CR2Cancer

Summary
Symbol	DIDO1
Name	death inducer-obliterator 1
Aliases	dJ885L7.8; FLJ11265; KIAA0333; DIO-1; BYE1; C20orf158; DATF1; chromosome 20 open reading frame 158; death as ......
Location	20q13.33
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

[ TOP ]

Domain

PF00628 PHD-finger
PF07744 SPOC domain
PF07500 Transcription factor S-II (TFIIS)

Function

Putative transcription factor, weakly pro-apoptotic when overexpressed (By similarity). Tumor suppressor. Required for early embryonic stem cell development. ; FUNCTION: Isoform 2: Displaces isoform 4 at the onset of differentiation, required for repression of stemness genes.

Classification

Class	Modification	Substrate	Product	PubMed
#	#	#	#	#

> Gene Ontology [ TOP ]
Biological Process	-
Molecular Function	-
Cellular Component	GO:0005819 spindle

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	R-HSA-1640170: Cell Cycle R-HSA-1500620: Meiosis R-HSA-1221632: Meiotic synapsis

Summary
Symbol	DIDO1
Name	death inducer-obliterator 1
Aliases	dJ885L7.8; FLJ11265; KIAA0333; DIO-1; BYE1; C20orf158; DATF1; chromosome 20 open reading frame 158; death as ......
Location	20q13.33
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM1615833	c.2536G>T	p.A846S	Substitution - Missense	Liver
COSM3681227	c.6206A>C	p.D2069A	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4495451	c.4542C>T	p.F1514F	Substitution - coding silent	Skin
COSM4603233	c.4878_4879insC	p.A1627fs*53	Insertion - Frameshift	Upper_aerodigestive_tract
COSM1721203	c.6686C>T	p.S2229L	Substitution - Missense	Skin
COSM3363362	c.2301T>C	p.L767L	Substitution - coding silent	Kidney
COSM4591407	c.4872G>C	p.K1624N	Substitution - Missense	Upper_aerodigestive_tract
COSM4621525	c.1600G>A	p.D534N	Substitution - Missense	Large_intestine
COSM260420	c.3154C>T	p.R1052*	Substitution - Nonsense	Large_intestine
COSM1615831	c.5010C>T	p.P1670P	Substitution - coding silent	Liver
COSM4137120	c.5301C>T	p.H1767H	Substitution - coding silent	Ovary
COSM4883102	c.5810C>A	p.A1937D	Substitution - Missense	Upper_aerodigestive_tract
COSM1307610	c.4236G>C	p.R1412S	Substitution - Missense	Urinary_tract
COSM4100180	c.4685A>T	p.Q1562L	Substitution - Missense	Stomach
COSM4996040	c.3189G>T	p.M1063I	Substitution - Missense	Upper_aerodigestive_tract
COSM362143	c.6666G>T	p.R2222R	Substitution - coding silent	Lung
COSM1028967	c.5667C>T	p.F1889F	Substitution - coding silent	Endometrium
COSM1534244	c.5158G>A	p.E1720K	Substitution - Missense	Urinary_tract
COSM1684631	c.3862_3873del12	p.T1291_A1294delTTAA	Deletion - In frame	Kidney
COSM1028980	c.3394G>A	p.A1132T	Substitution - Missense	Endometrium
COSM4756273	c.4097A>T	p.Q1366L	Substitution - Missense	Stomach
COSM1028992	c.1622C>T	p.A541V	Substitution - Missense	Large_intestine
COSM1165740	c.4795G>T	p.G1599C	Substitution - Missense	Large_intestine
COSM5392553	c.1903G>A	p.V635M	Substitution - Missense	Skin
COSM1413013	c.5213C>T	p.P1738L	Substitution - Missense	Large_intestine
COSM6004624	c.6199T>A	p.S2067T	Substitution - Missense	Prostate
COSM1413022	c.2227C>T	p.R743C	Substitution - Missense	Large_intestine
COSM1028981	c.3218C>T	p.A1073V	Substitution - Missense	Large_intestine
COSM1713785	c.2914C>T	p.P972S	Substitution - Missense	Skin
COSM4603233	c.4878_4879insC	p.A1627fs*53	Insertion - Frameshift	Upper_aerodigestive_tract
COSM3799749	c.1052C>T	p.T351I	Substitution - Missense	Urinary_tract
COSM3707918	c.3204A>G	p.K1068K	Substitution - coding silent	Liver
COSM1615834	c.1399C>A	p.H467N	Substitution - Missense	Liver
COSM3770873	c.4746G>A	p.S1582S	Substitution - coding silent	Pancreas
COSM4382112	c.1912G>A	p.V638I	Substitution - Missense	Large_intestine
COSM5959645	c.2499C>T	p.F833F	Substitution - coding silent	Thyroid
COSM3693631	c.4896C>T	p.D1632D	Substitution - coding silent	Large_intestine
COSM4756268	c.6637G>A	p.D2213N	Substitution - Missense	Stomach
COSM724834	c.4117G>T	p.D1373Y	Substitution - Missense	Lung
COSM3548781	c.4952C>T	p.S1651L	Substitution - Missense	Skin
COSM4677508	c.2841C>T	p.S947S	Substitution - coding silent	Large_intestine
COSM4591407	c.4872G>C	p.K1624N	Substitution - Missense	Upper_aerodigestive_tract
COSM724840	c.5291C>A	p.S1764*	Substitution - Nonsense	Lung
COSM5392550	c.3571C>T	p.L1191F	Substitution - Missense	Skin
COSM3783507	c.2877C>T	p.T959T	Substitution - coding silent	Prostate
COSM1028965	c.5901C>T	p.F1967F	Substitution - coding silent	Skin
COSM5038714	c.2541_2568del28	p.H847fs*28	Deletion - Frameshift	Liver
COSM3548772	c.5870C>T	p.P1957L	Substitution - Missense	Skin
COSM2931093	c.5228delT	p.V1743fs*121	Deletion - Frameshift	Large_intestine
COSM4499064	c.5338C>T	p.P1780S	Substitution - Missense	Skin
COSM1028990	c.1866G>T	p.T622T	Substitution - coding silent	Endometrium
COSM1681833	c.3505C>A	p.P1169T	Substitution - Missense	Ovary
COSM5834006	c.1389_1390insA	p.S464fs*27	Insertion - Frameshift	Breast
COSM1028973	c.4275C>A	p.A1425A	Substitution - coding silent	Endometrium
COSM1757016	c.3809C>T	p.P1270L	Substitution - Missense	Urinary_tract
COSM5476192	c.3750C>T	p.D1250D	Substitution - coding silent	Large_intestine
COSM4677495	c.6358G>A	p.G2120S	Substitution - Missense	Large_intestine
COSM444188	c.4516G>A	p.A1506T	Substitution - Missense	Large_intestine
COSM1413008	c.6066C>T	p.G2022G	Substitution - coding silent	Large_intestine
COSM4517603	c.3813_3814GG>AA	p.V1272M	Substitution - Missense	Skin
COSM294309	c.4153T>C	p.Y1385H	Substitution - Missense	Large_intestine
COSM4624315	c.175C>T	p.L59L	Substitution - coding silent	Large_intestine
COSM3423807	c.3914C>T	p.S1305L	Substitution - Missense	Stomach
COSM1307606	c.5426C>A	p.S1809Y	Substitution - Missense	Urinary_tract
COSM1757015	c.4470G>C	p.K1490N	Substitution - Missense	Urinary_tract
COSM3548770	c.6020C>T	p.S2007L	Substitution - Missense	Prostate
COSM4134755	c.1272G>A	p.A424A	Substitution - coding silent	Thyroid
COSM4591407	c.4872G>C	p.K1624N	Substitution - Missense	Upper_aerodigestive_tract
COSM4624315	c.175C>T	p.L59L	Substitution - coding silent	Large_intestine
COSM724833	c.3645G>A	p.R1215R	Substitution - coding silent	Lung
COSM1250077	c.4618C>T	p.Q1540*	Substitution - Nonsense	Oesophagus
COSM3841467	c.1691G>C	p.R564T	Substitution - Missense	Breast
COSM5755626	c.28G>A	p.E10K	Substitution - Missense	Large_intestine
COSM5506013	c.4387C>T	p.P1463S	Substitution - Missense	Biliary_tract
COSM5554644	c.4396G>A	p.G1466R	Substitution - Missense	Prostate
COSM3548770	c.6020C>T	p.S2007L	Substitution - Missense	Skin
COSM1203593	c.6512G>A	p.R2171H	Substitution - Missense	Large_intestine
COSM1413014	c.5206C>T	p.L1736F	Substitution - Missense	Large_intestine
COSM3972661	c.5316G>A	p.P1772P	Substitution - coding silent	Central_nervous_system
COSM3758728	c.4932C>T	p.P1644P	Substitution - coding silent	Large_intestine
COSM2931066	c.6119G>A	p.R2040H	Substitution - Missense	Central_nervous_system
COSM3911757	c.6428C>T	p.S2143F	Substitution - Missense	Skin
COSM4843656	c.6127G>A	p.E2043K	Substitution - Missense	Cervix
COSM379270	c.663C>T	p.N221N	Substitution - coding silent	Lung
COSM4481711	c.2535C>T	p.R845R	Substitution - coding silent	Skin
COSM4950262	c.2612_2613insA	p.Q872fs*8	Insertion - Frameshift	Liver
COSM3379109	c.2067C>T	p.S689S	Substitution - coding silent	Pancreas
COSM4591406	c.4867G>A	p.E1623K	Substitution - Missense	Upper_aerodigestive_tract
COSM1413027	c.1681C>T	p.P561S	Substitution - Missense	Large_intestine
COSM1723061	c.4927_4928insC	p.R1643fs*37	Insertion - Frameshift	Large_intestine
COSM5964200	c.5562G>A	p.E1854E	Substitution - coding silent	Breast
COSM302054	c.6228C>T	p.H2076H	Substitution - coding silent	Central_nervous_system
COSM333176	c.250C>T	p.R84C	Substitution - Missense	Lung
COSM4100213	c.792C>T	p.Y264Y	Substitution - coding silent	Stomach
COSM133407	c.3610_3611AA>GC	p.N1204A	Substitution - Missense	Ovary
COSM4591406	c.4867G>A	p.E1623K	Substitution - Missense	Upper_aerodigestive_tract
COSM4911399	c.1655C>T	p.P552L	Substitution - Missense	Liver
COSM1166149	c.6357C>T	p.R2119R	Substitution - coding silent	Large_intestine
COSM1028965	c.5901C>T	p.F1967F	Substitution - coding silent	Endometrium
COSM1130582	c.2892C>T	p.S964S	Substitution - coding silent	Skin
COSM1713782	c.4037C>T	p.P1346L	Substitution - Missense	Skin
COSM4100205	c.943A>G	p.I315V	Substitution - Missense	Stomach
COSM160424	c.5239C>G	p.Q1747E	Substitution - Missense	Lung
COSM3371751	c.664G>A	p.D222N	Substitution - Missense	Large_intestine
COSM1166149	c.6357C>T	p.R2119R	Substitution - coding silent	Large_intestine
COSM106611	c.4008C>T	p.P1336P	Substitution - coding silent	Skin
COSM371126	c.1145T>G	p.L382R	Substitution - Missense	Lung
COSM2931064	c.6161C>T	p.A2054V	Substitution - Missense	Stomach
COSM4802465	c.4581G>A	p.S1527S	Substitution - coding silent	Liver
COSM1534243	c.4751G>A	p.R1584H	Substitution - Missense	Oesophagus
COSM1172738	c.6596G>A	p.R2199Q	Substitution - Missense	Large_intestine
COSM724838	c.4552G>A	p.D1518N	Substitution - Missense	Lung
COSM459705	c.5700G>C	p.L1900L	Substitution - coding silent	Cervix
COSM3389888	c.3286A>T	p.R1096W	Substitution - Missense	Pancreas
COSM5707509	c.3356T>A	p.L1119Q	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM301526	c.2755_2756GC>AT	p.A919>?	Complex	Large_intestine
COSM4642455	c.6146C>T	p.A2049V	Substitution - Missense	Large_intestine
COSM1578837	c.4066G>T	p.A1356S	Substitution - Missense	Meninges
COSM4100190	c.3785C>T	p.P1262L	Substitution - Missense	Stomach
COSM2931057	c.6319G>T	p.G2107C	Substitution - Missense	Lung
COSM3371749	c.5019G>C	p.P1673P	Substitution - coding silent	Thyroid
COSM3911759	c.5543C>T	p.P1848L	Substitution - Missense	Skin
COSM3548777	c.5339C>G	p.P1780R	Substitution - Missense	Skin
COSM4100201	c.1477G>A	p.G493R	Substitution - Missense	Stomach
COSM5392548	c.3951C>T	p.I1317I	Substitution - coding silent	Skin
COSM3548825	c.88C>T	p.R30*	Substitution - Nonsense	Skin
COSM1615837	c.128C>T	p.A43V	Substitution - Missense	Liver
COSM5802596	c.5234delG	p.G1745fs*119	Deletion - Frameshift	Breast
COSM5639790	c.5973A>G	p.G1991G	Substitution - coding silent	Oesophagus
COSM1028969	c.5190C>T	p.G1730G	Substitution - coding silent	Endometrium
COSM724842	c.5546A>T	p.H1849L	Substitution - Missense	Lung
COSM1029001	c.172G>T	p.G58C	Substitution - Missense	Endometrium
COSM4929842	c.2573-2A>T	p.?	Unknown	Liver
COSM390189	c.483G>C	p.L161F	Substitution - Missense	Lung
COSM5966784	c.883G>T	p.D295Y	Substitution - Missense	Adrenal_gland
COSM4787512	c.2006A>G	p.Q669R	Substitution - Missense	Liver
COSM4134750	c.5388G>C	p.P1796P	Substitution - coding silent	Thyroid
COSM3405266	c.4988C>T	p.P1663L	Substitution - Missense	Central_nervous_system
COSM4100182	c.4521C>T	p.V1507V	Substitution - coding silent	Stomach
COSM4850748	c.4480G>C	p.E1494Q	Substitution - Missense	Cervix
COSM3548783	c.4787C>T	p.S1596F	Substitution - Missense	Skin
COSM4800152	c.2959G>C	p.D987H	Substitution - Missense	Liver
COSM1534249	c.5869C>T	p.P1957S	Substitution - Missense	Skin
COSM3548785	c.4368C>T	p.S1456S	Substitution - coding silent	Skin
COSM109496	c.3989C>T	p.P1330L	Substitution - Missense	Skin
COSM444190	c.1631T>C	p.M544T	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4677499	c.5591C>T	p.T1864M	Substitution - Missense	Large_intestine
COSM5506012	c.4927C>T	p.R1643C	Substitution - Missense	Biliary_tract
COSM724825	c.1860G>T	p.A620A	Substitution - coding silent	Lung
COSM2931223	c.1425_1426insA	p.E476fs*15	Insertion - Frameshift	Large_intestine
COSM1483830	c.3482T>G	p.L1161R	Substitution - Missense	Breast
COSM1250076	c.5414G>A	p.G1805E	Substitution - Missense	Oesophagus
COSM724843	c.5611G>A	p.E1871K	Substitution - Missense	Lung
COSM4500921	c.5769C>T	p.F1923F	Substitution - coding silent	Skin
COSM4425641	c.862T>C	p.C288R	Substitution - Missense	Oesophagus
COSM5894078	c.4072C>T	p.P1358S	Substitution - Missense	Skin
COSM5723153	c.6713C>T	p.S2238L	Substitution - Missense	Skin
COSM3758729	c.4702A>G	p.T1568A	Substitution - Missense	Large_intestine
COSM3707921	c.2917A>G	p.S973G	Substitution - Missense	Liver
COSM4293948	c.4924A>C	p.T1642P	Substitution - Missense	Upper_aerodigestive_tract
COSM1681832	c.3559C>T	p.P1187S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3548790	c.3802C>T	p.P1268S	Substitution - Missense	Skin
COSM70449	c.998C>T	p.A333V	Substitution - Missense	Ovary
COSM1413006	c.6349C>T	p.R2117C	Substitution - Missense	Large_intestine
COSM2931087	c.5320C>T	p.P1774S	Substitution - Missense	Skin
COSM724828	c.2630C>T	p.S877F	Substitution - Missense	Skin
COSM4134759	c.1140G>A	p.K380K	Substitution - coding silent	Thyroid
COSM1028994	c.1502G>C	p.S501T	Substitution - Missense	Endometrium
COSM4820745	c.2071G>C	p.D691H	Substitution - Missense	Cervix
COSM3758727	c.5682G>A	p.R1894R	Substitution - coding silent	Large_intestine
COSM3548770	c.6020C>T	p.S2007L	Substitution - Missense	Prostate
COSM3548773	c.5824C>T	p.P1942S	Substitution - Missense	Skin
COSM4484555	c.2823C>T	p.S941S	Substitution - coding silent	Skin
COSM1413007	c.6258G>T	p.R2086S	Substitution - Missense	Large_intestine
COSM4677533	c.469G>A	p.D157N	Substitution - Missense	Large_intestine
COSM4765817	c.2614_2615insA	p.L874fs*6	Insertion - Frameshift	Stomach
COSM3972662	c.2013G>A	p.R671R	Substitution - coding silent	Central_nervous_system
COSM3972660	c.5347G>A	p.E1783K	Substitution - Missense	Central_nervous_system
COSM5723153	c.6713C>T	p.S2238L	Substitution - Missense	Skin
COSM3548769	c.6152C>T	p.S2051F	Substitution - Missense	Skin
COSM269013	c.633C>T	p.G211G	Substitution - coding silent	Large_intestine
COSM342371	c.2511G>C	p.L837F	Substitution - Missense	Lung
COSM4137121	c.117C>T	p.G39G	Substitution - coding silent	Ovary
COSM5674883	c.3724T>C	p.S1242P	Substitution - Missense	Soft_tissue
COSM4924973	c.4531A>G	p.M1511V	Substitution - Missense	Liver
COSM1172738	c.6596G>A	p.R2199Q	Substitution - Missense	Oesophagus
COSM1028997	c.1083C>T	p.S361S	Substitution - coding silent	Endometrium
COSM331949	c.3660G>T	p.P1220P	Substitution - coding silent	Lung
COSM3758729	c.4702A>G	p.T1568A	Substitution - Missense	Large_intestine
COSM3911758	c.6291G>A	p.E2097E	Substitution - coding silent	Skin
COSM333636	c.5969G>A	p.G1990D	Substitution - Missense	Lung
COSM1250078	c.1087G>T	p.D363Y	Substitution - Missense	Oesophagus
COSM4100209	c.878A>G	p.H293R	Substitution - Missense	Stomach
COSM3548770	c.6020C>T	p.S2007L	Substitution - Missense	Prostate
COSM5057489	c.4257C>T	p.A1419A	Substitution - coding silent	Stomach
COSM5800238	c.5148A>C	p.A1716A	Substitution - coding silent	Breast
COSM444188	c.4516G>A	p.A1506T	Substitution - Missense	Large_intestine
COSM1029000	c.184C>T	p.R62W	Substitution - Missense	Endometrium
COSM724831	c.3439G>T	p.G1147C	Substitution - Missense	Lung
COSM1168959	c.500G>A	p.R167H	Substitution - Missense	Pancreas
COSM2931138	c.3561G>A	p.P1187P	Substitution - coding silent	Stomach
COSM149207	c.1666G>A	p.A556T	Substitution - Missense	Stomach
COSM226848	c.5500C>T	p.P1834S	Substitution - Missense	Skin
COSM4609564	c.32A>T	p.E11V	Substitution - Missense	Adrenal_gland
COSM4775659	c.6165C>T	p.P2055P	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM1681835	c.436G>T	p.D146Y	Substitution - Missense	Prostate
COSM1190307	c.4061T>G	p.V1354G	Substitution - Missense	Lung
COSM1615831	c.5010C>T	p.P1670P	Substitution - coding silent	Liver
COSM4100185	c.4351G>T	p.D1451Y	Substitution - Missense	Stomach
COSM3841464	c.3192G>A	p.Q1064Q	Substitution - coding silent	Breast
COSM4677501	c.5023C>T	p.Q1675*	Substitution - Nonsense	Large_intestine
COSM371125	c.4749A>T	p.A1583A	Substitution - coding silent	Lung
COSM4677514	c.2043T>G	p.I681M	Substitution - Missense	Large_intestine
COSM4802465	c.4581G>A	p.S1527S	Substitution - coding silent	Liver
COSM4496891	c.4850C>T	p.S1617F	Substitution - Missense	Skin
COSM6004625	c.4156G>A	p.D1386N	Substitution - Missense	Prostate
COSM5471246	c.160C>T	p.Q54*	Substitution - Nonsense	Large_intestine
COSM1723061	c.4927_4928insC	p.R1643fs*37	Insertion - Frameshift	Thyroid
COSM1250074	c.1359G>A	p.P453P	Substitution - coding silent	Oesophagus
COSM3548787	c.4044C>T	p.T1348T	Substitution - coding silent	Skin
COSM4500882	c.5758C>T	p.P1920S	Substitution - Missense	Skin
COSM5476191	c.4800C>T	p.L1600L	Substitution - coding silent	Large_intestine
COSM364558	c.3957G>A	p.Q1319Q	Substitution - coding silent	Lung
COSM724837	c.4413C>T	p.S1471S	Substitution - coding silent	Lung
COSM1615834	c.1399C>A	p.H467N	Substitution - Missense	Liver
COSM5551701	c.5165A>G	p.D1722G	Substitution - Missense	Prostate
COSM6017981	c.5212C>T	p.P1738S	Substitution - Missense	Skin
COSM4611938	c.1715delC	p.S572fs*67	Deletion - Frameshift	Large_intestine
COSM1190308	c.1136A>T	p.K379M	Substitution - Missense	Lung
COSM3363364	c.2163C>T	p.Y721Y	Substitution - coding silent	Kidney
COSM5775643	c.399G>A	p.K133K	Substitution - coding silent	Breast
COSM1307609	c.4330C>T	p.L1444L	Substitution - coding silent	Urinary_tract
COSM4581964	c.133G>T	p.A45S	Substitution - Missense	Bone
COSM1250080	c.523G>A	p.E175K	Substitution - Missense	Oesophagus
COSM3548778	c.5308A>G	p.N1770D	Substitution - Missense	Skin
COSM2931086	c.5339C>T	p.P1780L	Substitution - Missense	Skin
COSM3548780	c.4983C>T	p.P1661P	Substitution - coding silent	Skin
COSM4549473	c.4739G>A	p.R1580K	Substitution - Missense	Skin
COSM4440603	c.6101delC	p.P2034fs*>207	Deletion - Frameshift	Large_intestine
COSM444189	c.3345+1G>C	p.?	Unknown	Breast
COSM3841481	c.365G>C	p.R122T	Substitution - Missense	Breast
COSM3841463	c.4152A>G	p.P1384P	Substitution - coding silent	Breast
COSM1615833	c.2536G>T	p.A846S	Substitution - Missense	Liver
COSM5723153	c.6713C>T	p.S2238L	Substitution - Missense	Skin
COSM1713780	c.6665G>A	p.R2222Q	Substitution - Missense	Skin
COSM724826	c.2104A>G	p.I702V	Substitution - Missense	Lung
COSM127803	c.1740A>C	p.T580T	Substitution - coding silent	Skin
COSM127803	c.1740A>C	p.T580T	Substitution - coding silent	Thyroid
COSM4293948	c.4924A>C	p.T1642P	Substitution - Missense	Upper_aerodigestive_tract
COSM1028998	c.907C>T	p.R303*	Substitution - Nonsense	Endometrium
COSM4677537	c.338_339insG	p.S114fs*7	Insertion - Frameshift	Large_intestine
COSM319882	c.3750C>G	p.D1250E	Substitution - Missense	Lung
COSM1681830	c.4167G>T	p.E1389D	Substitution - Missense	Breast
COSM4591406	c.4867G>A	p.E1623K	Substitution - Missense	Upper_aerodigestive_tract
COSM3740223	c.2865C>T	p.S955S	Substitution - coding silent	Liver
COSM1028978	c.3881C>A	p.A1294E	Substitution - Missense	Endometrium
COSM1713785	c.2914C>T	p.P972S	Substitution - Missense	Skin
COSM74377	c.1979G>A	p.S660N	Substitution - Missense	Ovary
COSM1413024	c.1991C>T	p.S664L	Substitution - Missense	Large_intestine
COSM4756269	c.6490G>A	p.D2164N	Substitution - Missense	Stomach
COSM4603233	c.4878_4879insC	p.A1627fs*53	Insertion - Frameshift	Upper_aerodigestive_tract
COSM3963763	c.1940C>T	p.P647L	Substitution - Missense	Lung
COSM5474298	c.243G>A	p.A81A	Substitution - coding silent	Large_intestine
COSM149206	c.2436G>A	p.E812E	Substitution - coding silent	Stomach
COSM3548798	c.2380C>T	p.P794S	Substitution - Missense	Skin
COSM5930010	c.6143C>T	p.S2048F	Substitution - Missense	Skin
COSM4293948	c.4924A>C	p.T1642P	Substitution - Missense	Upper_aerodigestive_tract
COSM4500740	c.5727C>T	p.P1909P	Substitution - coding silent	Skin
COSM3379109	c.2067C>T	p.S689S	Substitution - coding silent	Pancreas
COSM724830	c.2761C>T	p.H921Y	Substitution - Missense	Lung
COSM4603233	c.4878_4879insC	p.A1627fs*53	Insertion - Frameshift	Upper_aerodigestive_tract
COSM5451587	c.5538G>T	p.K1846N	Substitution - Missense	Large_intestine
COSM354759	c.239T>G	p.I80S	Substitution - Missense	Lung
COSM1029000	c.184C>T	p.R62W	Substitution - Missense	Large_intestine
COSM3371751	c.664G>A	p.D222N	Substitution - Missense	Thyroid
COSM3548776	c.5359G>A	p.A1787T	Substitution - Missense	Skin
COSM4913174	c.5510T>G	p.V1837G	Substitution - Missense	Liver
COSM5723153	c.6713C>T	p.S2238L	Substitution - Missense	Skin
COSM280386	c.3393C>T	p.V1131V	Substitution - coding silent	Large_intestine
COSM1307612	c.2496C>T	p.V832V	Substitution - coding silent	Urinary_tract
COSM5494119	c.6361C>T	p.R2121*	Substitution - Nonsense	Biliary_tract
COSM4591406	c.4867G>A	p.E1623K	Substitution - Missense	Upper_aerodigestive_tract
COSM3548800	c.1910C>T	p.A637V	Substitution - Missense	Skin
COSM6017984	c.2931A>T	p.T977T	Substitution - coding silent	Skin
COSM1250073	c.5372G>C	p.G1791A	Substitution - Missense	Oesophagus
COSM1713785	c.2914C>T	p.P972S	Substitution - Missense	Skin
COSM3379109	c.2067C>T	p.S689S	Substitution - coding silent	Pancreas
COSM5471245	c.5977C>T	p.R1993W	Substitution - Missense	Large_intestine
COSM3548805	c.1665C>T	p.S555S	Substitution - coding silent	Skin
COSM1307607	c.4862C>T	p.S1621L	Substitution - Missense	Urinary_tract
COSM1713786	c.1702C>T	p.P568S	Substitution - Missense	Skin
COSM3693630	c.6101C>T	p.P2034L	Substitution - Missense	Large_intestine
COSM3933908	c.1807A>C	p.T603P	Substitution - Missense	Urinary_tract
COSM260420	c.3154C>T	p.R1052*	Substitution - Nonsense	Thyroid
COSM127803	c.1740A>C	p.T580T	Substitution - coding silent	Thyroid
COSM4855522	c.2737G>A	p.E913K	Substitution - Missense	Cervix
COSM4853950	c.3101+2T>A	p.?	Unknown	Cervix
COSM2931086	c.5339C>T	p.P1780L	Substitution - Missense	Liver
COSM3724844	c.4372G>T	p.E1458*	Substitution - Nonsense	Lung
COSM1413023	c.2133delT	p.F711fs*22	Deletion - Frameshift	Large_intestine
COSM1713786	c.1702C>T	p.P568S	Substitution - Missense	Skin
COSM5793758	c.6388G>A	p.D2130N	Substitution - Missense	Breast
COSM4100179	c.4866C>T	p.G1622G	Substitution - coding silent	Stomach
COSM4603233	c.4878_4879insC	p.A1627fs*53	Insertion - Frameshift	Upper_aerodigestive_tract
COSM1028977	c.3980C>A	p.S1327*	Substitution - Nonsense	Endometrium
COSM1028982	c.2969A>G	p.H990R	Substitution - Missense	Endometrium
COSM444191	c.697G>A	p.D233N	Substitution - Missense	Breast
COSM4100225	c.246G>A	p.R82R	Substitution - coding silent	Stomach
COSM1028979	c.3541+6C>T	p.?	Unknown	Endometrium
COSM3548786	c.4148G>A	p.R1383K	Substitution - Missense	Skin
COSM4677521	c.859C>T	p.R287C	Substitution - Missense	Large_intestine
COSM5554470	c.3432C>T	p.G1144G	Substitution - coding silent	Prostate
COSM4491038	c.3733C>T	p.P1245S	Substitution - Missense	Skin
COSM2931100	c.5018C>T	p.P1673L	Substitution - Missense	Large_intestine
COSM3389887	c.6486G>A	p.E2162E	Substitution - coding silent	Pancreas
COSM1130582	c.2892C>T	p.S964S	Substitution - coding silent	Prostate
COSM4484713	c.2842C>T	p.P948S	Substitution - Missense	Skin
COSM4100183	c.4449C>T	p.N1483N	Substitution - coding silent	Stomach
COSM2152146	c.253G>A	p.G85S	Substitution - Missense	Central_nervous_system
COSM1307605	c.5471G>C	p.R1824T	Substitution - Missense	Urinary_tract
COSM5639026	c.4428G>C	p.Q1476H	Substitution - Missense	Oesophagus
COSM3379108	c.6489C>T	p.A2163A	Substitution - coding silent	Pancreas
COSM4603233	c.4878_4879insC	p.A1627fs*53	Insertion - Frameshift	Upper_aerodigestive_tract
COSM280384	c.4310C>T	p.A1437V	Substitution - Missense	Large_intestine
COSM3548792	c.3779C>T	p.S1260L	Substitution - Missense	Skin
COSM1190306	c.5548G>T	p.G1850W	Substitution - Missense	Lung
COSM4898760	c.6338G>A	p.R2113K	Substitution - Missense	Skin
COSM4134751	c.4691G>T	p.R1564M	Substitution - Missense	Thyroid
COSM258883	c.5648G>T	p.G1883V	Substitution - Missense	Large_intestine
COSM1681831	c.3986A>T	p.D1329V	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3548770	c.6020C>T	p.S2007L	Substitution - Missense	Prostate
COSM3548788	c.4024C>T	p.L1342F	Substitution - Missense	Skin
COSM3799744	c.4324G>C	p.D1442H	Substitution - Missense	Urinary_tract
COSM4611940	c.1712_1713delCT	p.S571fs*4	Deletion - Frameshift	Large_intestine
COSM1307616	c.901G>A	p.E301K	Substitution - Missense	Urinary_tract
COSM280385	c.3530T>G	p.F1177C	Substitution - Missense	Large_intestine
COSM4293948	c.4924A>C	p.T1642P	Substitution - Missense	Upper_aerodigestive_tract
COSM4850274	c.4996G>A	p.G1666S	Substitution - Missense	Cervix
COSM2931133	c.3738C>T	p.L1246L	Substitution - coding silent	Large_intestine
COSM1413011	c.5652C>T	p.G1884G	Substitution - coding silent	Large_intestine
COSM1723061	c.4927_4928insC	p.R1643fs*37	Insertion - Frameshift	Large_intestine
COSM3799745	c.3192G>C	p.Q1064H	Substitution - Missense	Urinary_tract
COSM139202	c.332C>T	p.S111F	Substitution - Missense	Skin
COSM1028983	c.2688G>A	p.P896P	Substitution - coding silent	Endometrium
COSM3548807	c.1610C>T	p.S537F	Substitution - Missense	Skin
COSM459704	c.2332-8C>T	p.?	Unknown	Skin
COSM1413028	c.1425delA	p.E476fs*4	Deletion - Frameshift	Large_intestine
COSM109496	c.3989C>T	p.P1330L	Substitution - Missense	Skin
COSM1190305	c.5549G>C	p.G1850A	Substitution - Missense	Lung
COSM1028966	c.5768T>G	p.F1923C	Substitution - Missense	Endometrium
COSM4603233	c.4878_4879insC	p.A1627fs*53	Insertion - Frameshift	Upper_aerodigestive_tract
COSM1615832	c.3116G>T	p.R1039L	Substitution - Missense	Liver
COSM3911763	c.638T>C	p.L213P	Substitution - Missense	Skin
COSM1307614	c.1511C>T	p.S504L	Substitution - Missense	Urinary_tract
COSM1028992	c.1622C>T	p.A541V	Substitution - Missense	Endometrium
COSM1413018	c.3627C>T	p.D1209D	Substitution - coding silent	Large_intestine
COSM5645211	c.3420C>T	p.F1140F	Substitution - coding silent	Oesophagus
COSM1250082	c.6376G>A	p.E2126K	Substitution - Missense	Oesophagus
COSM2931286	c.893G>A	p.G298D	Substitution - Missense	Large_intestine
COSM4677516	c.1815G>A	p.S605S	Substitution - coding silent	Large_intestine
COSM1172739	c.374C>A	p.P125H	Substitution - Missense	Oesophagus
COSM4565946	c.275_276CC>TT	p.S92F	Substitution - Missense	Skin
COSM3548784	c.4451A>C	p.K1484T	Substitution - Missense	Skin
COSM3389890	c.1784C>G	p.P595R	Substitution - Missense	Pancreas
COSM1028996	c.1217C>T	p.A406V	Substitution - Missense	Endometrium
COSM1136807	c.5423C>T	p.P1808L	Substitution - Missense	Kidney
COSM1723061	c.4927_4928insC	p.R1643fs*37	Insertion - Frameshift	Large_intestine
COSM127803	c.1740A>C	p.T580T	Substitution - coding silent	Thyroid
COSM291549	c.2938G>A	p.A980T	Substitution - Missense	Large_intestine
COSM724829	c.2713G>A	p.E905K	Substitution - Missense	Lung
COSM4958552	c.1478G>A	p.G493E	Substitution - Missense	Liver
COSM3693629	c.6184G>A	p.D2062N	Substitution - Missense	Large_intestine
COSM4134763	c.102C>T	p.I34I	Substitution - coding silent	Thyroid
COSM4677497	c.6249C>T	p.F2083F	Substitution - coding silent	Large_intestine
COSM1307611	c.3776G>T	p.G1259V	Substitution - Missense	Urinary_tract
COSM5750138	c.2360A>G	p.N787S	Substitution - Missense	Stomach
COSM3758729	c.4702A>G	p.T1568A	Substitution - Missense	Thyroid
COSM1681834	c.1834A>G	p.R612G	Substitution - Missense	Large_intestine
COSM244037	c.1105A>G	p.R369G	Substitution - Missense	Prostate
COSM4640292	c.5056C>T	p.P1686S	Substitution - Missense	Large_intestine
COSM5930010	c.6143C>T	p.S2048F	Substitution - Missense	Skin
COSM2931348	c.210C>T	p.R70R	Substitution - coding silent	Large_intestine
COSM377224	c.4441G>T	p.E1481*	Substitution - Nonsense	Lung
COSM4484313	c.2797C>T	p.P933S	Substitution - Missense	Skin
COSM342371	c.2511G>C	p.L837F	Substitution - Missense	Breast
COSM1757015	c.4470G>C	p.K1490N	Substitution - Missense	Urinary_tract
COSM4921936	c.4404G>T	p.A1468A	Substitution - coding silent	Liver
COSM402221	c.1839G>T	p.Q613H	Substitution - Missense	Lung
COSM2931214	c.1545G>T	p.K515N	Substitution - Missense	Large_intestine
COSM3799747	c.2133T>A	p.F711L	Substitution - Missense	Urinary_tract
COSM4581968	c.11A>T	p.K4I	Substitution - Missense	Bone
COSM724824	c.1791G>A	p.R597R	Substitution - coding silent	Lung
COSM5552625	c.2773G>A	p.D925N	Substitution - Missense	Prostate
COSM4677512	c.2407G>T	p.E803*	Substitution - Nonsense	Large_intestine
COSM4591407	c.4872G>C	p.K1624N	Substitution - Missense	Upper_aerodigestive_tract
COSM3841473	c.784G>A	p.E262K	Substitution - Missense	Breast
COSM224062	c.3119C>T	p.S1040F	Substitution - Missense	Skin
COSM3758729	c.4702A>G	p.T1568A	Substitution - Missense	Large_intestine
COSM1028999	c.542T>G	p.L181R	Substitution - Missense	Endometrium
COSM1203594	c.6619C>T	p.R2207W	Substitution - Missense	Large_intestine
COSM1327504	c.400G>C	p.E134Q	Substitution - Missense	Ovary
COSM3693703	c.1224C>T	p.P408P	Substitution - coding silent	Large_intestine
COSM5028728	c.3307T>A	p.W1103R	Substitution - Missense	Breast
COSM1681834	c.1834A>G	p.R612G	Substitution - Missense	Large_intestine
COSM4603233	c.4878_4879insC	p.A1627fs*53	Insertion - Frameshift	Upper_aerodigestive_tract
COSM5686112	c.2911G>T	p.A971S	Substitution - Missense	Soft_tissue
COSM1566161	c.4057G>A	p.G1353R	Substitution - Missense	Large_intestine
COSM3770872	c.5597C>T	p.A1866V	Substitution - Missense	Pancreas
COSM724823	c.1465A>G	p.S489G	Substitution - Missense	Lung
COSM1028985	c.2319G>C	p.R773S	Substitution - Missense	Endometrium
COSM1028972	c.4333C>T	p.P1445S	Substitution - Missense	Endometrium
COSM4501454	c.5891C>T	p.P1964L	Substitution - Missense	Skin
COSM4186981	c.2306C>T	p.T769M	Substitution - Missense	Kidney
COSM4100217	c.622A>G	p.T208A	Substitution - Missense	Stomach
COSM4677503	c.4693C>T	p.R1565C	Substitution - Missense	Large_intestine
COSM4677504	c.4515C>T	p.A1505A	Substitution - coding silent	Large_intestine
COSM5741938	c.6556A>T	p.R2186W	Substitution - Missense	Small_intestine
COSM1028981	c.3218C>T	p.A1073V	Substitution - Missense	Endometrium
COSM3389886	c.6547C>T	p.R2183*	Substitution - Nonsense	Pancreas
COSM1413034	c.686C>T	p.A229V	Substitution - Missense	Large_intestine
COSM4677510	c.2607G>A	p.P869P	Substitution - coding silent	Large_intestine
COSM5569434	c.6244A>T	p.T2082S	Substitution - Missense	Prostate
COSM1307604	c.5893C>T	p.Q1965*	Substitution - Nonsense	Urinary_tract
COSM4603233	c.4878_4879insC	p.A1627fs*53	Insertion - Frameshift	Upper_aerodigestive_tract
COSM127803	c.1740A>C	p.T580T	Substitution - coding silent	Upper_aerodigestive_tract
COSM345162	c.5893C>G	p.Q1965E	Substitution - Missense	Lung
COSM74378	c.1246G>A	p.D416N	Substitution - Missense	Ovary
COSM1713784	c.3082C>T	p.P1028S	Substitution - Missense	Skin
COSM1028964	c.6248_6249insT	p.E2084fs*9	Insertion - Frameshift	Endometrium
COSM3841469	c.1389C>A	p.I463I	Substitution - coding silent	Breast
COSM4855263	c.4253C>A	p.A1418E	Substitution - Missense	Cervix
COSM1028986	c.2176C>T	p.R726C	Substitution - Missense	Endometrium
COSM4100176	c.6326C>T	p.A2109V	Substitution - Missense	Prostate
COSM4756275	c.1046A>T	p.D349V	Substitution - Missense	Stomach
COSM5567692	c.6462C>T	p.S2154S	Substitution - coding silent	Prostate
COSM252474	c.1358C>T	p.P453L	Substitution - Missense	Ovary
COSM3707918	c.3204A>G	p.K1068K	Substitution - coding silent	Liver
COSM1413022	c.2227C>T	p.R743C	Substitution - Missense	Skin
COSM339410	c.5054G>T	p.C1685F	Substitution - Missense	Lung
COSM1028988	c.2011C>T	p.R671W	Substitution - Missense	Endometrium
COSM3770874	c.3496G>A	p.A1166T	Substitution - Missense	Pancreas
COSM5819862	c.4881G>T	p.A1627A	Substitution - coding silent	Liver
COSM4488952	c.3404C>T	p.S1135F	Substitution - Missense	Skin
COSM4634557	c.1008G>T	p.Q336H	Substitution - Missense	Large_intestine
COSM4603233	c.4878_4879insC	p.A1627fs*53	Insertion - Frameshift	Upper_aerodigestive_tract
COSM5556962	c.5356A>G	p.I1786V	Substitution - Missense	Prostate
COSM4950262	c.2612_2613insA	p.Q872fs*8	Insertion - Frameshift	Liver
COSM5392551	c.2465C>T	p.P822L	Substitution - Missense	Skin
COSM4603233	c.4878_4879insC	p.A1627fs*53	Insertion - Frameshift	Upper_aerodigestive_tract
COSM1413012	c.5379A>G	p.R1793R	Substitution - coding silent	Large_intestine
COSM216496	c.2647T>C	p.L883L	Substitution - coding silent	Pancreas
COSM1238675	c.4771C>T	p.P1591S	Substitution - Missense	Oesophagus
COSM3548768	c.6380G>A	p.R2127Q	Substitution - Missense	Skin
COSM4603233	c.4878_4879insC	p.A1627fs*53	Insertion - Frameshift	Upper_aerodigestive_tract
COSM4591406	c.4867G>A	p.E1623K	Substitution - Missense	Upper_aerodigestive_tract
COSM1413030	c.1366G>A	p.G456S	Substitution - Missense	Large_intestine
COSM4383131	c.2650A>T	p.K884*	Substitution - Nonsense	Large_intestine
COSM1413019	c.3332C>T	p.S1111F	Substitution - Missense	Large_intestine
COSM1723061	c.4927_4928insC	p.R1643fs*37	Insertion - Frameshift	Large_intestine
COSM5914282	c.5792C>T	p.P1931L	Substitution - Missense	Skin
COSM5892434	c.6074C>T	p.P2025L	Substitution - Missense	Skin
COSM4624313	c.3751G>A	p.A1251T	Substitution - Missense	Large_intestine
COSM118758	c.4056C>T	p.D1352D	Substitution - coding silent	Ovary
COSM4443425	c.3373G>A	p.A1125T	Substitution - Missense	Large_intestine
COSM4100181	c.4551G>T	p.S1517S	Substitution - coding silent	Stomach
COSM1751550	c.1863A>G	p.A621A	Substitution - coding silent	Urinary_tract
COSM5941007	c.1783C>T	p.P595S	Substitution - Missense	Skin
COSM160425	c.5409G>T	p.Q1803H	Substitution - Missense	Breast
COSM2931107	c.4711G>A	p.G1571S	Substitution - Missense	Large_intestine
COSM1028991	c.1802C>T	p.S601F	Substitution - Missense	Endometrium
COSM3548817	c.558T>C	p.S186S	Substitution - coding silent	Skin
COSM1713783	c.3488C>T	p.P1163L	Substitution - Missense	Skin
COSM1743166	c.5161G>C	p.G1721R	Substitution - Missense	Biliary_tract
COSM2931110	c.4544C>T	p.S1515L	Substitution - Missense	Oesophagus
COSM4624315	c.175C>T	p.L59L	Substitution - coding silent	Large_intestine
COSM4603233	c.4878_4879insC	p.A1627fs*53	Insertion - Frameshift	Upper_aerodigestive_tract
COSM4100221	c.457G>A	p.D153N	Substitution - Missense	Stomach
COSM3911767	c.590C>T	p.P197L	Substitution - Missense	Skin
COSM1028988	c.2011C>T	p.R671W	Substitution - Missense	Large_intestine
COSM4137120	c.5301C>T	p.H1767H	Substitution - coding silent	Ovary
COSM4603233	c.4878_4879insC	p.A1627fs*53	Insertion - Frameshift	Upper_aerodigestive_tract
COSM213213	c.3330G>C	p.K1110N	Substitution - Missense	Breast
COSM4423934	c.6121T>C	p.W2041R	Substitution - Missense	Prostate
COSM4611936	c.1715_1717delCTT	p.S572delS	Deletion - In frame	Large_intestine
COSM5057490	c.2679C>T	p.D893D	Substitution - coding silent	Stomach
COSM5028727	c.4500C>G	p.L1500L	Substitution - coding silent	Breast
COSM244038	c.2417C>T	p.P806L	Substitution - Missense	Prostate
COSM5934003	c.5246C>T	p.P1749L	Substitution - Missense	Skin
COSM1327506	c.5199C>T	p.T1733T	Substitution - coding silent	Ovary
COSM444187	c.4572A>C	p.P1524P	Substitution - coding silent	Breast
COSM107386	c.3988C>T	p.P1330S	Substitution - Missense	Skin
COSM2931179	c.2236C>T	p.R746C	Substitution - Missense	Stomach
COSM4100186	c.4325A>T	p.D1442V	Substitution - Missense	Stomach
COSM724822	c.1086A>C	p.E362D	Substitution - Missense	Lung
COSM5085404	c.5985C>T	p.S1995S	Substitution - coding silent	Prostate
COSM3911760	c.4089C>T	p.I1363I	Substitution - coding silent	Skin
COSM5494120	c.4394C>T	p.A1465V	Substitution - Missense	Biliary_tract
COSM4603233	c.4878_4879insC	p.A1627fs*53	Insertion - Frameshift	Upper_aerodigestive_tract
COSM1190310	c.1094G>T	p.G365V	Substitution - Missense	Lung
COSM2931351	c.129G>A	p.A43A	Substitution - coding silent	Breast
COSM3423807	c.3914C>T	p.S1305L	Substitution - Missense	Skin
COSM3423807	c.3914C>T	p.S1305L	Substitution - Missense	Large_intestine
COSM3548791	c.3791C>T	p.P1264L	Substitution - Missense	Skin
COSM1413020	c.2507T>C	p.M836T	Substitution - Missense	Large_intestine
COSM1307608	c.4509G>A	p.Q1503Q	Substitution - coding silent	Urinary_tract
COSM1028971	c.4493A>G	p.E1498G	Substitution - Missense	Endometrium
COSM4100176	c.6326C>T	p.A2109V	Substitution - Missense	Stomach
COSM444192	c.483G>A	p.L161L	Substitution - coding silent	Breast
COSM4401765	c.1570C>T	p.P524S	Substitution - Missense	Skin
COSM403772	c.4732C>T	p.L1578F	Substitution - Missense	Lung
COSM4591407	c.4872G>C	p.K1624N	Substitution - Missense	Upper_aerodigestive_tract
COSM4134752	c.2669C>G	p.S890C	Substitution - Missense	Thyroid
COSM5741939	c.4175A>G	p.D1392G	Substitution - Missense	Small_intestine
COSM403773	c.4605C>G	p.F1535L	Substitution - Missense	Lung
COSM2152146	c.253G>A	p.G85S	Substitution - Missense	Central_nervous_system
COSM1028974	c.4216C>T	p.R1406W	Substitution - Missense	Large_intestine
COSM4591406	c.4867G>A	p.E1623K	Substitution - Missense	Upper_aerodigestive_tract
COSM4100184	c.4430A>C	p.K1477T	Substitution - Missense	Stomach
COSM1238674	c.1698C>T	p.L566L	Substitution - coding silent	Oesophagus
COSM5392547	c.4296C>T	p.T1432T	Substitution - coding silent	Skin
COSM1028986	c.2176C>T	p.R726C	Substitution - Missense	Skin
COSM2931295	c.657C>T	p.P219P	Substitution - coding silent	Skin
COSM2931186	c.1889G>A	p.G630D	Substitution - Missense	Stomach
COSM280387	c.1412C>A	p.A471D	Substitution - Missense	Large_intestine
COSM4591407	c.4872G>C	p.K1624N	Substitution - Missense	Upper_aerodigestive_tract
COSM4624313	c.3751G>A	p.A1251T	Substitution - Missense	Large_intestine
COSM1028987	c.2157T>G	p.N719K	Substitution - Missense	Endometrium
COSM4677505	c.4407G>A	p.T1469T	Substitution - coding silent	Large_intestine
COSM5547503	c.1200delC	p.C402fs*25	Deletion - Frameshift	Prostate
COSM1483833	c.77C>T	p.T26I	Substitution - Missense	Breast
COSM3911761	c.2723C>T	p.P908L	Substitution - Missense	Skin
COSM4624313	c.3751G>A	p.A1251T	Substitution - Missense	Large_intestine
COSM4449726	c.3131delG	p.G1044fs*76	Deletion - Frameshift	Skin
COSM4100187	c.4217G>A	p.R1406Q	Substitution - Missense	Stomach
COSM4877641	c.3637G>A	p.E1213K	Substitution - Missense	Prostate
COSM1029002	c.25A>G	p.N9D	Substitution - Missense	Endometrium
COSM225800	c.1658C>T	p.P553L	Substitution - Missense	Skin
COSM5451588	c.4211G>A	p.R1404Q	Substitution - Missense	Large_intestine
COSM1028981	c.3218C>T	p.A1073V	Substitution - Missense	Large_intestine
COSM4677507	c.3797delC	p.P1266fs*8	Deletion - Frameshift	Large_intestine
COSM4677507	c.3797delC	p.P1266fs*8	Deletion - Frameshift	Large_intestine
COSM4557218	c.719G>A	p.G240E	Substitution - Missense	Skin
COSM1028975	c.4110C>A	p.F1370L	Substitution - Missense	Endometrium
COSM373068	c.1148A>C	p.K383T	Substitution - Missense	Lung
COSM5648768	c.1759C>T	p.P587S	Substitution - Missense	Oesophagus
COSM4677525	c.732G>A	p.Q244Q	Substitution - coding silent	Large_intestine
COSM379271	c.188G>A	p.R63H	Substitution - Missense	Lung
COSM3758729	c.4702A>G	p.T1568A	Substitution - Missense	Large_intestine
COSM2931063	c.6176C>T	p.P2059L	Substitution - Missense	Skin
COSM1649942	c.4225G>A	p.E1409K	Substitution - Missense	Urinary_tract
COSM5767176	c.2493C>T	p.D831D	Substitution - coding silent	Breast
COSM160428	c.4258G>A	p.E1420K	Substitution - Missense	Stomach
COSM4440603	c.6101delC	p.P2034fs*>207	Deletion - Frameshift	Thyroid
COSM4440603	c.6101delC	p.P2034fs*>207	Deletion - Frameshift	Large_intestine
COSM4100229	c.219C>T	p.R73R	Substitution - coding silent	Stomach
COSM3548825	c.88C>T	p.R30*	Substitution - Nonsense	Skin
COSM160424	c.5239C>G	p.Q1747E	Substitution - Missense	Breast
COSM1413009	c.6051G>T	p.Q2017H	Substitution - Missense	Large_intestine
COSM1615833	c.2536G>T	p.A846S	Substitution - Missense	Stomach
COSM1751551	c.1738A>C	p.T580P	Substitution - Missense	Urinary_tract
COSM384940	c.4485G>T	p.E1495D	Substitution - Missense	Lung
COSM4677498	c.5998G>A	p.E2000K	Substitution - Missense	Large_intestine
COSM3841477	c.403C>T	p.R135*	Substitution - Nonsense	Breast
COSM4293948	c.4924A>C	p.T1642P	Substitution - Missense	Upper_aerodigestive_tract
COSM1413010	c.5812C>T	p.R1938W	Substitution - Missense	Large_intestine
COSM4293948	c.4924A>C	p.T1642P	Substitution - Missense	Upper_aerodigestive_tract
COSM4591406	c.4867G>A	p.E1623K	Substitution - Missense	Upper_aerodigestive_tract
COSM1203596	c.110G>A	p.R37Q	Substitution - Missense	Large_intestine
COSM4624313	c.3751G>A	p.A1251T	Substitution - Missense	Large_intestine
COSM216496	c.2647T>C	p.L883L	Substitution - coding silent	Pancreas
COSM3731467	c.3102-1G>T	p.?	Unknown	Stomach
COSM5889395	c.3185A>C	p.N1062T	Substitution - Missense	Skin
COSM252474	c.1358C>T	p.P453L	Substitution - Missense	Skin
COSM1203598	c.4172A>G	p.Y1391C	Substitution - Missense	Large_intestine
COSM4921898	c.5596G>A	p.A1866T	Substitution - Missense	Liver
COSM3721478	c.5574C>T	p.A1858A	Substitution - coding silent	Upper_aerodigestive_tract
COSM5432350	c.3669G>A	p.A1223A	Substitution - coding silent	Oesophagus
COSM6017988	c.1090C>T	p.Q364*	Substitution - Nonsense	Skin
COSM4966344	c.1174C>T	p.P392S	Substitution - Missense	Prostate
COSM5442691	c.4107G>C	p.Q1369H	Substitution - Missense	Oesophagus
COSM1566159	c.3595delA	p.I1199fs*10	Deletion - Frameshift	Large_intestine
COSM3548775	c.5402G>A	p.G1801E	Substitution - Missense	Skin
COSM724835	c.4412C>T	p.S1471F	Substitution - Missense	Lung
COSM4924497	c.3425G>A	p.S1142N	Substitution - Missense	Liver
COSM143550	c.5413_5414GG>AA	p.G1805K	Substitution - Missense	Skin
COSM4100195	c.2534G>A	p.R845H	Substitution - Missense	Stomach
COSM4677505	c.4407G>A	p.T1469T	Substitution - coding silent	Large_intestine
COSM4100191	c.2893G>T	p.G965C	Substitution - Missense	Stomach
COSM127803	c.1740A>C	p.T580T	Substitution - coding silent	Thyroid
COSM5451588	c.4211G>A	p.R1404Q	Substitution - Missense	Biliary_tract
COSM1413005	c.6451C>T	p.R2151W	Substitution - Missense	Large_intestine
COSM4844710	c.2362G>A	p.E788K	Substitution - Missense	Cervix
COSM5474297	c.6177C>T	p.P2059P	Substitution - coding silent	Large_intestine
COSM4677497	c.6249C>T	p.F2083F	Substitution - coding silent	Large_intestine
COSM5519754	c.2237G>A	p.R746H	Substitution - Missense	Biliary_tract
COSM269013	c.633C>T	p.G211G	Substitution - coding silent	Large_intestine
COSM4958552	c.1478G>A	p.G493E	Substitution - Missense	Liver
COSM395888	c.5872G>T	p.G1958C	Substitution - Missense	Lung
COSM5436962	c.1625C>A	p.A542E	Substitution - Missense	Oesophagus
COSM4550247	c.4968G>A	p.R1656R	Substitution - coding silent	Skin
COSM1757016	c.3809C>T	p.P1270L	Substitution - Missense	Urinary_tract
COSM3363362	c.2301T>C	p.L767L	Substitution - coding silent	Kidney
COSM1203595	c.5533C>T	p.R1845C	Substitution - Missense	Large_intestine
COSM1028995	c.1271C>T	p.A424V	Substitution - Missense	Endometrium
COSM4891264	c.6297G>T	p.P2099P	Substitution - coding silent	Upper_aerodigestive_tract
COSM4913154	c.5487T>C	p.S1829S	Substitution - coding silent	Liver
COSM5894078	c.4072C>T	p.P1358S	Substitution - Missense	Skin
COSM724841	c.5299C>T	p.H1767Y	Substitution - Missense	Lung
COSM2931068	c.6088C>T	p.P2030S	Substitution - Missense	Skin
COSM4677529	c.575G>A	p.R192H	Substitution - Missense	Large_intestine
COSM4100189	c.3911C>T	p.A1304V	Substitution - Missense	Stomach
COSM4639470	c.6523C>A	p.R2175R	Substitution - coding silent	Large_intestine
COSM4603233	c.4878_4879insC	p.A1627fs*53	Insertion - Frameshift	Upper_aerodigestive_tract
COSM4603233	c.4878_4879insC	p.A1627fs*53	Insertion - Frameshift	Upper_aerodigestive_tract
COSM2931339	c.248G>A	p.R83H	Substitution - Missense	Stomach
COSM724827	c.2553C>T	p.L851L	Substitution - coding silent	Lung
COSM4624314	c.3689A>C	p.K1230T	Substitution - Missense	Large_intestine
COSM5776402	c.5962C>A	p.Q1988K	Substitution - Missense	Breast
COSM5777339	c.2332G>C	p.V778L	Substitution - Missense	Breast
COSM5444257	c.345G>A	p.V115V	Substitution - coding silent	Oesophagus
COSM3548802	c.1770C>T	p.F590F	Substitution - coding silent	Skin
COSM5776430	c.1880A>T	p.K627M	Substitution - Missense	Breast
COSM119642	c.6175C>G	p.P2059A	Substitution - Missense	Ovary
COSM5444039	c.1326G>C	p.K442N	Substitution - Missense	Oesophagus
COSM4423933	c.6122G>T	p.W2041L	Substitution - Missense	Prostate
COSM4478266	c.2224C>T	p.H742Y	Substitution - Missense	Skin
COSM5974153	c.3375C>A	p.A1125A	Substitution - coding silent	Upper_aerodigestive_tract
COSM3548821	c.440A>G	p.D147G	Substitution - Missense	Skin
COSM5440266	c.2063A>C	p.D688A	Substitution - Missense	Oesophagus
COSM216496	c.2647T>C	p.L883L	Substitution - coding silent	Pancreas
COSM3548771	c.5996C>T	p.S1999F	Substitution - Missense	Skin
COSM5807969	c.334G>T	p.E112*	Substitution - Nonsense	Liver
COSM5365808	c.6497delG	p.G2166fs*>75	Deletion - Frameshift	Large_intestine
COSM2931315	c.418G>C	p.E140Q	Substitution - Missense	Upper_aerodigestive_tract
COSM4551900	c.543G>A	p.L181L	Substitution - coding silent	Skin
COSM1028989	c.1992G>A	p.S664S	Substitution - coding silent	Endometrium
COSM4977894	c.2316G>C	p.E772D	Substitution - Missense	Oesophagus
COSM5613010	c.4086G>T	p.P1362P	Substitution - coding silent	Adrenal_gland
COSM4411501	c.5523A>G	p.Q1841Q	Substitution - coding silent	Oesophagus
COSM4496896	c.4854C>T	p.P1618P	Substitution - coding silent	Skin
COSM5392549	c.3905C>T	p.S1302F	Substitution - Missense	Skin
COSM1284496	c.5200G>T	p.A1734S	Substitution - Missense	Autonomic_ganglia
COSM3423806	c.5440C>T	p.Q1814*	Substitution - Nonsense	Large_intestine
COSM4800152	c.2959G>C	p.D987H	Substitution - Missense	Liver
COSM5583436	c.1527C>A	p.H509Q	Substitution - Missense	Skin
COSM5637511	c.6590G>A	p.R2197Q	Substitution - Missense	Oesophagus
COSM444188	c.4516G>A	p.A1506T	Substitution - Missense	Breast
COSM4019734	c.4548G>T	p.V1516V	Substitution - coding silent	Oesophagus
COSM1713781	c.4220G>A	p.R1407H	Substitution - Missense	Skin
COSM724839	c.4707G>A	p.E1569E	Substitution - coding silent	Lung
COSM3548770	c.6020C>T	p.S2007L	Substitution - Missense	Skin
COSM1028974	c.4216C>T	p.R1406W	Substitution - Missense	Endometrium
COSM3548809	c.1525C>T	p.H509Y	Substitution - Missense	Skin
COSM115803	c.5435C>T	p.S1812L	Substitution - Missense	Ovary
COSM4401384	c.2581C>T	p.P861S	Substitution - Missense	Skin
COSM3933907	c.4351G>C	p.D1451H	Substitution - Missense	Urinary_tract
COSM4677496	c.6317A>G	p.Q2106R	Substitution - Missense	Large_intestine
COSM1615837	c.128C>T	p.A43V	Substitution - Missense	Liver
COSM4677500	c.5058G>A	p.P1686P	Substitution - coding silent	Large_intestine
COSM287709	c.453C>T	p.T151T	Substitution - coding silent	Large_intestine
COSM1028963	c.6579G>A	p.R2193R	Substitution - coding silent	Endometrium
COSM3423807	c.3914C>T	p.S1305L	Substitution - Missense	Stomach
COSM4100177	c.6296C>A	p.P2099Q	Substitution - Missense	Stomach
COSM1718608	c.6046C>T	p.P2016S	Substitution - Missense	Skin
COSM4100193	c.2540A>G	p.H847R	Substitution - Missense	Stomach
COSM5921679	c.3413C>T	p.S1138F	Substitution - Missense	Skin
COSM1028976	c.4101C>T	p.F1367F	Substitution - coding silent	Endometrium
COSM1723061	c.4927_4928insC	p.R1643fs*37	Insertion - Frameshift	Large_intestine
COSM724832	c.3534G>T	p.E1178D	Substitution - Missense	Lung
COSM4100199	c.1804G>A	p.A602T	Substitution - Missense	Stomach
COSM4502369	c.6118C>T	p.R2040C	Substitution - Missense	Skin
COSM2931126	c.3999A>G	p.R1333R	Substitution - coding silent	Oesophagus
COSM3548793	c.3165C>T	p.T1055T	Substitution - coding silent	Skin
COSM149207	c.1666G>A	p.A556T	Substitution - Missense	Large_intestine
COSM4677502	c.4897G>A	p.G1633S	Substitution - Missense	Large_intestine
COSM5458847	c.5065G>A	p.A1689T	Substitution - Missense	Large_intestine
COSM5899330	c.4159C>T	p.P1387S	Substitution - Missense	Skin
COSM2931064	c.6161C>T	p.A2054V	Substitution - Missense	Stomach
COSM3548774	c.5544C>T	p.P1848P	Substitution - coding silent	Skin
COSM5017382	c.4928_4929insC	p.A1645fs*35	Insertion - Frameshift	Soft_tissue
COSM1307613	c.2239G>C	p.E747Q	Substitution - Missense	Urinary_tract
COSM3548770	c.6020C>T	p.S2007L	Substitution - Missense	Prostate
COSM3673160	c.3707A>G	p.Q1236R	Substitution - Missense	Prostate
COSM4591407	c.4872G>C	p.K1624N	Substitution - Missense	Upper_aerodigestive_tract
COSM127803	c.1740A>C	p.T580T	Substitution - coding silent	Thyroid
COSM6017986	c.2657A>T	p.K886M	Substitution - Missense	Skin
COSM3548779	c.5032G>A	p.G1678S	Substitution - Missense	Skin
COSM1615832	c.3116G>T	p.R1039L	Substitution - Missense	Liver
COSM1718608	c.6046C>T	p.P2016S	Substitution - Missense	Skin
COSM4677506	c.4126C>G	p.L1376V	Substitution - Missense	Large_intestine
COSM4883561	c.774G>T	p.K258N	Substitution - Missense	Upper_aerodigestive_tract
COSM1641413	c.6006_6007insA	p.E2003fs*90	Insertion - Frameshift	Stomach
COSM4500388	c.5649C>T	p.G1883G	Substitution - coding silent	Skin
COSM5456836	c.3711G>A	p.S1237S	Substitution - coding silent	Large_intestine
COSM1028970	c.5139C>T	p.S1713S	Substitution - coding silent	Endometrium
COSM3389892	c.444C>T	p.H148H	Substitution - coding silent	Pancreas
COSM1028993	c.1568C>T	p.S523L	Substitution - Missense	Endometrium
COSM5392555	c.1137G>A	p.K379K	Substitution - coding silent	Skin
COSM1028984	c.2480C>T	p.A827V	Substitution - Missense	Endometrium
COSM6017982	c.3239T>A	p.F1080Y	Substitution - Missense	Skin
COSM4293948	c.4924A>C	p.T1642P	Substitution - Missense	Upper_aerodigestive_tract
COSM1413026	c.1738A>T	p.T580S	Substitution - Missense	Large_intestine
COSM4603233	c.4878_4879insC	p.A1627fs*53	Insertion - Frameshift	Upper_aerodigestive_tract
COSM4497695	c.502C>T	p.L168F	Substitution - Missense	Skin
COSM5366096	c.2235G>A	p.L745L	Substitution - coding silent	Large_intestine
COSM4498959	c.5313C>T	p.F1771F	Substitution - coding silent	Skin
COSM1028968	c.5400C>T	p.F1800F	Substitution - coding silent	Endometrium
COSM4787512	c.2006A>G	p.Q669R	Substitution - Missense	Liver
COSM1735038	c.4406C>T	p.T1469M	Substitution - Missense	Pancreas
COSM1413016	c.3938C>T	p.P1313L	Substitution - Missense	Large_intestine
COSM4629415	c.2481G>A	p.A827A	Substitution - coding silent	Large_intestine
COSM2931235	c.1290C>T	p.S430S	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM4982519	c.4509G>C	p.Q1503H	Substitution - Missense	Oesophagus
COSM4100178	c.5247G>A	p.P1749P	Substitution - coding silent	Stomach
COSM4100188	c.4180G>A	p.E1394K	Substitution - Missense	Stomach
COSM724828	c.2630C>T	p.S877F	Substitution - Missense	Lung
COSM3548789	c.3857C>T	p.P1286L	Substitution - Missense	Skin
COSM4581963	c.3718A>C	p.K1240Q	Substitution - Missense	Bone
COSM2931339	c.248G>A	p.R83H	Substitution - Missense	Large_intestine
COSM4541323	c.2984G>C	p.R995T	Substitution - Missense	Skin
COSM294310	c.1172C>T	p.A391V	Substitution - Missense	Large_intestine
COSM3548782	c.4847C>T	p.S1616F	Substitution - Missense	Skin

> Text Mining based Variations

[ TOP ]

PMID	Variation	Cancer	Evidence
28099595	mutation	Kaposiform Hemangioendothelioma	The mutations in ITGB2, IL-32 and DIDO1 were included in them.

Summary
Symbol	DIDO1
Name	death inducer-obliterator 1
Aliases	dJ885L7.8; FLJ11265; KIAA0333; DIO-1; BYE1; C20orf158; DATF1; chromosome 20 open reading frame 158; death as ......
Location	20q13.33
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

[ TOP ]

Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant
Q9BTC0	60	S	Phosphoserine	-	No	None detected
Q9BTC0	114	S	Phosphoserine	-	No	None detected
Q9BTC0	151	T	Phosphothreonine	-	No	None detected
Q9BTC0	152	S	Phosphoserine	-	No	None detected
Q9BTC0	154	S	Phosphoserine	-	No	None detected
Q9BTC0	523	S	Phosphoserine	-	Yes	p.S523L (cancer: UCEC)
Q9BTC0	805	S	Phosphoserine	-	No	None detected
Q9BTC0	809	S	Phosphoserine	-	No	None detected
Q9BTC0	889	S	Phosphoserine	-	No	None detected
Q9BTC0	898	S	Phosphoserine	-	No	None detected
Q9BTC0	1019	S	Phosphoserine	-	Yes	p.S1019F (cancer: PAAD)
Q9BTC0	1030	S	Phosphoserine	-	No	None detected
Q9BTC0	1040	S	Phosphoserine	-	No	None detected
Q9BTC0	1244	Y	Phosphotyrosine	-	No	None detected
Q9BTC0	1256	T	Phosphothreonine	-	No	None detected
Q9BTC0	1260	S	Phosphoserine	-	Yes	p.S1260L (cancer: SKCM)
Q9BTC0	1312	S	Phosphoserine	-	No	None detected
Q9BTC0	1456	S	Phosphoserine	-	No	None detected
Q9BTC0	1469	T	Phosphothreonine	-	No	None detected
Q9BTC0	1522	S	Phosphoserine	-	No	None detected
Q9BTC0	1714	S	Phosphoserine	-	No	None detected
Q9BTC0	1835	R	Omega-N-methylarginine	-	No	None detected
Q9BTC0	1893	R	Asymmetric dimethylarginine	-	No	None detected
Q9BTC0	1894	R	Asymmetric dimethylarginine	-	No	None detected
Q9BTC0	1977	R	Asymmetric dimethylarginine	-	No	None detected
Q9BTC0	1982	R	Asymmetric dimethylarginine	-	No	None detected
Q9BTC0	1993	R	Asymmetric dimethylarginine	-	No	None detected
Q9BTC0	2008	R	Asymmetric dimethylarginine	-	No	None detected
Q9BTC0	2024	R	Asymmetric dimethylarginine	-	No	None detected

Summary
Symbol	DIDO1
Name	death inducer-obliterator 1
Aliases	dJ885L7.8; FLJ11265; KIAA0333; DIO-1; BYE1; C20orf158; DATF1; chromosome 20 open reading frame 158; death as ......
Location	20q13.33
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	6.383	6.256	-0.079	0.571	NS
BRCA	Breast invasive carcinoma	112	1100	6.579	6.641	0.109	0.0249	NS
CESC	Cervical and endocervical cancers	3	306	6.659	6.261	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	6.476	6.639	0.232	0.0211	NS
ESCA	Esophageal carcinoma	11	185	6.771	6.873	0.154	0.454	NS
GBM	Glioblastoma multiforme	5	166	6.067	6.047	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	6.139	6.018	-0.054	0.528	NS
KIRC	Kidney renal clear cell carcinoma	72	534	6.316	6.409	0.084	0.0371	NS
KIRP	Kidney renal papillary cell carcinoma	32	291	6.454	6.481	0.047	0.666	NS
LAML	Acute Myeloid Leukemia	0	173	NA	7.651	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	6.338	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	5.139	5.357	0.25	0.00135	NS
LUAD	Lung adenocarcinoma	59	517	6.371	6.313	0.014	0.855	NS
LUSC	Lung squamous cell carcinoma	51	501	6.24	6.218	-0.024	0.777	NS
OV	Ovarian serous cystadenocarcinoma	0	307	NA	6.791	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	6.199	6.392	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	5.851	6.228	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	6.494	6.475	0.006	0.922	NS
READ	Rectum adenocarcinoma	10	167	6.445	6.886	0.564	0.00497	NS
SARC	Sarcoma	2	263	6.044	6.173	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	6.232	6.509	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	6.762	6.888	0.233	0.014	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	6.928	NA	NA	NA
THCA	Thyroid carcinoma	59	509	6.677	6.382	-0.277	7.51e-12	NS
THYM	Thymoma	2	120	7.236	6.68	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	6.671	6.077	-0.553	6.36e-13	NS

> Cancer Cell Line Encyclopedia (CCLE)

[ TOP ]

Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	7.8
Autonomic ganglia	CHP212	7.4
Autonomic ganglia	IMR32	8
Autonomic ganglia	KELLY	7.5
Autonomic ganglia	KPNRTBM1	7.8
Autonomic ganglia	KPNSI9S	7.2
Autonomic ganglia	KPNYN	7.4
Autonomic ganglia	MHHNB11	7.4
Autonomic ganglia	NB1	7.4
Autonomic ganglia	NH6	7
Autonomic ganglia	SHSY5Y	7.8
Autonomic ganglia	SIMA	8.3
Autonomic ganglia	SKNAS	6.6
Autonomic ganglia	SKNBE2	7.6
Autonomic ganglia	SKNDZ	8
Autonomic ganglia	SKNFI	7.3
Autonomic ganglia	SKNSH	6.6
Biliary tract	HUCCT1	7.1
Biliary tract	HUH28	7.6
Biliary tract	SNU1079	7.2
Biliary tract	SNU1196	8.2
Biliary tract	SNU245	7.3
Biliary tract	SNU308	6.5
Biliary tract	SNU478	6.6
Bone	143B	8.5
Bone	A673	7
Bone	CADOES1	7.5
Bone	CAL78	6.9
Bone	G292CLONEA141B1	6.2
Bone	HOS	8.1
Bone	HS706T	6.6
Bone	HS737T	6.4
Bone	HS819T	6.4
Bone	HS821T	6.8
Bone	HS822T	6.4
Bone	HS863T	6.9
Bone	HS870T	6.6
Bone	HS888T	7.2
Bone	MG63	7.3
Bone	MHHES1	7.1
Bone	OUMS27	7.5
Bone	RDES	7.9
Bone	SJSA1	7.2
Bone	SKES1	6.9
Bone	SKNMC	7.6
Bone	SW1353	6.2
Bone	T173	6.3
Bone	TC71	7
Bone	U2OS	7.8
Breast	AU565	7.7
Breast	BT20	7.4
Breast	BT474	7
Breast	BT483	8.1
Breast	BT549	7.3
Breast	CAL120	7.2
Breast	CAL148	7.1
Breast	CAL51	7.1
Breast	CAL851	6.9
Breast	CAMA1	7.4
Breast	DU4475	6.9
Breast	EFM192A	6.3
Breast	EFM19	8.6
Breast	EVSAT	7.5
Breast	HCC1143	6.8
Breast	HCC1187	6.1
Breast	HCC1395	7.5
Breast	HCC1419	6.7
Breast	HCC1428	8.5
Breast	HCC1500	8.4
Breast	HCC1569	7.5
Breast	HCC1599	7.6
Breast	HCC1806	7.7
Breast	HCC1937	7.8
Breast	HCC1954	7
Breast	HCC202	7.2
Breast	HCC2157	7.9
Breast	HCC2218	7.2
Breast	HCC38	7.4
Breast	HCC70	6.9
Breast	HDQP1	7.5
Breast	HMC18	7
Breast	HS274T	6.5
Breast	HS281T	7.1
Breast	HS343T	7
Breast	HS578T	6.6
Breast	HS606T	6.7
Breast	HS739T	6.8
Breast	HS742T	6.7
Breast	JIMT1	7.8
Breast	KPL1	8.1
Breast	MCF7	8.1
Breast	MDAMB134VI	7.6
Breast	MDAMB157	8
Breast	MDAMB175VII	7.9
Breast	MDAMB231	7.3
Breast	MDAMB361	8
Breast	MDAMB415	7.5
Breast	MDAMB436	7
Breast	MDAMB453	6.9
Breast	MDAMB468	6.7
Breast	SKBR3	7.9
Breast	T47D	7.5
Breast	UACC812	7.9
Breast	UACC893	8.8
Breast	YMB1	7.1
Breast	ZR751	7
Breast	ZR7530	7.5
Central nervous system	1321N1	6.5
Central nervous system	42MGBA	8.1
Central nervous system	8MGBA	6.8
Central nervous system	A172	6.7
Central nervous system	AM38	7.5
Central nervous system	BECKER	7.2
Central nervous system	CAS1	7.3
Central nervous system	CCFSTTG1	6.9
Central nervous system	D283MED	7.5
Central nervous system	D341MED	7.3
Central nervous system	DAOY	6.5
Central nervous system	DBTRG05MG	6.9
Central nervous system	DKMG	6.8
Central nervous system	GAMG	7.3
Central nervous system	GB1	6.4
Central nervous system	GI1	7.5
Central nervous system	GMS10	7.6
Central nervous system	GOS3	6.7
Central nervous system	H4	6.6
Central nervous system	HS683	6.9
Central nervous system	KALS1	6.7
Central nervous system	KG1C	7.6
Central nervous system	KNS42	6.7
Central nervous system	KNS60	7.1
Central nervous system	KNS81	6.7
Central nervous system	KS1	7.2
Central nervous system	LN18	7.3
Central nervous system	LN229	7.3
Central nervous system	M059K	7.2
Central nervous system	MOGGCCM	7
Central nervous system	MOGGUVW	6.9
Central nervous system	NMCG1	7.2
Central nervous system	ONS76	8.1
Central nervous system	SF126	6.9
Central nervous system	SF295	6.7
Central nervous system	SNB19	7.4
Central nervous system	SNU1105	7
Central nervous system	SNU201	7.1
Central nervous system	SNU466	6.9
Central nervous system	SNU489	7.5
Central nervous system	SNU626	7.6
Central nervous system	SNU738	7.8
Central nervous system	SW1088	7.4
Central nervous system	SW1783	6.5
Central nervous system	T98G	7.5
Central nervous system	TM31	6.1
Central nervous system	U118MG	7.4
Central nervous system	U138MG	7.8
Central nervous system	U251MG	7.3
Central nervous system	U87MG	7.4
Central nervous system	YH13	6.5
Central nervous system	YKG1	6.9
Endometrium	AN3CA	7.1
Endometrium	COLO684	7.8
Endometrium	EFE184	6.5
Endometrium	EN	6.6
Endometrium	ESS1	6.9
Endometrium	HEC108	6.8
Endometrium	HEC151	6.9
Endometrium	HEC1A	7
Endometrium	HEC1B	7.4
Endometrium	HEC251	6.6
Endometrium	HEC265	6.9
Endometrium	HEC50B	8.4
Endometrium	HEC59	6.8
Endometrium	HEC6	6.8
Endometrium	ISHIKAWAHERAKLIO02ER	7.6
Endometrium	JHUEM1	6.5
Endometrium	JHUEM2	6.9
Endometrium	JHUEM3	7
Endometrium	KLE	6.4
Endometrium	MFE280	7.8
Endometrium	MFE296	7
Endometrium	MFE319	6
Endometrium	RL952	6.9
Endometrium	SNGM	6.6
Endometrium	SNU1077	7.3
Endometrium	SNU685	7.6
Endometrium	TEN	7.9
Haematopoietic and lymphoid	697	7.7
Haematopoietic and lymphoid	A3KAW	7.8
Haematopoietic and lymphoid	A4FUK	7
Haematopoietic and lymphoid	ALLSIL	8.3
Haematopoietic and lymphoid	AML193	8
Haematopoietic and lymphoid	AMO1	7.2
Haematopoietic and lymphoid	BCP1	7.2
Haematopoietic and lymphoid	BDCM	7.6
Haematopoietic and lymphoid	BL41	7.8
Haematopoietic and lymphoid	BL70	7.7
Haematopoietic and lymphoid	BV173	8.2
Haematopoietic and lymphoid	CA46	7.2
Haematopoietic and lymphoid	CI1	7.4
Haematopoietic and lymphoid	CMK115	7.8
Haematopoietic and lymphoid	CMK86	7.9
Haematopoietic and lymphoid	CMK	7.6
Haematopoietic and lymphoid	CMLT1	8
Haematopoietic and lymphoid	COLO775	6.1
Haematopoietic and lymphoid	DAUDI	7.5
Haematopoietic and lymphoid	DB	7.9
Haematopoietic and lymphoid	DEL	7.4
Haematopoietic and lymphoid	DND41	8.2
Haematopoietic and lymphoid	DOHH2	8
Haematopoietic and lymphoid	EB1	7.2
Haematopoietic and lymphoid	EB2	6.8
Haematopoietic and lymphoid	EHEB	7.8
Haematopoietic and lymphoid	EJM	7
Haematopoietic and lymphoid	EM2	8.5
Haematopoietic and lymphoid	EOL1	7.6
Haematopoietic and lymphoid	F36P	7.1
Haematopoietic and lymphoid	GA10	7.7
Haematopoietic and lymphoid	GDM1	7.3
Haematopoietic and lymphoid	GRANTA519	8
Haematopoietic and lymphoid	HDLM2	6.6
Haematopoietic and lymphoid	HDMYZ	7.2
Haematopoietic and lymphoid	HEL9217	6.8
Haematopoietic and lymphoid	HEL	7
Haematopoietic and lymphoid	HH	7.6
Haematopoietic and lymphoid	HL60	7.8
Haematopoietic and lymphoid	HPBALL	8.7
Haematopoietic and lymphoid	HS604T	6.7
Haematopoietic and lymphoid	HS611T	7.4
Haematopoietic and lymphoid	HS616T	6.4
Haematopoietic and lymphoid	HS751T	6.7
Haematopoietic and lymphoid	HT	7.9
Haematopoietic and lymphoid	HTK	7.9
Haematopoietic and lymphoid	HUNS1	7.2
Haematopoietic and lymphoid	HUT102	7.3
Haematopoietic and lymphoid	HUT78	7.4
Haematopoietic and lymphoid	JEKO1	8.3
Haematopoietic and lymphoid	JK1	7.5
Haematopoietic and lymphoid	JM1	7.9
Haematopoietic and lymphoid	JURKAT	8.6
Haematopoietic and lymphoid	JURLMK1	7.7
Haematopoietic and lymphoid	JVM2	7.7
Haematopoietic and lymphoid	JVM3	7.5
Haematopoietic and lymphoid	K562	7.3
Haematopoietic and lymphoid	KARPAS299	7.2
Haematopoietic and lymphoid	KARPAS422	7.3
Haematopoietic and lymphoid	KARPAS620	7.2
Haematopoietic and lymphoid	KASUMI1	7.5
Haematopoietic and lymphoid	KASUMI2	7.7
Haematopoietic and lymphoid	KASUMI6	7.6
Haematopoietic and lymphoid	KCL22	7
Haematopoietic and lymphoid	KE37	8.5
Haematopoietic and lymphoid	KE97	7.7
Haematopoietic and lymphoid	KG1	7.3
Haematopoietic and lymphoid	KHM1B	7.6
Haematopoietic and lymphoid	KIJK	7.1
Haematopoietic and lymphoid	KMH2	7.3
Haematopoietic and lymphoid	KMM1	8.2
Haematopoietic and lymphoid	KMS11	7.6
Haematopoietic and lymphoid	KMS12BM	7.6
Haematopoietic and lymphoid	KMS18	7.7
Haematopoietic and lymphoid	KMS20	6.8
Haematopoietic and lymphoid	KMS21BM	6.3
Haematopoietic and lymphoid	KMS26	7.6
Haematopoietic and lymphoid	KMS27	7
Haematopoietic and lymphoid	KMS28BM	7.4
Haematopoietic and lymphoid	KMS34	7.5
Haematopoietic and lymphoid	KO52	7.5
Haematopoietic and lymphoid	KOPN8	7.9
Haematopoietic and lymphoid	KU812	7.5
Haematopoietic and lymphoid	KYO1	7.6
Haematopoietic and lymphoid	L1236	6.5
Haematopoietic and lymphoid	L363	6.9
Haematopoietic and lymphoid	L428	7.4
Haematopoietic and lymphoid	L540	7.3
Haematopoietic and lymphoid	LAMA84	7.7
Haematopoietic and lymphoid	LOUCY	7.5
Haematopoietic and lymphoid	LP1	8.1
Haematopoietic and lymphoid	M07E	7.4
Haematopoietic and lymphoid	MC116	7.5
Haematopoietic and lymphoid	ME1	8.1
Haematopoietic and lymphoid	MEC1	7.7
Haematopoietic and lymphoid	MEC2	8.2
Haematopoietic and lymphoid	MEG01	7.2
Haematopoietic and lymphoid	MHHCALL2	7.7
Haematopoietic and lymphoid	MHHCALL3	7.8
Haematopoietic and lymphoid	MHHCALL4	8.1
Haematopoietic and lymphoid	MINO	8
Haematopoietic and lymphoid	MJ	7.3
Haematopoietic and lymphoid	MM1S	6.9
Haematopoietic and lymphoid	MOLM13	7.3
Haematopoietic and lymphoid	MOLM16	6.7
Haematopoietic and lymphoid	MOLM6	7.2
Haematopoietic and lymphoid	MOLP2	7.1
Haematopoietic and lymphoid	MOLP8	7.5
Haematopoietic and lymphoid	MOLT13	8.4
Haematopoietic and lymphoid	MOLT16	7.7
Haematopoietic and lymphoid	MOLT4	8.3
Haematopoietic and lymphoid	MONOMAC1	7.6
Haematopoietic and lymphoid	MONOMAC6	7.6
Haematopoietic and lymphoid	MOTN1	8
Haematopoietic and lymphoid	MUTZ5	8.3
Haematopoietic and lymphoid	MV411	7.2
Haematopoietic and lymphoid	NALM19	7.7
Haematopoietic and lymphoid	NALM1	7.9
Haematopoietic and lymphoid	NALM6	8.2
Haematopoietic and lymphoid	NAMALWA	7.9
Haematopoietic and lymphoid	NB4	7.5
Haematopoietic and lymphoid	NCIH929	7.4
Haematopoietic and lymphoid	NCO2	7
Haematopoietic and lymphoid	NOMO1	7.2
Haematopoietic and lymphoid	NUDHL1	6.9
Haematopoietic and lymphoid	NUDUL1	7.3
Haematopoietic and lymphoid	OCIAML2	7.8
Haematopoietic and lymphoid	OCIAML3	7.3
Haematopoietic and lymphoid	OCIAML5	7.5
Haematopoietic and lymphoid	OCILY10	7
Haematopoietic and lymphoid	OCILY19	8
Haematopoietic and lymphoid	OCILY3	7.7
Haematopoietic and lymphoid	OCIM1	7
Haematopoietic and lymphoid	OPM2	7.2
Haematopoietic and lymphoid	P12ICHIKAWA	9
Haematopoietic and lymphoid	P31FUJ	6.6
Haematopoietic and lymphoid	P3HR1	7.2
Haematopoietic and lymphoid	PCM6	6.7
Haematopoietic and lymphoid	PEER	8.1
Haematopoietic and lymphoid	PF382	9.5
Haematopoietic and lymphoid	PFEIFFER	7.7
Haematopoietic and lymphoid	PL21	7.8
Haematopoietic and lymphoid	RAJI	7.3
Haematopoietic and lymphoid	RCHACV	7.8
Haematopoietic and lymphoid	REC1	7.1
Haematopoietic and lymphoid	REH	7.5
Haematopoietic and lymphoid	RI1	7.8
Haematopoietic and lymphoid	RL	7.7
Haematopoietic and lymphoid	RPMI8226	6.8
Haematopoietic and lymphoid	RPMI8402	8.7
Haematopoietic and lymphoid	RS411	7.5
Haematopoietic and lymphoid	SEM	7.5
Haematopoietic and lymphoid	SET2	7.2
Haematopoietic and lymphoid	SIGM5	7.8
Haematopoietic and lymphoid	SKM1	7.5
Haematopoietic and lymphoid	SKMM2	7.4
Haematopoietic and lymphoid	SR786	8.1
Haematopoietic and lymphoid	ST486	7.4
Haematopoietic and lymphoid	SUDHL10	7.8
Haematopoietic and lymphoid	SUDHL1	8.4
Haematopoietic and lymphoid	SUDHL4	7.7
Haematopoietic and lymphoid	SUDHL5	7.7
Haematopoietic and lymphoid	SUDHL6	8
Haematopoietic and lymphoid	SUDHL8	9
Haematopoietic and lymphoid	SUPB15	7.4
Haematopoietic and lymphoid	SUPHD1	7.4
Haematopoietic and lymphoid	SUPM2	7
Haematopoietic and lymphoid	SUPT11	8
Haematopoietic and lymphoid	SUPT1	7.6
Haematopoietic and lymphoid	TALL1	9.1
Haematopoietic and lymphoid	TF1	6.2
Haematopoietic and lymphoid	THP1	7.2
Haematopoietic and lymphoid	TO175T	6.7
Haematopoietic and lymphoid	TOLEDO	7.7
Haematopoietic and lymphoid	U266B1	6.7
Haematopoietic and lymphoid	U937	6.9
Haematopoietic and lymphoid	UT7	7.8
Haematopoietic and lymphoid	WSUDLCL2	7.9
Kidney	769P	7.3
Kidney	786O	7.4
Kidney	A498	6.9
Kidney	A704	7
Kidney	ACHN	6.4
Kidney	BFTC909	7.8
Kidney	CAKI1	6.8
Kidney	CAKI2	6.7
Kidney	CAL54	7.2
Kidney	KMRC1	6.4
Kidney	KMRC20	7.2
Kidney	KMRC2	6.8
Kidney	KMRC3	7.1
Kidney	OSRC2	6.9
Kidney	RCC10RGB	7.9
Kidney	SNU1272	7
Kidney	SNU349	6.5
Kidney	TUHR10TKB	7
Kidney	TUHR14TKB	6.9
Kidney	TUHR4TKB	7.7
Kidney	VMRCRCW	7.7
Kidney	VMRCRCZ	7.2
Large intestine	C2BBE1	8.3
Large intestine	CCK81	6.6
Large intestine	CL11	7.1
Large intestine	CL14	8.1
Large intestine	CL34	7.2
Large intestine	CL40	6.8
Large intestine	COLO205	7.5
Large intestine	COLO320	7.8
Large intestine	COLO678	8.3
Large intestine	CW2	7.3
Large intestine	DLD1	7
Large intestine	GP2D	7.3
Large intestine	HCC56	8.7
Large intestine	HCT116	7.2
Large intestine	HCT15	7
Large intestine	HS675T	6.6
Large intestine	HS698T	6.3
Large intestine	HT115	6.8
Large intestine	HT29	8
Large intestine	HT55	6.8
Large intestine	KM12	7
Large intestine	LOVO	6.9
Large intestine	LS1034	7.7
Large intestine	LS123	7.5
Large intestine	LS180	7.3
Large intestine	LS411N	6.8
Large intestine	LS513	6.9
Large intestine	MDST8	8
Large intestine	NCIH508	8.1
Large intestine	NCIH716	8.1
Large intestine	NCIH747	8.4
Large intestine	OUMS23	7.2
Large intestine	RCM1	8.5
Large intestine	RKO	7.7
Large intestine	SKCO1	7.8
Large intestine	SNU1040	7.3
Large intestine	SNU1197	7.5
Large intestine	SNU175	6.8
Large intestine	SNU283	7.8
Large intestine	SNU407	6.4
Large intestine	SNU503	7.2
Large intestine	SNU61	6.6
Large intestine	SNU81	7
Large intestine	SNUC1	8.4
Large intestine	SNUC2A	6.7
Large intestine	SNUC4	6.7
Large intestine	SNUC5	7.6
Large intestine	SW1116	7.9
Large intestine	SW1417	7.9
Large intestine	SW1463	7.9
Large intestine	SW403	8.4
Large intestine	SW480	7.3
Large intestine	SW48	6.8
Large intestine	SW620	7.7
Large intestine	SW837	8
Large intestine	SW948	8.3
Large intestine	T84	7.1
Liver	ALEXANDERCELLS	6.4
Liver	C3A	8
Liver	HEP3B217	7.4
Liver	HEPG2	7.9
Liver	HLE	7.6
Liver	HLF	7
Liver	HUH1	7.4
Liver	HUH6	7.7
Liver	HUH7	6.9
Liver	JHH1	7.1
Liver	JHH2	7
Liver	JHH4	6.9
Liver	JHH5	7.6
Liver	JHH6	7.1
Liver	JHH7	7.5
Liver	LI7	6.6
Liver	PLCPRF5	6.5
Liver	SKHEP1	6.4
Liver	SNU182	7.4
Liver	SNU387	7.5
Liver	SNU398	7.7
Liver	SNU423	7.6
Liver	SNU449	7.3
Liver	SNU475	7.3
Liver	SNU761	7
Liver	SNU878	6.2
Liver	SNU886	6.5
Lung	A549	6.3
Lung	ABC1	7.3
Lung	BEN	7.7
Lung	CAL12T	7.2
Lung	CALU1	7.2
Lung	CALU3	7
Lung	CALU6	7
Lung	CHAGOK1	7.9
Lung	COLO668	6.7
Lung	COLO699	7.4
Lung	CORL105	6.8
Lung	CORL23	7.1
Lung	CORL24	8.3
Lung	CORL279	7.2
Lung	CORL311	8.4
Lung	CORL47	7.7
Lung	CORL51	7.5
Lung	CORL88	8
Lung	CORL95	7.9
Lung	CPCN	8.3
Lung	DMS114	7.5
Lung	DMS153	6.9
Lung	DMS273	7.5
Lung	DMS454	7.3
Lung	DMS53	6.8
Lung	DMS79	7.6
Lung	DV90	6.4
Lung	EBC1	7.4
Lung	EPLC272H	7.3
Lung	HARA	7.3
Lung	HCC1171	8.8
Lung	HCC1195	7.9
Lung	HCC15	5.8
Lung	HCC2279	7
Lung	HCC2935	6.7
Lung	HCC33	8.8
Lung	HCC366	7.9
Lung	HCC4006	6.9
Lung	HCC44	7.5
Lung	HCC78	7.2
Lung	HCC827	7.4
Lung	HCC95	7.7
Lung	HLC1	7.4
Lung	HLFA	6.6
Lung	HS229T	6.9
Lung	HS618T	6.9
Lung	IALM	7.1
Lung	KNS62	7.1
Lung	LC1F	6.6
Lung	LC1SQSF	6.8
Lung	LCLC103H	7.2
Lung	LCLC97TM1	7.2
Lung	LK2	7
Lung	LOUNH91	7.8
Lung	LU65	6.4
Lung	LU99	7.4
Lung	LUDLU1	7.5
Lung	LXF289	7.3
Lung	MORCPR	7.4
Lung	NCIH1048	7
Lung	NCIH1092	7.6
Lung	NCIH1105	7.9
Lung	NCIH1155	7.1
Lung	NCIH1184	7.3
Lung	NCIH1299	7.4
Lung	NCIH1339	7.9
Lung	NCIH1341	6.8
Lung	NCIH1355	6.1
Lung	NCIH1373	6.8
Lung	NCIH1385	7.4
Lung	NCIH1395	6.9
Lung	NCIH1435	7.3
Lung	NCIH1436	7.8
Lung	NCIH1437	6.7
Lung	NCIH146	7.3
Lung	NCIH1563	6.6
Lung	NCIH1568	6.8
Lung	NCIH1573	7
Lung	NCIH1581	7.5
Lung	NCIH1618	8.2
Lung	NCIH1623	6.7
Lung	NCIH1648	7.8
Lung	NCIH1650	7.8
Lung	NCIH1651	6.8
Lung	NCIH1666	8
Lung	NCIH1693	8
Lung	NCIH1694	7
Lung	NCIH1703	6.4
Lung	NCIH1734	6.3
Lung	NCIH1755	7.4
Lung	NCIH1781	7.1
Lung	NCIH1792	6.9
Lung	NCIH1793	7.5
Lung	NCIH1836	7.4
Lung	NCIH1838	7.3
Lung	NCIH1869	6.4
Lung	NCIH1876	7.9
Lung	NCIH1915	7.1
Lung	NCIH1930	7.3
Lung	NCIH1944	6.7
Lung	NCIH1963	7.7
Lung	NCIH196	7.3
Lung	NCIH1975	6.7
Lung	NCIH2009	6.8
Lung	NCIH2023	6
Lung	NCIH2029	7.7
Lung	NCIH2030	7.3
Lung	NCIH2066	7.2
Lung	NCIH2081	6.8
Lung	NCIH2085	8
Lung	NCIH2087	6.5
Lung	NCIH209	7.4
Lung	NCIH2106	8.2
Lung	NCIH2110	6.8
Lung	NCIH211	7.6
Lung	NCIH2122	6.4
Lung	NCIH2126	7.2
Lung	NCIH2141	8.2
Lung	NCIH2170	7.3
Lung	NCIH2171	7.5
Lung	NCIH2172	7.8
Lung	NCIH2196	7.2
Lung	NCIH2227	7.4
Lung	NCIH2228	6.3
Lung	NCIH226	6.9
Lung	NCIH2286	7.2
Lung	NCIH2291	6.3
Lung	NCIH2342	7.5
Lung	NCIH2347	7
Lung	NCIH23	7.7
Lung	NCIH2405	7.6
Lung	NCIH2444	7.2
Lung	NCIH292	7.7
Lung	NCIH322	7.5
Lung	NCIH3255	7.5
Lung	NCIH358	7.5
Lung	NCIH441	7.9
Lung	NCIH446	7
Lung	NCIH460	6.3
Lung	NCIH510	7.2
Lung	NCIH520	6.8
Lung	NCIH522	7.7
Lung	NCIH524	7.8
Lung	NCIH526	8.2
Lung	NCIH596	7.5
Lung	NCIH647	6.7
Lung	NCIH650	7.5
Lung	NCIH661	7.4
Lung	NCIH69	6.5
Lung	NCIH727	6.3
Lung	NCIH810	6.8
Lung	NCIH82	6.9
Lung	NCIH838	7.6
Lung	NCIH841	7.2
Lung	NCIH854	7.9
Lung	NCIH889	7.3
Lung	PC14	6.5
Lung	RERFLCAD1	7.7
Lung	RERFLCAD2	7.2
Lung	RERFLCAI	6.7
Lung	RERFLCKJ	6.7
Lung	RERFLCMS	6.1
Lung	RERFLCSQ1	7.4
Lung	SBC5	6.9
Lung	SCLC21H	8
Lung	SHP77	7.7
Lung	SKLU1	6.5
Lung	SKMES1	5.9
Lung	SQ1	7
Lung	SW1271	8.1
Lung	SW1573	7.4
Lung	SW900	7.2
Lung	VMRCLCD	7.2
Lung	VMRCLCP	7.7
Oesophagus	COLO680N	7.2
Oesophagus	ECGI10	6.8
Oesophagus	KYSE140	6.7
Oesophagus	KYSE150	7.1
Oesophagus	KYSE180	7.1
Oesophagus	KYSE270	7.9
Oesophagus	KYSE30	6.9
Oesophagus	KYSE410	7.4
Oesophagus	KYSE450	7.1
Oesophagus	KYSE510	6.9
Oesophagus	KYSE520	7.6
Oesophagus	KYSE70	7.1
Oesophagus	OE19	7.7
Oesophagus	OE33	7.7
Oesophagus	TE10	8
Oesophagus	TE11	7.3
Oesophagus	TE14	6.6
Oesophagus	TE15	7.3
Oesophagus	TE1	7.8
Oesophagus	TE4	6.9
Oesophagus	TE5	8.3
Oesophagus	TE6	7.1
Oesophagus	TE8	8.3
Oesophagus	TE9	7
Oesophagus	TT	6.8
Ovary	59M	7.2
Ovary	A2780	6.9
Ovary	CAOV3	7.1
Ovary	CAOV4	7.7
Ovary	COLO704	7.8
Ovary	COV318	7.3
Ovary	COV362	6.8
Ovary	COV434	7.1
Ovary	COV504	7.3
Ovary	COV644	7.2
Ovary	EFO21	7.3
Ovary	EFO27	7.3
Ovary	ES2	7.1
Ovary	FUOV1	7.7
Ovary	HEYA8	7.1
Ovary	HS571T	6.1
Ovary	IGROV1	6.3
Ovary	JHOC5	7.5
Ovary	JHOM1	7.2
Ovary	JHOM2B	8.5
Ovary	JHOS2	8.1
Ovary	JHOS4	7.6
Ovary	KURAMOCHI	8.7
Ovary	MCAS	6.7
Ovary	NIHOVCAR3	7.7
Ovary	OAW28	6.8
Ovary	OAW42	8.1
Ovary	OC314	7.1
Ovary	OC316	7.2
Ovary	ONCODG1	8
Ovary	OV56	6.5
Ovary	OV7	6.8
Ovary	OV90	6.9
Ovary	OVCAR4	6.6
Ovary	OVCAR8	7.4
Ovary	OVISE	6.3
Ovary	OVK18	7.5
Ovary	OVKATE	7.5
Ovary	OVMANA	7.8
Ovary	OVSAHO	7.4
Ovary	OVTOKO	6.3
Ovary	RMGI	6.7
Ovary	RMUGS	6.5
Ovary	SKOV3	6.8
Ovary	SNU119	7
Ovary	SNU840	7
Ovary	SNU8	7
Ovary	TOV112D	6.8
Ovary	TOV21G	6.3
Ovary	TYKNU	7
Pancreas	ASPC1	7.5
Pancreas	BXPC3	7.2
Pancreas	CAPAN1	7.3
Pancreas	CAPAN2	7.3
Pancreas	CFPAC1	6.9
Pancreas	DANG	7.2
Pancreas	HPAC	7.7
Pancreas	HPAFII	7.2
Pancreas	HS766T	8.4
Pancreas	HUPT3	7.1
Pancreas	HUPT4	7.3
Pancreas	KCIMOH1	6.8
Pancreas	KLM1	7.4
Pancreas	KP2	7.9
Pancreas	KP3	7.3
Pancreas	KP4	7.4
Pancreas	L33	7.6
Pancreas	MIAPACA2	7.2
Pancreas	PANC0203	7.5
Pancreas	PANC0213	7.1
Pancreas	PANC0327	7.7
Pancreas	PANC0403	7.5
Pancreas	PANC0504	7.6
Pancreas	PANC0813	6.9
Pancreas	PANC1005	7.6
Pancreas	PANC1	7.2
Pancreas	PATU8902	7.6
Pancreas	PATU8988S	7.8
Pancreas	PATU8988T	8
Pancreas	PK1	7.4
Pancreas	PK45H	7
Pancreas	PK59	8
Pancreas	PL45	7.4
Pancreas	PSN1	7.6
Pancreas	QGP1	6.5
Pancreas	SNU213	7.5
Pancreas	SNU324	6.5
Pancreas	SNU410	7.6
Pancreas	SU8686	7.9
Pancreas	SUIT2	7.6
Pancreas	SW1990	8.1
Pancreas	T3M4	7.4
Pancreas	TCCPAN2	8
Pancreas	YAPC	7.7
Pleura	ACCMESO1	7.3
Pleura	DM3	7
Pleura	ISTMES1	7.2
Pleura	ISTMES2	6.5
Pleura	JL1	7.5
Pleura	MPP89	7.3
Pleura	MSTO211H	6.4
Pleura	NCIH2052	7.4
Pleura	NCIH2452	6.9
Pleura	NCIH28	7.2
Prostate	22RV1	7
Prostate	DU145	6.6
Prostate	LNCAPCLONEFGC	7.1
Prostate	MDAPCA2B	7.1
Prostate	NCIH660	7.4
Prostate	PC3	6.6
Prostate	VCAP	7.3
Salivary gland	A253	7.2
Salivary gland	YD15	7.4
Skin	A101D	6.8
Skin	A2058	6.6
Skin	A375	7.1
Skin	C32	6.8
Skin	CHL1	5.9
Skin	CJM	7
Skin	COLO679	7.1
Skin	COLO741	7
Skin	COLO783	7
Skin	COLO792	6.7
Skin	COLO800	7.5
Skin	COLO818	7.1
Skin	COLO829	6.8
Skin	COLO849	7.3
Skin	G361	6.9
Skin	GRM	8
Skin	HMCB	6.2
Skin	HS294T	6.7
Skin	HS600T	6.3
Skin	HS688AT	6.8
Skin	HS695T	7.8
Skin	HS839T	6.5
Skin	HS852T	6.8
Skin	HS895T	6.6
Skin	HS934T	7.1
Skin	HS936T	7.2
Skin	HS939T	6.7
Skin	HS940T	6.9
Skin	HS944T	6.4
Skin	HT144	7.8
Skin	IGR1	7.2
Skin	IGR37	7
Skin	IGR39	7.3
Skin	IPC298	6.9
Skin	K029AX	6.7
Skin	LOXIMVI	7.5
Skin	MALME3M	6.7
Skin	MDAMB435S	7.5
Skin	MELHO	7.4
Skin	MELJUSO	7
Skin	MEWO	7.1
Skin	RPMI7951	7.4
Skin	RVH421	7.5
Skin	SH4	6.9
Skin	SKMEL1	8.3
Skin	SKMEL24	6.7
Skin	SKMEL28	7.4
Skin	SKMEL2	7
Skin	SKMEL30	7.1
Skin	SKMEL31	7
Skin	SKMEL3	8
Skin	SKMEL5	6.8
Skin	UACC257	7.3
Skin	UACC62	6.7
Skin	WM115	6.9
Skin	WM1799	7.5
Skin	WM2664	6.5
Skin	WM793	7.9
Skin	WM88	7.4
Skin	WM983B	7.8
Small intestine	HUTU80	7.3
Soft tissue	A204	7.2
Soft tissue	G401	7.6
Soft tissue	G402	7.2
Soft tissue	GCT	7.2
Soft tissue	HS729	6.9
Soft tissue	HT1080	7
Soft tissue	KYM1	7.2
Soft tissue	MESSA	7
Soft tissue	RD	7.4
Soft tissue	RH30	7.3
Soft tissue	RH41	8.9
Soft tissue	RKN	8
Soft tissue	S117	7.3
Soft tissue	SJRH30	8.8
Soft tissue	SKLMS1	7
Soft tissue	SKUT1	7.1
Soft tissue	TE125T	6.4
Soft tissue	TE159T	6.6
Soft tissue	TE441T	8.6
Soft tissue	TE617T	7
Stomach	2313287	7.3
Stomach	AGS	7.2
Stomach	AZ521	7.2
Stomach	ECC10	7.6
Stomach	ECC12	7.5
Stomach	FU97	8
Stomach	GCIY	6.3
Stomach	GSS	8
Stomach	GSU	6.9
Stomach	HGC27	7
Stomach	HS746T	7.3
Stomach	HUG1N	7.1
Stomach	IM95	7
Stomach	KATOIII	7.5
Stomach	KE39	7.2
Stomach	LMSU	6.9
Stomach	MKN1	7.3
Stomach	MKN45	7.8
Stomach	MKN74	5.7
Stomach	MKN7	7.9
Stomach	NCCSTCK140	8.2
Stomach	NCIN87	7.6
Stomach	NUGC2	6.8
Stomach	NUGC3	7.8
Stomach	NUGC4	6.5
Stomach	OCUM1	6.3
Stomach	RERFGC1B	7.3
Stomach	SH10TC	7.1
Stomach	SNU16	6.7
Stomach	SNU1	8.1
Stomach	SNU216	8.5
Stomach	SNU520	6.7
Stomach	SNU5	7.1
Stomach	SNU601	7.8
Stomach	SNU620	7.6
Stomach	SNU668	7.7
Stomach	SNU719	7.6
Stomach	TGBC11TKB	6.8
Thyroid	8305C	7.5
Thyroid	8505C	7.7
Thyroid	BCPAP	8.6
Thyroid	BHT101	7.1
Thyroid	CAL62	8.5
Thyroid	CGTHW1	7.2
Thyroid	FTC133	6.4
Thyroid	FTC238	7.2
Thyroid	ML1	6.8
Thyroid	SW579	6.7
Thyroid	TT2609C02	6.6
Thyroid	TT	6.4
Upper aerodigestive tract	BHY	8.2
Upper aerodigestive tract	BICR16	6.5
Upper aerodigestive tract	BICR18	7.1
Upper aerodigestive tract	BICR22	7.3
Upper aerodigestive tract	BICR31	7.4
Upper aerodigestive tract	BICR56	7
Upper aerodigestive tract	BICR6	7.3
Upper aerodigestive tract	CAL27	7.7
Upper aerodigestive tract	CAL33	8.2
Upper aerodigestive tract	DETROIT562	7.3
Upper aerodigestive tract	FADU	7.6
Upper aerodigestive tract	HS840T	6.5
Upper aerodigestive tract	HSC2	8.3
Upper aerodigestive tract	HSC3	7
Upper aerodigestive tract	HSC4	7.9
Upper aerodigestive tract	PECAPJ15	8
Upper aerodigestive tract	PECAPJ34CLONEC12	7.4
Upper aerodigestive tract	PECAPJ41CLONED2	6.8
Upper aerodigestive tract	PECAPJ49	7.7
Upper aerodigestive tract	SCC15	7.3
Upper aerodigestive tract	SCC25	6.8
Upper aerodigestive tract	SCC4	7.1
Upper aerodigestive tract	SCC9	7.4
Upper aerodigestive tract	SNU1076	7.6
Upper aerodigestive tract	SNU1214	6.8
Upper aerodigestive tract	SNU46	7.4
Upper aerodigestive tract	SNU899	7.6
Upper aerodigestive tract	YD10B	8.3
Upper aerodigestive tract	YD38	7.5
Upper aerodigestive tract	YD8	7.4
Urinary tract	5637	7.4
Urinary tract	639V	7.8
Urinary tract	647V	7.9
Urinary tract	BC3C	7.3
Urinary tract	BFTC905	7.4
Urinary tract	CAL29	7.5
Urinary tract	HS172T	6.4
Urinary tract	HT1197	6.5
Urinary tract	HT1376	7.6
Urinary tract	J82	7.2
Urinary tract	JMSU1	7.2
Urinary tract	KMBC2	7.1
Urinary tract	KU1919	8
Urinary tract	RT11284	7.9
Urinary tract	RT112	7.9
Urinary tract	RT4	7
Urinary tract	SCABER	6.8
Urinary tract	SW1710	7.4
Urinary tract	SW780	7.6
Urinary tract	T24	7.9
Urinary tract	TCCSUP	7.1
Urinary tract	UMUC1	7.7
Urinary tract	UMUC3	7.7
Urinary tract	VMCUB1	8.2

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	22.2
Adrenal gland	18.8
Appendix	29.5
Bone marrow	17.6
Breast	30.8
Cerebral cortex	23.1
Cervix, uterine	26.6
Colon	19.1
Duodenum	20.2
Endometrium	47.3
Epididymis	32.1
Esophagus	19.9
Fallopian tube	47.7
Gallbladder	27.5
Heart muscle	16.9
Kidney	15.4
Liver	7.6
Lung	31
Lymph node	37.5
Ovary	45.8
Pancreas	3.7
Parathyroid gland	44.1
Placenta	35.5
Prostate	37.6
Rectum	21.9
Salivary gland	12.5
Seminal vesicle	34.5
Skeletal muscle	9.1
Skin	43.2
Small intestine	24.7
Smooth muscle	30.7
Spleen	40.6
Stomach	21.5
Testis	37.5
Thyroid gland	37.8
Tonsil	25.7
Urinary bladder	19.7

> Text Mining based Expression

[ TOP ]

PMID	Expression	Cancer	Evidence
22469980	Overexpression	Melanoma	An analysis of Dido1 expression revealed an upregulation of Dido1 levels in melanoma cell lines and tissues compared with normal melanocytes.

Summary
Symbol	DIDO1
Name	death inducer-obliterator 1
Aliases	dJ885L7.8; FLJ11265; KIAA0333; DIO-1; BYE1; C20orf158; DATF1; chromosome 20 open reading frame 158; death as ......
Location	20q13.33
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.58	1.04e-37	5.9	38.4	55.7	Gain
BRCA	Breast invasive carcinoma	1075	0.697	3.87e-157	4.6	47.2	48.3	Gain
CESC	Cervical and endocervical cancers	292	0.57	1.42e-26	4.8	52.4	42.8	Gain
COAD	Colon adenocarcinoma	449	0.738	1.61e-78	0.2	27.8	71.9	Gain
ESCA	Esophageal carcinoma	183	0.511	1.53e-13	3.3	33.3	63.4	Gain
GBM	Glioblastoma multiforme	147	0.469	2.12e-09	2	61.2	36.7	Gain
HNSC	Head and Neck squamous cell carcinoma	514	0.41	3.22e-22	6.6	55.3	38.1	Gain
KIRC	Kidney renal clear cell carcinoma	525	0.217	4.99e-07	0	77	23	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	0.549	4.13e-24	0	64.6	35.4	Gain
LAML	Acute Myeloid Leukemia	166	0.16	0.04	0	98.8	1.2	Neutral
LGG	Brain Lower Grade Glioma	513	0.356	8.15e-17	1.2	89.1	9.7	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.499	2.33e-24	2.2	63.5	34.3	Gain
LUAD	Lung adenocarcinoma	512	0.612	5.09e-54	9	44.5	46.5	Gain
LUSC	Lung squamous cell carcinoma	498	0.491	1.24e-31	12.4	38.2	49.4	Gain
OV	Ovarian serous cystadenocarcinoma	300	0.639	8.13e-36	4.7	24.7	70.7	Gain
PAAD	Pancreatic adenocarcinoma	177	0.434	1.65e-09	4	70.6	25.4	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	0.336	1.2e-05	1.9	92	6.2	Neutral
PRAD	Prostate adenocarcinoma	491	0.31	2.23e-12	1.2	90.6	8.1	Neutral
READ	Rectum adenocarcinoma	164	0.66	7.51e-22	1.2	11	87.8	Gain
SARC	Sarcoma	255	0.383	2.46e-10	11.4	52.5	36.1	Gain
SKCM	Skin Cutaneous Melanoma	367	0.677	1.82e-50	1.6	47.1	51.2	Gain
STAD	Stomach adenocarcinoma	413	0.725	1.37e-68	1.7	32.9	65.4	Gain
TGCT	Testicular Germ Cell Tumors	150	0.259	0.00139	9.3	62.7	28	Neutral
THCA	Thyroid carcinoma	497	0.117	0.00893	0	97.6	2.4	Neutral
THYM	Thymoma	119	-0.07	0.448	0.8	90.8	8.4	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.554	1.61e-44	2	69.6	28.3	Neutral

Summary
Symbol	DIDO1
Name	death inducer-obliterator 1
Aliases	dJ885L7.8; FLJ11265; KIAA0333; DIO-1; BYE1; C20orf158; DATF1; chromosome 20 open reading frame 158; death as ......
Location	20q13.33
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

[ TOP ]

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.31	8.64e-11	17	408	-0.009	0.00526	NS/NA
BRCA	Breast invasive carcinoma	-0.267	1.63e-15	83	785	-0.007	5.09e-05	NS/NA
CESC	Cervical and endocervical cancers	-0.457	0	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.453	0	19	297	-0.005	0.0232	NS/NA
ESCA	Esophageal carcinoma	-0.315	8.66e-06	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.224	0.0727	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.225	1.25e-07	20	522	0.004	0.0251	NS/NA
KIRC	Kidney renal clear cell carcinoma	-0.163	0.00244	24	319	-0.055	0.0434	NS/NA
KIRP	Kidney renal papillary cell carcinoma	-0.346	1.09e-09	23	275	0.003	0.563	NS/NA
LAML	Acute Myeloid Leukemia	-0.176	0.0221	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	-0.149	0.000584	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.212	1.37e-05	41	373	0.003	0.433	NS/NA
LUAD	Lung adenocarcinoma	-0.172	0.000161	21	456	-0.005	0.56	NS/NA
LUSC	Lung squamous cell carcinoma	-0.214	2.78e-05	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	-0.583	0.108	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.15	0.0427	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.317	1.12e-05	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.127	0.00326	35	498	0.001	0.247	NS/NA
READ	Rectum adenocarcinoma	-0.498	1.77e-07	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.282	3.84e-06	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.288	2.22e-10	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.412	0	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.511	0	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.254	1.24e-09	50	509	0.131	1.26e-15	NS/NA
THYM	Thymoma	-0.208	0.0215	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.306	2.02e-11	34	431	0.018	0.647	NS/NA

Summary
Symbol	DIDO1
Name	death inducer-obliterator 1
Aliases	dJ885L7.8; FLJ11265; KIAA0333; DIO-1; BYE1; C20orf158; DATF1; chromosome 20 open reading frame 158; death as ......
Location	20q13.33
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Level	Level Name
Adrenal gland	3	High
Appendix	3	High
Bone marrow	3	High
Breast	3	High
Bronchus	3	High
Caudate	3	High
Cerebellum	3	High
Cerebral cortex	3	High
Cervix, uterine	3	High
Colon	3	High
Duodenum	3	High
Endometrium	3	High
Epididymis	3	High
Esophagus	3	High
Fallopian tube	3	High
Gallbladder	3	High
Heart muscle	3	High
Hippocampus	3	High
Kidney	3	High
Liver	3	High
Lung	3	High
Lymph node	3	High
Nasopharynx	3	High
Oral mucosa	3	High
Ovary	3	High
Pancreas	3	High
Parathyroid gland	3	High
Placenta	3	High
Prostate	3	High
Rectum	3	High
Salivary gland	3	High
Seminal vesicle	3	High
Skeletal muscle	3	High
Skin	3	High
Small intestine	3	High
Smooth muscle	3	High
Soft tissue	3	High
Spleen	3	High
Stomach	3	High
Testis	3	High
Thyroid gland	3	High
Tonsil	3	High
Urinary bladder	3	High
Vagina	3	High

Summary
Symbol	DIDO1
Name	death inducer-obliterator 1
Aliases	dJ885L7.8; FLJ11265; KIAA0333; DIO-1; BYE1; C20orf158; DATF1; chromosome 20 open reading frame 158; death as ......
Location	20q13.33
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.666	NS	24476821
BRCA	Breast invasive carcinoma	521	1.62e-09	Significant	23000897
COAD	Colon adenocarcinoma	149	1.86e-14	Significant	22810696
GBM	Glioblastoma multiforme	157	8.16e-05	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	0.025	Significant	25631445
KIRP	Kidney renal papillary cell carcinoma	161	7.34e-05	Significant	26536169
LGG	Brain Lower Grade Glioma	513	0.000417	Significant	26824661
LUAD	Lung adenocarcinoma	230	0.0249	Significant	25079552
LUSC	Lung squamous cell carcinoma	178	0.000776	Significant	22960745
OV	Ovarian serous cystadenocarcinoma	287	0.000192	Significant	21720365
PRAD	Prostate adenocarcinoma	333	5.52e-09	Significant	26544944
READ	Rectum adenocarcinoma	67	0.000186	Significant	22810696
SKCM	Skin Cutaneous Melanoma	315	0.144	NS	26091043
STAD	Stomach adenocarcinoma	277	2.8e-16	Significant	25079317
THCA	Thyroid carcinoma	391	0.149	NS	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	0.000203	Significant	23636398

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	0.875	0.527	NS
BRCA	Breast invasive carcinoma	1079	1.333	0.223	NS
CESC	Cervical and endocervical cancers	291	1.082	0.813	NS
COAD	Colon adenocarcinoma	439	1.29	0.37	NS
ESCA	Esophageal carcinoma	184	0.862	0.64	NS
GBM	Glioblastoma multiforme	158	0.905	0.697	NS
HNSC	Head and Neck squamous cell carcinoma	518	0.804	0.26	NS
KIRC	Kidney renal clear cell carcinoma	531	1.149	0.515	NS
KIRP	Kidney renal papillary cell carcinoma	287	0.473	0.0765	NS
LAML	Acute Myeloid Leukemia	149	0.942	0.854	NS
LGG	Brain Lower Grade Glioma	511	1.657	0.0402	Shorter
LIHC	Liver hepatocellular carcinoma	365	0.97	0.905	NS
LUAD	Lung adenocarcinoma	502	0.617	0.018	Longer
LUSC	Lung squamous cell carcinoma	494	1.007	0.971	NS
OV	Ovarian serous cystadenocarcinoma	303	0.815	0.331	NS
PAAD	Pancreatic adenocarcinoma	177	0.346	0.000344	Longer
PCPG	Pheochromocytoma and Paraganglioma	179	690125897.093	0.0633	NS
PRAD	Prostate adenocarcinoma	497	1.75	0.54	NS
READ	Rectum adenocarcinoma	159	0.46	0.155	NS
SARC	Sarcoma	259	0.825	0.503	NS
SKCM	Skin Cutaneous Melanoma	459	1.366	0.107	NS
STAD	Stomach adenocarcinoma	388	0.872	0.559	NS
TGCT	Testicular Germ Cell Tumors	134	1584748929.225	0.161	NS
THCA	Thyroid carcinoma	500	0.986	0.981	NS
THYM	Thymoma	119	0.209	0.145	NS
UCEC	Uterine Corpus Endometrial Carcinoma	543	1.337	0.346	NS

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	-0.136	0.00617	Lower
BRCA	Breast invasive carcinoma	1071	0.06	0.0512	NS
CESC	Cervical and endocervical cancers	167	0.057	0.467	NS
COAD	Colon adenocarcinoma	445	0.132	0.00523	Higher
ESCA	Esophageal carcinoma	162	0.035	0.661	NS
HNSC	Head and Neck squamous cell carcinoma	448	-0.134	0.00446	Lower
KIRC	Kidney renal clear cell carcinoma	531	-0.054	0.213	NS
KIRP	Kidney renal papillary cell carcinoma	260	-0.108	0.0824	NS
LIHC	Liver hepatocellular carcinoma	347	0.089	0.0965	NS
LUAD	Lung adenocarcinoma	507	-0.097	0.0295	Lower
LUSC	Lung squamous cell carcinoma	497	0.004	0.925	NS
OV	Ovarian serous cystadenocarcinoma	302	-0.019	0.742	NS
PAAD	Pancreatic adenocarcinoma	176	-0.073	0.336	NS
READ	Rectum adenocarcinoma	156	0.108	0.178	NS
SKCM	Skin Cutaneous Melanoma	410	-0.082	0.0981	NS
STAD	Stomach adenocarcinoma	392	-0.007	0.885	NS
TGCT	Testicular Germ Cell Tumors	81	-0.102	0.366	NS
THCA	Thyroid carcinoma	499	-0.075	0.0937	NS
UCEC	Uterine Corpus Endometrial Carcinoma	501	0.118	0.00815	Higher

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	-0.015	0.807	NS
HNSC	Head and Neck squamous cell carcinoma	498	0.02	0.651	NS
KIRC	Kidney renal clear cell carcinoma	525	-0.045	0.308	NS
LGG	Brain Lower Grade Glioma	514	0.053	0.229	NS
LIHC	Liver hepatocellular carcinoma	366	0.109	0.0365	Higher
OV	Ovarian serous cystadenocarcinoma	296	-0.05	0.392	NS
PAAD	Pancreatic adenocarcinoma	176	0.029	0.704	NS
STAD	Stomach adenocarcinoma	406	-0.197	6.31e-05	Lower
UCEC	Uterine Corpus Endometrial Carcinoma	534	0.218	3.82e-07	Higher

Summary
Symbol	DIDO1
Name	death inducer-obliterator 1
Aliases	dJ885L7.8; FLJ11265; KIAA0333; DIO-1; BYE1; C20orf158; DATF1; chromosome 20 open reading frame 158; death as ......
Location	20q13.33
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	DIDO1
Name	death inducer-obliterator 1
Aliases	dJ885L7.8; FLJ11265; KIAA0333; DIO-1; BYE1; C20orf158; DATF1; chromosome 20 open reading frame 158; death as ......
Location	20q13.33
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for DIDO1.

Summary
Symbol	DIDO1
Name	death inducer-obliterator 1
Aliases	dJ885L7.8; FLJ11265; KIAA0333; DIO-1; BYE1; C20orf158; DATF1; chromosome 20 open reading frame 158; death as ......
Location	20q13.33
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining

[ TOP ]

PMID	Cancer	Hierarchy	Gene	Relation to CR	Evidence
22469980	Melanoma	downstream	Integrin αV	positive regulation	Finally, we demonstrated that Dido1 induces the expression of Integrin αV, thereby promoting the attachment, migration, invasion and apoptosis resistance of melanoma cells.