CR2Cancer

Summary
Symbol	KAT6B
Name	lysine acetyltransferase 6B
Aliases	querkopf; qkf; Morf; MOZ2; ZC2HC6B; MOZ-related factor; MYST4; MYST histone acetyltransferase (monocytic leu ......
Location	10q22.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

[ TOP ]

Domain

PF01853 MOZ/SAS family
PF00628 PHD-finger

Function

Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2-dependent transcriptional activation. May be involved in cerebral cortex development. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.

Classification

Class	Modification	Substrate	Product	PubMed
Histone modification write	Histone acetylation	H3	H3ac	10497217

> Gene Ontology [ TOP ]
Biological Process	GO:0006323 DNA packaging GO:0006333 chromatin assembly or disassembly GO:0006334 nucleosome assembly GO:0006473 protein acetylation GO:0006475 internal protein amino acid acetylation GO:0016570 histone modification GO:0016573 histone acetylation GO:0018205 peptidyl-lysine modification GO:0018393 internal peptidyl-lysine acetylation GO:0018394 peptidyl-lysine acetylation GO:0031497 chromatin assembly GO:0034728 nucleosome organization GO:0043543 protein acylation GO:0043966 histone H3 acetylation GO:0065004 protein-DNA complex assembly GO:0071103 DNA conformation change GO:0071824 protein-DNA complex subunit organization
Molecular Function	GO:0004402 histone acetyltransferase activity GO:0008080 N-acetyltransferase activity GO:0008134 transcription factor binding GO:0016407 acetyltransferase activity GO:0016410 N-acyltransferase activity GO:0016746 transferase activity, transferring acyl groups GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups GO:0034212 peptide N-acetyltransferase activity GO:0061733 peptide-lysine-N-acetyltransferase activity
Cellular Component	GO:0000123 histone acetyltransferase complex GO:0000785 chromatin GO:0000786 nucleosome GO:0031248 protein acetyltransferase complex GO:0032993 protein-DNA complex GO:0044815 DNA packaging complex GO:0070775 H3 histone acetyltransferase complex GO:0070776 MOZ/MORF histone acetyltransferase complex GO:1902493 acetyltransferase complex

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	R-HSA-3247509: Chromatin modifying enzymes R-HSA-4839726: Chromatin organization R-HSA-3214847: HATs acetylate histones

Summary
Symbol	KAT6B
Name	lysine acetyltransferase 6B
Aliases	querkopf; qkf; Morf; MOZ2; ZC2HC6B; MOZ-related factor; MYST4; MYST histone acetyltransferase (monocytic leu ......
Location	10q22.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM1321196	c.4963G>C	p.V1655L	Substitution - Missense	Ovary
COSM3867844	c.5677C>T	p.P1893S	Substitution - Missense	Skin
COSM920519	c.474C>T	p.R158R	Substitution - coding silent	Endometrium
COSM5480796	c.2841G>A	p.M947I	Substitution - Missense	Large_intestine
COSM5946200	c.3933C>A	p.V1311V	Substitution - coding silent	Pancreas
COSM1675367	c.4574C>T	p.T1525I	Substitution - Missense	Large_intestine
COSM1965067	c.472C>T	p.R158C	Substitution - Missense	Large_intestine
COSM4015925	c.4878C>A	p.Y1626*	Substitution - Nonsense	Stomach
COSM1349142	c.5389C>T	p.R1797*	Substitution - Nonsense	Large_intestine
COSM4502885	c.625C>G	p.R209G	Substitution - Missense	Skin
COSM920527	c.1965C>T	p.D655D	Substitution - coding silent	Endometrium
COSM1603739	c.505G>A	p.G169R	Substitution - Missense	Liver
COSM1702652	c.307C>T	p.R103C	Substitution - Missense	Skin
COSM1638652	c.4374delT	p.L1460fs*1	Deletion - Frameshift	Stomach
COSM4015932	c.5640A>G	p.P1880P	Substitution - coding silent	Stomach
COSM3709952	c.2191C>G	p.Q731E	Substitution - Missense	Upper_aerodigestive_tract
COSM1216533	c.5360C>T	p.T1787M	Substitution - Missense	Large_intestine
COSM4964307	c.2829G>A	p.Q943Q	Substitution - coding silent	Pancreas
COSM4757755	c.3537A>C	p.E1179D	Substitution - Missense	Stomach
COSM212182	c.3761G>A	p.R1254H	Substitution - Missense	Endometrium
COSM1965177	c.5231C>T	p.P1744L	Substitution - Missense	Central_nervous_system
COSM5359945	c.236G>A	p.R79H	Substitution - Missense	Large_intestine
COSM5954182	c.4735G>A	p.D1579N	Substitution - Missense	Upper_aerodigestive_tract
COSM35785	c.4589G>A	p.G1530E	Substitution - Missense	Central_nervous_system
COSM1965083	c.1170A>G	p.A390A	Substitution - coding silent	Upper_aerodigestive_tract
COSM4492102	c.3910C>T	p.P1304S	Substitution - Missense	Skin
COSM685313	c.3329C>T	p.P1110L	Substitution - Missense	Lung
COSM4855950	c.2510G>T	p.C837F	Substitution - Missense	Cervix
COSM1627635	c.2373+3A>T	p.?	Unknown	Liver
COSM1675371	c.5966T>C	p.L1989P	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1638654	c.5856G>A	p.M1952I	Substitution - Missense	Stomach
COSM4776476	c.5646C>A	p.P1882P	Substitution - coding silent	Soft_tissue
COSM4913569	c.599T>C	p.L200P	Substitution - Missense	Liver
COSM4500465	c.5663C>T	p.P1888L	Substitution - Missense	Skin
COSM1965199	c.5967C>T	p.L1989L	Substitution - coding silent	Large_intestine
COSM4530258	c.1682G>A	p.G561E	Substitution - Missense	Skin
COSM1321197	c.4680G>T	p.Q1560H	Substitution - Missense	Ovary
COSM5020165	c.3235_3246del12	p.E1086_E1089delEEEE	Deletion - In frame	Soft_tissue
COSM5359945	c.236G>A	p.R79H	Substitution - Missense	Large_intestine
COSM3440613	c.4059G>A	p.E1353E	Substitution - coding silent	Skin
COSM1216532	c.4333C>T	p.P1445S	Substitution - Missense	Large_intestine
COSM5612048	c.5587C>G	p.Q1863E	Substitution - Missense	Adrenal_gland
COSM5922829	c.1550C>T	p.P517L	Substitution - Missense	Skin
COSM5050342	c.1894C>T	p.L632L	Substitution - coding silent	Stomach
COSM240807	c.323_337del15	p.N108_R112delNKLLR	Deletion - In frame	Prostate
COSM4801124	c.5830T>A	p.Y1944N	Substitution - Missense	Liver
COSM289833	c.4779G>A	p.Q1593Q	Substitution - coding silent	Large_intestine
COSM4852474	c.3028C>T	p.R1010W	Substitution - Missense	Cervix
COSM71774	c.3581A>T	p.Q1194L	Substitution - Missense	Ovary
COSM219996	c.6129C>T	p.H2043H	Substitution - coding silent	Prostate
COSM1965091	c.1344T>C	p.G448G	Substitution - coding silent	Large_intestine
COSM3440605	c.1352C>T	p.S451L	Substitution - Missense	Skin
COSM1638653	c.5550C>T	p.S1850S	Substitution - coding silent	Stomach
COSM35408	c.3291A>G	p.E1097E	Substitution - coding silent	Central_nervous_system
COSM1965179	c.5242G>A	p.V1748I	Substitution - Missense	Large_intestine
COSM3440604	c.879A>G	p.R293R	Substitution - coding silent	Skin
COSM1675363	c.2833C>A	p.L945I	Substitution - Missense	Large_intestine
COSM35408	c.3291A>G	p.E1097E	Substitution - coding silent	Ovary
COSM118575	c.3153C>T	p.S1051S	Substitution - coding silent	Ovary
COSM4144867	c.5849T>G	p.V1950G	Substitution - Missense	Thyroid
COSM5578776	c.886C>T	p.H296Y	Substitution - Missense	Skin
COSM94802	c.3494A>C	p.E1165A	Substitution - Missense	Ovary
COSM1349118	c.1430A>G	p.H477R	Substitution - Missense	Large_intestine
COSM3981140	c.3803G>C	p.G1268A	Substitution - Missense	Ovary
COSM3867843	c.2472C>T	p.F824F	Substitution - coding silent	Skin
COSM1627634	c.2016C>T	p.I672I	Substitution - coding silent	Liver
COSM5430918	c.2465A>G	p.E822G	Substitution - Missense	Oesophagus
COSM920526	c.1890G>A	p.R630R	Substitution - coding silent	Endometrium
COSM3440616	c.5380T>C	p.L1794L	Substitution - coding silent	Skin
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Soft_tissue
COSM5623578	c.3372G>T	p.K1124N	Substitution - Missense	Oesophagus
COSM1965130	c.3243A>C	p.E1081D	Substitution - Missense	Large_intestine
COSM1675369	c.5917C>T	p.P1973S	Substitution - Missense	Large_intestine
COSM1675364	c.3400G>T	p.G1134C	Substitution - Missense	Large_intestine
COSM1349120	c.2162C>A	p.S721Y	Substitution - Missense	Large_intestine
COSM920530	c.3139C>T	p.H1047Y	Substitution - Missense	Endometrium
COSM1965093	c.1365T>A	p.I455I	Substitution - coding silent	Upper_aerodigestive_tract
COSM4974517	c.4810C>T	p.H1604Y	Substitution - Missense	Oesophagus
COSM5371135	c.4850C>T	p.P1617L	Substitution - Missense	Skin
COSM1675369	c.5917C>T	p.P1973S	Substitution - Missense	Large_intestine
COSM5969913	c.3289_3294delGAAGAA	p.E1103_E1104delEE	Deletion - In frame	Upper_aerodigestive_tract
COSM35408	c.3291A>G	p.E1097E	Substitution - coding silent	Central_nervous_system
COSM4910544	c.3996T>C	p.P1332P	Substitution - coding silent	Liver
COSM685315	c.436C>A	p.P146T	Substitution - Missense	Lung
COSM1702655	c.2920T>A	p.C974S	Substitution - Missense	Skin
COSM1965093	c.1365T>A	p.I455I	Substitution - coding silent	Upper_aerodigestive_tract
COSM2157628	c.1200_1201insG	p.V401fs*26	Insertion - Frameshift	Central_nervous_system
COSM4757756	c.6146C>T	p.T2049M	Substitution - Missense	Stomach
COSM313088	c.3358G>T	p.A1120S	Substitution - Missense	Soft_tissue
COSM1506160	c.985G>C	p.E329Q	Substitution - Missense	Oesophagus
COSM5998930	c.606C>A	p.P202P	Substitution - coding silent	Prostate
COSM5570875	c.5907G>A	p.V1969V	Substitution - coding silent	Prostate
COSM1675372	c.6018C>A	p.Y2006*	Substitution - Nonsense	Kidney
COSM1579636	c.4203_4204delCT	p.S1402fs*5	Deletion - Frameshift	Central_nervous_system
COSM5999139	c.6200A>G	p.N2067S	Substitution - Missense	Prostate
COSM427939	c.2185G>A	p.E729K	Substitution - Missense	Breast
COSM4778198	c.4672A>C	p.T1558P	Substitution - Missense	Prostate
COSM1297443	c.406C>G	p.Q136E	Substitution - Missense	Urinary_tract
COSM35408	c.3291A>G	p.E1097E	Substitution - coding silent	Endometrium
COSM920542	c.6203G>A	p.G2068D	Substitution - Missense	Endometrium
COSM1675363	c.2833C>A	p.L945I	Substitution - Missense	Large_intestine
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Pancreas
COSM4854723	c.4855G>A	p.V1619I	Substitution - Missense	Cervix
COSM35408	c.3291A>G	p.E1097E	Substitution - coding silent	Central_nervous_system
COSM1216534	c.1028G>A	p.G343E	Substitution - Missense	Large_intestine
COSM162773	c.5041G>A	p.E1681K	Substitution - Missense	Stomach
COSM5711899	c.3603_3606delACAA	p.T1203fs*21	Deletion - Frameshift	Soft_tissue
COSM3867841	c.1034C>T	p.P345L	Substitution - Missense	Skin
COSM1965166	c.4688C>T	p.A1563V	Substitution - Missense	Large_intestine
COSM3440607	c.1557C>T	p.P519P	Substitution - coding silent	Skin
COSM4694065	c.3355G>A	p.V1119I	Substitution - Missense	Large_intestine
COSM5893473	c.1085C>T	p.S362F	Substitution - Missense	Skin
COSM5456039	c.1153T>C	p.S385P	Substitution - Missense	Large_intestine
COSM4015933	c.5809G>A	p.A1937T	Substitution - Missense	Stomach
COSM3686865	c.2612G>A	p.R871Q	Substitution - Missense	Large_intestine
COSM1349121	c.2376T>C	p.V792V	Substitution - coding silent	Large_intestine
COSM249537	c.2828A>T	p.Q943L	Substitution - Missense	Kidney
COSM465982	c.4750A>T	p.I1584F	Substitution - Missense	Kidney
COSM920534	c.4344C>A	p.S1448R	Substitution - Missense	Endometrium
COSM1965110	c.2235A>G	p.L745L	Substitution - coding silent	Large_intestine
COSM1187968	c.3763G>A	p.G1255S	Substitution - Missense	Lung
COSM4930687	c.3831A>T	p.P1277P	Substitution - coding silent	Liver
COSM5553704	c.2103A>C	p.E701D	Substitution - Missense	Prostate
COSM366029	c.3643A>T	p.K1215*	Substitution - Nonsense	Lung
COSM3397253	c.1663G>A	p.G555R	Substitution - Missense	Upper_aerodigestive_tract
COSM1965167	c.4807G>A	p.V1603I	Substitution - Missense	Stomach
COSM4015934	c.5869C>T	p.R1957W	Substitution - Missense	Large_intestine
COSM1191049	c.4944_4945insC	p.M1649fs*20	Insertion - Frameshift	Lung
COSM1349128	c.3279G>A	p.E1093E	Substitution - coding silent	Large_intestine
COSM231214	c.3488C>T	p.S1163L	Substitution - Missense	Skin
COSM4165548	c.1733C>A	p.S578Y	Substitution - Missense	Kidney
COSM5738956	c.280G>A	p.G94R	Substitution - Missense	Small_intestine
COSM5027252	c.2924C>T	p.S975F	Substitution - Missense	Breast
COSM920520	c.510G>A	p.P170P	Substitution - coding silent	Endometrium
COSM5548934	c.5512G>A	p.A1838T	Substitution - Missense	Prostate
COSM1739642	c.5192G>A	p.S1731N	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5020165	c.3235_3246del12	p.E1086_E1089delEEEE	Deletion - In frame	Skin
COSM4015921	c.4190C>T	p.T1397M	Substitution - Missense	Stomach
COSM1965082	c.1141T>A	p.C381S	Substitution - Missense	Upper_aerodigestive_tract
COSM5506330	c.55A>C	p.K19Q	Substitution - Missense	Biliary_tract
COSM5814465	c.4503A>T	p.E1501D	Substitution - Missense	Liver
COSM5039262	c.5963C>A	p.T1988N	Substitution - Missense	Liver
COSM5998931	c.5361G>A	p.T1787T	Substitution - coding silent	Prostate
COSM4803436	c.4294A>C	p.S1432R	Substitution - Missense	Liver
COSM5768989	c.5367C>T	p.N1789N	Substitution - coding silent	Breast
COSM4454780	c.5787A>G	p.S1929S	Substitution - coding silent	Skin
COSM35408	c.3291A>G	p.E1097E	Substitution - coding silent	Ovary
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Upper_aerodigestive_tract
COSM4542343	c.3168G>A	p.G1056G	Substitution - coding silent	Skin
COSM4469938	c.1629C>T	p.L543L	Substitution - coding silent	Skin
COSM143656	c.2684_2685CC>TT	p.S895F	Substitution - Missense	Skin
COSM219996	c.6129C>T	p.H2043H	Substitution - coding silent	Lung
COSM1603739	c.505G>A	p.G169R	Substitution - Missense	Liver
COSM3440609	c.2157C>T	p.Y719Y	Substitution - coding silent	Skin
COSM685314	c.2008A>G	p.I670V	Substitution - Missense	Lung
COSM5497974	c.4435G>A	p.V1479I	Substitution - Missense	Biliary_tract
COSM1965085	c.1215T>C	p.T405T	Substitution - coding silent	Upper_aerodigestive_tract
COSM6007628	c.5903G>A	p.S1968N	Substitution - Missense	Prostate
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Upper_aerodigestive_tract
COSM1603739	c.505G>A	p.G169R	Substitution - Missense	Liver
COSM1675365	c.3750A>C	p.K1250N	Substitution - Missense	Large_intestine
COSM1965113	c.2405delA	p.N803fs*5	Deletion - Frameshift	Large_intestine
COSM4842960	c.5841C>T	p.S1947S	Substitution - coding silent	Cervix
COSM394599	c.2022A>T	p.Q674H	Substitution - Missense	Lung
COSM212182	c.3761G>A	p.R1254H	Substitution - Missense	Stomach
COSM4015929	c.5045A>G	p.N1682S	Substitution - Missense	Stomach
COSM3383014	c.473G>A	p.R158H	Substitution - Missense	Pancreas
COSM4180817	c.1514C>T	p.P505L	Substitution - Missense	Large_intestine
COSM399613	c.1614C>T	p.S538S	Substitution - coding silent	Lung
COSM110520	c.4366C>T	p.Q1456*	Substitution - Nonsense	Skin
COSM1719609	c.4957C>T	p.P1653S	Substitution - Missense	Skin
COSM4494743	c.4397C>T	p.P1466L	Substitution - Missense	Skin
COSM3709952	c.2191C>G	p.Q731E	Substitution - Missense	Upper_aerodigestive_tract
COSM4015927	c.4906A>G	p.I1636V	Substitution - Missense	Stomach
COSM5999137	c.2738A>G	p.Y913C	Substitution - Missense	Prostate
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Upper_aerodigestive_tract
COSM4955352	c.6079A>T	p.M2027L	Substitution - Missense	Liver
COSM4591989	c.4063_4065delGAG	p.E1368delE	Deletion - In frame	Upper_aerodigestive_tract
COSM1965088	c.1246A>T	p.T416S	Substitution - Missense	Upper_aerodigestive_tract
COSM245911	c.2961G>A	p.W987*	Substitution - Nonsense	Prostate
COSM5616481	c.5871G>T	p.R1957R	Substitution - coding silent	Lung
COSM3440617	c.5576T>A	p.V1859D	Substitution - Missense	Skin
COSM3440608	c.2151C>T	p.G717G	Substitution - coding silent	Skin
COSM5371134	c.4504T>C	p.S1502P	Substitution - Missense	Skin
COSM3383015	c.3228G>C	p.E1076D	Substitution - Missense	Pancreas
COSM3440618	c.6052C>T	p.Q2018*	Substitution - Nonsense	Skin
COSM3981139	c.1715G>A	p.R572H	Substitution - Missense	Ovary
COSM1216530	c.1723A>G	p.T575A	Substitution - Missense	Large_intestine
COSM1745899	c.159C>G	p.L53L	Substitution - coding silent	Urinary_tract
COSM414948	c.2453A>G	p.Y818C	Substitution - Missense	Urinary_tract
COSM920536	c.5020G>A	p.E1674K	Substitution - Missense	Endometrium
COSM1638652	c.4374delT	p.L1460fs*1	Deletion - Frameshift	Breast
COSM3807736	c.4152T>G	p.G1384G	Substitution - coding silent	Breast
COSM4793490	c.3954G>T	p.L1318L	Substitution - coding silent	Liver
COSM1965081	c.1091A>G	p.N364S	Substitution - Missense	Upper_aerodigestive_tract
COSM138769	c.3154C>T	p.R1052W	Substitution - Missense	Skin
COSM5903752	c.635C>T	p.P212L	Substitution - Missense	Skin
COSM313088	c.3358G>T	p.A1120S	Substitution - Missense	Lung
COSM1965084	c.1180G>C	p.D394H	Substitution - Missense	Upper_aerodigestive_tract
COSM920535	c.4705T>G	p.C1569G	Substitution - Missense	Endometrium
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Upper_aerodigestive_tract
COSM1965163	c.4569C>T	p.V1523V	Substitution - coding silent	Large_intestine
COSM75542	c.4118A>G	p.E1373G	Substitution - Missense	Large_intestine
COSM1216528	c.2584C>T	p.P862S	Substitution - Missense	Large_intestine
COSM4015935	c.6210C>T	p.Y2070Y	Substitution - coding silent	Stomach
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Pancreas
COSM245912	c.6086G>T	p.G2029V	Substitution - Missense	Prostate
COSM5577519	c.265C>T	p.P89S	Substitution - Missense	Skin
COSM1317431	c.1800C>G	p.H600Q	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM272992	c.5789C>T	p.A1930V	Substitution - Missense	Large_intestine
COSM3440610	c.2682C>T	p.L894L	Substitution - coding silent	Skin
COSM3440611	c.3328C>T	p.P1110S	Substitution - Missense	Skin
COSM4015928	c.5011G>A	p.G1671S	Substitution - Missense	Stomach
COSM5492664	c.2914delA	p.T973fs*13	Deletion - Frameshift	Biliary_tract
COSM4639685	c.5486A>G	p.D1829G	Substitution - Missense	Large_intestine
COSM4500462	c.5662C>T	p.P1888S	Substitution - Missense	Skin
COSM1506159	c.1966G>A	p.G656R	Substitution - Missense	Prostate
COSM5998930	c.606C>A	p.P202P	Substitution - coding silent	Prostate
COSM370709	c.2054A>G	p.K685R	Substitution - Missense	Lung
COSM1675364	c.3400G>T	p.G1134C	Substitution - Missense	Lung
COSM3440614	c.4416G>A	p.E1472E	Substitution - coding silent	Skin
COSM3358949	c.4176A>G	p.E1392E	Substitution - coding silent	Kidney
COSM313089	c.5471C>G	p.T1824S	Substitution - Missense	Soft_tissue
COSM4694064	c.1010G>A	p.R337Q	Substitution - Missense	Large_intestine
COSM3415248	c.3449C>A	p.S1150*	Substitution - Nonsense	Large_intestine
COSM94800	c.2861G>T	p.R954I	Substitution - Missense	Prostate
COSM5562670	c.1689G>A	p.P563P	Substitution - coding silent	Prostate
COSM1745899	c.159C>G	p.L53L	Substitution - coding silent	Urinary_tract
COSM1675369	c.5917C>T	p.P1973S	Substitution - Missense	Large_intestine
COSM5576215	c.4622C>G	p.T1541S	Substitution - Missense	Stomach
COSM1349124	c.3252G>A	p.E1084E	Substitution - coding silent	Liver
COSM257480	c.3760C>T	p.R1254C	Substitution - Missense	Stomach
COSM305573	c.4764C>T	p.L1588L	Substitution - coding silent	Central_nervous_system
COSM4610732	c.4312G>A	p.E1438K	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM301382	c.2790G>A	p.A930A	Substitution - coding silent	Liver
COSM3440612	c.3489A>C	p.S1163S	Substitution - coding silent	Skin
COSM5422987	c.4156_4157insA	p.S1387fs*21	Insertion - Frameshift	Prostate
COSM1965064	c.104C>T	p.A35V	Substitution - Missense	Stomach
COSM3978794	c.5299G>T	p.A1767S	Substitution - Missense	Lung
COSM1470396	c.4379T>G	p.L1460*	Substitution - Nonsense	Prostate
COSM1965193	c.5878A>G	p.T1960A	Substitution - Missense	Large_intestine
COSM920531	c.3219G>A	p.E1073E	Substitution - coding silent	Endometrium
COSM1965157	c.4232A>G	p.E1411G	Substitution - Missense	Skin
COSM1675366	c.4470G>T	p.K1490N	Substitution - Missense	Large_intestine
COSM5826797	c.4077_4078insGAAGAGGAA	p.E1368_G1369insEEE	Insertion - In frame	Large_intestine
COSM5958100	c.5458C>A	p.L1820M	Substitution - Missense	Thyroid
COSM5789728	c.3219G>T	p.E1073D	Substitution - Missense	Breast
COSM301382	c.2790G>A	p.A930A	Substitution - coding silent	Liver
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Soft_tissue
COSM4169725	c.3844G>T	p.E1282*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM5440235	c.5582T>C	p.L1861P	Substitution - Missense	Oesophagus
COSM920533	c.4121G>A	p.G1374E	Substitution - Missense	Endometrium
COSM162773	c.5041G>A	p.E1681K	Substitution - Missense	Breast
COSM3807734	c.3961C>G	p.Q1321E	Substitution - Missense	Breast
COSM3807733	c.3216A>G	p.E1072E	Substitution - coding silent	Prostate
COSM1216535	c.3409C>T	p.R1137C	Substitution - Missense	Large_intestine
COSM920525	c.1786C>T	p.R596W	Substitution - Missense	Endometrium
COSM920529	c.2910G>A	p.K970K	Substitution - coding silent	Endometrium
COSM5575881	c.1355G>A	p.R452Q	Substitution - Missense	Stomach
COSM1675370	c.5965C>T	p.L1989F	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1675365	c.3750A>C	p.K1250N	Substitution - Missense	Large_intestine
COSM290684	c.2340A>C	p.E780D	Substitution - Missense	Large_intestine
COSM1171715	c.338G>A	p.R113K	Substitution - Missense	Oesophagus
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Upper_aerodigestive_tract
COSM4803436	c.4294A>C	p.S1432R	Substitution - Missense	Liver
COSM3985754	c.282G>T	p.G94G	Substitution - coding silent	Kidney
COSM1349117	c.1387C>T	p.R463C	Substitution - Missense	Large_intestine
COSM920521	c.1444G>T	p.G482C	Substitution - Missense	Endometrium
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Ovary
COSM5371133	c.371C>T	p.S124F	Substitution - Missense	Skin
COSM162774	c.4661A>G	p.E1554G	Substitution - Missense	Breast
COSM3731614	c.678T>A	p.N226K	Substitution - Missense	Stomach
COSM1258626	c.4858C>A	p.P1620T	Substitution - Missense	Oesophagus
COSM1675366	c.4470G>T	p.K1490N	Substitution - Missense	Large_intestine
COSM920525	c.1786C>T	p.R596W	Substitution - Missense	Breast
COSM427940	c.2623G>A	p.D875N	Substitution - Missense	Ovary
COSM4502406	c.6127C>T	p.H2043Y	Substitution - Missense	Skin
COSM4640994	c.1739C>T	p.T580M	Substitution - Missense	Large_intestine
COSM35408	c.3291A>G	p.E1097E	Substitution - coding silent	Central_nervous_system
COSM1965063	c.78G>A	p.R26R	Substitution - coding silent	Large_intestine
COSM3867842	c.1556C>T	p.P519L	Substitution - Missense	Skin
COSM4091212	c.2955G>A	p.L985L	Substitution - coding silent	Oesophagus
COSM3375539	c.1154C>T	p.S385L	Substitution - Missense	Pancreas
COSM301382	c.2790G>A	p.A930A	Substitution - coding silent	Large_intestine
COSM5576049	c.2143G>T	p.D715Y	Substitution - Missense	Stomach
COSM1965082	c.1141T>A	p.C381S	Substitution - Missense	Upper_aerodigestive_tract
COSM1965199	c.5967C>T	p.L1989L	Substitution - coding silent	Large_intestine
COSM3440603	c.622C>T	p.P208S	Substitution - Missense	Skin
COSM5027251	c.594C>T	p.V198V	Substitution - coding silent	Breast
COSM5905265	c.5252C>T	p.P1751L	Substitution - Missense	Skin
COSM35408	c.3291A>G	p.E1097E	Substitution - coding silent	Large_intestine
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Soft_tissue
COSM3440602	c.573C>T	p.F191F	Substitution - coding silent	Skin
COSM1349125	c.3258A>G	p.E1086E	Substitution - coding silent	Large_intestine
COSM5932630	c.5114C>T	p.S1705F	Substitution - Missense	Skin
COSM4938830	c.2243T>C	p.L748P	Substitution - Missense	Liver
COSM1965085	c.1215T>C	p.T405T	Substitution - coding silent	Upper_aerodigestive_tract
COSM1675365	c.3750A>C	p.K1250N	Substitution - Missense	Large_intestine
COSM3368124	c.461T>G	p.L154R	Substitution - Missense	Thyroid
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Upper_aerodigestive_tract
COSM3807731	c.1202T>G	p.V401G	Substitution - Missense	Breast
COSM4144868	c.5850A>G	p.V1950V	Substitution - coding silent	Thyroid
COSM1216529	c.2389A>G	p.S797G	Substitution - Missense	Large_intestine
COSM75542	c.4118A>G	p.E1373G	Substitution - Missense	Ovary
COSM1349119	c.2114A>G	p.E705G	Substitution - Missense	Upper_aerodigestive_tract
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Upper_aerodigestive_tract
COSM1965087	c.1238T>C	p.I413T	Substitution - Missense	Upper_aerodigestive_tract
COSM1965110	c.2235A>G	p.L745L	Substitution - coding silent	Large_intestine
COSM3375538	c.1056A>T	p.R352R	Substitution - coding silent	Pancreas
COSM5371136	c.5650C>T	p.L1884L	Substitution - coding silent	Skin
COSM1349115	c.566G>A	p.S189N	Substitution - Missense	Large_intestine
COSM1965115	c.2474delT	p.Y827fs*32	Deletion - Frameshift	Large_intestine
COSM32514	c.1447A>G	p.T483A	Substitution - Missense	Breast
COSM3375539	c.1154C>T	p.S385L	Substitution - Missense	Upper_aerodigestive_tract
COSM136790	c.4466C>T	p.P1489L	Substitution - Missense	Skin
COSM1965072	c.670G>T	p.E224*	Substitution - Nonsense	Large_intestine
COSM94798	c.1691G>C	p.S564T	Substitution - Missense	Lung
COSM5999292	c.1688C>T	p.P563L	Substitution - Missense	Prostate
COSM5942332	c.3752G>A	p.G1251E	Substitution - Missense	Skin
COSM4015934	c.5869C>T	p.R1957W	Substitution - Missense	Stomach
COSM4400304	c.4776A>C	p.Q1592H	Substitution - Missense	Skin
COSM3978793	c.2463C>A	p.V821V	Substitution - coding silent	Lung
COSM4015922	c.4311C>A	p.A1437A	Substitution - coding silent	Stomach
COSM3368125	c.2995G>C	p.E999Q	Substitution - Missense	Thyroid
COSM5564087	c.3173G>T	p.R1058L	Substitution - Missense	Prostate
COSM4437523	c.1547C>G	p.S516C	Substitution - Missense	Oesophagus
COSM1216527	c.94A>G	p.I32V	Substitution - Missense	Large_intestine
COSM4485794	c.2978C>T	p.S993F	Substitution - Missense	Skin
COSM1965099	c.1714C>T	p.R572C	Substitution - Missense	Stomach
COSM4641378	c.6111A>G	p.P2037P	Substitution - coding silent	Large_intestine
COSM920540	c.5836C>T	p.R1946C	Substitution - Missense	Endometrium
COSM4621890	c.2622T>C	p.I874I	Substitution - coding silent	Large_intestine
COSM1702656	c.6152C>T	p.P2051L	Substitution - Missense	Skin
COSM5613270	c.1072A>T	p.S358C	Substitution - Missense	Lung
COSM5024993	c.3251_3276>11	p.E1086_E1091>D	Complex - deletion inframe	Breast
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Upper_aerodigestive_tract
COSM4942829	c.5665A>G	p.M1889V	Substitution - Missense	Liver
COSM1603740	c.2264T>G	p.L755R	Substitution - Missense	Liver
COSM1702653	c.670G>A	p.E224K	Substitution - Missense	Skin
COSM3440606	c.1529C>T	p.S510F	Substitution - Missense	Skin
COSM257480	c.3760C>T	p.R1254C	Substitution - Missense	Large_intestine
COSM3985755	c.3050G>C	p.C1017S	Substitution - Missense	Kidney
COSM427940	c.2623G>A	p.D875N	Substitution - Missense	Breast
COSM1965088	c.1246A>T	p.T416S	Substitution - Missense	Upper_aerodigestive_tract
COSM427942	c.3916A>T	p.R1306W	Substitution - Missense	Breast
COSM920533	c.4121G>A	p.G1374E	Substitution - Missense	Large_intestine
COSM3440609	c.2157C>T	p.Y719Y	Substitution - coding silent	Skin
COSM5561517	c.3912C>G	p.P1304P	Substitution - coding silent	Prostate
COSM1965087	c.1238T>C	p.I413T	Substitution - Missense	Upper_aerodigestive_tract
COSM5552827	c.4236G>C	p.E1412D	Substitution - Missense	Prostate
COSM5029364	c.4351G>T	p.E1451*	Substitution - Nonsense	Bone
COSM4393344	c.1648A>T	p.I550F	Substitution - Missense	Prostate
COSM4488381	c.3319C>T	p.Q1107*	Substitution - Nonsense	Skin
COSM3440601	c.470A>C	p.K157T	Substitution - Missense	Skin
COSM1258625	c.510G>T	p.P170P	Substitution - coding silent	Stomach
COSM1702654	c.1687C>T	p.P563S	Substitution - Missense	Skin
COSM1216531	c.2789C>T	p.A930V	Substitution - Missense	Large_intestine
COSM42675	c.3949G>A	p.A1317T	Substitution - Missense	Central_nervous_system
COSM212182	c.3761G>A	p.R1254H	Substitution - Missense	Breast
COSM1965163	c.4569C>T	p.V1523V	Substitution - coding silent	Large_intestine
COSM4474693	c.1936C>T	p.P646S	Substitution - Missense	Skin
COSM4548755	c.4563G>A	p.K1521K	Substitution - coding silent	Skin
COSM1349126	c.3261G>T	p.E1087D	Substitution - Missense	Large_intestine
COSM5893473	c.1085C>T	p.S362F	Substitution - Missense	Skin
COSM4694066	c.4611C>T	p.I1537I	Substitution - coding silent	Large_intestine
COSM5575661	c.688A>G	p.K230E	Substitution - Missense	Stomach
COSM4801124	c.5830T>A	p.Y1944N	Substitution - Missense	Liver
COSM1349123	c.3208_3210delGAA	p.E1076delE	Deletion - In frame	Breast
COSM5962126	c.1394G>T	p.R465M	Substitution - Missense	Breast
COSM3867845	c.6028C>T	p.H2010Y	Substitution - Missense	Skin
COSM1675362	c.2397T>G	p.I799M	Substitution - Missense	Large_intestine
COSM5964185	c.1029A>G	p.G343G	Substitution - coding silent	Breast
COSM1216535	c.3409C>T	p.R1137C	Substitution - Missense	Large_intestine
COSM3730496	c.4632C>T	p.A1544A	Substitution - coding silent	Stomach
COSM1675372	c.6018C>A	p.Y2006*	Substitution - Nonsense	Lung
COSM1603740	c.2264T>G	p.L755R	Substitution - Missense	Liver
COSM5621073	c.2621T>C	p.I874T	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5999138	c.4422A>G	p.L1474L	Substitution - coding silent	Prostate
COSM1965092	c.1353A>C	p.S451S	Substitution - coding silent	Upper_aerodigestive_tract
COSM4015917	c.2467C>T	p.P823S	Substitution - Missense	Stomach
COSM920538	c.5511C>T	p.S1837S	Substitution - coding silent	Endometrium
COSM1965092	c.1353A>C	p.S451S	Substitution - coding silent	Upper_aerodigestive_tract
COSM1675371	c.5966T>C	p.L1989P	Substitution - Missense	Stomach
COSM3981141	c.5676G>A	p.P1892P	Substitution - coding silent	Ovary
COSM4955352	c.6079A>T	p.M2027L	Substitution - Missense	Liver
COSM313089	c.5471C>G	p.T1824S	Substitution - Missense	Lung
COSM3807733	c.3216A>G	p.E1072E	Substitution - coding silent	Breast
COSM75543	c.4853G>T	p.S1618I	Substitution - Missense	Ovary
COSM920539	c.5674C>T	p.P1892S	Substitution - Missense	Endometrium
COSM427944	c.4542G>A	p.K1514K	Substitution - coding silent	Breast
COSM1965067	c.472C>T	p.R158C	Substitution - Missense	Large_intestine
COSM94797	c.649A>G	p.S217G	Substitution - Missense	Lung
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Soft_tissue
COSM117940	c.6064C>T	p.Q2022*	Substitution - Nonsense	Ovary
COSM5999292	c.1688C>T	p.P563L	Substitution - Missense	Prostate
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Upper_aerodigestive_tract
COSM3807730	c.1131G>C	p.K377N	Substitution - Missense	Breast
COSM5969913	c.3289_3294delGAAGAA	p.E1103_E1104delEE	Deletion - In frame	Upper_aerodigestive_tract
COSM458787	c.4041C>T	p.L1347L	Substitution - coding silent	Cervix
COSM4793490	c.3954G>T	p.L1318L	Substitution - coding silent	Liver
COSM3807735	c.4051G>C	p.E1351Q	Substitution - Missense	Breast
COSM4435801	c.3134A>G	p.Y1045C	Substitution - Missense	Oesophagus
COSM1965153	c.3984A>G	p.E1328E	Substitution - coding silent	Large_intestine
COSM4694063	c.105G>A	p.A35A	Substitution - coding silent	Large_intestine
COSM5576079	c.1549C>G	p.P517A	Substitution - Missense	Stomach
COSM1675368	c.4904C>T	p.A1635V	Substitution - Missense	Large_intestine
COSM5749662	c.5992T>C	p.S1998P	Substitution - Missense	Genital_tract
COSM5005863	c.3275A>G	p.E1092G	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4015920	c.4080A>G	p.E1360E	Substitution - coding silent	Stomach
COSM1638654	c.5856G>A	p.M1952I	Substitution - Missense	Stomach
COSM5747142	c.5785T>A	p.S1929T	Substitution - Missense	Pancreas
COSM5999292	c.1688C>T	p.P563L	Substitution - Missense	Prostate
COSM920537	c.5117A>G	p.Y1706C	Substitution - Missense	Endometrium
COSM1745900	c.5010G>A	p.L1670L	Substitution - coding silent	Urinary_tract
COSM5019668	c.4078_4086delGAAGAGGAA	p.E1366_E1368delEEE	Deletion - In frame	Soft_tissue
COSM212182	c.3761G>A	p.R1254H	Substitution - Missense	Stomach
COSM3699938	c.815G>A	p.C272Y	Substitution - Missense	Liver
COSM1965088	c.1246A>T	p.T416S	Substitution - Missense	Upper_aerodigestive_tract
COSM1187969	c.4940G>C	p.S1647T	Substitution - Missense	Lung
COSM1684217	c.3929_3931delAGG	p.E1310delE	Deletion - In frame	Central_nervous_system
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Upper_aerodigestive_tract
COSM5767436	c.2642C>G	p.S881C	Substitution - Missense	Breast
COSM1474788	c.1786C>G	p.R596G	Substitution - Missense	Breast
COSM1187970	c.5411G>T	p.G1804V	Substitution - Missense	Lung
COSM5999139	c.6200A>G	p.N2067S	Substitution - Missense	Prostate
COSM1506159	c.1966G>A	p.G656R	Substitution - Missense	Prostate
COSM1965087	c.1238T>C	p.I413T	Substitution - Missense	Upper_aerodigestive_tract
COSM221761	c.2315G>A	p.G772E	Substitution - Missense	Skin
COSM1506159	c.1966G>A	p.G656R	Substitution - Missense	Prostate
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Breast
COSM4015919	c.3511C>T	p.Q1171*	Substitution - Nonsense	Stomach
COSM427938	c.801C>G	p.I267M	Substitution - Missense	Breast
COSM5020351	c.3717C>T	p.P1239P	Substitution - coding silent	Soft_tissue
COSM5655288	c.4812C>A	p.H1604Q	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4842090	c.4462G>C	p.E1488Q	Substitution - Missense	Cervix
COSM94799	c.1981G>T	p.D661Y	Substitution - Missense	Breast
COSM240809	c.4501G>T	p.E1501*	Substitution - Nonsense	Prostate
COSM1719609	c.4957C>T	p.P1653S	Substitution - Missense	Skin
COSM1349127	c.3270T>G	p.D1090E	Substitution - Missense	Large_intestine
COSM1349130	c.3288G>A	p.E1096E	Substitution - coding silent	Large_intestine
COSM4483707	c.2727C>T	p.V909V	Substitution - coding silent	Skin
COSM1745900	c.5010G>A	p.L1670L	Substitution - coding silent	Urinary_tract
COSM920541	c.6094C>T	p.P2032S	Substitution - Missense	Endometrium
COSM1675362	c.2397T>G	p.I799M	Substitution - Missense	Large_intestine
COSM1702653	c.670G>A	p.E224K	Substitution - Missense	Skin
COSM4919103	c.5282G>A	p.S1761N	Substitution - Missense	Liver
COSM5703707	c.4994G>A	p.S1665N	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM427943	c.4128A>G	p.G1376G	Substitution - coding silent	Breast
COSM3358948	c.3798G>C	p.K1266N	Substitution - Missense	Kidney
COSM240808	c.2629A>T	p.S877C	Substitution - Missense	Prostate
COSM4015930	c.5218A>C	p.I1740L	Substitution - Missense	Stomach
COSM427936	c.452G>A	p.R151Q	Substitution - Missense	Breast
COSM5613271	c.5070G>T	p.M1690I	Substitution - Missense	Lung
COSM75542	c.4118A>G	p.E1373G	Substitution - Missense	Large_intestine
COSM4015918	c.3502C>T	p.P1168S	Substitution - Missense	Stomach
COSM6013953	c.2116-5G>T	p.?	Unknown	Skin
COSM1965119	c.2753A>G	p.H918R	Substitution - Missense	Stomach
COSM5897751	c.4696C>T	p.Q1566*	Substitution - Nonsense	Skin
COSM1965092	c.1353A>C	p.S451S	Substitution - coding silent	Upper_aerodigestive_tract
COSM920532	c.3719A>G	p.E1240G	Substitution - Missense	Endometrium
COSM920520	c.510G>A	p.P170P	Substitution - coding silent	Stomach
COSM920524	c.1717C>T	p.R573C	Substitution - Missense	Endometrium
COSM4015931	c.5279C>T	p.P1760L	Substitution - Missense	Stomach
COSM1239541	c.235C>T	p.R79C	Substitution - Missense	Oesophagus
COSM414947	c.3244G>C	p.E1082Q	Substitution - Missense	Urinary_tract
COSM685312	c.5794C>A	p.L1932M	Substitution - Missense	Lung
COSM1965135	c.3288_3289insGAA	p.E1104_N1105insE	Insertion - In frame	Large_intestine
COSM4621891	c.4056A>T	p.E1352D	Substitution - Missense	Large_intestine
COSM1258627	c.451C>T	p.R151W	Substitution - Missense	Oesophagus
COSM920528	c.2068G>A	p.E690K	Substitution - Missense	Endometrium
COSM5812901	c.4726A>T	p.T1576S	Substitution - Missense	Liver
COSM111693	c.3289_3291delGAA	p.E1097delE	Deletion - In frame	Soft_tissue
COSM4015924	c.4862C>T	p.A1621V	Substitution - Missense	Stomach
COSM4015923	c.4857C>T	p.V1619V	Substitution - coding silent	Stomach
COSM920531	c.3219G>A	p.E1073E	Substitution - coding silent	Stomach
COSM1293296	c.1799A>G	p.H600R	Substitution - Missense	Cervix
COSM3440615	c.5369C>T	p.A1790V	Substitution - Missense	Skin
COSM283085	c.621+7G>A	p.?	Unknown	Large_intestine
COSM3807732	c.2106T>G	p.L702L	Substitution - coding silent	Breast
COSM5899014	c.5647A>T	p.N1883Y	Substitution - Missense	Skin
COSM1192967	c.3217_3218insG	p.E1073fs*19	Insertion - Frameshift	Lung
COSM3738727	c.1783A>C	p.S595R	Substitution - Missense	Liver
COSM465983	c.5771C>G	p.S1924C	Substitution - Missense	Kidney
COSM94801	c.3416G>C	p.R1139T	Substitution - Missense	Lung
COSM920522	c.1541_1543delCTT	p.S516delS	Deletion - In frame	Endometrium
COSM1675368	c.4904C>T	p.A1635V	Substitution - Missense	Large_intestine
COSM4884260	c.730G>T	p.G244*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM5922830	c.1549C>T	p.P517S	Substitution - Missense	Skin
COSM4015926	c.4878C>T	p.Y1626Y	Substitution - coding silent	Stomach
COSM4467690	c.1502C>T	p.S501F	Substitution - Missense	Skin
COSM1258628	c.362C>T	p.P121L	Substitution - Missense	Stomach
COSM3397253	c.1663G>A	p.G555R	Substitution - Missense	Central_nervous_system
COSM1349123	c.3208_3210delGAA	p.E1076delE	Deletion - In frame	Large_intestine
COSM245910	c.802G>T	p.E268*	Substitution - Nonsense	Prostate
COSM35719	c.4539G>A	p.Q1513Q	Substitution - coding silent	Central_nervous_system
COSM1675366	c.4470G>T	p.K1490N	Substitution - Missense	Large_intestine
COSM3981140	c.3803G>C	p.G1268A	Substitution - Missense	Ovary
COSM5941317	c.1123G>A	p.G375S	Substitution - Missense	Skin
COSM35718	c.2113G>A	p.E705K	Substitution - Missense	Central_nervous_system
COSM1675366	c.4470G>T	p.K1490N	Substitution - Missense	Large_intestine
COSM4611275	c.4098_4106delAGAGGAAGG	p.G1369_E1371delGEE	Deletion - In frame	Large_intestine
COSM1474789	c.6005T>A	p.M2002K	Substitution - Missense	Breast
COSM1675367	c.4574C>T	p.T1525I	Substitution - Missense	Large_intestine
COSM1965085	c.1215T>C	p.T405T	Substitution - coding silent	Upper_aerodigestive_tract
COSM235016	c.5671C>T	p.L1891L	Substitution - coding silent	Skin
COSM1179473	c.1520C>A	p.S507*	Substitution - Nonsense	Prostate
COSM920523	c.1635T>C	p.D545D	Substitution - coding silent	Endometrium
COSM5999138	c.4422A>G	p.L1474L	Substitution - coding silent	Prostate

> Text Mining based Variations

[ TOP ]

PMID	Variation	Cancer	Evidence
25920810	Mutation	Leukemia	The human KAT6A and KAT6B genes are recurrently mutated in leukemia, non-hematologic malignancies, and multiple developmental disorders displaying intellectual disability and various other abnormalities.
15147375	mutation	Acute Myeloid Leukemia	We report a novel fusion of the MYST4 and CBP genes in an acute myeloid leukaemia (AML)-M4 patient exhibiting t(10;16)(q22;p13) and t(11;17)(q23;q21). The t(10;16)(q22;p13) resulted in a rearrangement, where MYST4-CBP and CBP-MYST4 chimaeric transcripts were products of in-frame fusions of MYST4 exon 17 to CBP exon 6 and CBP exon 4 to MYST4 exon 18 respectively.
12619164	mutation	Acute Myeloid Leukemia	t(10;16)(q22;p13) and MORF-CREBBP fusion is a recurrent event in acute myeloid leukemia. Recently, it was shown that t(10;16)(q22;p13) fuses the MORF and CREBBP genes in a case of childhood acute myeloid leukemia (AML) M5a, with a complex karyotype containing other rearrangements.
11157802	mutation	Acute Myeloid Leukemia	RT-PCR using MORF forward and CBP reverse primers amplified a MORF-CBP fusion in which nucleotide 3103 of MORF was fused in-frame with nucleotide 284 of CBP. Nested RT-PCR with CBP forward and MORF reverse primers generated a CBP-MORF transcript in which nucleotide 283 of CBP was fused in-frame with nucleotide 3104 of MORF.

Summary
Symbol	KAT6B
Name	lysine acetyltransferase 6B
Aliases	querkopf; qkf; Morf; MOZ2; ZC2HC6B; MOZ-related factor; MYST4; MYST histone acetyltransferase (monocytic leu ......
Location	10q22.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

[ TOP ]

Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant
Q8WYB5	647	S	Phosphoserine	-	No	None detected
Q8WYB5	815	K	N6-acetyllysine	autocatalysis	No	None detected
Q8WYB5	1038	K	N6-acetyllysine	-	No	None detected
Q8WYB5	1042	K	N6-acetyllysine	-	No	None detected
Q8WYB5	1044	K	N6-acetyllysine	-	No	None detected
Q8WYB5	1048	S	Phosphoserine	-	No	None detected

Summary
Symbol	KAT6B
Name	lysine acetyltransferase 6B
Aliases	querkopf; qkf; Morf; MOZ2; ZC2HC6B; MOZ-related factor; MYST4; MYST histone acetyltransferase (monocytic leu ......
Location	10q22.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	5.593	4.582	-0.969	7.59e-07	Under
BRCA	Breast invasive carcinoma	112	1100	6.119	6.178	0.078	0.488	NS
CESC	Cervical and endocervical cancers	3	306	5.706	4.503	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	5.289	4.602	-0.667	9.52e-12	Under
ESCA	Esophageal carcinoma	11	185	6.731	5.736	-0.991	6.3e-08	Under
GBM	Glioblastoma multiforme	5	166	5.237	4.655	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	4.944	4.476	-0.425	0.00162	NS
KIRC	Kidney renal clear cell carcinoma	72	534	5.632	5.292	-0.38	4.44e-09	NS
KIRP	Kidney renal papillary cell carcinoma	32	291	5.416	4.667	-0.772	6.38e-10	Under
LAML	Acute Myeloid Leukemia	0	173	NA	7.208	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	6.141	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	3.796	3.405	-0.353	0.000849	NS
LUAD	Lung adenocarcinoma	59	517	5.655	4.961	-0.637	5.53e-13	Under
LUSC	Lung squamous cell carcinoma	51	501	5.53	5.1	-0.416	2.07e-05	NS
OV	Ovarian serous cystadenocarcinoma	0	307	NA	5.983	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	5.091	4.895	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	5.32	5.568	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	5.71	5.317	-0.404	5.6e-05	NS
READ	Rectum adenocarcinoma	10	167	5.326	4.503	-0.756	0.000478	Under
SARC	Sarcoma	2	263	4.707	4.759	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	4.053	4.452	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	6.146	5.725	-0.51	4.74e-05	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	5.702	NA	NA	NA
THCA	Thyroid carcinoma	59	509	5.96	5.857	-0.007	0.937	NS
THYM	Thymoma	2	120	6.195	5.273	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	5.925	5.302	-0.693	1.64e-07	Under

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	4.1
Adrenal gland	4.9
Appendix	4.1
Bone marrow	5
Breast	6.6
Cerebral cortex	7.4
Cervix, uterine	10.5
Colon	3.6
Duodenum	3.1
Endometrium	11.4
Epididymis	6.2
Esophagus	5.1
Fallopian tube	9.1
Gallbladder	5.8
Heart muscle	2.9
Kidney	4
Liver	1.3
Lung	6
Lymph node	4.9
Ovary	13
Pancreas	1.2
Parathyroid gland	17
Placenta	5.9
Prostate	7.1
Rectum	4.5
Salivary gland	2
Seminal vesicle	5.8
Skeletal muscle	2.5
Skin	4.2
Small intestine	3.9
Smooth muscle	8.7
Spleen	5.5
Stomach	4.8
Testis	11
Thyroid gland	9.5
Tonsil	3.8
Urinary bladder	4.3

> Text Mining based Expression

[ TOP ]

PMID	Expression	Cancer	Evidence
26208904	Loss of expression (copy number loss)	Small Cell Lung Cancer	Herein, we have identified the presence of homozygous deletions of the candidate histone acetyltransferase KAT6B, and the loss of the corresponding transcript, in SCLC cell lines and primary tumors.

Summary
Symbol	KAT6B
Name	lysine acetyltransferase 6B
Aliases	querkopf; qkf; Morf; MOZ2; ZC2HC6B; MOZ-related factor; MYST4; MYST histone acetyltransferase (monocytic leu ......
Location	10q22.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.357	1.28e-13	33.9	53.2	12.9	Loss
BRCA	Breast invasive carcinoma	1075	0.304	1.92e-24	21.2	63.3	15.4	Neutral
CESC	Cervical and endocervical cancers	292	0.39	4.77e-12	25.3	68.2	6.5	Neutral
COAD	Colon adenocarcinoma	449	0.344	6.3e-14	17.8	75.9	6.2	Neutral
ESCA	Esophageal carcinoma	183	0.452	1.28e-10	27.9	51.4	20.8	Neutral
GBM	Glioblastoma multiforme	147	0.16	0.053	90.5	9.5	0	Loss
HNSC	Head and Neck squamous cell carcinoma	514	0.215	8.64e-07	23.5	67.7	8.8	Neutral
KIRC	Kidney renal clear cell carcinoma	525	0.251	5.18e-09	17	80.6	2.5	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	0.237	4.86e-05	5.9	91	3.1	Neutral
LAML	Acute Myeloid Leukemia	166	0.183	0.0185	0.6	97.6	1.8	Neutral
LGG	Brain Lower Grade Glioma	513	0.549	1.05e-41	20.1	79.1	0.8	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.346	1.14e-11	22.5	66.2	11.3	Neutral
LUAD	Lung adenocarcinoma	512	0.411	2.91e-22	26.2	58	15.8	Neutral
LUSC	Lung squamous cell carcinoma	498	0.217	1.04e-06	45.6	42.4	12	Loss
OV	Ovarian serous cystadenocarcinoma	300	0.51	3.13e-21	24.3	45	30.7	Neutral
PAAD	Pancreatic adenocarcinoma	177	0.149	0.0481	15.3	76.8	7.9	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	0.195	0.0131	0.6	93.2	6.2	Neutral
PRAD	Prostate adenocarcinoma	491	0.302	7.74e-12	13.4	83.3	3.3	Neutral
READ	Rectum adenocarcinoma	164	0.264	0.000634	24.4	69.5	6.1	Neutral
SARC	Sarcoma	255	0.28	5.57e-06	53.7	41.6	4.7	Loss
SKCM	Skin Cutaneous Melanoma	367	0.426	1.18e-17	60.8	37.9	1.4	Loss
STAD	Stomach adenocarcinoma	413	0.594	1.12e-40	16.7	63.7	19.6	Neutral
TGCT	Testicular Germ Cell Tumors	150	0.361	5.54e-06	50.7	44	5.3	Loss
THCA	Thyroid carcinoma	497	0.163	0.000273	2.2	97.4	0.4	Neutral
THYM	Thymoma	119	0.084	0.361	2.5	95.8	1.7	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.533	8.82e-41	8.4	66.1	25.5	Neutral

Summary
Symbol	KAT6B
Name	lysine acetyltransferase 6B
Aliases	querkopf; qkf; Morf; MOZ2; ZC2HC6B; MOZ-related factor; MYST4; MYST histone acetyltransferase (monocytic leu ......
Location	10q22.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

[ TOP ]

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.437	0	17	408	0.041	0.723	NS/NA
BRCA	Breast invasive carcinoma	-0.574	0	83	785	-0.06	1.03e-25	NS/NA
CESC	Cervical and endocervical cancers	-0.253	7.22e-06	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.124	0.0273	19	297	-0.002	0.874	NS/NA
ESCA	Esophageal carcinoma	-0.184	0.0104	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.303	0.0146	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.229	8.11e-08	20	522	0	0.137	NS/NA
KIRC	Kidney renal clear cell carcinoma	-0.162	0.00265	24	319	0.009	3.67e-06	NS/NA
KIRP	Kidney renal papillary cell carcinoma	-0.278	1.18e-06	23	275	0.131	4.72e-17	NS/NA
LAML	Acute Myeloid Leukemia	-0.049	0.527	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	-0.297	4.05e-12	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.166	0.000713	41	373	0.002	0.00556	NS/NA
LUAD	Lung adenocarcinoma	-0.148	0.00116	21	456	0.053	0.000138	NS/NA
LUSC	Lung squamous cell carcinoma	-0.212	3.49e-05	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	-0.4	0.291	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.336	3.73e-06	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.454	9.44e-11	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.234	5.28e-08	35	498	-0.033	0.000767	NS/NA
READ	Rectum adenocarcinoma	-0.183	0.0678	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.243	6.94e-05	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.253	2.65e-08	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.321	3.08e-10	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.56	0	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.109	0.00992	50	509	-0.003	0.0843	NS/NA
THYM	Thymoma	-0.176	0.0532	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.287	3.65e-10	34	431	0.088	0.00394	NS/NA

Summary
Symbol	KAT6B
Name	lysine acetyltransferase 6B
Aliases	querkopf; qkf; Morf; MOZ2; ZC2HC6B; MOZ-related factor; MYST4; MYST histone acetyltransferase (monocytic leu ......
Location	10q22.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Level	Level Name
Adrenal gland	3	High
Appendix	3	High
Bone marrow	3	High
Breast	3	High
Bronchus	3	High
Caudate	3	High
Cerebellum	3	High
Cerebral cortex	3	High
Cervix, uterine	3	High
Colon	3	High
Duodenum	3	High
Endometrium	3	High
Epididymis	3	High
Esophagus	3	High
Fallopian tube	3	High
Gallbladder	3	High
Heart muscle	2	Medium
Hippocampus	3	High
Kidney	2	Medium
Liver	1	Low
Lung	3	High
Lymph node	2	Medium
Nasopharynx	3	High
Oral mucosa	3	High
Ovary	2	Medium
Pancreas	2	Medium
Parathyroid gland	2	Medium
Placenta	3	High
Prostate	3	High
Rectum	3	High
Salivary gland	3	High
Seminal vesicle	2	Medium
Skeletal muscle	2	Medium
Skin	3	High
Small intestine	3	High
Smooth muscle	1	Low
Soft tissue	3	High
Spleen	2	Medium
Stomach	3	High
Testis	3	High
Thyroid gland	3	High
Tonsil	3	High
Urinary bladder	3	High
Vagina	2	Medium

Summary
Symbol	KAT6B
Name	lysine acetyltransferase 6B
Aliases	querkopf; qkf; Morf; MOZ2; ZC2HC6B; MOZ-related factor; MYST4; MYST histone acetyltransferase (monocytic leu ......
Location	10q22.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.0044	Significant	24476821
BRCA	Breast invasive carcinoma	521	1.38e-37	Significant	23000897
COAD	Colon adenocarcinoma	149	0.136	NS	22810696
GBM	Glioblastoma multiforme	157	0.000627	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	3.77e-16	Significant	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.0571	NS	26536169
LGG	Brain Lower Grade Glioma	513	9.29e-35	Significant	26824661
LUAD	Lung adenocarcinoma	230	0.0136	Significant	25079552
LUSC	Lung squamous cell carcinoma	178	0.00132	Significant	22960745
OV	Ovarian serous cystadenocarcinoma	287	0.000185	Significant	21720365
PRAD	Prostate adenocarcinoma	333	0.022	Significant	26544944
READ	Rectum adenocarcinoma	67	0.363	NS	22810696
SKCM	Skin Cutaneous Melanoma	315	0.00182	Significant	26091043
STAD	Stomach adenocarcinoma	277	0.000457	Significant	25079317
THCA	Thyroid carcinoma	391	0.417	NS	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	0.00896	Significant	23636398

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	1.01	0.963	NS
BRCA	Breast invasive carcinoma	1079	1.063	0.787	NS
CESC	Cervical and endocervical cancers	291	1.127	0.705	NS
COAD	Colon adenocarcinoma	439	1.132	0.666	NS
ESCA	Esophageal carcinoma	184	0.984	0.957	NS
GBM	Glioblastoma multiforme	158	0.82	0.446	NS
HNSC	Head and Neck squamous cell carcinoma	518	0.581	0.007	Longer
KIRC	Kidney renal clear cell carcinoma	531	0.374	6.74e-05	Longer
KIRP	Kidney renal papillary cell carcinoma	287	1.123	0.8	NS
LAML	Acute Myeloid Leukemia	149	0.492	0.0177	Longer
LGG	Brain Lower Grade Glioma	511	0.331	8.62e-07	Longer
LIHC	Liver hepatocellular carcinoma	365	0.864	0.556	NS
LUAD	Lung adenocarcinoma	502	0.886	0.552	NS
LUSC	Lung squamous cell carcinoma	494	0.903	0.605	NS
OV	Ovarian serous cystadenocarcinoma	303	1.76	0.00852	Shorter
PAAD	Pancreatic adenocarcinoma	177	0.848	0.586	NS
PCPG	Pheochromocytoma and Paraganglioma	179	1.507	0.773	NS
PRAD	Prostate adenocarcinoma	497	0.542	0.607	NS
READ	Rectum adenocarcinoma	159	1.554	0.5	NS
SARC	Sarcoma	259	0.956	0.879	NS
SKCM	Skin Cutaneous Melanoma	459	0.769	0.204	NS
STAD	Stomach adenocarcinoma	388	1.145	0.551	NS
TGCT	Testicular Germ Cell Tumors	134	1.202	0.897	NS
THCA	Thyroid carcinoma	500	0.763	0.723	NS
THYM	Thymoma	119	0.229	0.153	NS
UCEC	Uterine Corpus Endometrial Carcinoma	543	1.2	0.525	NS

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	-0.096	0.0535	NS
BRCA	Breast invasive carcinoma	1071	-0.01	0.736	NS
CESC	Cervical and endocervical cancers	167	0.109	0.159	NS
COAD	Colon adenocarcinoma	445	-0.009	0.851	NS
ESCA	Esophageal carcinoma	162	-0.009	0.906	NS
HNSC	Head and Neck squamous cell carcinoma	448	0.001	0.986	NS
KIRC	Kidney renal clear cell carcinoma	531	-0.214	6.52e-07	Lower
KIRP	Kidney renal papillary cell carcinoma	260	0.12	0.0539	NS
LIHC	Liver hepatocellular carcinoma	347	0.033	0.54	NS
LUAD	Lung adenocarcinoma	507	0.067	0.135	NS
LUSC	Lung squamous cell carcinoma	497	0.054	0.231	NS
OV	Ovarian serous cystadenocarcinoma	302	-0.028	0.626	NS
PAAD	Pancreatic adenocarcinoma	176	-0.142	0.0598	NS
READ	Rectum adenocarcinoma	156	0.142	0.0765	NS
SKCM	Skin Cutaneous Melanoma	410	-0.019	0.706	NS
STAD	Stomach adenocarcinoma	392	0.095	0.061	NS
TGCT	Testicular Germ Cell Tumors	81	-0.311	0.00475	Lower
THCA	Thyroid carcinoma	499	-0.075	0.0931	NS
UCEC	Uterine Corpus Endometrial Carcinoma	501	-0.004	0.923	NS

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	-0.089	0.141	NS
HNSC	Head and Neck squamous cell carcinoma	498	0.096	0.0315	Higher
KIRC	Kidney renal clear cell carcinoma	525	-0.218	4.76e-07	Lower
LGG	Brain Lower Grade Glioma	514	-0.169	0.000123	Lower
LIHC	Liver hepatocellular carcinoma	366	-0.083	0.113	NS
OV	Ovarian serous cystadenocarcinoma	296	0.094	0.106	NS
PAAD	Pancreatic adenocarcinoma	176	-0.139	0.0667	NS
STAD	Stomach adenocarcinoma	406	0.12	0.0158	Higher
UCEC	Uterine Corpus Endometrial Carcinoma	534	-0.006	0.898	NS

Summary
Symbol	KAT6B
Name	lysine acetyltransferase 6B
Aliases	querkopf; qkf; Morf; MOZ2; ZC2HC6B; MOZ-related factor; MYST4; MYST histone acetyltransferase (monocytic leu ......
Location	10q22.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	KAT6B
Name	lysine acetyltransferase 6B
Aliases	querkopf; qkf; Morf; MOZ2; ZC2HC6B; MOZ-related factor; MYST4; MYST histone acetyltransferase (monocytic leu ......
Location	10q22.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for KAT6B.

Summary
Symbol	KAT6B
Name	lysine acetyltransferase 6B
Aliases	querkopf; qkf; Morf; MOZ2; ZC2HC6B; MOZ-related factor; MYST4; MYST histone acetyltransferase (monocytic leu ......
Location	10q22.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining [ TOP ]
There is no record for KAT6B.