CR2Cancer

Summary
Symbol	CHD9
Name	chromodomain helicase DNA binding protein 9
Aliases	FLJ12178; KIAA0308; BC022889; AD013; CHD-9; CReMM; KISH2; PRIC320; ATP-dependent helicase CHD9; PPAR-alpha-i ......
Location	16q12.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

[ TOP ]

Domain

PF07533 BRK domain
PF00385 Chromo (CHRromatin Organisation MOdifier) domain
PF00271 Helicase conserved C-terminal domain
PF00176 SNF2 family N-terminal domain

Function

Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has DNA-dependent ATPase activity and binds to A/T-rich DNA. Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis (By similarity).

Classification

Class	Modification	Substrate	Product	PubMed
Chromatin remodelling	#	#	#	16554032

> Gene Ontology [ TOP ]
Biological Process	-
Molecular Function	GO:0004386 helicase activity
Cellular Component	-

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	R-HSA-2426168: Activation of gene expression by SREBF (SREBP) R-HSA-1368108: BMAL1 R-HSA-400253: Circadian Clock R-HSA-1266738: Developmental Biology R-HSA-535734: Fatty acid, triacylglycerol, and ketone body metabolism R-HSA-74160: Gene Expression R-HSA-212436: Generic Transcription Pathway R-HSA-1430728: Metabolism R-HSA-556833: Metabolism of lipids and lipoproteins R-HSA-1592230: Mitochondrial biogenesis R-HSA-1852241: Organelle biogenesis and maintenance R-HSA-1989781: PPARA activates gene expression R-HSA-1368082: RORA activates gene expression R-HSA-1655829: Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-400206: Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) R-HSA-2151201: Transcriptional activation of mitochondrial biogenesis R-HSA-381340: Transcriptional regulation of white adipocyte differentiation R-HSA-2032785: YAP1- and WWTR1 (TAZ)-stimulated gene expression

> KEGG and Reactome Pathway

[ TOP ]

KEGG

Reactome

R-HSA-2426168: Activation of gene expression by SREBF (SREBP)
R-HSA-1368108: BMAL1
R-HSA-400253: Circadian Clock
R-HSA-1266738: Developmental Biology
R-HSA-535734: Fatty acid, triacylglycerol, and ketone body metabolism
R-HSA-74160: Gene Expression
R-HSA-212436: Generic Transcription Pathway
R-HSA-1430728: Metabolism
R-HSA-556833: Metabolism of lipids and lipoproteins
R-HSA-1592230: Mitochondrial biogenesis
R-HSA-1852241: Organelle biogenesis and maintenance
R-HSA-1989781: PPARA activates gene expression
R-HSA-1368082: RORA activates gene expression
R-HSA-1655829: Regulation of cholesterol biosynthesis by SREBP (SREBF)
R-HSA-400206: Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
R-HSA-2151201: Transcriptional activation of mitochondrial biogenesis
R-HSA-381340: Transcriptional regulation of white adipocyte differentiation
R-HSA-2032785: YAP1- and WWTR1 (TAZ)-stimulated gene expression

Summary
Symbol	CHD9
Name	chromodomain helicase DNA binding protein 9
Aliases	FLJ12178; KIAA0308; BC022889; AD013; CHD-9; CReMM; KISH2; PRIC320; ATP-dependent helicase CHD9; PPAR-alpha-i ......
Location	16q12.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM1201025	c.8572G>T	p.G2858*	Substitution - Nonsense	Large_intestine
COSM1201024	c.8105G>T	p.G2702V	Substitution - Missense	Large_intestine
COSM4848361	c.5650G>C	p.E1884Q	Substitution - Missense	Cervix
COSM5078707	c.4209+8T>G	p.?	Unknown	Large_intestine
COSM3691043	c.4616G>A	p.C1539Y	Substitution - Missense	Large_intestine
COSM4885383	c.1325C>T	p.S442L	Substitution - Missense	Upper_aerodigestive_tract
COSM4672115	c.4849delA	p.K1618fs*3	Deletion - Frameshift	Large_intestine
COSM1629922	c.7822-5T>A	p.?	Unknown	Liver
COSM4061189	c.730T>C	p.C244R	Substitution - Missense	Stomach
COSM1248231	c.4320+8delT	p.?	Unknown	Stomach
COSM379103	c.4190G>A	p.R1397H	Substitution - Missense	Lung
COSM279877	c.7625G>T	p.R2542I	Substitution - Missense	Large_intestine
COSM3932363	c.2776G>C	p.E926Q	Substitution - Missense	Urinary_tract
COSM79642	c.4518G>T	p.G1506G	Substitution - coding silent	Ovary
COSM703470	c.1528G>C	p.E510Q	Substitution - Missense	Lung
COSM5942646	c.8137C>T	p.P2713S	Substitution - Missense	Skin
COSM1638242	c.3312T>C	p.N1104N	Substitution - coding silent	Bone
COSM703464	c.6471C>T	p.S2157S	Substitution - coding silent	Lung
COSM435379	c.226T>G	p.S76A	Substitution - Missense	Breast
COSM3510240	c.8254G>A	p.E2752K	Substitution - Missense	Skin
COSM2834883	c.4199C>T	p.T1400I	Substitution - Missense	Large_intestine
COSM1248232	c.4921G>A	p.V1641I	Substitution - Missense	Oesophagus
COSM260099	c.7162C>T	p.R2388*	Substitution - Nonsense	Large_intestine
COSM3402358	c.5515A>G	p.T1839A	Substitution - Missense	Central_nervous_system
COSM971430	c.5547T>C	p.V1849V	Substitution - coding silent	Endometrium
COSM703467	c.4688G>T	p.G1563V	Substitution - Missense	Lung
COSM1609407	c.1231C>T	p.Q411*	Substitution - Nonsense	Liver
COSM2834908	c.5779C>T	p.R1927C	Substitution - Missense	Pancreas
COSM1730121	c.7889G>A	p.R2630K	Substitution - Missense	Liver
COSM1378317	c.3348G>T	p.K1116N	Substitution - Missense	Large_intestine
COSM1302018	c.3955C>T	p.R1319*	Substitution - Nonsense	Urinary_tract
COSM25184	c.2680C>G	p.Q894E	Substitution - Missense	Lung
COSM2834946	c.7938A>T	p.A2646A	Substitution - coding silent	Stomach
COSM1378307	c.895A>C	p.N299H	Substitution - Missense	Large_intestine
COSM6016190	c.5358G>A	p.R1786R	Substitution - coding silent	Skin
COSM5983122	c.7165G>T	p.E2389*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM2834840	c.862C>T	p.Q288*	Substitution - Nonsense	Large_intestine
COSM4168586	c.7681C>T	p.R2561C	Substitution - Missense	Peritoneum
COSM4061195	c.1705A>T	p.R569W	Substitution - Missense	Stomach
COSM1718402	c.6541T>C	p.S2181P	Substitution - Missense	Skin
COSM971433	c.6549T>C	p.S2183S	Substitution - coding silent	Endometrium
COSM1378322	c.7288delA	p.R2432fs*8	Deletion - Frameshift	Large_intestine
COSM971423	c.4070G>A	p.R1357Q	Substitution - Missense	Endometrium
COSM3510225	c.395C>T	p.T132I	Substitution - Missense	Skin
COSM4439395	c.1663C>T	p.P555S	Substitution - Missense	Oesophagus
COSM971421	c.3321G>T	p.K1107N	Substitution - Missense	Endometrium
COSM5991259	c.4874A>T	p.N1625I	Substitution - Missense	Prostate
COSM5569630	c.8089A>G	p.T2697A	Substitution - Missense	Prostate
COSM2834868	c.3111T>C	p.F1037F	Substitution - coding silent	Large_intestine
COSM5913747	c.4639G>A	p.E1547K	Substitution - Missense	Skin
COSM4504689	c.6731C>T	p.S2244F	Substitution - Missense	Skin
COSM5718248	c.2050C>T	p.P684S	Substitution - Missense	Skin
COSM1729105	c.2159A>T	p.Y720F	Substitution - Missense	Liver
COSM435383	c.3223A>C	p.K1075Q	Substitution - Missense	Breast
COSM5016519	c.1077_1078insA	p.N360fs*7	Insertion - Frameshift	Kidney
COSM4061196	c.2677A>G	p.I893V	Substitution - Missense	Stomach
COSM5479140	c.4707G>A	p.Q1569Q	Substitution - coding silent	Large_intestine
COSM3421032	c.6000C>T	p.N2000N	Substitution - coding silent	Large_intestine
COSM5493433	c.2938C>A	p.L980I	Substitution - Missense	Biliary_tract
COSM5179753	c.2103delA	p.K703fs*7	Deletion - Frameshift	Large_intestine
COSM3691045	c.5223A>G	p.P1741P	Substitution - coding silent	Large_intestine
COSM4061201	c.6937G>A	p.E2313K	Substitution - Missense	Stomach
COSM356031	c.3908T>A	p.V1303D	Substitution - Missense	Lung
COSM3716950	c.8294A>G	p.N2765S	Substitution - Missense	Liver
COSM5882728	c.6530C>A	p.S2177*	Substitution - Nonsense	Soft_tissue
COSM1201020	c.6613A>C	p.K2205Q	Substitution - Missense	Large_intestine
COSM5599299	c.5461G>A	p.E1821K	Substitution - Missense	Skin
COSM3988518	c.4003A>G	p.S1335G	Substitution - Missense	Kidney
COSM4260619	c.7941T>A	p.A2647A	Substitution - coding silent	Large_intestine
COSM3510236	c.6716A>G	p.N2239S	Substitution - Missense	Skin
COSM4672110	c.2787G>A	p.T929T	Substitution - coding silent	Large_intestine
COSM4061202	c.7901G>A	p.R2634Q	Substitution - Missense	Stomach
COSM4061193	c.1491T>C	p.Y497Y	Substitution - coding silent	Stomach
COSM971436	c.7855C>T	p.L2619F	Substitution - Missense	Endometrium
COSM2834945	c.7906delA	p.S2637fs*24	Deletion - Frameshift	Large_intestine
COSM1609408	c.1452+3A>G	p.?	Unknown	Liver
COSM5219850	c.5780delG	p.R1927fs*5	Deletion - Frameshift	Breast
COSM4885766	c.3241C>T	p.R1081*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM4579082	c.189G>A	p.Q63Q	Substitution - coding silent	Bone
COSM5384989	c.7878G>A	p.E2626E	Substitution - coding silent	Skin
COSM971408	c.575C>A	p.S192Y	Substitution - Missense	Breast
COSM4061197	c.2818G>T	p.G940W	Substitution - Missense	Stomach
COSM4061191	c.911A>C	p.D304A	Substitution - Missense	Stomach
COSM279876	c.6888C>A	p.F2296L	Substitution - Missense	Large_intestine
COSM971426	c.4720C>A	p.L1574I	Substitution - Missense	Endometrium
COSM1302019	c.6295G>A	p.E2099K	Substitution - Missense	Urinary_tract
COSM1609412	c.3693A>G	p.R1231R	Substitution - coding silent	Liver
COSM703466	c.5378A>T	p.Q1793L	Substitution - Missense	Lung
COSM4061190	c.808T>A	p.F270I	Substitution - Missense	Stomach
COSM243680	c.3791G>A	p.G1264D	Substitution - Missense	Prostate
COSM1742341	c.2253G>C	p.L751F	Substitution - Missense	Urinary_tract
COSM1378313	c.2570G>A	p.G857D	Substitution - Missense	Large_intestine
COSM290360	c.2699A>G	p.Y900C	Substitution - Missense	Large_intestine
COSM4922393	c.8664A>C	p.S2888S	Substitution - coding silent	Liver
COSM2834884	c.4287G>T	p.K1429N	Substitution - Missense	Large_intestine
COSM3402357	c.4940A>T	p.Q1647L	Substitution - Missense	Central_nervous_system
COSM3818089	c.7363C>T	p.H2455Y	Substitution - Missense	Breast
COSM5620488	c.4376C>T	p.A1459V	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM6002025	c.8001T>A	p.G2667G	Substitution - coding silent	Prostate
COSM1201026	c.941A>G	p.H314R	Substitution - Missense	Large_intestine
COSM1629919	c.1694A>C	p.K565T	Substitution - Missense	Liver
COSM2151713	c.480T>A	p.H160Q	Substitution - Missense	Central_nervous_system
COSM365079	c.6961G>T	p.G2321C	Substitution - Missense	Lung
COSM3794905	c.3979G>A	p.D1327N	Substitution - Missense	Urinary_tract
COSM703465	c.6450C>T	p.S2150S	Substitution - coding silent	Lung
COSM971431	c.5665G>A	p.A1889T	Substitution - Missense	Stomach
COSM4434967	c.593A>G	p.N198S	Substitution - Missense	Oesophagus
COSM5792596	c.6849A>G	p.S2283S	Substitution - coding silent	Breast
COSM971416	c.2243G>A	p.R748Q	Substitution - Missense	Endometrium
COSM5812929	c.3486A>T	p.R1162S	Substitution - Missense	Liver
COSM2834933	c.7282A>G	p.I2428V	Substitution - Missense	Large_intestine
COSM971411	c.1164G>T	p.E388D	Substitution - Missense	Endometrium
COSM3937089	c.199G>A	p.D67N	Substitution - Missense	Oesophagus
COSM5750312	c.337G>T	p.G113C	Substitution - Missense	Stomach
COSM971432	c.5962C>T	p.R1988C	Substitution - Missense	Endometrium
COSM1378312	c.2274delT	p.F760fs*16	Deletion - Frameshift	Stomach
COSM25219	c.7922A>C	p.K2641T	Substitution - Missense	Lung
COSM256618	c.5393A>G	p.N1798S	Substitution - Missense	Large_intestine
COSM3794908	c.7475A>G	p.N2492S	Substitution - Missense	Urinary_tract
COSM3712047	c.6951C>T	p.P2317P	Substitution - coding silent	Upper_aerodigestive_tract
COSM5957177	c.5666C>T	p.A1889V	Substitution - Missense	Thyroid
COSM4968189	c.2473G>A	p.E825K	Substitution - Missense	Adrenal_gland
COSM243681	c.5332C>T	p.Q1778*	Substitution - Nonsense	Prostate
COSM4061204	c.8178G>T	p.L2726F	Substitution - Missense	Stomach
COSM3818085	c.2143G>C	p.E715Q	Substitution - Missense	Breast
COSM5813789	c.5165A>T	p.Q1722L	Substitution - Missense	Liver
COSM971405	c.218A>G	p.Q73R	Substitution - Missense	Endometrium
COSM435384	c.4893G>A	p.V1631V	Substitution - coding silent	Breast
COSM223832	c.5022G>A	p.W1674*	Substitution - Nonsense	Skin
COSM703468	c.3198G>T	p.Q1066H	Substitution - Missense	Lung
COSM4981174	c.1152A>G	p.S384S	Substitution - coding silent	Oesophagus
COSM5457512	c.3937_3938insGA	p.E1313fs*11	Insertion - Frameshift	Large_intestine
COSM1493672	c.7717-2A>G	p.?	Unknown	Kidney
COSM5655796	c.3861G>A	p.Q1287Q	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM3510231	c.3378A>T	p.G1126G	Substitution - coding silent	Skin
COSM5001166	c.410A>G	p.N137S	Substitution - Missense	Pancreas
COSM3691298	c.2046G>T	p.E682D	Substitution - Missense	Large_intestine
COSM1637931	c.3268delT	p.L1090fs*11	Deletion - Frameshift	Bone
COSM260098	c.1982C>A	p.S661Y	Substitution - Missense	Large_intestine
COSM1378308	c.1219G>A	p.E407K	Substitution - Missense	Large_intestine
COSM5695747	c.4628A>G	p.Y1543C	Substitution - Missense	Soft_tissue
COSM5124054	c.4282delA	p.K1429fs*4	Deletion - Frameshift	Large_intestine
COSM148078	c.5406G>A	p.Q1802Q	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM471814	c.6717T>C	p.N2239N	Substitution - coding silent	Kidney
COSM471813	c.5154T>G	p.V1718V	Substitution - coding silent	Kidney
COSM1324409	c.437A>T	p.H146L	Substitution - Missense	Ovary
COSM4579083	c.469G>A	p.V157M	Substitution - Missense	Bone
COSM1638240	c.668A>G	p.Q223R	Substitution - Missense	Bone
COSM3818090	c.7447G>C	p.D2483H	Substitution - Missense	Breast
COSM3754930	c.3849G>A	p.Q1283Q	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM3888645	c.842T>G	p.I281R	Substitution - Missense	Skin
COSM971427	c.4789C>T	p.Q1597*	Substitution - Nonsense	Endometrium
COSM5880834	c.5150C>A	p.A1717E	Substitution - Missense	Soft_tissue
COSM1629923	c.7822-4C>A	p.?	Unknown	Liver
COSM5920958	c.5795G>A	p.R1932K	Substitution - Missense	Skin
COSM435380	c.1288C>G	p.H430D	Substitution - Missense	Breast
COSM1637582	c.7214T>C	p.I2405T	Substitution - Missense	Bone
COSM2834906	c.5758C>T	p.R1920C	Substitution - Missense	Large_intestine
COSM2834950	c.8025C>A	p.A2675A	Substitution - coding silent	Large_intestine
COSM148078	c.5406G>A	p.Q1802Q	Substitution - coding silent	Stomach
COSM5599299	c.5461G>A	p.E1821K	Substitution - Missense	Skin
COSM971423	c.4070G>A	p.R1357Q	Substitution - Missense	Large_intestine
COSM971439	c.8328C>T	p.S2776S	Substitution - coding silent	Endometrium
COSM1609410	c.2363A>G	p.D788G	Substitution - Missense	Liver
COSM4454872	c.6002A>G	p.Y2001C	Substitution - Missense	Skin
COSM4847498	c.4585G>A	p.E1529K	Substitution - Missense	Cervix
COSM4672108	c.1737delC	p.S579fs*10	Deletion - Frameshift	Large_intestine
COSM5384986	c.2436A>G	p.L812L	Substitution - coding silent	Skin
COSM372170	c.2287-1G>T	p.?	Unknown	Lung
COSM4876747	c.624C>T	p.V208V	Substitution - coding silent	Prostate
COSM4940089	c.4269G>A	p.W1423*	Substitution - Nonsense	Liver
COSM3969588	c.7449T>A	p.D2483E	Substitution - Missense	Central_nervous_system
COSM5936194	c.992C>T	p.S331L	Substitution - Missense	Skin
COSM191154	c.8173C>A	p.L2725M	Substitution - Missense	Endometrium
COSM5664955	c.4024G>T	p.G1342C	Substitution - Missense	Soft_tissue
COSM5041215	c.1547A>G	p.K516R	Substitution - Missense	Liver
COSM2834868	c.3111T>C	p.F1037F	Substitution - coding silent	Large_intestine
COSM5603178	c.4834C>A	p.Q1612K	Substitution - Missense	Skin
COSM5599299	c.5461G>A	p.E1821K	Substitution - Missense	Skin
COSM6002140	c.5382T>C	p.R1794R	Substitution - coding silent	Prostate
COSM4510560	c.8468C>T	p.S2823F	Substitution - Missense	Skin
COSM3402360	c.5921C>T	p.A1974V	Substitution - Missense	Central_nervous_system
COSM5479138	c.3292A>G	p.I1098V	Substitution - Missense	Large_intestine
COSM971414	c.1624G>T	p.E542*	Substitution - Nonsense	Endometrium
COSM5384982	c.1824G>A	p.K608K	Substitution - coding silent	Skin
COSM1201019	c.5381G>A	p.R1794H	Substitution - Missense	Large_intestine
COSM25184	c.2680C>G	p.Q894E	Substitution - Missense	Lung
COSM389183	c.4028G>T	p.G1343V	Substitution - Missense	Lung
COSM5899130	c.7531G>A	p.E2511K	Substitution - Missense	Skin
COSM369391	c.112G>T	p.E38*	Substitution - Nonsense	Lung
COSM2834879	c.4093A>G	p.M1365V	Substitution - Missense	Large_intestine
COSM4672109	c.2273_2274insT	p.A761fs*9	Insertion - Frameshift	Large_intestine
COSM3361972	c.7677A>C	p.E2559D	Substitution - Missense	Kidney
COSM3421031	c.2782C>T	p.R928C	Substitution - Missense	Skin
COSM2834923	c.6660C>T	p.S2220S	Substitution - coding silent	Large_intestine
COSM4672117	c.5362C>T	p.L1788F	Substitution - Missense	Large_intestine
COSM3969587	c.6238C>A	p.P2080T	Substitution - Missense	Central_nervous_system
COSM5013018	c.6415G>T	p.E2139*	Substitution - Nonsense	Kidney
COSM4426437	c.8287T>A	p.S2763T	Substitution - Missense	Oesophagus
COSM5726781	c.2717G>A	p.G906D	Substitution - Missense	Skin
COSM1609410	c.2363A>G	p.D788G	Substitution - Missense	Liver
COSM4061203	c.7925C>T	p.A2642V	Substitution - Missense	Stomach
COSM50264	c.2533T>C	p.W845R	Substitution - Missense	Breast
COSM3510235	c.6062T>C	p.V2021A	Substitution - Missense	Skin
COSM5054928	c.685C>G	p.Q229E	Substitution - Missense	Stomach
COSM344446	c.6694C>T	p.Q2232*	Substitution - Nonsense	Lung
COSM3736146	c.7874G>A	p.R2625K	Substitution - Missense	Skin
COSM1629920	c.4527A>T	p.R1509R	Substitution - coding silent	Liver
COSM3361800	c.7923G>A	p.K2641K	Substitution - coding silent	Kidney
COSM4672111	c.2890C>T	p.R964*	Substitution - Nonsense	Large_intestine
COSM148078	c.5406G>A	p.Q1802Q	Substitution - coding silent	Large_intestine
COSM369275	c.2468A>T	p.E823V	Substitution - Missense	Lung
COSM3510234	c.5959C>T	p.L1987F	Substitution - Missense	Skin
COSM435387	c.8329A>G	p.T2777A	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3818091	c.7911T>G	p.S2637R	Substitution - Missense	Breast
COSM3969586	c.77C>T	p.A26V	Substitution - Missense	Central_nervous_system
COSM435381	c.1759A>G	p.K587E	Substitution - Missense	Breast
COSM971425	c.4441C>T	p.R1481W	Substitution - Missense	Endometrium
COSM3510226	c.1227C>T	p.L409L	Substitution - coding silent	Skin
COSM288806	c.8108G>A	p.G2703E	Substitution - Missense	Large_intestine
COSM3370458	c.1455T>C	p.P485P	Substitution - coding silent	Thyroid
COSM1201021	c.7703G>T	p.R2568I	Substitution - Missense	Large_intestine
COSM362764	c.5951A>G	p.Y1984C	Substitution - Missense	Lung
COSM3818089	c.7363C>T	p.H2455Y	Substitution - Missense	Skin
COSM5384988	c.4729C>T	p.P1577S	Substitution - Missense	Skin
COSM4391825	c.1456C>A	p.P486T	Substitution - Missense	Prostate
COSM4568795	c.1320T>A	p.F440L	Substitution - Missense	Skin
COSM2834930	c.7194C>T	p.L2398L	Substitution - coding silent	Prostate
COSM2834918	c.6308G>A	p.R2103H	Substitution - Missense	Large_intestine
COSM4845085	c.3847C>G	p.Q1283E	Substitution - Missense	Cervix
COSM4755394	c.5387A>T	p.N1796I	Substitution - Missense	Stomach
COSM4672114	c.4161delA	p.T1389fs*29	Deletion - Frameshift	Large_intestine
COSM5078706	c.4209+7G>A	p.?	Unknown	Large_intestine
COSM1378316	c.2974C>T	p.R992*	Substitution - Nonsense	Large_intestine
COSM3754930	c.3849G>A	p.Q1283Q	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM4612057	c.7287_7288insA	p.R2432fs*12	Insertion - Frameshift	Large_intestine
COSM5603179	c.2514C>T	p.D838D	Substitution - coding silent	Skin
COSM2834879	c.4093A>G	p.M1365V	Substitution - Missense	Upper_aerodigestive_tract
COSM2834850	c.1917A>C	p.Q639H	Substitution - Missense	Large_intestine
COSM2834884	c.4287G>T	p.K1429N	Substitution - Missense	Large_intestine
COSM3691299	c.5591T>C	p.F1864S	Substitution - Missense	Large_intestine
COSM3510237	c.7630C>T	p.R2544C	Substitution - Missense	Skin
COSM2834950	c.8025C>A	p.A2675A	Substitution - coding silent	Large_intestine
COSM2834956	c.8262A>G	p.K2754K	Substitution - coding silent	Large_intestine
COSM300748	c.3669C>T	p.Y1223Y	Substitution - coding silent	Large_intestine
COSM3402359	c.5857C>T	p.P1953S	Substitution - Missense	Central_nervous_system
COSM971411	c.1164G>T	p.E388D	Substitution - Missense	Endometrium
COSM2834957	c.8321C>A	p.S2774Y	Substitution - Missense	Large_intestine
COSM4061202	c.7901G>A	p.R2634Q	Substitution - Missense	Large_intestine
COSM5599299	c.5461G>A	p.E1821K	Substitution - Missense	Skin
COSM5509148	c.1738_1739insA	p.T582fs*6	Insertion - Frameshift	Biliary_tract
COSM1629919	c.1694A>C	p.K565T	Substitution - Missense	Liver
COSM971420	c.3061A>G	p.K1021E	Substitution - Missense	Endometrium
COSM2834867	c.2881C>T	p.R961C	Substitution - Missense	Large_intestine
COSM5124054	c.4282delA	p.K1429fs*4	Deletion - Frameshift	Large_intestine
COSM3377899	c.3404A>G	p.N1135S	Substitution - Missense	Pancreas
COSM4061198	c.2949T>A	p.C983*	Substitution - Nonsense	Stomach
COSM293294	c.3865C>A	p.Q1289K	Substitution - Missense	Large_intestine
COSM393284	c.3337A>G	p.I1113V	Substitution - Missense	Lung
COSM4595974	c.199G>C	p.D67H	Substitution - Missense	Upper_aerodigestive_tract
COSM4672120	c.7504G>T	p.D2502Y	Substitution - Missense	Large_intestine
COSM5363296	c.6225T>G	p.S2075S	Substitution - coding silent	Large_intestine
COSM971417	c.2507G>A	p.R836H	Substitution - Missense	Endometrium
COSM5453324	c.1326G>A	p.S442S	Substitution - coding silent	Large_intestine
COSM1201023	c.3214G>A	p.A1072T	Substitution - Missense	Large_intestine
COSM274533	c.8119A>C	p.N2707H	Substitution - Missense	Large_intestine
COSM304654	c.175A>C	p.T59P	Substitution - Missense	Large_intestine
COSM3421031	c.2782C>T	p.R928C	Substitution - Missense	Large_intestine
COSM1378317	c.3348G>T	p.K1116N	Substitution - Missense	Large_intestine
COSM1609409	c.1845A>G	p.I615M	Substitution - Missense	Liver
COSM971423	c.4070G>A	p.R1357Q	Substitution - Missense	Large_intestine
COSM2834946	c.7938A>T	p.A2646A	Substitution - coding silent	Large_intestine
COSM230320	c.6095C>T	p.P2032L	Substitution - Missense	Skin
COSM2834950	c.8025C>A	p.A2675A	Substitution - coding silent	Large_intestine
COSM435385	c.5796G>A	p.R1932R	Substitution - coding silent	Breast
COSM2834924	c.6771G>A	p.S2257S	Substitution - coding silent	Prostate
COSM4672106	c.1598C>T	p.A533V	Substitution - Missense	Large_intestine
COSM5384987	c.4610C>G	p.A1537G	Substitution - Missense	Skin
COSM5516735	c.2373+2T>C	p.?	Unknown	Biliary_tract
COSM3818087	c.3979G>C	p.D1327H	Substitution - Missense	Breast
COSM4898430	c.853A>C	p.S285R	Substitution - Missense	Skin
COSM1609407	c.1231C>T	p.Q411*	Substitution - Nonsense	Liver
COSM3794907	c.7009G>A	p.V2337M	Substitution - Missense	Urinary_tract
COSM3727987	c.4738A>T	p.R1580W	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4505523	c.6955C>T	p.P2319S	Substitution - Missense	Skin
COSM3667867	c.7739C>T	p.P2580L	Substitution - Missense	Liver
COSM4795036	c.7893G>A	p.R2631R	Substitution - coding silent	Liver
COSM4917011	c.6834A>C	p.K2278N	Substitution - Missense	Liver
COSM3361799	c.7683T>A	p.R2561R	Substitution - coding silent	Kidney
COSM3948586	c.6540C>T	p.S2180S	Substitution - coding silent	Ovary
COSM4612057	c.7287_7288insA	p.R2432fs*12	Insertion - Frameshift	Large_intestine
COSM4061194	c.1517G>T	p.R506M	Substitution - Missense	Stomach
COSM1735965	c.7440delA	p.I2481fs*71	Deletion - Frameshift	Central_nervous_system
COSM971422	c.4069C>T	p.R1357*	Substitution - Nonsense	Endometrium
COSM971408	c.575C>A	p.S192Y	Substitution - Missense	Endometrium
COSM971440	c.8449A>G	p.I2817V	Substitution - Missense	Endometrium
COSM4672107	c.1628G>A	p.R543H	Substitution - Missense	Large_intestine
COSM5980981	c.8065A>G	p.T2689A	Substitution - Missense	Upper_aerodigestive_tract
COSM4460701	c.1177C>G	p.Q393E	Substitution - Missense	Skin
COSM3818088	c.4234C>T	p.R1412W	Substitution - Missense	Breast
COSM1578323	c.2334A>G	p.V778V	Substitution - coding silent	Lung
COSM4536365	c.2293G>A	p.E765K	Substitution - Missense	Skin
COSM334035	c.5308G>T	p.G1770C	Substitution - Missense	Lung
COSM4438275	c.5267G>T	p.G1756V	Substitution - Missense	Oesophagus
COSM3370460	c.6729G>T	p.E2243D	Substitution - Missense	Thyroid
COSM3510233	c.5675C>T	p.S1892F	Substitution - Missense	Skin
COSM5599299	c.5461G>A	p.E1821K	Substitution - Missense	Skin
COSM3510239	c.8186G>A	p.G2729E	Substitution - Missense	Skin
COSM5479137	c.2802C>T	p.N934N	Substitution - coding silent	Large_intestine
COSM4506915	c.7385C>T	p.S2462F	Substitution - Missense	Skin
COSM4061199	c.4212G>A	p.A1404A	Substitution - coding silent	Stomach
COSM5461399	c.6769T>G	p.S2257A	Substitution - Missense	Large_intestine
COSM5702989	c.1846T>C	p.S616P	Substitution - Missense	Autonomic_ganglia
COSM3667867	c.7739C>T	p.P2580L	Substitution - Missense	Liver
COSM2834918	c.6308G>A	p.R2103H	Substitution - Missense	Large_intestine
COSM1378312	c.2274delT	p.F760fs*16	Deletion - Frameshift	Large_intestine
COSM971417	c.2507G>A	p.R836H	Substitution - Missense	Oesophagus
COSM1519435	c.3001A>G	p.R1001G	Substitution - Missense	Stomach
COSM4061200	c.5220C>T	p.A1740A	Substitution - coding silent	Stomach
COSM1629921	c.6112A>G	p.K2038E	Substitution - Missense	Liver
COSM703462	c.8524G>C	p.E2842Q	Substitution - Missense	Lung
COSM2834924	c.6771G>A	p.S2257S	Substitution - coding silent	Prostate
COSM1609412	c.3693A>G	p.R1231R	Substitution - coding silent	Liver
COSM5494693	c.4838A>G	p.D1613G	Substitution - Missense	Biliary_tract
COSM3957643	c.839A>G	p.H280R	Substitution - Missense	Lung
COSM1201018	c.4598G>A	p.R1533Q	Substitution - Missense	Large_intestine
COSM5778747	c.7836A>T	p.E2612D	Substitution - Missense	Breast
COSM4795036	c.7893G>A	p.R2631R	Substitution - coding silent	Liver
COSM4923810	c.5860A>T	p.N1954Y	Substitution - Missense	Liver
COSM1201022	c.1115G>A	p.G372D	Substitution - Missense	Large_intestine
COSM5880554	c.1858C>G	p.Q620E	Substitution - Missense	Soft_tissue
COSM1717092	c.5781C>T	p.R1927R	Substitution - coding silent	Ovary
COSM1609411	c.3331C>T	p.R1111W	Substitution - Missense	Liver
COSM399720	c.5161G>A	p.E1721K	Substitution - Missense	Lung
COSM4672118	c.5386A>G	p.N1796D	Substitution - Missense	Large_intestine
COSM4927159	c.7868T>C	p.V2623A	Substitution - Missense	Liver
COSM5507901	c.358G>C	p.D120H	Substitution - Missense	Biliary_tract
COSM3510238	c.7864C>T	p.P2622S	Substitution - Missense	Skin
COSM5783871	c.1934A>G	p.Y645C	Substitution - Missense	Breast
COSM3712047	c.6951C>T	p.P2317P	Substitution - coding silent	Upper_aerodigestive_tract
COSM5920957	c.2299C>T	p.P767S	Substitution - Missense	Skin
COSM5479139	c.4247C>A	p.S1416Y	Substitution - Missense	Large_intestine
COSM260099	c.7162C>T	p.R2388*	Substitution - Nonsense	Large_intestine
COSM3741943	c.4389A>G	p.E1463E	Substitution - coding silent	Liver
COSM1201019	c.5381G>A	p.R1794H	Substitution - Missense	Large_intestine
COSM703469	c.2789G>T	p.W930L	Substitution - Missense	Lung
COSM243680	c.3791G>A	p.G1264D	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM2834962	c.8574A>G	p.G2858G	Substitution - coding silent	Large_intestine
COSM1378312	c.2274delT	p.F760fs*16	Deletion - Frameshift	Large_intestine
COSM1378322	c.7288delA	p.R2432fs*8	Deletion - Frameshift	Stomach
COSM5612174	c.1920T>A	p.I640I	Substitution - coding silent	Adrenal_gland
COSM260100	c.8549T>G	p.I2850S	Substitution - Missense	Large_intestine
COSM3932364	c.7221A>G	p.V2407V	Substitution - coding silent	Urinary_tract
COSM5820305	c.959A>T	p.E320V	Substitution - Missense	Liver
COSM971418	c.2783G>A	p.R928H	Substitution - Missense	Endometrium
COSM971441	c.8477T>G	p.F2826C	Substitution - Missense	Endometrium
COSM1201022	c.1115G>A	p.G372D	Substitution - Missense	Pancreas
COSM3402356	c.4090A>G	p.I1364V	Substitution - Missense	Central_nervous_system
COSM2834867	c.2881C>T	p.R961C	Substitution - Missense	Large_intestine
COSM4672119	c.5963G>A	p.R1988H	Substitution - Missense	Large_intestine
COSM5434934	c.3586G>A	p.A1196T	Substitution - Missense	Oesophagus
COSM4672112	c.3936_3937insGA	p.M1316fs*8	Insertion - Frameshift	Large_intestine
COSM3370459	c.2221A>G	p.R741G	Substitution - Missense	Prostate
COSM5418070	c.4406_4407insAA	p.A1470fs*35	Insertion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM1609406	c.969G>T	p.Q323H	Substitution - Missense	Liver
COSM3510224	c.368C>T	p.P123L	Substitution - Missense	Skin
COSM5904426	c.4039C>T	p.L1347F	Substitution - Missense	Skin
COSM4501392	c.587C>T	p.S196F	Substitution - Missense	Skin
COSM41153	c.7441delA	p.I2481fs*71	Deletion - Frameshift	Central_nervous_system
COSM971442	c.8657C>T	p.S2886L	Substitution - Missense	Endometrium
COSM971412	c.1174C>A	p.H392N	Substitution - Missense	Endometrium
COSM1201027	c.2145A>C	p.E715D	Substitution - Missense	Large_intestine
COSM2834924	c.6771G>A	p.S2257S	Substitution - coding silent	Prostate
COSM3679915	c.4065G>A	p.L1355L	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM971437	c.8092G>A	p.G2698S	Substitution - Missense	Endometrium
COSM299130	c.1954A>C	p.K652Q	Substitution - Missense	Large_intestine
COSM5368920	c.1130A>T	p.H377L	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5485235	c.4651G>A	p.G1551S	Substitution - Missense	Large_intestine
COSM971428	c.4839T>G	p.D1613E	Substitution - Missense	Endometrium
COSM3402361	c.8645C>A	p.S2882Y	Substitution - Missense	Central_nervous_system
COSM3754930	c.3849G>A	p.Q1283Q	Substitution - coding silent	Large_intestine
COSM703463	c.8227A>T	p.K2743*	Substitution - Nonsense	Lung
COSM4489147	c.3439C>T	p.P1147S	Substitution - Missense	Skin
COSM971410	c.1080C>A	p.N360K	Substitution - Missense	Endometrium
COSM3719743	c.8433A>C	p.P2811P	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM1324407	c.4048A>T	p.K1350*	Substitution - Nonsense	Ovary
COSM1609409	c.1845A>G	p.I615M	Substitution - Missense	Liver
COSM5434407	c.3811G>T	p.D1271Y	Substitution - Missense	Oesophagus
COSM5920959	c.2099C>T	p.T700I	Substitution - Missense	Skin
COSM2834946	c.7938A>T	p.A2646A	Substitution - coding silent	Large_intestine
COSM4978446	c.4697G>T	p.R1566L	Substitution - Missense	Oesophagus
COSM3510232	c.3802A>T	p.T1268S	Substitution - Missense	Skin
COSM5073880	c.3680G>A	p.R1227Q	Substitution - Missense	Large_intestine
COSM1730122	c.7890G>T	p.R2630S	Substitution - Missense	Liver
COSM3672272	c.8139C>A	p.P2713P	Substitution - coding silent	Prostate
COSM25183	c.2676T>A	p.T892T	Substitution - coding silent	Kidney
COSM3402355	c.2942G>T	p.G981V	Substitution - Missense	Central_nervous_system
COSM4672113	c.3956G>A	p.R1319Q	Substitution - Missense	Large_intestine
COSM4612057	c.7287_7288insA	p.R2432fs*12	Insertion - Frameshift	Prostate
COSM4417676	c.2251T>A	p.L751M	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3888646	c.6682C>T	p.Q2228*	Substitution - Nonsense	Skin
COSM471815	c.8549T>C	p.I2850T	Substitution - Missense	Kidney
COSM971424	c.4189C>T	p.R1397C	Substitution - Missense	Endometrium
COSM3510230	c.2815C>T	p.H939Y	Substitution - Missense	Skin
COSM3370459	c.2221A>G	p.R741G	Substitution - Missense	Thyroid
COSM2834963	c.8588C>A	p.P2863H	Substitution - Missense	Large_intestine
COSM4672105	c.690A>G	p.Q230Q	Substitution - coding silent	Large_intestine
COSM4129113	c.7594C>A	p.Q2532K	Substitution - Missense	Thyroid
COSM3716950	c.8294A>G	p.N2765S	Substitution - Missense	Liver
COSM5590196	c.1217C>T	p.P406L	Substitution - Missense	Skin
COSM2151713	c.480T>A	p.H160Q	Substitution - Missense	Central_nervous_system
COSM1135800	c.6936C>T	p.S2312S	Substitution - coding silent	Kidney
COSM5781969	c.4784A>T	p.D1595V	Substitution - Missense	Breast
COSM5833098	c.159_160insTT	p.N54fs*13	Insertion - Frameshift	Breast
COSM1638241	c.3234G>A	p.M1078I	Substitution - Missense	Bone
COSM4061188	c.245T>C	p.V82A	Substitution - Missense	Stomach
COSM1324408	c.2226C>G	p.I742M	Substitution - Missense	Ovary
COSM2834923	c.6660C>T	p.S2220S	Substitution - coding silent	Upper_aerodigestive_tract
COSM3794909	c.7610G>A	p.R2537K	Substitution - Missense	Urinary_tract
COSM4998374	c.2832C>A	p.S944R	Substitution - Missense	Pancreas
COSM4986792	c.1943A>G	p.D648G	Substitution - Missense	Soft_tissue
COSM3741942	c.2434C>T	p.L812L	Substitution - coding silent	Liver
COSM971407	c.566G>A	p.G189E	Substitution - Missense	Endometrium
COSM3691040	c.76G>A	p.A26T	Substitution - Missense	Large_intestine
COSM4508185	c.7736C>T	p.P2579L	Substitution - Missense	Skin
COSM1201019	c.5381G>A	p.R1794H	Substitution - Missense	Prostate
COSM5740650	c.1619G>A	p.R540H	Substitution - Missense	Small_intestine
COSM1302020	c.6403G>C	p.D2135H	Substitution - Missense	Urinary_tract
COSM4260619	c.7941T>A	p.A2647A	Substitution - coding silent	Stomach
COSM971435	c.7374A>G	p.L2458L	Substitution - coding silent	Endometrium
COSM2834956	c.8262A>G	p.K2754K	Substitution - coding silent	Large_intestine
COSM1378310	c.1583G>A	p.R528H	Substitution - Missense	Large_intestine
COSM971413	c.1269C>T	p.F423F	Substitution - coding silent	Endometrium
COSM3691044	c.5095C>T	p.R1699*	Substitution - Nonsense	Large_intestine
COSM3510233	c.5675C>T	p.S1892F	Substitution - Missense	Skin
COSM5499263	c.8194C>T	p.L2732L	Substitution - coding silent	Biliary_tract
COSM1302021	c.7603G>A	p.E2535K	Substitution - Missense	Urinary_tract
COSM5744481	c.5819G>A	p.R1940Q	Substitution - Missense	Small_intestine
COSM1609411	c.3331C>T	p.R1111W	Substitution - Missense	Liver
COSM25171	c.3774C>T	p.T1258T	Substitution - coding silent	Skin
COSM1609408	c.1452+3A>G	p.?	Unknown	Liver
COSM5926924	c.6836G>A	p.G2279E	Substitution - Missense	Skin
COSM2834908	c.5779C>T	p.R1927C	Substitution - Missense	Large_intestine
COSM148078	c.5406G>A	p.Q1802Q	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM347557	c.5077G>A	p.E1693K	Substitution - Missense	Lung
COSM971409	c.781T>C	p.S261P	Substitution - Missense	Endometrium
COSM4499634	c.5470C>T	p.L1824F	Substitution - Missense	Skin
COSM4454674	c.554A>T	p.N185I	Substitution - Missense	Skin
COSM1201017	c.4126G>A	p.E1376K	Substitution - Missense	Large_intestine
COSM1609406	c.969G>T	p.Q323H	Substitution - Missense	Liver
COSM3794906	c.4411G>A	p.E1471K	Substitution - Missense	Urinary_tract
COSM3667926	c.4511T>G	p.V1504G	Substitution - Missense	Liver
COSM971431	c.5665G>A	p.A1889T	Substitution - Missense	Endometrium
COSM6002140	c.5382T>C	p.R1794R	Substitution - coding silent	Prostate
COSM4061192	c.1211T>G	p.L404R	Substitution - Missense	Stomach
COSM3691300	c.5945C>T	p.T1982I	Substitution - Missense	Large_intestine
COSM3361800	c.7923G>A	p.K2641K	Substitution - coding silent	Kidney
COSM118019	c.688C>T	p.Q230*	Substitution - Nonsense	Ovary
COSM3510229	c.2302T>C	p.F768L	Substitution - Missense	Skin
COSM3741944	c.6165G>T	p.E2055D	Substitution - Missense	Liver
COSM971419	c.2837A>C	p.Q946P	Substitution - Missense	Endometrium
COSM2834867	c.2881C>T	p.R961C	Substitution - Missense	Large_intestine
COSM1378322	c.7288delA	p.R2432fs*8	Deletion - Frameshift	Prostate
COSM971438	c.8146C>T	p.L2716L	Substitution - coding silent	Endometrium
COSM1378308	c.1219G>A	p.E407K	Substitution - Missense	Stomach
COSM5754869	c.2912C>T	p.A971V	Substitution - Missense	Large_intestine
COSM1378311	c.1737_1738insA	p.T582fs*6	Insertion - Frameshift	Large_intestine
COSM1644491	c.3619A>G	p.M1207V	Substitution - Missense	Salivary_gland
COSM435386	c.6485G>C	p.G2162A	Substitution - Missense	Breast
COSM971411	c.1164G>T	p.E388D	Substitution - Missense	Large_intestine
COSM4451536	c.1274A>T	p.Q425L	Substitution - Missense	Skin
COSM2834916	c.6298A>G	p.T2100A	Substitution - Missense	Large_intestine
COSM471812	c.4945G>A	p.V1649I	Substitution - Missense	Kidney
COSM2834889	c.4692G>A	p.Q1564Q	Substitution - coding silent	Stomach
COSM4834308	c.6848C>G	p.S2283*	Substitution - Nonsense	Cervix
COSM2834917	c.6307C>T	p.R2103C	Substitution - Missense	Bone
COSM1661131	c.347C>T	p.P116L	Substitution - Missense	Kidney
COSM5820909	c.7424A>G	p.Y2475C	Substitution - Missense	Liver
COSM5470533	c.8240A>G	p.D2747G	Substitution - Missense	Large_intestine
COSM971429	c.5062T>G	p.F1688V	Substitution - Missense	Endometrium
COSM3402354	c.197C>A	p.T66N	Substitution - Missense	Central_nervous_system
COSM4505091	c.6848C>T	p.S2283L	Substitution - Missense	Skin
COSM416978	c.2686A>G	p.I896V	Substitution - Missense	Urinary_tract
COSM971406	c.476A>G	p.H159R	Substitution - Missense	Endometrium
COSM3510228	c.1664C>A	p.P555H	Substitution - Missense	Skin
COSM4672116	c.5351G>A	p.R1784H	Substitution - Missense	Large_intestine
COSM3510227	c.1432C>T	p.H478Y	Substitution - Missense	Skin
COSM971431	c.5665G>A	p.A1889T	Substitution - Missense	Large_intestine
COSM971434	c.7032G>T	p.K2344N	Substitution - Missense	Endometrium
COSM3818086	c.3816A>G	p.T1272T	Substitution - coding silent	Breast
COSM5054929	c.6724C>T	p.P2242S	Substitution - Missense	Stomach
COSM5493434	c.6955delC	p.P2320fs*18	Deletion - Frameshift	Biliary_tract
COSM3937090	c.3577A>T	p.K1193*	Substitution - Nonsense	Oesophagus

> Text Mining based Variations

[ TOP ]

PMID	Variation	Cancer	Evidence
21447119	Mutation	Gastric Carcinoma; Colorectal Carcinoma	CHD1, CHD2, CHD3, CHD4, CHD7, CHD8 and CHD9 mutations were found in five, 19, three, five, seven, 10 and seven cancers, respectively.

Summary
Symbol	CHD9
Name	chromodomain helicase DNA binding protein 9
Aliases	FLJ12178; KIAA0308; BC022889; AD013; CHD-9; CReMM; KISH2; PRIC320; ATP-dependent helicase CHD9; PPAR-alpha-i ......
Location	16q12.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

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Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant
Q3L8U1	550	S	Phosphoserine	-	No	None detected
Q3L8U1	611	S	Phosphoserine	-	No	None detected
Q3L8U1	1468	S	Phosphoserine	-	No	None detected
Q3L8U1	1472	S	Phosphoserine	-	No	None detected
Q3L8U1	2026	S	Phosphoserine	-	No	None detected
Q3L8U1	2058	S	Phosphoserine	-	Yes	p.S2058C (cancer: HNSC)
Q3L8U1	2059	S	Phosphoserine	-	No	None detected
Q3L8U1	2075	S	Phosphoserine	-	No	None detected
Q3L8U1	2079	S	Phosphoserine	-	No	None detected

Summary
Symbol	CHD9
Name	chromodomain helicase DNA binding protein 9
Aliases	FLJ12178; KIAA0308; BC022889; AD013; CHD-9; CReMM; KISH2; PRIC320; ATP-dependent helicase CHD9; PPAR-alpha-i ......
Location	16q12.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

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Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	5.886	4.857	-0.81	4.24e-05	Under
BRCA	Breast invasive carcinoma	112	1100	6.704	5.549	-1.072	3.77e-38	Under
CESC	Cervical and endocervical cancers	3	306	5.745	5.39	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	5.598	4.903	-0.813	1e-09	Under
ESCA	Esophageal carcinoma	11	185	6.766	6.436	-0.387	0.091	NS
GBM	Glioblastoma multiforme	5	166	5.809	5.787	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	5.751	5.492	-0.317	0.00934	NS
KIRC	Kidney renal clear cell carcinoma	72	534	6.425	6.217	-0.284	0.000252	NS
KIRP	Kidney renal papillary cell carcinoma	32	291	6.027	5.752	-0.307	0.0249	NS
LAML	Acute Myeloid Leukemia	0	173	NA	7.88	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	6.556	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	4.409	3.939	-0.502	9.12e-05	NS
LUAD	Lung adenocarcinoma	59	517	5.821	5.352	-0.43	2.94e-07	NS
LUSC	Lung squamous cell carcinoma	51	501	5.752	5.305	-0.478	4.06e-08	NS
OV	Ovarian serous cystadenocarcinoma	0	307	NA	5.107	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	5.822	5.614	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	5.352	5.674	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	6.084	5.328	-0.751	2.32e-12	Under
READ	Rectum adenocarcinoma	10	167	5.535	4.88	-0.878	0.00123	Under
SARC	Sarcoma	2	263	4.868	5.113	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	5.243	5.58	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	6.011	5.88	-0.276	0.0192	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	4.684	NA	NA	NA
THCA	Thyroid carcinoma	59	509	6.181	5.945	-0.18	0.0179	NS
THYM	Thymoma	2	120	5.985	5.157	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	5.787	4.475	-1.397	1.25e-21	Under

> Cancer Cell Line Encyclopedia (CCLE)

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Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	9.1
Autonomic ganglia	CHP212	10.1
Autonomic ganglia	IMR32	9.9
Autonomic ganglia	KELLY	9.4
Autonomic ganglia	KPNRTBM1	10.4
Autonomic ganglia	KPNSI9S	9.3
Autonomic ganglia	KPNYN	10.4
Autonomic ganglia	MHHNB11	8.7
Autonomic ganglia	NB1	9.3
Autonomic ganglia	NH6	10.4
Autonomic ganglia	SHSY5Y	9.5
Autonomic ganglia	SIMA	9.6
Autonomic ganglia	SKNAS	9.2
Autonomic ganglia	SKNBE2	10.2
Autonomic ganglia	SKNDZ	9.5
Autonomic ganglia	SKNFI	9.1
Autonomic ganglia	SKNSH	9.3
Biliary tract	HUCCT1	7.2
Biliary tract	HUH28	8.3
Biliary tract	SNU1079	8.7
Biliary tract	SNU1196	7.7
Biliary tract	SNU245	7.6
Biliary tract	SNU308	8.6
Biliary tract	SNU478	7.6
Bone	143B	9.4
Bone	A673	9.6
Bone	CADOES1	9.4
Bone	CAL78	4
Bone	G292CLONEA141B1	8.9
Bone	HOS	9.3
Bone	HS706T	9.5
Bone	HS737T	9
Bone	HS819T	9.2
Bone	HS821T	9
Bone	HS822T	9.2
Bone	HS863T	9.1
Bone	HS870T	9.3
Bone	HS888T	9.4
Bone	MG63	9.9
Bone	MHHES1	9.4
Bone	OUMS27	9.5
Bone	RDES	9.1
Bone	SJSA1	9.9
Bone	SKES1	9.2
Bone	SKNMC	8.1
Bone	SW1353	9.3
Bone	T173	8.9
Bone	TC71	9.3
Bone	U2OS	8.4
Breast	AU565	8.6
Breast	BT20	8.6
Breast	BT474	8.7
Breast	BT483	9.3
Breast	BT549	7.8
Breast	CAL120	8.4
Breast	CAL148	6.8
Breast	CAL51	10.2
Breast	CAL851	6.9
Breast	CAMA1	9.4
Breast	DU4475	8.9
Breast	EFM192A	9.1
Breast	EFM19	12.3
Breast	EVSAT	7.9
Breast	HCC1143	8.8
Breast	HCC1187	7.9
Breast	HCC1395	9.1
Breast	HCC1419	9.1
Breast	HCC1428	9
Breast	HCC1500	9.3
Breast	HCC1569	8.1
Breast	HCC1599	8.5
Breast	HCC1806	8.7
Breast	HCC1937	9.9
Breast	HCC1954	9.2
Breast	HCC202	8.4
Breast	HCC2157	7.8
Breast	HCC2218	7.9
Breast	HCC38	9.2
Breast	HCC70	9.8
Breast	HDQP1	9.3
Breast	HMC18	8.5
Breast	HS274T	8.9
Breast	HS281T	9.3
Breast	HS343T	9
Breast	HS578T	8.8
Breast	HS606T	9.4
Breast	HS739T	9.7
Breast	HS742T	9.3
Breast	JIMT1	7.6
Breast	KPL1	8.3
Breast	MCF7	8.2
Breast	MDAMB134VI	7.9
Breast	MDAMB157	8.7
Breast	MDAMB175VII	8.8
Breast	MDAMB231	8.2
Breast	MDAMB361	8.6
Breast	MDAMB415	9.2
Breast	MDAMB436	9.1
Breast	MDAMB453	9.5
Breast	MDAMB468	8.9
Breast	SKBR3	8.6
Breast	T47D	8.8
Breast	UACC812	8.4
Breast	UACC893	8.5
Breast	YMB1	9.2
Breast	ZR751	9.2
Breast	ZR7530	9.9
Central nervous system	1321N1	9.4
Central nervous system	42MGBA	9
Central nervous system	8MGBA	9.4
Central nervous system	A172	9.5
Central nervous system	AM38	8.9
Central nervous system	BECKER	9.6
Central nervous system	CAS1	9.7
Central nervous system	CCFSTTG1	9.2
Central nervous system	D283MED	9
Central nervous system	D341MED	9.9
Central nervous system	DAOY	8.3
Central nervous system	DBTRG05MG	9
Central nervous system	DKMG	10.3
Central nervous system	GAMG	8.5
Central nervous system	GB1	8.7
Central nervous system	GI1	9.6
Central nervous system	GMS10	9.5
Central nervous system	GOS3	9.7
Central nervous system	H4	8.9
Central nervous system	HS683	9.4
Central nervous system	KALS1	9.3
Central nervous system	KG1C	9.2
Central nervous system	KNS42	9.3
Central nervous system	KNS60	8.7
Central nervous system	KNS81	9.4
Central nervous system	KS1	10
Central nervous system	LN18	10
Central nervous system	LN229	9.5
Central nervous system	M059K	8.9
Central nervous system	MOGGCCM	9.2
Central nervous system	MOGGUVW	9.1
Central nervous system	NMCG1	9.3
Central nervous system	ONS76	9.7
Central nervous system	SF126	9.2
Central nervous system	SF295	9.5
Central nervous system	SNB19	10.6
Central nervous system	SNU1105	9.1
Central nervous system	SNU201	9.1
Central nervous system	SNU466	8.9
Central nervous system	SNU489	8.1
Central nervous system	SNU626	9.3
Central nervous system	SNU738	8.2
Central nervous system	SW1088	9.4
Central nervous system	SW1783	9.2
Central nervous system	T98G	8.9
Central nervous system	TM31	8.9
Central nervous system	U118MG	8.7
Central nervous system	U138MG	9.2
Central nervous system	U251MG	10.5
Central nervous system	U87MG	9.3
Central nervous system	YH13	9.4
Central nervous system	YKG1	10
Endometrium	AN3CA	9.7
Endometrium	COLO684	8.3
Endometrium	EFE184	8
Endometrium	EN	7.9
Endometrium	ESS1	9
Endometrium	HEC108	9.9
Endometrium	HEC151	8.3
Endometrium	HEC1A	9.4
Endometrium	HEC1B	9.6
Endometrium	HEC251	9
Endometrium	HEC265	8.4
Endometrium	HEC50B	9.3
Endometrium	HEC59	8.9
Endometrium	HEC6	8.8
Endometrium	ISHIKAWAHERAKLIO02ER	9
Endometrium	JHUEM1	8.1
Endometrium	JHUEM2	8.9
Endometrium	JHUEM3	8.9
Endometrium	KLE	7.9
Endometrium	MFE280	7.3
Endometrium	MFE296	8.3
Endometrium	MFE319	8.3
Endometrium	RL952	8.2
Endometrium	SNGM	8.1
Endometrium	SNU1077	8.1
Endometrium	SNU685	8.3
Endometrium	TEN	9
Haematopoietic and lymphoid	697	9.4
Haematopoietic and lymphoid	A3KAW	9.6
Haematopoietic and lymphoid	A4FUK	9.3
Haematopoietic and lymphoid	ALLSIL	9.5
Haematopoietic and lymphoid	AML193	9.5
Haematopoietic and lymphoid	AMO1	8
Haematopoietic and lymphoid	BCP1	8.3
Haematopoietic and lymphoid	BDCM	9.2
Haematopoietic and lymphoid	BL41	9.4
Haematopoietic and lymphoid	BL70	9.6
Haematopoietic and lymphoid	BV173	8.9
Haematopoietic and lymphoid	CA46	9.7
Haematopoietic and lymphoid	CI1	8.9
Haematopoietic and lymphoid	CMK115	9.8
Haematopoietic and lymphoid	CMK86	9.9
Haematopoietic and lymphoid	CMK	9.7
Haematopoietic and lymphoid	CMLT1	9.6
Haematopoietic and lymphoid	COLO775	8.4
Haematopoietic and lymphoid	DAUDI	9.3
Haematopoietic and lymphoid	DB	9.4
Haematopoietic and lymphoid	DEL	9
Haematopoietic and lymphoid	DND41	8.8
Haematopoietic and lymphoid	DOHH2	9.1
Haematopoietic and lymphoid	EB1	9.3
Haematopoietic and lymphoid	EB2	8.9
Haematopoietic and lymphoid	EHEB	9.5
Haematopoietic and lymphoid	EJM	8.3
Haematopoietic and lymphoid	EM2	9
Haematopoietic and lymphoid	EOL1	9.2
Haematopoietic and lymphoid	F36P	9.1
Haematopoietic and lymphoid	GA10	9.6
Haematopoietic and lymphoid	GDM1	8.5
Haematopoietic and lymphoid	GRANTA519	9.7
Haematopoietic and lymphoid	HDLM2	7.5
Haematopoietic and lymphoid	HDMYZ	9.4
Haematopoietic and lymphoid	HEL9217	8.8
Haematopoietic and lymphoid	HEL	9
Haematopoietic and lymphoid	HH	8.6
Haematopoietic and lymphoid	HL60	9.4
Haematopoietic and lymphoid	HPBALL	7.4
Haematopoietic and lymphoid	HS604T	8.8
Haematopoietic and lymphoid	HS611T	9.3
Haematopoietic and lymphoid	HS616T	9.2
Haematopoietic and lymphoid	HS751T	9.1
Haematopoietic and lymphoid	HT	9.5
Haematopoietic and lymphoid	HTK	8.5
Haematopoietic and lymphoid	HUNS1	9.1
Haematopoietic and lymphoid	HUT102	9.6
Haematopoietic and lymphoid	HUT78	8.1
Haematopoietic and lymphoid	JEKO1	8.2
Haematopoietic and lymphoid	JK1	9.6
Haematopoietic and lymphoid	JM1	9
Haematopoietic and lymphoid	JURKAT	8.7
Haematopoietic and lymphoid	JURLMK1	9.3
Haematopoietic and lymphoid	JVM2	9.4
Haematopoietic and lymphoid	JVM3	9.5
Haematopoietic and lymphoid	K562	9.1
Haematopoietic and lymphoid	KARPAS299	8.8
Haematopoietic and lymphoid	KARPAS422	10.1
Haematopoietic and lymphoid	KARPAS620	9.7
Haematopoietic and lymphoid	KASUMI1	10.2
Haematopoietic and lymphoid	KASUMI2	9.6
Haematopoietic and lymphoid	KASUMI6	9.7
Haematopoietic and lymphoid	KCL22	9.3
Haematopoietic and lymphoid	KE37	9.1
Haematopoietic and lymphoid	KE97	9.1
Haematopoietic and lymphoid	KG1	9.9
Haematopoietic and lymphoid	KHM1B	8.4
Haematopoietic and lymphoid	KIJK	7.4
Haematopoietic and lymphoid	KMH2	8.1
Haematopoietic and lymphoid	KMM1	8.5
Haematopoietic and lymphoid	KMS11	8.4
Haematopoietic and lymphoid	KMS12BM	6.6
Haematopoietic and lymphoid	KMS18	9.4
Haematopoietic and lymphoid	KMS20	7.7
Haematopoietic and lymphoid	KMS21BM	8.9
Haematopoietic and lymphoid	KMS26	8.8
Haematopoietic and lymphoid	KMS27	8.4
Haematopoietic and lymphoid	KMS28BM	8.6
Haematopoietic and lymphoid	KMS34	8.5
Haematopoietic and lymphoid	KO52	9.9
Haematopoietic and lymphoid	KOPN8	7.4
Haematopoietic and lymphoid	KU812	9.2
Haematopoietic and lymphoid	KYO1	8.2
Haematopoietic and lymphoid	L1236	8.7
Haematopoietic and lymphoid	L363	9.6
Haematopoietic and lymphoid	L428	8.3
Haematopoietic and lymphoid	L540	8.6
Haematopoietic and lymphoid	LAMA84	9.4
Haematopoietic and lymphoid	LOUCY	10
Haematopoietic and lymphoid	LP1	9
Haematopoietic and lymphoid	M07E	9.9
Haematopoietic and lymphoid	MC116	9.7
Haematopoietic and lymphoid	ME1	7.9
Haematopoietic and lymphoid	MEC1	9.2
Haematopoietic and lymphoid	MEC2	9
Haematopoietic and lymphoid	MEG01	9.2
Haematopoietic and lymphoid	MHHCALL2	10
Haematopoietic and lymphoid	MHHCALL3	9.9
Haematopoietic and lymphoid	MHHCALL4	10.4
Haematopoietic and lymphoid	MINO	8.7
Haematopoietic and lymphoid	MJ	8.1
Haematopoietic and lymphoid	MM1S	8.4
Haematopoietic and lymphoid	MOLM13	8.7
Haematopoietic and lymphoid	MOLM16	8.6
Haematopoietic and lymphoid	MOLM6	9.1
Haematopoietic and lymphoid	MOLP2	6
Haematopoietic and lymphoid	MOLP8	8.9
Haematopoietic and lymphoid	MOLT13	9.7
Haematopoietic and lymphoid	MOLT16	9.4
Haematopoietic and lymphoid	MOLT4	9.3
Haematopoietic and lymphoid	MONOMAC1	9.2
Haematopoietic and lymphoid	MONOMAC6	8.2
Haematopoietic and lymphoid	MOTN1	8.4
Haematopoietic and lymphoid	MUTZ5	9.9
Haematopoietic and lymphoid	MV411	9.4
Haematopoietic and lymphoid	NALM19	8.8
Haematopoietic and lymphoid	NALM1	10.1
Haematopoietic and lymphoid	NALM6	9.9
Haematopoietic and lymphoid	NAMALWA	8.9
Haematopoietic and lymphoid	NB4	9.3
Haematopoietic and lymphoid	NCIH929	8.7
Haematopoietic and lymphoid	NCO2	9.9
Haematopoietic and lymphoid	NOMO1	8.7
Haematopoietic and lymphoid	NUDHL1	7.8
Haematopoietic and lymphoid	NUDUL1	9.8
Haematopoietic and lymphoid	OCIAML2	9
Haematopoietic and lymphoid	OCIAML3	8.5
Haematopoietic and lymphoid	OCIAML5	8.9
Haematopoietic and lymphoid	OCILY10	9.9
Haematopoietic and lymphoid	OCILY19	9
Haematopoietic and lymphoid	OCILY3	9.5
Haematopoietic and lymphoid	OCIM1	9
Haematopoietic and lymphoid	OPM2	9.8
Haematopoietic and lymphoid	P12ICHIKAWA	9.4
Haematopoietic and lymphoid	P31FUJ	9.4
Haematopoietic and lymphoid	P3HR1	9
Haematopoietic and lymphoid	PCM6	7.3
Haematopoietic and lymphoid	PEER	9.6
Haematopoietic and lymphoid	PF382	9.3
Haematopoietic and lymphoid	PFEIFFER	10.5
Haematopoietic and lymphoid	PL21	9.5
Haematopoietic and lymphoid	RAJI	9.1
Haematopoietic and lymphoid	RCHACV	9.1
Haematopoietic and lymphoid	REC1	8.3
Haematopoietic and lymphoid	REH	10.7
Haematopoietic and lymphoid	RI1	7
Haematopoietic and lymphoid	RL	9.5
Haematopoietic and lymphoid	RPMI8226	8.8
Haematopoietic and lymphoid	RPMI8402	9.2
Haematopoietic and lymphoid	RS411	9.7
Haematopoietic and lymphoid	SEM	9.6
Haematopoietic and lymphoid	SET2	9.8
Haematopoietic and lymphoid	SIGM5	9
Haematopoietic and lymphoid	SKM1	9
Haematopoietic and lymphoid	SKMM2	8.4
Haematopoietic and lymphoid	SR786	8.4
Haematopoietic and lymphoid	ST486	9.1
Haematopoietic and lymphoid	SUDHL10	8.7
Haematopoietic and lymphoid	SUDHL1	9.2
Haematopoietic and lymphoid	SUDHL4	8.5
Haematopoietic and lymphoid	SUDHL5	9.2
Haematopoietic and lymphoid	SUDHL6	9
Haematopoietic and lymphoid	SUDHL8	8.3
Haematopoietic and lymphoid	SUPB15	9.7
Haematopoietic and lymphoid	SUPHD1	8.8
Haematopoietic and lymphoid	SUPM2	8.8
Haematopoietic and lymphoid	SUPT11	8.7
Haematopoietic and lymphoid	SUPT1	9.1
Haematopoietic and lymphoid	TALL1	9.8
Haematopoietic and lymphoid	TF1	8.6
Haematopoietic and lymphoid	THP1	9.2
Haematopoietic and lymphoid	TO175T	8.9
Haematopoietic and lymphoid	TOLEDO	8.1
Haematopoietic and lymphoid	U266B1	8.7
Haematopoietic and lymphoid	U937	8.8
Haematopoietic and lymphoid	UT7	10.1
Haematopoietic and lymphoid	WSUDLCL2	8.6
Kidney	769P	9.2
Kidney	786O	8.4
Kidney	A498	9
Kidney	A704	9.1
Kidney	ACHN	9.8
Kidney	BFTC909	8.8
Kidney	CAKI1	9.4
Kidney	CAKI2	8.6
Kidney	CAL54	9.4
Kidney	KMRC1	9.2
Kidney	KMRC20	9.5
Kidney	KMRC2	9.2
Kidney	KMRC3	9.3
Kidney	OSRC2	9.4
Kidney	RCC10RGB	9.5
Kidney	SNU1272	7.8
Kidney	SNU349	8.1
Kidney	TUHR10TKB	8
Kidney	TUHR14TKB	9.8
Kidney	TUHR4TKB	8.5
Kidney	VMRCRCW	9.4
Kidney	VMRCRCZ	10
Large intestine	C2BBE1	8.2
Large intestine	CCK81	8
Large intestine	CL11	8.3
Large intestine	CL14	8
Large intestine	CL34	8.5
Large intestine	CL40	7.9
Large intestine	COLO205	8.9
Large intestine	COLO320	9.5
Large intestine	COLO678	9.3
Large intestine	CW2	5.6
Large intestine	DLD1	8.4
Large intestine	GP2D	7.9
Large intestine	HCC56	8.8
Large intestine	HCT116	8.5
Large intestine	HCT15	8.2
Large intestine	HS675T	9.1
Large intestine	HS698T	8.9
Large intestine	HT115	7.4
Large intestine	HT29	8.2
Large intestine	HT55	8.5
Large intestine	KM12	8.7
Large intestine	LOVO	8.5
Large intestine	LS1034	8.5
Large intestine	LS123	8.7
Large intestine	LS180	8.7
Large intestine	LS411N	8.4
Large intestine	LS513	8.2
Large intestine	MDST8	8.3
Large intestine	NCIH508	9
Large intestine	NCIH716	10.1
Large intestine	NCIH747	9.5
Large intestine	OUMS23	7.4
Large intestine	RCM1	8.7
Large intestine	RKO	9.6
Large intestine	SKCO1	8.4
Large intestine	SNU1040	5.8
Large intestine	SNU1197	8.3
Large intestine	SNU175	8.4
Large intestine	SNU283	7.8
Large intestine	SNU407	8
Large intestine	SNU503	9.4
Large intestine	SNU61	8.4
Large intestine	SNU81	8.5
Large intestine	SNUC1	8.3
Large intestine	SNUC2A	9.2
Large intestine	SNUC4	8
Large intestine	SNUC5	8.8
Large intestine	SW1116	7.8
Large intestine	SW1417	8
Large intestine	SW1463	7.4
Large intestine	SW403	9.4
Large intestine	SW480	7.5
Large intestine	SW48	8.7
Large intestine	SW620	9.3
Large intestine	SW837	8.3
Large intestine	SW948	8
Large intestine	T84	8.7
Liver	ALEXANDERCELLS	8.2
Liver	C3A	9.1
Liver	HEP3B217	6.4
Liver	HEPG2	8.8
Liver	HLE	9.7
Liver	HLF	9.1
Liver	HUH1	8.7
Liver	HUH6	7.9
Liver	HUH7	7.6
Liver	JHH1	8.6
Liver	JHH2	8.7
Liver	JHH4	8.9
Liver	JHH5	7.7
Liver	JHH6	8
Liver	JHH7	7.7
Liver	LI7	8.7
Liver	PLCPRF5	8.1
Liver	SKHEP1	9.3
Liver	SNU182	7.1
Liver	SNU387	9.3
Liver	SNU398	9.4
Liver	SNU423	8.1
Liver	SNU449	8.2
Liver	SNU475	8.3
Liver	SNU761	9.1
Liver	SNU878	7.7
Liver	SNU886	7.3
Lung	A549	9.3
Lung	ABC1	8.6
Lung	BEN	8.3
Lung	CAL12T	8.3
Lung	CALU1	8.1
Lung	CALU3	9.5
Lung	CALU6	9.4
Lung	CHAGOK1	9.8
Lung	COLO668	8.2
Lung	COLO699	8.8
Lung	CORL105	8.8
Lung	CORL23	8.1
Lung	CORL24	8.5
Lung	CORL279	8.1
Lung	CORL311	9.3
Lung	CORL47	7.8
Lung	CORL51	8.4
Lung	CORL88	8.8
Lung	CORL95	7.7
Lung	CPCN	9.3
Lung	DMS114	10.1
Lung	DMS153	7.8
Lung	DMS273	8.5
Lung	DMS454	8.1
Lung	DMS53	8.6
Lung	DMS79	9
Lung	DV90	8.1
Lung	EBC1	8.6
Lung	EPLC272H	7.4
Lung	HARA	8.7
Lung	HCC1171	9.4
Lung	HCC1195	7.6
Lung	HCC15	9.5
Lung	HCC2279	6.4
Lung	HCC2935	9.8
Lung	HCC33	8.8
Lung	HCC366	7.9
Lung	HCC4006	9.6
Lung	HCC44	8.8
Lung	HCC78	10.1
Lung	HCC827	8.8
Lung	HCC95	7.9
Lung	HLC1	8.2
Lung	HLFA	9.3
Lung	HS229T	9.2
Lung	HS618T	9.5
Lung	IALM	8.1
Lung	KNS62	8.9
Lung	LC1F	9.1
Lung	LC1SQSF	9.4
Lung	LCLC103H	8.8
Lung	LCLC97TM1	9.2
Lung	LK2	8.4
Lung	LOUNH91	8.7
Lung	LU65	8.7
Lung	LU99	9.1
Lung	LUDLU1	8.6
Lung	LXF289	8.7
Lung	MORCPR	8.5
Lung	NCIH1048	8.7
Lung	NCIH1092	9.7
Lung	NCIH1105	9.8
Lung	NCIH1155	9.3
Lung	NCIH1184	11
Lung	NCIH1299	8.2
Lung	NCIH1339	9.5
Lung	NCIH1341	8.7
Lung	NCIH1355	9
Lung	NCIH1373	9.3
Lung	NCIH1385	8.5
Lung	NCIH1395	9
Lung	NCIH1435	9
Lung	NCIH1436	9.2
Lung	NCIH1437	8.8
Lung	NCIH146	7.7
Lung	NCIH1563	8.3
Lung	NCIH1568	9.4
Lung	NCIH1573	9.8
Lung	NCIH1581	9.7
Lung	NCIH1618	9.3
Lung	NCIH1623	8.7
Lung	NCIH1648	9.2
Lung	NCIH1650	9.6
Lung	NCIH1651	9.7
Lung	NCIH1666	9.4
Lung	NCIH1693	8.3
Lung	NCIH1694	10.2
Lung	NCIH1703	8.8
Lung	NCIH1734	8.7
Lung	NCIH1755	9.1
Lung	NCIH1781	8.9
Lung	NCIH1792	7.9
Lung	NCIH1793	9.2
Lung	NCIH1836	8.8
Lung	NCIH1838	8.4
Lung	NCIH1869	8.4
Lung	NCIH1876	9.8
Lung	NCIH1915	9.1
Lung	NCIH1930	7.5
Lung	NCIH1944	9
Lung	NCIH1963	10.7
Lung	NCIH196	9.1
Lung	NCIH1975	9.2
Lung	NCIH2009	8.8
Lung	NCIH2023	9.6
Lung	NCIH2029	8.5
Lung	NCIH2030	9.9
Lung	NCIH2066	8
Lung	NCIH2081	8.5
Lung	NCIH2085	8.3
Lung	NCIH2087	9.2
Lung	NCIH209	9.1
Lung	NCIH2106	8.8
Lung	NCIH2110	7.9
Lung	NCIH211	8.8
Lung	NCIH2122	8.5
Lung	NCIH2126	8
Lung	NCIH2141	8.8
Lung	NCIH2170	8.5
Lung	NCIH2171	9.2
Lung	NCIH2172	8.7
Lung	NCIH2196	8.4
Lung	NCIH2227	8.9
Lung	NCIH2228	9.7
Lung	NCIH226	9.6
Lung	NCIH2286	9.4
Lung	NCIH2291	9
Lung	NCIH2342	8.6
Lung	NCIH2347	7.9
Lung	NCIH23	8
Lung	NCIH2405	9.4
Lung	NCIH2444	7.5
Lung	NCIH292	8.8
Lung	NCIH322	9
Lung	NCIH3255	7.6
Lung	NCIH358	9.7
Lung	NCIH441	9
Lung	NCIH446	8.4
Lung	NCIH460	9.4
Lung	NCIH510	8.4
Lung	NCIH520	8.9
Lung	NCIH522	9
Lung	NCIH524	9.3
Lung	NCIH526	8.5
Lung	NCIH596	8.8
Lung	NCIH647	8.7
Lung	NCIH650	8.7
Lung	NCIH661	8.5
Lung	NCIH69	7.8
Lung	NCIH727	9.1
Lung	NCIH810	7.5
Lung	NCIH82	8.6
Lung	NCIH838	9.8
Lung	NCIH841	7.9
Lung	NCIH854	8.8
Lung	NCIH889	8.9
Lung	PC14	8.3
Lung	RERFLCAD1	9.5
Lung	RERFLCAD2	9
Lung	RERFLCAI	9.2
Lung	RERFLCKJ	8.3
Lung	RERFLCMS	8.9
Lung	RERFLCSQ1	9.7
Lung	SBC5	9.8
Lung	SCLC21H	9.6
Lung	SHP77	8.5
Lung	SKLU1	8.7
Lung	SKMES1	9.4
Lung	SQ1	8
Lung	SW1271	7.8
Lung	SW1573	8.6
Lung	SW900	8
Lung	VMRCLCD	8.3
Lung	VMRCLCP	9.5
Oesophagus	COLO680N	9
Oesophagus	ECGI10	9.2
Oesophagus	KYSE140	9.6
Oesophagus	KYSE150	9.1
Oesophagus	KYSE180	8.5
Oesophagus	KYSE270	7.8
Oesophagus	KYSE30	8.6
Oesophagus	KYSE410	9
Oesophagus	KYSE450	9.1
Oesophagus	KYSE510	8.1
Oesophagus	KYSE520	8.7
Oesophagus	KYSE70	8.8
Oesophagus	OE19	7.8
Oesophagus	OE33	9.9
Oesophagus	TE10	9.3
Oesophagus	TE11	9
Oesophagus	TE14	8.5
Oesophagus	TE15	9.1
Oesophagus	TE1	8.4
Oesophagus	TE4	8.2
Oesophagus	TE5	9.3
Oesophagus	TE6	8.9
Oesophagus	TE8	9.4
Oesophagus	TE9	9.4
Oesophagus	TT	9.4
Ovary	59M	8.2
Ovary	A2780	8.9
Ovary	CAOV3	8
Ovary	CAOV4	8.5
Ovary	COLO704	9.5
Ovary	COV318	7.7
Ovary	COV362	9.1
Ovary	COV434	11.2
Ovary	COV504	9.4
Ovary	COV644	8.5
Ovary	EFO21	9.3
Ovary	EFO27	8.9
Ovary	ES2	9.4
Ovary	FUOV1	8.9
Ovary	HEYA8	8.3
Ovary	HS571T	9
Ovary	IGROV1	8.8
Ovary	JHOC5	8.2
Ovary	JHOM1	8.8
Ovary	JHOM2B	9.6
Ovary	JHOS2	9
Ovary	JHOS4	8.5
Ovary	KURAMOCHI	8.6
Ovary	MCAS	8.5
Ovary	NIHOVCAR3	7.8
Ovary	OAW28	7.2
Ovary	OAW42	7.2
Ovary	OC314	9.5
Ovary	OC316	9.3
Ovary	ONCODG1	7.7
Ovary	OV56	9.2
Ovary	OV7	7.9
Ovary	OV90	8.9
Ovary	OVCAR4	8.8
Ovary	OVCAR8	8.9
Ovary	OVISE	8.2
Ovary	OVK18	8.4
Ovary	OVKATE	9.9
Ovary	OVMANA	9.6
Ovary	OVSAHO	7.9
Ovary	OVTOKO	9.3
Ovary	RMGI	6.4
Ovary	RMUGS	8.5
Ovary	SKOV3	9
Ovary	SNU119	7.3
Ovary	SNU840	8.9
Ovary	SNU8	7.3
Ovary	TOV112D	9.5
Ovary	TOV21G	9
Ovary	TYKNU	9.1
Pancreas	ASPC1	9.1
Pancreas	BXPC3	8.5
Pancreas	CAPAN1	7.5
Pancreas	CAPAN2	9.2
Pancreas	CFPAC1	9.3
Pancreas	DANG	9
Pancreas	HPAC	8.5
Pancreas	HPAFII	8.6
Pancreas	HS766T	7.5
Pancreas	HUPT3	8.6
Pancreas	HUPT4	9
Pancreas	KCIMOH1	7.7
Pancreas	KLM1	6.4
Pancreas	KP2	9.5
Pancreas	KP3	9.8
Pancreas	KP4	10.4
Pancreas	L33	9.8
Pancreas	MIAPACA2	9.3
Pancreas	PANC0203	9.5
Pancreas	PANC0213	9.4
Pancreas	PANC0327	8.5
Pancreas	PANC0403	9.4
Pancreas	PANC0504	9.5
Pancreas	PANC0813	7.7
Pancreas	PANC1005	8.2
Pancreas	PANC1	7.9
Pancreas	PATU8902	8.4
Pancreas	PATU8988S	8.7
Pancreas	PATU8988T	8.5
Pancreas	PK1	9.3
Pancreas	PK45H	8.8
Pancreas	PK59	8.8
Pancreas	PL45	7.7
Pancreas	PSN1	8.8
Pancreas	QGP1	9.8
Pancreas	SNU213	8
Pancreas	SNU324	8.9
Pancreas	SNU410	8.4
Pancreas	SU8686	9
Pancreas	SUIT2	9.5
Pancreas	SW1990	9.3
Pancreas	T3M4	8.7
Pancreas	TCCPAN2	9
Pancreas	YAPC	9.2
Pleura	ACCMESO1	7.9
Pleura	DM3	8.5
Pleura	ISTMES1	9.2
Pleura	ISTMES2	9.9
Pleura	JL1	8.7
Pleura	MPP89	8.5
Pleura	MSTO211H	10.3
Pleura	NCIH2052	8.8
Pleura	NCIH2452	9.7
Pleura	NCIH28	9
Prostate	22RV1	8.4
Prostate	DU145	8.8
Prostate	LNCAPCLONEFGC	9.1
Prostate	MDAPCA2B	9.2
Prostate	NCIH660	8.9
Prostate	PC3	8
Prostate	VCAP	8.5
Salivary gland	A253	9
Salivary gland	YD15	8.4
Skin	A101D	8.7
Skin	A2058	8.4
Skin	A375	8.6
Skin	C32	9.6
Skin	CHL1	9.4
Skin	CJM	9.5
Skin	COLO679	9.1
Skin	COLO741	9.1
Skin	COLO783	8.5
Skin	COLO792	6.7
Skin	COLO800	9.1
Skin	COLO818	8.8
Skin	COLO829	9
Skin	COLO849	8.8
Skin	G361	8.8
Skin	GRM	7.9
Skin	HMCB	9.1
Skin	HS294T	8.5
Skin	HS600T	9
Skin	HS688AT	9.1
Skin	HS695T	9.1
Skin	HS839T	9.1
Skin	HS852T	9.7
Skin	HS895T	9.4
Skin	HS934T	9
Skin	HS936T	9.1
Skin	HS939T	9.5
Skin	HS940T	9.1
Skin	HS944T	7.9
Skin	HT144	9.2
Skin	IGR1	9.2
Skin	IGR37	8.4
Skin	IGR39	9.2
Skin	IPC298	9.6
Skin	K029AX	9.5
Skin	LOXIMVI	9
Skin	MALME3M	8.4
Skin	MDAMB435S	9.5
Skin	MELHO	9
Skin	MELJUSO	9.1
Skin	MEWO	9.4
Skin	RPMI7951	9.3
Skin	RVH421	9.4
Skin	SH4	9
Skin	SKMEL1	9.6
Skin	SKMEL24	9.2
Skin	SKMEL28	8.7
Skin	SKMEL2	9
Skin	SKMEL30	9.2
Skin	SKMEL31	9.8
Skin	SKMEL3	8.2
Skin	SKMEL5	8.4
Skin	UACC257	8.7
Skin	UACC62	9.2
Skin	WM115	9.7
Skin	WM1799	9.1
Skin	WM2664	9.2
Skin	WM793	9.2
Skin	WM88	9.2
Skin	WM983B	8.9
Small intestine	HUTU80	8.8
Soft tissue	A204	10.5
Soft tissue	G401	9.3
Soft tissue	G402	9.2
Soft tissue	GCT	8.9
Soft tissue	HS729	8.7
Soft tissue	HT1080	8.9
Soft tissue	KYM1	10.4
Soft tissue	MESSA	8.9
Soft tissue	RD	9.5
Soft tissue	RH30	7.7
Soft tissue	RH41	8.1
Soft tissue	RKN	9.2
Soft tissue	S117	9.1
Soft tissue	SJRH30	9.3
Soft tissue	SKLMS1	9.3
Soft tissue	SKUT1	9.1
Soft tissue	TE125T	9
Soft tissue	TE159T	9
Soft tissue	TE441T	9.1
Soft tissue	TE617T	10
Stomach	2313287	8.3
Stomach	AGS	7
Stomach	AZ521	8.8
Stomach	ECC10	8.8
Stomach	ECC12	8.9
Stomach	FU97	9
Stomach	GCIY	8.8
Stomach	GSS	8.9
Stomach	GSU	8.2
Stomach	HGC27	9.3
Stomach	HS746T	8.7
Stomach	HUG1N	7.9
Stomach	IM95	8.3
Stomach	KATOIII	8.3
Stomach	KE39	7.7
Stomach	LMSU	9
Stomach	MKN1	7
Stomach	MKN45	8.8
Stomach	MKN74	8.9
Stomach	MKN7	7.4
Stomach	NCCSTCK140	8.5
Stomach	NCIN87	9.1
Stomach	NUGC2	8.3
Stomach	NUGC3	8.2
Stomach	NUGC4	8.9
Stomach	OCUM1	8.5
Stomach	RERFGC1B	9.3
Stomach	SH10TC	7.6
Stomach	SNU16	8.5
Stomach	SNU1	8.8
Stomach	SNU216	7.9
Stomach	SNU520	8.8
Stomach	SNU5	8.4
Stomach	SNU601	7.7
Stomach	SNU620	8.5
Stomach	SNU668	8.9
Stomach	SNU719	8.7
Stomach	TGBC11TKB	9.3
Thyroid	8305C	8.1
Thyroid	8505C	8.6
Thyroid	BCPAP	7
Thyroid	BHT101	8.9
Thyroid	CAL62	9.5
Thyroid	CGTHW1	9.2
Thyroid	FTC133	8.5
Thyroid	FTC238	8.5
Thyroid	ML1	9.6
Thyroid	SW579	9.2
Thyroid	TT2609C02	8.9
Thyroid	TT	9.3
Upper aerodigestive tract	BHY	8.5
Upper aerodigestive tract	BICR16	7.2
Upper aerodigestive tract	BICR18	8.2
Upper aerodigestive tract	BICR22	9.2
Upper aerodigestive tract	BICR31	8.9
Upper aerodigestive tract	BICR56	8.9
Upper aerodigestive tract	BICR6	8.8
Upper aerodigestive tract	CAL27	8.3
Upper aerodigestive tract	CAL33	8.2
Upper aerodigestive tract	DETROIT562	8.5
Upper aerodigestive tract	FADU	9.7
Upper aerodigestive tract	HS840T	9.2
Upper aerodigestive tract	HSC2	9
Upper aerodigestive tract	HSC3	8.2
Upper aerodigestive tract	HSC4	9.2
Upper aerodigestive tract	PECAPJ15	9.5
Upper aerodigestive tract	PECAPJ34CLONEC12	8.7
Upper aerodigestive tract	PECAPJ41CLONED2	8.3
Upper aerodigestive tract	PECAPJ49	7.8
Upper aerodigestive tract	SCC15	9
Upper aerodigestive tract	SCC25	9.1
Upper aerodigestive tract	SCC4	9.1
Upper aerodigestive tract	SCC9	9.2
Upper aerodigestive tract	SNU1076	9
Upper aerodigestive tract	SNU1214	8.2
Upper aerodigestive tract	SNU46	8.4
Upper aerodigestive tract	SNU899	9
Upper aerodigestive tract	YD10B	9.2
Upper aerodigestive tract	YD38	8.5
Upper aerodigestive tract	YD8	8.4
Urinary tract	5637	7.1
Urinary tract	639V	8.2
Urinary tract	647V	7.2
Urinary tract	BC3C	9.2
Urinary tract	BFTC905	9.1
Urinary tract	CAL29	8.4
Urinary tract	HS172T	9.6
Urinary tract	HT1197	7.7
Urinary tract	HT1376	9.3
Urinary tract	J82	8
Urinary tract	JMSU1	8.2
Urinary tract	KMBC2	9.6
Urinary tract	KU1919	9.2
Urinary tract	RT11284	8.2
Urinary tract	RT112	8.5
Urinary tract	RT4	8.6
Urinary tract	SCABER	8.7
Urinary tract	SW1710	9
Urinary tract	SW780	9.7
Urinary tract	T24	8.8
Urinary tract	TCCSUP	8.7
Urinary tract	UMUC1	8.2
Urinary tract	UMUC3	9.3
Urinary tract	VMCUB1	9.6

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	7.7
Adrenal gland	7.9
Appendix	7.5
Bone marrow	15.5
Breast	12.1
Cerebral cortex	12
Cervix, uterine	13.6
Colon	7.5
Duodenum	5
Endometrium	14.1
Epididymis	6.9
Esophagus	7.8
Fallopian tube	12.8
Gallbladder	11.7
Heart muscle	4.2
Kidney	11
Liver	3.2
Lung	9.3
Lymph node	7.4
Ovary	13.6
Pancreas	1.2
Parathyroid gland	26.8
Placenta	11.2
Prostate	11.6
Rectum	7.9
Salivary gland	3.2
Seminal vesicle	10.8
Skeletal muscle	1.1
Skin	6.9
Small intestine	5.9
Smooth muscle	10.4
Spleen	9.9
Stomach	8.3
Testis	8.3
Thyroid gland	18.7
Tonsil	5.7
Urinary bladder	8.4

> Text Mining based Expression [ TOP ]
There is no record.

Summary
Symbol	CHD9
Name	chromodomain helicase DNA binding protein 9
Aliases	FLJ12178; KIAA0308; BC022889; AD013; CHD-9; CReMM; KISH2; PRIC320; ATP-dependent helicase CHD9; PPAR-alpha-i ......
Location	16q12.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.3	7.29e-10	29.5	51.7	18.8	Neutral
BRCA	Breast invasive carcinoma	1075	0.417	1.65e-46	55.7	30	14.2	Loss
CESC	Cervical and endocervical cancers	292	0.427	2.28e-14	19.9	68.2	12	Neutral
COAD	Colon adenocarcinoma	449	0.172	0.000251	5.6	70.2	24.3	Neutral
ESCA	Esophageal carcinoma	183	0.568	4.76e-17	28.4	47	24.6	Neutral
GBM	Glioblastoma multiforme	147	0.56	1.57e-13	22.4	74.1	3.4	Neutral
HNSC	Head and Neck squamous cell carcinoma	514	0.361	2.85e-17	18.5	60.1	21.4	Neutral
KIRC	Kidney renal clear cell carcinoma	525	0.227	1.41e-07	4.2	77.1	18.7	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	0.254	1.28e-05	2.8	44.8	52.4	Gain
LAML	Acute Myeloid Leukemia	166	0.19	0.014	1.8	98.2	0	Neutral
LGG	Brain Lower Grade Glioma	513	0.194	9.66e-06	4.1	92.4	3.5	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.505	5.74e-25	39.6	54.4	6	Loss
LUAD	Lung adenocarcinoma	512	0.467	4.7e-29	27.7	51.4	20.9	Neutral
LUSC	Lung squamous cell carcinoma	498	0.535	2.99e-38	36.9	44.2	18.9	Loss
OV	Ovarian serous cystadenocarcinoma	300	0.571	2.46e-27	64.3	27	8.7	Loss
PAAD	Pancreatic adenocarcinoma	177	0.276	0.000199	6.8	80.2	13	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	0.196	0.0126	3.7	92	4.3	Neutral
PRAD	Prostate adenocarcinoma	491	0.349	1.81e-15	22.8	74.7	2.4	Neutral
READ	Rectum adenocarcinoma	164	0.132	0.0924	8.5	65.9	25.6	Neutral
SARC	Sarcoma	255	0.369	1.17e-09	55.3	38.8	5.9	Loss
SKCM	Skin Cutaneous Melanoma	367	0.354	2.71e-12	32.2	56.7	11.2	Neutral
STAD	Stomach adenocarcinoma	413	0.389	2.19e-16	27.4	61.5	11.1	Neutral
TGCT	Testicular Germ Cell Tumors	150	0.374	2.41e-06	34	54	12	Loss
THCA	Thyroid carcinoma	497	0.023	0.605	0.4	97	2.6	Neutral
THYM	Thymoma	119	0.278	0.00217	10.9	87.4	1.7	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.431	1.09e-25	25.3	70.9	3.7	Neutral

Summary
Symbol	CHD9
Name	chromodomain helicase DNA binding protein 9
Aliases	FLJ12178; KIAA0308; BC022889; AD013; CHD-9; CReMM; KISH2; PRIC320; ATP-dependent helicase CHD9; PPAR-alpha-i ......
Location	16q12.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

[ TOP ]

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.271	1.5e-08	17	408	0.038	0.444	NS/NA
BRCA	Breast invasive carcinoma	-0.39	0	83	785	0.004	8e-10	NS/NA
CESC	Cervical and endocervical cancers	-0.254	6.73e-06	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.27	1.18e-06	19	297	-0.05	0.192	NS/NA
ESCA	Esophageal carcinoma	-0.398	1.23e-08	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.372	0.00244	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.308	3.18e-13	20	522	0.012	2.9e-10	NS/NA
KIRC	Kidney renal clear cell carcinoma	-0.226	2.61e-05	24	319	0.352	2.34e-14	Increased
KIRP	Kidney renal papillary cell carcinoma	-0.316	2.92e-08	23	275	0.008	0.00188	NS/NA
LAML	Acute Myeloid Leukemia	-0.094	0.22	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	-0.406	0	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.371	7.01e-15	41	373	0.01	3.38e-11	NS/NA
LUAD	Lung adenocarcinoma	-0.166	0.000288	21	456	0	0.611	NS/NA
LUSC	Lung squamous cell carcinoma	-0.262	2.58e-07	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	-0.75	0.0255	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.326	7.37e-06	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.299	3.46e-05	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.289	1.37e-11	35	498	0.002	0.041	NS/NA
READ	Rectum adenocarcinoma	-0.221	0.0263	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.352	5.81e-09	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.349	7.23e-15	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.314	7.74e-10	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.388	6.91e-07	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.204	1.15e-06	50	509	0.084	5.63e-07	NS/NA
THYM	Thymoma	-0.196	0.0309	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.305	2.49e-11	34	431	0.296	2.04e-17	Increased

Summary
Symbol	CHD9
Name	chromodomain helicase DNA binding protein 9
Aliases	FLJ12178; KIAA0308; BC022889; AD013; CHD-9; CReMM; KISH2; PRIC320; ATP-dependent helicase CHD9; PPAR-alpha-i ......
Location	16q12.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Level	Level Name
Adrenal gland	2	Medium
Appendix	2	Medium
Bone marrow	2	Medium
Breast	2	Medium
Bronchus	2	Medium
Caudate	1	Low
Cerebellum	2	Medium
Cerebral cortex	2	Medium
Cervix, uterine	2	Medium
Colon	2	Medium
Duodenum	2	Medium
Endometrium	2	Medium
Epididymis	2	Medium
Esophagus	1	Low
Fallopian tube	2	Medium
Gallbladder	2	Medium
Heart muscle	2	Medium
Hippocampus	1	Low
Kidney	3	High
Liver	2	Medium
Lung	2	Medium
Lymph node	1	Low
Nasopharynx	2	Medium
Oral mucosa	2	Medium
Ovary	2	Medium
Pancreas	2	Medium
Parathyroid gland	2	Medium
Placenta	3	High
Prostate	2	Medium
Rectum	2	Medium
Salivary gland	2	Medium
Seminal vesicle	2	Medium
Skeletal muscle	2	Medium
Skin	3	High
Small intestine	2	Medium
Smooth muscle	2	Medium
Soft tissue	2	Medium
Spleen	0	Not detected
Stomach	2	Medium
Testis	2	Medium
Thyroid gland	2	Medium
Tonsil	2	Medium
Urinary bladder	3	High
Vagina	2	Medium

Summary
Symbol	CHD9
Name	chromodomain helicase DNA binding protein 9
Aliases	FLJ12178; KIAA0308; BC022889; AD013; CHD-9; CReMM; KISH2; PRIC320; ATP-dependent helicase CHD9; PPAR-alpha-i ......
Location	16q12.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.292	NS	24476821
BRCA	Breast invasive carcinoma	521	0.0168	Significant	23000897
COAD	Colon adenocarcinoma	149	0.00428	Significant	22810696
GBM	Glioblastoma multiforme	157	0.000171	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	0.965	NS	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.187	NS	26536169
LGG	Brain Lower Grade Glioma	513	1.13e-14	Significant	26824661
LUAD	Lung adenocarcinoma	230	0.000625	Significant	25079552
LUSC	Lung squamous cell carcinoma	178	0.0767	NS	22960745
OV	Ovarian serous cystadenocarcinoma	287	0.149	NS	21720365
PRAD	Prostate adenocarcinoma	333	0.107	NS	26544944
READ	Rectum adenocarcinoma	67	0.141	NS	22810696
SKCM	Skin Cutaneous Melanoma	315	0.176	NS	26091043
STAD	Stomach adenocarcinoma	277	5.4e-07	Significant	25079317
THCA	Thyroid carcinoma	391	0.0408	Significant	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	1.51e-05	Significant	23636398

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	1.233	0.327	NS
BRCA	Breast invasive carcinoma	1079	1.555	0.0529	NS
CESC	Cervical and endocervical cancers	291	1.122	0.741	NS
COAD	Colon adenocarcinoma	439	1.085	0.774	NS
ESCA	Esophageal carcinoma	184	0.83	0.581	NS
GBM	Glioblastoma multiforme	158	0.658	0.107	NS
HNSC	Head and Neck squamous cell carcinoma	518	0.844	0.392	NS
KIRC	Kidney renal clear cell carcinoma	531	0.261	1.9e-08	Longer
KIRP	Kidney renal papillary cell carcinoma	287	1.01	0.982	NS
LAML	Acute Myeloid Leukemia	149	0.623	0.105	NS
LGG	Brain Lower Grade Glioma	511	0.846	0.502	NS
LIHC	Liver hepatocellular carcinoma	365	0.679	0.118	NS
LUAD	Lung adenocarcinoma	502	0.725	0.119	NS
LUSC	Lung squamous cell carcinoma	494	1.311	0.148	NS
OV	Ovarian serous cystadenocarcinoma	303	1.362	0.139	NS
PAAD	Pancreatic adenocarcinoma	177	1.139	0.649	NS
PCPG	Pheochromocytoma and Paraganglioma	179	2.596	0.256	NS
PRAD	Prostate adenocarcinoma	497	2.579	0.299	NS
READ	Rectum adenocarcinoma	159	0.308	0.0564	NS
SARC	Sarcoma	259	1.126	0.684	NS
SKCM	Skin Cutaneous Melanoma	459	0.697	0.0627	NS
STAD	Stomach adenocarcinoma	388	1.442	0.109	NS
TGCT	Testicular Germ Cell Tumors	134	666193471.824	0.291	NS
THCA	Thyroid carcinoma	500	1.892	0.596	NS
THYM	Thymoma	119	0.778	0.763	NS
UCEC	Uterine Corpus Endometrial Carcinoma	543	0.755	0.396	NS

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	-0.059	0.235	NS
BRCA	Breast invasive carcinoma	1071	-0.036	0.24	NS
CESC	Cervical and endocervical cancers	167	-0.023	0.769	NS
COAD	Colon adenocarcinoma	445	0.012	0.806	NS
ESCA	Esophageal carcinoma	162	-0.118	0.134	NS
HNSC	Head and Neck squamous cell carcinoma	448	0.009	0.848	NS
KIRC	Kidney renal clear cell carcinoma	531	-0.182	2.57e-05	Lower
KIRP	Kidney renal papillary cell carcinoma	260	-0.088	0.159	NS
LIHC	Liver hepatocellular carcinoma	347	0.004	0.947	NS
LUAD	Lung adenocarcinoma	507	-0.036	0.421	NS
LUSC	Lung squamous cell carcinoma	497	-0.029	0.523	NS
OV	Ovarian serous cystadenocarcinoma	302	0.008	0.889	NS
PAAD	Pancreatic adenocarcinoma	176	-0.038	0.612	NS
READ	Rectum adenocarcinoma	156	0.072	0.369	NS
SKCM	Skin Cutaneous Melanoma	410	-0.018	0.713	NS
STAD	Stomach adenocarcinoma	392	0.153	0.00233	Higher
TGCT	Testicular Germ Cell Tumors	81	-0.216	0.0531	NS
THCA	Thyroid carcinoma	499	-0.057	0.202	NS
UCEC	Uterine Corpus Endometrial Carcinoma	501	-0.045	0.318	NS

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	-0.121	0.0453	Lower
HNSC	Head and Neck squamous cell carcinoma	498	-0.084	0.0622	NS
KIRC	Kidney renal clear cell carcinoma	525	-0.2	3.77e-06	Lower
LGG	Brain Lower Grade Glioma	514	-0.031	0.486	NS
LIHC	Liver hepatocellular carcinoma	366	-0.156	0.00273	Lower
OV	Ovarian serous cystadenocarcinoma	296	0	0.994	NS
PAAD	Pancreatic adenocarcinoma	176	0.035	0.642	NS
STAD	Stomach adenocarcinoma	406	0.153	0.00198	Higher
UCEC	Uterine Corpus Endometrial Carcinoma	534	-0.11	0.0106	Lower

Summary
Symbol	CHD9
Name	chromodomain helicase DNA binding protein 9
Aliases	FLJ12178; KIAA0308; BC022889; AD013; CHD-9; CReMM; KISH2; PRIC320; ATP-dependent helicase CHD9; PPAR-alpha-i ......
Location	16q12.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	CHD9
Name	chromodomain helicase DNA binding protein 9
Aliases	FLJ12178; KIAA0308; BC022889; AD013; CHD-9; CReMM; KISH2; PRIC320; ATP-dependent helicase CHD9; PPAR-alpha-i ......
Location	16q12.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for CHD9.

Summary
Symbol	CHD9
Name	chromodomain helicase DNA binding protein 9
Aliases	FLJ12178; KIAA0308; BC022889; AD013; CHD-9; CReMM; KISH2; PRIC320; ATP-dependent helicase CHD9; PPAR-alpha-i ......
Location	16q12.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining [ TOP ]
There is no record for CHD9.