CR2Cancer

Summary
Symbol	JMJD1C
Name	jumonji domain containing 1C
Aliases	DKFZp761F0118; KIAA1380; FLJ14374; TRIP8; thyroid hormone receptor interactor 8; TR-interacting protein 8; T ......
Location	10q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

[ TOP ]

Domain

PF02373 JmjC domain

Function

Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity).

Classification

Class	Modification	Substrate	Product	PubMed
Histone modification erase	Histone methylation	H3K9me	H3K9	17549425

> Gene Ontology [ TOP ]
Biological Process	GO:0006482 protein demethylation GO:0007596 blood coagulation GO:0007599 hemostasis GO:0008214 protein dealkylation GO:0016570 histone modification GO:0016577 histone demethylation GO:0033169 histone H3-K9 demethylation GO:0050817 coagulation GO:0050878 regulation of body fluid levels GO:0070076 histone lysine demethylation GO:0070988 demethylation
Molecular Function	GO:0003682 chromatin binding GO:0008134 transcription factor binding GO:0031490 chromatin DNA binding GO:0032451 demethylase activity GO:0032452 histone demethylase activity GO:0032454 histone demethylase activity (H3-K9 specific) GO:0035257 nuclear hormone receptor binding GO:0043566 structure-specific DNA binding GO:0046966 thyroid hormone receptor binding GO:0051213 dioxygenase activity GO:0051427 hormone receptor binding
Cellular Component	GO:0000785 chromatin

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	R-HSA-983231: Factors involved in megakaryocyte development and platelet production R-HSA-109582: Hemostasis

Summary
Symbol	JMJD1C
Name	jumonji domain containing 1C
Aliases	DKFZp761F0118; KIAA1380; FLJ14374; TRIP8; thyroid hormone receptor interactor 8; TR-interacting protein 8; T ......
Location	10q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM458811	c.6193C>T	p.H2065Y	Substitution - Missense	Cervix
COSM1348591	c.2342T>C	p.V781A	Substitution - Missense	Large_intestine
COSM4420553	c.2671C>A	p.P891T	Substitution - Missense	Central_nervous_system
COSM4693841	c.3111A>G	p.E1037E	Substitution - coding silent	Large_intestine
COSM3439593	c.136C>T	p.R46C	Substitution - Missense	Skin
COSM919456	c.5737A>C	p.N1913H	Substitution - Missense	Endometrium
COSM266735	c.5189T>C	p.M1730T	Substitution - Missense	Large_intestine
COSM4693843	c.2990G>A	p.S997N	Substitution - Missense	Large_intestine
COSM4435799	c.6466A>G	p.I2156V	Substitution - Missense	Oesophagus
COSM3439591	c.540T>A	p.N180K	Substitution - Missense	Skin
COSM5769555	c.4667C>T	p.S1556F	Substitution - Missense	Breast
COSM4693833	c.4870C>T	p.R1624W	Substitution - Missense	Large_intestine
COSM919454	c.5912C>T	p.A1971V	Substitution - Missense	Large_intestine
COSM2158449	c.3934A>C	p.N1312H	Substitution - Missense	Large_intestine
COSM5016316	c.5404_5406delGAA	p.E1802delE	Deletion - In frame	Kidney
COSM2158391	c.5488C>T	p.R1830W	Substitution - Missense	Large_intestine
COSM5733006	c.6338G>A	p.G2113D	Substitution - Missense	Pancreas
COSM2158493	c.2675C>T	p.S892F	Substitution - Missense	Large_intestine
COSM1297355	c.781C>T	p.P261S	Substitution - Missense	Urinary_tract
COSM5005276	c.2727G>A	p.A909A	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM1348577	c.5364delA	p.E1789fs*45	Deletion - Frameshift	Large_intestine
COSM919469	c.4697G>T	p.S1566I	Substitution - Missense	Endometrium
COSM1316372	c.299G>A	p.S100N	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM88110	c.125G>A	p.R42Q	Substitution - Missense	Large_intestine
COSM4441103	c.3938C>T	p.S1313F	Substitution - Missense	Large_intestine
COSM5653525	c.1208C>G	p.T403S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4789700	c.3212A>T	p.H1071L	Substitution - Missense	Liver
COSM4883152	c.1982C>A	p.S661Y	Substitution - Missense	Upper_aerodigestive_tract
COSM3807460	c.6209T>G	p.F2070C	Substitution - Missense	Breast
COSM1745840	c.73G>C	p.D25H	Substitution - Missense	Urinary_tract
COSM4015110	c.3838G>A	p.A1280T	Substitution - Missense	Stomach
COSM240278	c.6332A>T	p.Y2111F	Substitution - Missense	Prostate
COSM919485	c.3457T>G	p.F1153V	Substitution - Missense	Endometrium
COSM1474700	c.2371G>A	p.E791K	Substitution - Missense	Breast
COSM4693849	c.613G>A	p.E205K	Substitution - Missense	Large_intestine
COSM4915651	c.4293C>G	p.Y1431*	Substitution - Nonsense	Liver
COSM4015122	c.2521A>G	p.K841E	Substitution - Missense	Stomach
COSM4849694	c.920C>T	p.S307L	Substitution - Missense	Cervix
COSM465841	c.5643A>G	p.E1881E	Substitution - coding silent	Kidney
COSM3738676	c.6508C>A	p.Q2170K	Substitution - Missense	Liver
COSM4959403	c.4105G>A	p.A1369T	Substitution - Missense	Liver
COSM4383457	c.2347A>C	p.N783H	Substitution - Missense	Large_intestine
COSM3790883	c.4426C>T	p.P1476S	Substitution - Missense	Urinary_tract
COSM3998050	c.890C>A	p.T297N	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4881150	c.1521T>G	p.A507A	Substitution - coding silent	Prostate
COSM3368095	c.1357A>T	p.R453*	Substitution - Nonsense	Thyroid
COSM4015096	c.5584A>G	p.S1862G	Substitution - Missense	Stomach
COSM4636216	c.463G>C	p.D155H	Substitution - Missense	Large_intestine
COSM1470411	c.3585A>C	p.S1195S	Substitution - coding silent	Prostate
COSM4795043	c.5802G>A	p.K1934K	Substitution - coding silent	Liver
COSM4693851	c.469_470insT	p.S157fs*2	Insertion - Frameshift	Large_intestine
COSM3665807	c.1022A>G	p.D341G	Substitution - Missense	Liver
COSM3397207	c.5061A>T	p.Q1687H	Substitution - Missense	Central_nervous_system
COSM3415169	c.2414G>A	p.R805Q	Substitution - Missense	Large_intestine
COSM4756569	c.6275A>G	p.D2092G	Substitution - Missense	Stomach
COSM287251	c.5759T>C	p.I1920T	Substitution - Missense	Large_intestine
COSM325576	c.4083G>T	p.K1361N	Substitution - Missense	Lung
COSM138766	c.4835C>T	p.A1612V	Substitution - Missense	Skin
COSM1603625	c.4178A>C	p.K1393T	Substitution - Missense	Liver
COSM1242397	c.127C>T	p.R43C	Substitution - Missense	Oesophagus
COSM2158595	c.629delA	p.N210fs*32	Deletion - Frameshift	Large_intestine
COSM3439581	c.2625C>T	p.F875F	Substitution - coding silent	Skin
COSM919454	c.5912C>T	p.A1971V	Substitution - Missense	Endometrium
COSM1128024	c.6894G>C	p.E2298D	Substitution - Missense	Prostate
COSM1128024	c.6894G>C	p.E2298D	Substitution - Missense	Large_intestine
COSM1128024	c.6894G>C	p.E2298D	Substitution - Missense	Breast
COSM919465	c.4890T>C	p.C1630C	Substitution - coding silent	Endometrium
COSM3709875	c.4987+1G>T	p.?	Unknown	Upper_aerodigestive_tract
COSM3985684	c.2232T>C	p.F744F	Substitution - coding silent	Kidney
COSM3415169	c.2414G>A	p.R805Q	Substitution - Missense	Biliary_tract
COSM919452	c.6119G>A	p.R2040K	Substitution - Missense	Endometrium
COSM919517	c.445C>T	p.R149*	Substitution - Nonsense	Endometrium
COSM384723	c.129C>A	p.R43R	Substitution - coding silent	Lung
COSM4626675	c.2047A>T	p.S683C	Substitution - Missense	Large_intestine
COSM4693835	c.4362T>C	p.V1454V	Substitution - coding silent	Large_intestine
COSM1627572	c.4765A>G	p.I1589V	Substitution - Missense	Liver
COSM4015106	c.4651A>G	p.I1551V	Substitution - Missense	Stomach
COSM3395976	c.1935G>T	p.W645C	Substitution - Missense	Prostate
COSM5611800	c.4233C>G	p.D1411E	Substitution - Missense	Adrenal_gland
COSM5783836	c.2599C>T	p.Q867*	Substitution - Nonsense	Breast
COSM4800813	c.6641T>C	p.I2214T	Substitution - Missense	Liver
COSM2158501	c.2448T>C	p.F816F	Substitution - coding silent	Skin
COSM4455471	c.130A>G	p.R44G	Substitution - Missense	Skin
COSM5969868	c.3157T>C	p.L1053L	Substitution - coding silent	Upper_aerodigestive_tract
COSM77922	c.5052G>A	p.M1684I	Substitution - Missense	Ovary
COSM465837	c.6569A>T	p.Q2190L	Substitution - Missense	Kidney
COSM4800813	c.6641T>C	p.I2214T	Substitution - Missense	Adrenal_gland
COSM919460	c.5495T>C	p.L1832S	Substitution - Missense	Endometrium
COSM2158493	c.2675C>T	p.S892F	Substitution - Missense	Large_intestine
COSM5640136	c.5178T>C	p.N1726N	Substitution - coding silent	Oesophagus
COSM4800813	c.6641T>C	p.I2214T	Substitution - Missense	Liver
COSM50785	c.2731G>A	p.A911T	Substitution - Missense	Breast
COSM4015086	c.6410A>G	p.D2137G	Substitution - Missense	Stomach
COSM4144785	c.4328G>A	p.G1443D	Substitution - Missense	Thyroid
COSM3807464	c.4681G>C	p.D1561H	Substitution - Missense	Breast
COSM4015092	c.6212T>C	p.V2071A	Substitution - Missense	Stomach
COSM1675286	c.2206A>G	p.K736E	Substitution - Missense	Large_intestine
COSM4937826	c.3687C>T	p.C1229C	Substitution - coding silent	Liver
COSM6013897	c.1196C>T	p.P399L	Substitution - Missense	Skin
COSM1348577	c.5364delA	p.E1789fs*45	Deletion - Frameshift	Large_intestine
COSM194167	c.2419C>T	p.L807F	Substitution - Missense	Urinary_tract
COSM919481	c.3716T>A	p.L1239*	Substitution - Nonsense	Endometrium
COSM2158575	c.1020_1021insA	p.D341fs*3	Insertion - Frameshift	Large_intestine
COSM5791908	c.4857A>C	p.A1619A	Substitution - coding silent	Breast
COSM4796387	c.903G>A	p.K301K	Substitution - coding silent	Liver
COSM1211265	c.3761T>G	p.F1254C	Substitution - Missense	Large_intestine
COSM3395978	c.1934G>A	p.W645*	Substitution - Nonsense	Prostate
COSM1745838	c.4027G>A	p.D1343N	Substitution - Missense	Urinary_tract
COSM5999043	c.419A>G	p.E140G	Substitution - Missense	Prostate
COSM71236	c.5563T>C	p.Y1855H	Substitution - Missense	Ovary
COSM4793854	c.4228G>A	p.G1410R	Substitution - Missense	Liver
COSM5007311	c.3210G>A	p.W1070*	Substitution - Nonsense	Large_intestine
COSM3751894	c.6489C>G	p.D2163E	Substitution - Missense	Large_intestine
COSM5940041	c.5605C>T	p.P1869S	Substitution - Missense	Skin
COSM4649831	c.509T>C	p.I170T	Substitution - Missense	Large_intestine
COSM3415173	c.1337G>A	p.S446N	Substitution - Missense	Large_intestine
COSM4790562	c.5162A>G	p.N1721S	Substitution - Missense	Liver
COSM684716	c.139G>A	p.A47T	Substitution - Missense	Lung
COSM2158577	c.1020delA	p.D341fs*10	Deletion - Frameshift	Stomach
COSM919491	c.2528A>G	p.H843R	Substitution - Missense	Endometrium
COSM4573706	c.1380T>C	p.H460H	Substitution - coding silent	Bone
COSM4015132	c.150C>T	p.N50N	Substitution - coding silent	Stomach
COSM919493	c.2477A>T	p.E826V	Substitution - Missense	Endometrium
COSM3439589	c.1700C>T	p.P567L	Substitution - Missense	Skin
COSM4533358	c.1314G>T	p.K438N	Substitution - Missense	Skin
COSM1316370	c.308C>G	p.P103R	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3368091	c.1584C>A	p.T528T	Substitution - coding silent	Thyroid
COSM5802112	c.6799delA	p.I2267fs*21	Deletion - Frameshift	Breast
COSM5637734	c.6025T>C	p.S2009P	Substitution - Missense	Oesophagus
COSM3807472	c.2680G>T	p.E894*	Substitution - Nonsense	Breast
COSM2158451	c.3924T>C	p.I1308I	Substitution - coding silent	Large_intestine
COSM3699932	c.6849C>T	p.V2283V	Substitution - coding silent	Liver
COSM1348577	c.5364delA	p.E1789fs*45	Deletion - Frameshift	Pancreas
COSM1348577	c.5364delA	p.E1789fs*45	Deletion - Frameshift	Large_intestine
COSM2158379	c.5797C>T	p.L1933F	Substitution - Missense	Large_intestine
COSM919458	c.5520A>G	p.L1840L	Substitution - coding silent	Endometrium
COSM4015126	c.1463A>C	p.K488T	Substitution - Missense	Stomach
COSM919503	c.1489G>A	p.D497N	Substitution - Missense	Endometrium
COSM1627570	c.5678A>G	p.N1893S	Substitution - Missense	Liver
COSM4915691	c.5460C>T	p.S1820S	Substitution - coding silent	Liver
COSM3686818	c.423G>T	p.K141N	Substitution - Missense	Large_intestine
COSM3935124	c.3094C>G	p.P1032A	Substitution - Missense	Oesophagus
COSM4015084	c.6595C>T	p.R2199C	Substitution - Missense	Stomach
COSM4144787	c.4322G>A	p.R1441K	Substitution - Missense	Thyroid
COSM4392383	c.2550T>C	p.D850D	Substitution - coding silent	Prostate
COSM4015094	c.5598G>A	p.R1866R	Substitution - coding silent	Stomach
COSM3790879	c.6400G>A	p.D2134N	Substitution - Missense	Urinary_tract
COSM919501	c.1765T>G	p.L589V	Substitution - Missense	Endometrium
COSM5782530	c.4213T>C	p.S1405P	Substitution - Missense	Breast
COSM3439577	c.4410C>T	p.N1470N	Substitution - coding silent	Skin
COSM5831485	c.4656_4657insAT	p.G1553fs*14	Insertion - Frameshift	Breast
COSM4693845	c.2738A>C	p.N913T	Substitution - Missense	Large_intestine
COSM4015108	c.3902G>A	p.S1301N	Substitution - Missense	Stomach
COSM371252	c.2441C>T	p.A814V	Substitution - Missense	Lung
COSM919523	c.263G>T	p.R88I	Substitution - Missense	Endometrium
COSM3415175	c.446G>A	p.R149Q	Substitution - Missense	Large_intestine
COSM4015102	c.5028G>A	p.Q1676Q	Substitution - coding silent	Stomach
COSM1255161	c.964G>C	p.V322L	Substitution - Missense	Stomach
COSM1348595	c.892A>G	p.N298D	Substitution - Missense	Large_intestine
COSM5370946	c.5227C>T	p.P1743S	Substitution - Missense	Skin
COSM5963292	c.4824G>A	p.V1608V	Substitution - coding silent	Breast
COSM4976741	c.5314C>T	p.L1772L	Substitution - coding silent	Oesophagus
COSM4796387	c.903G>A	p.K301K	Substitution - coding silent	Liver
COSM4896656	c.385T>G	p.L129V	Substitution - Missense	Skin
COSM3935118	c.6086C>T	p.S2029L	Substitution - Missense	Oesophagus
COSM146944	c.890C>G	p.T297S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM919515	c.591C>A	p.P197P	Substitution - coding silent	Endometrium
COSM4849931	c.1265C>T	p.S422L	Substitution - Missense	Cervix
COSM3439583	c.2443C>T	p.P815S	Substitution - Missense	Skin
COSM4805496	c.6686A>G	p.H2229R	Substitution - Missense	Liver
COSM919505	c.1418G>A	p.R473Q	Substitution - Missense	Endometrium
COSM146945	c.722T>C	p.M241T	Substitution - Missense	Stomach
COSM2158379	c.5797C>T	p.L1933F	Substitution - Missense	Large_intestine
COSM465843	c.5497C>T	p.L1833L	Substitution - coding silent	Central_nervous_system
COSM5625729	c.3832A>G	p.S1278G	Substitution - Missense	Oesophagus
COSM5770864	c.6365C>T	p.S2122L	Substitution - Missense	Breast
COSM282042	c.6411C>G	p.D2137E	Substitution - Missense	Large_intestine
COSM3807468	c.3578G>T	p.G1193V	Substitution - Missense	Breast
COSM919483	c.3703G>A	p.A1235T	Substitution - Missense	Endometrium
COSM4015118	c.3033A>G	p.P1011P	Substitution - coding silent	Stomach
COSM4693829	c.5603T>C	p.M1868T	Substitution - Missense	Large_intestine
COSM3375507	c.1884A>T	p.Q628H	Substitution - Missense	Pancreas
COSM5657290	c.272G>C	p.R91P	Substitution - Missense	Soft_tissue
COSM5370942	c.6292C>T	p.L2098F	Substitution - Missense	Skin
COSM1675286	c.2206A>G	p.K736E	Substitution - Missense	Large_intestine
COSM2158443	c.3967A>C	p.S1323R	Substitution - Missense	Upper_aerodigestive_tract
COSM3807470	c.3388G>A	p.G1130R	Substitution - Missense	Breast
COSM1627572	c.4765A>G	p.I1589V	Substitution - Missense	Upper_aerodigestive_tract
COSM4387384	c.5206-9A>G	p.?	Unknown	Lung
COSM2158479	c.3114A>C	p.P1038P	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM2158401	c.5306A>T	p.Q1769L	Substitution - Missense	Oesophagus
COSM4453499	c.2383A>G	p.R795G	Substitution - Missense	Skin
COSM919473	c.4446T>G	p.D1482E	Substitution - Missense	Endometrium
COSM919497	c.1956T>C	p.H652H	Substitution - coding silent	Endometrium
COSM4693839	c.3665C>T	p.P1222L	Substitution - Missense	Large_intestine
COSM684734	c.6303A>G	p.E2101E	Substitution - coding silent	Lung
COSM4179520	c.2819T>A	p.L940*	Substitution - Nonsense	Large_intestine
COSM5732519	c.6210delT	p.F2070fs*6	Deletion - Frameshift	Pancreas
COSM88110	c.125G>A	p.R42Q	Substitution - Missense	Central_nervous_system
COSM3726565	c.6609T>C	p.L2203L	Substitution - coding silent	Lung
COSM4144783	c.4329T>A	p.G1443G	Substitution - coding silent	Thyroid
COSM4387245	c.2203C>A	p.H735N	Substitution - Missense	Lung
COSM5753517	c.5356G>A	p.E1786K	Substitution - Missense	Large_intestine
COSM4413600	c.1980_1981TT>GC	p.S661P	Substitution - Missense	Genital_tract
COSM1348597	c.157G>A	p.A53T	Substitution - Missense	Large_intestine
COSM4793854	c.4228G>A	p.G1410R	Substitution - Missense	Liver
COSM5785669	c.5215C>T	p.Q1739*	Substitution - Nonsense	Breast
COSM3867597	c.1720C>T	p.P574S	Substitution - Missense	Skin
COSM919477	c.4031A>C	p.K1344T	Substitution - Missense	Endometrium
COSM4437756	c.727A>G	p.I243V	Substitution - Missense	Oesophagus
COSM1638611	c.3694A>G	p.S1232G	Substitution - Missense	Stomach
COSM4015116	c.3212A>G	p.H1071R	Substitution - Missense	Stomach
COSM1316368	c.345T>G	p.Y115*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM3368093	c.1546C>T	p.Q516*	Substitution - Nonsense	Thyroid
COSM2158575	c.1020_1021insA	p.D341fs*3	Insertion - Frameshift	Large_intestine
COSM5475451	c.672T>C	p.H224H	Substitution - coding silent	Large_intestine
COSM3415175	c.446G>A	p.R149Q	Substitution - Missense	Large_intestine
COSM3439575	c.5056A>G	p.T1686A	Substitution - Missense	Skin
COSM4015090	c.6217C>T	p.P2073S	Substitution - Missense	Stomach
COSM118587	c.300C>T	p.S100S	Substitution - coding silent	Ovary
COSM4430901	c.5739T>C	p.N1913N	Substitution - coding silent	Oesophagus
COSM1603625	c.4178A>C	p.K1393T	Substitution - Missense	Liver
COSM5969870	c.1112A>G	p.N371S	Substitution - Missense	Upper_aerodigestive_tract
COSM2158519	c.1981T>C	p.S661P	Substitution - Missense	Soft_tissue
COSM2158553	c.1554T>C	p.P518P	Substitution - coding silent	Large_intestine
COSM3807476	c.887A>C	p.D296A	Substitution - Missense	Breast
COSM1348581	c.5224C>A	p.P1742T	Substitution - Missense	Large_intestine
COSM1348577	c.5364delA	p.E1789fs*45	Deletion - Frameshift	Large_intestine
COSM919493	c.2477A>T	p.E826V	Substitution - Missense	Large_intestine
COSM2158475	c.3163G>A	p.E1055K	Substitution - Missense	Large_intestine
COSM1638611	c.3694A>G	p.S1232G	Substitution - Missense	Stomach
COSM3439579	c.3702A>G	p.T1234T	Substitution - coding silent	Skin
COSM5483475	c.3476G>A	p.G1159D	Substitution - Missense	Large_intestine
COSM1603623	c.4415A>G	p.N1472S	Substitution - Missense	Liver
COSM5753519	c.2539C>T	p.Q847*	Substitution - Nonsense	Large_intestine
COSM3368089	c.3745C>T	p.Q1249*	Substitution - Nonsense	Thyroid
COSM5785189	c.1714C>T	p.H572Y	Substitution - Missense	Breast
COSM919489	c.3109G>A	p.E1037K	Substitution - Missense	Endometrium
COSM465843	c.5497C>T	p.L1833L	Substitution - coding silent	Kidney
COSM1739652	c.6106A>G	p.M2036V	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3395978	c.1934G>A	p.W645*	Substitution - Nonsense	Prostate
COSM4693831	c.5451T>G	p.P1817P	Substitution - coding silent	Large_intestine
COSM2158429	c.4179A>T	p.K1393N	Substitution - Missense	Large_intestine
COSM4936757	c.5206-10C>T	p.?	Unknown	Prostate
COSM684720	c.3004G>T	p.E1002*	Substitution - Nonsense	Lung
COSM2158379	c.5797C>T	p.L1933F	Substitution - Missense	Large_intestine
COSM919517	c.445C>T	p.R149*	Substitution - Nonsense	Breast
COSM2158447	c.3932_3940delCAAACTCTG	p.A1311_S1313delANS	Deletion - In frame	Large_intestine
COSM1348593	c.2222G>T	p.R741I	Substitution - Missense	Large_intestine
COSM2158471	c.3408T>A	p.I1136I	Substitution - coding silent	Oesophagus
COSM71235	c.6212T>A	p.V2071E	Substitution - Missense	Ovary
COSM343876	c.4774G>A	p.D1592N	Substitution - Missense	Lung
COSM1662338	c.934C>A	p.L312I	Substitution - Missense	Kidney
COSM919507	c.1035C>T	p.S345S	Substitution - coding silent	Endometrium
COSM4413449	c.5721A>G	p.I1907M	Substitution - Missense	Genital_tract
COSM3415171	c.2413C>T	p.R805*	Substitution - Nonsense	Large_intestine
COSM1745840	c.73G>C	p.D25H	Substitution - Missense	Urinary_tract
COSM213520	c.859C>G	p.P287A	Substitution - Missense	Breast
COSM1603623	c.4415A>G	p.N1472S	Substitution - Missense	Liver
COSM1732380	c.4527A>C	p.L1509F	Substitution - Missense	Soft_tissue
COSM1128024	c.6894G>C	p.E2298D	Substitution - Missense	Prostate
COSM4889484	c.1060G>A	p.D354N	Substitution - Missense	Upper_aerodigestive_tract
COSM2158439	c.4066G>T	p.V1356L	Substitution - Missense	Large_intestine
COSM1644692	c.6860T>C	p.V2287A	Substitution - Missense	Salivary_gland
COSM5887370	c.5207C>T	p.S1736F	Substitution - Missense	Skin
COSM1187952	c.5376A>C	p.E1792D	Substitution - Missense	Lung
COSM3807474	c.1082C>G	p.T361R	Substitution - Missense	Breast
COSM465847	c.4882G>A	p.D1628N	Substitution - Missense	Kidney
COSM3415169	c.2414G>A	p.R805Q	Substitution - Missense	Large_intestine
COSM336345	c.1116G>T	p.M372I	Substitution - Missense	Lung
COSM4413451	c.4124T>C	p.I1375T	Substitution - Missense	Genital_tract
COSM3807478	c.122C>A	p.S41*	Substitution - Nonsense	Breast
COSM3395976	c.1935G>T	p.W645C	Substitution - Missense	Prostate
COSM4015124	c.2133A>G	p.A711A	Substitution - coding silent	Stomach
COSM3439571	c.5748A>C	p.L1916F	Substitution - Missense	Skin
COSM3985688	c.665A>C	p.K222T	Substitution - Missense	Kidney
COSM5518979	c.1019_1020insA	p.D341fs*3	Insertion - Frameshift	Biliary_tract
COSM1603619	c.5990A>T	p.N1997I	Substitution - Missense	Liver
COSM1348577	c.5364delA	p.E1789fs*45	Deletion - Frameshift	Stomach
COSM4936757	c.5206-10C>T	p.?	Unknown	Liver
COSM3867599	c.591C>T	p.P197P	Substitution - coding silent	Skin
COSM4693837	c.4209T>C	p.Y1403Y	Substitution - coding silent	Large_intestine
COSM139835	c.2000C>A	p.P667Q	Substitution - Missense	Skin
COSM5810186	c.6450T>A	p.P2150P	Substitution - coding silent	Liver
COSM684726	c.3326G>A	p.R1109H	Substitution - Missense	Lung
COSM5050275	c.5597G>A	p.R1866Q	Substitution - Missense	Stomach
COSM5955265	c.4371G>A	p.R1457R	Substitution - coding silent	Upper_aerodigestive_tract
COSM4015114	c.3265C>T	p.R1089C	Substitution - Missense	Stomach
COSM3790881	c.5209C>T	p.Q1737*	Substitution - Nonsense	Urinary_tract
COSM126754	c.2350C>T	p.Q784*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM1211273	c.4993G>T	p.E1665*	Substitution - Nonsense	Large_intestine
COSM465845	c.5006G>C	p.W1669S	Substitution - Missense	Kidney
COSM4438234	c.353G>T	p.R118L	Substitution - Missense	Oesophagus
COSM1297349	c.5374G>A	p.E1792K	Substitution - Missense	Urinary_tract
COSM1675284	c.5308T>C	p.S1770P	Substitution - Missense	Skin
COSM5801813	c.1674_1675insT	p.N559fs*1	Insertion - Frameshift	Breast
COSM919525	c.151G>A	p.V51I	Substitution - Missense	Endometrium
COSM1171707	c.6329T>G	p.V2110G	Substitution - Missense	Oesophagus
COSM4015120	c.2823A>G	p.V941V	Substitution - coding silent	Stomach
COSM5094915	c.2336A>T	p.D779V	Substitution - Missense	Thymus
COSM146944	c.890C>G	p.T297S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4481841	c.1892C>T	p.P631L	Substitution - Missense	Skin
COSM4015100	c.5035G>A	p.D1679N	Substitution - Missense	Stomach
COSM3395976	c.1935G>T	p.W645C	Substitution - Missense	Prostate
COSM231212	c.6705C>A	p.H2235Q	Substitution - Missense	Skin
COSM118949	c.4619+1G>T	p.?	Unknown	Ovary
COSM4015098	c.5253C>T	p.S1751S	Substitution - coding silent	Stomach
COSM1348587	c.4202G>T	p.R1401I	Substitution - Missense	Large_intestine
COSM3358806	c.3752G>A	p.S1251N	Substitution - Missense	Kidney
COSM684718	c.689G>A	p.R230Q	Substitution - Missense	Lung
COSM4431553	c.418G>C	p.E140Q	Substitution - Missense	Oesophagus
COSM919471	c.4547G>T	p.R1516I	Substitution - Missense	Endometrium
COSM919493	c.2477A>T	p.E826V	Substitution - Missense	Large_intestine
COSM1316366	c.349T>G	p.S117A	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5550913	c.3637T>C	p.C1213R	Substitution - Missense	Prostate
COSM3439587	c.2335G>A	p.D779N	Substitution - Missense	Skin
COSM5807661	c.3821A>T	p.Q1274L	Substitution - Missense	Liver
COSM1662336	c.1060G>C	p.D354H	Substitution - Missense	Kidney
COSM1603621	c.5571_5572insCAATG	p.G1858fs*20	Insertion - Frameshift	Liver
COSM5442775	c.2294C>T	p.S765L	Substitution - Missense	Oesophagus
COSM4165522	c.4079T>G	p.I1360S	Substitution - Missense	Kidney
COSM4836265	c.340G>A	p.D114N	Substitution - Missense	Cervix
COSM1603627	c.1000T>G	p.F334V	Substitution - Missense	Liver
COSM3981068	c.3481G>C	p.V1161L	Substitution - Missense	Ovary
COSM4959403	c.4105G>A	p.A1369T	Substitution - Missense	Liver
COSM5769555	c.4667C>T	p.S1556F	Substitution - Missense	Breast
COSM1603619	c.5990A>T	p.N1997I	Substitution - Missense	Liver
COSM919475	c.4299G>T	p.K1433N	Substitution - Missense	Endometrium
COSM4994588	c.5111T>G	p.L1704R	Substitution - Missense	Large_intestine
COSM1675286	c.2206A>G	p.K736E	Substitution - Missense	Large_intestine
COSM390429	c.3801G>T	p.K1267N	Substitution - Missense	Lung
COSM4015128	c.661G>A	p.D221N	Substitution - Missense	Stomach
COSM684732	c.6171A>T	p.E2057D	Substitution - Missense	Lung
COSM1192348	c.124C>T	p.R42*	Substitution - Nonsense	Kidney
COSM5370944	c.5418C>T	p.D1806D	Substitution - coding silent	Skin
COSM4501230	c.5182C>T	p.P1728S	Substitution - Missense	Skin
COSM4693847	c.1073C>G	p.S358*	Substitution - Nonsense	Large_intestine
COSM245106	c.3647C>A	p.S1216*	Substitution - Nonsense	Prostate
COSM4971822	c.822G>T	p.L274F	Substitution - Missense	Central_nervous_system
COSM1603627	c.1000T>G	p.F334V	Substitution - Missense	Liver
COSM2158625	c.66C>T	p.T22T	Substitution - coding silent	Large_intestine
COSM4015112	c.3523A>G	p.T1175A	Substitution - Missense	Stomach
COSM919513	c.612A>G	p.G204G	Substitution - coding silent	Endometrium
COSM919519	c.361A>C	p.N121H	Substitution - Missense	Endometrium
COSM1211271	c.4483T>C	p.S1495P	Substitution - Missense	Large_intestine
COSM684724	c.3005A>T	p.E1002V	Substitution - Missense	Lung
COSM1348577	c.5364delA	p.E1789fs*45	Deletion - Frameshift	Bone
COSM919463	c.4920C>T	p.V1640V	Substitution - coding silent	Endometrium
COSM3439585	c.2368C>T	p.Q790*	Substitution - Nonsense	Skin
COSM5421727	c.6596G>A	p.R2199H	Substitution - Missense	Prostate
COSM1348579	c.5357A>G	p.E1786G	Substitution - Missense	Large_intestine
COSM4805496	c.6686A>G	p.H2229R	Substitution - Missense	Liver
COSM1348577	c.5364delA	p.E1789fs*45	Deletion - Frameshift	Stomach
COSM1348577	c.5364delA	p.E1789fs*45	Deletion - Frameshift	Large_intestine
COSM2158617	c.178C>T	p.R60C	Substitution - Missense	Central_nervous_system
COSM427758	c.1189C>T	p.R397*	Substitution - Nonsense	Breast
COSM4550626	c.4401G>A	p.L1467L	Substitution - coding silent	Skin
COSM1128024	c.6894G>C	p.E2298D	Substitution - Missense	Prostate
COSM4015104	c.4773T>C	p.G1591G	Substitution - coding silent	Stomach
COSM684728	c.3338G>C	p.R1113T	Substitution - Missense	Lung
COSM302446	c.2830A>G	p.I944V	Substitution - Missense	Central_nervous_system
COSM5616476	c.6189C>T	p.A2063A	Substitution - coding silent	Lung
COSM4795043	c.5802G>A	p.K1934K	Substitution - coding silent	Liver
COSM919509	c.787G>A	p.E263K	Substitution - Missense	Endometrium
COSM1745838	c.4027G>A	p.D1343N	Substitution - Missense	Urinary_tract
COSM4144781	c.5712A>T	p.E1904D	Substitution - Missense	Thyroid
COSM4829447	c.5205+1G>C	p.?	Unknown	Cervix
COSM5483477	c.2697C>T	p.Y899Y	Substitution - coding silent	Large_intestine
COSM2158575	c.1020_1021insA	p.D341fs*3	Insertion - Frameshift	Large_intestine
COSM150849	c.2816_2821delGTTTAG	p.G939_L940delGL	Deletion - In frame	Pancreas
COSM5370948	c.3835A>G	p.N1279D	Substitution - Missense	Skin
COSM5510434	c.289G>A	p.G97S	Substitution - Missense	Biliary_tract
COSM5621066	c.5000A>G	p.Y1667C	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4803668	c.4143T>C	p.S1381S	Substitution - coding silent	Liver
COSM2158589	c.679G>A	p.A227T	Substitution - Missense	Lung
COSM5940039	c.5606C>T	p.P1869L	Substitution - Missense	Skin
COSM3439573	c.5653C>T	p.P1885S	Substitution - Missense	Skin
COSM3981068	c.3481G>C	p.V1161L	Substitution - Missense	Ovary
COSM71234	c.6584A>G	p.N2195S	Substitution - Missense	Ovary
COSM919467	c.4729G>A	p.E1577K	Substitution - Missense	Endometrium
COSM4413600	c.1980_1981TT>GC	p.S661P	Substitution - Missense	Genital_tract
COSM919521	c.284G>A	p.R95K	Substitution - Missense	Endometrium
COSM3439583	c.2443C>T	p.P815S	Substitution - Missense	Skin
COSM1211269	c.6214C>T	p.R2072C	Substitution - Missense	Large_intestine
COSM399610	c.2173C>G	p.P725A	Substitution - Missense	Lung
COSM1297351	c.3031C>A	p.P1011T	Substitution - Missense	Urinary_tract
COSM3935122	c.3965C>A	p.T1322K	Substitution - Missense	Oesophagus
COSM4015088	c.6273T>C	p.H2091H	Substitution - coding silent	Stomach
COSM1211267	c.3976A>C	p.N1326H	Substitution - Missense	Large_intestine
COSM3415167	c.5968G>T	p.D1990Y	Substitution - Missense	Large_intestine
COSM6013895	c.2558G>A	p.R853H	Substitution - Missense	Skin
COSM4790562	c.5162A>G	p.N1721S	Substitution - Missense	Liver
COSM3375505	c.1898C>T	p.A633V	Substitution - Missense	Pancreas
COSM304330	c.6784C>A	p.L2262I	Substitution - Missense	Large_intestine
COSM1135040	c.4987+2T>G	p.?	Unknown	Kidney
COSM2158413	c.4778A>C	p.K1593T	Substitution - Missense	Stomach
COSM2158499	c.2557C>T	p.R853C	Substitution - Missense	Lung
COSM3935120	c.4618C>T	p.R1540W	Substitution - Missense	Oesophagus
COSM5033627	c.6320A>G	p.N2107S	Substitution - Missense	Skin
COSM4620279	c.6879C>T	p.H2293H	Substitution - coding silent	Large_intestine
COSM4789700	c.3212A>T	p.H1071L	Substitution - Missense	Liver
COSM3382951	c.617A>G	p.E206G	Substitution - Missense	Pancreas
COSM919450	c.6361C>A	p.L2121I	Substitution - Missense	Endometrium
COSM3738678	c.4013G>T	p.R1338I	Substitution - Missense	Liver
COSM2158569	c.1043G>T	p.S348I	Substitution - Missense	Large_intestine
COSM919495	c.2147C>T	p.P716L	Substitution - Missense	Endometrium
COSM1297353	c.2422C>T	p.Q808*	Substitution - Nonsense	Urinary_tract
COSM2158569	c.1043G>T	p.S348I	Substitution - Missense	Large_intestine
COSM5496565	c.2470G>A	p.E824K	Substitution - Missense	Biliary_tract
COSM2158503	c.2429G>C	p.S810T	Substitution - Missense	Large_intestine
COSM240280	c.4292A>G	p.Y1431C	Substitution - Missense	Endometrium
COSM123824	c.4444G>A	p.D1482N	Substitution - Missense	Upper_aerodigestive_tract
COSM684730	c.4517G>T	p.G1506V	Substitution - Missense	Lung
COSM5477276	c.4662C>A	p.F1554L	Substitution - Missense	Large_intestine
COSM465843	c.5497C>T	p.L1833L	Substitution - coding silent	Large_intestine
COSM5820859	c.5123A>G	p.Y1708C	Substitution - Missense	Liver
COSM146944	c.890C>G	p.T297S	Substitution - Missense	Stomach
COSM3985686	c.2053T>A	p.W685R	Substitution - Missense	Kidney
COSM5359843	c.4476T>C	p.T1492T	Substitution - coding silent	Large_intestine
COSM465839	c.5866G>A	p.V1956M	Substitution - Missense	Kidney
COSM4897672	c.3115A>G	p.K1039E	Substitution - Missense	Skin
COSM5634461	c.5841A>G	p.E1947E	Substitution - coding silent	Oesophagus
COSM1242397	c.127C>T	p.R43C	Substitution - Missense	Large_intestine
COSM3709875	c.4987+1G>T	p.?	Unknown	Upper_aerodigestive_tract
COSM3807462	c.4887A>C	p.A1629A	Substitution - coding silent	Breast
COSM1348589	c.2873C>A	p.T958K	Substitution - Missense	Large_intestine
COSM1128024	c.6894G>C	p.E2298D	Substitution - Missense	Prostate
COSM465849	c.2126C>G	p.S709C	Substitution - Missense	Kidney
COSM5585507	c.1559C>T	p.P520L	Substitution - Missense	Skin
COSM5803946	c.5818A>T	p.S1940C	Substitution - Missense	Liver
COSM240280	c.4292A>G	p.Y1431C	Substitution - Missense	Prostate
COSM5800225	c.1945A>G	p.N649D	Substitution - Missense	Breast
COSM4179522	c.2818T>G	p.L940V	Substitution - Missense	Large_intestine
COSM1317446	c.3604T>C	p.S1202P	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM150849	c.2816_2821delGTTTAG	p.G939_L940delGL	Deletion - In frame	Stomach
COSM919499	c.1848G>T	p.Q616H	Substitution - Missense	Endometrium
COSM2158499	c.2557C>T	p.R853C	Substitution - Missense	Stomach
COSM5999043	c.419A>G	p.E140G	Substitution - Missense	Prostate
COSM4617033	c.128G>A	p.R43H	Substitution - Missense	Large_intestine
COSM1675286	c.2206A>G	p.K736E	Substitution - Missense	Large_intestine
COSM5753519	c.2539C>T	p.Q847*	Substitution - Nonsense	Large_intestine
COSM919487	c.3229G>A	p.G1077R	Substitution - Missense	Endometrium
COSM5967113	c.97A>G	p.K33E	Substitution - Missense	Pituitary
COSM321081	c.4471C>G	p.Q1491E	Substitution - Missense	Lung
COSM3807466	c.3850G>A	p.E1284K	Substitution - Missense	Breast
COSM1603629	c.686delA	p.K229fs*13	Deletion - Frameshift	Liver
COSM919511	c.735G>A	p.S245S	Substitution - coding silent	Endometrium
COSM3867595	c.1733C>T	p.P578L	Substitution - Missense	Skin
COSM1684209	c.2814_2819delAGGTTT	p.G939_L940delGL	Deletion - In frame	Haematopoietic_and_lymphoid_tissue
COSM4803668	c.4143T>C	p.S1381S	Substitution - coding silent	Liver
COSM223408	c.850C>T	p.P284S	Substitution - Missense	Skin
COSM919479	c.3999G>T	p.K1333N	Substitution - Missense	Endometrium
COSM128266	c.9T>C	p.V3V	Substitution - coding silent	Upper_aerodigestive_tract
COSM5753517	c.5356G>A	p.E1786K	Substitution - Missense	Large_intestine
COSM3665807	c.1022A>G	p.D341G	Substitution - Missense	Liver
COSM4015130	c.607G>A	p.A203T	Substitution - Missense	Stomach
COSM3395978	c.1934G>A	p.W645*	Substitution - Nonsense	Prostate

> Text Mining based Variations [ TOP ]
There is no record for JMJD1C.

Summary
Symbol	JMJD1C
Name	jumonji domain containing 1C
Aliases	DKFZp761F0118; KIAA1380; FLJ14374; TRIP8; thyroid hormone receptor interactor 8; TR-interacting protein 8; T ......
Location	10q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

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Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant
Q15652	320	S	Phosphoserine	-	No	None detected
Q15652	373	S	Phosphoserine	-	No	None detected
Q15652	376	S	Phosphoserine	-	No	None detected
Q15652	475	S	Phosphoserine	-	No	None detected
Q15652	501	S	Phosphoserine	-	No	None detected
Q15652	505	T	Phosphothreonine	-	No	None detected
Q15652	601	S	Phosphoserine	-	Yes	p.S601F (cancer: BLCA)
Q15652	617	S	Phosphoserine	-	No	None detected
Q15652	638	S	Phosphoserine	-	No	None detected
Q15652	639	S	Phosphoserine	-	No	None detected
Q15652	641	S	Phosphoserine	-	Yes	p.S641L (cancer: CESC)
Q15652	652	S	Phosphoserine	-	No	None detected
Q15652	943	S	Phosphoserine	-	No	None detected
Q15652	1989	S	Phosphoserine	-	No	None detected

Summary
Symbol	JMJD1C
Name	jumonji domain containing 1C
Aliases	DKFZp761F0118; KIAA1380; FLJ14374; TRIP8; thyroid hormone receptor interactor 8; TR-interacting protein 8; T ......
Location	10q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

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Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	6.127	5.3	-0.845	4.28e-06	Under
BRCA	Breast invasive carcinoma	112	1100	6.996	6.155	-0.84	4.7e-31	Under
CESC	Cervical and endocervical cancers	3	306	6.029	5.492	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	5.81	5.696	-0.208	0.0815	NS
ESCA	Esophageal carcinoma	11	185	6.929	6.634	-0.361	0.13	NS
GBM	Glioblastoma multiforme	5	166	5.974	5.358	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	5.897	5.517	-0.404	0.000669	NS
KIRC	Kidney renal clear cell carcinoma	72	534	6.398	6.301	-0.052	0.512	NS
KIRP	Kidney renal papillary cell carcinoma	32	291	6.1	5.96	-0.211	0.146	NS
LAML	Acute Myeloid Leukemia	0	173	NA	7.928	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	6.651	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	5.574	4.801	-0.733	6.28e-09	Under
LUAD	Lung adenocarcinoma	59	517	6.407	5.965	-0.458	3.49e-09	NS
LUSC	Lung squamous cell carcinoma	51	501	6.492	5.464	-1.078	4.98e-31	Under
OV	Ovarian serous cystadenocarcinoma	0	307	NA	5.459	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	6.495	6.22	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	5.648	5.815	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	6.119	6.016	-0.139	0.192	NS
READ	Rectum adenocarcinoma	10	167	5.841	5.572	-0.465	0.102	NS
SARC	Sarcoma	2	263	5.271	5.551	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	5.362	5.25	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	6.394	6.564	0.096	0.423	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	5.854	NA	NA	NA
THCA	Thyroid carcinoma	59	509	6.625	6.029	-0.579	2.96e-13	NS
THYM	Thymoma	2	120	6.225	5.591	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	6.334	5.285	-1.094	1.15e-14	Under

> Cancer Cell Line Encyclopedia (CCLE)

[ TOP ]

Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	7.7
Autonomic ganglia	CHP212	8.1
Autonomic ganglia	IMR32	8.2
Autonomic ganglia	KELLY	8.1
Autonomic ganglia	KPNRTBM1	8.4
Autonomic ganglia	KPNSI9S	7.3
Autonomic ganglia	KPNYN	8.6
Autonomic ganglia	MHHNB11	8.8
Autonomic ganglia	NB1	7.6
Autonomic ganglia	NH6	8.5
Autonomic ganglia	SHSY5Y	8.7
Autonomic ganglia	SIMA	7.8
Autonomic ganglia	SKNAS	7.5
Autonomic ganglia	SKNBE2	8.9
Autonomic ganglia	SKNDZ	8.1
Autonomic ganglia	SKNFI	7.9
Autonomic ganglia	SKNSH	7.6
Biliary tract	HUCCT1	7.8
Biliary tract	HUH28	7.3
Biliary tract	SNU1079	7.6
Biliary tract	SNU1196	7.5
Biliary tract	SNU245	7.5
Biliary tract	SNU308	7.3
Biliary tract	SNU478	7.9
Bone	143B	8.2
Bone	A673	7.9
Bone	CADOES1	7.5
Bone	CAL78	7.4
Bone	G292CLONEA141B1	7.5
Bone	HOS	8
Bone	HS706T	7.8
Bone	HS737T	7.5
Bone	HS819T	7.5
Bone	HS821T	7.5
Bone	HS822T	7.7
Bone	HS863T	7.4
Bone	HS870T	7.8
Bone	HS888T	7.8
Bone	MG63	7.4
Bone	MHHES1	8.2
Bone	OUMS27	8.3
Bone	RDES	8.7
Bone	SJSA1	8
Bone	SKES1	7.7
Bone	SKNMC	6.6
Bone	SW1353	7.7
Bone	T173	7.6
Bone	TC71	7.6
Bone	U2OS	8.1
Breast	AU565	7.2
Breast	BT20	7.2
Breast	BT474	7.8
Breast	BT483	6.9
Breast	BT549	7.1
Breast	CAL120	8
Breast	CAL148	7.1
Breast	CAL51	8.3
Breast	CAL851	7.3
Breast	CAMA1	7.2
Breast	DU4475	8.5
Breast	EFM192A	7
Breast	EFM19	7.3
Breast	EVSAT	6.8
Breast	HCC1143	8.9
Breast	HCC1187	8.5
Breast	HCC1395	7.5
Breast	HCC1419	7.3
Breast	HCC1428	7.8
Breast	HCC1500	7.2
Breast	HCC1569	6.5
Breast	HCC1599	8.5
Breast	HCC1806	8.3
Breast	HCC1937	6.8
Breast	HCC1954	7.3
Breast	HCC202	7.3
Breast	HCC2157	8
Breast	HCC2218	7.2
Breast	HCC38	8.3
Breast	HCC70	8.1
Breast	HDQP1	8.3
Breast	HMC18	8.6
Breast	HS274T	7.6
Breast	HS281T	7.5
Breast	HS343T	7.4
Breast	HS578T	6.8
Breast	HS606T	7.7
Breast	HS739T	7.6
Breast	HS742T	7.5
Breast	JIMT1	7.4
Breast	KPL1	7.4
Breast	MCF7	7.9
Breast	MDAMB134VI	7.2
Breast	MDAMB157	8
Breast	MDAMB175VII	7.1
Breast	MDAMB231	8.1
Breast	MDAMB361	7.1
Breast	MDAMB415	7.8
Breast	MDAMB436	7.7
Breast	MDAMB453	7.5
Breast	MDAMB468	7.6
Breast	SKBR3	7.5
Breast	T47D	8.1
Breast	UACC812	7.2
Breast	UACC893	7.5
Breast	YMB1	7.7
Breast	ZR751	7.7
Breast	ZR7530	7.8
Central nervous system	1321N1	7.3
Central nervous system	42MGBA	7.8
Central nervous system	8MGBA	7.8
Central nervous system	A172	7.5
Central nervous system	AM38	7.7
Central nervous system	BECKER	7.9
Central nervous system	CAS1	7.8
Central nervous system	CCFSTTG1	7.3
Central nervous system	D283MED	8.2
Central nervous system	D341MED	8.3
Central nervous system	DAOY	7.5
Central nervous system	DBTRG05MG	7.5
Central nervous system	DKMG	7.7
Central nervous system	GAMG	7.5
Central nervous system	GB1	7.2
Central nervous system	GI1	7.8
Central nervous system	GMS10	7.8
Central nervous system	GOS3	6.6
Central nervous system	H4	6.9
Central nervous system	HS683	7.2
Central nervous system	KALS1	7.5
Central nervous system	KG1C	7.8
Central nervous system	KNS42	6.4
Central nervous system	KNS60	8.2
Central nervous system	KNS81	6.7
Central nervous system	KS1	8.1
Central nervous system	LN18	7.4
Central nervous system	LN229	7.5
Central nervous system	M059K	7.3
Central nervous system	MOGGCCM	6.7
Central nervous system	MOGGUVW	7.7
Central nervous system	NMCG1	7.1
Central nervous system	ONS76	7.6
Central nervous system	SF126	7.7
Central nervous system	SF295	6.8
Central nervous system	SNB19	7.5
Central nervous system	SNU1105	7.4
Central nervous system	SNU201	6.6
Central nervous system	SNU466	6.7
Central nervous system	SNU489	6
Central nervous system	SNU626	6.6
Central nervous system	SNU738	6.8
Central nervous system	SW1088	7.3
Central nervous system	SW1783	7.4
Central nervous system	T98G	7.1
Central nervous system	TM31	8.4
Central nervous system	U118MG	7.1
Central nervous system	U138MG	6.6
Central nervous system	U251MG	7.5
Central nervous system	U87MG	7.4
Central nervous system	YH13	6.8
Central nervous system	YKG1	8.4
Endometrium	AN3CA	7.6
Endometrium	COLO684	7.7
Endometrium	EFE184	7.9
Endometrium	EN	7.7
Endometrium	ESS1	8.2
Endometrium	HEC108	8.9
Endometrium	HEC151	7.6
Endometrium	HEC1A	7.9
Endometrium	HEC1B	8
Endometrium	HEC251	8.2
Endometrium	HEC265	7.7
Endometrium	HEC50B	8.6
Endometrium	HEC59	8.9
Endometrium	HEC6	9
Endometrium	ISHIKAWAHERAKLIO02ER	7.5
Endometrium	JHUEM1	7.4
Endometrium	JHUEM2	7.8
Endometrium	JHUEM3	8.2
Endometrium	KLE	6.6
Endometrium	MFE280	7.5
Endometrium	MFE296	6.7
Endometrium	MFE319	7.7
Endometrium	RL952	7.7
Endometrium	SNGM	8.6
Endometrium	SNU1077	7.2
Endometrium	SNU685	7.3
Endometrium	TEN	7.8
Haematopoietic and lymphoid	697	8.1
Haematopoietic and lymphoid	A3KAW	7.6
Haematopoietic and lymphoid	A4FUK	7.2
Haematopoietic and lymphoid	ALLSIL	7.9
Haematopoietic and lymphoid	AML193	7.7
Haematopoietic and lymphoid	AMO1	6.9
Haematopoietic and lymphoid	BCP1	7.5
Haematopoietic and lymphoid	BDCM	8.5
Haematopoietic and lymphoid	BL41	8.6
Haematopoietic and lymphoid	BL70	8
Haematopoietic and lymphoid	BV173	8.4
Haematopoietic and lymphoid	CA46	9.6
Haematopoietic and lymphoid	CI1	8.2
Haematopoietic and lymphoid	CMK115	8.6
Haematopoietic and lymphoid	CMK86	8.2
Haematopoietic and lymphoid	CMK	8.1
Haematopoietic and lymphoid	CMLT1	7.9
Haematopoietic and lymphoid	COLO775	6.9
Haematopoietic and lymphoid	DAUDI	9.2
Haematopoietic and lymphoid	DB	8.5
Haematopoietic and lymphoid	DEL	8.1
Haematopoietic and lymphoid	DND41	7.3
Haematopoietic and lymphoid	DOHH2	8.5
Haematopoietic and lymphoid	EB1	8.8
Haematopoietic and lymphoid	EB2	8.5
Haematopoietic and lymphoid	EHEB	8.1
Haematopoietic and lymphoid	EJM	7.7
Haematopoietic and lymphoid	EM2	8.2
Haematopoietic and lymphoid	EOL1	8
Haematopoietic and lymphoid	F36P	8.1
Haematopoietic and lymphoid	GA10	8.6
Haematopoietic and lymphoid	GDM1	8.3
Haematopoietic and lymphoid	GRANTA519	8.9
Haematopoietic and lymphoid	HDLM2	7.2
Haematopoietic and lymphoid	HDMYZ	8.6
Haematopoietic and lymphoid	HEL9217	7.3
Haematopoietic and lymphoid	HEL	7.3
Haematopoietic and lymphoid	HH	8.2
Haematopoietic and lymphoid	HL60	7.9
Haematopoietic and lymphoid	HPBALL	7.9
Haematopoietic and lymphoid	HS604T	7
Haematopoietic and lymphoid	HS611T	8.3
Haematopoietic and lymphoid	HS616T	7.8
Haematopoietic and lymphoid	HS751T	7.5
Haematopoietic and lymphoid	HT	8.6
Haematopoietic and lymphoid	HTK	7.5
Haematopoietic and lymphoid	HUNS1	7.8
Haematopoietic and lymphoid	HUT102	8
Haematopoietic and lymphoid	HUT78	7.7
Haematopoietic and lymphoid	JEKO1	8.5
Haematopoietic and lymphoid	JK1	8.7
Haematopoietic and lymphoid	JM1	8.8
Haematopoietic and lymphoid	JURKAT	8
Haematopoietic and lymphoid	JURLMK1	8.2
Haematopoietic and lymphoid	JVM2	8.4
Haematopoietic and lymphoid	JVM3	8.3
Haematopoietic and lymphoid	K562	7.9
Haematopoietic and lymphoid	KARPAS299	7.5
Haematopoietic and lymphoid	KARPAS422	9.2
Haematopoietic and lymphoid	KARPAS620	8.1
Haematopoietic and lymphoid	KASUMI1	9.2
Haematopoietic and lymphoid	KASUMI2	8.4
Haematopoietic and lymphoid	KASUMI6	9
Haematopoietic and lymphoid	KCL22	7.7
Haematopoietic and lymphoid	KE37	7.8
Haematopoietic and lymphoid	KE97	8.2
Haematopoietic and lymphoid	KG1	8.8
Haematopoietic and lymphoid	KHM1B	7.6
Haematopoietic and lymphoid	KIJK	7.5
Haematopoietic and lymphoid	KMH2	6.9
Haematopoietic and lymphoid	KMM1	7.2
Haematopoietic and lymphoid	KMS11	8.1
Haematopoietic and lymphoid	KMS12BM	7.6
Haematopoietic and lymphoid	KMS18	8.3
Haematopoietic and lymphoid	KMS20	7.5
Haematopoietic and lymphoid	KMS21BM	7.1
Haematopoietic and lymphoid	KMS26	7.7
Haematopoietic and lymphoid	KMS27	7
Haematopoietic and lymphoid	KMS28BM	7.9
Haematopoietic and lymphoid	KMS34	8
Haematopoietic and lymphoid	KO52	8.1
Haematopoietic and lymphoid	KOPN8	8.3
Haematopoietic and lymphoid	KU812	7.8
Haematopoietic and lymphoid	KYO1	7.2
Haematopoietic and lymphoid	L1236	7
Haematopoietic and lymphoid	L363	8.7
Haematopoietic and lymphoid	L428	7
Haematopoietic and lymphoid	L540	7.1
Haematopoietic and lymphoid	LAMA84	8.1
Haematopoietic and lymphoid	LOUCY	8.8
Haematopoietic and lymphoid	LP1	8.5
Haematopoietic and lymphoid	M07E	8.2
Haematopoietic and lymphoid	MC116	7.7
Haematopoietic and lymphoid	ME1	7.2
Haematopoietic and lymphoid	MEC1	9
Haematopoietic and lymphoid	MEC2	7.4
Haematopoietic and lymphoid	MEG01	7
Haematopoietic and lymphoid	MHHCALL2	8.7
Haematopoietic and lymphoid	MHHCALL3	8.6
Haematopoietic and lymphoid	MHHCALL4	9.4
Haematopoietic and lymphoid	MINO	8.6
Haematopoietic and lymphoid	MJ	7.1
Haematopoietic and lymphoid	MM1S	7.7
Haematopoietic and lymphoid	MOLM13	9.2
Haematopoietic and lymphoid	MOLM16	8.3
Haematopoietic and lymphoid	MOLM6	8
Haematopoietic and lymphoid	MOLP2	7.2
Haematopoietic and lymphoid	MOLP8	7.1
Haematopoietic and lymphoid	MOLT13	8.2
Haematopoietic and lymphoid	MOLT16	7.9
Haematopoietic and lymphoid	MOLT4	7.9
Haematopoietic and lymphoid	MONOMAC1	9.9
Haematopoietic and lymphoid	MONOMAC6	9.4
Haematopoietic and lymphoid	MOTN1	7.2
Haematopoietic and lymphoid	MUTZ5	8.6
Haematopoietic and lymphoid	MV411	8.1
Haematopoietic and lymphoid	NALM19	9.2
Haematopoietic and lymphoid	NALM1	9.2
Haematopoietic and lymphoid	NALM6	8.4
Haematopoietic and lymphoid	NAMALWA	7.8
Haematopoietic and lymphoid	NB4	8
Haematopoietic and lymphoid	NCIH929	6.4
Haematopoietic and lymphoid	NCO2	9
Haematopoietic and lymphoid	NOMO1	9.3
Haematopoietic and lymphoid	NUDHL1	8.2
Haematopoietic and lymphoid	NUDUL1	8.8
Haematopoietic and lymphoid	OCIAML2	7.7
Haematopoietic and lymphoid	OCIAML3	7.1
Haematopoietic and lymphoid	OCIAML5	7.7
Haematopoietic and lymphoid	OCILY10	8.4
Haematopoietic and lymphoid	OCILY19	8.2
Haematopoietic and lymphoid	OCILY3	8.2
Haematopoietic and lymphoid	OCIM1	8.4
Haematopoietic and lymphoid	OPM2	8.2
Haematopoietic and lymphoid	P12ICHIKAWA	7.5
Haematopoietic and lymphoid	P31FUJ	7.7
Haematopoietic and lymphoid	P3HR1	8.1
Haematopoietic and lymphoid	PCM6	7
Haematopoietic and lymphoid	PEER	8.4
Haematopoietic and lymphoid	PF382	8.5
Haematopoietic and lymphoid	PFEIFFER	7.3
Haematopoietic and lymphoid	PL21	7.3
Haematopoietic and lymphoid	RAJI	8
Haematopoietic and lymphoid	RCHACV	7.9
Haematopoietic and lymphoid	REC1	9
Haematopoietic and lymphoid	REH	9.1
Haematopoietic and lymphoid	RI1	8
Haematopoietic and lymphoid	RL	7.6
Haematopoietic and lymphoid	RPMI8226	7.8
Haematopoietic and lymphoid	RPMI8402	7.8
Haematopoietic and lymphoid	RS411	9.2
Haematopoietic and lymphoid	SEM	10.2
Haematopoietic and lymphoid	SET2	8.4
Haematopoietic and lymphoid	SIGM5	7.5
Haematopoietic and lymphoid	SKM1	8.2
Haematopoietic and lymphoid	SKMM2	7.7
Haematopoietic and lymphoid	SR786	8.2
Haematopoietic and lymphoid	ST486	8.5
Haematopoietic and lymphoid	SUDHL10	7.4
Haematopoietic and lymphoid	SUDHL1	7.8
Haematopoietic and lymphoid	SUDHL4	7.5
Haematopoietic and lymphoid	SUDHL5	8.1
Haematopoietic and lymphoid	SUDHL6	8.6
Haematopoietic and lymphoid	SUDHL8	8.3
Haematopoietic and lymphoid	SUPB15	9
Haematopoietic and lymphoid	SUPHD1	7.3
Haematopoietic and lymphoid	SUPM2	7.6
Haematopoietic and lymphoid	SUPT11	6.8
Haematopoietic and lymphoid	SUPT1	8.4
Haematopoietic and lymphoid	TALL1	8.2
Haematopoietic and lymphoid	TF1	7.9
Haematopoietic and lymphoid	THP1	8.4
Haematopoietic and lymphoid	TO175T	7.7
Haematopoietic and lymphoid	TOLEDO	8.8
Haematopoietic and lymphoid	U266B1	8
Haematopoietic and lymphoid	U937	7.8
Haematopoietic and lymphoid	UT7	8.2
Haematopoietic and lymphoid	WSUDLCL2	8.1
Kidney	769P	8
Kidney	786O	7.6
Kidney	A498	7.4
Kidney	A704	7.4
Kidney	ACHN	8.6
Kidney	BFTC909	8
Kidney	CAKI1	8.4
Kidney	CAKI2	7.9
Kidney	CAL54	7.6
Kidney	KMRC1	7.8
Kidney	KMRC20	8.3
Kidney	KMRC2	7.4
Kidney	KMRC3	7.5
Kidney	OSRC2	7.6
Kidney	RCC10RGB	7.8
Kidney	SNU1272	7.7
Kidney	SNU349	7.2
Kidney	TUHR10TKB	6.9
Kidney	TUHR14TKB	7.7
Kidney	TUHR4TKB	7.2
Kidney	VMRCRCW	8.5
Kidney	VMRCRCZ	8.7
Large intestine	C2BBE1	8.3
Large intestine	CCK81	7.9
Large intestine	CL11	7.6
Large intestine	CL14	7.8
Large intestine	CL34	8
Large intestine	CL40	7
Large intestine	COLO205	7.7
Large intestine	COLO320	7.6
Large intestine	COLO678	7.9
Large intestine	CW2	6.9
Large intestine	DLD1	7.7
Large intestine	GP2D	7.9
Large intestine	HCC56	8.2
Large intestine	HCT116	8.1
Large intestine	HCT15	7.2
Large intestine	HS675T	7.5
Large intestine	HS698T	7.5
Large intestine	HT115	7.2
Large intestine	HT29	7.7
Large intestine	HT55	7.7
Large intestine	KM12	8.6
Large intestine	LOVO	7.6
Large intestine	LS1034	8.2
Large intestine	LS123	8.1
Large intestine	LS180	8.1
Large intestine	LS411N	8.1
Large intestine	LS513	7.6
Large intestine	MDST8	6.9
Large intestine	NCIH508	8
Large intestine	NCIH716	8
Large intestine	NCIH747	8.3
Large intestine	OUMS23	8.7
Large intestine	RCM1	8
Large intestine	RKO	8.9
Large intestine	SKCO1	7.7
Large intestine	SNU1040	7.5
Large intestine	SNU1197	7.5
Large intestine	SNU175	7.5
Large intestine	SNU283	7.3
Large intestine	SNU407	7.9
Large intestine	SNU503	6.7
Large intestine	SNU61	7.7
Large intestine	SNU81	7.9
Large intestine	SNUC1	6.6
Large intestine	SNUC2A	8.3
Large intestine	SNUC4	7.5
Large intestine	SNUC5	7.8
Large intestine	SW1116	8.6
Large intestine	SW1417	7.9
Large intestine	SW1463	7.8
Large intestine	SW403	7.9
Large intestine	SW480	7.5
Large intestine	SW48	7.7
Large intestine	SW620	8.6
Large intestine	SW837	7.9
Large intestine	SW948	7.7
Large intestine	T84	7.7
Liver	ALEXANDERCELLS	7.5
Liver	C3A	8.3
Liver	HEP3B217	7.7
Liver	HEPG2	8.1
Liver	HLE	7.6
Liver	HLF	6.7
Liver	HUH1	8.2
Liver	HUH6	7.8
Liver	HUH7	7.6
Liver	JHH1	7.1
Liver	JHH2	7.5
Liver	JHH4	8.1
Liver	JHH5	7.4
Liver	JHH6	8.3
Liver	JHH7	8
Liver	LI7	7.6
Liver	PLCPRF5	7.6
Liver	SKHEP1	8.1
Liver	SNU182	6.7
Liver	SNU387	7.1
Liver	SNU398	8.8
Liver	SNU423	7.7
Liver	SNU449	8.5
Liver	SNU475	7.6
Liver	SNU761	7.8
Liver	SNU878	7.6
Liver	SNU886	7.6
Lung	A549	7.7
Lung	ABC1	7.9
Lung	BEN	7.3
Lung	CAL12T	7.9
Lung	CALU1	7.5
Lung	CALU3	8.1
Lung	CALU6	8.2
Lung	CHAGOK1	7.5
Lung	COLO668	7.1
Lung	COLO699	7.4
Lung	CORL105	7.7
Lung	CORL23	7.8
Lung	CORL24	8
Lung	CORL279	7.8
Lung	CORL311	7.4
Lung	CORL47	8.1
Lung	CORL51	7.5
Lung	CORL88	7.2
Lung	CORL95	7.2
Lung	CPCN	7.9
Lung	DMS114	8.5
Lung	DMS153	8.4
Lung	DMS273	6.8
Lung	DMS454	7.3
Lung	DMS53	7.8
Lung	DMS79	8.6
Lung	DV90	6.9
Lung	EBC1	8.4
Lung	EPLC272H	7.8
Lung	HARA	7.4
Lung	HCC1171	7.2
Lung	HCC1195	7.2
Lung	HCC15	8.3
Lung	HCC2279	6.9
Lung	HCC2935	8.1
Lung	HCC33	7.2
Lung	HCC366	8.1
Lung	HCC4006	7.8
Lung	HCC44	7.6
Lung	HCC78	8.2
Lung	HCC827	7.6
Lung	HCC95	7
Lung	HLC1	7.4
Lung	HLFA	7.6
Lung	HS229T	7.8
Lung	HS618T	7.7
Lung	IALM	8.2
Lung	KNS62	7.6
Lung	LC1F	7.1
Lung	LC1SQSF	7.4
Lung	LCLC103H	8.1
Lung	LCLC97TM1	8.3
Lung	LK2	7.5
Lung	LOUNH91	7.5
Lung	LU65	7.9
Lung	LU99	8.4
Lung	LUDLU1	7.3
Lung	LXF289	8.2
Lung	MORCPR	7.1
Lung	NCIH1048	7.7
Lung	NCIH1092	8
Lung	NCIH1105	7.6
Lung	NCIH1155	7.8
Lung	NCIH1184	8.5
Lung	NCIH1299	7.2
Lung	NCIH1339	7
Lung	NCIH1341	7.4
Lung	NCIH1355	7.5
Lung	NCIH1373	8.4
Lung	NCIH1385	8.6
Lung	NCIH1395	7.2
Lung	NCIH1435	7.9
Lung	NCIH1436	7.7
Lung	NCIH1437	7.3
Lung	NCIH146	7.8
Lung	NCIH1563	6.9
Lung	NCIH1568	7
Lung	NCIH1573	8.4
Lung	NCIH1581	9
Lung	NCIH1618	8.2
Lung	NCIH1623	7.4
Lung	NCIH1648	7.7
Lung	NCIH1650	7.9
Lung	NCIH1651	7.5
Lung	NCIH1666	7.9
Lung	NCIH1693	8.1
Lung	NCIH1694	8.8
Lung	NCIH1703	8.3
Lung	NCIH1734	7.8
Lung	NCIH1755	8.2
Lung	NCIH1781	8.5
Lung	NCIH1792	7.3
Lung	NCIH1793	7.5
Lung	NCIH1836	8.1
Lung	NCIH1838	7.2
Lung	NCIH1869	7.6
Lung	NCIH1876	7.9
Lung	NCIH1915	9
Lung	NCIH1930	7
Lung	NCIH1944	7.5
Lung	NCIH1963	7.5
Lung	NCIH196	8
Lung	NCIH1975	8.3
Lung	NCIH2009	7.7
Lung	NCIH2023	7.8
Lung	NCIH2029	7.9
Lung	NCIH2030	8.2
Lung	NCIH2066	8.2
Lung	NCIH2081	7.7
Lung	NCIH2085	7.7
Lung	NCIH2087	8.2
Lung	NCIH209	7.8
Lung	NCIH2106	6.3
Lung	NCIH2110	7.9
Lung	NCIH211	7.9
Lung	NCIH2122	7.6
Lung	NCIH2126	7.5
Lung	NCIH2141	8
Lung	NCIH2170	7.1
Lung	NCIH2171	7.9
Lung	NCIH2172	7
Lung	NCIH2196	7.6
Lung	NCIH2227	7.5
Lung	NCIH2228	7.6
Lung	NCIH226	8.4
Lung	NCIH2286	7.4
Lung	NCIH2291	8.8
Lung	NCIH2342	7.9
Lung	NCIH2347	8.1
Lung	NCIH23	7.8
Lung	NCIH2405	7.9
Lung	NCIH2444	7.3
Lung	NCIH292	7.3
Lung	NCIH322	8
Lung	NCIH3255	7
Lung	NCIH358	6.9
Lung	NCIH441	8.1
Lung	NCIH446	7.9
Lung	NCIH460	7.4
Lung	NCIH510	7.8
Lung	NCIH520	7.8
Lung	NCIH522	8.2
Lung	NCIH524	6.8
Lung	NCIH526	6.5
Lung	NCIH596	7.3
Lung	NCIH647	7.9
Lung	NCIH650	7.7
Lung	NCIH661	8
Lung	NCIH69	7.8
Lung	NCIH727	7.5
Lung	NCIH810	7.9
Lung	NCIH82	7.3
Lung	NCIH838	8.8
Lung	NCIH841	7.8
Lung	NCIH854	8.1
Lung	NCIH889	8
Lung	PC14	8.1
Lung	RERFLCAD1	8.8
Lung	RERFLCAD2	8
Lung	RERFLCAI	7.6
Lung	RERFLCKJ	7.6
Lung	RERFLCMS	7.6
Lung	RERFLCSQ1	7.8
Lung	SBC5	8.3
Lung	SCLC21H	8.1
Lung	SHP77	6.9
Lung	SKLU1	7.2
Lung	SKMES1	7.6
Lung	SQ1	7.2
Lung	SW1271	8.1
Lung	SW1573	8.1
Lung	SW900	8
Lung	VMRCLCD	7.2
Lung	VMRCLCP	8
Oesophagus	COLO680N	7.8
Oesophagus	ECGI10	8
Oesophagus	KYSE140	8
Oesophagus	KYSE150	7.8
Oesophagus	KYSE180	7.2
Oesophagus	KYSE270	6.9
Oesophagus	KYSE30	8.2
Oesophagus	KYSE410	7.6
Oesophagus	KYSE450	8
Oesophagus	KYSE510	7.3
Oesophagus	KYSE520	8
Oesophagus	KYSE70	8.1
Oesophagus	OE19	6
Oesophagus	OE33	9.2
Oesophagus	TE10	7.5
Oesophagus	TE11	7.9
Oesophagus	TE14	7.7
Oesophagus	TE15	7.6
Oesophagus	TE1	8.7
Oesophagus	TE4	7.9
Oesophagus	TE5	8
Oesophagus	TE6	7.5
Oesophagus	TE8	10.8
Oesophagus	TE9	7.8
Oesophagus	TT	7.9
Ovary	59M	7.8
Ovary	A2780	8.9
Ovary	CAOV3	7.8
Ovary	CAOV4	7.7
Ovary	COLO704	8.4
Ovary	COV318	7.6
Ovary	COV362	7.8
Ovary	COV434	7.6
Ovary	COV504	7.7
Ovary	COV644	7.2
Ovary	EFO21	7.7
Ovary	EFO27	8.1
Ovary	ES2	8.3
Ovary	FUOV1	7.5
Ovary	HEYA8	9.3
Ovary	HS571T	7.5
Ovary	IGROV1	7.7
Ovary	JHOC5	7.5
Ovary	JHOM1	7.8
Ovary	JHOM2B	8.6
Ovary	JHOS2	8.1
Ovary	JHOS4	7.8
Ovary	KURAMOCHI	7.4
Ovary	MCAS	8.6
Ovary	NIHOVCAR3	7.6
Ovary	OAW28	7.3
Ovary	OAW42	6.8
Ovary	OC314	7.6
Ovary	OC316	7.8
Ovary	ONCODG1	8.2
Ovary	OV56	8
Ovary	OV7	7.3
Ovary	OV90	7.5
Ovary	OVCAR4	7.9
Ovary	OVCAR8	8.4
Ovary	OVISE	7.5
Ovary	OVK18	5.9
Ovary	OVKATE	9
Ovary	OVMANA	8
Ovary	OVSAHO	8.1
Ovary	OVTOKO	8
Ovary	RMGI	8.1
Ovary	RMUGS	6.3
Ovary	SKOV3	7.7
Ovary	SNU119	7.1
Ovary	SNU840	7.2
Ovary	SNU8	7.1
Ovary	TOV112D	7.8
Ovary	TOV21G	8.3
Ovary	TYKNU	8.1
Pancreas	ASPC1	9.2
Pancreas	BXPC3	6.9
Pancreas	CAPAN1	7.6
Pancreas	CAPAN2	8.6
Pancreas	CFPAC1	8.4
Pancreas	DANG	8.3
Pancreas	HPAC	8.7
Pancreas	HPAFII	7.5
Pancreas	HS766T	8.1
Pancreas	HUPT3	7.3
Pancreas	HUPT4	8.3
Pancreas	KCIMOH1	8.8
Pancreas	KLM1	5.7
Pancreas	KP2	8.6
Pancreas	KP3	8.3
Pancreas	KP4	9.2
Pancreas	L33	7.6
Pancreas	MIAPACA2	7.4
Pancreas	PANC0203	8.2
Pancreas	PANC0213	7.8
Pancreas	PANC0327	8
Pancreas	PANC0403	8
Pancreas	PANC0504	8.1
Pancreas	PANC0813	8.1
Pancreas	PANC1005	8.3
Pancreas	PANC1	8.8
Pancreas	PATU8902	7.7
Pancreas	PATU8988S	8.4
Pancreas	PATU8988T	7.6
Pancreas	PK1	8.3
Pancreas	PK45H	8.7
Pancreas	PK59	8.2
Pancreas	PL45	8.7
Pancreas	PSN1	7.4
Pancreas	QGP1	8.4
Pancreas	SNU213	8.3
Pancreas	SNU324	8
Pancreas	SNU410	7.6
Pancreas	SU8686	7.7
Pancreas	SUIT2	7.8
Pancreas	SW1990	8.5
Pancreas	T3M4	7.3
Pancreas	TCCPAN2	8.1
Pancreas	YAPC	7.8
Pleura	ACCMESO1	7.4
Pleura	DM3	6.7
Pleura	ISTMES1	7.9
Pleura	ISTMES2	8.4
Pleura	JL1	7.7
Pleura	MPP89	7.5
Pleura	MSTO211H	8.2
Pleura	NCIH2052	7.9
Pleura	NCIH2452	8.5
Pleura	NCIH28	8.2
Prostate	22RV1	7.4
Prostate	DU145	7.9
Prostate	LNCAPCLONEFGC	8.2
Prostate	MDAPCA2B	7.7
Prostate	NCIH660	8.6
Prostate	PC3	9
Prostate	VCAP	8.1
Salivary gland	A253	7.3
Salivary gland	YD15	8
Skin	A101D	7.5
Skin	A2058	7
Skin	A375	7.1
Skin	C32	7.4
Skin	CHL1	8.6
Skin	CJM	8.4
Skin	COLO679	7.2
Skin	COLO741	7.4
Skin	COLO783	6.9
Skin	COLO792	6.4
Skin	COLO800	7.4
Skin	COLO818	7.6
Skin	COLO829	7.8
Skin	COLO849	7.4
Skin	G361	7.3
Skin	GRM	6.6
Skin	HMCB	8.6
Skin	HS294T	6.7
Skin	HS600T	7.7
Skin	HS688AT	7.5
Skin	HS695T	7.9
Skin	HS839T	7.3
Skin	HS852T	7.7
Skin	HS895T	7.8
Skin	HS934T	7.3
Skin	HS936T	7.2
Skin	HS939T	7.3
Skin	HS940T	7.7
Skin	HS944T	6.6
Skin	HT144	7.4
Skin	IGR1	6.9
Skin	IGR37	6
Skin	IGR39	7.7
Skin	IPC298	8
Skin	K029AX	6.5
Skin	LOXIMVI	8.2
Skin	MALME3M	7.3
Skin	MDAMB435S	7.6
Skin	MELHO	7.2
Skin	MELJUSO	7.5
Skin	MEWO	7.6
Skin	RPMI7951	7.4
Skin	RVH421	7.3
Skin	SH4	7.7
Skin	SKMEL1	7.5
Skin	SKMEL24	7
Skin	SKMEL28	7.1
Skin	SKMEL2	7.6
Skin	SKMEL30	7.9
Skin	SKMEL31	7
Skin	SKMEL3	7
Skin	SKMEL5	6.7
Skin	UACC257	6.4
Skin	UACC62	7.1
Skin	WM115	7.4
Skin	WM1799	7.3
Skin	WM2664	7.5
Skin	WM793	7.6
Skin	WM88	7.2
Skin	WM983B	7.7
Small intestine	HUTU80	8.4
Soft tissue	A204	8.7
Soft tissue	G401	7.4
Soft tissue	G402	8.1
Soft tissue	GCT	8.1
Soft tissue	HS729	8
Soft tissue	HT1080	8
Soft tissue	KYM1	8
Soft tissue	MESSA	7.7
Soft tissue	RD	8.9
Soft tissue	RH30	8
Soft tissue	RH41	8.8
Soft tissue	RKN	9
Soft tissue	S117	7.9
Soft tissue	SJRH30	8
Soft tissue	SKLMS1	8.1
Soft tissue	SKUT1	8.4
Soft tissue	TE125T	7.9
Soft tissue	TE159T	7.2
Soft tissue	TE441T	6.3
Soft tissue	TE617T	8.4
Stomach	2313287	7.8
Stomach	AGS	8.1
Stomach	AZ521	7.7
Stomach	ECC10	8.5
Stomach	ECC12	8.1
Stomach	FU97	7.9
Stomach	GCIY	7.7
Stomach	GSS	8.2
Stomach	GSU	7.3
Stomach	HGC27	7.3
Stomach	HS746T	9.5
Stomach	HUG1N	7.9
Stomach	IM95	7.4
Stomach	KATOIII	7.4
Stomach	KE39	7.4
Stomach	LMSU	8
Stomach	MKN1	7.5
Stomach	MKN45	7.9
Stomach	MKN74	9.3
Stomach	MKN7	7.1
Stomach	NCCSTCK140	6.2
Stomach	NCIN87	7.9
Stomach	NUGC2	7.4
Stomach	NUGC3	7.4
Stomach	NUGC4	8.6
Stomach	OCUM1	7.7
Stomach	RERFGC1B	10.6
Stomach	SH10TC	7.4
Stomach	SNU16	7.6
Stomach	SNU1	7.9
Stomach	SNU216	8.7
Stomach	SNU520	7.1
Stomach	SNU5	7.2
Stomach	SNU601	7.1
Stomach	SNU620	7.4
Stomach	SNU668	7.9
Stomach	SNU719	7.3
Stomach	TGBC11TKB	8.3
Thyroid	8305C	7.3
Thyroid	8505C	7.9
Thyroid	BCPAP	7.3
Thyroid	BHT101	8.2
Thyroid	CAL62	8.7
Thyroid	CGTHW1	6.8
Thyroid	FTC133	6.7
Thyroid	FTC238	7.4
Thyroid	ML1	7.8
Thyroid	SW579	6.9
Thyroid	TT2609C02	7.6
Thyroid	TT	8.1
Upper aerodigestive tract	BHY	8.8
Upper aerodigestive tract	BICR16	6.4
Upper aerodigestive tract	BICR18	6.8
Upper aerodigestive tract	BICR22	8.1
Upper aerodigestive tract	BICR31	7.2
Upper aerodigestive tract	BICR56	8.6
Upper aerodigestive tract	BICR6	7.7
Upper aerodigestive tract	CAL27	8
Upper aerodigestive tract	CAL33	7.7
Upper aerodigestive tract	DETROIT562	7.5
Upper aerodigestive tract	FADU	7.8
Upper aerodigestive tract	HS840T	7.8
Upper aerodigestive tract	HSC2	7.6
Upper aerodigestive tract	HSC3	8.3
Upper aerodigestive tract	HSC4	8.3
Upper aerodigestive tract	PECAPJ15	7.6
Upper aerodigestive tract	PECAPJ34CLONEC12	7.4
Upper aerodigestive tract	PECAPJ41CLONED2	7.6
Upper aerodigestive tract	PECAPJ49	7.2
Upper aerodigestive tract	SCC15	7.7
Upper aerodigestive tract	SCC25	7.7
Upper aerodigestive tract	SCC4	7.9
Upper aerodigestive tract	SCC9	7.7
Upper aerodigestive tract	SNU1076	7.6
Upper aerodigestive tract	SNU1214	6.7
Upper aerodigestive tract	SNU46	8.1
Upper aerodigestive tract	SNU899	8.1
Upper aerodigestive tract	YD10B	8.3
Upper aerodigestive tract	YD38	8.3
Upper aerodigestive tract	YD8	8.2
Urinary tract	5637	7.4
Urinary tract	639V	7.7
Urinary tract	647V	7.1
Urinary tract	BC3C	7.3
Urinary tract	BFTC905	7.8
Urinary tract	CAL29	8
Urinary tract	HS172T	8.1
Urinary tract	HT1197	7.4
Urinary tract	HT1376	7.6
Urinary tract	J82	6.9
Urinary tract	JMSU1	8.2
Urinary tract	KMBC2	7.6
Urinary tract	KU1919	8
Urinary tract	RT11284	7.6
Urinary tract	RT112	7.4
Urinary tract	RT4	7.8
Urinary tract	SCABER	8.1
Urinary tract	SW1710	8.3
Urinary tract	SW780	7.7
Urinary tract	T24	7.7
Urinary tract	TCCSUP	7.1
Urinary tract	UMUC1	6.7
Urinary tract	UMUC3	8.4
Urinary tract	VMCUB1	8

> The Human Protein Atlas (HPA)

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Tissue	Expression Level (TPM)
Adipose tissue	17.5
Adrenal gland	15.7
Appendix	25.1
Bone marrow	23.5
Breast	25.6
Cerebral cortex	22
Cervix, uterine	29.1
Colon	10.9
Duodenum	16.9
Endometrium	37.9
Epididymis	13
Esophagus	13.6
Fallopian tube	19.6
Gallbladder	37.7
Heart muscle	7.7
Kidney	16
Liver	10.9
Lung	22.8
Lymph node	25.4
Ovary	28.6
Pancreas	2.6
Parathyroid gland	52.5
Placenta	19.3
Prostate	20.7
Rectum	13.2
Salivary gland	5.3
Seminal vesicle	15.1
Skeletal muscle	2.5
Skin	12.8
Small intestine	20.3
Smooth muscle	21.9
Spleen	28.1
Stomach	13
Testis	28
Thyroid gland	33
Tonsil	19.5
Urinary bladder	15.2

> Text Mining based Expression

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PMID	Expression	Cancer	Evidence
28123852	Overexpression	Oesophagal Squamous Cell Carcinoma	In this study, we demonstrated that JMJD1C was upregulated in patient EC tissues and different EC cell lines. Furthermore, JMJD1C levels were positively correlated with the TNM stage.

Summary
Symbol	JMJD1C
Name	jumonji domain containing 1C
Aliases	DKFZp761F0118; KIAA1380; FLJ14374; TRIP8; thyroid hormone receptor interactor 8; TR-interacting protein 8; T ......
Location	10q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

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Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.334	5.21e-12	35.1	52.7	12.1	Loss
BRCA	Breast invasive carcinoma	1075	0.323	1.75e-27	21.8	64.4	13.9	Neutral
CESC	Cervical and endocervical cancers	292	0.362	1.71e-10	25	68.2	6.8	Neutral
COAD	Colon adenocarcinoma	449	0.192	4.07e-05	19.8	74.2	6	Neutral
ESCA	Esophageal carcinoma	183	0.448	2e-10	27.3	51.9	20.8	Neutral
GBM	Glioblastoma multiforme	147	0.263	0.00128	90.5	8.8	0.7	Loss
HNSC	Head and Neck squamous cell carcinoma	514	0.28	9.91e-11	23.5	67.7	8.8	Neutral
KIRC	Kidney renal clear cell carcinoma	525	0.24	2.73e-08	17	80.8	2.3	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	0.181	0.00207	6.6	91	2.4	Neutral
LAML	Acute Myeloid Leukemia	166	0.182	0.0191	0.6	97.6	1.8	Neutral
LGG	Brain Lower Grade Glioma	513	0.45	6.51e-27	18.5	80.5	1	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.218	2.76e-05	21.4	67	11.5	Neutral
LUAD	Lung adenocarcinoma	512	0.438	1.83e-25	25.4	58	16.6	Neutral
LUSC	Lung squamous cell carcinoma	498	0.565	2.48e-43	44.2	43.8	12	Loss
OV	Ovarian serous cystadenocarcinoma	300	0.635	3.15e-35	28.3	49.3	22.3	Neutral
PAAD	Pancreatic adenocarcinoma	177	0.06	0.425	15.8	77.4	6.8	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	-0.039	0.619	1.2	93.2	5.6	Neutral
PRAD	Prostate adenocarcinoma	491	0.22	8.09e-07	12.2	83.1	4.7	Neutral
READ	Rectum adenocarcinoma	164	0.195	0.0123	25	72	3	Neutral
SARC	Sarcoma	255	0.351	8.38e-09	52.5	42.4	5.1	Loss
SKCM	Skin Cutaneous Melanoma	367	0.328	1.14e-10	60.5	38.7	0.8	Loss
STAD	Stomach adenocarcinoma	413	0.393	9.95e-17	18.4	63.2	18.4	Neutral
TGCT	Testicular Germ Cell Tumors	150	0.246	0.00238	52.7	42.7	4.7	Loss
THCA	Thyroid carcinoma	497	0.114	0.0112	2	97.6	0.4	Neutral
THYM	Thymoma	119	0.039	0.675	2.5	95.8	1.7	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.372	4.73e-19	9.1	68.2	22.7	Neutral

Summary
Symbol	JMJD1C
Name	jumonji domain containing 1C
Aliases	DKFZp761F0118; KIAA1380; FLJ14374; TRIP8; thyroid hormone receptor interactor 8; TR-interacting protein 8; T ......
Location	10q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

[ TOP ]

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.281	4.5e-09	17	408	0.028	0.32	NS/NA
BRCA	Breast invasive carcinoma	-0.314	1.9e-21	83	785	0.002	0.37	NS/NA
CESC	Cervical and endocervical cancers	-0.18	0.00147	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.144	0.0104	19	297	-0.001	0.177	NS/NA
ESCA	Esophageal carcinoma	-0.305	1.69e-05	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.241	0.0538	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.324	1.45e-14	20	522	0.018	4.62e-11	NS/NA
KIRC	Kidney renal clear cell carcinoma	-0.162	0.00268	24	319	0.028	6.78e-20	NS/NA
KIRP	Kidney renal papillary cell carcinoma	-0.26	5.64e-06	23	275	0.005	1.22e-06	NS/NA
LAML	Acute Myeloid Leukemia	-0.223	0.00355	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	-0.47	0	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.298	7.42e-10	41	373	0.1	1.78e-61	NS/NA
LUAD	Lung adenocarcinoma	-0.174	0.000137	21	456	0.039	0.149	NS/NA
LUSC	Lung squamous cell carcinoma	-0.267	1.59e-07	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	-0.75	0.0255	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.347	1.76e-06	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.202	0.00571	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.344	3.75e-16	35	498	0.065	5.47e-42	NS/NA
READ	Rectum adenocarcinoma	-0.105	0.294	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.312	2.67e-07	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.397	0	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.31	1.25e-09	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.21	0.00873	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.028	0.512	50	509	0	0.521	NS/NA
THYM	Thymoma	-0.012	0.898	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.126	0.00651	34	431	0.001	0.435	NS/NA

Summary
Symbol	JMJD1C
Name	jumonji domain containing 1C
Aliases	DKFZp761F0118; KIAA1380; FLJ14374; TRIP8; thyroid hormone receptor interactor 8; TR-interacting protein 8; T ......
Location	10q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Level	Level Name
Adrenal gland	2	Medium
Appendix	2	Medium
Bone marrow	1	Low
Breast	1	Low
Bronchus	2	Medium
Caudate	2	Medium
Cerebellum	2	Medium
Cerebral cortex	2	Medium
Cervix, uterine	2	Medium
Colon	2	Medium
Duodenum	2	Medium
Endometrium	2	Medium
Epididymis	2	Medium
Esophagus	2	Medium
Fallopian tube	2	Medium
Gallbladder	2	Medium
Heart muscle	1	Low
Hippocampus	1	Low
Kidney	2	Medium
Liver	2	Medium
Lung	2	Medium
Lymph node	2	Medium
Nasopharynx	2	Medium
Oral mucosa	2	Medium
Ovary	0	Not detected
Pancreas	2	Medium
Parathyroid gland	2	Medium
Placenta	2	Medium
Prostate	2	Medium
Rectum	2	Medium
Salivary gland	2	Medium
Seminal vesicle	1	Low
Skeletal muscle	1	Low
Skin	2	Medium
Small intestine	2	Medium
Smooth muscle	1	Low
Soft tissue	1	Low
Spleen	1	Low
Stomach	2	Medium
Testis	2	Medium
Thyroid gland	2	Medium
Tonsil	2	Medium
Urinary bladder	2	Medium
Vagina	2	Medium

Summary
Symbol	JMJD1C
Name	jumonji domain containing 1C
Aliases	DKFZp761F0118; KIAA1380; FLJ14374; TRIP8; thyroid hormone receptor interactor 8; TR-interacting protein 8; T ......
Location	10q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.0958	NS	24476821
BRCA	Breast invasive carcinoma	521	0.154	NS	23000897
COAD	Colon adenocarcinoma	149	0.59	NS	22810696
GBM	Glioblastoma multiforme	157	0.000578	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	3.05e-06	Significant	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.0685	NS	26536169
LGG	Brain Lower Grade Glioma	513	2.89e-27	Significant	26824661
LUAD	Lung adenocarcinoma	230	0.716	NS	25079552
LUSC	Lung squamous cell carcinoma	178	9.71e-07	Significant	22960745
OV	Ovarian serous cystadenocarcinoma	287	0.00098	Significant	21720365
PRAD	Prostate adenocarcinoma	333	4e-08	Significant	26544944
READ	Rectum adenocarcinoma	67	0.338	NS	22810696
SKCM	Skin Cutaneous Melanoma	315	0.00514	Significant	26091043
STAD	Stomach adenocarcinoma	277	0.236	NS	25079317
THCA	Thyroid carcinoma	391	0.478	NS	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	0.581	NS	23636398

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	1.184	0.421	NS
BRCA	Breast invasive carcinoma	1079	1.429	0.157	NS
CESC	Cervical and endocervical cancers	291	2.244	0.0237	Shorter
COAD	Colon adenocarcinoma	439	0.948	0.861	NS
ESCA	Esophageal carcinoma	184	0.908	0.779	NS
GBM	Glioblastoma multiforme	158	0.604	0.0552	NS
HNSC	Head and Neck squamous cell carcinoma	518	0.9	0.576	NS
KIRC	Kidney renal clear cell carcinoma	531	0.337	1.86e-06	Longer
KIRP	Kidney renal papillary cell carcinoma	287	1.087	0.844	NS
LAML	Acute Myeloid Leukemia	149	1.374	0.305	NS
LGG	Brain Lower Grade Glioma	511	0.432	0.000409	Longer
LIHC	Liver hepatocellular carcinoma	365	0.785	0.325	NS
LUAD	Lung adenocarcinoma	502	1.369	0.122	NS
LUSC	Lung squamous cell carcinoma	494	1.379	0.102	NS
OV	Ovarian serous cystadenocarcinoma	303	1.461	0.079	NS
PAAD	Pancreatic adenocarcinoma	177	1.954	0.0176	Shorter
PCPG	Pheochromocytoma and Paraganglioma	179	1670898442.979	0.0783	NS
PRAD	Prostate adenocarcinoma	497	0.555	0.628	NS
READ	Rectum adenocarcinoma	159	1.415	0.617	NS
SARC	Sarcoma	259	1.161	0.573	NS
SKCM	Skin Cutaneous Melanoma	459	0.572	0.00702	Longer
STAD	Stomach adenocarcinoma	388	0.842	0.457	NS
TGCT	Testicular Germ Cell Tumors	134	0.933	0.961	NS
THCA	Thyroid carcinoma	500	411855865.463	0.108	NS
THYM	Thymoma	119	1.913	0.449	NS
UCEC	Uterine Corpus Endometrial Carcinoma	543	1.197	0.566	NS

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	0.046	0.351	NS
BRCA	Breast invasive carcinoma	1071	-0.074	0.0148	Lower
CESC	Cervical and endocervical cancers	167	-0.044	0.568	NS
COAD	Colon adenocarcinoma	445	0	0.998	NS
ESCA	Esophageal carcinoma	162	-0.029	0.713	NS
HNSC	Head and Neck squamous cell carcinoma	448	0.059	0.211	NS
KIRC	Kidney renal clear cell carcinoma	531	-0.169	8.86e-05	Lower
KIRP	Kidney renal papillary cell carcinoma	260	-0.016	0.795	NS
LIHC	Liver hepatocellular carcinoma	347	0.003	0.961	NS
LUAD	Lung adenocarcinoma	507	0.036	0.419	NS
LUSC	Lung squamous cell carcinoma	497	0.033	0.458	NS
OV	Ovarian serous cystadenocarcinoma	302	0	0.994	NS
PAAD	Pancreatic adenocarcinoma	176	0.143	0.0576	NS
READ	Rectum adenocarcinoma	156	0.112	0.165	NS
SKCM	Skin Cutaneous Melanoma	410	-0.028	0.572	NS
STAD	Stomach adenocarcinoma	392	0.078	0.122	NS
TGCT	Testicular Germ Cell Tumors	81	0.01	0.931	NS
THCA	Thyroid carcinoma	499	-0.076	0.0918	NS
UCEC	Uterine Corpus Endometrial Carcinoma	501	0.043	0.339	NS

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	-0.058	0.339	NS
HNSC	Head and Neck squamous cell carcinoma	498	-0.006	0.89	NS
KIRC	Kidney renal clear cell carcinoma	525	-0.255	2.93e-09	Lower
LGG	Brain Lower Grade Glioma	514	-0.074	0.0956	NS
LIHC	Liver hepatocellular carcinoma	366	-0.068	0.194	NS
OV	Ovarian serous cystadenocarcinoma	296	-0.05	0.39	NS
PAAD	Pancreatic adenocarcinoma	176	0.007	0.926	NS
STAD	Stomach adenocarcinoma	406	0.077	0.12	NS
UCEC	Uterine Corpus Endometrial Carcinoma	534	0.043	0.326	NS

Summary
Symbol	JMJD1C
Name	jumonji domain containing 1C
Aliases	DKFZp761F0118; KIAA1380; FLJ14374; TRIP8; thyroid hormone receptor interactor 8; TR-interacting protein 8; T ......
Location	10q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	JMJD1C
Name	jumonji domain containing 1C
Aliases	DKFZp761F0118; KIAA1380; FLJ14374; TRIP8; thyroid hormone receptor interactor 8; TR-interacting protein 8; T ......
Location	10q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for JMJD1C.

Summary
Symbol	JMJD1C
Name	jumonji domain containing 1C
Aliases	DKFZp761F0118; KIAA1380; FLJ14374; TRIP8; thyroid hormone receptor interactor 8; TR-interacting protein 8; T ......
Location	10q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining

[ TOP ]

PMID	Cancer	Hierarchy	Gene	Relation to CR	Evidence
28123852	Oesophagal Squamous Cell Carcinoma	downstream	YAP1	regulation	Taken together, our results demonstrated that JMJD1C controls the proliferation of EC via modulation of H3K9me2 activity, targeting the YAP1 gene expression and functions as a tumor suppressor in EC.