Browse KDM3B in pancancer

Summary
SymbolKDM3B
Namelysine demethylase 3B
Aliases KIAA1082; NET22; C5orf7; JMJD1B; chromosome 5 open reading frame 7; jumonji domain containing 1B; 5qNCA; jmj ......
Location5q31.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Domain, Function and Classification
> Gene Ontology
> KEGG and Reactome Pathway
> Domain, Function and Classification
 
Domain PF02373 JmjC domain
Function

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.

Classification
Class Modification Substrate Product PubMed
Histone modification erase Histone methylation H3K9me1, H3K9me2 H3K9 16603237
> Gene Ontology
 
Biological Process GO:0006482 protein demethylation
GO:0008214 protein dealkylation
GO:0009636 response to toxic substance
GO:0016570 histone modification
GO:0016577 histone demethylation
GO:0033169 histone H3-K9 demethylation
GO:0070076 histone lysine demethylation
GO:0070988 demethylation
GO:0072718 response to cisplatin
GO:0098754 detoxification
GO:0098869 cellular oxidant detoxification
GO:1990267 response to transition metal nanoparticle
GO:1990748 cellular detoxification
Molecular Function GO:0003682 chromatin binding
GO:0016209 antioxidant activity
GO:0031490 chromatin DNA binding
GO:0032451 demethylase activity
GO:0032452 histone demethylase activity
GO:0032454 histone demethylase activity (H3-K9 specific)
GO:0043566 structure-specific DNA binding
GO:0051213 dioxygenase activity
Cellular Component GO:0000785 chromatin
> KEGG and Reactome Pathway
 
KEGG -
Reactome R-HSA-3247509: Chromatin modifying enzymes
R-HSA-4839726: Chromatin organization
R-HSA-3214842: HDMs demethylate histones
Summary
SymbolKDM3B
Namelysine demethylase 3B
Aliases KIAA1082; NET22; C5orf7; JMJD1B; chromosome 5 open reading frame 7; jumonji domain containing 1B; 5qNCA; jmj ......
Location5q31.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Mutation landscape in primary tumor tissue from TCGA
> Mutation landscape in cancer cell line from CCLE
> All mutations from COSMIC database V81
> Variations from text mining
> The Cancer Genome Atlas (TCGA)
 
> Cancer Cell Line Encyclopedia (CCLE)
 
There is no record.
> Catalogue of Somatic Mutations in Cancer (COSMIC)
 
COSMIC ID CDS change AA change Mutation Type Anatomical Site
COSM4818696c.2153C>Gp.S718CSubstitution - MissenseCervix
COSM3826845c.1189G>Cp.E397QSubstitution - MissenseBreast
COSM5907355c.2096C>Tp.S699FSubstitution - MissenseSkin
COSM5018255c.4684G>Tp.D1562YSubstitution - MissenseSoft_tissue
COSM3674287c.1127G>Tp.G376VSubstitution - MissenseProstate
COSM5402192c.2859C>Tp.L953LSubstitution - coding silentSkin
COSM1061367c.4731C>Tp.I1577ISubstitution - coding silentEndometrium
COSM5205940c.2137delGp.G714fs*81Deletion - FrameshiftBreast
COSM5684892c.4233A>Tp.Q1411HSubstitution - MissenseSoft_tissue
COSM3608978c.2054C>Tp.S685FSubstitution - MissenseSkin
COSM6011944c.3615G>Cp.L1205LSubstitution - coding silentSkin
COSM97867c.5051C>Tp.P1684LSubstitution - MissenseUpper_aerodigestive_tract
COSM3608988c.4402A>Tp.I1468FSubstitution - MissenseSkin
COSM4656989c.3265G>Ap.E1089KSubstitution - MissenseLarge_intestine
COSM3850427c.309C>Tp.D103DSubstitution - coding silentStomach
COSM1671901c.4330G>Tp.D1444YSubstitution - MissenseLarge_intestine
COSM1061379c.5143C>Tp.R1715CSubstitution - MissenseEndometrium
COSM1061365c.4483C>Tp.R1495*Substitution - NonsenseOesophagus
COSM3237287c.1260C>Tp.S420SSubstitution - coding silentOesophagus
COSM1061365c.4483C>Tp.R1495*Substitution - NonsenseEndometrium
COSM5776984c.3552T>Gp.T1184TSubstitution - coding silentBreast
COSM1061347c.3073C>Tp.R1025CSubstitution - MissenseEndometrium
COSM3608987c.4399G>Ap.E1467KSubstitution - MissenseSkin
COSM266753c.577C>Tp.R193*Substitution - NonsenseLarge_intestine
COSM4472153c.1763C>Tp.S588FSubstitution - MissenseSkin
COSM1433371c.1447T>Gp.L483VSubstitution - MissenseLarge_intestine
COSM4424791c.2821C>Tp.H941YSubstitution - MissenseOesophagus
COSM3826844c.1060A>Tp.I354FSubstitution - MissenseBreast
COSM4804748c.13G>Ap.A5TSubstitution - MissenseLiver
COSM3776204c.3202A>Gp.T1068ASubstitution - MissenseUrinary_tract
COSM1061365c.4483C>Tp.R1495*Substitution - NonsenseEndometrium
COSM4457377c.1042C>Tp.P348SSubstitution - MissenseSkin
COSM4977254c.564A>Tp.Q188HSubstitution - MissenseOesophagus
COSM1433383c.4212C>Ap.I1404ISubstitution - coding silentLarge_intestine
COSM4141429c.2699A>Gp.Q900RSubstitution - MissenseOvary
COSM3393158c.2776A>Gp.K926ESubstitution - MissensePancreas
COSM4382809c.3988G>Ap.A1330TSubstitution - MissenseLarge_intestine
COSM1753997c.1660C>Tp.R554WSubstitution - MissenseUrinary_tract
COSM5709467c.4240-1G>Tp.?UnknownHaematopoietic_and_lymphoid_tissue
COSM1719243c.1079C>Tp.T360ISubstitution - MissenseSkin
COSM1671898c.2743C>Tp.R915CSubstitution - MissenseLarge_intestine
COSM3237278c.942C>Tp.S314SSubstitution - coding silentUpper_aerodigestive_tract
COSM282115c.1789T>Ap.S597TSubstitution - MissenseLarge_intestine
COSM1173088c.5065C>Tp.H1689YSubstitution - MissenseOesophagus
COSM1061323c.1573T>Cp.L525LSubstitution - coding silentEndometrium
COSM390258c.2318C>Gp.S773*Substitution - NonsenseLung
COSM1061357c.3886C>Ap.L1296ISubstitution - MissenseEndometrium
COSM402664c.3194G>Ap.R1065HSubstitution - MissenseLung
COSM3237359c.5014G>Ap.A1672TSubstitution - MissenseUpper_aerodigestive_tract
COSM3661432c.3113T>Gp.L1038RSubstitution - MissenseLiver
COSM5427776c.5078A>Cp.N1693TSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM3608987c.4399G>Ap.E1467KSubstitution - MissenseLarge_intestine
COSM275659c.4398C>Tp.F1466FSubstitution - coding silentLarge_intestine
COSM1671900c.3899G>Tp.G1300VSubstitution - MissenseKidney
COSM5566534c.1838G>Ap.R613HSubstitution - MissenseProstate
COSM219514c.3340G>Ap.A1114TSubstitution - MissenseProstate
COSM245192c.2813G>Tp.R938LSubstitution - MissenseProstate
COSM3850438c.2792A>Gp.D931GSubstitution - MissenseStomach
COSM3850434c.778G>Ap.E260KSubstitution - MissenseStomach
COSM420407c.4346G>Tp.R1449MSubstitution - MissenseUrinary_tract
COSM4694941c.2337C>Tp.S779SSubstitution - coding silentLarge_intestine
COSM272844c.3118A>Gp.N1040DSubstitution - MissenseLarge_intestine
COSM3237309c.2070A>Gp.K690KSubstitution - coding silentLarge_intestine
COSM1567500c.1664delAp.D555fs*10Deletion - FrameshiftLarge_intestine
COSM5001365c.4549C>Tp.R1517*Substitution - NonsensePancreas
COSM5960387c.3950C>Tp.P1317LSubstitution - MissenseThyroid
COSM217332c.5025G>Tp.Q1675HSubstitution - MissenseLiver
COSM4953478c.5163G>Tp.R1721SSubstitution - MissenseLiver
COSM1753997c.1660C>Tp.R554WSubstitution - MissenseUrinary_tract
COSM4817373c.4515G>Cp.L1505LSubstitution - coding silentCervix
COSM351127c.1192G>Ap.V398MSubstitution - MissenseLung
COSM1061325c.1577T>Gp.F526CSubstitution - MissenseEndometrium
COSM1186839c.1794G>Cp.M598ISubstitution - MissenseLung
COSM5639812c.2051C>Ap.A684ESubstitution - MissenseOesophagus
COSM735554c.294G>Tp.W98CSubstitution - MissenseLung
COSM482000c.350G>Tp.W117LSubstitution - MissenseKidney
COSM5474768c.1251A>Gp.I417MSubstitution - MissenseLarge_intestine
COSM1495901c.3791C>Tp.A1264VSubstitution - MissenseKidney
COSM219514c.3340G>Ap.A1114TSubstitution - MissenseBreast
COSM312111c.1361G>Cp.R454PSubstitution - MissenseSoft_tissue
COSM5720373c.3621C>Tp.A1207ASubstitution - coding silentSkin
COSM1319282c.2813G>Ap.R938HSubstitution - MissenseStomach
COSM1173088c.5065C>Tp.H1689YSubstitution - MissenseLiver
COSM1637198c.910G>Ap.G304RSubstitution - MissenseBone
COSM4877529c.2606G>Ap.R869QSubstitution - MissenseProstate
COSM1211726c.2860C>Tp.R954CSubstitution - MissenseLarge_intestine
COSM40827c.237G>Ap.W79*Substitution - NonsenseCentral_nervous_system
COSM1061321c.1497G>Ap.E499ESubstitution - coding silentEndometrium
COSM3722258c.4414C>Tp.R1472*Substitution - NonsenseUpper_aerodigestive_tract
COSM3946874c.703G>Ap.E235KSubstitution - MissenseLarge_intestine
COSM5772390c.3308-7T>Ap.?UnknownBreast
COSM75104c.2623C>Ap.L875MSubstitution - MissenseOvary
COSM4440022c.3946delCp.P1317fs*10Deletion - FrameshiftThyroid
COSM735549c.2611C>Ap.R871RSubstitution - coding silentLung
COSM4818733c.2456C>Gp.S819*Substitution - NonsenseCervix
COSM1061339c.2301C>Tp.N767NSubstitution - coding silentEndometrium
COSM3608985c.3726C>Tp.S1242SSubstitution - coding silentSkin
COSM1061337c.2080A>Gp.I694VSubstitution - MissenseEndometrium
COSM3850439c.3188G>Ap.R1063QSubstitution - MissenseStomach
COSM482001c.4272C>Tp.L1424LSubstitution - coding silentKidney
COSM387584c.1667C>Tp.S556LSubstitution - MissenseLung
COSM291820c.277G>Ap.E93KSubstitution - MissenseLarge_intestine
COSM5043378c.2606G>Tp.R869LSubstitution - MissenseLiver
COSM1061319c.1458A>Gp.G486GSubstitution - coding silentEndometrium
COSM1211730c.3082C>Tp.R1028WSubstitution - MissenseLarge_intestine
COSM3237324c.2994_3001delCTGCCAGCp.C999fs*4Deletion - FrameshiftLarge_intestine
COSM1061309c.654T>Cp.V218VSubstitution - coding silentEndometrium
COSM3237278c.942C>Tp.S314SSubstitution - coding silentUpper_aerodigestive_tract
COSM1619532c.4934A>Tp.D1645VSubstitution - MissenseLiver
COSM5423377c.360+1_360+2insGGGTp.?UnknownProstate
COSM5060647c.1983T>Gp.S661SSubstitution - coding silentStomach
COSM3765162c.4503-1G>Ap.?UnknownCentral_nervous_system
COSM3826843c.1013G>Cp.R338TSubstitution - MissenseBreast
COSM4618463c.2495C>Tp.T832ISubstitution - MissenseLarge_intestine
COSM4961363c.2630-1G>Ap.?UnknownLiver
COSM1285699c.2493G>Ap.K831KSubstitution - coding silentAutonomic_ganglia
COSM4889826c.4190G>Tp.S1397ISubstitution - MissenseUpper_aerodigestive_tract
COSM282117c.4808T>Gp.I1603SSubstitution - MissenseLarge_intestine
COSM1671898c.2743C>Tp.R915CSubstitution - MissenseLarge_intestine
COSM4541733c.3059G>Ap.W1020*Substitution - NonsenseSkin
COSM1061311c.1228C>Ap.L410MSubstitution - MissenseEndometrium
COSM5491928c.3898G>Ap.G1300RSubstitution - MissenseBiliary_tract
COSM1173088c.5065C>Tp.H1689YSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM3428944c.1861C>Ap.L621ISubstitution - MissenseLarge_intestine
COSM3237296c.1475C>Gp.S492CSubstitution - MissenseLiver
COSM5548503c.3686C>Ap.A1229ESubstitution - MissenseProstate
COSM1319283c.2479delCp.Q827fs*8Deletion - FrameshiftHaematopoietic_and_lymphoid_tissue
COSM3237309c.2070A>Gp.K690KSubstitution - coding silentLarge_intestine
COSM3237368c.5160C>Tp.F1720FSubstitution - coding silentSkin
COSM1433372c.1489G>Ap.A497TSubstitution - MissenseLarge_intestine
COSM3850442c.5240C>Tp.A1747VSubstitution - MissenseStomach
COSM1696223c.2927C>Tp.S976FSubstitution - MissenseSkin
COSM589490c.3013G>Cp.E1005QSubstitution - MissenseStomach
COSM5709466c.3151G>Ap.G1051RSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM3608976c.1906C>Tp.P636SSubstitution - MissenseSkin
COSM1211728c.3939A>Gp.I1313MSubstitution - MissenseLarge_intestine
COSM1061345c.3003C>Tp.L1001LSubstitution - coding silentEndometrium
COSM71279c.2543A>Gp.N848SSubstitution - MissenseCentral_nervous_system
COSM4896899c.3966C>Tp.S1322SSubstitution - coding silentSkin
COSM3237340c.3947C>Tp.P1316LSubstitution - MissenseSkin
COSM4141429c.2699A>Gp.Q900RSubstitution - MissenseOvary
COSM1671899c.2817C>Ap.F939LSubstitution - MissenseLarge_intestine
COSM1061347c.3073C>Tp.R1025CSubstitution - MissenseEndometrium
COSM4804842c.3864C>Tp.T1288TSubstitution - coding silentLiver
COSM735550c.1449G>Cp.L483FSubstitution - MissenseLung
COSM1671898c.2743C>Tp.R915CSubstitution - MissenseLiver
COSM4642944c.5242G>Ap.V1748ISubstitution - MissenseLarge_intestine
COSM448654c.3489T>Cp.G1163GSubstitution - coding silentThyroid
COSM735551c.963A>Gp.R321RSubstitution - coding silentLung
COSM1061359c.4253C>Tp.S1418LSubstitution - MissenseEndometrium
COSM1619531c.3090_3091insTAp.C1031fs*51Insertion - FrameshiftLiver
COSM3608981c.2883C>Tp.P961PSubstitution - coding silentSkin
COSM3608982c.3472G>Ap.E1158KSubstitution - MissenseSkin
COSM5004281c.852C>Gp.G284GSubstitution - coding silentHaematopoietic_and_lymphoid_tissue
COSM1433385c.4626C>Tp.N1542NSubstitution - coding silentLarge_intestine
COSM5356601c.1124G>Ap.G375DSubstitution - MissenseLarge_intestine
COSM217332c.5025G>Tp.Q1675HSubstitution - MissenseLiver
COSM3237372c.5276C>Tp.A1759VSubstitution - MissenseLarge_intestine
COSM3993991c.4988A>Gp.Y1663CSubstitution - MissenseKidney
COSM5975362c.1373C>Tp.S458LSubstitution - MissenseUpper_aerodigestive_tract
COSM4694947c.5008G>Ap.G1670SSubstitution - MissenseLarge_intestine
COSM217332c.5025G>Tp.Q1675HSubstitution - MissenseLiver
COSM4823094c.4707G>Ap.V1569VSubstitution - coding silentCervix
COSM215959c.5096A>Cp.K1699TSubstitution - MissenseCentral_nervous_system
COSM3608972c.1426C>Tp.L476FSubstitution - MissenseSkin
COSM402663c.350_351GG>ATp.W117YSubstitution - MissenseLung
COSM3661431c.2715C>Tp.I905ISubstitution - coding silentLiver
COSM1061313c.1374G>Tp.S458SSubstitution - coding silentEndometrium
COSM4817970c.4412-1G>Cp.?UnknownCervix
COSM3946874c.703G>Ap.E235KSubstitution - MissenseLung
COSM4694942c.2369C>Tp.P790LSubstitution - MissenseLarge_intestine
COSM3661431c.2715C>Tp.I905ISubstitution - coding silentLiver
COSM5402193c.2920C>Tp.P974SSubstitution - MissenseSkin
COSM149918c.714G>Ap.E238ESubstitution - coding silentStomach
COSM1696224c.4888C>Tp.R1630*Substitution - NonsenseSkin
COSM3918705c.1897C>Tp.P633SSubstitution - MissenseSkin
COSM1619532c.4934A>Tp.D1645VSubstitution - MissenseLiver
COSM5810418c.2895C>Tp.D965DSubstitution - coding silentLiver
COSM3393158c.2776A>Gp.K926ESubstitution - MissensePancreas
COSM282116c.3929A>Gp.D1310GSubstitution - MissenseLarge_intestine
COSM1433376c.2351C>Ap.S784*Substitution - NonsenseLarge_intestine
COSM4953478c.5163G>Tp.R1721SSubstitution - MissenseLiver
COSM5422404c.4794G>Tp.V1598VSubstitution - coding silentProstate
COSM4694945c.4162G>Tp.G1388WSubstitution - MissenseLarge_intestine
COSM1061355c.3881G>Ap.R1294QSubstitution - MissenseEndometrium
COSM3237277c.895T>Ap.S299TSubstitution - MissenseUpper_aerodigestive_tract
COSM312111c.1361G>Cp.R454PSubstitution - MissenseLung
COSM1061373c.4864G>Ap.A1622TSubstitution - MissenseEndometrium
COSM1061361c.4378C>Tp.R1460WSubstitution - MissenseSkin
COSM5039740c.4720G>Ap.G1574RSubstitution - MissenseLiver
COSM4965357c.4529C>Gp.P1510RSubstitution - MissensePancreas
COSM1486324c.4976G>Ap.R1659HSubstitution - MissenseBreast
COSM1061369c.4739G>Tp.G1580VSubstitution - MissenseEndometrium
COSM1633957c.2299delAp.N767fs*28Deletion - FrameshiftLiver
COSM1696222c.671C>Tp.S224FSubstitution - MissenseSkin
COSM5402194c.3888C>Tp.L1296LSubstitution - coding silentSkin
COSM1061307c.436C>Tp.R146WSubstitution - MissenseEndometrium
COSM216690c.2890A>Gp.S964GSubstitution - MissensePancreas
COSM3237263c.351G>Ap.W117*Substitution - NonsenseLarge_intestine
COSM3237311c.2180C>Tp.S727LSubstitution - MissenseLarge_intestine
COSM3993989c.681T>Cp.R227RSubstitution - coding silentKidney
COSM1211726c.2860C>Tp.R954CSubstitution - MissenseSkin
COSM30318c.2255T>Gp.V752GSubstitution - MissenseKidney
COSM3608971c.1087A>Cp.N363HSubstitution - MissenseSkin
COSM4440022c.3946delCp.P1317fs*10Deletion - FrameshiftLarge_intestine
COSM1319282c.2813G>Ap.R938HSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM4943079c.3494G>Cp.G1165ASubstitution - MissenseLiver
COSM4155468c.4594G>Tp.V1532LSubstitution - MissenseKidney
COSM5060648c.2827C>Tp.R943WSubstitution - MissenseStomach
COSM4382809c.3988G>Ap.A1330TSubstitution - MissenseLarge_intestine
COSM110507c.723G>Ap.S241SSubstitution - coding silentSkin
COSM4900016c.301C>Tp.R101CSubstitution - MissenseSkin
COSM3661429c.976G>Ap.G326RSubstitution - MissenseLiver
COSM5591486c.3754C>Tp.H1252YSubstitution - MissenseSkin
COSM3608975c.1874C>Tp.P625LSubstitution - MissenseSkin
COSM4804842c.3864C>Tp.T1288TSubstitution - coding silentLiver
COSM3608977c.1907C>Tp.P636LSubstitution - MissenseSkin
COSM5549815c.122C>Tp.A41VSubstitution - MissenseProstate
COSM1433381c.3193C>Tp.R1065CSubstitution - MissenseLarge_intestine
COSM4607886c.4463G>Tp.W1488LSubstitution - MissenseAdrenal_gland
COSM1255491c.4435C>Tp.Q1479*Substitution - NonsenseOesophagus
COSM448653c.952G>Ap.E318KSubstitution - MissenseBreast
COSM1061347c.3073C>Tp.R1025CSubstitution - MissenseEndometrium
COSM5402196c.4896T>Cp.V1632VSubstitution - coding silentSkin
COSM5665256c.5217C>Tp.I1739ISubstitution - coding silentSoft_tissue
COSM3237307c.1878C>Ap.P626PSubstitution - coding silentLarge_intestine
COSM3357854c.3146G>Ap.G1049ESubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM3608986c.3941C>Tp.P1314LSubstitution - MissenseSkin
COSM1719243c.1079C>Tp.T360ISubstitution - MissenseSkin
COSM1211727c.4946A>Gp.D1649GSubstitution - MissenseLarge_intestine
COSM3608979c.2094C>Tp.S698SSubstitution - coding silentSkin
COSM5402191c.2538C>Tp.G846GSubstitution - coding silentSkin
COSM3237317c.2405G>Ap.R802QSubstitution - MissenseLarge_intestine
COSM4971212c.2452_2460delCTGTCAGATp.L821_D823delLSDDeletion - In frameCentral_nervous_system
COSM420408c.3749A>Gp.E1250GSubstitution - MissenseUrinary_tract
COSM3237274c.849T>Cp.D283DSubstitution - coding silentLarge_intestine
COSM4694944c.3525G>Ap.P1175PSubstitution - coding silentLarge_intestine
COSM3661430c.2628A>Tp.K876NSubstitution - MissenseLiver
COSM3850430c.555A>Gp.Q185QSubstitution - coding silentStomach
COSM4964491c.2322C>Tp.G774GSubstitution - coding silentPancreas
COSM25322c.3933A>Gp.T1311TSubstitution - coding silentUpper_aerodigestive_tract
COSM3850435c.1263A>Gp.A421ASubstitution - coding silentStomach
COSM1433382c.3911T>Ap.L1304HSubstitution - MissenseLarge_intestine
COSM77942c.4249G>Cp.V1417LSubstitution - MissenseOvary
COSM5459151c.2832-6T>Gp.?UnknownLarge_intestine
COSM3734243c.4216C>Tp.R1406WSubstitution - MissensePancreas
COSM1433375c.2345_2346insGp.D782fs*11Insertion - FrameshiftLarge_intestine
COSM3850433c.777C>Tp.S259SSubstitution - coding silentStomach
COSM3237281c.1041C>Tp.V347VSubstitution - coding silentUpper_aerodigestive_tract
COSM5402195c.4887C>Tp.L1629LSubstitution - coding silentSkin
COSM3237367c.5136C>Tp.H1712HSubstitution - coding silentLarge_intestine
COSM5060645c.1440G>Ap.S480SSubstitution - coding silentStomach
COSM1433368c.961C>Tp.R321*Substitution - NonsenseLarge_intestine
COSM5486448c.2811C>Tp.C937CSubstitution - coding silentLarge_intestine
COSM4460051c.1151C>Tp.P384LSubstitution - MissenseSkin
COSM4694943c.2551C>Tp.R851CSubstitution - MissenseLarge_intestine
COSM3850437c.1769A>Cp.D590ASubstitution - MissenseStomach
COSM3608973c.1593C>Tp.S531SSubstitution - coding silentSkin
COSM3850431c.583C>Tp.P195SSubstitution - MissenseStomach
COSM5720373c.3621C>Tp.A1207ASubstitution - coding silentSkin
COSM1753996c.795A>Tp.K265NSubstitution - MissenseUrinary_tract
COSM1061353c.3848C>Tp.A1283VSubstitution - MissenseEndometrium
COSM1061329c.1804delAp.T602fs*9Deletion - FrameshiftEndometrium
COSM97867c.5051C>Tp.P1684LSubstitution - MissenseUpper_aerodigestive_tract
COSM3850432c.679C>Tp.R227CSubstitution - MissenseStomach
COSM5000605c.353C>Ap.P118QSubstitution - MissensePancreas
COSM5603867c.339C>Tp.S113SSubstitution - coding silentSkin
COSM4644634c.946G>Tp.G316*Substitution - NonsenseLarge_intestine
COSM1061317c.1399C>Ap.L467MSubstitution - MissenseEndometrium
COSM1061327c.1698A>Gp.S566SSubstitution - coding silentEndometrium
COSM1753998c.1809A>Tp.P603PSubstitution - coding silentUrinary_tract
COSM3927460c.534T>Cp.V178VSubstitution - coding silentHaematopoietic_and_lymphoid_tissue
COSM1696224c.4888C>Tp.R1630*Substitution - NonsenseSkin
COSM4989484c.3622A>Gp.I1208VSubstitution - MissenseSoft_tissue
COSM1061315c.1376G>Ap.G459ESubstitution - MissenseEndometrium
COSM219514c.3340G>Ap.A1114TSubstitution - MissenseBreast
COSM4965338c.4507G>Ap.E1503KSubstitution - MissensePancreas
COSM3608983c.3517C>Tp.P1173SSubstitution - MissenseSkin
COSM4534696c.2110G>Ap.G704SSubstitution - MissenseSkin
COSM1061343c.2340G>Ap.P780PSubstitution - coding silentEndometrium
COSM1619530c.1553A>Gp.D518GSubstitution - MissenseLiver
COSM3608974c.1702C>Tp.L568LSubstitution - coding silentSkin
COSM4818718c.2329C>Gp.L777VSubstitution - MissenseCervix
COSM1061363c.4433G>Tp.G1478VSubstitution - MissenseEndometrium
COSM4440022c.3946delCp.P1317fs*10Deletion - FrameshiftLarge_intestine
COSM1433373c.1554C>Ap.D518ESubstitution - MissenseLarge_intestine
COSM3826846c.3981G>Cp.K1327NSubstitution - MissenseBreast
COSM116037c.248A>Gp.H83RSubstitution - MissenseOvary
COSM1061333c.1961C>Tp.S654FSubstitution - MissenseEndometrium
COSM1696224c.4888C>Tp.R1630*Substitution - NonsenseSkin
COSM5418685c.2879G>Ap.S960NSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM1753996c.795A>Tp.K265NSubstitution - MissenseUrinary_tract
COSM1211729c.3820T>Gp.F1274VSubstitution - MissenseLarge_intestine
COSM1061371c.4828C>Ap.P1610TSubstitution - MissenseEndometrium
COSM3608984c.3631C>Tp.P1211SSubstitution - MissenseSkin
COSM3728127c.4130A>Cp.D1377ASubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM3850440c.4428A>Cp.E1476DSubstitution - MissenseStomach
COSM735547c.4583C>Gp.P1528RSubstitution - MissenseLung
COSM5952540c.4260A>Gp.V1420VSubstitution - coding silentOesophagus
COSM5484738c.2807C>Tp.A936VSubstitution - MissenseLarge_intestine
COSM1696224c.4888C>Tp.R1630*Substitution - NonsenseSkin
COSM4964524c.3124C>Gp.H1042DSubstitution - MissensePancreas
COSM3237276c.894A>Tp.A298ASubstitution - coding silentUpper_aerodigestive_tract
COSM1619530c.1553A>Gp.D518GSubstitution - MissenseLiver
COSM5459150c.2768G>Ap.R923QSubstitution - MissenseLarge_intestine
COSM5011495c.655G>Cp.V219LSubstitution - MissenseKidney
COSM5797081c.3464C>Gp.S1155CSubstitution - MissenseBreast
COSM462074c.3691C>Tp.Q1231*Substitution - NonsenseCervix
COSM3975186c.269T>Ap.L90HSubstitution - MissenseCentral_nervous_system
COSM4450083c.4398delCp.F1466fs*32Deletion - FrameshiftSkin
COSM3237276c.894A>Tp.A298ASubstitution - coding silentUpper_aerodigestive_tract
COSM3237310c.2171G>Ap.R724HSubstitution - MissenseStomach
COSM4392913c.1006G>Tp.D336YSubstitution - MissenseProstate
COSM149918c.714G>Ap.E238ESubstitution - coding silentLarge_intestine
COSM4694939c.1661G>Ap.R554QSubstitution - MissenseLarge_intestine
COSM397282c.712G>Ap.E238KSubstitution - MissenseLung
COSM402665c.4619T>Cp.M1540TSubstitution - MissenseLung
COSM4904579c.3725C>Tp.S1242FSubstitution - MissenseSkin
COSM4894748c.4636T>Cp.L1546LSubstitution - coding silentSkin
COSM448655c.5257G>Ap.A1753TSubstitution - MissenseBreast
COSM30414c.1378G>Ap.E460KSubstitution - MissenseLung
COSM5585564c.4330G>Ap.D1444NSubstitution - MissenseSkin
COSM1061359c.4253C>Tp.S1418LSubstitution - MissenseEndometrium
COSM4694946c.4504T>Cp.F1502LSubstitution - MissenseLarge_intestine
COSM4441508c.2767C>Tp.R923WSubstitution - MissenseLarge_intestine
COSM5037511c.2698C>Tp.Q900*Substitution - NonsenseSkin
COSM3608990c.5039C>Tp.A1680VSubstitution - MissenseSkin
COSM5912252c.1388G>Ap.R463KSubstitution - MissenseSkin
COSM30414c.1378G>Ap.E460KSubstitution - MissenseLung
COSM5925175c.3526G>Ap.D1176NSubstitution - MissenseSkin
COSM71279c.2543A>Gp.N848SSubstitution - MissenseOvary
COSM3850436c.1757G>Tp.G586VSubstitution - MissenseStomach
COSM3993990c.758A>Cp.D253ASubstitution - MissenseKidney
COSM3702708c.2832-5C>Gp.?UnknownLiver
COSM3850429c.460T>Cp.L154LSubstitution - coding silentStomach
COSM1696224c.4888C>Tp.R1630*Substitution - NonsenseSkin
COSM4804748c.13G>Ap.A5TSubstitution - MissenseLiver
COSM5501513c.715A>Gp.I239VSubstitution - MissenseBiliary_tract
COSM3237296c.1475C>Gp.S492CSubstitution - MissenseLiver
COSM5918682c.479G>Ap.G160ESubstitution - MissenseSkin
COSM4961363c.2630-1G>Ap.?UnknownLiver
COSM1061361c.4378C>Tp.R1460WSubstitution - MissenseLarge_intestine
COSM1061335c.2054C>Ap.S685YSubstitution - MissenseEndometrium
COSM1328261c.5274G>Ap.L1758LSubstitution - coding silentOvary
COSM3661432c.3113T>Gp.L1038RSubstitution - MissenseLiver
COSM4694940c.1873delCp.K627fs*60Deletion - FrameshiftLarge_intestine
COSM6011943c.2344G>Ap.D782NSubstitution - MissenseSkin
COSM4989484c.3622A>Gp.I1208VSubstitution - MissenseSoft_tissue
COSM4435528c.538G>Tp.A180SSubstitution - MissenseOesophagus
COSM4425061c.1273A>Cp.T425PSubstitution - MissenseOesophagus
COSM1061361c.4378C>Tp.R1460WSubstitution - MissenseEndometrium
COSM735548c.4347G>Cp.R1449SSubstitution - MissenseLung
COSM3918708c.3015G>Ap.E1005ESubstitution - coding silentSkin
COSM1255490c.3363A>Cp.K1121NSubstitution - MissenseOesophagus
COSM4440022c.3946delCp.P1317fs*10Deletion - FrameshiftLarge_intestine
COSM4492249c.3942C>Tp.P1314PSubstitution - coding silentSkin
COSM5402188c.238G>Ap.V80ISubstitution - MissenseSkin
COSM4818723c.2286C>Gp.L762LSubstitution - coding silentCervix
COSM3237273c.845A>Gp.K282RSubstitution - MissenseUpper_aerodigestive_tract
COSM3608980c.2133C>Tp.T711TSubstitution - coding silentSkin
COSM1061341c.2302G>Ap.V768ISubstitution - MissenseEndometrium
COSM3918709c.3724T>Gp.S1242ASubstitution - MissenseSkin
COSM3737792c.3972+9C>Gp.?UnknownSoft_tissue
COSM282114c.1445C>Ap.P482HSubstitution - MissenseLarge_intestine
COSM4481478c.2512C>Tp.P838SSubstitution - MissenseSkin
COSM5720373c.3621C>Tp.A1207ASubstitution - coding silentSkin
COSM1061343c.2340G>Ap.P780PSubstitution - coding silentLarge_intestine
COSM1061349c.3149T>Cp.F1050SSubstitution - MissenseEndometrium
COSM3237280c.1008T>Gp.D336ESubstitution - MissenseUpper_aerodigestive_tract
COSM420406c.4693G>Cp.D1565HSubstitution - MissenseUrinary_tract
COSM589489c.3076G>Tp.G1026CSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM1753998c.1809A>Tp.P603PSubstitution - coding silentUrinary_tract
COSM3237279c.981G>Tp.G327GSubstitution - coding silentUpper_aerodigestive_tract
COSM4780544c.4736A>Gp.E1579GSubstitution - MissenseLiver
COSM5772390c.3308-7T>Ap.?UnknownBreast
COSM1310574c.4382A>Gp.D1461GSubstitution - MissenseUrinary_tract
COSM1696224c.4888C>Tp.R1630*Substitution - NonsenseSkin
COSM1433365c.853C>Tp.R285WSubstitution - MissenseLarge_intestine
COSM3918706c.2076C>Tp.L692LSubstitution - coding silentSkin
COSM5060646c.1582C>Tp.Q528*Substitution - NonsenseStomach
COSM26609c.247C>Tp.H83YSubstitution - MissenseKidney
COSM5720373c.3621C>Tp.A1207ASubstitution - coding silentSkin
COSM1061331c.1918T>Cp.F640LSubstitution - MissenseEndometrium
COSM1061351c.3238T>Cp.L1080LSubstitution - coding silentEndometrium
COSM1486324c.4976G>Ap.R1659HSubstitution - MissenseLarge_intestine
COSM30413c.1177C>Tp.P393SSubstitution - MissenseLung
COSM1310573c.2181G>Ap.S727SSubstitution - coding silentUrinary_tract
COSM3918707c.2148C>Tp.S716SSubstitution - coding silentSkin
COSM1061361c.4378C>Tp.R1460WSubstitution - MissenseEndometrium
COSM1211730c.3082C>Tp.R1028WSubstitution - MissenseLarge_intestine
COSM5356601c.1124G>Ap.G375DSubstitution - MissenseLarge_intestine
COSM5591487c.717C>Tp.I239ISubstitution - coding silentSkin
COSM4935188c.2966A>Gp.Y989CSubstitution - MissenseLiver
COSM1433364c.532G>Tp.V178FSubstitution - MissenseLarge_intestine
COSM4432372c.3652C>Gp.P1218ASubstitution - MissenseOesophagus
COSM1671901c.4330G>Tp.D1444YSubstitution - MissenseLarge_intestine
COSM3237277c.895T>Ap.S299TSubstitution - MissenseUpper_aerodigestive_tract
COSM3237309c.2070A>Gp.K690KSubstitution - coding silentLarge_intestine
COSM1433380c.3046+1G>Ap.?UnknownLarge_intestine
COSM1642609c.3119A>Gp.N1040SSubstitution - MissenseStomach
COSM4472153c.1763C>Tp.S588FSubstitution - MissenseSkin
> Text Mining based Variations
 
PMID Variation Cancer Evidence
21536236mutationMyelodysplastic SyndromeThis case, together with previously published studies, suggests that the proximal boundary of the common deleted region may lie within the KDM3B gene.
Summary
SymbolKDM3B
Namelysine demethylase 3B
Aliases KIAA1082; NET22; C5orf7; JMJD1B; chromosome 5 open reading frame 7; jumonji domain containing 1B; 5qNCA; jmj ......
Location5q31.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Post-translational modification (PTM)
> Post-translational modification (PTM)
 
 Filter By:
Uniprot ID Position Amino Acid Description Upstream Enzyme Affected By Mutation Amino Acid Sequence Variant
Q7LBC6361KN6-acetyllysine-NoNone detected
Q7LBC6492SPhosphoserine-NoNone detected
Q7LBC6546SPhosphoserine-NoNone detected
Q7LBC6556SPhosphoserine-NoNone detected
Q7LBC6560SPhosphoserine-NoNone detected
Q7LBC6614TPhosphothreonine-NoNone detected
Q7LBC6766SPhosphoserine-NoNone detected
Q7LBC6773SPhosphoserine-NoNone detected
Q7LBC6778SPhosphoserine-NoNone detected
Q7LBC6779SPhosphoserine-NoNone detected
Q7LBC6798SPhosphoserine-NoNone detected
Q7LBC61253SPhosphoserine-NoNone detected
Q7LBC61259SPhosphoserine-NoNone detected
Summary
SymbolKDM3B
Namelysine demethylase 3B
Aliases KIAA1082; NET22; C5orf7; JMJD1B; chromosome 5 open reading frame 7; jumonji domain containing 1B; 5qNCA; jmj ......
Location5q31.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Expression analysis in primary tumor tissue from TCGA
> Expression level in cancer cell line from CCLE
> Expression level in human normal tissue from HPA
> Text mining based expression change
> The Cancer Genome Atlas (TCGA)
 


  Differential expression analysis for cancers with more than 10 normal samples
Cancer Full Name # N # T Median (N) Median (T) LogFC Adj. P Status
BLCABladder urothelial carcinoma194086.8866.353-0.4070.00733NS
BRCABreast invasive carcinoma11211007.2097.003-0.2366.46e-06NS
CESCCervical and endocervical cancers33066.4716.493NANANA
COADColon adenocarcinoma414596.9096.779-0.0880.265NS
ESCAEsophageal carcinoma111857.1426.87-0.260.0892NS
GBMGlioblastoma multiforme51666.566.631NANANA
HNSCHead and Neck squamous cell carcinoma445226.516.23-0.3210.00188NS
KIRCKidney renal clear cell carcinoma725347.0626.908-0.1790.00168NS
KIRPKidney renal papillary cell carcinoma322916.896.722-0.1490.128NS
LAMLAcute Myeloid Leukemia0173NA7.856NANANA
LGGBrain Lower Grade Glioma0530NA7.358NANANA
LIHCLiver hepatocellular carcinoma503734.9415.3260.3465.95e-05NS
LUADLung adenocarcinoma595176.776.693-0.0140.854NS
LUSCLung squamous cell carcinoma515016.7656.343-0.3282.18e-06NS
OVOvarian serous cystadenocarcinoma0307NA6.785NANANA
PAADPancreatic adenocarcinoma41796.6446.658NANANA
PCPGPheochromocytoma and Paraganglioma31846.5166.339NANANA
PRADProstate adenocarcinoma524987.0366.811-0.2020.00384NS
READRectum adenocarcinoma101676.756.722-0.0160.944NS
SARCSarcoma22636.2696.257NANANA
SKCMSkin Cutaneous Melanoma14726.5866.589NANANA
STADStomach adenocarcinoma354156.816.90.1020.252NS
TGCTTesticular Germ Cell Tumors0156NA7.236NANANA
THCAThyroid carcinoma595096.9966.952-0.0110.866NS
THYMThymoma21207.2897.207NANANA
UCECUterine Corpus Endometrial Carcinoma355466.8786.554-0.3490.000685NS
> Cancer Cell Line Encyclopedia (CCLE)
 



Tissue Cell Line Expression Level (Microarray)
Autonomic ganglia CHP126 10.1
Autonomic ganglia CHP212 8.7
Autonomic ganglia IMR32 9.8
Autonomic ganglia KELLY 8.8
Autonomic ganglia KPNRTBM1 9.8
Autonomic ganglia KPNSI9S 8.5
Autonomic ganglia KPNYN 9.5
Autonomic ganglia MHHNB11 9.8
Autonomic ganglia NB1 9.4
Autonomic ganglia NH6 9.2
Autonomic ganglia SHSY5Y 10
Autonomic ganglia SIMA 10
Autonomic ganglia SKNAS 8.6
Autonomic ganglia SKNBE2 9.5
Autonomic ganglia SKNDZ 9.7
Autonomic ganglia SKNFI 8.6
Autonomic ganglia SKNSH 8.7
Biliary tract HUCCT1 8.9
Biliary tract HUH28 8.2
Biliary tract SNU1079 9.7
Biliary tract SNU1196 9.5
Biliary tract SNU245 9.6
Biliary tract SNU308 9.5
Biliary tract SNU478 9.4
Bone 143B 8.5
Bone A673 8.8
Bone CADOES1 9.6
Bone CAL78 8.8
Bone G292CLONEA141B1 8.2
Bone HOS 8.5
Bone HS706T 8.3
Bone HS737T 8
Bone HS819T 8
Bone HS821T 8.7
Bone HS822T 8
Bone HS863T 8.6
Bone HS870T 7.7
Bone HS888T 9
Bone MG63 9.1
Bone MHHES1 9.7
Bone OUMS27 8
Bone RDES 8.7
Bone SJSA1 8.5
Bone SKES1 8.9
Bone SKNMC 9.2
Bone SW1353 8.5
Bone T173 7.7
Bone TC71 8.4
Bone U2OS 8.3
Breast AU565 8.5
Breast BT20 8.8
Breast BT474 9
Breast BT483 10.1
Breast BT549 9.1
Breast CAL120 9.3
Breast CAL148 10.1
Breast CAL51 10.5
Breast CAL851 8.1
Breast CAMA1 9.6
Breast DU4475 9.1
Breast EFM192A 8.9
Breast EFM19 8.6
Breast EVSAT 8.4
Breast HCC1143 8.9
Breast HCC1187 9.2
Breast HCC1395 8.1
Breast HCC1419 9.3
Breast HCC1428 9.5
Breast HCC1500 9.2
Breast HCC1569 8.4
Breast HCC1599 9.2
Breast HCC1806 9.7
Breast HCC1937 8.9
Breast HCC1954 9.1
Breast HCC202 9
Breast HCC2157 9.1
Breast HCC2218 9.2
Breast HCC38 8.7
Breast HCC70 9
Breast HDQP1 9.5
Breast HMC18 9.1
Breast HS274T 8.8
Breast HS281T 8.5
Breast HS343T 8.6
Breast HS578T 7.5
Breast HS606T 7.7
Breast HS739T 8
Breast HS742T 7.7
Breast JIMT1 9
Breast KPL1 9.7
Breast MCF7 9
Breast MDAMB134VI 9.3
Breast MDAMB157 8.6
Breast MDAMB175VII 9.1
Breast MDAMB231 8
Breast MDAMB361 8.2
Breast MDAMB415 9.2
Breast MDAMB436 7.8
Breast MDAMB453 8.6
Breast MDAMB468 8.6
Breast SKBR3 8.5
Breast T47D 8.8
Breast UACC812 9.5
Breast UACC893 9.2
Breast YMB1 8.7
Breast ZR751 8.5
Breast ZR7530 9.8
Central nervous system 1321N1 7.7
Central nervous system 42MGBA 7.8
Central nervous system 8MGBA 7.3
Central nervous system A172 8.4
Central nervous system AM38 8.6
Central nervous system BECKER 8.7
Central nervous system CAS1 9
Central nervous system CCFSTTG1 8.5
Central nervous system D283MED 9.3
Central nervous system D341MED 9.2
Central nervous system DAOY 9.1
Central nervous system DBTRG05MG 7.8
Central nervous system DKMG 9
Central nervous system GAMG 8.2
Central nervous system GB1 9.4
Central nervous system GI1 7.9
Central nervous system GMS10 8.2
Central nervous system GOS3 8.2
Central nervous system H4 9
Central nervous system HS683 8.5
Central nervous system KALS1 9.1
Central nervous system KG1C 9.3
Central nervous system KNS42 8.2
Central nervous system KNS60 8.9
Central nervous system KNS81 8.5
Central nervous system KS1 8.8
Central nervous system LN18 8.3
Central nervous system LN229 8.8
Central nervous system M059K 7.8
Central nervous system MOGGCCM 8.5
Central nervous system MOGGUVW 7.9
Central nervous system NMCG1 8.6
Central nervous system ONS76 8.8
Central nervous system SF126 8.3
Central nervous system SF295 7.9
Central nervous system SNB19 8.5
Central nervous system SNU1105 8.7
Central nervous system SNU201 9.5
Central nervous system SNU466 8.8
Central nervous system SNU489 9.7
Central nervous system SNU626 9.5
Central nervous system SNU738 9
Central nervous system SW1088 9.2
Central nervous system SW1783 8.5
Central nervous system T98G 8.6
Central nervous system TM31 9
Central nervous system U118MG 8.7
Central nervous system U138MG 8.1
Central nervous system U251MG 8.7
Central nervous system U87MG 7.4
Central nervous system YH13 8.3
Central nervous system YKG1 8.5
Endometrium AN3CA 9.4
Endometrium COLO684 10.4
Endometrium EFE184 7.6
Endometrium EN 8.6
Endometrium ESS1 8.3
Endometrium HEC108 9.3
Endometrium HEC151 8.4
Endometrium HEC1A 9.3
Endometrium HEC1B 9.9
Endometrium HEC251 7.9
Endometrium HEC265 8.9
Endometrium HEC50B 8.8
Endometrium HEC59 8.6
Endometrium HEC6 9.2
Endometrium ISHIKAWAHERAKLIO02ER 9.5
Endometrium JHUEM1 9
Endometrium JHUEM2 9.1
Endometrium JHUEM3 9.6
Endometrium KLE 8.5
Endometrium MFE280 8.6
Endometrium MFE296 9.1
Endometrium MFE319 8.2
Endometrium RL952 8.9
Endometrium SNGM 9.2
Endometrium SNU1077 9.9
Endometrium SNU685 9.5
Endometrium TEN 9.4
Haematopoietic and lymphoid 697 10.4
Haematopoietic and lymphoid A3KAW 8.4
Haematopoietic and lymphoid A4FUK 9.2
Haematopoietic and lymphoid ALLSIL 9.9
Haematopoietic and lymphoid AML193 9.3
Haematopoietic and lymphoid AMO1 9.5
Haematopoietic and lymphoid BCP1 9.1
Haematopoietic and lymphoid BDCM 8.3
Haematopoietic and lymphoid BL41 9.8
Haematopoietic and lymphoid BL70 9.7
Haematopoietic and lymphoid BV173 10.3
Haematopoietic and lymphoid CA46 9.2
Haematopoietic and lymphoid CI1 9
Haematopoietic and lymphoid CMK115 7.8
Haematopoietic and lymphoid CMK86 9.5
Haematopoietic and lymphoid CMK 8
Haematopoietic and lymphoid CMLT1 10.1
Haematopoietic and lymphoid COLO775 9.4
Haematopoietic and lymphoid DAUDI 9
Haematopoietic and lymphoid DB 9.3
Haematopoietic and lymphoid DEL 9.8
Haematopoietic and lymphoid DND41 10.5
Haematopoietic and lymphoid DOHH2 10.1
Haematopoietic and lymphoid EB1 8.8
Haematopoietic and lymphoid EB2 8.9
Haematopoietic and lymphoid EHEB 9.4
Haematopoietic and lymphoid EJM 9.1
Haematopoietic and lymphoid EM2 10
Haematopoietic and lymphoid EOL1 10
Haematopoietic and lymphoid F36P 9.7
Haematopoietic and lymphoid GA10 9.2
Haematopoietic and lymphoid GDM1 9.4
Haematopoietic and lymphoid GRANTA519 9.7
Haematopoietic and lymphoid HDLM2 9.7
Haematopoietic and lymphoid HDMYZ 8.4
Haematopoietic and lymphoid HEL9217 9.1
Haematopoietic and lymphoid HEL 9.3
Haematopoietic and lymphoid HH 8.5
Haematopoietic and lymphoid HL60 8.7
Haematopoietic and lymphoid HPBALL 10.5
Haematopoietic and lymphoid HS604T 8.3
Haematopoietic and lymphoid HS611T 9.1
Haematopoietic and lymphoid HS616T 8.2
Haematopoietic and lymphoid HS751T 8.8
Haematopoietic and lymphoid HT 8.5
Haematopoietic and lymphoid HTK 9.2
Haematopoietic and lymphoid HUNS1 8.6
Haematopoietic and lymphoid HUT102 8.7
Haematopoietic and lymphoid HUT78 8.9
Haematopoietic and lymphoid JEKO1 10.4
Haematopoietic and lymphoid JK1 9.8
Haematopoietic and lymphoid JM1 9.3
Haematopoietic and lymphoid JURKAT 9.9
Haematopoietic and lymphoid JURLMK1 9.9
Haematopoietic and lymphoid JVM2 9.2
Haematopoietic and lymphoid JVM3 9.6
Haematopoietic and lymphoid K562 8.8
Haematopoietic and lymphoid KARPAS299 9.3
Haematopoietic and lymphoid KARPAS422 9.7
Haematopoietic and lymphoid KARPAS620 10.1
Haematopoietic and lymphoid KASUMI1 10
Haematopoietic and lymphoid KASUMI2 10.4
Haematopoietic and lymphoid KASUMI6 9.8
Haematopoietic and lymphoid KCL22 9.7
Haematopoietic and lymphoid KE37 10
Haematopoietic and lymphoid KE97 8.5
Haematopoietic and lymphoid KG1 8.6
Haematopoietic and lymphoid KHM1B 8.7
Haematopoietic and lymphoid KIJK 8.9
Haematopoietic and lymphoid KMH2 9.5
Haematopoietic and lymphoid KMM1 9.7
Haematopoietic and lymphoid KMS11 9.4
Haematopoietic and lymphoid KMS12BM 8.3
Haematopoietic and lymphoid KMS18 9.4
Haematopoietic and lymphoid KMS20 9
Haematopoietic and lymphoid KMS21BM 8.2
Haematopoietic and lymphoid KMS26 8.7
Haematopoietic and lymphoid KMS27 8.4
Haematopoietic and lymphoid KMS28BM 9.4
Haematopoietic and lymphoid KMS34 9
Haematopoietic and lymphoid KO52 9.6
Haematopoietic and lymphoid KOPN8 10.5
Haematopoietic and lymphoid KU812 9.7
Haematopoietic and lymphoid KYO1 10.4
Haematopoietic and lymphoid L1236 8.6
Haematopoietic and lymphoid L363 9.8
Haematopoietic and lymphoid L428 9.4
Haematopoietic and lymphoid L540 9.5
Haematopoietic and lymphoid LAMA84 10.6
Haematopoietic and lymphoid LOUCY 9.6
Haematopoietic and lymphoid LP1 9.6
Haematopoietic and lymphoid M07E 10.3
Haematopoietic and lymphoid MC116 8.9
Haematopoietic and lymphoid ME1 10.2
Haematopoietic and lymphoid MEC1 9.4
Haematopoietic and lymphoid MEC2 9.2
Haematopoietic and lymphoid MEG01 9.4
Haematopoietic and lymphoid MHHCALL2 10.3
Haematopoietic and lymphoid MHHCALL3 10.3
Haematopoietic and lymphoid MHHCALL4 10.3
Haematopoietic and lymphoid MINO 9.8
Haematopoietic and lymphoid MJ 8.7
Haematopoietic and lymphoid MM1S 8.2
Haematopoietic and lymphoid MOLM13 9.3
Haematopoietic and lymphoid MOLM16 9.4
Haematopoietic and lymphoid MOLM6 10.2
Haematopoietic and lymphoid MOLP2 8.4
Haematopoietic and lymphoid MOLP8 10
Haematopoietic and lymphoid MOLT13 10.3
Haematopoietic and lymphoid MOLT16 9.7
Haematopoietic and lymphoid MOLT4 8.9
Haematopoietic and lymphoid MONOMAC1 9.9
Haematopoietic and lymphoid MONOMAC6 9.5
Haematopoietic and lymphoid MOTN1 9.8
Haematopoietic and lymphoid MUTZ5 10.2
Haematopoietic and lymphoid MV411 9.6
Haematopoietic and lymphoid NALM19 10.7
Haematopoietic and lymphoid NALM1 10.4
Haematopoietic and lymphoid NALM6 10.5
Haematopoietic and lymphoid NAMALWA 10
Haematopoietic and lymphoid NB4 9.7
Haematopoietic and lymphoid NCIH929 8.7
Haematopoietic and lymphoid NCO2 9.7
Haematopoietic and lymphoid NOMO1 10
Haematopoietic and lymphoid NUDHL1 9.8
Haematopoietic and lymphoid NUDUL1 10.2
Haematopoietic and lymphoid OCIAML2 10
Haematopoietic and lymphoid OCIAML3 10.1
Haematopoietic and lymphoid OCIAML5 10.3
Haematopoietic and lymphoid OCILY10 9.2
Haematopoietic and lymphoid OCILY19 10.4
Haematopoietic and lymphoid OCILY3 8.5
Haematopoietic and lymphoid OCIM1 10
Haematopoietic and lymphoid OPM2 9
Haematopoietic and lymphoid P12ICHIKAWA 10.3
Haematopoietic and lymphoid P31FUJ 8.8
Haematopoietic and lymphoid P3HR1 8.9
Haematopoietic and lymphoid PCM6 9
Haematopoietic and lymphoid PEER 9.4
Haematopoietic and lymphoid PF382 10
Haematopoietic and lymphoid PFEIFFER 10.2
Haematopoietic and lymphoid PL21 9.8
Haematopoietic and lymphoid RAJI 8.9
Haematopoietic and lymphoid RCHACV 10.4
Haematopoietic and lymphoid REC1 9.6
Haematopoietic and lymphoid REH 9
Haematopoietic and lymphoid RI1 10.2
Haematopoietic and lymphoid RL 8.7
Haematopoietic and lymphoid RPMI8226 8.1
Haematopoietic and lymphoid RPMI8402 9.9
Haematopoietic and lymphoid RS411 9
Haematopoietic and lymphoid SEM 9.1
Haematopoietic and lymphoid SET2 9
Haematopoietic and lymphoid SIGM5 10.2
Haematopoietic and lymphoid SKM1 9.6
Haematopoietic and lymphoid SKMM2 9.2
Haematopoietic and lymphoid SR786 9.3
Haematopoietic and lymphoid ST486 9.2
Haematopoietic and lymphoid SUDHL10 9.8
Haematopoietic and lymphoid SUDHL1 9.6
Haematopoietic and lymphoid SUDHL4 10
Haematopoietic and lymphoid SUDHL5 9.8
Haematopoietic and lymphoid SUDHL6 9.7
Haematopoietic and lymphoid SUDHL8 9.4
Haematopoietic and lymphoid SUPB15 9.5
Haematopoietic and lymphoid SUPHD1 9.3
Haematopoietic and lymphoid SUPM2 9.5
Haematopoietic and lymphoid SUPT11 9.8
Haematopoietic and lymphoid SUPT1 9.1
Haematopoietic and lymphoid TALL1 9.9
Haematopoietic and lymphoid TF1 9.7
Haematopoietic and lymphoid THP1 9.5
Haematopoietic and lymphoid TO175T 8.2
Haematopoietic and lymphoid TOLEDO 9.2
Haematopoietic and lymphoid U266B1 8.5
Haematopoietic and lymphoid U937 9.2
Haematopoietic and lymphoid UT7 9.6
Haematopoietic and lymphoid WSUDLCL2 9.8
Kidney 769P 8.4
Kidney 786O 8.4
Kidney A498 8.4
Kidney A704 8.6
Kidney ACHN 8.3
Kidney BFTC909 9.3
Kidney CAKI1 8.8
Kidney CAKI2 7.6
Kidney CAL54 9.4
Kidney KMRC1 8.2
Kidney KMRC20 8.9
Kidney KMRC2 8.3
Kidney KMRC3 8.9
Kidney OSRC2 8.8
Kidney RCC10RGB 8.9
Kidney SNU1272 9.3
Kidney SNU349 9.3
Kidney TUHR10TKB 9.4
Kidney TUHR14TKB 9.1
Kidney TUHR4TKB 9
Kidney VMRCRCW 8.9
Kidney VMRCRCZ 8.7
Large intestine C2BBE1 9
Large intestine CCK81 9
Large intestine CL11 9.3
Large intestine CL14 9.6
Large intestine CL34 9.8
Large intestine CL40 9.8
Large intestine COLO205 9.1
Large intestine COLO320 9.7
Large intestine COLO678 9.6
Large intestine CW2 9.8
Large intestine DLD1 8.7
Large intestine GP2D 10.2
Large intestine HCC56 9.7
Large intestine HCT116 9.1
Large intestine HCT15 8.3
Large intestine HS675T 8.9
Large intestine HS698T 8.6
Large intestine HT115 9.8
Large intestine HT29 8.7
Large intestine HT55 9.6
Large intestine KM12 8.6
Large intestine LOVO 9.5
Large intestine LS1034 9.4
Large intestine LS123 9.8
Large intestine LS180 8.8
Large intestine LS411N 9.8
Large intestine LS513 10.6
Large intestine MDST8 9.1
Large intestine NCIH508 9.1
Large intestine NCIH716 8.4
Large intestine NCIH747 8.8
Large intestine OUMS23 9.5
Large intestine RCM1 9.2
Large intestine RKO 8.2
Large intestine SKCO1 10
Large intestine SNU1040 9.5
Large intestine SNU1197 9.1
Large intestine SNU175 8.9
Large intestine SNU283 9.7
Large intestine SNU407 9.6
Large intestine SNU503 9.3
Large intestine SNU61 9.7
Large intestine SNU81 10.1
Large intestine SNUC1 8.9
Large intestine SNUC2A 9
Large intestine SNUC4 9.9
Large intestine SNUC5 9.5
Large intestine SW1116 9.1
Large intestine SW1417 9
Large intestine SW1463 8.7
Large intestine SW403 9.1
Large intestine SW480 8.9
Large intestine SW48 8.2
Large intestine SW620 8.7
Large intestine SW837 10.5
Large intestine SW948 8.9
Large intestine T84 9.1
Liver ALEXANDERCELLS 9.1
Liver C3A 8.7
Liver HEP3B217 9.2
Liver HEPG2 7.9
Liver HLE 9.4
Liver HLF 8.3
Liver HUH1 8
Liver HUH6 9.6
Liver HUH7 8.7
Liver JHH1 8.6
Liver JHH2 8.1
Liver JHH4 7.9
Liver JHH5 8.7
Liver JHH6 9.7
Liver JHH7 9.1
Liver LI7 10
Liver PLCPRF5 8.5
Liver SKHEP1 9.4
Liver SNU182 8.6
Liver SNU387 8.5
Liver SNU398 8.8
Liver SNU423 8.5
Liver SNU449 8.8
Liver SNU475 8.9
Liver SNU761 9.2
Liver SNU878 8.5
Liver SNU886 9.6
Lung A549 8.3
Lung ABC1 8
Lung BEN 9.3
Lung CAL12T 8.4
Lung CALU1 8.2
Lung CALU3 9.4
Lung CALU6 8.6
Lung CHAGOK1 10.1
Lung COLO668 8.7
Lung COLO699 9.2
Lung CORL105 9.5
Lung CORL23 8.7
Lung CORL24 9.8
Lung CORL279 8.8
Lung CORL311 9.4
Lung CORL47 9.9
Lung CORL51 9
Lung CORL88 9.5
Lung CORL95 9.9
Lung CPCN 8.8
Lung DMS114 9.3
Lung DMS153 8.2
Lung DMS273 10
Lung DMS454 9.3
Lung DMS53 8.9
Lung DMS79 8.2
Lung DV90 8.6
Lung EBC1 8.9
Lung EPLC272H 8.3
Lung HARA 9
Lung HCC1171 9.3
Lung HCC1195 9.2
Lung HCC15 8
Lung HCC2279 9
Lung HCC2935 9.4
Lung HCC33 9.5
Lung HCC366 9.2
Lung HCC4006 9
Lung HCC44 7.7
Lung HCC78 9.6
Lung HCC827 9.6
Lung HCC95 9.9
Lung HLC1 9.5
Lung HLFA 7.8
Lung HS229T 8.1
Lung HS618T 8.3
Lung IALM 9.2
Lung KNS62 7.6
Lung LC1F 8.7
Lung LC1SQSF 8.7
Lung LCLC103H 9.7
Lung LCLC97TM1 9.8
Lung LK2 8.8
Lung LOUNH91 8.4
Lung LU65 8.9
Lung LU99 8.8
Lung LUDLU1 8.9
Lung LXF289 9.6
Lung MORCPR 8.3
Lung NCIH1048 9.5
Lung NCIH1092 9.4
Lung NCIH1105 9.7
Lung NCIH1155 8.8
Lung NCIH1184 9.3
Lung NCIH1299 8.8
Lung NCIH1339 9.8
Lung NCIH1341 8.6
Lung NCIH1355 7.9
Lung NCIH1373 8.9
Lung NCIH1385 9.2
Lung NCIH1395 7.9
Lung NCIH1435 8.7
Lung NCIH1436 9.7
Lung NCIH1437 8.7
Lung NCIH146 8.5
Lung NCIH1563 8.4
Lung NCIH1568 8.5
Lung NCIH1573 9
Lung NCIH1581 8.5
Lung NCIH1618 9.1
Lung NCIH1623 8.5
Lung NCIH1648 8.5
Lung NCIH1650 8.8
Lung NCIH1651 8.7
Lung NCIH1666 8.5
Lung NCIH1693 8.5
Lung NCIH1694 8.8
Lung NCIH1703 8.7
Lung NCIH1734 8.9
Lung NCIH1755 8.7
Lung NCIH1781 8.5
Lung NCIH1792 7.9
Lung NCIH1793 8.5
Lung NCIH1836 8.3
Lung NCIH1838 8.4
Lung NCIH1869 9.6
Lung NCIH1876 10.5
Lung NCIH1915 8.3
Lung NCIH1930 8.9
Lung NCIH1944 8.8
Lung NCIH1963 7.8
Lung NCIH196 7.9
Lung NCIH1975 8.4
Lung NCIH2009 9.1
Lung NCIH2023 8.4
Lung NCIH2029 9
Lung NCIH2030 7.5
Lung NCIH2066 8.8
Lung NCIH2081 9
Lung NCIH2085 8.8
Lung NCIH2087 8.8
Lung NCIH209 8.7
Lung NCIH2106 9.4
Lung NCIH2110 9.6
Lung NCIH211 8.9
Lung NCIH2122 8.3
Lung NCIH2126 9.2
Lung NCIH2141 9.3
Lung NCIH2170 8.7
Lung NCIH2171 7.8
Lung NCIH2172 9.5
Lung NCIH2196 8.6
Lung NCIH2227 8.9
Lung NCIH2228 8.6
Lung NCIH226 8.3
Lung NCIH2286 9.7
Lung NCIH2291 8.1
Lung NCIH2342 9.4
Lung NCIH2347 8.6
Lung NCIH23 8.7
Lung NCIH2405 9.5
Lung NCIH2444 8.2
Lung NCIH292 9.1
Lung NCIH322 8.3
Lung NCIH3255 9.4
Lung NCIH358 8.3
Lung NCIH441 8.7
Lung NCIH446 8.1
Lung NCIH460 8.2
Lung NCIH510 8
Lung NCIH520 9
Lung NCIH522 8.4
Lung NCIH524 8.7
Lung NCIH526 8.9
Lung NCIH596 9.3
Lung NCIH647 8.3
Lung NCIH650 10.3
Lung NCIH661 8.4
Lung NCIH69 9.6
Lung NCIH727 9.7
Lung NCIH810 8.4
Lung NCIH82 8.7
Lung NCIH838 8.5
Lung NCIH841 10.2
Lung NCIH854 8.9
Lung NCIH889 8.1
Lung PC14 8.2
Lung RERFLCAD1 8.9
Lung RERFLCAD2 8.7
Lung RERFLCAI 7.8
Lung RERFLCKJ 9
Lung RERFLCMS 8.5
Lung RERFLCSQ1 8.1
Lung SBC5 8.8
Lung SCLC21H 10
Lung SHP77 9.4
Lung SKLU1 7.8
Lung SKMES1 7.6
Lung SQ1 8.4
Lung SW1271 9
Lung SW1573 10.1
Lung SW900 7.4
Lung VMRCLCD 9.9
Lung VMRCLCP 9.6
Oesophagus COLO680N 9.4
Oesophagus ECGI10 9.3
Oesophagus KYSE140 9.4
Oesophagus KYSE150 8.5
Oesophagus KYSE180 7.9
Oesophagus KYSE270 8
Oesophagus KYSE30 10
Oesophagus KYSE410 8.6
Oesophagus KYSE450 8.5
Oesophagus KYSE510 9.1
Oesophagus KYSE520 8.5
Oesophagus KYSE70 8.8
Oesophagus OE19 8.7
Oesophagus OE33 8.8
Oesophagus TE10 9.4
Oesophagus TE11 8.6
Oesophagus TE14 10.2
Oesophagus TE15 8.6
Oesophagus TE1 7.7
Oesophagus TE4 9.1
Oesophagus TE5 9
Oesophagus TE6 9.6
Oesophagus TE8 9.4
Oesophagus TE9 8.8
Oesophagus TT 9.5
Ovary 59M 9.5
Ovary A2780 8.8
Ovary CAOV3 7.7
Ovary CAOV4 9.3
Ovary COLO704 9.2
Ovary COV318 8.5
Ovary COV362 9.9
Ovary COV434 9.5
Ovary COV504 9
Ovary COV644 9.7
Ovary EFO21 9
Ovary EFO27 8.7
Ovary ES2 8.1
Ovary FUOV1 8.5
Ovary HEYA8 7.6
Ovary HS571T 7.3
Ovary IGROV1 8.8
Ovary JHOC5 9.5
Ovary JHOM1 8.8
Ovary JHOM2B 9.9
Ovary JHOS2 9
Ovary JHOS4 8.3
Ovary KURAMOCHI 10.2
Ovary MCAS 8.3
Ovary NIHOVCAR3 8.9
Ovary OAW28 10
Ovary OAW42 10.2
Ovary OC314 9.1
Ovary OC316 8.9
Ovary ONCODG1 9.7
Ovary OV56 8
Ovary OV7 9.3
Ovary OV90 8.8
Ovary OVCAR4 8.8
Ovary OVCAR8 9.4
Ovary OVISE 8.5
Ovary OVK18 9.7
Ovary OVKATE 8.5
Ovary OVMANA 9.7
Ovary OVSAHO 8.4
Ovary OVTOKO 7.6
Ovary RMGI 8.4
Ovary RMUGS 8.9
Ovary SKOV3 8.9
Ovary SNU119 9.7
Ovary SNU840 9.4
Ovary SNU8 9.3
Ovary TOV112D 8.7
Ovary TOV21G 8.7
Ovary TYKNU 8.2
Pancreas ASPC1 9.3
Pancreas BXPC3 8.3
Pancreas CAPAN1 8.4
Pancreas CAPAN2 8.6
Pancreas CFPAC1 8.5
Pancreas DANG 8
Pancreas HPAC 10
Pancreas HPAFII 8.6
Pancreas HS766T 8
Pancreas HUPT3 8
Pancreas HUPT4 8.7
Pancreas KCIMOH1 8.8
Pancreas KLM1 10.5
Pancreas KP2 9.4
Pancreas KP3 8.2
Pancreas KP4 9.7
Pancreas L33 8.3
Pancreas MIAPACA2 9.4
Pancreas PANC0203 9.7
Pancreas PANC0213 8.4
Pancreas PANC0327 8.6
Pancreas PANC0403 7.6
Pancreas PANC0504 9.2
Pancreas PANC0813 8.4
Pancreas PANC1005 8.3
Pancreas PANC1 8.8
Pancreas PATU8902 8.3
Pancreas PATU8988S 9
Pancreas PATU8988T 8.7
Pancreas PK1 8.7
Pancreas PK45H 9.3
Pancreas PK59 8.5
Pancreas PL45 8.7
Pancreas PSN1 8.3
Pancreas QGP1 8.7
Pancreas SNU213 9.2
Pancreas SNU324 9.9
Pancreas SNU410 9.2
Pancreas SU8686 9
Pancreas SUIT2 9.6
Pancreas SW1990 7.7
Pancreas T3M4 9.2
Pancreas TCCPAN2 8.7
Pancreas YAPC 10.2
Pleura ACCMESO1 8.4
Pleura DM3 8.6
Pleura ISTMES1 9
Pleura ISTMES2 8.3
Pleura JL1 9.5
Pleura MPP89 7.7
Pleura MSTO211H 8.7
Pleura NCIH2052 8.3
Pleura NCIH2452 8.9
Pleura NCIH28 9.4
Prostate 22RV1 8.4
Prostate DU145 8.2
Prostate LNCAPCLONEFGC 8.7
Prostate MDAPCA2B 8.7
Prostate NCIH660 9.4
Prostate PC3 7.2
Prostate VCAP 9.5
Salivary gland A253 9.4
Salivary gland YD15 9
Skin A101D 7.8
Skin A2058 9.4
Skin A375 8.5
Skin C32 8.1
Skin CHL1 8.4
Skin CJM 9.6
Skin COLO679 8.1
Skin COLO741 7.9
Skin COLO783 9
Skin COLO792 9
Skin COLO800 7.7
Skin COLO818 8.8
Skin COLO829 7.9
Skin COLO849 8.6
Skin G361 7.9
Skin GRM 9.5
Skin HMCB 8.6
Skin HS294T 7.8
Skin HS600T 8
Skin HS688AT 8.2
Skin HS695T 8.6
Skin HS839T 8.1
Skin HS852T 9.2
Skin HS895T 7.5
Skin HS934T 8.7
Skin HS936T 8.6
Skin HS939T 8.4
Skin HS940T 8.2
Skin HS944T 8.1
Skin HT144 8.6
Skin IGR1 9.5
Skin IGR37 8.5
Skin IGR39 9.1
Skin IPC298 7.7
Skin K029AX 8.2
Skin LOXIMVI 8.4
Skin MALME3M 6.9
Skin MDAMB435S 8.7
Skin MELHO 8
Skin MELJUSO 8.1
Skin MEWO 9.6
Skin RPMI7951 8.8
Skin RVH421 8.4
Skin SH4 9.1
Skin SKMEL1 8.5
Skin SKMEL24 7.9
Skin SKMEL28 8.7
Skin SKMEL2 8.6
Skin SKMEL30 8.5
Skin SKMEL31 8.9
Skin SKMEL3 7.6
Skin SKMEL5 8.1
Skin UACC257 7.8
Skin UACC62 7.7
Skin WM115 8.3
Skin WM1799 9.5
Skin WM2664 8.3
Skin WM793 9.2
Skin WM88 9.3
Skin WM983B 9.4
Small intestine HUTU80 9.4
Soft tissue A204 7.9
Soft tissue G401 9
Soft tissue G402 8.6
Soft tissue GCT 8.2
Soft tissue HS729 8.3
Soft tissue HT1080 8.7
Soft tissue KYM1 9.3
Soft tissue MESSA 8.5
Soft tissue RD 9.4
Soft tissue RH30 10.1
Soft tissue RH41 10.1
Soft tissue RKN 8.6
Soft tissue S117 8.7
Soft tissue SJRH30 9.1
Soft tissue SKLMS1 8.4
Soft tissue SKUT1 9.2
Soft tissue TE125T 8.1
Soft tissue TE159T 8.2
Soft tissue TE441T 9.9
Soft tissue TE617T 9.1
Stomach 2313287 9
Stomach AGS 9
Stomach AZ521 9.7
Stomach ECC10 9.2
Stomach ECC12 10
Stomach FU97 8.4
Stomach GCIY 9.1
Stomach GSS 9.1
Stomach GSU 9.6
Stomach HGC27 8.8
Stomach HS746T 8.2
Stomach HUG1N 8.7
Stomach IM95 8.9
Stomach KATOIII 8.3
Stomach KE39 8.7
Stomach LMSU 8.7
Stomach MKN1 9.2
Stomach MKN45 10
Stomach MKN74 8.9
Stomach MKN7 9.2
Stomach NCCSTCK140 9
Stomach NCIN87 8.7
Stomach NUGC2 9
Stomach NUGC3 8.4
Stomach NUGC4 9.3
Stomach OCUM1 9.1
Stomach RERFGC1B 9.3
Stomach SH10TC 8.6
Stomach SNU16 8.1
Stomach SNU1 9.1
Stomach SNU216 9.5
Stomach SNU520 9
Stomach SNU5 9.1
Stomach SNU601 9.7
Stomach SNU620 9.6
Stomach SNU668 9.7
Stomach SNU719 8.9
Stomach TGBC11TKB 9.6
Thyroid 8305C 9.4
Thyroid 8505C 9.5
Thyroid BCPAP 8.9
Thyroid BHT101 9.4
Thyroid CAL62 9.5
Thyroid CGTHW1 8.8
Thyroid FTC133 9.1
Thyroid FTC238 9.7
Thyroid ML1 9.3
Thyroid SW579 7.2
Thyroid TT2609C02 9.2
Thyroid TT 9
Upper aerodigestive tract BHY 9.2
Upper aerodigestive tract BICR16 8.7
Upper aerodigestive tract BICR18 9.1
Upper aerodigestive tract BICR22 9.3
Upper aerodigestive tract BICR31 9.6
Upper aerodigestive tract BICR56 9.1
Upper aerodigestive tract BICR6 9.4
Upper aerodigestive tract CAL27 8.7
Upper aerodigestive tract CAL33 9.8
Upper aerodigestive tract DETROIT562 9.1
Upper aerodigestive tract FADU 9
Upper aerodigestive tract HS840T 8.1
Upper aerodigestive tract HSC2 8.8
Upper aerodigestive tract HSC3 8.7
Upper aerodigestive tract HSC4 9.2
Upper aerodigestive tract PECAPJ15 9.8
Upper aerodigestive tract PECAPJ34CLONEC12 9.6
Upper aerodigestive tract PECAPJ41CLONED2 9.2
Upper aerodigestive tract PECAPJ49 9.3
Upper aerodigestive tract SCC15 9.6
Upper aerodigestive tract SCC25 8.9
Upper aerodigestive tract SCC4 8.2
Upper aerodigestive tract SCC9 8.5
Upper aerodigestive tract SNU1076 8.9
Upper aerodigestive tract SNU1214 9
Upper aerodigestive tract SNU46 9.5
Upper aerodigestive tract SNU899 9.4
Upper aerodigestive tract YD10B 9.7
Upper aerodigestive tract YD38 9.6
Upper aerodigestive tract YD8 9.4
Urinary tract 5637 8.4
Urinary tract 639V 9.6
Urinary tract 647V 9.4
Urinary tract BC3C 9.2
Urinary tract BFTC905 9.2
Urinary tract CAL29 9.3
Urinary tract HS172T 8.5
Urinary tract HT1197 9.3
Urinary tract HT1376 8.4
Urinary tract J82 7.9
Urinary tract JMSU1 9.2
Urinary tract KMBC2 9
Urinary tract KU1919 9.1
Urinary tract RT11284 9.7
Urinary tract RT112 8.5
Urinary tract RT4 8.6
Urinary tract SCABER 7.7
Urinary tract SW1710 9.9
Urinary tract SW780 9.2
Urinary tract T24 8.2
Urinary tract TCCSUP 9.4
Urinary tract UMUC1 9.5
Urinary tract UMUC3 9.2
Urinary tract VMCUB1 9.2
> The Human Protein Atlas (HPA)
 


Tissue Expression Level (TPM)
Adipose tissue 19.4
Adrenal gland 18.4
Appendix 21.2
Bone marrow 14.5
Breast 29
Cerebral cortex 26.7
Cervix, uterine 31.7
Colon 21.1
Duodenum 17
Endometrium 31.6
Epididymis 32.6
Esophagus 14.9
Fallopian tube 36.7
Gallbladder 20.2
Heart muscle 12.7
Kidney 21.4
Liver 7.2
Lung 26.8
Lymph node 24.3
Ovary 34.7
Pancreas 3.1
Parathyroid gland 66.5
Placenta 27.4
Prostate 33.8
Rectum 25.3
Salivary gland 7.9
Seminal vesicle 33.7
Skeletal muscle 11.8
Skin 31.8
Small intestine 17.2
Smooth muscle 29.5
Spleen 32
Stomach 18.7
Testis 32.7
Thyroid gland 35.1
Tonsil 26.1
Urinary bladder 17.5
> Text Mining based Expression
 
PMID Expression Cancer Evidence
22120715OverexpressionProstate CarcinomaOur results show that the KDMs JARID1B, PHF8, KDM3A, KDM3B and KDM4A were highly expressed in clinical PrCa samples.
22345654UnderexpressionColorectal CarcinomaA low expression of the JMJD1B protein was positively correlated with the lymph node status (p=0.032), Dukes' classification (p=0.008) and TNM staging (p=0.022) of patients with CRC.
Summary
SymbolKDM3B
Namelysine demethylase 3B
Aliases KIAA1082; NET22; C5orf7; JMJD1B; chromosome 5 open reading frame 7; jumonji domain containing 1B; 5qNCA; jmj ......
Location5q31.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Somatic copy number alteration in primary tomur tissue
> The Cancer Genome Atlas (TCGA)
 


  Correlation between expression and SCNA as well as percentage of patients in different status.
Cancer Full Name # Sample R P % Loss % Neutral % Gain Status
BLCABladder urothelial carcinoma4040.3971.01e-1646.346.86.9Loss
BRCABreast invasive carcinoma10750.4363.14e-5121.657.920.6Neutral
CESCCervical and endocervical cancers2920.442.77e-1521.967.510.6Neutral
COADColon adenocarcinoma4490.3751.78e-1620.571.77.8Neutral
ESCAEsophageal carcinoma1830.4348.31e-1050.343.76Loss
GBMGlioblastoma multiforme1470.2810.00057712.280.37.5Neutral
HNSCHead and Neck squamous cell carcinoma5140.4022.38e-2138.354.96.8Loss
KIRCKidney renal clear cell carcinoma5250.4152.83e-230.838.760.6Gain
KIRPKidney renal papillary cell carcinoma2880.3661.51e-103.883.712.5Neutral
LAMLAcute Myeloid Leukemia1660.7582.71e-329910Neutral
LGGBrain Lower Grade Glioma5130.1766.18e-05989.31.8Neutral
LIHCLiver hepatocellular carcinoma3640.1860.0003591156.332.7Neutral
LUADLung adenocarcinoma5120.5172.54e-3637.744.717.6Loss
LUSCLung squamous cell carcinoma4980.3618.09e-1774.321.14.6Loss
OVOvarian serous cystadenocarcinoma3000.6071.48e-3142.342.315.3Loss
PAADPancreatic adenocarcinoma1770.4418.38e-1010.778.510.7Neutral
PCPGPheochromocytoma and Paraganglioma1620.3991.44e-077.4875.6Neutral
PRADProstate adenocarcinoma4910.2331.7e-076.189.84.1Neutral
READRectum adenocarcinoma1640.41.14e-0729.359.811Neutral
SARCSarcoma2550.4136.6e-1214.958.426.7Neutral
SKCMSkin Cutaneous Melanoma3670.528.4e-273355.611.4Neutral
STADStomach adenocarcinoma4130.4178.26e-1931.261.77Neutral
TGCTTesticular Germ Cell Tumors150-0.0150.85765.3322.7Loss
THCAThyroid carcinoma4970.1440.00127096.23.8Neutral
THYMThymoma1190.0810.3840.891.67.6Neutral
UCECUterine Corpus Endometrial Carcinoma5370.3278.3e-1515.679.35Neutral
Summary
SymbolKDM3B
Namelysine demethylase 3B
Aliases KIAA1082; NET22; C5orf7; JMJD1B; chromosome 5 open reading frame 7; jumonji domain containing 1B; 5qNCA; jmj ......
Location5q31.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Methylation level in the promoter region of CR
> Methylation level in the promoter region of CR
 


  Correlation between expression and methylation as well as differential methylation analysis.
Cancer Full Name R P # N # T Delta beta (T vs N) P value (T vs N) Status
BLCABladder urothelial carcinoma-0.1690.000476174080.0120.591NS/NA
BRCABreast invasive carcinoma-0.3158.68e-22837850.0021.92e-07NS/NA
CESCCervical and endocervical cancers-0.3112.88e-083306NANANS/NA
COADColon adenocarcinoma-0.2030.000284192970.0010.0925NS/NA
ESCAEsophageal carcinoma-0.1180.1029185NANANS/NA
GBMGlioblastoma multiforme-0.1950.12164NANANS/NA
HNSCHead and Neck squamous cell carcinoma-0.3910205220.0020.0053NS/NA
KIRCKidney renal clear cell carcinoma-0.090.0969243190.0510.000442NS/NA
KIRPKidney renal papillary cell carcinoma-0.2653.67e-06232750.0040.0772NS/NA
LAMLAcute Myeloid Leukemia-0.2060.007150170NANANS/NA
LGGBrain Lower Grade Glioma-0.2665.52e-100530NANANS/NA
LIHCLiver hepatocellular carcinoma-0.1710.00049841373-0.0020.000712NS/NA
LUADLung adenocarcinoma-0.0930.0417214560.0010.0283NS/NA
LUSCLung squamous cell carcinoma-0.2037.45e-058370NANANS/NA
OVOvarian serous cystadenocarcinoma-0.7170.036909NANANS/NA
PAADPancreatic adenocarcinoma-0.2590.0004184179NANANS/NA
PCPGPheochromocytoma and Paraganglioma-0.2130.003543184NANANS/NA
PRADProstate adenocarcinoma-0.285.88e-11354980.0041.35e-06NS/NA
READRectum adenocarcinoma-0.2880.00359299NANANS/NA
SARCSarcoma-0.2150.0004530263NANANS/NA
SKCMSkin Cutaneous Melanoma-0.2421.12e-071471NANANS/NA
STADStomach adenocarcinoma-0.2881.72e-080372NANANS/NA
TGCTTesticular Germ Cell Tumors-0.71700156NANANS/NA
THCAThyroid carcinoma-0.2551.07e-095050900.178NS/NA
THYMThymoma-0.1270.1642120NANANS/NA
UCECUterine Corpus Endometrial Carcinoma-0.1790.000111344310.0972.76e-09NS/NA
Summary
SymbolKDM3B
Namelysine demethylase 3B
Aliases KIAA1082; NET22; C5orf7; JMJD1B; chromosome 5 open reading frame 7; jumonji domain containing 1B; 5qNCA; jmj ......
Location5q31.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Primary tumor tissue from TCGA
> Normal tumor tissue from HPA
>The Cancer Genome Atlas (TCGA)
 
There is no record.
> The Human Protein Atlas (HPA)
 


Tissue Level Level Name
Adrenal gland 3 High
Appendix 3 High
Bone marrow 3 High
Breast 3 High
Bronchus 3 High
Caudate 3 High
Cerebellum 3 High
Cerebral cortex 3 High
Cervix, uterine 3 High
Colon 3 High
Duodenum 3 High
Endometrium 3 High
Epididymis 3 High
Esophagus 3 High
Fallopian tube 3 High
Gallbladder 3 High
Heart muscle 1 Low
Hippocampus 3 High
Kidney 3 High
Liver 2 Medium
Lung 3 High
Lymph node 3 High
Nasopharynx 3 High
Oral mucosa 3 High
Ovary 3 High
Pancreas 3 High
Parathyroid gland 3 High
Placenta 3 High
Prostate 3 High
Rectum 3 High
Salivary gland 3 High
Seminal vesicle 3 High
Skeletal muscle 3 High
Skin 3 High
Small intestine 3 High
Smooth muscle 2 Medium
Soft tissue 3 High
Spleen 3 High
Stomach 3 High
Testis 3 High
Thyroid gland 3 High
Tonsil 3 High
Urinary bladder 3 High
Vagina 2 Medium
Summary
SymbolKDM3B
Namelysine demethylase 3B
Aliases KIAA1082; NET22; C5orf7; JMJD1B; chromosome 5 open reading frame 7; jumonji domain containing 1B; 5qNCA; jmj ......
Location5q31.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Association between expresson and subtype
> Overall survival analysis based on expression
> Association between expresson and stage
> Association between expresson and grade
> Subtype
 


  Association between expresson and subtype.
Cancer Full Name # Patients P Value (Kruskal-Wallis) Association Source
BLCABladder urothelial carcinoma1280.849NS24476821
BRCABreast invasive carcinoma5211.4e-21Significant23000897
COADColon adenocarcinoma1490.305NS22810696
GBMGlioblastoma multiforme1570.00218Significant26824661
HNSCHead and Neck squamous cell carcinoma2791.37e-08Significant25631445
KIRPKidney renal papillary cell carcinoma1610.295NS26536169
LGGBrain Lower Grade Glioma5132.29e-19Significant26824661
LUADLung adenocarcinoma2300.00146Significant25079552
LUSCLung squamous cell carcinoma1784.97e-05Significant22960745
OVOvarian serous cystadenocarcinoma2870.0589NS21720365
PRADProstate adenocarcinoma3330.0281Significant26544944
READRectum adenocarcinoma670.293NS22810696
SKCMSkin Cutaneous Melanoma3150.0281Significant26091043
STADStomach adenocarcinoma2774.4e-05Significant25079317
THCAThyroid carcinoma3910.591NS25417114
UCECUterine Corpus Endometrial Carcinoma2320.515NS23636398
> Overall survival
 

  Overall survival analysis based on expression.
Cancer Full Name # Patients Hazard Ratio P Value (Log Rank Test) Association
BLCABladder urothelial carcinoma405 0.9260.723NS
BRCABreast invasive carcinoma1079 1.1910.435NS
CESCCervical and endocervical cancers291 1.4060.273NS
COADColon adenocarcinoma439 0.5530.053NS
ESCAEsophageal carcinoma184 0.7150.305NS
GBMGlioblastoma multiforme158 0.9170.743NS
HNSCHead and Neck squamous cell carcinoma518 0.8830.534NS
KIRCKidney renal clear cell carcinoma531 0.3716.63e-06Longer
KIRPKidney renal papillary cell carcinoma287 0.7670.548NS
LAMLAcute Myeloid Leukemia149 0.550.039Longer
LGGBrain Lower Grade Glioma511 0.3441.7e-05Longer
LIHCLiver hepatocellular carcinoma365 0.9590.868NS
LUADLung adenocarcinoma502 1.040.856NS
LUSCLung squamous cell carcinoma494 1.0430.831NS
OVOvarian serous cystadenocarcinoma303 0.9210.707NS
PAADPancreatic adenocarcinoma177 1.0610.836NS
PCPGPheochromocytoma and Paraganglioma179 1432244100.1150.106NS
PRADProstate adenocarcinoma497 2.2480.574NS
READRectum adenocarcinoma159 0.3090.0631NS
SARCSarcoma259 0.8440.56NS
SKCMSkin Cutaneous Melanoma459 1.320.149NS
STADStomach adenocarcinoma388 1.0120.958NS
TGCTTesticular Germ Cell Tumors134 1.1590.917NS
THCAThyroid carcinoma500 1.1850.792NS
THYMThymoma119 1.2440.79NS
UCECUterine Corpus Endometrial Carcinoma543 1.2940.413NS
> Stage
 

  Association between expresson and stage.
Cancer Full Name # Patients R Value (Spearman) P Value (Spearman) Association
BLCABladder urothelial carcinoma406 -0.1010.0427Lower
BRCABreast invasive carcinoma1071 0.0170.571NS
CESCCervical and endocervical cancers167 0.1130.147NS
COADColon adenocarcinoma445 -0.0510.284NS
ESCAEsophageal carcinoma162 0.0130.871NS
HNSCHead and Neck squamous cell carcinoma448 -0.0170.723NS
KIRCKidney renal clear cell carcinoma531 -0.183.11e-05Lower
KIRPKidney renal papillary cell carcinoma260 0.0730.243NS
LIHCLiver hepatocellular carcinoma347 0.0670.215NS
LUADLung adenocarcinoma507 0.0190.668NS
LUSCLung squamous cell carcinoma497 0.0030.941NS
OVOvarian serous cystadenocarcinoma302 -0.0060.924NS
PAADPancreatic adenocarcinoma176 0.0420.581NS
READRectum adenocarcinoma156 -0.020.805NS
SKCMSkin Cutaneous Melanoma410 -0.0310.527NS
STADStomach adenocarcinoma392 0.040.424NS
TGCTTesticular Germ Cell Tumors81 -0.2070.0637NS
THCAThyroid carcinoma499 0.0090.833NS
UCECUterine Corpus Endometrial Carcinoma501 -0.0220.622NS
> Grade
 

  Association between expresson and grade.
Cancer Full Name # Patients R Value (Spearman) P Value (Spearman) Association
CESCCervical and endocervical cancers272 -0.1490.0141Lower
HNSCHead and Neck squamous cell carcinoma498 0.1160.00934Higher
KIRCKidney renal clear cell carcinoma525 -0.1650.000139Lower
LGGBrain Lower Grade Glioma514 -0.1340.00227Lower
LIHCLiver hepatocellular carcinoma366 0.1290.0136Higher
OVOvarian serous cystadenocarcinoma296 0.0510.383NS
PAADPancreatic adenocarcinoma176 0.0580.447NS
STADStomach adenocarcinoma406 0.0290.556NS
UCECUterine Corpus Endometrial Carcinoma534 0.080.0658NS
Summary
SymbolKDM3B
Namelysine demethylase 3B
Aliases KIAA1082; NET22; C5orf7; JMJD1B; chromosome 5 open reading frame 7; jumonji domain containing 1B; 5qNCA; jmj ......
Location5q31.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Targets inferred by reverse engineering method
> Targets identified by ChIP-seq data
> Targets inferred by reverse engineering method
 
> Targets identified by ChIP-seq data
 
Summary
SymbolKDM3B
Namelysine demethylase 3B
Aliases KIAA1082; NET22; C5orf7; JMJD1B; chromosome 5 open reading frame 7; jumonji domain containing 1B; 5qNCA; jmj ......
Location5q31.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Drugs from DrugBank database
> Drugs from DrugBank database
 
There is no record for KDM3B.
Summary
SymbolKDM3B
Namelysine demethylase 3B
Aliases KIAA1082; NET22; C5orf7; JMJD1B; chromosome 5 open reading frame 7; jumonji domain containing 1B; 5qNCA; jmj ......
Location5q31.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Protein-Protein Interaction Network
> miRNA Regulatory Relationship
> Interactions from Text Mining
> Protein-Protein Interaction Network
 
> miRNA Regulatory Relationship
 
> Interactions from Text Mining
 
There is no record for KDM3B.