CR2Cancer

Summary
Symbol	GTF3C1
Name	general transcription factor IIIC subunit 1
Aliases	TFIIIC220; general transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD ); TFIIIC; TFIIICalpha; TF ......
Location	16p12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

[ TOP ]

Domain

PF04182 B-block binding subunit of TFIIIC

Function

Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. Binds to the box B promoter element.

Classification

Class	Modification	Substrate	Product	PubMed
#	#	#	#	#

> Gene Ontology [ TOP ]
Biological Process	GO:0006383 transcription from RNA polymerase III promoter GO:0006399 tRNA metabolic process GO:0009303 rRNA transcription GO:0009304 tRNA transcription GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter GO:0042797 tRNA transcription from RNA polymerase III promoter GO:0098781 ncRNA transcription
Molecular Function	-
Cellular Component	GO:0000127 transcription factor TFIIIC complex GO:0005667 transcription factor complex GO:0044798 nuclear transcription factor complex GO:0090576 RNA polymerase III transcription factor complex

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	R-HSA-74160: Gene Expression R-HSA-504046: RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription R-HSA-749476: RNA Polymerase III Abortive And Retractive Initiation R-HSA-74158: RNA Polymerase III Transcription R-HSA-76046: RNA Polymerase III Transcription Initiation R-HSA-76061: RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76066: RNA Polymerase III Transcription Initiation From Type 2 Promoter

> KEGG and Reactome Pathway

[ TOP ]

KEGG

Reactome

R-HSA-74160: Gene Expression
R-HSA-504046: RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
R-HSA-749476: RNA Polymerase III Abortive And Retractive Initiation
R-HSA-74158: RNA Polymerase III Transcription
R-HSA-76046: RNA Polymerase III Transcription Initiation
R-HSA-76061: RNA Polymerase III Transcription Initiation From Type 1 Promoter
R-HSA-76066: RNA Polymerase III Transcription Initiation From Type 2 Promoter

Summary
Symbol	GTF3C1
Name	general transcription factor IIIC subunit 1
Aliases	TFIIIC220; general transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD ); TFIIIC; TFIIICalpha; TF ......
Location	16p12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM4689178	c.4622G>A	p.R1541H	Substitution - Missense	Large_intestine
COSM4391919	c.4736T>C	p.L1579P	Substitution - Missense	Prostate
COSM4689177	c.5339T>C	p.F1780S	Substitution - Missense	Large_intestine
COSM1609127	c.5543A>G	p.E1848G	Substitution - Missense	Liver
COSM702823	c.3972C>T	p.V1324V	Substitution - coding silent	Lung
COSM5675177	c.5620G>T	p.D1874Y	Substitution - Missense	Soft_tissue
COSM969244	c.6068G>A	p.R2023H	Substitution - Missense	Endometrium
COSM1478721	c.3737A>C	p.Y1246S	Substitution - Missense	Breast
COSM4128852	c.227A>T	p.E76V	Substitution - Missense	Thyroid
COSM4689180	c.4454C>T	p.T1485M	Substitution - Missense	Large_intestine
COSM3690702	c.2518G>T	p.G840C	Substitution - Missense	Large_intestine
COSM969250	c.4592G>A	p.R1531Q	Substitution - Missense	Endometrium
COSM4436097	c.4136G>T	p.S1379I	Substitution - Missense	Oesophagus
COSM365074	c.557G>T	p.R186L	Substitution - Missense	Lung
COSM702821	c.3828C>T	p.C1276C	Substitution - coding silent	Prostate
COSM5681678	c.4861G>T	p.D1621Y	Substitution - Missense	Soft_tissue
COSM215640	c.4387G>A	p.V1463I	Substitution - Missense	Central_nervous_system
COSM4059666	c.344G>A	p.R115H	Substitution - Missense	Stomach
COSM1237794	c.5963G>T	p.R1988L	Substitution - Missense	Thyroid
COSM5384615	c.1340A>G	p.K447R	Substitution - Missense	Skin
COSM1377031	c.2027G>A	p.R676Q	Substitution - Missense	Large_intestine
COSM1180827	c.2299delA	p.S767fs*7	Deletion - Frameshift	Large_intestine
COSM3508231	c.2430C>T	p.L810L	Substitution - coding silent	Skin
COSM4565409	c.2084_2085CC>TT	p.S695F	Substitution - Missense	Skin
COSM5447173	c.3277A>G	p.M1093V	Substitution - Missense	Large_intestine
COSM71001	c.433T>G	p.W145G	Substitution - Missense	Ovary
COSM5497269	c.1025A>G	p.N342S	Substitution - Missense	Biliary_tract
COSM3108863	c.3998A>G	p.Y1333C	Substitution - Missense	Upper_aerodigestive_tract
COSM356814	c.544G>A	p.E182K	Substitution - Missense	Lung
COSM471556	c.1068A>G	p.T356T	Substitution - coding silent	Kidney
COSM3508210	c.4958C>T	p.S1653F	Substitution - Missense	Skin
COSM302342	c.4978C>A	p.R1660S	Substitution - Missense	Central_nervous_system
COSM392741	c.2672delC	p.P891fs*44	Deletion - Frameshift	Lung
COSM5499252	c.5472C>T	p.D1824D	Substitution - coding silent	Biliary_tract
COSM4689187	c.438delG	p.K147fs*3	Deletion - Frameshift	Large_intestine
COSM4853467	c.5542G>A	p.E1848K	Substitution - Missense	Breast
COSM5557688	c.4418A>G	p.K1473R	Substitution - Missense	Prostate
COSM4634065	c.5057C>T	p.A1686V	Substitution - Missense	Large_intestine
COSM1377020	c.4978C>T	p.R1660C	Substitution - Missense	Large_intestine
COSM5088514	c.5541delC	p.E1848fs*33	Deletion - Frameshift	Biliary_tract
COSM4643967	c.4408G>T	p.E1470*	Substitution - Nonsense	Large_intestine
COSM702819	c.2950G>T	p.E984*	Substitution - Nonsense	Lung
COSM386726	c.2437G>A	p.G813R	Substitution - Missense	Lung
COSM4151286	c.2338C>A	p.H780N	Substitution - Missense	Kidney
COSM969260	c.2401C>T	p.R801W	Substitution - Missense	Large_intestine
COSM969271	c.961A>G	p.K321E	Substitution - Missense	Endometrium
COSM5054796	c.620G>T	p.G207V	Substitution - Missense	Stomach
COSM5422993	c.516G>A	p.K172K	Substitution - coding silent	Prostate
COSM1609129	c.3090A>G	p.S1030S	Substitution - coding silent	Liver
COSM5384617	c.863G>A	p.R288K	Substitution - Missense	Skin
COSM3508228	c.2678C>T	p.P893L	Substitution - Missense	Skin
COSM4689186	c.571G>T	p.G191W	Substitution - Missense	Large_intestine
COSM4257962	c.897C>T	p.N299N	Substitution - coding silent	Large_intestine
COSM5384614	c.1578C>T	p.H526H	Substitution - coding silent	Skin
COSM702821	c.3828C>T	p.C1276C	Substitution - coding silent	Lung
COSM5659961	c.974-3C>G	p.?	Unknown	Soft_tissue
COSM4824567	c.4801G>A	p.E1601K	Substitution - Missense	Cervix
COSM266646	c.1626_1627delAG	p.R542fs*35	Deletion - Frameshift	Large_intestine
COSM3948416	c.4686C>T	p.D1562D	Substitution - coding silent	Ovary
COSM471553	c.2886T>G	p.I962M	Substitution - Missense	Kidney
COSM266645	c.3129C>T	p.C1043C	Substitution - coding silent	Stomach
COSM1323612	c.3152-2A>T	p.?	Unknown	Ovary
COSM5520918	c.1838G>T	p.R613L	Substitution - Missense	Biliary_tract
COSM4438356	c.5697C>A	p.P1899P	Substitution - coding silent	Oesophagus
COSM3508213	c.4621C>T	p.R1541C	Substitution - Missense	Stomach
COSM1323613	c.4274_4289del16	p.H1425fs*3	Deletion - Frameshift	Ovary
COSM5548462	c.3566C>T	p.A1189V	Substitution - Missense	Prostate
COSM1239039	c.5489A>G	p.E1830G	Substitution - Missense	Oesophagus
COSM5619923	c.4474C>T	p.R1492W	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3108932	c.1395G>A	p.S465S	Substitution - coding silent	Liver
COSM3108890	c.3220_3221ins18	p.S1073_L1074insRDEEGS	Insertion - In frame	Large_intestine
COSM4438690	c.2563G>A	p.E855K	Substitution - Missense	Oesophagus
COSM5760888	c.4058G>A	p.R1353Q	Substitution - Missense	Pancreas
COSM969273	c.761A>G	p.K254R	Substitution - Missense	Endometrium
COSM4128851	c.232A>G	p.I78V	Substitution - Missense	Thyroid
COSM3108847	c.4862A>G	p.D1621G	Substitution - Missense	Large_intestine
COSM4424863	c.1356C>G	p.L452L	Substitution - coding silent	Oesophagus
COSM368626	c.6279G>T	p.L2093L	Substitution - coding silent	Lung
COSM3508217	c.3944C>T	p.S1315F	Substitution - Missense	Skin
COSM4818367	c.2878C>T	p.R960C	Substitution - Missense	Cervix
COSM1377034	c.1092C>T	p.F364F	Substitution - coding silent	Oesophagus
COSM4578877	c.180_190del11	p.Y60fs*1	Deletion - Frameshift	Bone
COSM4689183	c.3613C>T	p.R1205*	Substitution - Nonsense	Large_intestine
COSM3402225	c.3535G>C	p.G1179R	Substitution - Missense	Central_nervous_system
COSM4578875	c.5537C>T	p.P1846L	Substitution - Missense	Bone
COSM1678956	c.5182C>T	p.Q1728*	Substitution - Nonsense	Skin
COSM969261	c.2131C>T	p.R711C	Substitution - Missense	Endometrium
COSM4527139	c.1443G>A	p.E481E	Substitution - coding silent	Skin
COSM969248	c.4869C>T	p.D1623D	Substitution - coding silent	Stomach
COSM1377033	c.1547C>G	p.T516S	Substitution - Missense	Large_intestine
COSM3108916	c.2392C>T	p.P798S	Substitution - Missense	Skin
COSM355063	c.4999A>T	p.S1667C	Substitution - Missense	Lung
COSM1253882	c.625C>G	p.L209V	Substitution - Missense	Oesophagus
COSM4059648	c.3727A>G	p.R1243G	Substitution - Missense	Stomach
COSM4059653	c.3348C>T	p.A1116A	Substitution - coding silent	Stomach
COSM4940524	c.4280T>C	p.L1427P	Substitution - Missense	Liver
COSM3108941	c.1119C>T	p.Y373Y	Substitution - coding silent	Soft_tissue
COSM969245	c.5708A>C	p.D1903A	Substitution - Missense	Endometrium
COSM5728382	c.3779G>A	p.R1260Q	Substitution - Missense	Skin
COSM4926846	c.5900A>G	p.N1967S	Substitution - Missense	Liver
COSM3711992	c.48C>T	p.L16L	Substitution - coding silent	Upper_aerodigestive_tract
COSM4770348	c.2923A>T	p.M975L	Substitution - Missense	Adrenal_gland
COSM5363485	c.982G>A	p.V328I	Substitution - Missense	Large_intestine
COSM5028113	c.4045G>T	p.D1349Y	Substitution - Missense	Breast
COSM3508218	c.3923C>T	p.S1308F	Substitution - Missense	Skin
COSM5933449	c.609-7C>T	p.?	Unknown	Skin
COSM266645	c.3129C>T	p.C1043C	Substitution - coding silent	Stomach
COSM5681680	c.3351_3357delAGGGCTC	p.G1118fs*35	Deletion - Frameshift	Soft_tissue
COSM3508229	c.2625G>A	p.T875T	Substitution - coding silent	Skin
COSM5601590	c.991C>T	p.R331W	Substitution - Missense	Skin
COSM1180827	c.2299delA	p.S767fs*7	Deletion - Frameshift	Large_intestine
COSM4059650	c.3555C>T	p.S1185S	Substitution - coding silent	Stomach
COSM1301787	c.849+1G>T	p.?	Unknown	Urinary_tract
COSM5980946	c.1383G>T	p.M461I	Substitution - Missense	Upper_aerodigestive_tract
COSM471552	c.3722G>T	p.S1241I	Substitution - Missense	Kidney
COSM3948417	c.2911A>T	p.R971W	Substitution - Missense	Ovary
COSM5988076	c.1712C>T	p.A571V	Substitution - Missense	Salivary_gland
COSM969251	c.4015G>A	p.E1339K	Substitution - Missense	Endometrium
COSM4689175	c.6165A>G	p.P2055P	Substitution - coding silent	Large_intestine
COSM4456730	c.101C>T	p.P34L	Substitution - Missense	Skin
COSM4617649	c.285G>T	p.E95D	Substitution - Missense	Large_intestine
COSM1253879	c.5918G>A	p.R1973Q	Substitution - Missense	Oesophagus
COSM1162177	c.1346G>A	p.R449H	Substitution - Missense	Pancreas
COSM1470853	c.5807G>T	p.S1936I	Substitution - Missense	Prostate
COSM4950105	c.713A>T	p.H238L	Substitution - Missense	Liver
COSM4059658	c.1907+1G>A	p.?	Unknown	Stomach
COSM5740589	c.6193G>A	p.V2065M	Substitution - Missense	Small_intestine
COSM702825	c.4969G>A	p.V1657I	Substitution - Missense	Lung
COSM969260	c.2401C>T	p.R801W	Substitution - Missense	Large_intestine
COSM371775	c.2138_2139GG>TT	p.R713>?	Complex	Lung
COSM969256	c.3151+2T>A	p.?	Unknown	Endometrium
COSM4128850	c.5876T>C	p.F1959S	Substitution - Missense	Thyroid
COSM4059644	c.4611C>T	p.D1537D	Substitution - coding silent	Stomach
COSM4059652	c.3516C>T	p.N1172N	Substitution - coding silent	Stomach
COSM5028112	c.6293C>T	p.P2098L	Substitution - Missense	Breast
COSM4607633	c.2000C>A	p.S667Y	Substitution - Missense	Adrenal_gland
COSM126733	c.3089C>G	p.S1030*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM4440419	c.557G>A	p.R186Q	Substitution - Missense	Large_intestine
COSM702822	c.3849C>A	p.L1283L	Substitution - coding silent	Lung
COSM3957394	c.2231G>T	p.G744V	Substitution - Missense	Lung
COSM4059662	c.931C>T	p.Q311*	Substitution - Nonsense	Stomach
COSM140758	c.5323G>T	p.G1775W	Substitution - Missense	Skin
COSM50972	c.3660G>T	p.L1220L	Substitution - coding silent	Breast
COSM969258	c.2485C>T	p.R829W	Substitution - Missense	Endometrium
COSM366201	c.2659C>G	p.R887G	Substitution - Missense	Lung
COSM1253881	c.2182C>G	p.P728A	Substitution - Missense	Oesophagus
COSM4434756	c.2874G>A	p.K958K	Substitution - coding silent	Oesophagus
COSM3108843	c.4994A>G	p.N1665S	Substitution - Missense	Large_intestine
COSM332682	c.3743A>T	p.D1248V	Substitution - Missense	Lung
COSM4059660	c.976A>G	p.T326A	Substitution - Missense	Stomach
COSM4059657	c.2396G>A	p.R799H	Substitution - Missense	Stomach
COSM84341	c.3804G>A	p.Q1268Q	Substitution - coding silent	Pancreas
COSM3794732	c.753G>A	p.R251R	Substitution - coding silent	Urinary_tract
COSM344423	c.248G>T	p.G83V	Substitution - Missense	Lung
COSM184380	c.3733C>T	p.R1245C	Substitution - Missense	Liver
COSM3937000	c.4480C>G	p.L1494V	Substitution - Missense	Oesophagus
COSM4919688	c.1712C>A	p.A571E	Substitution - Missense	Liver
COSM1644649	c.2778+1G>A	p.?	Unknown	Salivary_gland
COSM3508220	c.3710C>T	p.P1237L	Substitution - Missense	Skin
COSM3888288	c.2668C>T	p.P890S	Substitution - Missense	Skin
COSM5603723	c.3081C>T	p.V1027V	Substitution - coding silent	Skin
COSM3508211	c.4754G>A	p.R1585K	Substitution - Missense	Skin
COSM1478719	c.4424G>T	p.S1475I	Substitution - Missense	Breast
COSM4959347	c.4090G>A	p.A1364T	Substitution - Missense	Liver
COSM5885465	c.5178C>T	p.V1726V	Substitution - coding silent	Urinary_tract
COSM434996	c.2359C>T	p.L787L	Substitution - coding silent	Breast
COSM5606600	c.1566T>G	p.V522V	Substitution - coding silent	Skin
COSM5681679	c.3360_3365delTTCCAG	p.S1121_S1122delSS	Deletion - In frame	Soft_tissue
COSM3108933	c.1366G>A	p.V456M	Substitution - Missense	Large_intestine
COSM213586	c.1509C>G	p.N503K	Substitution - Missense	Breast
COSM4059643	c.4662C>T	p.N1554N	Substitution - coding silent	Stomach
COSM4059665	c.875G>A	p.R292H	Substitution - Missense	Stomach
COSM3817650	c.5924+2T>G	p.?	Unknown	Breast
COSM1709006	c.2843C>T	p.P948L	Substitution - Missense	Skin
COSM4059664	c.892C>G	p.L298V	Substitution - Missense	Stomach
COSM3988372	c.498G>A	p.E166E	Substitution - coding silent	Kidney
COSM1478725	c.287A>T	p.D96V	Substitution - Missense	Breast
COSM3508222	c.3700+2T>C	p.?	Unknown	Skin
COSM3948417	c.2911A>T	p.R971W	Substitution - Missense	Ovary
COSM4689181	c.4395G>A	p.V1465V	Substitution - coding silent	Large_intestine
COSM6002295	c.5640G>A	p.M1880I	Substitution - Missense	Prostate
COSM5701608	c.5324_5325GG>TT	p.G1775V	Substitution - Missense	Soft_tissue
COSM3794733	c.276G>C	p.V92V	Substitution - coding silent	Urinary_tract
COSM4828824	c.403C>T	p.R135C	Substitution - Missense	Cervix
COSM271656	c.5588G>A	p.R1863H	Substitution - Missense	Cervix
COSM356446	c.488T>A	p.I163K	Substitution - Missense	Lung
COSM4059651	c.3541G>A	p.A1181T	Substitution - Missense	Stomach
COSM4689179	c.4536G>A	p.T1512T	Substitution - coding silent	Large_intestine
COSM3741867	c.4336T>A	p.S1446T	Substitution - Missense	Liver
COSM4531809	c.1828G>A	p.E610K	Substitution - Missense	Skin
COSM361841	c.2165G>T	p.R722M	Substitution - Missense	Lung
COSM5606600	c.1566T>G	p.V522V	Substitution - coding silent	Skin
COSM3108902	c.2827C>T	p.L943L	Substitution - coding silent	Large_intestine
COSM702815	c.1303G>T	p.E435*	Substitution - Nonsense	Lung
COSM5717849	c.6085C>T	p.L2029L	Substitution - coding silent	Skin
COSM1323611	c.453C>T	p.I151I	Substitution - coding silent	Ovary
COSM5425079	c.143G>T	p.W48L	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM311682	c.4586G>A	p.R1529K	Substitution - Missense	Lung
COSM3108936	c.1289C>T	p.S430F	Substitution - Missense	Skin
COSM3817655	c.1908-1G>T	p.?	Unknown	Breast
COSM4543695	c.3429G>A	p.K1143K	Substitution - coding silent	Skin
COSM1129004	c.3418C>A	p.Q1140K	Substitution - Missense	Prostate
COSM969266	c.1178T>C	p.M393T	Substitution - Missense	Endometrium
COSM1209173	c.4993A>G	p.N1665D	Substitution - Missense	Large_intestine
COSM4059656	c.2516C>T	p.A839V	Substitution - Missense	Stomach
COSM4059667	c.11T>C	p.L4P	Substitution - Missense	Stomach
COSM4442007	c.5293C>T	p.R1765W	Substitution - Missense	Large_intestine
COSM266645	c.3129C>T	p.C1043C	Substitution - coding silent	Large_intestine
COSM1563161	c.2048G>A	p.G683D	Substitution - Missense	Liver
COSM3508238	c.295C>T	p.P99S	Substitution - Missense	Skin
COSM3108950	c.925C>T	p.R309C	Substitution - Missense	Skin
COSM4956155	c.3682A>C	p.I1228L	Substitution - Missense	Liver
COSM4959347	c.4090G>A	p.A1364T	Substitution - Missense	Large_intestine
COSM3508236	c.606C>T	p.F202F	Substitution - coding silent	Skin
COSM1749520	c.4286T>A	p.L1429H	Substitution - Missense	Urinary_tract
COSM4059641	c.5282A>C	p.E1761A	Substitution - Missense	Stomach
COSM220994	c.1214G>A	p.R405Q	Substitution - Missense	Endometrium
COSM3402226	c.1294G>A	p.V432M	Substitution - Missense	Biliary_tract
COSM1377018	c.5619C>T	p.T1873T	Substitution - coding silent	Stomach
COSM184380	c.3733C>T	p.R1245C	Substitution - Missense	Liver
COSM1377035	c.1021C>T	p.R341W	Substitution - Missense	Large_intestine
COSM3672210	c.5918G>T	p.R1973L	Substitution - Missense	Prostate
COSM3787125	c.5957C>T	p.P1986L	Substitution - Missense	Pancreas
COSM1377034	c.1092C>T	p.F364F	Substitution - coding silent	Skin
COSM1609129	c.3090A>G	p.S1030S	Substitution - coding silent	Liver
COSM5670348	c.1768A>C	p.K590Q	Substitution - Missense	Soft_tissue
COSM3817651	c.5230G>C	p.E1744Q	Substitution - Missense	Breast
COSM3948417	c.2911A>T	p.R971W	Substitution - Missense	Ovary
COSM3508212	c.4674C>T	p.A1558A	Substitution - coding silent	Skin
COSM4751665	c.2962G>C	p.D988H	Substitution - Missense	Stomach
COSM3508225	c.2891C>T	p.S964L	Substitution - Missense	Skin
COSM1629853	c.670A>G	p.M224V	Substitution - Missense	Liver
COSM3817654	c.2018G>A	p.R673Q	Substitution - Missense	Breast
COSM4059635	c.6120C>A	p.G2040G	Substitution - coding silent	Stomach
COSM3508206	c.5729C>T	p.P1910L	Substitution - Missense	Skin
COSM969262	c.1885C>T	p.R629C	Substitution - Missense	Endometrium
COSM2151704	c.4408G>C	p.E1470Q	Substitution - Missense	Central_nervous_system
COSM184380	c.3733C>T	p.R1245C	Substitution - Missense	Large_intestine
COSM4059639	c.5566A>G	p.S1856G	Substitution - Missense	Stomach
COSM4950105	c.713A>T	p.H238L	Substitution - Missense	Liver
COSM4647903	c.4907A>G	p.K1636R	Substitution - Missense	Large_intestine
COSM380405	c.663G>T	p.L221L	Substitution - coding silent	Lung
COSM215640	c.4387G>A	p.V1463I	Substitution - Missense	Central_nervous_system
COSM969272	c.820G>T	p.E274*	Substitution - Nonsense	Endometrium
COSM4909684	c.609-2A>T	p.?	Unknown	Liver
COSM5606600	c.1566T>G	p.V522V	Substitution - coding silent	Skin
COSM3888287	c.2712C>T	p.L904L	Substitution - coding silent	Skin
COSM4689184	c.2479A>G	p.S827G	Substitution - Missense	Large_intestine
COSM1377034	c.1092C>T	p.F364F	Substitution - coding silent	Large_intestine
COSM4959347	c.4090G>A	p.A1364T	Substitution - Missense	Liver
COSM5606600	c.1566T>G	p.V522V	Substitution - coding silent	Skin
COSM969265	c.1248C>A	p.F416L	Substitution - Missense	Endometrium
COSM3508227	c.2795A>T	p.E932V	Substitution - Missense	Skin
COSM3772177	c.3808G>A	p.D1270N	Substitution - Missense	Pancreas
COSM4440419	c.557G>A	p.R186Q	Substitution - Missense	Thyroid
COSM3690702	c.2518G>T	p.G840C	Substitution - Missense	Large_intestine
COSM1377018	c.5619C>T	p.T1873T	Substitution - coding silent	Large_intestine
COSM3108936	c.1289C>T	p.S430F	Substitution - Missense	Skin
COSM471555	c.2237G>A	p.S746N	Substitution - Missense	Kidney
COSM3108878	c.3563G>T	p.C1188F	Substitution - Missense	Soft_tissue
COSM1609129	c.3090A>G	p.S1030S	Substitution - coding silent	Liver
COSM5971737	c.4729C>T	p.L1577L	Substitution - coding silent	Upper_aerodigestive_tract
COSM289690	c.5488G>T	p.E1830*	Substitution - Nonsense	Large_intestine
COSM1377034	c.1092C>T	p.F364F	Substitution - coding silent	Large_intestine
COSM4185714	c.5602A>G	p.S1868G	Substitution - Missense	Salivary_gland
COSM4548230	c.4422G>A	p.R1474R	Substitution - coding silent	Skin
COSM2151704	c.4408G>C	p.E1470Q	Substitution - Missense	Central_nervous_system
COSM220994	c.1214G>A	p.R405Q	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM969253	c.3785G>A	p.R1262H	Substitution - Missense	Endometrium
COSM5646271	c.5025G>A	p.M1675I	Substitution - Missense	Oesophagus
COSM969257	c.2949G>T	p.T983T	Substitution - coding silent	Endometrium
COSM1377032	c.1907C>T	p.T636M	Substitution - Missense	Large_intestine
COSM240057	c.5341G>A	p.A1781T	Substitution - Missense	Prostate
COSM4059663	c.901G>A	p.G301R	Substitution - Missense	Stomach
COSM4751669	c.1353G>C	p.E451D	Substitution - Missense	Stomach
COSM271656	c.5588G>A	p.R1863H	Substitution - Missense	Large_intestine
COSM1478723	c.1717A>T	p.S573C	Substitution - Missense	Breast
COSM3988370	c.6100G>A	p.V2034M	Substitution - Missense	Kidney
COSM5454437	c.608+7G>T	p.?	Unknown	Large_intestine
COSM3508215	c.4300C>T	p.Q1434*	Substitution - Nonsense	Skin
COSM557298	c.1743C>T	p.I581I	Substitution - coding silent	Large_intestine
COSM5661482	c.3561C>A	p.L1187L	Substitution - coding silent	Soft_tissue
COSM234781	c.4536G>C	p.T1512T	Substitution - coding silent	Skin
COSM266645	c.3129C>T	p.C1043C	Substitution - coding silent	Large_intestine
COSM3721997	c.5276A>G	p.K1759R	Substitution - Missense	Upper_aerodigestive_tract
COSM3508233	c.1193T>A	p.L398Q	Substitution - Missense	Skin
COSM3108934	c.1350C>T	p.S450S	Substitution - coding silent	Large_intestine
COSM4853467	c.5542G>A	p.E1848K	Substitution - Missense	Upper_aerodigestive_tract
COSM5475853	c.477C>G	p.Y159*	Substitution - Nonsense	Large_intestine
COSM1193772	c.5930G>T	p.C1977F	Substitution - Missense	Lung
COSM1377031	c.2027G>A	p.R676Q	Substitution - Missense	Large_intestine
COSM5054793	c.5686A>G	p.S1896G	Substitution - Missense	Stomach
COSM5690277	c.1471G>T	p.G491C	Substitution - Missense	Soft_tissue
COSM1209174	c.5765C>T	p.A1922V	Substitution - Missense	Urinary_tract
COSM3957393	c.4574A>G	p.Q1525R	Substitution - Missense	Lung
COSM365689	c.5353C>T	p.Q1785*	Substitution - Nonsense	Lung
COSM4853467	c.5542G>A	p.E1848K	Substitution - Missense	Cervix
COSM4890483	c.523G>T	p.D175Y	Substitution - Missense	Upper_aerodigestive_tract
COSM3508226	c.2833C>T	p.R945C	Substitution - Missense	Skin
COSM1609128	c.3429+7G>A	p.?	Unknown	Liver
COSM5384609	c.5739C>T	p.P1913P	Substitution - coding silent	Skin
COSM347423	c.1621G>A	p.E541K	Substitution - Missense	Lung
COSM5363485	c.982G>A	p.V328I	Substitution - Missense	Large_intestine
COSM3988371	c.1193T>C	p.L398P	Substitution - Missense	Kidney
COSM1709005	c.3070C>T	p.R1024C	Substitution - Missense	Skin
COSM123512	c.2984T>A	p.F995Y	Substitution - Missense	Upper_aerodigestive_tract
COSM969252	c.3901T>C	p.L1301L	Substitution - coding silent	Endometrium
COSM3377750	c.2502G>T	p.Q834H	Substitution - Missense	Pancreas
COSM1749520	c.4286T>A	p.L1429H	Substitution - Missense	Urinary_tract
COSM1709007	c.1394C>T	p.S465L	Substitution - Missense	Skin
COSM5384612	c.2534C>T	p.S845F	Substitution - Missense	Skin
COSM376031	c.3864G>T	p.K1288N	Substitution - Missense	Lung
COSM3817652	c.4905G>A	p.V1635V	Substitution - coding silent	Cervix
COSM3402226	c.1294G>A	p.V432M	Substitution - Missense	Central_nervous_system
COSM294432	c.6276G>A	p.R2092R	Substitution - coding silent	Large_intestine
COSM1678956	c.5182C>T	p.Q1728*	Substitution - Nonsense	Skin
COSM1377037	c.283G>T	p.E95*	Substitution - Nonsense	Large_intestine
COSM3888285	c.5497C>T	p.Q1833*	Substitution - Nonsense	Skin
COSM969249	c.4628C>T	p.S1543F	Substitution - Missense	Endometrium
COSM4059640	c.5474C>T	p.A1825V	Substitution - Missense	Stomach
COSM1209171	c.2395C>T	p.R799C	Substitution - Missense	Large_intestine
COSM3508239	c.253T>G	p.L85V	Substitution - Missense	Skin
COSM3420905	c.1674C>T	p.S558S	Substitution - coding silent	Large_intestine
COSM5088514	c.5541delC	p.E1848fs*33	Deletion - Frameshift	Breast
COSM281583	c.2191C>T	p.P731S	Substitution - Missense	Large_intestine
COSM3817652	c.4905G>A	p.V1635V	Substitution - coding silent	Breast
COSM3794731	c.5749G>A	p.E1917K	Substitution - Missense	Urinary_tract
COSM4601810	c.28G>A	p.E10K	Substitution - Missense	Liver
COSM379604	c.33C>T	p.V11V	Substitution - coding silent	Lung
COSM3888286	c.4837G>A	p.E1613K	Substitution - Missense	Skin
COSM4689176	c.5954G>A	p.R1985Q	Substitution - Missense	Large_intestine
COSM3108883	c.3502A>G	p.S1168G	Substitution - Missense	Large_intestine
COSM3508213	c.4621C>T	p.R1541C	Substitution - Missense	Skin
COSM4059647	c.4162G>A	p.E1388K	Substitution - Missense	Stomach
COSM1709004	c.4142C>T	p.A1381V	Substitution - Missense	Skin
COSM5894610	c.4551C>G	p.S1517R	Substitution - Missense	Skin
COSM1609130	c.1658T>G	p.L553R	Substitution - Missense	Liver
COSM5773841	c.929T>A	p.L310*	Substitution - Nonsense	Breast
COSM5581273	c.4488C>T	p.F1496F	Substitution - coding silent	Skin
COSM3108932	c.1395G>A	p.S465S	Substitution - coding silent	Liver
COSM4932382	c.2235A>G	p.P745P	Substitution - coding silent	Liver
COSM969248	c.4869C>T	p.D1623D	Substitution - coding silent	Endometrium
COSM702817	c.2710C>T	p.L904F	Substitution - Missense	Lung
COSM5882693	c.1387G>A	p.E463K	Substitution - Missense	Upper_aerodigestive_tract
COSM3817653	c.4057C>T	p.R1353*	Substitution - Nonsense	Breast
COSM4428426	c.3382A>G	p.K1128E	Substitution - Missense	Oesophagus
COSM334023	c.3625G>T	p.V1209L	Substitution - Missense	Lung
COSM1209172	c.2197G>T	p.G733W	Substitution - Missense	Large_intestine
COSM4499927	c.5535C>T	p.S1845S	Substitution - coding silent	Skin
COSM215641	c.2719G>A	p.D907N	Substitution - Missense	Central_nervous_system
COSM5384616	c.1336G>A	p.E446K	Substitution - Missense	Skin
COSM3764549	c.3328C>A	p.P1110T	Substitution - Missense	Central_nervous_system
COSM5606600	c.1566T>G	p.V522V	Substitution - coding silent	Skin
COSM5347472	c.2739_2755del17	p.L914fs*70	Deletion - Frameshift	Liver
COSM5693438	c.3908C>T	p.A1303V	Substitution - Missense	Soft_tissue
COSM3729641	c.1000A>G	p.K334E	Substitution - Missense	Stomach
COSM969260	c.2401C>T	p.R801W	Substitution - Missense	Endometrium
COSM4975802	c.5064C>T	p.L1688L	Substitution - coding silent	Oesophagus
COSM3508216	c.4167C>T	p.I1389I	Substitution - coding silent	Skin
COSM3508223	c.3051C>T	p.S1017S	Substitution - coding silent	Skin
COSM1301788	c.87G>C	p.E29D	Substitution - Missense	Urinary_tract
COSM3108811	c.6298G>A	p.E2100K	Substitution - Missense	Cervix
COSM702818	c.2796A>T	p.E932D	Substitution - Missense	Lung
COSM5662388	c.46C>T	p.L16F	Substitution - Missense	Soft_tissue
COSM328665	c.5905T>C	p.S1969P	Substitution - Missense	Liver
COSM5658237	c.4112T>C	p.V1371A	Substitution - Missense	Soft_tissue
COSM969267	c.1168C>T	p.R390*	Substitution - Nonsense	Endometrium
COSM1209174	c.5765C>T	p.A1922V	Substitution - Missense	Large_intestine
COSM3508213	c.4621C>T	p.R1541C	Substitution - Missense	Skin
COSM5069860	c.5541_5542insC	p.E1848fs*22	Insertion - Frameshift	Large_intestine
COSM4689182	c.3751G>A	p.D1251N	Substitution - Missense	Large_intestine
COSM3108905	c.2739C>T	p.P913P	Substitution - coding silent	Large_intestine
COSM1478722	c.3456C>G	p.L1152L	Substitution - coding silent	Breast
COSM702816	c.2132G>T	p.R711L	Substitution - Missense	Lung
COSM4598821	c.1770G>T	p.K590N	Substitution - Missense	Upper_aerodigestive_tract
COSM5689109	c.5327G>A	p.R1776H	Substitution - Missense	Soft_tissue
COSM3690702	c.2518G>T	p.G840C	Substitution - Missense	Large_intestine
COSM107312	c.3709C>T	p.P1237S	Substitution - Missense	Skin
COSM969259	c.2444C>A	p.P815H	Substitution - Missense	Endometrium
COSM4578876	c.3172G>A	p.V1058I	Substitution - Missense	Bone
COSM969264	c.1264C>T	p.R422W	Substitution - Missense	Endometrium
COSM5946679	c.4982A>G	p.N1661S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5430753	c.4575G>T	p.Q1525H	Substitution - Missense	Oesophagus
COSM3726037	c.4353+10G>C	p.?	Unknown	Lung
COSM1301785	c.6124G>A	p.E2042K	Substitution - Missense	Urinary_tract
COSM184380	c.3733C>T	p.R1245C	Substitution - Missense	Stomach
COSM1180827	c.2299delA	p.S767fs*7	Deletion - Frameshift	Large_intestine
COSM3508234	c.1147G>A	p.G383R	Substitution - Missense	Skin
COSM5696035	c.5878A>G	p.T1960A	Substitution - Missense	Soft_tissue
COSM4751661	c.5222C>T	p.A1741V	Substitution - Missense	Stomach
COSM1377017	c.5963G>A	p.R1988H	Substitution - Missense	Large_intestine
COSM4910228	c.3515A>G	p.N1172S	Substitution - Missense	Liver
COSM4689174	c.6178C>T	p.L2060F	Substitution - Missense	Large_intestine
COSM1239038	c.4378A>G	p.K1460E	Substitution - Missense	Oesophagus
COSM5454436	c.3094C>T	p.Q1032*	Substitution - Nonsense	Large_intestine
COSM969263	c.1388A>G	p.E463G	Substitution - Missense	Endometrium
COSM4482916	c.2651C>T	p.S884L	Substitution - Missense	Skin
COSM1493646	c.981C>T	p.D327D	Substitution - coding silent	Kidney
COSM1609130	c.1658T>G	p.L553R	Substitution - Missense	Liver
COSM4059654	c.3306G>T	p.E1102D	Substitution - Missense	Stomach
COSM4541149	c.2950G>A	p.E984K	Substitution - Missense	Skin
COSM234781	c.4536G>C	p.T1512T	Substitution - coding silent	Skin
COSM1377022	c.4489G>A	p.V1497M	Substitution - Missense	Large_intestine
COSM3711992	c.48C>T	p.L16L	Substitution - coding silent	Upper_aerodigestive_tract
COSM4770798	c.4149G>T	p.R1383S	Substitution - Missense	Pleura
COSM3508230	c.2487G>A	p.R829R	Substitution - coding silent	Skin
COSM6002295	c.5640G>A	p.M1880I	Substitution - Missense	Prostate
COSM3508214	c.4380G>A	p.K1460K	Substitution - coding silent	Skin
COSM3108836	c.5163C>T	p.S1721S	Substitution - coding silent	Large_intestine
COSM3508209	c.5054C>T	p.P1685L	Substitution - Missense	Skin
COSM4430851	c.3979C>T	p.P1327S	Substitution - Missense	Oesophagus
COSM3957391	c.6117+1G>T	p.?	Unknown	Lung
COSM969254	c.3530T>G	p.I1177S	Substitution - Missense	Endometrium
COSM3888289	c.103T>C	p.F35L	Substitution - Missense	Skin
COSM6002295	c.5640G>A	p.M1880I	Substitution - Missense	Prostate
COSM3721996	c.2080C>A	p.P694T	Substitution - Missense	Upper_aerodigestive_tract
COSM1236043	c.466G>A	p.A156T	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5384613	c.1752C>T	p.V584V	Substitution - coding silent	Skin
COSM1640439	c.4580delT	p.L1527fs*46	Deletion - Frameshift	Stomach
COSM5054795	c.688C>T	p.R230*	Substitution - Nonsense	Stomach
COSM3508232	c.2186C>T	p.P729L	Substitution - Missense	Skin
COSM1377017	c.5963G>A	p.R1988H	Substitution - Missense	Stomach
COSM4501673	c.5956C>T	p.P1986S	Substitution - Missense	Skin
COSM3508218	c.3923C>T	p.S1308F	Substitution - Missense	Skin
COSM969264	c.1264C>T	p.R422W	Substitution - Missense	Liver
COSM4059646	c.4562C>T	p.T1521M	Substitution - Missense	Stomach
COSM1518572	c.3573G>A	p.W1191*	Substitution - Nonsense	Skin
COSM3508224	c.3040C>T	p.L1014L	Substitution - coding silent	Skin
COSM5882692	c.2462A>G	p.E821G	Substitution - Missense	Breast
COSM6008131	c.4870G>A	p.E1624K	Substitution - Missense	Prostate
COSM5717849	c.6085C>T	p.L2029L	Substitution - coding silent	Skin
COSM1301786	c.1281G>C	p.K427N	Substitution - Missense	Urinary_tract
COSM3957392	c.5816G>T	p.G1939V	Substitution - Missense	Lung
COSM5897927	c.742C>T	p.H248Y	Substitution - Missense	Skin
COSM5642737	c.3204C>T	p.S1068S	Substitution - coding silent	Oesophagus
COSM3508207	c.5493C>T	p.D1831D	Substitution - coding silent	Skin
COSM3764549	c.3328C>A	p.P1110T	Substitution - Missense	Central_nervous_system
COSM3508219	c.3781C>T	p.L1261F	Substitution - Missense	Skin
COSM4059659	c.1213C>T	p.R405*	Substitution - Nonsense	Stomach
COSM1478720	c.4192G>T	p.A1398S	Substitution - Missense	Breast
COSM3508204	c.5785C>T	p.Q1929*	Substitution - Nonsense	Skin
COSM3108905	c.2739C>T	p.P913P	Substitution - coding silent	Large_intestine
COSM4838686	c.1202G>C	p.R401T	Substitution - Missense	Cervix
COSM3936999	c.6052G>A	p.E2018K	Substitution - Missense	Oesophagus
COSM4059649	c.3656G>A	p.R1219Q	Substitution - Missense	Stomach
COSM3948418	c.1618G>T	p.E540*	Substitution - Nonsense	Ovary
COSM5507046	c.3767A>T	p.Q1256L	Substitution - Missense	Biliary_tract
COSM4488667	c.3362C>T	p.S1121F	Substitution - Missense	Skin
COSM969246	c.5697C>T	p.P1899P	Substitution - coding silent	Endometrium
COSM1563161	c.2048G>A	p.G683D	Substitution - Missense	Large_intestine
COSM5983474	c.6228C>A	p.D2076E	Substitution - Missense	Upper_aerodigestive_tract
COSM4465350	c.1379C>T	p.S460F	Substitution - Missense	Skin
COSM1470852	c.2493G>A	p.T831T	Substitution - coding silent	Prostate
COSM1180827	c.2299delA	p.S767fs*7	Deletion - Frameshift	Large_intestine
COSM3108944	c.1011G>T	p.K337N	Substitution - Missense	Large_intestine
COSM4059645	c.4591C>T	p.R1531W	Substitution - Missense	Stomach
COSM360815	c.3763C>T	p.L1255L	Substitution - coding silent	Lung
COSM4059638	c.5587C>T	p.R1863C	Substitution - Missense	Stomach
COSM5611986	c.2429T>A	p.L810H	Substitution - Missense	Adrenal_gland
COSM4920857	c.2427C>T	p.Y809Y	Substitution - coding silent	Liver
COSM1609127	c.5543A>G	p.E1848G	Substitution - Missense	Liver
COSM5384610	c.5586G>A	p.R1862R	Substitution - coding silent	Skin
COSM4956155	c.3682A>C	p.I1228L	Substitution - Missense	Liver
COSM74853	c.2198G>A	p.G733E	Substitution - Missense	Ovary
COSM184380	c.3733C>T	p.R1245C	Substitution - Missense	Liver
COSM4480836	c.245C>G	p.T82S	Substitution - Missense	Skin
COSM394149	c.3556G>T	p.E1186*	Substitution - Nonsense	Lung
COSM4614779	c.185delA	p.E62fs*41	Deletion - Frameshift	Large_intestine
COSM1377029	c.2253_2254delTC	p.Q752fs*6	Deletion - Frameshift	Large_intestine
COSM4496155	c.4690C>T	p.P1564S	Substitution - Missense	Skin
COSM3508235	c.609G>A	p.K203K	Substitution - coding silent	Skin
COSM434995	c.5000_5009del10	p.S1667fs*6	Deletion - Frameshift	Breast
COSM3508237	c.309C>T	p.I103I	Substitution - coding silent	Skin
COSM4976891	c.3150A>T	p.L1050L	Substitution - coding silent	Oesophagus
COSM5601590	c.991C>T	p.R331W	Substitution - Missense	Skin
COSM377492	c.2132G>A	p.R711H	Substitution - Missense	Lung
COSM1640440	c.767A>G	p.D256G	Substitution - Missense	Stomach
COSM3108917	c.2348T>C	p.V783A	Substitution - Missense	Large_intestine
COSM3729641	c.1000A>G	p.K334E	Substitution - Missense	Large_intestine
COSM5635105	c.26A>G	p.D9G	Substitution - Missense	Oesophagus
COSM4823449	c.75G>C	p.W25C	Substitution - Missense	Cervix
COSM4059655	c.3205G>A	p.D1069N	Substitution - Missense	Stomach
COSM969268	c.1093G>A	p.E365K	Substitution - Missense	Endometrium
COSM4634066	c.2484A>G	p.E828E	Substitution - coding silent	Large_intestine
COSM969255	c.3314A>G	p.D1105G	Substitution - Missense	Endometrium
COSM3948417	c.2911A>T	p.R971W	Substitution - Missense	Ovary
COSM4059642	c.4914G>A	p.A1638A	Substitution - coding silent	Stomach
COSM1377027	c.3266G>A	p.R1089H	Substitution - Missense	Large_intestine
COSM6002295	c.5640G>A	p.M1880I	Substitution - Missense	Prostate
COSM3508203	c.6014C>T	p.A2005V	Substitution - Missense	Skin
COSM5633312	c.2734C>G	p.L912V	Substitution - Missense	Oesophagus
COSM969243	c.6192C>T	p.P2064P	Substitution - coding silent	Endometrium
COSM4151287	c.1287T>A	p.I429I	Substitution - coding silent	Kidney
COSM4848172	c.1584G>C	p.L528F	Substitution - Missense	Cervix
COSM362763	c.3662A>G	p.K1221R	Substitution - Missense	Lung
COSM5042976	c.1987G>A	p.V663M	Substitution - Missense	Liver
COSM4689185	c.1596G>A	p.P532P	Substitution - coding silent	Large_intestine
COSM4924150	c.6162G>T	p.K2054N	Substitution - Missense	Liver
COSM3361707	c.2794G>A	p.E932K	Substitution - Missense	Kidney
COSM1478724	c.1609G>A	p.G537R	Substitution - Missense	Breast
COSM3108873	c.3655C>T	p.R1219W	Substitution - Missense	Large_intestine
COSM1377017	c.5963G>A	p.R1988H	Substitution - Missense	Breast
COSM3787124	c.6093C>T	p.P2031P	Substitution - coding silent	Pancreas
COSM5717849	c.6085C>T	p.L2029L	Substitution - coding silent	Skin
COSM4185714	c.5602A>G	p.S1868G	Substitution - Missense	Kidney
COSM4544788	c.3641G>T	p.S1214I	Substitution - Missense	Skin
COSM5638897	c.3940C>T	p.H1314Y	Substitution - Missense	Oesophagus
COSM3508205	c.5746C>T	p.L1916F	Substitution - Missense	Skin
COSM4601810	c.28G>A	p.E10K	Substitution - Missense	Upper_aerodigestive_tract
COSM4059637	c.5975G>T	p.G1992V	Substitution - Missense	Stomach
COSM371776	c.2127G>T	p.Q709H	Substitution - Missense	Lung
COSM1253880	c.4197-1G>A	p.?	Unknown	Oesophagus
COSM4059636	c.6074A>G	p.Y2025C	Substitution - Missense	Stomach
COSM3377853	c.2519G>A	p.G840D	Substitution - Missense	Pancreas
COSM3108878	c.3563G>T	p.C1188F	Substitution - Missense	Central_nervous_system
COSM139005	c.2166-1G>A	p.?	Unknown	Skin

> Text Mining based Variations [ TOP ]
There is no record for GTF3C1.

Summary
Symbol	GTF3C1
Name	general transcription factor IIIC subunit 1
Aliases	TFIIIC220; general transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD ); TFIIIC; TFIIICalpha; TF ......
Location	16p12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

[ TOP ]

Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant
Q12789	739	S	Phosphoserine	-	No	None detected
Q12789	1062	S	Phosphoserine	-	No	None detected
Q12789	1068	S	Phosphoserine	-	No	None detected
Q12789	1253	S	Phosphoserine	-	No	None detected
Q12789	1611	S	Phosphoserine	-	No	None detected
Q12789	1632	S	Phosphoserine	-	No	None detected
Q12789	1653	S	Phosphoserine	-	No	None detected
Q12789	1856	S	Phosphoserine	-	Yes	p.S1856G (cancer: STAD)
Q12789	1865	S	Phosphoserine	-	No	None detected
Q12789	1868	S	Phosphoserine	-	No	None detected
Q12789	1896	S	Phosphoserine	-	No	None detected
Q12789	1911	S	Phosphoserine	-	No	None detected
Q12789	1969	S	Phosphoserine	-	No	None detected

Summary
Symbol	GTF3C1
Name	general transcription factor IIIC subunit 1
Aliases	TFIIIC220; general transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD ); TFIIIC; TFIIICalpha; TF ......
Location	16p12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	6.801	6.791	-0.084	0.501	NS
BRCA	Breast invasive carcinoma	112	1100	6.424	7.291	0.899	6.65e-59	Over
CESC	Cervical and endocervical cancers	3	306	6.864	6.797	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	6.48	6.51	0.08	0.342	NS
ESCA	Esophageal carcinoma	11	185	7.081	7.168	-0.221	0.299	NS
GBM	Glioblastoma multiforme	5	166	7.604	6.848	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	7.502	7.106	-0.376	1.3e-05	NS
KIRC	Kidney renal clear cell carcinoma	72	534	6.796	6.445	-0.332	1.07e-11	NS
KIRP	Kidney renal papillary cell carcinoma	32	291	6.922	6.966	0.04	0.631	NS
LAML	Acute Myeloid Leukemia	0	173	NA	6.922	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	7.336	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	5.526	5.61	0.057	0.447	NS
LUAD	Lung adenocarcinoma	59	517	6.636	6.826	0.246	0.000883	NS
LUSC	Lung squamous cell carcinoma	51	501	6.663	6.874	0.296	0.000965	NS
OV	Ovarian serous cystadenocarcinoma	0	307	NA	6.573	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	6.753	6.699	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	7.107	7.062	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	7.869	8.422	0.545	4.08e-13	NS
READ	Rectum adenocarcinoma	10	167	6.459	6.507	0.27	0.103	NS
SARC	Sarcoma	2	263	6.513	7.079	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	6.466	7.373	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	6.764	6.808	-0.137	0.214	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	7.777	NA	NA	NA
THCA	Thyroid carcinoma	59	509	7.632	7.221	-0.35	2.43e-05	NS
THYM	Thymoma	2	120	7.124	7.283	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	6.959	7.075	0.171	0.0394	NS

> Cancer Cell Line Encyclopedia (CCLE)

[ TOP ]

Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	8.7
Autonomic ganglia	CHP212	8.7
Autonomic ganglia	IMR32	9
Autonomic ganglia	KELLY	8.8
Autonomic ganglia	KPNRTBM1	8.7
Autonomic ganglia	KPNSI9S	8.5
Autonomic ganglia	KPNYN	8.7
Autonomic ganglia	MHHNB11	8.6
Autonomic ganglia	NB1	9.2
Autonomic ganglia	NH6	8.5
Autonomic ganglia	SHSY5Y	8.3
Autonomic ganglia	SIMA	8.8
Autonomic ganglia	SKNAS	8.8
Autonomic ganglia	SKNBE2	8.6
Autonomic ganglia	SKNDZ	9
Autonomic ganglia	SKNFI	8.9
Autonomic ganglia	SKNSH	8.1
Biliary tract	HUCCT1	7.6
Biliary tract	HUH28	8.1
Biliary tract	SNU1079	8.4
Biliary tract	SNU1196	8.2
Biliary tract	SNU245	7.8
Biliary tract	SNU308	9.1
Biliary tract	SNU478	8
Bone	143B	8.4
Bone	A673	8.7
Bone	CADOES1	8.4
Bone	CAL78	8.2
Bone	G292CLONEA141B1	8.6
Bone	HOS	8.6
Bone	HS706T	8
Bone	HS737T	8.4
Bone	HS819T	8.1
Bone	HS821T	8.2
Bone	HS822T	8.1
Bone	HS863T	8
Bone	HS870T	7.4
Bone	HS888T	8.6
Bone	MG63	8.9
Bone	MHHES1	8.3
Bone	OUMS27	8.7
Bone	RDES	9.1
Bone	SJSA1	8.8
Bone	SKES1	8.2
Bone	SKNMC	8.8
Bone	SW1353	8.5
Bone	T173	8
Bone	TC71	8.3
Bone	U2OS	8.5
Breast	AU565	8.8
Breast	BT20	8.4
Breast	BT474	8.4
Breast	BT483	8.8
Breast	BT549	8.8
Breast	CAL120	7.6
Breast	CAL148	10.8
Breast	CAL51	8.5
Breast	CAL851	7.8
Breast	CAMA1	8.7
Breast	DU4475	8.5
Breast	EFM192A	8.6
Breast	EFM19	8.6
Breast	EVSAT	9.7
Breast	HCC1143	9.2
Breast	HCC1187	8.7
Breast	HCC1395	9.1
Breast	HCC1419	9.5
Breast	HCC1428	8.8
Breast	HCC1500	8.4
Breast	HCC1569	8.7
Breast	HCC1599	7.2
Breast	HCC1806	7.9
Breast	HCC1937	8.1
Breast	HCC1954	8.1
Breast	HCC202	10.5
Breast	HCC2157	7.9
Breast	HCC2218	8.2
Breast	HCC38	8.4
Breast	HCC70	8.6
Breast	HDQP1	7.4
Breast	HMC18	8.7
Breast	HS274T	8.2
Breast	HS281T	8.3
Breast	HS343T	8.2
Breast	HS578T	8.4
Breast	HS606T	8.1
Breast	HS739T	8.3
Breast	HS742T	7.8
Breast	JIMT1	8.4
Breast	KPL1	8.5
Breast	MCF7	8.4
Breast	MDAMB134VI	7.8
Breast	MDAMB157	7.9
Breast	MDAMB175VII	8.3
Breast	MDAMB231	8
Breast	MDAMB361	9.4
Breast	MDAMB415	8.6
Breast	MDAMB436	9.3
Breast	MDAMB453	9.4
Breast	MDAMB468	7.6
Breast	SKBR3	8.5
Breast	T47D	8.6
Breast	UACC812	9.5
Breast	UACC893	7.5
Breast	YMB1	8.8
Breast	ZR751	7.9
Breast	ZR7530	8.6
Central nervous system	1321N1	8.2
Central nervous system	42MGBA	8.3
Central nervous system	8MGBA	7.9
Central nervous system	A172	8.9
Central nervous system	AM38	8.1
Central nervous system	BECKER	8.8
Central nervous system	CAS1	8.8
Central nervous system	CCFSTTG1	8.7
Central nervous system	D283MED	9.2
Central nervous system	D341MED	8.7
Central nervous system	DAOY	7.9
Central nervous system	DBTRG05MG	8.3
Central nervous system	DKMG	7.2
Central nervous system	GAMG	7.9
Central nervous system	GB1	9
Central nervous system	GI1	8.5
Central nervous system	GMS10	8.2
Central nervous system	GOS3	7.9
Central nervous system	H4	8.5
Central nervous system	HS683	8.6
Central nervous system	KALS1	8.3
Central nervous system	KG1C	8.2
Central nervous system	KNS42	8.8
Central nervous system	KNS60	8.1
Central nervous system	KNS81	8.2
Central nervous system	KS1	8.7
Central nervous system	LN18	10.2
Central nervous system	LN229	8.1
Central nervous system	M059K	8.8
Central nervous system	MOGGCCM	8.4
Central nervous system	MOGGUVW	8.6
Central nervous system	NMCG1	8.4
Central nervous system	ONS76	8.8
Central nervous system	SF126	8.5
Central nervous system	SF295	9.2
Central nervous system	SNB19	8.1
Central nervous system	SNU1105	8.4
Central nervous system	SNU201	9.1
Central nervous system	SNU466	8.7
Central nervous system	SNU489	8.8
Central nervous system	SNU626	8.7
Central nervous system	SNU738	8.4
Central nervous system	SW1088	9
Central nervous system	SW1783	8.5
Central nervous system	T98G	8.8
Central nervous system	TM31	8.4
Central nervous system	U118MG	9.3
Central nervous system	U138MG	8.5
Central nervous system	U251MG	8
Central nervous system	U87MG	7.6
Central nervous system	YH13	8.9
Central nervous system	YKG1	8.7
Endometrium	AN3CA	9
Endometrium	COLO684	9.4
Endometrium	EFE184	7.5
Endometrium	EN	9.2
Endometrium	ESS1	8.3
Endometrium	HEC108	8.7
Endometrium	HEC151	8.8
Endometrium	HEC1A	7.8
Endometrium	HEC1B	8.1
Endometrium	HEC251	8.5
Endometrium	HEC265	8.6
Endometrium	HEC50B	8.7
Endometrium	HEC59	8.4
Endometrium	HEC6	7.6
Endometrium	ISHIKAWAHERAKLIO02ER	8.7
Endometrium	JHUEM1	8.9
Endometrium	JHUEM2	9.2
Endometrium	JHUEM3	8.1
Endometrium	KLE	8.5
Endometrium	MFE280	8.5
Endometrium	MFE296	9.3
Endometrium	MFE319	8.3
Endometrium	RL952	8.4
Endometrium	SNGM	8.4
Endometrium	SNU1077	9.3
Endometrium	SNU685	8.4
Endometrium	TEN	8.8
Haematopoietic and lymphoid	697	8.2
Haematopoietic and lymphoid	A3KAW	9
Haematopoietic and lymphoid	A4FUK	8.3
Haematopoietic and lymphoid	ALLSIL	8.5
Haematopoietic and lymphoid	AML193	8.2
Haematopoietic and lymphoid	AMO1	8.3
Haematopoietic and lymphoid	BCP1	8.9
Haematopoietic and lymphoid	BDCM	8.2
Haematopoietic and lymphoid	BL41	8.4
Haematopoietic and lymphoid	BL70	8.3
Haematopoietic and lymphoid	BV173	8.6
Haematopoietic and lymphoid	CA46	8.5
Haematopoietic and lymphoid	CI1	8.5
Haematopoietic and lymphoid	CMK115	8.1
Haematopoietic and lymphoid	CMK86	8.4
Haematopoietic and lymphoid	CMK	8.5
Haematopoietic and lymphoid	CMLT1	8.5
Haematopoietic and lymphoid	COLO775	9.1
Haematopoietic and lymphoid	DAUDI	8.1
Haematopoietic and lymphoid	DB	8.7
Haematopoietic and lymphoid	DEL	8
Haematopoietic and lymphoid	DND41	8.7
Haematopoietic and lymphoid	DOHH2	8.2
Haematopoietic and lymphoid	EB1	8.2
Haematopoietic and lymphoid	EB2	7.9
Haematopoietic and lymphoid	EHEB	8.2
Haematopoietic and lymphoid	EJM	8.7
Haematopoietic and lymphoid	EM2	8.2
Haematopoietic and lymphoid	EOL1	8
Haematopoietic and lymphoid	F36P	7.8
Haematopoietic and lymphoid	GA10	8
Haematopoietic and lymphoid	GDM1	8.1
Haematopoietic and lymphoid	GRANTA519	7.8
Haematopoietic and lymphoid	HDLM2	7.2
Haematopoietic and lymphoid	HDMYZ	8.2
Haematopoietic and lymphoid	HEL9217	8.2
Haematopoietic and lymphoid	HEL	7.7
Haematopoietic and lymphoid	HH	8.6
Haematopoietic and lymphoid	HL60	8.6
Haematopoietic and lymphoid	HPBALL	9.6
Haematopoietic and lymphoid	HS604T	8.1
Haematopoietic and lymphoid	HS611T	8.2
Haematopoietic and lymphoid	HS616T	8.4
Haematopoietic and lymphoid	HS751T	7.7
Haematopoietic and lymphoid	HT	8.4
Haematopoietic and lymphoid	HTK	8.3
Haematopoietic and lymphoid	HUNS1	8.1
Haematopoietic and lymphoid	HUT102	8.4
Haematopoietic and lymphoid	HUT78	8.4
Haematopoietic and lymphoid	JEKO1	9
Haematopoietic and lymphoid	JK1	7.9
Haematopoietic and lymphoid	JM1	8.4
Haematopoietic and lymphoid	JURKAT	8.3
Haematopoietic and lymphoid	JURLMK1	8.3
Haematopoietic and lymphoid	JVM2	8.7
Haematopoietic and lymphoid	JVM3	7.9
Haematopoietic and lymphoid	K562	8.1
Haematopoietic and lymphoid	KARPAS299	8.5
Haematopoietic and lymphoid	KARPAS422	8.3
Haematopoietic and lymphoid	KARPAS620	8.5
Haematopoietic and lymphoid	KASUMI1	6.7
Haematopoietic and lymphoid	KASUMI2	8.4
Haematopoietic and lymphoid	KASUMI6	7.9
Haematopoietic and lymphoid	KCL22	8.3
Haematopoietic and lymphoid	KE37	8.3
Haematopoietic and lymphoid	KE97	7.8
Haematopoietic and lymphoid	KG1	8.1
Haematopoietic and lymphoid	KHM1B	8.5
Haematopoietic and lymphoid	KIJK	8.1
Haematopoietic and lymphoid	KMH2	8.6
Haematopoietic and lymphoid	KMM1	8.8
Haematopoietic and lymphoid	KMS11	8.9
Haematopoietic and lymphoid	KMS12BM	8.6
Haematopoietic and lymphoid	KMS18	8.3
Haematopoietic and lymphoid	KMS20	8.6
Haematopoietic and lymphoid	KMS21BM	7.7
Haematopoietic and lymphoid	KMS26	8.8
Haematopoietic and lymphoid	KMS27	8
Haematopoietic and lymphoid	KMS28BM	8.5
Haematopoietic and lymphoid	KMS34	8.2
Haematopoietic and lymphoid	KO52	8
Haematopoietic and lymphoid	KOPN8	8.8
Haematopoietic and lymphoid	KU812	7.8
Haematopoietic and lymphoid	KYO1	8.6
Haematopoietic and lymphoid	L1236	8
Haematopoietic and lymphoid	L363	9
Haematopoietic and lymphoid	L428	8.4
Haematopoietic and lymphoid	L540	8.1
Haematopoietic and lymphoid	LAMA84	8.1
Haematopoietic and lymphoid	LOUCY	8.4
Haematopoietic and lymphoid	LP1	8.7
Haematopoietic and lymphoid	M07E	8.1
Haematopoietic and lymphoid	MC116	7.9
Haematopoietic and lymphoid	ME1	8.6
Haematopoietic and lymphoid	MEC1	7.5
Haematopoietic and lymphoid	MEC2	8.1
Haematopoietic and lymphoid	MEG01	9
Haematopoietic and lymphoid	MHHCALL2	8.1
Haematopoietic and lymphoid	MHHCALL3	8.3
Haematopoietic and lymphoid	MHHCALL4	8.2
Haematopoietic and lymphoid	MINO	8.6
Haematopoietic and lymphoid	MJ	8.6
Haematopoietic and lymphoid	MM1S	8.2
Haematopoietic and lymphoid	MOLM13	7.9
Haematopoietic and lymphoid	MOLM16	7.9
Haematopoietic and lymphoid	MOLM6	8.1
Haematopoietic and lymphoid	MOLP2	8.1
Haematopoietic and lymphoid	MOLP8	8.4
Haematopoietic and lymphoid	MOLT13	8.6
Haematopoietic and lymphoid	MOLT16	8.2
Haematopoietic and lymphoid	MOLT4	8
Haematopoietic and lymphoid	MONOMAC1	8.3
Haematopoietic and lymphoid	MONOMAC6	8.5
Haematopoietic and lymphoid	MOTN1	8.6
Haematopoietic and lymphoid	MUTZ5	8.3
Haematopoietic and lymphoid	MV411	8.4
Haematopoietic and lymphoid	NALM19	8.4
Haematopoietic and lymphoid	NALM1	8.1
Haematopoietic and lymphoid	NALM6	8.6
Haematopoietic and lymphoid	NAMALWA	8.8
Haematopoietic and lymphoid	NB4	8.1
Haematopoietic and lymphoid	NCIH929	7.7
Haematopoietic and lymphoid	NCO2	8.1
Haematopoietic and lymphoid	NOMO1	8.2
Haematopoietic and lymphoid	NUDHL1	8.8
Haematopoietic and lymphoid	NUDUL1	8.7
Haematopoietic and lymphoid	OCIAML2	8
Haematopoietic and lymphoid	OCIAML3	9.6
Haematopoietic and lymphoid	OCIAML5	7.8
Haematopoietic and lymphoid	OCILY10	8.6
Haematopoietic and lymphoid	OCILY19	8.5
Haematopoietic and lymphoid	OCILY3	8.1
Haematopoietic and lymphoid	OCIM1	8.1
Haematopoietic and lymphoid	OPM2	8.5
Haematopoietic and lymphoid	P12ICHIKAWA	8.6
Haematopoietic and lymphoid	P31FUJ	7.5
Haematopoietic and lymphoid	P3HR1	8.2
Haematopoietic and lymphoid	PCM6	8.2
Haematopoietic and lymphoid	PEER	8.6
Haematopoietic and lymphoid	PF382	8.9
Haematopoietic and lymphoid	PFEIFFER	9.5
Haematopoietic and lymphoid	PL21	8.1
Haematopoietic and lymphoid	RAJI	8
Haematopoietic and lymphoid	RCHACV	8.1
Haematopoietic and lymphoid	REC1	8.2
Haematopoietic and lymphoid	REH	8.6
Haematopoietic and lymphoid	RI1	8.9
Haematopoietic and lymphoid	RL	8.1
Haematopoietic and lymphoid	RPMI8226	8.3
Haematopoietic and lymphoid	RPMI8402	8.2
Haematopoietic and lymphoid	RS411	8
Haematopoietic and lymphoid	SEM	7.8
Haematopoietic and lymphoid	SET2	8.4
Haematopoietic and lymphoid	SIGM5	8
Haematopoietic and lymphoid	SKM1	8
Haematopoietic and lymphoid	SKMM2	8.4
Haematopoietic and lymphoid	SR786	8.2
Haematopoietic and lymphoid	ST486	8.2
Haematopoietic and lymphoid	SUDHL10	8.5
Haematopoietic and lymphoid	SUDHL1	8.3
Haematopoietic and lymphoid	SUDHL4	8.4
Haematopoietic and lymphoid	SUDHL5	7.9
Haematopoietic and lymphoid	SUDHL6	8.1
Haematopoietic and lymphoid	SUDHL8	8.8
Haematopoietic and lymphoid	SUPB15	8.3
Haematopoietic and lymphoid	SUPHD1	8.6
Haematopoietic and lymphoid	SUPM2	8.1
Haematopoietic and lymphoid	SUPT11	9.2
Haematopoietic and lymphoid	SUPT1	7.9
Haematopoietic and lymphoid	TALL1	8.4
Haematopoietic and lymphoid	TF1	8.6
Haematopoietic and lymphoid	THP1	8.1
Haematopoietic and lymphoid	TO175T	8.4
Haematopoietic and lymphoid	TOLEDO	8.4
Haematopoietic and lymphoid	U266B1	8.3
Haematopoietic and lymphoid	U937	8.7
Haematopoietic and lymphoid	UT7	8.2
Haematopoietic and lymphoid	WSUDLCL2	8.4
Kidney	769P	8.5
Kidney	786O	8.9
Kidney	A498	9
Kidney	A704	7.5
Kidney	ACHN	8.8
Kidney	BFTC909	8.2
Kidney	CAKI1	8.3
Kidney	CAKI2	8.4
Kidney	CAL54	8.8
Kidney	KMRC1	7.9
Kidney	KMRC20	8.6
Kidney	KMRC2	8.4
Kidney	KMRC3	8.2
Kidney	OSRC2	8.4
Kidney	RCC10RGB	8.2
Kidney	SNU1272	8.2
Kidney	SNU349	8
Kidney	TUHR10TKB	7.9
Kidney	TUHR14TKB	8.8
Kidney	TUHR4TKB	8
Kidney	VMRCRCW	8.5
Kidney	VMRCRCZ	8.5
Large intestine	C2BBE1	8.3
Large intestine	CCK81	8
Large intestine	CL11	8.2
Large intestine	CL14	9.2
Large intestine	CL34	8
Large intestine	CL40	8.5
Large intestine	COLO205	8
Large intestine	COLO320	9.4
Large intestine	COLO678	8.2
Large intestine	CW2	9
Large intestine	DLD1	8.4
Large intestine	GP2D	8.5
Large intestine	HCC56	8.4
Large intestine	HCT116	9
Large intestine	HCT15	7.7
Large intestine	HS675T	8.3
Large intestine	HS698T	8.4
Large intestine	HT115	8.2
Large intestine	HT29	8.2
Large intestine	HT55	8.2
Large intestine	KM12	7.5
Large intestine	LOVO	7.9
Large intestine	LS1034	8.2
Large intestine	LS123	8.4
Large intestine	LS180	8
Large intestine	LS411N	7.3
Large intestine	LS513	7.2
Large intestine	MDST8	8.2
Large intestine	NCIH508	8.1
Large intestine	NCIH716	8.4
Large intestine	NCIH747	8.3
Large intestine	OUMS23	9.1
Large intestine	RCM1	7.9
Large intestine	RKO	7.9
Large intestine	SKCO1	8.3
Large intestine	SNU1040	8.1
Large intestine	SNU1197	8.3
Large intestine	SNU175	8.3
Large intestine	SNU283	8.3
Large intestine	SNU407	8.3
Large intestine	SNU503	8.9
Large intestine	SNU61	8.2
Large intestine	SNU81	7.8
Large intestine	SNUC1	7.9
Large intestine	SNUC2A	8.7
Large intestine	SNUC4	8.1
Large intestine	SNUC5	8.4
Large intestine	SW1116	8.2
Large intestine	SW1417	8.3
Large intestine	SW1463	8.1
Large intestine	SW403	8.2
Large intestine	SW480	8.2
Large intestine	SW48	8.1
Large intestine	SW620	8.9
Large intestine	SW837	8.5
Large intestine	SW948	7.6
Large intestine	T84	8.5
Liver	ALEXANDERCELLS	8.1
Liver	C3A	8.7
Liver	HEP3B217	8.1
Liver	HEPG2	8.8
Liver	HLE	8.5
Liver	HLF	8.5
Liver	HUH1	8.4
Liver	HUH6	8.3
Liver	HUH7	8.4
Liver	JHH1	8.4
Liver	JHH2	9
Liver	JHH4	8
Liver	JHH5	8
Liver	JHH6	7.3
Liver	JHH7	8.3
Liver	LI7	7.9
Liver	PLCPRF5	8.5
Liver	SKHEP1	7.4
Liver	SNU182	8.6
Liver	SNU387	8.5
Liver	SNU398	8.5
Liver	SNU423	8.6
Liver	SNU449	8.6
Liver	SNU475	8.3
Liver	SNU761	8.2
Liver	SNU878	7.4
Liver	SNU886	8.5
Lung	A549	9
Lung	ABC1	7.9
Lung	BEN	9.8
Lung	CAL12T	7.8
Lung	CALU1	8.5
Lung	CALU3	8.5
Lung	CALU6	8.4
Lung	CHAGOK1	7.7
Lung	COLO668	7.9
Lung	COLO699	8.7
Lung	CORL105	8.6
Lung	CORL23	8.6
Lung	CORL24	7.6
Lung	CORL279	9.2
Lung	CORL311	8.6
Lung	CORL47	8.6
Lung	CORL51	8.1
Lung	CORL88	8.9
Lung	CORL95	8
Lung	CPCN	9
Lung	DMS114	9.2
Lung	DMS153	8.5
Lung	DMS273	9.4
Lung	DMS454	8.7
Lung	DMS53	8.2
Lung	DMS79	8.6
Lung	DV90	7.8
Lung	EBC1	8.7
Lung	EPLC272H	8
Lung	HARA	8.7
Lung	HCC1171	8
Lung	HCC1195	8.3
Lung	HCC15	8.7
Lung	HCC2279	9.1
Lung	HCC2935	8.7
Lung	HCC33	8.7
Lung	HCC366	8.7
Lung	HCC4006	8.9
Lung	HCC44	7.6
Lung	HCC78	8.9
Lung	HCC827	8.1
Lung	HCC95	8.1
Lung	HLC1	8.3
Lung	HLFA	8.4
Lung	HS229T	8
Lung	HS618T	8.2
Lung	IALM	9.4
Lung	KNS62	8.5
Lung	LC1F	8.6
Lung	LC1SQSF	7.3
Lung	LCLC103H	8.4
Lung	LCLC97TM1	8.5
Lung	LK2	8.7
Lung	LOUNH91	8.4
Lung	LU65	8.4
Lung	LU99	8.1
Lung	LUDLU1	7.5
Lung	LXF289	8.2
Lung	MORCPR	8.2
Lung	NCIH1048	8.1
Lung	NCIH1092	8.6
Lung	NCIH1105	8.7
Lung	NCIH1155	8.4
Lung	NCIH1184	8.2
Lung	NCIH1299	8.7
Lung	NCIH1339	8.9
Lung	NCIH1341	8.6
Lung	NCIH1355	8.5
Lung	NCIH1373	8.4
Lung	NCIH1385	7.9
Lung	NCIH1395	8.9
Lung	NCIH1435	8.5
Lung	NCIH1436	8.6
Lung	NCIH1437	9.1
Lung	NCIH146	9
Lung	NCIH1563	8.9
Lung	NCIH1568	8.1
Lung	NCIH1573	8.5
Lung	NCIH1581	8.4
Lung	NCIH1618	8.7
Lung	NCIH1623	8
Lung	NCIH1648	8.1
Lung	NCIH1650	9.2
Lung	NCIH1651	7.7
Lung	NCIH1666	8.1
Lung	NCIH1693	7.4
Lung	NCIH1694	8.4
Lung	NCIH1703	8.4
Lung	NCIH1734	8
Lung	NCIH1755	8.4
Lung	NCIH1781	7.9
Lung	NCIH1792	8.5
Lung	NCIH1793	8.4
Lung	NCIH1836	8.3
Lung	NCIH1838	8.2
Lung	NCIH1869	8.1
Lung	NCIH1876	8.5
Lung	NCIH1915	7
Lung	NCIH1930	9.2
Lung	NCIH1944	7.2
Lung	NCIH1963	8.4
Lung	NCIH196	8
Lung	NCIH1975	8.6
Lung	NCIH2009	8.4
Lung	NCIH2023	8.5
Lung	NCIH2029	8.4
Lung	NCIH2030	8.6
Lung	NCIH2066	8.9
Lung	NCIH2081	8.2
Lung	NCIH2085	8.1
Lung	NCIH2087	8.5
Lung	NCIH209	8.7
Lung	NCIH2106	9.3
Lung	NCIH2110	7.6
Lung	NCIH211	8.9
Lung	NCIH2122	8
Lung	NCIH2126	7
Lung	NCIH2141	8.9
Lung	NCIH2170	9
Lung	NCIH2171	9.6
Lung	NCIH2172	8.5
Lung	NCIH2196	8.7
Lung	NCIH2227	8.9
Lung	NCIH2228	8
Lung	NCIH226	8.1
Lung	NCIH2286	8.7
Lung	NCIH2291	8.4
Lung	NCIH2342	7
Lung	NCIH2347	7.5
Lung	NCIH23	8.4
Lung	NCIH2405	8.5
Lung	NCIH2444	7.7
Lung	NCIH292	8.5
Lung	NCIH322	7.9
Lung	NCIH3255	8.4
Lung	NCIH358	8.7
Lung	NCIH441	8.9
Lung	NCIH446	8.4
Lung	NCIH460	8.6
Lung	NCIH510	9.3
Lung	NCIH520	9.2
Lung	NCIH522	8.8
Lung	NCIH524	9.5
Lung	NCIH526	8.4
Lung	NCIH596	8.3
Lung	NCIH647	8.3
Lung	NCIH650	7.8
Lung	NCIH661	8.4
Lung	NCIH69	8.9
Lung	NCIH727	8.2
Lung	NCIH810	8.7
Lung	NCIH82	9.5
Lung	NCIH838	7.3
Lung	NCIH841	8.9
Lung	NCIH854	8.9
Lung	NCIH889	8.7
Lung	PC14	8.7
Lung	RERFLCAD1	7.9
Lung	RERFLCAD2	8.2
Lung	RERFLCAI	8.4
Lung	RERFLCKJ	8.6
Lung	RERFLCMS	8.2
Lung	RERFLCSQ1	7.8
Lung	SBC5	8.5
Lung	SCLC21H	8.7
Lung	SHP77	9
Lung	SKLU1	7.9
Lung	SKMES1	7.6
Lung	SQ1	8.3
Lung	SW1271	7.9
Lung	SW1573	8.4
Lung	SW900	8.2
Lung	VMRCLCD	9.1
Lung	VMRCLCP	8.5
Oesophagus	COLO680N	8
Oesophagus	ECGI10	8.1
Oesophagus	KYSE140	8.3
Oesophagus	KYSE150	7.8
Oesophagus	KYSE180	8.8
Oesophagus	KYSE270	9
Oesophagus	KYSE30	8.8
Oesophagus	KYSE410	8.5
Oesophagus	KYSE450	8.1
Oesophagus	KYSE510	8.5
Oesophagus	KYSE520	9
Oesophagus	KYSE70	7.9
Oesophagus	OE19	7.6
Oesophagus	OE33	7.9
Oesophagus	TE10	8.5
Oesophagus	TE11	8
Oesophagus	TE14	8.2
Oesophagus	TE15	8.2
Oesophagus	TE1	8.1
Oesophagus	TE4	9.2
Oesophagus	TE5	8.5
Oesophagus	TE6	8
Oesophagus	TE8	8.6
Oesophagus	TE9	8.6
Oesophagus	TT	8.1
Ovary	59M	8.6
Ovary	A2780	9.2
Ovary	CAOV3	8.7
Ovary	CAOV4	7.9
Ovary	COLO704	8.8
Ovary	COV318	8.4
Ovary	COV362	7.7
Ovary	COV434	8.5
Ovary	COV504	8.8
Ovary	COV644	8.2
Ovary	EFO21	8.4
Ovary	EFO27	8.7
Ovary	ES2	8.6
Ovary	FUOV1	8.9
Ovary	HEYA8	7.6
Ovary	HS571T	8.3
Ovary	IGROV1	8.8
Ovary	JHOC5	8.3
Ovary	JHOM1	9.1
Ovary	JHOM2B	7.7
Ovary	JHOS2	7.6
Ovary	JHOS4	8.1
Ovary	KURAMOCHI	9
Ovary	MCAS	8
Ovary	NIHOVCAR3	8.3
Ovary	OAW28	8.7
Ovary	OAW42	9
Ovary	OC314	8.7
Ovary	OC316	8.6
Ovary	ONCODG1	8.2
Ovary	OV56	8.2
Ovary	OV7	8.8
Ovary	OV90	8.5
Ovary	OVCAR4	9
Ovary	OVCAR8	7.8
Ovary	OVISE	8.4
Ovary	OVK18	9.3
Ovary	OVKATE	7.8
Ovary	OVMANA	8.6
Ovary	OVSAHO	8.2
Ovary	OVTOKO	8.4
Ovary	RMGI	9
Ovary	RMUGS	8.8
Ovary	SKOV3	8.3
Ovary	SNU119	8.4
Ovary	SNU840	8.6
Ovary	SNU8	8.1
Ovary	TOV112D	8.7
Ovary	TOV21G	8.3
Ovary	TYKNU	8
Pancreas	ASPC1	8.1
Pancreas	BXPC3	8.6
Pancreas	CAPAN1	8.5
Pancreas	CAPAN2	8.2
Pancreas	CFPAC1	8.1
Pancreas	DANG	8.1
Pancreas	HPAC	7.9
Pancreas	HPAFII	8.3
Pancreas	HS766T	9.1
Pancreas	HUPT3	8.3
Pancreas	HUPT4	8.3
Pancreas	KCIMOH1	7.1
Pancreas	KLM1	9.1
Pancreas	KP2	8.2
Pancreas	KP3	8
Pancreas	KP4	8.4
Pancreas	L33	8.9
Pancreas	MIAPACA2	9.6
Pancreas	PANC0203	8.4
Pancreas	PANC0213	9.5
Pancreas	PANC0327	7.6
Pancreas	PANC0403	7.9
Pancreas	PANC0504	8.1
Pancreas	PANC0813	8.1
Pancreas	PANC1005	8.6
Pancreas	PANC1	8.7
Pancreas	PATU8902	8
Pancreas	PATU8988S	8
Pancreas	PATU8988T	8.3
Pancreas	PK1	7.8
Pancreas	PK45H	8.1
Pancreas	PK59	7.6
Pancreas	PL45	8.4
Pancreas	PSN1	8.8
Pancreas	QGP1	8.2
Pancreas	SNU213	7.6
Pancreas	SNU324	7.5
Pancreas	SNU410	8.2
Pancreas	SU8686	8.3
Pancreas	SUIT2	8.1
Pancreas	SW1990	7.6
Pancreas	T3M4	8.2
Pancreas	TCCPAN2	8.1
Pancreas	YAPC	8.4
Pleura	ACCMESO1	7.5
Pleura	DM3	8.8
Pleura	ISTMES1	8.7
Pleura	ISTMES2	8.4
Pleura	JL1	9
Pleura	MPP89	7.8
Pleura	MSTO211H	8.3
Pleura	NCIH2052	8.4
Pleura	NCIH2452	8
Pleura	NCIH28	8.6
Prostate	22RV1	8.5
Prostate	DU145	8
Prostate	LNCAPCLONEFGC	8.8
Prostate	MDAPCA2B	9.4
Prostate	NCIH660	7.9
Prostate	PC3	8.3
Prostate	VCAP	8.6
Salivary gland	A253	8
Salivary gland	YD15	8.3
Skin	A101D	8.4
Skin	A2058	8.5
Skin	A375	8.7
Skin	C32	8.5
Skin	CHL1	9.1
Skin	CJM	7.8
Skin	COLO679	8.9
Skin	COLO741	8.3
Skin	COLO783	8.3
Skin	COLO792	8.3
Skin	COLO800	8.6
Skin	COLO818	8.1
Skin	COLO829	9.3
Skin	COLO849	9.5
Skin	G361	8.8
Skin	GRM	9.1
Skin	HMCB	9.3
Skin	HS294T	8.4
Skin	HS600T	8.2
Skin	HS688AT	8.3
Skin	HS695T	8.5
Skin	HS839T	8.1
Skin	HS852T	8.4
Skin	HS895T	7.3
Skin	HS934T	8.1
Skin	HS936T	8.4
Skin	HS939T	8.5
Skin	HS940T	8.5
Skin	HS944T	8.1
Skin	HT144	8.6
Skin	IGR1	8.5
Skin	IGR37	9.4
Skin	IGR39	9.3
Skin	IPC298	8.1
Skin	K029AX	9
Skin	LOXIMVI	7.7
Skin	MALME3M	7.9
Skin	MDAMB435S	7.7
Skin	MELHO	8.7
Skin	MELJUSO	8.7
Skin	MEWO	7.8
Skin	RPMI7951	8.1
Skin	RVH421	8.5
Skin	SH4	8
Skin	SKMEL1	8.8
Skin	SKMEL24	8.5
Skin	SKMEL28	8.7
Skin	SKMEL2	8.6
Skin	SKMEL30	8
Skin	SKMEL31	8.7
Skin	SKMEL3	8.9
Skin	SKMEL5	7.5
Skin	UACC257	8.2
Skin	UACC62	8.7
Skin	WM115	8.6
Skin	WM1799	8.2
Skin	WM2664	8.3
Skin	WM793	8.6
Skin	WM88	8.8
Skin	WM983B	8
Small intestine	HUTU80	9
Soft tissue	A204	8.2
Soft tissue	G401	9.4
Soft tissue	G402	8.5
Soft tissue	GCT	8.4
Soft tissue	HS729	8.5
Soft tissue	HT1080	8.5
Soft tissue	KYM1	8.7
Soft tissue	MESSA	9
Soft tissue	RD	8.9
Soft tissue	RH30	9.7
Soft tissue	RH41	9.6
Soft tissue	RKN	8.2
Soft tissue	S117	8.3
Soft tissue	SJRH30	9.5
Soft tissue	SKLMS1	8.1
Soft tissue	SKUT1	8.6
Soft tissue	TE125T	7.3
Soft tissue	TE159T	8.6
Soft tissue	TE441T	9.1
Soft tissue	TE617T	9
Stomach	2313287	7.5
Stomach	AGS	8.6
Stomach	AZ521	9.1
Stomach	ECC10	8.5
Stomach	ECC12	8.4
Stomach	FU97	9.2
Stomach	GCIY	8.9
Stomach	GSS	8.6
Stomach	GSU	7.7
Stomach	HGC27	8.7
Stomach	HS746T	8.6
Stomach	HUG1N	8
Stomach	IM95	7.5
Stomach	KATOIII	8.4
Stomach	KE39	8.2
Stomach	LMSU	8.2
Stomach	MKN1	8.5
Stomach	MKN45	8.7
Stomach	MKN74	8.5
Stomach	MKN7	8.7
Stomach	NCCSTCK140	8.7
Stomach	NCIN87	9
Stomach	NUGC2	8.8
Stomach	NUGC3	8
Stomach	NUGC4	8.3
Stomach	OCUM1	8.5
Stomach	RERFGC1B	8.7
Stomach	SH10TC	8.6
Stomach	SNU16	7.8
Stomach	SNU1	8.9
Stomach	SNU216	8.2
Stomach	SNU520	8.1
Stomach	SNU5	8.4
Stomach	SNU601	8.6
Stomach	SNU620	7.8
Stomach	SNU668	8
Stomach	SNU719	8.5
Stomach	TGBC11TKB	7.8
Thyroid	8305C	8.7
Thyroid	8505C	8.4
Thyroid	BCPAP	8.7
Thyroid	BHT101	8
Thyroid	CAL62	8.7
Thyroid	CGTHW1	8.1
Thyroid	FTC133	9
Thyroid	FTC238	8.4
Thyroid	ML1	9.1
Thyroid	SW579	8.6
Thyroid	TT2609C02	8.5
Thyroid	TT	9.3
Upper aerodigestive tract	BHY	8.3
Upper aerodigestive tract	BICR16	8.3
Upper aerodigestive tract	BICR18	8.3
Upper aerodigestive tract	BICR22	7.9
Upper aerodigestive tract	BICR31	8.7
Upper aerodigestive tract	BICR56	8.7
Upper aerodigestive tract	BICR6	8.7
Upper aerodigestive tract	CAL27	8.5
Upper aerodigestive tract	CAL33	9.1
Upper aerodigestive tract	DETROIT562	8.3
Upper aerodigestive tract	FADU	9.1
Upper aerodigestive tract	HS840T	8.6
Upper aerodigestive tract	HSC2	8
Upper aerodigestive tract	HSC3	7.2
Upper aerodigestive tract	HSC4	7.9
Upper aerodigestive tract	PECAPJ15	8.5
Upper aerodigestive tract	PECAPJ34CLONEC12	8.3
Upper aerodigestive tract	PECAPJ41CLONED2	8.3
Upper aerodigestive tract	PECAPJ49	8.9
Upper aerodigestive tract	SCC15	7.9
Upper aerodigestive tract	SCC25	8.4
Upper aerodigestive tract	SCC4	8.9
Upper aerodigestive tract	SCC9	9.2
Upper aerodigestive tract	SNU1076	7.8
Upper aerodigestive tract	SNU1214	8.1
Upper aerodigestive tract	SNU46	9.2
Upper aerodigestive tract	SNU899	8.3
Upper aerodigestive tract	YD10B	8.7
Upper aerodigestive tract	YD38	8.3
Upper aerodigestive tract	YD8	9.2
Urinary tract	5637	8.4
Urinary tract	639V	8.8
Urinary tract	647V	8.5
Urinary tract	BC3C	8.9
Urinary tract	BFTC905	8.1
Urinary tract	CAL29	8.3
Urinary tract	HS172T	7.6
Urinary tract	HT1197	8
Urinary tract	HT1376	8.9
Urinary tract	J82	8.6
Urinary tract	JMSU1	8.3
Urinary tract	KMBC2	8.3
Urinary tract	KU1919	8.1
Urinary tract	RT11284	8.1
Urinary tract	RT112	8.1
Urinary tract	RT4	7.8
Urinary tract	SCABER	8.1
Urinary tract	SW1710	8.5
Urinary tract	SW780	8.6
Urinary tract	T24	8.8
Urinary tract	TCCSUP	8.9
Urinary tract	UMUC1	9.6
Urinary tract	UMUC3	7.8
Urinary tract	VMCUB1	8.7

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	12.8
Adrenal gland	17.9
Appendix	13.8
Bone marrow	10.4
Breast	9.8
Cerebral cortex	30.6
Cervix, uterine	19.9
Colon	10.6
Duodenum	9.1
Endometrium	24
Epididymis	9.4
Esophagus	28.6
Fallopian tube	25.6
Gallbladder	18.2
Heart muscle	13.1
Kidney	10.7
Liver	4.7
Lung	17.3
Lymph node	14.2
Ovary	19.9
Pancreas	4.2
Parathyroid gland	42.8
Placenta	15.7
Prostate	42.9
Rectum	10.8
Salivary gland	5.3
Seminal vesicle	17.8
Skeletal muscle	9.7
Skin	42.5
Small intestine	10.1
Smooth muscle	22.8
Spleen	16.3
Stomach	12.4
Testis	27.8
Thyroid gland	49.6
Tonsil	10.8
Urinary bladder	12.1

> Text Mining based Expression [ TOP ]
There is no record.

Summary
Symbol	GTF3C1
Name	general transcription factor IIIC subunit 1
Aliases	TFIIIC220; general transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD ); TFIIIC; TFIIICalpha; TF ......
Location	16p12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.678	1.25e-55	24.5	53	22.5	Neutral
BRCA	Breast invasive carcinoma	1075	0.565	8.64e-92	8.2	41.2	50.6	Gain
CESC	Cervical and endocervical cancers	292	0.546	4.45e-24	12.3	73.3	14.4	Neutral
COAD	Colon adenocarcinoma	449	0.365	1.45e-15	5.8	68.4	25.8	Neutral
ESCA	Esophageal carcinoma	183	0.432	1.06e-09	26.8	50.3	23	Neutral
GBM	Glioblastoma multiforme	147	0.319	8.27e-05	17	77.6	5.4	Neutral
HNSC	Head and Neck squamous cell carcinoma	514	0.517	1.96e-36	11.9	66.1	22	Neutral
KIRC	Kidney renal clear cell carcinoma	525	0.291	1.13e-11	2.3	77.1	20.6	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	0.581	2.35e-27	1	45.8	53.1	Gain
LAML	Acute Myeloid Leukemia	166	0.043	0.581	1.2	98.8	0	Neutral
LGG	Brain Lower Grade Glioma	513	0.305	1.75e-12	4.1	93.2	2.7	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.66	6.13e-47	24.5	63.2	12.4	Neutral
LUAD	Lung adenocarcinoma	512	0.447	1.47e-26	17.2	51.8	31.1	Neutral
LUSC	Lung squamous cell carcinoma	498	0.562	9.19e-43	26.5	50.8	22.7	Neutral
OV	Ovarian serous cystadenocarcinoma	300	0.562	2.41e-26	39.3	45.3	15.3	Loss
PAAD	Pancreatic adenocarcinoma	177	0.146	0.0528	5.1	81.4	13.6	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	0.469	2.97e-10	5.6	90.7	3.7	Neutral
PRAD	Prostate adenocarcinoma	491	0.21	2.74e-06	5.9	86.4	7.7	Neutral
READ	Rectum adenocarcinoma	164	0.474	1.39e-10	4.9	70.1	25	Neutral
SARC	Sarcoma	255	0.559	2.33e-22	23.1	55.7	21.2	Neutral
SKCM	Skin Cutaneous Melanoma	367	0.387	1.49e-14	15.8	66.2	18	Neutral
STAD	Stomach adenocarcinoma	413	0.475	1.2e-24	19.9	64.2	16	Neutral
TGCT	Testicular Germ Cell Tumors	150	0.133	0.104	29.3	60	10.7	Neutral
THCA	Thyroid carcinoma	497	0.164	0.000238	0.2	96.8	3	Neutral
THYM	Thymoma	119	0.225	0.0137	2.5	94.1	3.4	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.521	9.17e-39	11.9	77.8	10.2	Neutral

Summary
Symbol	GTF3C1
Name	general transcription factor IIIC subunit 1
Aliases	TFIIIC220; general transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD ); TFIIIC; TFIIICalpha; TF ......
Location	16p12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

[ TOP ]

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.322	1.43e-11	17	408	0.006	0.000563	NS/NA
BRCA	Breast invasive carcinoma	-0.305	4.17e-20	83	785	-0.007	0.000175	NS/NA
CESC	Cervical and endocervical cancers	-0.246	1.35e-05	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.126	0.0255	19	297	0.007	0.0674	NS/NA
ESCA	Esophageal carcinoma	-0.288	5.02e-05	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.183	0.144	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.145	0.00073	20	522	-0.007	0.274	NS/NA
KIRC	Kidney renal clear cell carcinoma	-0.171	0.00153	24	319	0.005	0.000303	NS/NA
KIRP	Kidney renal papillary cell carcinoma	-0.396	1.71e-12	23	275	0.001	0.439	NS/NA
LAML	Acute Myeloid Leukemia	-0.148	0.0539	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	-0.081	0.0637	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.41	0	41	373	0.004	2.86e-06	NS/NA
LUAD	Lung adenocarcinoma	-0.131	0.00423	21	456	-0.022	0.0464	NS/NA
LUSC	Lung squamous cell carcinoma	-0.282	2.96e-08	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	-0.967	0.000165	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.16	0.0306	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.214	0.0034	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.088	0.0431	35	498	-0.003	0.243	NS/NA
READ	Rectum adenocarcinoma	-0.118	0.241	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.22	0.000335	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.208	5.25e-06	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.256	6.44e-07	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.167	0.0375	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.106	0.012	50	509	-0.001	0.101	NS/NA
THYM	Thymoma	0.033	0.717	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.255	2.69e-08	34	431	-0.002	0.555	NS/NA

Summary
Symbol	GTF3C1
Name	general transcription factor IIIC subunit 1
Aliases	TFIIIC220; general transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD ); TFIIIC; TFIIICalpha; TF ......
Location	16p12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Level	Level Name
Adrenal gland	3	High
Appendix	2	Medium
Bone marrow	1	Low
Breast	3	High
Bronchus	3	High
Caudate	1	Low
Cerebellum	2	Medium
Cerebral cortex	2	Medium
Cervix, uterine	3	High
Colon	3	High
Duodenum	3	High
Endometrium	2	Medium
Epididymis	2	Medium
Esophagus	3	High
Fallopian tube	3	High
Gallbladder	3	High
Heart muscle	2	Medium
Hippocampus	2	Medium
Kidney	3	High
Liver	1	Low
Lung	3	High
Lymph node	3	High
Nasopharynx	3	High
Oral mucosa	3	High
Ovary	1	Low
Pancreas	2	Medium
Parathyroid gland	3	High
Placenta	3	High
Prostate	2	Medium
Rectum	3	High
Salivary gland	3	High
Seminal vesicle	2	Medium
Skeletal muscle	2	Medium
Skin	3	High
Small intestine	3	High
Smooth muscle	2	Medium
Soft tissue	1	Low
Spleen	1	Low
Stomach	3	High
Testis	3	High
Thyroid gland	3	High
Tonsil	2	Medium
Urinary bladder	3	High
Vagina	3	High

Summary
Symbol	GTF3C1
Name	general transcription factor IIIC subunit 1
Aliases	TFIIIC220; general transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD ); TFIIIC; TFIIICalpha; TF ......
Location	16p12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.0216	Significant	24476821
BRCA	Breast invasive carcinoma	521	5.02e-20	Significant	23000897
COAD	Colon adenocarcinoma	149	0.046	Significant	22810696
GBM	Glioblastoma multiforme	157	0.063	NS	26824661
HNSC	Head and Neck squamous cell carcinoma	279	0.148	NS	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.00607	Significant	26536169
LGG	Brain Lower Grade Glioma	513	0.000523	Significant	26824661
LUAD	Lung adenocarcinoma	230	0.774	NS	25079552
LUSC	Lung squamous cell carcinoma	178	0.146	NS	22960745
OV	Ovarian serous cystadenocarcinoma	287	0.00107	Significant	21720365
PRAD	Prostate adenocarcinoma	333	0.119	NS	26544944
READ	Rectum adenocarcinoma	67	0.168	NS	22810696
SKCM	Skin Cutaneous Melanoma	315	0.118	NS	26091043
STAD	Stomach adenocarcinoma	277	0.00138	Significant	25079317
THCA	Thyroid carcinoma	391	8.61e-31	Significant	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	0.0865	NS	23636398

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	1.407	0.105	NS
BRCA	Breast invasive carcinoma	1079	1.549	0.0519	NS
CESC	Cervical and endocervical cancers	291	0.744	0.383	NS
COAD	Colon adenocarcinoma	439	1.051	0.875	NS
ESCA	Esophageal carcinoma	184	0.739	0.336	NS
GBM	Glioblastoma multiforme	158	0.839	0.474	NS
HNSC	Head and Neck squamous cell carcinoma	518	0.86	0.449	NS
KIRC	Kidney renal clear cell carcinoma	531	1.01	0.965	NS
KIRP	Kidney renal papillary cell carcinoma	287	0.913	0.838	NS
LAML	Acute Myeloid Leukemia	149	1.851	0.0358	Shorter
LGG	Brain Lower Grade Glioma	511	1.416	0.167	NS
LIHC	Liver hepatocellular carcinoma	365	1.29	0.32	NS
LUAD	Lung adenocarcinoma	502	1.531	0.0426	Shorter
LUSC	Lung squamous cell carcinoma	494	0.832	0.361	NS
OV	Ovarian serous cystadenocarcinoma	303	0.938	0.763	NS
PAAD	Pancreatic adenocarcinoma	177	0.57	0.0478	Longer
PCPG	Pheochromocytoma and Paraganglioma	179	0.502	0.567	NS
PRAD	Prostate adenocarcinoma	497	0.649	0.633	NS
READ	Rectum adenocarcinoma	159	0.342	0.126	NS
SARC	Sarcoma	259	1.728	0.0534	NS
SKCM	Skin Cutaneous Melanoma	459	1.65	0.00803	Shorter
STAD	Stomach adenocarcinoma	388	0.856	0.48	NS
TGCT	Testicular Germ Cell Tumors	134	1568764907.383	0.164	NS
THCA	Thyroid carcinoma	500	3.003	0.108	NS
THYM	Thymoma	119	0.241	0.19	NS
UCEC	Uterine Corpus Endometrial Carcinoma	543	0.852	0.581	NS

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	0.034	0.494	NS
BRCA	Breast invasive carcinoma	1071	0.087	0.00456	Higher
CESC	Cervical and endocervical cancers	167	0.049	0.533	NS
COAD	Colon adenocarcinoma	445	0.086	0.0689	NS
ESCA	Esophageal carcinoma	162	-0.127	0.107	NS
HNSC	Head and Neck squamous cell carcinoma	448	0.016	0.734	NS
KIRC	Kidney renal clear cell carcinoma	531	-0.038	0.378	NS
KIRP	Kidney renal papillary cell carcinoma	260	0.127	0.0407	Higher
LIHC	Liver hepatocellular carcinoma	347	0.174	0.00112	Higher
LUAD	Lung adenocarcinoma	507	0.024	0.593	NS
LUSC	Lung squamous cell carcinoma	497	0.021	0.648	NS
OV	Ovarian serous cystadenocarcinoma	302	-0.129	0.0253	Lower
PAAD	Pancreatic adenocarcinoma	176	-0.121	0.109	NS
READ	Rectum adenocarcinoma	156	0.015	0.848	NS
SKCM	Skin Cutaneous Melanoma	410	-0.061	0.214	NS
STAD	Stomach adenocarcinoma	392	0.011	0.823	NS
TGCT	Testicular Germ Cell Tumors	81	0.26	0.0192	Higher
THCA	Thyroid carcinoma	499	-0.049	0.275	NS
UCEC	Uterine Corpus Endometrial Carcinoma	501	-0.033	0.467	NS

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	-0.054	0.372	NS
HNSC	Head and Neck squamous cell carcinoma	498	-0.285	9.58e-11	Lower
KIRC	Kidney renal clear cell carcinoma	525	0.077	0.0786	NS
LGG	Brain Lower Grade Glioma	514	0.068	0.123	NS
LIHC	Liver hepatocellular carcinoma	366	0.003	0.95	NS
OV	Ovarian serous cystadenocarcinoma	296	-0.027	0.643	NS
PAAD	Pancreatic adenocarcinoma	176	0.028	0.715	NS
STAD	Stomach adenocarcinoma	406	0.012	0.816	NS
UCEC	Uterine Corpus Endometrial Carcinoma	534	0.115	0.00796	Higher

Summary
Symbol	GTF3C1
Name	general transcription factor IIIC subunit 1
Aliases	TFIIIC220; general transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD ); TFIIIC; TFIIICalpha; TF ......
Location	16p12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	GTF3C1
Name	general transcription factor IIIC subunit 1
Aliases	TFIIIC220; general transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD ); TFIIIC; TFIIICalpha; TF ......
Location	16p12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for GTF3C1.

Summary
Symbol	GTF3C1
Name	general transcription factor IIIC subunit 1
Aliases	TFIIIC220; general transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD ); TFIIIC; TFIIICalpha; TF ......
Location	16p12.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining [ TOP ]
There is no record for GTF3C1.