Endometrial Carcinoma	501	0.001	0.978	NS

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	0.053	0.387	NS
HNSC	Head and Neck squamous cell carcinoma	498	0.191	1.84e-05	Higher
KIRC	Kidney renal clear cell carcinoma	525	-0.18	3.52e-05	Lower
LGG	Brain Lower Grade Glioma	514	-0.077	0.0831	NS
LIHC	Liver hepatocellular carcinoma	366	0.018	0.731	NS
OV	Ovarian serous cystadenocarcinoma	296	0.013	0.829	NS
PAAD	Pancreatic adenocarcinoma	176	-0.064	0.399	NS
STAD	Stomach adenocarcinoma	406	-0.015	0.759	NS
UCEC	Uterine Corpus Endometrial Carcinoma	534	-0.006	0.882	NS

Summary
Symbol	CHD6
Name	chromodomain helicase DNA binding protein 6
Aliases	KIAA1335; FLJ22369; dJ620E11.1; RIGB; CHD-6; ATP-dependent helicase CHD6; helicase C-terminal domain- and SN ......
Location	20q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	CHD6
Name	chromodomain helicase DNA binding protein 6
Aliases	KIAA1335; FLJ22369; dJ620E11.1; RIGB; CHD-6; ATP-dependent helicase CHD6; helicase C-terminal domain- and SN ......
Location	20q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for CHD6.

Summary
Symbol	CHD6
Name	chromodomain helicase DNA binding protein 6
Aliases	KIAA1335; FLJ22369; dJ620E11.1; RIGB; CHD-6; ATP-dependent helicase CHD6; helicase C-terminal domain- and SN ......
Location	20q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]
There is no record for CHD6.

> Interactions from Text Mining [ TOP ]
There is no record for CHD6.