Browse LMNB1 in pancancer

Summary
SymbolLMNB1
Namelamin B1
Aliases ADLD; LMN; LMNB; Lamin-B1
Location5q23.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Domain, Function and Classification
> Gene Ontology
> KEGG and Reactome Pathway
> Domain, Function and Classification
 
Domain PF00038 Intermediate filament protein
PF00932 Lamin Tail Domain
Function

Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.

Classification
Class Modification Substrate Product PubMed
# # # # #
> Gene Ontology
 
Biological Process -
Molecular Function GO:0043274 phospholipase binding
Cellular Component GO:0005635 nuclear envelope
GO:0005637 nuclear inner membrane
GO:0005638 lamin filament
GO:0005652 nuclear lamina
GO:0005882 intermediate filament
GO:0016363 nuclear matrix
GO:0031965 nuclear membrane
GO:0034399 nuclear periphery
GO:0045111 intermediate filament cytoskeleton
> KEGG and Reactome Pathway
 
KEGG hsa04210 Apoptosis
Reactome R-HSA-109581: Apoptosis
R-HSA-111465: Apoptotic cleavage of cellular proteins
R-HSA-75153: Apoptotic execution phase
R-HSA-352238: Breakdown of the nuclear lamina
R-HSA-1640170: Cell Cycle
R-HSA-69278: Cell Cycle, Mitotic
R-HSA-2559583: Cellular Senescence
R-HSA-2262752: Cellular responses to stress
R-HSA-2559586: DNA Damage/Telomere Stress Induced Senescence
R-HSA-4419969: Depolymerisation of the Nuclear Lamina
R-HSA-8862803: Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
R-HSA-1643685: Disease
R-HSA-2559584: Formation of Senescence-Associated Heterochromatin Foci (SAHF)
R-HSA-2995383: Initiation of Nuclear Envelope Reformation
R-HSA-68886: M Phase
R-HSA-1500620: Meiosis
R-HSA-1221632: Meiotic synapsis
R-HSA-68882: Mitotic Anaphase
R-HSA-2555396: Mitotic Metaphase and Anaphase
R-HSA-68875: Mitotic Prophase
R-HSA-8863678: Neurodegenerative Diseases
R-HSA-2980766: Nuclear Envelope Breakdown
R-HSA-2995410: Nuclear Envelope Reassembly
R-HSA-5357801: Programmed Cell Death
Summary
SymbolLMNB1
Namelamin B1
Aliases ADLD; LMN; LMNB; Lamin-B1
Location5q23.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Mutation landscape in primary tumor tissue from TCGA
> Mutation landscape in cancer cell line from CCLE
> All mutations from COSMIC database V81
> Variations from text mining
> The Cancer Genome Atlas (TCGA)
 
> Cancer Cell Line Encyclopedia (CCLE)
 
> Catalogue of Somatic Mutations in Cancer (COSMIC)
 
COSMIC ID CDS change AA change Mutation Type Anatomical Site
COSM4761088c.925A>Cp.N309HSubstitution - MissenseStomach
COSM176391c.1010G>Ap.R337HSubstitution - MissenseLarge_intestine
COSM5834921c.1114delAp.M372fs*10Deletion - FrameshiftBreast
COSM3849778c.1228C>Tp.R410CSubstitution - MissenseStomach
COSM4698233c.1025_1026insAGp.M346fs*5Insertion - FrameshiftLarge_intestine
COSM1186820c.298C>Ap.R100SSubstitution - MissenseLung
COSM5481921c.1003T>Cp.S335PSubstitution - MissenseLarge_intestine
COSM4698237c.1559C>Tp.S520LSubstitution - MissenseLarge_intestine
COSM124127c.605C>Tp.T202ISubstitution - MissenseUpper_aerodigestive_tract
COSM4585360c.1536C>Tp.D512DSubstitution - coding silentBone
COSM1166751c.548_551delAGTTp.L184fs*8Deletion - FrameshiftHaematopoietic_and_lymphoid_tissue
COSM1239337c.939+2T>Cp.?UnknownOesophagus
COSM1213489c.468A>Cp.K156NSubstitution - MissenseLarge_intestine
COSM40261c.205G>Ap.E69KSubstitution - MissenseCentral_nervous_system
COSM5812973c.932A>Tp.Q311LSubstitution - MissenseLiver
COSM4769354c.269G>Ap.R90QSubstitution - MissenseBiliary_tract
COSM5896767c.519G>Tp.L173FSubstitution - MissenseSkin
COSM4159382c.1379C>Tp.S460FSubstitution - MissenseThyroid
COSM4433310c.1192G>Ap.V398MSubstitution - MissenseOesophagus
COSM5503003c.481G>Ap.G161RSubstitution - MissenseBiliary_tract
COSM116746c.1700A>Gp.E567GSubstitution - MissenseOvary
COSM1060222c.675G>Ap.T225TSubstitution - coding silentLung
COSM1213487c.1006C>Tp.R336CSubstitution - MissenseLarge_intestine
COSM4524593c.1280G>Tp.S427ISubstitution - MissenseSkin
COSM4960324c.1021G>Ap.D341NSubstitution - MissenseLiver
COSM5039336c.813+1G>Ap.?UnknownLiver
COSM3849780c.1662G>Ap.E554ESubstitution - coding silentBone
COSM5474757c.549G>Ap.Q183QSubstitution - coding silentLarge_intestine
COSM1432772c.469A>Cp.K157QSubstitution - MissenseLarge_intestine
COSM3365793c.980T>Cp.L327SSubstitution - MissenseKidney
COSM4698231c.436G>Tp.D146YSubstitution - MissenseLarge_intestine
COSM1696123c.1672G>Ap.E558KSubstitution - MissenseSkin
COSM448518c.786G>Cp.E262DSubstitution - MissenseBreast
COSM1633899c.1560G>Ap.S520SSubstitution - coding silentLiver
COSM1060226c.1732G>Ap.A578TSubstitution - MissenseEndometrium
COSM3728764c.1204C>Tp.R402*Substitution - NonsenseStomach
COSM5781084c.695C>Ap.S232YSubstitution - MissenseBreast
COSM4942371c.709G>Tp.E237*Substitution - NonsenseLiver
COSM1060223c.1247G>Tp.R416LSubstitution - MissenseEndometrium
COSM1060222c.675G>Ap.T225TSubstitution - coding silentEndometrium
COSM5709441c.1090C>Tp.L364FSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM5996314c.78C>Tp.R26RSubstitution - coding silentProstate
COSM3849780c.1662G>Ap.E554ESubstitution - coding silentStomach
COSM4698236c.1479C>Tp.G493GSubstitution - coding silentLarge_intestine
COSM1671835c.758A>Gp.H253RSubstitution - MissenseBreast
COSM4395494c.1539C>Ap.L513LSubstitution - coding silentSkin
COSM1495935c.1112A>Gp.D371GSubstitution - MissenseKidney
COSM1619373c.1584G>Ap.K528KSubstitution - coding silentLiver
COSM1432775c.1012A>Gp.M338VSubstitution - MissenseLarge_intestine
COSM1432776c.1026_1027delAGp.E345fs*14Deletion - FrameshiftLarge_intestine
COSM1060222c.675G>Ap.T225TSubstitution - coding silentLarge_intestine
COSM1736383c.1225G>Cp.V409LSubstitution - MissenseCentral_nervous_system
COSM481816c.1440C>Tp.V480VSubstitution - coding silentKidney
COSM1060219c.391G>Ap.A131TSubstitution - MissenseEndometrium
COSM5476555c.1671G>Ap.E557ESubstitution - coding silentLarge_intestine
COSM5805278c.1491A>Tp.T497TSubstitution - coding silentLiver
COSM4698234c.1065A>Tp.Q355HSubstitution - MissenseLarge_intestine
COSM4155431c.522A>Cp.E174DSubstitution - MissenseKidney
COSM28370c.111C>Ap.R37RSubstitution - coding silentKidney
COSM4698232c.834A>Gp.S278SSubstitution - coding silentLarge_intestine
COSM5507540c.364G>Ap.A122TSubstitution - MissenseBiliary_tract
COSM5825085c.1011C>Tp.R337RSubstitution - coding silentPancreas
COSM1736384c.1548G>Cp.K516NSubstitution - MissenseCentral_nervous_system
COSM1432778c.1065A>Gp.Q355QSubstitution - coding silentLarge_intestine
COSM1432773c.540_541insAp.Q183fs*5Insertion - FrameshiftLarge_intestine
COSM261790c.465_466insAp.S158fs*30Insertion - FrameshiftLarge_intestine
COSM3776138c.316G>Ap.E106KSubstitution - MissenseUrinary_tract
COSM1060224c.1333G>Ap.E445KSubstitution - MissenseEndometrium
COSM1619373c.1584G>Ap.K528KSubstitution - coding silentLiver
COSM224913c.726_727GG>AAp.L242>?ComplexSkin
COSM1060220c.626A>Cp.K209TSubstitution - MissenseEndometrium
COSM1213488c.464A>Gp.D155GSubstitution - MissenseLarge_intestine
COSM3414543c.1107C>Tp.A369ASubstitution - coding silentOesophagus
COSM3428876c.1593G>Tp.L531FSubstitution - MissenseLarge_intestine
COSM1495933c.1258G>Ap.D420NSubstitution - MissenseKidney
COSM1671836c.1478G>Ap.G493DSubstitution - MissenseLarge_intestine
COSM3393104c.556G>Ap.D186NSubstitution - MissensePancreas
COSM4769354c.269G>Ap.R90QSubstitution - MissenseCervix
COSM1310489c.817G>Cp.E273QSubstitution - MissenseUrinary_tract
COSM1060225c.1558T>Cp.S520PSubstitution - MissenseEndometrium
COSM1432771c.431C>Tp.S144LSubstitution - MissenseLarge_intestine
COSM4698235c.1358T>Gp.F453CSubstitution - MissenseLarge_intestine
COSM3849779c.1349A>Gp.D450GSubstitution - MissenseStomach
COSM4761085c.634T>Cp.Y212HSubstitution - MissenseStomach
COSM4960324c.1021G>Ap.D341NSubstitution - MissenseLiver
COSM3135584c.636T>Cp.Y212YSubstitution - coding silentLarge_intestine
COSM3135588c.1221T>Cp.R407RSubstitution - coding silentStomach
COSM282449c.1036A>Cp.M346LSubstitution - MissenseLarge_intestine
COSM369092c.604A>Tp.T202SSubstitution - MissenseLung
COSM4747854c.95_97delAGAp.K33delKDeletion - In frameStomach
COSM1432777c.1041G>Ap.A347ASubstitution - coding silentLarge_intestine
COSM237665c.1162T>Cp.L388LSubstitution - coding silentProstate
COSM3135586c.863G>Ap.S288NSubstitution - MissenseLarge_intestine
COSM1291999c.1140C>Tp.L380LSubstitution - coding silentHaematopoietic_and_lymphoid_tissue
COSM1060221c.651C>Tp.N217NSubstitution - coding silentEndometrium
COSM1495934c.1254G>Ap.R418RSubstitution - coding silentKidney
> Text Mining based Variations
 
There is no record for LMNB1.
Summary
SymbolLMNB1
Namelamin B1
Aliases ADLD; LMN; LMNB; Lamin-B1
Location5q23.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Post-translational modification (PTM)
> Post-translational modification (PTM)
 
 Filter By:
Uniprot ID Position Amino Acid Description Upstream Enzyme Affected By Mutation Amino Acid Sequence Variant
P207003TPhosphothreonine-NoNone detected
P207005TPhosphothreonine-NoNone detected
P2070014ROmega-N-methylarginine-NoNone detected
P2070020TPhosphothreonine-NoNone detected
P2070023SPhosphoserine-NoNone detected
P2070025TPhosphothreonine-NoNone detected
P2070028SPhosphoserine-NoNone detected
P20700111KN6-acetyllysine-NoNone detected
P20700126SPhosphoserine-NoNone detected
P20700157KN6-acetyllysine-Yesp.K157Q (cancer: COAD); p.K157fs (cancer: STAD)
P20700158SPhosphoserine-NoNone detected
P20700200SPhosphoserine-NoNone detected
P20700210SPhosphoserine-NoNone detected
P20700232SPhosphoserine-NoNone detected
P20700271KN6-acetyllysine-NoNone detected
P20700278SPhosphoserine-NoNone detected
P20700302SPhosphoserine-NoNone detected
P20700330KN6-acetyllysine-NoNone detected
P20700375SPhosphoserine-NoNone detected
P20700413ROmega-N-methylarginine-NoNone detected
P20700483KN6-acetyllysine-NoNone detected
P20700534SPhosphoserine-NoNone detected
P20700575TPhosphothreonine-NoNone detected
P20700583CCysteine methyl ester-NoNone detected
Summary
SymbolLMNB1
Namelamin B1
Aliases ADLD; LMN; LMNB; Lamin-B1
Location5q23.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Expression analysis in primary tumor tissue from TCGA
> Expression level in cancer cell line from CCLE
> Expression level in human normal tissue from HPA
> Text mining based expression change
> The Cancer Genome Atlas (TCGA)
 


  Differential expression analysis for cancers with more than 10 normal samples
Cancer Full Name # N # T Median (N) Median (T) LogFC Adj. P Status
BLCABladder urothelial carcinoma194083.9246.1142.0811.77e-17Over
BRCABreast invasive carcinoma11211003.3965.8592.475.79e-109Over
CESCCervical and endocervical cancers33063.0857.055NANANA
COADColon adenocarcinoma414595.9696.6660.6341.65e-10Over
ESCAEsophageal carcinoma111852.8695.8352.4148.32e-17Over
GBMGlioblastoma multiforme51662.0635.815NANANA
HNSCHead and Neck squamous cell carcinoma445225.25.7650.8711.79e-09Over
KIRCKidney renal clear cell carcinoma725342.3584.0481.446.63e-36Over
KIRPKidney renal papillary cell carcinoma322911.9923.1611.071.23e-08Over
LAMLAcute Myeloid Leukemia0173NA7.151NANANA
LGGBrain Lower Grade Glioma0530NA4.372NANANA
LIHCLiver hepatocellular carcinoma503733.0014.1260.9786.46e-08Over
LUADLung adenocarcinoma595173.5685.3071.7531.15e-36Over
LUSCLung squamous cell carcinoma515013.8066.0322.1141.83e-66Over
OVOvarian serous cystadenocarcinoma0307NA6.056NANANA
PAADPancreatic adenocarcinoma41794.2984.746NANANA
PCPGPheochromocytoma and Paraganglioma31841.3022.301NANANA
PRADProstate adenocarcinoma524982.6853.6110.8716.83e-10Over
READRectum adenocarcinoma101676.0026.6190.6330.00733Over
SARCSarcoma22632.5595.684NANANA
SKCMSkin Cutaneous Melanoma14726.3675.5NANANA
STADStomach adenocarcinoma354155.1166.0391.7261.24e-19Over
TGCTTesticular Germ Cell Tumors0156NA6.934NANANA
THCAThyroid carcinoma595092.4163.4020.5642.39e-06NS
THYMThymoma21207.1727.006NANANA
UCECUterine Corpus Endometrial Carcinoma355463.6896.4382.8115.42e-53Over
> Cancer Cell Line Encyclopedia (CCLE)
 



Tissue Cell Line Expression Level (Microarray)
Autonomic ganglia CHP126 10
Autonomic ganglia CHP212 10.3
Autonomic ganglia IMR32 10.8
Autonomic ganglia KELLY 11.3
Autonomic ganglia KPNRTBM1 9.5
Autonomic ganglia KPNSI9S 9.5
Autonomic ganglia KPNYN 10.1
Autonomic ganglia MHHNB11 8.2
Autonomic ganglia NB1 10.4
Autonomic ganglia NH6 9.2
Autonomic ganglia SHSY5Y 9.1
Autonomic ganglia SIMA 10.3
Autonomic ganglia SKNAS 8.9
Autonomic ganglia SKNBE2 9.8
Autonomic ganglia SKNDZ 10.3
Autonomic ganglia SKNFI 9.5
Autonomic ganglia SKNSH 8.6
Biliary tract HUCCT1 10.6
Biliary tract HUH28 8.2
Biliary tract SNU1079 9.1
Biliary tract SNU1196 9.7
Biliary tract SNU245 9.7
Biliary tract SNU308 9.3
Biliary tract SNU478 9.9
Bone 143B 9.5
Bone A673 10.6
Bone CADOES1 9.6
Bone CAL78 9.6
Bone G292CLONEA141B1 9.3
Bone HOS 9.4
Bone HS706T 8.4
Bone HS737T 6
Bone HS819T 5.8
Bone HS821T 8.1
Bone HS822T 4.9
Bone HS863T 8.4
Bone HS870T 7.9
Bone HS888T 8.9
Bone MG63 10.1
Bone MHHES1 9.7
Bone OUMS27 7.7
Bone RDES 9.9
Bone SJSA1 10.2
Bone SKES1 9.9
Bone SKNMC 11
Bone SW1353 8.1
Bone T173 7.3
Bone TC71 9.2
Bone U2OS 11.3
Breast AU565 8.9
Breast BT20 10.1
Breast BT474 10.8
Breast BT483 9.8
Breast BT549 10.5
Breast CAL120 10.1
Breast CAL148 10.8
Breast CAL51 11.1
Breast CAL851 10.7
Breast CAMA1 9.8
Breast DU4475 9.5
Breast EFM192A 11
Breast EFM19 10.7
Breast EVSAT 11
Breast HCC1143 11
Breast HCC1187 9.2
Breast HCC1395 9.6
Breast HCC1419 9.8
Breast HCC1428 10.4
Breast HCC1500 9.4
Breast HCC1569 10.6
Breast HCC1599 9.4
Breast HCC1806 9.6
Breast HCC1937 11.4
Breast HCC1954 10
Breast HCC202 9.1
Breast HCC2157 9.5
Breast HCC2218 9.7
Breast HCC38 8.7
Breast HCC70 9.3
Breast HDQP1 9
Breast HMC18 9.7
Breast HS274T 9
Breast HS281T 9
Breast HS343T 9.4
Breast HS578T 9.3
Breast HS606T 8.5
Breast HS739T 6.7
Breast HS742T 4.9
Breast JIMT1 10.1
Breast KPL1 10.4
Breast MCF7 10
Breast MDAMB134VI 9.5
Breast MDAMB157 9.7
Breast MDAMB175VII 8.4
Breast MDAMB231 9
Breast MDAMB361 10.2
Breast MDAMB415 10.5
Breast MDAMB436 9.4
Breast MDAMB453 11.6
Breast MDAMB468 11.2
Breast SKBR3 10.2
Breast T47D 9.3
Breast UACC812 9.5
Breast UACC893 8.7
Breast YMB1 8.3
Breast ZR751 7.4
Breast ZR7530 9.9
Central nervous system 1321N1 12.3
Central nervous system 42MGBA 11.1
Central nervous system 8MGBA 10.3
Central nervous system A172 9.8
Central nervous system AM38 10
Central nervous system BECKER 8.4
Central nervous system CAS1 8.2
Central nervous system CCFSTTG1 9.4
Central nervous system D283MED 12
Central nervous system D341MED 8.1
Central nervous system DAOY 10.8
Central nervous system DBTRG05MG 10
Central nervous system DKMG 8.9
Central nervous system GAMG 10.3
Central nervous system GB1 11
Central nervous system GI1 9.5
Central nervous system GMS10 10.6
Central nervous system GOS3 8.7
Central nervous system H4 9.4
Central nervous system HS683 9.2
Central nervous system KALS1 8.8
Central nervous system KG1C 7.2
Central nervous system KNS42 9.8
Central nervous system KNS60 9.6
Central nervous system KNS81 9
Central nervous system KS1 10.7
Central nervous system LN18 11.3
Central nervous system LN229 9.7
Central nervous system M059K 9.6
Central nervous system MOGGCCM 10.9
Central nervous system MOGGUVW 10.8
Central nervous system NMCG1 9.4
Central nervous system ONS76 9.2
Central nervous system SF126 9
Central nervous system SF295 8.9
Central nervous system SNB19 10.9
Central nervous system SNU1105 8.9
Central nervous system SNU201 8.8
Central nervous system SNU466 8.8
Central nervous system SNU489 7.6
Central nervous system SNU626 9.4
Central nervous system SNU738 10.1
Central nervous system SW1088 8.8
Central nervous system SW1783 8.6
Central nervous system T98G 11.1
Central nervous system TM31 8.8
Central nervous system U118MG 8.8
Central nervous system U138MG 8.7
Central nervous system U251MG 9.4
Central nervous system U87MG 9.9
Central nervous system YH13 9.1
Central nervous system YKG1 10
Endometrium AN3CA 11.9
Endometrium COLO684 10.5
Endometrium EFE184 8
Endometrium EN 10.6
Endometrium ESS1 10.6
Endometrium HEC108 8.7
Endometrium HEC151 9.2
Endometrium HEC1A 11.3
Endometrium HEC1B 10.3
Endometrium HEC251 10.8
Endometrium HEC265 9.7
Endometrium HEC50B 10.2
Endometrium HEC59 10.6
Endometrium HEC6 10.4
Endometrium ISHIKAWAHERAKLIO02ER 10.6
Endometrium JHUEM1 9.2
Endometrium JHUEM2 11.2
Endometrium JHUEM3 9.5
Endometrium KLE 8.4
Endometrium MFE280 9.7
Endometrium MFE296 10.1
Endometrium MFE319 8.9
Endometrium RL952 9.2
Endometrium SNGM 8.9
Endometrium SNU1077 9.6
Endometrium SNU685 9.5
Endometrium TEN 10.8
Haematopoietic and lymphoid 697 11.9
Haematopoietic and lymphoid A3KAW 10.2
Haematopoietic and lymphoid A4FUK 10.2
Haematopoietic and lymphoid ALLSIL 11.5
Haematopoietic and lymphoid AML193 10.5
Haematopoietic and lymphoid AMO1 10.2
Haematopoietic and lymphoid BCP1 9.3
Haematopoietic and lymphoid BDCM 11.2
Haematopoietic and lymphoid BL41 11
Haematopoietic and lymphoid BL70 10.8
Haematopoietic and lymphoid BV173 11
Haematopoietic and lymphoid CA46 9.1
Haematopoietic and lymphoid CI1 10.2
Haematopoietic and lymphoid CMK115 10.7
Haematopoietic and lymphoid CMK86 10.8
Haematopoietic and lymphoid CMK 10.5
Haematopoietic and lymphoid CMLT1 10.5
Haematopoietic and lymphoid COLO775 9.5
Haematopoietic and lymphoid DAUDI 10
Haematopoietic and lymphoid DB 9.8
Haematopoietic and lymphoid DEL 11.7
Haematopoietic and lymphoid DND41 11.2
Haematopoietic and lymphoid DOHH2 10.9
Haematopoietic and lymphoid EB1 10.2
Haematopoietic and lymphoid EB2 9.5
Haematopoietic and lymphoid EHEB 9.6
Haematopoietic and lymphoid EJM 9.8
Haematopoietic and lymphoid EM2 10.7
Haematopoietic and lymphoid EOL1 11.2
Haematopoietic and lymphoid F36P 10.2
Haematopoietic and lymphoid GA10 10.9
Haematopoietic and lymphoid GDM1 9.7
Haematopoietic and lymphoid GRANTA519 10.2
Haematopoietic and lymphoid HDLM2 10.4
Haematopoietic and lymphoid HDMYZ 10.8
Haematopoietic and lymphoid HEL9217 10.5
Haematopoietic and lymphoid HEL 9.9
Haematopoietic and lymphoid HH 10.9
Haematopoietic and lymphoid HL60 11.6
Haematopoietic and lymphoid HPBALL 11.4
Haematopoietic and lymphoid HS604T 7.7
Haematopoietic and lymphoid HS611T 10
Haematopoietic and lymphoid HS616T 6.8
Haematopoietic and lymphoid HS751T 8.9
Haematopoietic and lymphoid HT 10.8
Haematopoietic and lymphoid HTK 10.1
Haematopoietic and lymphoid HUNS1 10.2
Haematopoietic and lymphoid HUT102 9.1
Haematopoietic and lymphoid HUT78 10.2
Haematopoietic and lymphoid JEKO1 10.6
Haematopoietic and lymphoid JK1 10.2
Haematopoietic and lymphoid JM1 10.4
Haematopoietic and lymphoid JURKAT 10.6
Haematopoietic and lymphoid JURLMK1 10.3
Haematopoietic and lymphoid JVM2 10.1
Haematopoietic and lymphoid JVM3 10.2
Haematopoietic and lymphoid K562 11.2
Haematopoietic and lymphoid KARPAS299 11.4
Haematopoietic and lymphoid KARPAS422 9.7
Haematopoietic and lymphoid KARPAS620 11
Haematopoietic and lymphoid KASUMI1 10.7
Haematopoietic and lymphoid KASUMI2 10.8
Haematopoietic and lymphoid KASUMI6 10.2
Haematopoietic and lymphoid KCL22 11
Haematopoietic and lymphoid KE37 11.6
Haematopoietic and lymphoid KE97 10
Haematopoietic and lymphoid KG1 8.9
Haematopoietic and lymphoid KHM1B 9.4
Haematopoietic and lymphoid KIJK 11.4
Haematopoietic and lymphoid KMH2 10.6
Haematopoietic and lymphoid KMM1 10
Haematopoietic and lymphoid KMS11 9.9
Haematopoietic and lymphoid KMS12BM 10.7
Haematopoietic and lymphoid KMS18 10.3
Haematopoietic and lymphoid KMS20 10.1
Haematopoietic and lymphoid KMS21BM 9.5
Haematopoietic and lymphoid KMS26 10.1
Haematopoietic and lymphoid KMS27 10
Haematopoietic and lymphoid KMS28BM 9.3
Haematopoietic and lymphoid KMS34 9.8
Haematopoietic and lymphoid KO52 10.5
Haematopoietic and lymphoid KOPN8 11.2
Haematopoietic and lymphoid KU812 10.5
Haematopoietic and lymphoid KYO1 10.3
Haematopoietic and lymphoid L1236 8.9
Haematopoietic and lymphoid L363 10.9
Haematopoietic and lymphoid L428 11
Haematopoietic and lymphoid L540 9.8
Haematopoietic and lymphoid LAMA84 10.7
Haematopoietic and lymphoid LOUCY 9.5
Haematopoietic and lymphoid LP1 7.1
Haematopoietic and lymphoid M07E 11.3
Haematopoietic and lymphoid MC116 10.8
Haematopoietic and lymphoid ME1 10.9
Haematopoietic and lymphoid MEC1 11.1
Haematopoietic and lymphoid MEC2 10.7
Haematopoietic and lymphoid MEG01 9.6
Haematopoietic and lymphoid MHHCALL2 11.8
Haematopoietic and lymphoid MHHCALL3 11.4
Haematopoietic and lymphoid MHHCALL4 11.1
Haematopoietic and lymphoid MINO 11.1
Haematopoietic and lymphoid MJ 10.5
Haematopoietic and lymphoid MM1S 11.5
Haematopoietic and lymphoid MOLM13 12.2
Haematopoietic and lymphoid MOLM16 10
Haematopoietic and lymphoid MOLM6 9.9
Haematopoietic and lymphoid MOLP2 7
Haematopoietic and lymphoid MOLP8 10.4
Haematopoietic and lymphoid MOLT13 11.6
Haematopoietic and lymphoid MOLT16 11.4
Haematopoietic and lymphoid MOLT4 10.8
Haematopoietic and lymphoid MONOMAC1 11.1
Haematopoietic and lymphoid MONOMAC6 10.6
Haematopoietic and lymphoid MOTN1 10.7
Haematopoietic and lymphoid MUTZ5 11.1
Haematopoietic and lymphoid MV411 12.4
Haematopoietic and lymphoid NALM19 11.4
Haematopoietic and lymphoid NALM1 10.8
Haematopoietic and lymphoid NALM6 11.6
Haematopoietic and lymphoid NAMALWA 10.5
Haematopoietic and lymphoid NB4 11.7
Haematopoietic and lymphoid NCIH929 9
Haematopoietic and lymphoid NCO2 10.1
Haematopoietic and lymphoid NOMO1 11.6
Haematopoietic and lymphoid NUDHL1 9.3
Haematopoietic and lymphoid NUDUL1 11.3
Haematopoietic and lymphoid OCIAML2 10.9
Haematopoietic and lymphoid OCIAML3 10.3
Haematopoietic and lymphoid OCIAML5 10.6
Haematopoietic and lymphoid OCILY10 10
Haematopoietic and lymphoid OCILY19 10.9
Haematopoietic and lymphoid OCILY3 9
Haematopoietic and lymphoid OCIM1 8.7
Haematopoietic and lymphoid OPM2 9.5
Haematopoietic and lymphoid P12ICHIKAWA 11.6
Haematopoietic and lymphoid P31FUJ 9.4
Haematopoietic and lymphoid P3HR1 9.9
Haematopoietic and lymphoid PCM6 9
Haematopoietic and lymphoid PEER 10.1
Haematopoietic and lymphoid PF382 11.4
Haematopoietic and lymphoid PFEIFFER 11.1
Haematopoietic and lymphoid PL21 10.6
Haematopoietic and lymphoid RAJI 9.7
Haematopoietic and lymphoid RCHACV 11.8
Haematopoietic and lymphoid REC1 11
Haematopoietic and lymphoid REH 9.9
Haematopoietic and lymphoid RI1 10.6
Haematopoietic and lymphoid RL 11
Haematopoietic and lymphoid RPMI8226 10.9
Haematopoietic and lymphoid RPMI8402 11.6
Haematopoietic and lymphoid RS411 10.8
Haematopoietic and lymphoid SEM 11.9
Haematopoietic and lymphoid SET2 9.1
Haematopoietic and lymphoid SIGM5 12
Haematopoietic and lymphoid SKM1 9.9
Haematopoietic and lymphoid SKMM2 10.7
Haematopoietic and lymphoid SR786 11.3
Haematopoietic and lymphoid ST486 10.4
Haematopoietic and lymphoid SUDHL10 10.7
Haematopoietic and lymphoid SUDHL1 10.9
Haematopoietic and lymphoid SUDHL4 10.5
Haematopoietic and lymphoid SUDHL5 11.7
Haematopoietic and lymphoid SUDHL6 11.5
Haematopoietic and lymphoid SUDHL8 11.4
Haematopoietic and lymphoid SUPB15 10.8
Haematopoietic and lymphoid SUPHD1 10.2
Haematopoietic and lymphoid SUPM2 11.5
Haematopoietic and lymphoid SUPT11 9.6
Haematopoietic and lymphoid SUPT1 10.7
Haematopoietic and lymphoid TALL1 11.3
Haematopoietic and lymphoid TF1 10.3
Haematopoietic and lymphoid THP1 9.2
Haematopoietic and lymphoid TO175T 8.1
Haematopoietic and lymphoid TOLEDO 10.1
Haematopoietic and lymphoid U266B1 8.5
Haematopoietic and lymphoid U937 8.8
Haematopoietic and lymphoid UT7 8.9
Haematopoietic and lymphoid WSUDLCL2 10.7
Kidney 769P 10.5
Kidney 786O 10.8
Kidney A498 8.3
Kidney A704 7.9
Kidney ACHN 9.6
Kidney BFTC909 10.5
Kidney CAKI1 8.1
Kidney CAKI2 11.3
Kidney CAL54 8.3
Kidney KMRC1 11
Kidney KMRC20 9.5
Kidney KMRC2 10.6
Kidney KMRC3 7.6
Kidney OSRC2 9.2
Kidney RCC10RGB 8.4
Kidney SNU1272 9.2
Kidney SNU349 9.8
Kidney TUHR10TKB 9.6
Kidney TUHR14TKB 7.7
Kidney TUHR4TKB 9.2
Kidney VMRCRCW 8.1
Kidney VMRCRCZ 10.7
Large intestine C2BBE1 9.1
Large intestine CCK81 9.8
Large intestine CL11 10.1
Large intestine CL14 8.5
Large intestine CL34 10
Large intestine CL40 9
Large intestine COLO205 10.1
Large intestine COLO320 9.9
Large intestine COLO678 10.3
Large intestine CW2 10.5
Large intestine DLD1 10.9
Large intestine GP2D 9.6
Large intestine HCC56 9.6
Large intestine HCT116 11.1
Large intestine HCT15 10.1
Large intestine HS675T 6.8
Large intestine HS698T 7.9
Large intestine HT115 9.6
Large intestine HT29 11.5
Large intestine HT55 9.5
Large intestine KM12 10.4
Large intestine LOVO 11.4
Large intestine LS1034 10.7
Large intestine LS123 9.3
Large intestine LS180 10.9
Large intestine LS411N 11.3
Large intestine LS513 10.5
Large intestine MDST8 9.1
Large intestine NCIH508 7
Large intestine NCIH716 9.3
Large intestine NCIH747 11.2
Large intestine OUMS23 8.5
Large intestine RCM1 8.5
Large intestine RKO 8.3
Large intestine SKCO1 9.9
Large intestine SNU1040 10.1
Large intestine SNU1197 9.3
Large intestine SNU175 10.5
Large intestine SNU283 9.3
Large intestine SNU407 9.5
Large intestine SNU503 9.5
Large intestine SNU61 8.9
Large intestine SNU81 9.2
Large intestine SNUC1 9.2
Large intestine SNUC2A 8.5
Large intestine SNUC4 10.6
Large intestine SNUC5 9.6
Large intestine SW1116 9.4
Large intestine SW1417 9.7
Large intestine SW1463 9.9
Large intestine SW403 10.7
Large intestine SW480 9
Large intestine SW48 10.8
Large intestine SW620 11.4
Large intestine SW837 11
Large intestine SW948 9.5
Large intestine T84 11.3
Liver ALEXANDERCELLS 9.2
Liver C3A 8.8
Liver HEP3B217 10.4
Liver HEPG2 9.9
Liver HLE 10.6
Liver HLF 9.6
Liver HUH1 10.5
Liver HUH6 10
Liver HUH7 9.2
Liver JHH1 8.3
Liver JHH2 9.7
Liver JHH4 10
Liver JHH5 9.7
Liver JHH6 9.9
Liver JHH7 9.8
Liver LI7 10.3
Liver PLCPRF5 8.5
Liver SKHEP1 10.3
Liver SNU182 8.5
Liver SNU387 9.2
Liver SNU398 10.7
Liver SNU423 9.4
Liver SNU449 8.7
Liver SNU475 10.8
Liver SNU761 8.2
Liver SNU878 9.9
Liver SNU886 10
Lung A549 10.4
Lung ABC1 10.4
Lung BEN 9.4
Lung CAL12T 10
Lung CALU1 11.2
Lung CALU3 10.4
Lung CALU6 9.9
Lung CHAGOK1 10.6
Lung COLO668 10.3
Lung COLO699 9.4
Lung CORL105 9.2
Lung CORL23 9.7
Lung CORL24 10.9
Lung CORL279 10.1
Lung CORL311 10.2
Lung CORL47 10.9
Lung CORL51 10
Lung CORL88 10.5
Lung CORL95 10.7
Lung CPCN 10.5
Lung DMS114 9.8
Lung DMS153 9.4
Lung DMS273 10.3
Lung DMS454 9.7
Lung DMS53 9.1
Lung DMS79 11
Lung DV90 9.7
Lung EBC1 9.7
Lung EPLC272H 9.2
Lung HARA 9.9
Lung HCC1171 9.5
Lung HCC1195 9.6
Lung HCC15 10.2
Lung HCC2279 8.4
Lung HCC2935 9.6
Lung HCC33 10.7
Lung HCC366 9.6
Lung HCC4006 10.5
Lung HCC44 9.6
Lung HCC78 11.3
Lung HCC827 10
Lung HCC95 10.6
Lung HLC1 8.7
Lung HLFA 8.9
Lung HS229T 9.2
Lung HS618T 8.1
Lung IALM 9.2
Lung KNS62 9.2
Lung LC1F 10.6
Lung LC1SQSF 10.9
Lung LCLC103H 9.3
Lung LCLC97TM1 9.9
Lung LK2 11.3
Lung LOUNH91 10.3
Lung LU65 9.5
Lung LU99 11
Lung LUDLU1 9.6
Lung LXF289 8
Lung MORCPR 9.5
Lung NCIH1048 10.5
Lung NCIH1092 10.6
Lung NCIH1105 11
Lung NCIH1155 11.7
Lung NCIH1184 10.6
Lung NCIH1299 11.6
Lung NCIH1339 9.8
Lung NCIH1341 9.7
Lung NCIH1355 9.2
Lung NCIH1373 9.2
Lung NCIH1385 9.1
Lung NCIH1395 9.4
Lung NCIH1435 9.7
Lung NCIH1436 11
Lung NCIH1437 10.6
Lung NCIH146 10.9
Lung NCIH1563 8.3
Lung NCIH1568 9.1
Lung NCIH1573 8.4
Lung NCIH1581 10.5
Lung NCIH1618 9.6
Lung NCIH1623 9.2
Lung NCIH1648 8.4
Lung NCIH1650 9
Lung NCIH1651 8.7
Lung NCIH1666 8.4
Lung NCIH1693 9.2
Lung NCIH1694 10
Lung NCIH1703 11.2
Lung NCIH1734 9.2
Lung NCIH1755 9
Lung NCIH1781 10.8
Lung NCIH1792 9.7
Lung NCIH1793 9
Lung NCIH1836 9.6
Lung NCIH1838 8.5
Lung NCIH1869 10.8
Lung NCIH1876 10.5
Lung NCIH1915 8.7
Lung NCIH1930 9.1
Lung NCIH1944 9.7
Lung NCIH1963 9.6
Lung NCIH196 10.4
Lung NCIH1975 10.4
Lung NCIH2009 10.5
Lung NCIH2023 8.9
Lung NCIH2029 10.4
Lung NCIH2030 10.4
Lung NCIH2066 9.4
Lung NCIH2081 10.3
Lung NCIH2085 8.7
Lung NCIH2087 10.1
Lung NCIH209 9.4
Lung NCIH2106 10
Lung NCIH2110 9.9
Lung NCIH211 11.5
Lung NCIH2122 10.8
Lung NCIH2126 8.1
Lung NCIH2141 10.5
Lung NCIH2170 10.6
Lung NCIH2171 11
Lung NCIH2172 9.6
Lung NCIH2196 10.8
Lung NCIH2227 8.5
Lung NCIH2228 9.2
Lung NCIH226 8.9
Lung NCIH2286 10.3
Lung NCIH2291 8.4
Lung NCIH2342 8.8
Lung NCIH2347 9.1
Lung NCIH23 8.7
Lung NCIH2405 9.7
Lung NCIH2444 10.3
Lung NCIH292 8.8
Lung NCIH322 8.3
Lung NCIH3255 9.6
Lung NCIH358 10.6
Lung NCIH441 11.4
Lung NCIH446 11.6
Lung NCIH460 9.9
Lung NCIH510 9.6
Lung NCIH520 10.9
Lung NCIH522 10.2
Lung NCIH524 10.2
Lung NCIH526 11.4
Lung NCIH596 9.5
Lung NCIH647 10.9
Lung NCIH650 8.5
Lung NCIH661 10.9
Lung NCIH69 10.4
Lung NCIH727 10.3
Lung NCIH810 9.7
Lung NCIH82 10.7
Lung NCIH838 9.2
Lung NCIH841 10.9
Lung NCIH854 8.9
Lung NCIH889 11
Lung PC14 10
Lung RERFLCAD1 10.9
Lung RERFLCAD2 8.5
Lung RERFLCAI 9.4
Lung RERFLCKJ 7.1
Lung RERFLCMS 9.1
Lung RERFLCSQ1 10.4
Lung SBC5 10.5
Lung SCLC21H 10.8
Lung SHP77 10.7
Lung SKLU1 9.5
Lung SKMES1 9.1
Lung SQ1 11.3
Lung SW1271 11.2
Lung SW1573 10.8
Lung SW900 8.5
Lung VMRCLCD 10.5
Lung VMRCLCP 8.8
Oesophagus COLO680N 7.5
Oesophagus ECGI10 6.9
Oesophagus KYSE140 9.6
Oesophagus KYSE150 11.1
Oesophagus KYSE180 9.6
Oesophagus KYSE270 10.2
Oesophagus KYSE30 9.9
Oesophagus KYSE410 10.6
Oesophagus KYSE450 8
Oesophagus KYSE510 11.7
Oesophagus KYSE520 10.1
Oesophagus KYSE70 9.1
Oesophagus OE19 10.3
Oesophagus OE33 10.1
Oesophagus TE10 10
Oesophagus TE11 11.3
Oesophagus TE14 8.5
Oesophagus TE15 11.2
Oesophagus TE1 9.7
Oesophagus TE4 9.5
Oesophagus TE5 9.4
Oesophagus TE6 10.2
Oesophagus TE8 9.2
Oesophagus TE9 9.1
Oesophagus TT 9
Ovary 59M 9.3
Ovary A2780 12.5
Ovary CAOV3 10.6
Ovary CAOV4 8.4
Ovary COLO704 11.3
Ovary COV318 9
Ovary COV362 9.9
Ovary COV434 10.8
Ovary COV504 9
Ovary COV644 9.8
Ovary EFO21 10.4
Ovary EFO27 9.8
Ovary ES2 10.6
Ovary FUOV1 10.4
Ovary HEYA8 11.1
Ovary HS571T 7
Ovary IGROV1 10.8
Ovary JHOC5 9.6
Ovary JHOM1 7.3
Ovary JHOM2B 10
Ovary JHOS2 9.2
Ovary JHOS4 7.9
Ovary KURAMOCHI 8.2
Ovary MCAS 11.1
Ovary NIHOVCAR3 9
Ovary OAW28 9.8
Ovary OAW42 10.5
Ovary OC314 9.1
Ovary OC316 9
Ovary ONCODG1 10.2
Ovary OV56 8.2
Ovary OV7 10.1
Ovary OV90 9.4
Ovary OVCAR4 9.6
Ovary OVCAR8 10.9
Ovary OVISE 9.3
Ovary OVK18 9.4
Ovary OVKATE 10.4
Ovary OVMANA 9.3
Ovary OVSAHO 10.9
Ovary OVTOKO 9
Ovary RMGI 9.2
Ovary RMUGS 9.2
Ovary SKOV3 9.4
Ovary SNU119 9.8
Ovary SNU840 10.4
Ovary SNU8 10.3
Ovary TOV112D 11
Ovary TOV21G 9.9
Ovary TYKNU 10.8
Pancreas ASPC1 9.3
Pancreas BXPC3 8.9
Pancreas CAPAN1 8.8
Pancreas CAPAN2 11
Pancreas CFPAC1 9.3
Pancreas DANG 8.9
Pancreas HPAC 9.7
Pancreas HPAFII 9.8
Pancreas HS766T 10.4
Pancreas HUPT3 9.1
Pancreas HUPT4 11.2
Pancreas KCIMOH1 10.6
Pancreas KLM1 10.7
Pancreas KP2 11.8
Pancreas KP3 9.4
Pancreas KP4 9.8
Pancreas L33 10.6
Pancreas MIAPACA2 11.4
Pancreas PANC0203 10.2
Pancreas PANC0213 7.8
Pancreas PANC0327 11.2
Pancreas PANC0403 10.5
Pancreas PANC0504 8.7
Pancreas PANC0813 9.5
Pancreas PANC1005 11.3
Pancreas PANC1 9.1
Pancreas PATU8902 10.3
Pancreas PATU8988S 9.2
Pancreas PATU8988T 11.1
Pancreas PK1 9.7
Pancreas PK45H 10.1
Pancreas PK59 9.7
Pancreas PL45 9.8
Pancreas PSN1 10.7
Pancreas QGP1 11.1
Pancreas SNU213 9.3
Pancreas SNU324 9.9
Pancreas SNU410 9.3
Pancreas SU8686 8.4
Pancreas SUIT2 10.2
Pancreas SW1990 8.5
Pancreas T3M4 9.9
Pancreas TCCPAN2 10.5
Pancreas YAPC 10.7
Pleura ACCMESO1 9.2
Pleura DM3 6.4
Pleura ISTMES1 8.3
Pleura ISTMES2 9.3
Pleura JL1 9.4
Pleura MPP89 8.3
Pleura MSTO211H 8.2
Pleura NCIH2052 9.5
Pleura NCIH2452 8.8
Pleura NCIH28 9.8
Prostate 22RV1 11.4
Prostate DU145 11
Prostate LNCAPCLONEFGC 10.7
Prostate MDAPCA2B 9.5
Prostate NCIH660 9.1
Prostate PC3 10
Prostate VCAP 11.2
Salivary gland A253 11
Salivary gland YD15 10.1
Skin A101D 7.8
Skin A2058 10
Skin A375 11.3
Skin C32 9.6
Skin CHL1 11.1
Skin CJM 7.8
Skin COLO679 10
Skin COLO741 9.1
Skin COLO783 9
Skin COLO792 10
Skin COLO800 9.4
Skin COLO818 9.5
Skin COLO829 8.6
Skin COLO849 10.4
Skin G361 9.4
Skin GRM 10
Skin HMCB 11.5
Skin HS294T 9.2
Skin HS600T 7.2
Skin HS688AT 6.9
Skin HS695T 10
Skin HS839T 7.5
Skin HS852T 9.2
Skin HS895T 6.9
Skin HS934T 9.6
Skin HS936T 8.2
Skin HS939T 8.5
Skin HS940T 7.4
Skin HS944T 10.5
Skin HT144 9.3
Skin IGR1 9.7
Skin IGR37 10.5
Skin IGR39 10.4
Skin IPC298 10
Skin K029AX 9.2
Skin LOXIMVI 10.9
Skin MALME3M 9
Skin MDAMB435S 8.6
Skin MELHO 10.4
Skin MELJUSO 11.4
Skin MEWO 9.8
Skin RPMI7951 10.2
Skin RVH421 7.4
Skin SH4 8.7
Skin SKMEL1 8.4
Skin SKMEL24 9.3
Skin SKMEL28 9
Skin SKMEL2 9.7
Skin SKMEL30 10
Skin SKMEL31 7.9
Skin SKMEL3 10
Skin SKMEL5 10.4
Skin UACC257 10.6
Skin UACC62 8.8
Skin WM115 8.6
Skin WM1799 9.4
Skin WM2664 10.7
Skin WM793 8.6
Skin WM88 9
Skin WM983B 10
Small intestine HUTU80 9.5
Soft tissue A204 10.3
Soft tissue G401 11.1
Soft tissue G402 10.9
Soft tissue GCT 10.9
Soft tissue HS729 8.9
Soft tissue HT1080 9.2
Soft tissue KYM1 10.5
Soft tissue MESSA 9.8
Soft tissue RD 10.7
Soft tissue RH30 11.2
Soft tissue RH41 11.2
Soft tissue RKN 9.1
Soft tissue S117 9.8
Soft tissue SJRH30 11.2
Soft tissue SKLMS1 8.4
Soft tissue SKUT1 9.9
Soft tissue TE125T 7.4
Soft tissue TE159T 6.7
Soft tissue TE441T 11
Soft tissue TE617T 9
Stomach 2313287 9.4
Stomach AGS 11
Stomach AZ521 10.4
Stomach ECC10 10.5
Stomach ECC12 9.1
Stomach FU97 8.5
Stomach GCIY 9
Stomach GSS 8.9
Stomach GSU 9.1
Stomach HGC27 10.5
Stomach HS746T 8.2
Stomach HUG1N 7.9
Stomach IM95 11
Stomach KATOIII 10.3
Stomach KE39 8.6
Stomach LMSU 9.9
Stomach MKN1 10.3
Stomach MKN45 11
Stomach MKN74 8
Stomach MKN7 9.4
Stomach NCCSTCK140 6.3
Stomach NCIN87 11.1
Stomach NUGC2 9
Stomach NUGC3 11
Stomach NUGC4 8.1
Stomach OCUM1 10.3
Stomach RERFGC1B 8.6
Stomach SH10TC 9.9
Stomach SNU16 10.6
Stomach SNU1 9.1
Stomach SNU216 9.8
Stomach SNU520 9.6
Stomach SNU5 10
Stomach SNU601 10.5
Stomach SNU620 8.2
Stomach SNU668 8.9
Stomach SNU719 9.4
Stomach TGBC11TKB 9.5
Thyroid 8305C 9.6
Thyroid 8505C 10.4
Thyroid BCPAP 8.2
Thyroid BHT101 8.4
Thyroid CAL62 10.6
Thyroid CGTHW1 8.9
Thyroid FTC133 9.7
Thyroid FTC238 9.7
Thyroid ML1 9.5
Thyroid SW579 9.9
Thyroid TT2609C02 10.3
Thyroid TT 8.8
Upper aerodigestive tract BHY 8.9
Upper aerodigestive tract BICR16 9
Upper aerodigestive tract BICR18 9.7
Upper aerodigestive tract BICR22 7.7
Upper aerodigestive tract BICR31 9.1
Upper aerodigestive tract BICR56 4.9
Upper aerodigestive tract BICR6 9.1
Upper aerodigestive tract CAL27 10.4
Upper aerodigestive tract CAL33 8.8
Upper aerodigestive tract DETROIT562 10
Upper aerodigestive tract FADU 9.8
Upper aerodigestive tract HS840T 7.9
Upper aerodigestive tract HSC2 8.5
Upper aerodigestive tract HSC3 8.8
Upper aerodigestive tract HSC4 8.6
Upper aerodigestive tract PECAPJ15 9.9
Upper aerodigestive tract PECAPJ34CLONEC12 10.7
Upper aerodigestive tract PECAPJ41CLONED2 9.7
Upper aerodigestive tract PECAPJ49 9.7
Upper aerodigestive tract SCC15 8.4
Upper aerodigestive tract SCC25 9.2
Upper aerodigestive tract SCC4 8.4
Upper aerodigestive tract SCC9 7.3
Upper aerodigestive tract SNU1076 8.9
Upper aerodigestive tract SNU1214 9
Upper aerodigestive tract SNU46 9.6
Upper aerodigestive tract SNU899 9.5
Upper aerodigestive tract YD10B 9.5
Upper aerodigestive tract YD38 10.5
Upper aerodigestive tract YD8 8.5
Urinary tract 5637 9.1
Urinary tract 639V 10.8
Urinary tract 647V 10.2
Urinary tract BC3C 10.3
Urinary tract BFTC905 9.6
Urinary tract CAL29 9.9
Urinary tract HS172T 7.3
Urinary tract HT1197 9.4
Urinary tract HT1376 11.2
Urinary tract J82 9.4
Urinary tract JMSU1 10.5
Urinary tract KMBC2 9.4
Urinary tract KU1919 10
Urinary tract RT11284 10.7
Urinary tract RT112 11.5
Urinary tract RT4 10.7
Urinary tract SCABER 10.2
Urinary tract SW1710 9
Urinary tract SW780 9.6
Urinary tract T24 10.2
Urinary tract TCCSUP 9.4
Urinary tract UMUC1 9.8
Urinary tract UMUC3 9.3
Urinary tract VMCUB1 10.2
> The Human Protein Atlas (HPA)
 


Tissue Expression Level (TPM)
Adipose tissue 5.1
Adrenal gland 1.6
Appendix 37.3
Bone marrow 21.3
Breast 3.5
Cerebral cortex 4
Cervix, uterine 5.5
Colon 15.1
Duodenum 11.8
Endometrium 5
Epididymis 0.6
Esophagus 6.5
Fallopian tube 2.9
Gallbladder 5.5
Heart muscle 0.3
Kidney 1.2
Liver 2.6
Lung 4.9
Lymph node 41.9
Ovary 2.3
Pancreas 0.2
Parathyroid gland 2.2
Placenta 9.6
Prostate 2.2
Rectum 14.8
Salivary gland 0.8
Seminal vesicle 2.3
Skeletal muscle 0.3
Skin 10.3
Small intestine 16.3
Smooth muscle 5.1
Spleen 13
Stomach 7.6
Testis 3.5
Thyroid gland 1.9
Tonsil 27.8
Urinary bladder 6.8
> Text Mining based Expression
 
PMID Expression Cancer Evidence
27449096UnderexpressionGastric CarcinomaFurther expression characterization showed reduced lamin B1 in gastric cancer tissue and cancer cells
24293108UnderexpressionBreast CarcinomaThe expression of LMNB1 declined with worsening clinical outcome (disease-free vs. mortalities - 0.0011 vs. 0.000; p = 0.0177).
23857605OverexpressionPancreatic CarcinomaOverexpression of lamin B1 was pronounced in human pancreatic cancer, and increased lamin B1 expression was directly associated with low-grade differentiation, increased incidence of distant metastasis, and poor prognosis of patients with pancreatic cancer.
22903723OverexpressionHepatocellular CarcinomaCapitalizing our established proteomic platform primarily based on two-dimensional polyacrylamide gel electrophoresis (2DE) and MALDI-TOF/TOF mass spectrometry, our groups have identified lamin B1 (LMNB1) and vimentin (VIM) as promising biomarkers for detection of early HCC. Protein levels of both biomarkers were significantly elevated in cancerous tissues when compared to the controls in disease-free and cirrhotic liver subjects.
19522540OverexpressionHepatocellular CarcinomaWe successfully identified lamin B1 (LMNB1) that was significantly upregulated in HCC tumors and present in patients' plasma
10517909UnderexpressionColon Carcinoma; colon adenoma, Gastric CarcinomaLamin B1 expression was reduced in all colon cancers, 16/18 colonic adenomas, and 6/8 gastric cancers.
Summary
SymbolLMNB1
Namelamin B1
Aliases ADLD; LMN; LMNB; Lamin-B1
Location5q23.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Somatic copy number alteration in primary tomur tissue
> The Cancer Genome Atlas (TCGA)
 


  Correlation between expression and SCNA as well as percentage of patients in different status.
Cancer Full Name # Sample R P % Loss % Neutral % Gain Status
BLCABladder urothelial carcinoma4040.1540.0018547.346.36.4Loss
BRCABreast invasive carcinoma1075-0.0120.70623.656.819.5Neutral
CESCCervical and endocervical cancers2920.3895.18e-1222.968.28.9Neutral
COADColon adenocarcinoma4490.3714.23e-1625.467.76.9Neutral
ESCAEsophageal carcinoma1830.1950.0080352.542.15.5Loss
GBMGlioblastoma multiforme1470.0470.57212.279.68.2Neutral
HNSCHead and Neck squamous cell carcinoma5140.363.84e-1739.753.56.8Loss
KIRCKidney renal clear cell carcinoma5250.0730.09681.34157.7Gain
KIRPKidney renal papillary cell carcinoma2880.1190.04323.883.312.8Neutral
LAMLAcute Myeloid Leukemia1660.3494.02e-068.491.60Neutral
LGGBrain Lower Grade Glioma5130.0080.8599.289.31.6Neutral
LIHCLiver hepatocellular carcinoma3640.0130.80512.456.930.8Neutral
LUADLung adenocarcinoma5120.0370.40739.543.417.2Loss
LUSCLung squamous cell carcinoma4980.0670.13477.120.52.4Loss
OVOvarian serous cystadenocarcinoma3000.3684.47e-1152.336.711Loss
PAADPancreatic adenocarcinoma177-0.1060.16211.97810.2Neutral
PCPGPheochromocytoma and Paraganglioma1620.0990.2116.288.94.9Neutral
PRADProstate adenocarcinoma4910.0720.1138.688.23.3Neutral
READRectum adenocarcinoma1640.4318.08e-0931.157.911Neutral
SARCSarcoma2550.1560.012515.76024.3Neutral
SKCMSkin Cutaneous Melanoma3670.2576.3e-0731.356.712Neutral
STADStomach adenocarcinoma4130.2551.46e-0734.959.16.1Loss
TGCTTesticular Germ Cell Tumors1500.3070.0001356630.73.3Loss
THCAThyroid carcinoma497-0.0020.961096.43.6Neutral
THYMThymoma119-0.1860.04240.891.67.6Neutral
UCECUterine Corpus Endometrial Carcinoma5370.0870.043217.179.53.4Neutral
Summary
SymbolLMNB1
Namelamin B1
Aliases ADLD; LMN; LMNB; Lamin-B1
Location5q23.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Methylation level in the promoter region of CR
> Methylation level in the promoter region of CR
 


  Correlation between expression and methylation as well as differential methylation analysis.
Cancer Full Name R P # N # T Delta beta (T vs N) P value (T vs N) Status
BLCABladder urothelial carcinoma-0.1350.0053817408-0.0520.00408NS/NA
BRCABreast invasive carcinoma-0.1020.002783785-0.0010.0431NS/NA
CESCCervical and endocervical cancers-0.2623.27e-063306NANANS/NA
COADColon adenocarcinoma-0.1380.013919297-0.0120.286NS/NA
ESCAEsophageal carcinoma-0.2230.001829185NANANS/NA
GBMGlioblastoma multiforme-0.2190.0797164NANANS/NA
HNSCHead and Neck squamous cell carcinoma-0.0760.0776205220.0042.31e-05NS/NA
KIRCKidney renal clear cell carcinoma0.0530.3272431900.178NS/NA
KIRPKidney renal papillary cell carcinoma-0.0440.45232750.0040.193NS/NA
LAMLAcute Myeloid Leukemia-0.3065.43e-050170NANANS/NA
LGGBrain Lower Grade Glioma-0.090.03850530NANANS/NA
LIHCLiver hepatocellular carcinoma-0.2371.11e-0641373-0.0866.42e-09NS/NA
LUADLung adenocarcinoma-0.0320.48221456-0.0010.284NS/NA
LUSCLung squamous cell carcinoma-0.2084.6e-058370NANANS/NA
OVOvarian serous cystadenocarcinoma-0.7670.021409NANANS/NA
PAADPancreatic adenocarcinoma-0.1270.08764179NANANS/NA
PCPGPheochromocytoma and Paraganglioma-0.0240.743184NANANS/NA
PRADProstate adenocarcinoma-0.1832.11e-0535498-0.0142.53e-09NS/NA
READRectum adenocarcinoma-0.1650.0994299NANANS/NA
SARCSarcoma-0.1430.020263NANANS/NA
SKCMSkin Cutaneous Melanoma-0.1150.01221471NANANS/NA
STADStomach adenocarcinoma-0.1260.01480372NANANS/NA
TGCTTesticular Germ Cell Tumors-0.332.92e-050156NANANS/NA
THCAThyroid carcinoma-0.140.0009355050900.0638NS/NA
THYMThymoma-0.030.7432120NANANS/NA
UCECUterine Corpus Endometrial Carcinoma-0.0980.034634431-0.0310.0107NS/NA
Summary
SymbolLMNB1
Namelamin B1
Aliases ADLD; LMN; LMNB; Lamin-B1
Location5q23.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Primary tumor tissue from TCGA
> Normal tumor tissue from HPA
>The Cancer Genome Atlas (TCGA)
 
There is no record.
> The Human Protein Atlas (HPA)
 


Tissue Level Level Name
Adrenal gland 3 High
Appendix 3 High
Bone marrow 3 High
Breast 3 High
Bronchus 3 High
Caudate 3 High
Cerebellum 3 High
Cerebral cortex 3 High
Cervix, uterine 3 High
Colon 3 High
Duodenum 3 High
Endometrium 3 High
Epididymis 3 High
Esophagus 3 High
Fallopian tube 3 High
Gallbladder 3 High
Heart muscle 2 Medium
Hippocampus 3 High
Kidney 3 High
Liver 3 High
Lung 3 High
Lymph node 2 Medium
Nasopharynx 3 High
Oral mucosa 3 High
Ovary 2 Medium
Pancreas 3 High
Parathyroid gland 3 High
Placenta 3 High
Prostate 3 High
Rectum 3 High
Salivary gland 3 High
Seminal vesicle 3 High
Skeletal muscle 2 Medium
Skin 3 High
Small intestine 3 High
Smooth muscle 2 Medium
Soft tissue 3 High
Spleen 3 High
Stomach 3 High
Testis 3 High
Thyroid gland 3 High
Tonsil 3 High
Urinary bladder 3 High
Vagina 3 High
Summary
SymbolLMNB1
Namelamin B1
Aliases ADLD; LMN; LMNB; Lamin-B1
Location5q23.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Association between expresson and subtype
> Overall survival analysis based on expression
> Association between expresson and stage
> Association between expresson and grade
> Subtype
 


  Association between expresson and subtype.
Cancer Full Name # Patients P Value (Kruskal-Wallis) Association Source
BLCABladder urothelial carcinoma1280.021Significant24476821
BRCABreast invasive carcinoma5217.91e-46Significant23000897
COADColon adenocarcinoma1490.000233Significant22810696
GBMGlioblastoma multiforme1572.87e-06Significant26824661
HNSCHead and Neck squamous cell carcinoma2791.23e-07Significant25631445
KIRPKidney renal papillary cell carcinoma1610.0407Significant26536169
LGGBrain Lower Grade Glioma5130.000295Significant26824661
LUADLung adenocarcinoma2306.45e-13Significant25079552
LUSCLung squamous cell carcinoma1789.04e-05Significant22960745
OVOvarian serous cystadenocarcinoma2874e-04Significant21720365
PRADProstate adenocarcinoma3330.0187Significant26544944
READRectum adenocarcinoma670.12NS22810696
SKCMSkin Cutaneous Melanoma3150.608NS26091043
STADStomach adenocarcinoma2773.43e-16Significant25079317
THCAThyroid carcinoma3915.47e-09Significant25417114
UCECUterine Corpus Endometrial Carcinoma2329.52e-09Significant23636398
> Overall survival
 

  Overall survival analysis based on expression.
Cancer Full Name # Patients Hazard Ratio P Value (Log Rank Test) Association
BLCABladder urothelial carcinoma405 1.0040.984NS
BRCABreast invasive carcinoma1079 1.2790.277NS
CESCCervical and endocervical cancers291 0.5310.0548NS
COADColon adenocarcinoma439 0.8140.478NS
ESCAEsophageal carcinoma184 1.4810.239NS
GBMGlioblastoma multiforme158 1.1280.643NS
HNSCHead and Neck squamous cell carcinoma518 0.9910.966NS
KIRCKidney renal clear cell carcinoma531 2.10.000319Shorter
KIRPKidney renal papillary cell carcinoma287 5.3174.79e-05Shorter
LAMLAcute Myeloid Leukemia149 0.5010.0182Longer
LGGBrain Lower Grade Glioma511 2.668.31e-05Shorter
LIHCLiver hepatocellular carcinoma365 2.5740.000171Shorter
LUADLung adenocarcinoma502 2.130.000569Shorter
LUSCLung squamous cell carcinoma494 0.6950.0564NS
OVOvarian serous cystadenocarcinoma303 1.1460.515NS
PAADPancreatic adenocarcinoma177 2.2440.00702Shorter
PCPGPheochromocytoma and Paraganglioma179 4.1130.172NS
PRADProstate adenocarcinoma497 1.8290.479NS
READRectum adenocarcinoma159 0.3950.165NS
SARCSarcoma259 2.4650.00315Shorter
SKCMSkin Cutaneous Melanoma459 0.9890.953NS
STADStomach adenocarcinoma388 0.530.0062Longer
TGCTTesticular Germ Cell Tumors134 594299979.8380.317NS
THCAThyroid carcinoma500 0.8880.851NS
THYMThymoma119 00.0206Longer
UCECUterine Corpus Endometrial Carcinoma543 1.3030.401NS
> Stage
 

  Association between expresson and stage.
Cancer Full Name # Patients R Value (Spearman) P Value (Spearman) Association
BLCABladder urothelial carcinoma406 0.0010.985NS
BRCABreast invasive carcinoma1071 0.0480.119NS
CESCCervical and endocervical cancers167 0.1490.0552NS
COADColon adenocarcinoma445 -0.1460.002Lower
ESCAEsophageal carcinoma162 0.1010.2NS
HNSCHead and Neck squamous cell carcinoma448 -0.040.401NS
KIRCKidney renal clear cell carcinoma531 0.3048.7e-13Higher
KIRPKidney renal papillary cell carcinoma260 0.4351.86e-13Higher
LIHCLiver hepatocellular carcinoma347 0.1420.00791Higher
LUADLung adenocarcinoma507 0.1460.00102Higher
LUSCLung squamous cell carcinoma497 0.0470.297NS
OVOvarian serous cystadenocarcinoma302 -0.0950.0978NS
PAADPancreatic adenocarcinoma176 0.0990.193NS
READRectum adenocarcinoma156 -0.050.539NS
SKCMSkin Cutaneous Melanoma410 -0.1360.00583Lower
STADStomach adenocarcinoma392 -0.0750.137NS
TGCTTesticular Germ Cell Tumors81 0.4738.12e-06Higher
THCAThyroid carcinoma499 -0.0030.939NS
UCECUterine Corpus Endometrial Carcinoma501 0.1220.00605Higher
> Grade
 

  Association between expresson and grade.
Cancer Full Name # Patients R Value (Spearman) P Value (Spearman) Association
CESCCervical and endocervical cancers272 -0.0010.982NS
HNSCHead and Neck squamous cell carcinoma498 0.2642.07e-09Higher
KIRCKidney renal clear cell carcinoma525 0.3031.3e-12Higher
LGGBrain Lower Grade Glioma514 0.3576.91e-17Higher
LIHCLiver hepatocellular carcinoma366 0.3271.46e-10Higher
OVOvarian serous cystadenocarcinoma296 0.1380.0174Higher
PAADPancreatic adenocarcinoma176 0.1490.0482Higher
STADStomach adenocarcinoma406 0.0420.395NS
UCECUterine Corpus Endometrial Carcinoma534 0.3371.19e-15Higher
Summary
SymbolLMNB1
Namelamin B1
Aliases ADLD; LMN; LMNB; Lamin-B1
Location5q23.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Targets inferred by reverse engineering method
> Targets identified by ChIP-seq data
> Targets inferred by reverse engineering method
 
> Targets identified by ChIP-seq data
 
Summary
SymbolLMNB1
Namelamin B1
Aliases ADLD; LMN; LMNB; Lamin-B1
Location5q23.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Drugs from DrugBank database
> Drugs from DrugBank database
 
There is no record for LMNB1.
Summary
SymbolLMNB1
Namelamin B1
Aliases ADLD; LMN; LMNB; Lamin-B1
Location5q23.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Protein-Protein Interaction Network
> miRNA Regulatory Relationship
> Interactions from Text Mining
> Protein-Protein Interaction Network
 
> miRNA Regulatory Relationship
 
> Interactions from Text Mining
 
There is no record for LMNB1.