CR2Cancer

Summary
Symbol	NCOR1
Name	nuclear receptor corepressor 1
Aliases	N-CoR; hCIT529I10; hN-CoR; KIAA1047; MGC104216; PPP1R109; thyroid hormone- and retinoic acid receptor-associ ......
Location	17p12-p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

[ TOP ]

Domain

PF15784 G-protein pathway suppressor 2-interacting domain
PF00249 Myb-like DNA-binding domain

Function

Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6.

Classification

Class	Modification	Substrate	Product	PubMed
Histone modification erase cofactor	Histone acetylation	#	#	14527417

> Gene Ontology [ TOP ]
Biological Process	GO:0000226 microtubule cytoskeleton organization GO:0001933 negative regulation of protein phosphorylation GO:0006090 pyruvate metabolic process GO:0006091 generation of precursor metabolites and energy GO:0006096 glycolytic process GO:0006109 regulation of carbohydrate metabolic process GO:0006110 regulation of glycolytic process GO:0006140 regulation of nucleotide metabolic process GO:0006165 nucleoside diphosphate phosphorylation GO:0006417 regulation of translation GO:0006732 coenzyme metabolic process GO:0006733 oxidoreduction coenzyme metabolic process GO:0006757 ATP generation from ADP GO:0006820 anion transport GO:0006869 lipid transport GO:0007051 spindle organization GO:0007254 JNK cascade GO:0007623 circadian rhythm GO:0009116 nucleoside metabolic process GO:0009118 regulation of nucleoside metabolic process GO:0009119 ribonucleoside metabolic process GO:0009123 nucleoside monophosphate metabolic process GO:0009126 purine nucleoside monophosphate metabolic process GO:0009132 nucleoside diphosphate metabolic process GO:0009135 purine nucleoside diphosphate metabolic process GO:0009141 nucleoside triphosphate metabolic process GO:0009144 purine nucleoside triphosphate metabolic process GO:0009150 purine ribonucleotide metabolic process GO:0009161 ribonucleoside monophosphate metabolic process GO:0009167 purine ribonucleoside monophosphate metabolic process GO:0009179 purine ribonucleoside diphosphate metabolic process GO:0009185 ribonucleoside diphosphate metabolic process GO:0009199 ribonucleoside triphosphate metabolic process GO:0009205 purine ribonucleoside triphosphate metabolic process GO:0009894 regulation of catabolic process GO:0010608 posttranscriptional regulation of gene expression GO:0010876 lipid localization GO:0015711 organic anion transport GO:0015718 monocarboxylic acid transport GO:0015908 fatty acid transport GO:0016052 carbohydrate catabolic process GO:0016441 posttranscriptional gene silencing GO:0016458 gene silencing GO:0017148 negative regulation of translation GO:0019362 pyridine nucleotide metabolic process GO:0031047 gene silencing by RNA GO:0031050 dsRNA fragmentation GO:0031098 stress-activated protein kinase signaling cascade GO:0032368 regulation of lipid transport GO:0032872 regulation of stress-activated MAPK cascade GO:0032873 negative regulation of stress-activated MAPK cascade GO:0034248 regulation of cellular amide metabolic process GO:0034249 negative regulation of cellular amide metabolic process GO:0034250 positive regulation of cellular amide metabolic process GO:0035194 posttranscriptional gene silencing by RNA GO:0035195 gene silencing by miRNA GO:0035196 production of miRNAs involved in gene silencing by miRNA GO:0040029 regulation of gene expression, epigenetic GO:0042278 purine nucleoside metabolic process GO:0042326 negative regulation of phosphorylation GO:0043331 response to dsRNA GO:0043409 negative regulation of MAPK cascade GO:0043467 regulation of generation of precursor metabolites and energy GO:0043470 regulation of carbohydrate catabolic process GO:0044070 regulation of anion transport GO:0044723 single-organism carbohydrate metabolic process GO:0044724 single-organism carbohydrate catabolic process GO:0045727 positive regulation of translation GO:0046031 ADP metabolic process GO:0046034 ATP metabolic process GO:0046128 purine ribonucleoside metabolic process GO:0046328 regulation of JNK cascade GO:0046329 negative regulation of JNK cascade GO:0046496 nicotinamide nucleotide metabolic process GO:0046939 nucleotide phosphorylation GO:0046942 carboxylic acid transport GO:0048511 rhythmic process GO:0051186 cofactor metabolic process GO:0051193 regulation of cofactor metabolic process GO:0051196 regulation of coenzyme metabolic process GO:0051225 spindle assembly GO:0051403 stress-activated MAPK cascade GO:0060147 regulation of posttranscriptional gene silencing GO:0060149 negative regulation of posttranscriptional gene silencing GO:0060964 regulation of gene silencing by miRNA GO:0060965 negative regulation of gene silencing by miRNA GO:0060966 regulation of gene silencing by RNA GO:0060967 negative regulation of gene silencing by RNA GO:0060968 regulation of gene silencing GO:0060969 negative regulation of gene silencing GO:0070302 regulation of stress-activated protein kinase signaling cascade GO:0070303 negative regulation of stress-activated protein kinase signaling cascade GO:0070918 production of small RNA involved in gene silencing by RNA GO:0070920 regulation of production of small RNA involved in gene silencing by RNA GO:0071359 cellular response to dsRNA GO:0071407 cellular response to organic cyclic compound GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter GO:0072524 pyridine-containing compound metabolic process GO:1900542 regulation of purine nucleotide metabolic process GO:1901657 glycosyl compound metabolic process GO:1902532 negative regulation of intracellular signal transduction GO:1903578 regulation of ATP metabolic process GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA GO:2000191 regulation of fatty acid transport
Molecular Function	GO:0001085 RNA polymerase II transcription factor binding GO:0001102 RNA polymerase II activating transcription factor binding GO:0003714 transcription corepressor activity GO:0008134 transcription factor binding GO:0016922 ligand-dependent nuclear receptor binding GO:0033613 activating transcription factor binding GO:0035257 nuclear hormone receptor binding GO:0042826 histone deacetylase binding GO:0046966 thyroid hormone receptor binding GO:0051427 hormone receptor binding
Cellular Component	GO:0000118 histone deacetylase complex GO:0000785 chromatin GO:0000790 nuclear chromatin GO:0005819 spindle GO:0005874 microtubule GO:0005876 spindle microtubule GO:0016580 Sin3 complex GO:0017053 transcriptional repressor complex GO:0044454 nuclear chromosome part GO:0070822 Sin3-type complex

> KEGG and Reactome Pathway [ TOP ]
KEGG	hsa04919 Thyroid hormone signaling pathway
Reactome	R-HSA-5619507: Activation of HOX genes during differentiation R-HSA-5617472: Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-1368108: BMAL1 R-HSA-3247509: Chromatin modifying enzymes R-HSA-4839726: Chromatin organization R-HSA-400253: Circadian Clock R-HSA-2894862: Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2644606: Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-1266738: Developmental Biology R-HSA-1643685: Disease R-HSA-5663202: Diseases of signal transduction R-HSA-2173795: Downregulation of SMAD2/3 R-HSA-535734: Fatty acid, triacylglycerol, and ketone body metabolism R-HSA-74160: Gene Expression R-HSA-212436: Generic Transcription Pathway R-HSA-3214815: HDACs deacetylate histones R-HSA-1430728: Metabolism R-HSA-556833: Metabolism of lipids and lipoproteins R-HSA-1592230: Mitochondrial biogenesis R-HSA-2122947: NOTCH1 Intracellular Domain Regulates Transcription R-HSA-1368071: NR1D1 (REV-ERBA) represses gene expression R-HSA-1251985: Nuclear signaling by ERBB4 R-HSA-1852241: Organelle biogenesis and maintenance R-HSA-1989781: PPARA activates gene expression R-HSA-1368082: RORA activates gene expression R-HSA-400206: Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) R-HSA-162582: Signal Transduction R-HSA-1236394: Signaling by ERBB4 R-HSA-157118: Signaling by NOTCH R-HSA-1980143: Signaling by NOTCH1 R-HSA-2894858: Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2644602: Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644603: Signaling by NOTCH1 in Cancer R-HSA-170834: Signaling by TGF-beta Receptor Complex R-HSA-2151201: Transcriptional activation of mitochondrial biogenesis R-HSA-2173793: Transcriptional activity of SMAD2/SMAD3 R-HSA-381340: Transcriptional regulation of white adipocyte differentiation

> KEGG and Reactome Pathway

[ TOP ]

KEGG

hsa04919 Thyroid hormone signaling pathway

Reactome

R-HSA-5619507: Activation of HOX genes during differentiation
R-HSA-5617472: Activation of anterior HOX genes in hindbrain development during early embryogenesis
R-HSA-1368108: BMAL1
R-HSA-3247509: Chromatin modifying enzymes
R-HSA-4839726: Chromatin organization
R-HSA-400253: Circadian Clock
R-HSA-2894862: Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
R-HSA-2644606: Constitutive Signaling by NOTCH1 PEST Domain Mutants
R-HSA-1266738: Developmental Biology
R-HSA-1643685: Disease
R-HSA-5663202: Diseases of signal transduction
R-HSA-2173795: Downregulation of SMAD2/3
R-HSA-535734: Fatty acid, triacylglycerol, and ketone body metabolism
R-HSA-74160: Gene Expression
R-HSA-212436: Generic Transcription Pathway
R-HSA-3214815: HDACs deacetylate histones
R-HSA-1430728: Metabolism
R-HSA-556833: Metabolism of lipids and lipoproteins
R-HSA-1592230: Mitochondrial biogenesis
R-HSA-2122947: NOTCH1 Intracellular Domain Regulates Transcription
R-HSA-1368071: NR1D1 (REV-ERBA) represses gene expression
R-HSA-1251985: Nuclear signaling by ERBB4
R-HSA-1852241: Organelle biogenesis and maintenance
R-HSA-1989781: PPARA activates gene expression
R-HSA-1368082: RORA activates gene expression
R-HSA-400206: Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
R-HSA-162582: Signal Transduction
R-HSA-1236394: Signaling by ERBB4
R-HSA-157118: Signaling by NOTCH
R-HSA-1980143: Signaling by NOTCH1
R-HSA-2894858: Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
R-HSA-2644602: Signaling by NOTCH1 PEST Domain Mutants in Cancer
R-HSA-2644603: Signaling by NOTCH1 in Cancer
R-HSA-170834: Signaling by TGF-beta Receptor Complex
R-HSA-2151201: Transcriptional activation of mitochondrial biogenesis
R-HSA-2173793: Transcriptional activity of SMAD2/SMAD3
R-HSA-381340: Transcriptional regulation of white adipocyte differentiation

Summary
Symbol	NCOR1
Name	nuclear receptor corepressor 1
Aliases	N-CoR; hCIT529I10; hN-CoR; KIAA1047; MGC104216; PPP1R109; thyroid hormone- and retinoic acid receptor-associ ......
Location	17p12-p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM975857	c.6705C>A	p.I2235I	Substitution - coding silent	Endometrium
COSM3889351	c.5726C>T	p.P1909L	Substitution - Missense	Skin
COSM4613907	c.1713delG	p.R572fs*18	Deletion - Frameshift	Large_intestine
COSM4767657	c.3275G>A	p.R1092Q	Substitution - Missense	Biliary_tract
COSM5479269	c.5841G>A	p.A1947A	Substitution - coding silent	Large_intestine
COSM2739001	c.4331T>C	p.V1444A	Substitution - Missense	Large_intestine
COSM4623483	c.3337C>T	p.R1113*	Substitution - Nonsense	Large_intestine
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM4064153	c.4667C>T	p.A1556V	Substitution - Missense	Stomach
COSM1686251	c.467C>T	p.P156L	Substitution - Missense	Skin
COSM3514557	c.5000C>T	p.P1667L	Substitution - Missense	Skin
COSM3514556	c.5198C>T	p.S1733F	Substitution - Missense	Skin
COSM254836	c.3016+1G>T	p.?	Unknown	Urinary_tract
COSM87916	c.1584_1585insA	p.E529fs*7	Insertion - Frameshift	Central_nervous_system
COSM5752676	c.3283G>T	p.E1095*	Substitution - Nonsense	Breast
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM254838	c.3184C>T	p.P1062S	Substitution - Missense	Urinary_tract
COSM3514550	c.6941C>T	p.P2314L	Substitution - Missense	Skin
COSM5724266	c.55C>T	p.R19C	Substitution - Missense	Skin
COSM5722574	c.3450C>T	p.T1150T	Substitution - coding silent	Skin
COSM3818894	c.1083-1G>A	p.?	Unknown	Breast
COSM5752612	c.6121C>T	p.Q2041*	Substitution - Nonsense	Breast
COSM1609873	c.6502T>C	p.L2168L	Substitution - coding silent	Liver
COSM1302426	c.1552G>T	p.E518*	Substitution - Nonsense	Urinary_tract
COSM3983274	c.3278A>C	p.Q1093P	Substitution - Missense	Ovary
COSM1709973	c.4694C>T	p.P1565L	Substitution - Missense	Skin
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Thyroid
COSM5725085	c.5065C>T	p.P1689S	Substitution - Missense	Skin
COSM5706307	c.916A>T	p.K306*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM254835	c.4465C>G	p.Q1489E	Substitution - Missense	Urinary_tract
COSM1479263	c.6780T>A	p.N2260K	Substitution - Missense	Breast
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM5648594	c.829G>C	p.E277Q	Substitution - Missense	Oesophagus
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM975864	c.5329G>T	p.G1777*	Substitution - Nonsense	Endometrium
COSM4064171	c.1238G>A	p.R413K	Substitution - Missense	Stomach
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM87916	c.1584_1585insA	p.E529fs*7	Insertion - Frameshift	Breast
COSM975887	c.8G>C	p.S3T	Substitution - Missense	Endometrium
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM5612418	c.4423A>T	p.I1475F	Substitution - Missense	Adrenal_gland
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5419604	c.7268A>G	p.E2423G	Substitution - Missense	Liver
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Central_nervous_system
COSM1195618	c.3821G>A	p.C1274Y	Substitution - Missense	Lung
COSM704908	c.4915G>T	p.E1639*	Substitution - Nonsense	Lung
COSM2738967	c.5497delC	p.Q1833fs*17	Deletion - Frameshift	Large_intestine
COSM1740408	c.5153G>A	p.R1718Q	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3514561	c.3055C>T	p.P1019S	Substitution - Missense	Skin
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Central_nervous_system
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM5752545	c.4084C>T	p.Q1362*	Substitution - Nonsense	Breast
COSM3969842	c.3522G>A	p.Q1174Q	Substitution - coding silent	Central_nervous_system
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Skin
COSM4601098	c.4442C>A	p.A1481E	Substitution - Missense	Upper_aerodigestive_tract
COSM1609877	c.1714C>T	p.R572*	Substitution - Nonsense	Stomach
COSM1684491	c.1763delC	p.M589fs*1	Deletion - Frameshift	Lung
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Upper_aerodigestive_tract
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Central_nervous_system
COSM289297	c.2317A>T	p.K773*	Substitution - Nonsense	Large_intestine
COSM4487973	c.3205C>T	p.H1069Y	Substitution - Missense	Skin
COSM4064154	c.4593G>A	p.A1531A	Substitution - coding silent	Stomach
COSM4502446	c.6139C>T	p.R2047W	Substitution - Missense	Skin
COSM4887518	c.6412G>A	p.E2138K	Substitution - Missense	Upper_aerodigestive_tract
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM5972056	c.4610G>C	p.G1537A	Substitution - Missense	Upper_aerodigestive_tract
COSM4444571	c.1675G>T	p.E559*	Substitution - Nonsense	Large_intestine
COSM4800407	c.313G>A	p.E105K	Substitution - Missense	Liver
COSM5624347	c.1879C>G	p.R627G	Substitution - Missense	Oesophagus
COSM283146	c.4746G>A	p.A1582A	Substitution - coding silent	Large_intestine
COSM1128820	c.2873C>T	p.A958V	Substitution - Missense	Prostate
COSM4644035	c.4124G>A	p.R1375Q	Substitution - Missense	Large_intestine
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Upper_aerodigestive_tract
COSM5752636	c.2659G>T	p.E887*	Substitution - Nonsense	Breast
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5422232	c.676C>T	p.P226S	Substitution - Missense	Prostate
COSM4064147	c.5483C>T	p.A1828V	Substitution - Missense	Stomach
COSM975860	c.6467C>T	p.P2156L	Substitution - Missense	Endometrium
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM4605817	c.7006A>C	p.K2336Q	Substitution - Missense	Upper_aerodigestive_tract
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM1709974	c.3646A>T	p.S1216C	Substitution - Missense	Skin
COSM3765997	c.4153-5T>A	p.?	Unknown	Skin
COSM4064157	c.4469A>G	p.N1490S	Substitution - Missense	Stomach
COSM245971	c.114C>T	p.F38F	Substitution - coding silent	Skin
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM3361997	c.4113C>T	p.V1371V	Substitution - coding silent	Kidney
COSM975878	c.3657C>T	p.I1219I	Substitution - coding silent	Endometrium
COSM254840	c.197G>A	p.R66Q	Substitution - Missense	Large_intestine
COSM225744	c.5263C>T	p.R1755C	Substitution - Missense	Skin
COSM3514565	c.1082+2T>G	p.?	Unknown	Skin
COSM5722574	c.3450C>T	p.T1150T	Substitution - coding silent	Skin
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM4827988	c.2173G>C	p.D725H	Substitution - Missense	Cervix
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Upper_aerodigestive_tract
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Central_nervous_system
COSM254840	c.197G>A	p.R66Q	Substitution - Missense	Urinary_tract
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Central_nervous_system
COSM5706303	c.5620G>T	p.E1874*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM5417167	c.2669A>T	p.D890V	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM704906	c.3242C>T	p.P1081L	Substitution - Missense	Lung
COSM4129611	c.447C>T	p.F149F	Substitution - coding silent	Large_intestine
COSM255406	c.4996C>T	p.H1666Y	Substitution - Missense	Central_nervous_system
COSM975886	c.34G>A	p.A12T	Substitution - Missense	Endometrium
COSM3370625	c.2865C>T	p.S955S	Substitution - coding silent	Thyroid
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Central_nervous_system
COSM975865	c.5264G>A	p.R1755H	Substitution - Missense	Endometrium
COSM3514569	c.436G>A	p.D146N	Substitution - Missense	Skin
COSM5028229	c.7055C>G	p.S2352*	Substitution - Nonsense	Breast
COSM254835	c.4465C>G	p.Q1489E	Substitution - Missense	Urinary_tract
COSM1479274	c.1591G>C	p.E531Q	Substitution - Missense	Breast
COSM4436598	c.3729A>C	p.L1243F	Substitution - Missense	Oesophagus
COSM1216867	c.2866G>A	p.G956S	Substitution - Missense	Large_intestine
COSM1381123	c.5366C>A	p.P1789Q	Substitution - Missense	Large_intestine
COSM3988789	c.4518A>C	p.T1506T	Substitution - coding silent	Kidney
COSM5663682	c.2818A>G	p.M940V	Substitution - Missense	Soft_tissue
COSM3514558	c.4072G>C	p.D1358H	Substitution - Missense	Skin
COSM1216869	c.4373T>C	p.V1458A	Substitution - Missense	Large_intestine
COSM1302425	c.3068G>C	p.R1023P	Substitution - Missense	Urinary_tract
COSM1679604	c.1911A>C	p.K637N	Substitution - Missense	Large_intestine
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM1479270	c.3016+2T>C	p.?	Unknown	Breast
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM436096	c.1774G>T	p.E592*	Substitution - Nonsense	Breast
COSM436091	c.3192_3193insGCCT	p.Y1065fs*7	Insertion - Frameshift	Breast
COSM1609875	c.5549A>C	p.E1850A	Substitution - Missense	Liver
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM5906057	c.1367C>T	p.P456L	Substitution - Missense	Skin
COSM5223824	c.5882-2delA	p.?	Unknown	Breast
COSM5642369	c.2589T>A	p.A863A	Substitution - coding silent	Oesophagus
COSM1381134	c.2273A>G	p.E758G	Substitution - Missense	Large_intestine
COSM1479269	c.3137C>A	p.S1046*	Substitution - Nonsense	Breast
COSM220035	c.3043A>C	p.I1015L	Substitution - Missense	Prostate
COSM124694	c.3113C>G	p.P1038R	Substitution - Missense	Upper_aerodigestive_tract
COSM225744	c.5263C>T	p.R1755C	Substitution - Missense	Skin
COSM4982613	c.1218G>A	p.M406I	Substitution - Missense	Oesophagus
COSM2738952	c.5910C>T	p.S1970S	Substitution - coding silent	Large_intestine
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Upper_aerodigestive_tract
COSM436084	c.6688C>T	p.Q2230*	Substitution - Nonsense	Breast
COSM5725085	c.5065C>T	p.P1689S	Substitution - Missense	Skin
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Upper_aerodigestive_tract
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM1302424	c.6746C>G	p.S2249C	Substitution - Missense	Urinary_tract
COSM5055241	c.5326C>T	p.Q1776*	Substitution - Nonsense	Stomach
COSM975871	c.4444C>T	p.R1482W	Substitution - Missense	Endometrium
COSM4391838	c.5581A>G	p.S1861G	Substitution - Missense	Prostate
COSM5724266	c.55C>T	p.R19C	Substitution - Missense	Skin
COSM6016503	c.2756C>T	p.P919L	Substitution - Missense	Skin
COSM5616896	c.5388-4A>G	p.?	Unknown	Lung
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Central_nervous_system
COSM380128	c.5582G>A	p.S1861N	Substitution - Missense	Lung
COSM1479272	c.2079G>T	p.E693D	Substitution - Missense	Breast
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Upper_aerodigestive_tract
COSM379128	c.2415T>C	p.A805A	Substitution - coding silent	Lung
COSM5752642	c.3499C>T	p.Q1167*	Substitution - Nonsense	Breast
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Thyroid
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM5985976	c.2062C>T	p.R688*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM704898	c.59A>T	p.Y20F	Substitution - Missense	Lung
COSM4765635	c.1585_1586insA	p.E530fs*6	Insertion - Frameshift	Stomach
COSM1381124	c.4629C>T	p.S1543S	Substitution - coding silent	Large_intestine
COSM3773771	c.549G>A	p.Q183Q	Substitution - coding silent	Thyroid
COSM472347	c.2491A>G	p.N831D	Substitution - Missense	Kidney
COSM4486820	c.3054C>T	p.L1018L	Substitution - coding silent	Skin
COSM5752545	c.4084C>T	p.Q1362*	Substitution - Nonsense	Breast
COSM5981146	c.5240G>A	p.R1747Q	Substitution - Missense	Upper_aerodigestive_tract
COSM5752596	c.1603G>T	p.E535*	Substitution - Nonsense	Breast
COSM5986560	c.3016_3016+1ins10	p.V1006fs*15	Unknown	Haematopoietic_and_lymphoid_tissue
COSM6002962	c.3437G>A	p.R1146Q	Substitution - Missense	Prostate
COSM4064156	c.4485C>T	p.G1495G	Substitution - coding silent	Stomach
COSM2739084	c.361C>T	p.R121C	Substitution - Missense	Skin
COSM3983273	c.6169-7T>G	p.?	Unknown	Ovary
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM472343	c.6211C>A	p.Q2071K	Substitution - Missense	Kidney
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Urinary_tract
COSM5574208	c.76C>A	p.Q26K	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4767663	c.512C>T	p.A171V	Substitution - Missense	Biliary_tract
COSM5055239	c.5951C>A	p.P1984Q	Substitution - Missense	Stomach
COSM1679603	c.4876A>C	p.N1626H	Substitution - Missense	Large_intestine
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Upper_aerodigestive_tract
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM975863	c.5453C>T	p.A1818V	Substitution - Missense	Endometrium
COSM5634513	c.1924G>C	p.E642Q	Substitution - Missense	Oesophagus
COSM1493872	c.356T>A	p.F119Y	Substitution - Missense	Kidney
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM1479271	c.2170G>T	p.E724*	Substitution - Nonsense	Breast
COSM1709975	c.3349T>A	p.S1117T	Substitution - Missense	Skin
COSM3742094	c.4393G>T	p.E1465*	Substitution - Nonsense	Liver
COSM254836	c.3016+1G>T	p.?	Unknown	Urinary_tract
COSM1630065	c.4513G>A	p.V1505I	Substitution - Missense	Liver
COSM975870	c.4556C>T	p.S1519L	Substitution - Missense	Endometrium
COSM4151478	c.1727A>G	p.N576S	Substitution - Missense	Kidney
COSM3378086	c.2249C>T	p.A750V	Substitution - Missense	Pancreas
COSM368297	c.2622G>T	p.Q874H	Substitution - Missense	Lung
COSM1679603	c.4876A>C	p.N1626H	Substitution - Missense	Large_intestine
COSM4064161	c.3031C>T	p.P1011S	Substitution - Missense	Stomach
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Upper_aerodigestive_tract
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Thyroid
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM975879	c.3099G>A	p.P1033P	Substitution - coding silent	Endometrium
COSM975861	c.6010A>C	p.N2004H	Substitution - Missense	Endometrium
COSM3889353	c.1763C>T	p.S588F	Substitution - Missense	Skin
COSM254841	c.4349C>T	p.S1450L	Substitution - Missense	Urinary_tract
COSM5900351	c.847C>T	p.Q283*	Substitution - Nonsense	Skin
COSM4950811	c.6050A>G	p.Y2017C	Substitution - Missense	Liver
COSM1381141	c.100C>A	p.H34N	Substitution - Missense	Large_intestine
COSM3514563	c.2563C>T	p.P855S	Substitution - Missense	Skin
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Pancreas
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM4064143	c.7192C>T	p.P2398S	Substitution - Missense	Stomach
COSM975879	c.3099G>A	p.P1033P	Substitution - coding silent	Large_intestine
COSM975867	c.4946C>T	p.T1649M	Substitution - Missense	Endometrium
COSM975868	c.4856C>T	p.T1619I	Substitution - Missense	Endometrium
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Upper_aerodigestive_tract
COSM245970	c.7171C>T	p.R2391W	Substitution - Missense	Prostate
COSM5987217	c.1977_1978insA	p.A660fs*4	Insertion - Frameshift	Salivary_gland
COSM5801147	c.1572_1573insA	p.T525fs*11	Insertion - Frameshift	Breast
COSM245972	c.2182+2T>G	p.?	Unknown	Prostate
COSM436095	c.2065A>T	p.K689*	Substitution - Nonsense	Breast
COSM236805	c.386T>G	p.L129*	Substitution - Nonsense	Prostate
COSM338198	c.5110A>G	p.T1704A	Substitution - Missense	Lung
COSM5752676	c.3283G>T	p.E1095*	Substitution - Nonsense	Breast
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM3514560	c.3113C>T	p.P1038L	Substitution - Missense	Skin
COSM4064151	c.4813G>A	p.A1605T	Substitution - Missense	Stomach
COSM135743	c.3688G>A	p.E1230K	Substitution - Missense	Skin
COSM4064173	c.483G>A	p.S161S	Substitution - coding silent	Stomach
COSM5623152	c.1730G>C	p.S577T	Substitution - Missense	Oesophagus
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM1258847	c.1008C>G	p.S336R	Substitution - Missense	Stomach
COSM5929752	c.6943T>A	p.S2315T	Substitution - Missense	Skin
COSM5801562	c.1583_1584insA	p.E529fs*7	Insertion - Frameshift	Breast
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1679602	c.5096C>T	p.S1699F	Substitution - Missense	Large_intestine
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Thyroid
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM1709976	c.2071C>T	p.R691C	Substitution - Missense	Skin
COSM3672357	c.4573C>T	p.Q1525*	Substitution - Nonsense	Prostate
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM1381119	c.6678G>T	p.M2226I	Substitution - Missense	Large_intestine
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Upper_aerodigestive_tract
COSM4960634	c.2549G>A	p.S850N	Substitution - Missense	Liver
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM245971	c.114C>T	p.F38F	Substitution - coding silent	Prostate
COSM225744	c.5263C>T	p.R1755C	Substitution - Missense	Breast
COSM1609877	c.1714C>T	p.R572*	Substitution - Nonsense	Liver
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Thyroid
COSM5880293	c.3222C>A	p.Y1074*	Substitution - Nonsense	Skin
COSM704899	c.436G>T	p.D146Y	Substitution - Missense	Lung
COSM5921198	c.1904T>C	p.V635A	Substitution - Missense	Skin
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM2739032	c.2357A>G	p.D786G	Substitution - Missense	Large_intestine
COSM3818887	c.5450C>A	p.A1817D	Substitution - Missense	Breast
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM4497842	c.5021C>T	p.P1674L	Substitution - Missense	Skin
COSM5688754	c.4051A>T	p.I1351F	Substitution - Missense	Soft_tissue
COSM5547305	c.3732_3758del27	p.K1244_G1252delKRSYESVEG	Deletion - In frame	Prostate
COSM975885	c.196C>A	p.R66R	Substitution - coding silent	Endometrium
COSM3770115	c.3839G>A	p.G1280E	Substitution - Missense	Soft_tissue
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM436099	c.514delT	p.S172fs*10	Deletion - Frameshift	Breast
COSM4064159	c.4125G>A	p.R1375R	Substitution - coding silent	Stomach
COSM4064168	c.1751G>A	p.R584Q	Substitution - Missense	Stomach
COSM4129610	c.528C>T	p.L176L	Substitution - coding silent	Thyroid
COSM4492881	c.4009C>T	p.P1337S	Substitution - Missense	Skin
COSM5030993	c.3647G>A	p.S1216N	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Thyroid
COSM2738961	c.5764A>C	p.R1922R	Substitution - coding silent	Upper_aerodigestive_tract
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Pancreas
COSM3818889	c.5380C>T	p.R1794*	Substitution - Nonsense	Breast
COSM3818888	c.5449G>A	p.A1817T	Substitution - Missense	Breast
COSM4936304	c.4491C>A	p.P1497P	Substitution - coding silent	Liver
COSM436083	c.7010C>T	p.S2337F	Substitution - Missense	Breast
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM5614434	c.5590C>T	p.Q1864*	Substitution - Nonsense	Lung
COSM1741040	c.5153_5164del12	p.R1718_K1722>Q	Complex - deletion inframe	Haematopoietic_and_lymphoid_tissue
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM5958085	c.1755C>T	p.I585I	Substitution - coding silent	Thyroid
COSM3742095	c.4353G>T	p.V1451V	Substitution - coding silent	Liver
COSM5574206	c.2224A>G	p.T742A	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM126825	c.2125C>T	p.Q709*	Substitution - Nonsense	Biliary_tract
COSM975881	c.2793G>A	p.Q931Q	Substitution - coding silent	Endometrium
COSM4064172	c.1082+2T>C	p.?	Unknown	Stomach
COSM3514567	c.641C>T	p.A214V	Substitution - Missense	Skin
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Urinary_tract
COSM254836	c.3016+1G>T	p.?	Unknown	Urinary_tract
COSM262336	c.3338G>A	p.R1113Q	Substitution - Missense	Large_intestine
COSM417180	c.1879C>T	p.R627*	Substitution - Nonsense	Urinary_tract
COSM1479265	c.5374C>T	p.Q1792*	Substitution - Nonsense	Breast
COSM3795297	c.6813C>T	p.L2271L	Substitution - coding silent	Urinary_tract
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Upper_aerodigestive_tract
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM1381135	c.2271G>A	p.T757T	Substitution - coding silent	Large_intestine
COSM3983274	c.3278A>C	p.Q1093P	Substitution - Missense	Ovary
COSM1609873	c.6502T>C	p.L2168L	Substitution - coding silent	Liver
COSM4767657	c.3275G>A	p.R1092Q	Substitution - Missense	Biliary_tract
COSM1290639	c.2182+1G>A	p.?	Unknown	Haematopoietic_and_lymphoid_tissue
COSM3988790	c.161C>G	p.S54*	Substitution - Nonsense	Kidney
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Upper_aerodigestive_tract
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM704900	c.459T>C	p.H153H	Substitution - coding silent	Lung
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM4579466	c.4320A>G	p.A1440A	Substitution - coding silent	Bone
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM4410080	c.2638A>G	p.S880G	Substitution - Missense	Oesophagus
COSM5574204	c.6038C>T	p.P2013L	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM2738958	c.5818_5830del13	p.Q1940fs*32	Deletion - Frameshift	Large_intestine
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Large_intestine
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM1609877	c.1714C>T	p.R572*	Substitution - Nonsense	Liver
COSM4129611	c.447C>T	p.F149F	Substitution - coding silent	Thyroid
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Thyroid
COSM126825	c.2125C>T	p.Q709*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM5752181	c.1879delC	p.R627fs*14	Deletion - Frameshift	Breast
COSM975871	c.4444C>T	p.R1482W	Substitution - Missense	Stomach
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Large_intestine
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM4064149	c.5159G>A	p.R1720Q	Substitution - Missense	Stomach
COSM417181	c.2720T>C	p.L907P	Substitution - Missense	Urinary_tract
COSM254835	c.4465C>G	p.Q1489E	Substitution - Missense	Urinary_tract
COSM3765996	c.4218A>C	p.L1406F	Substitution - Missense	Liver
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Skin
COSM3765997	c.4153-5T>A	p.?	Unknown	Liver
COSM1679604	c.1911A>C	p.K637N	Substitution - Missense	Large_intestine
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM5833225	c.4852delA	p.I1618fs*8	Deletion - Frameshift	Breast
COSM975859	c.6499C>A	p.L2167I	Substitution - Missense	Endometrium
COSM5005033	c.560G>A	p.R187H	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4497842	c.5021C>T	p.P1674L	Substitution - Missense	Skin
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Upper_aerodigestive_tract
COSM3514569	c.436G>A	p.D146N	Substitution - Missense	Skin
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM704907	c.3564G>T	p.S1188S	Substitution - coding silent	Lung
COSM2739045	c.1493G>A	p.R498H	Substitution - Missense	Large_intestine
COSM3514571	c.65C>T	p.P22L	Substitution - Missense	Skin
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Upper_aerodigestive_tract
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Upper_aerodigestive_tract
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Urinary_tract
COSM975883	c.887G>T	p.R296I	Substitution - Missense	Endometrium
COSM3722726	c.450A>G	p.G150G	Substitution - coding silent	Upper_aerodigestive_tract
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Central_nervous_system
COSM3773771	c.549G>A	p.Q183Q	Substitution - coding silent	Large_intestine
COSM1609874	c.5541_5565del25	p.R1848fs*11	Deletion - Frameshift	Liver
COSM5921196	c.2728C>T	p.P910S	Substitution - Missense	Skin
COSM2738986	c.5086G>C	p.A1696P	Substitution - Missense	Upper_aerodigestive_tract
COSM4541346	c.298G>A	p.D100N	Substitution - Missense	Skin
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM4064169	c.1401G>A	p.E467E	Substitution - coding silent	Stomach
COSM975869	c.4600C>T	p.P1534S	Substitution - Missense	Endometrium
COSM704905	c.2602G>T	p.A868S	Substitution - Missense	Lung
COSM5206185	c.4951+2T>C	p.?	Unknown	Haematopoietic_and_lymphoid_tissue
COSM3818897	c.277C>T	p.H93Y	Substitution - Missense	Breast
COSM3421308	c.2107G>A	p.A703T	Substitution - Missense	Large_intestine
COSM5712775	c.2931G>T	p.R977R	Substitution - coding silent	Central_nervous_system
COSM3765997	c.4153-5T>A	p.?	Unknown	Liver
COSM2739032	c.2357A>G	p.D786G	Substitution - Missense	Large_intestine
COSM3514564	c.1706C>T	p.P569L	Substitution - Missense	Skin
COSM3818891	c.3325G>A	p.E1109K	Substitution - Missense	Breast
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM1381120	c.6446C>A	p.P2149H	Substitution - Missense	Large_intestine
COSM5752306	c.1576_1577delGA	p.E526fs*9	Deletion - Frameshift	Breast
COSM4064166	c.1773C>T	p.N591N	Substitution - coding silent	Stomach
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Upper_aerodigestive_tract
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM5724266	c.55C>T	p.R19C	Substitution - Missense	Skin
COSM162844	c.6332A>T	p.H2111L	Substitution - Missense	Breast
COSM4485412	c.292C>T	p.P98S	Substitution - Missense	Skin
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Thyroid
COSM1630064	c.6029A>G	p.Y2010C	Substitution - Missense	Liver
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM5972058	c.2080C>A	p.R694R	Substitution - coding silent	Upper_aerodigestive_tract
COSM4634158	c.3834C>A	p.P1278P	Substitution - coding silent	Large_intestine
COSM4778513	c.898A>T	p.R300*	Substitution - Nonsense	Liver
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM341088	c.1839G>A	p.P613P	Substitution - coding silent	Large_intestine
COSM5667487	c.732+2T>A	p.?	Unknown	Soft_tissue
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Kidney
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Central_nervous_system
COSM5364079	c.6299G>A	p.R2100H	Substitution - Missense	Large_intestine
COSM3765997	c.4153-5T>A	p.?	Unknown	Skin
COSM1381122	c.6122A>G	p.Q2041R	Substitution - Missense	Large_intestine
COSM71798	c.2899A>G	p.M967V	Substitution - Missense	Ovary
COSM4405697	c.6323A>G	p.Q2108R	Substitution - Missense	Skin
COSM1609876	c.5541delC	p.R1848fs*2	Deletion - Frameshift	Liver
COSM4064158	c.4454C>A	p.P1485H	Substitution - Missense	Stomach
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM975858	c.6633G>T	p.E2211D	Substitution - Missense	Endometrium
COSM5574211	c.6322C>T	p.Q2108*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM5363864	c.3001_3004delAACA	p.N1001fs*13	Deletion - Frameshift	Large_intestine
COSM2739005	c.4081A>T	p.T1361S	Substitution - Missense	Large_intestine
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM4064150	c.5101+2T>C	p.?	Unknown	Stomach
COSM5752327	c.1791_1837del47	p.A599fs*23	Deletion - Frameshift	Breast
COSM5765284	c.2940A>T	p.Q980H	Substitution - Missense	Large_intestine
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM3514555	c.5460C>T	p.A1820A	Substitution - coding silent	Skin
COSM3818896	c.358C>T	p.Q120*	Substitution - Nonsense	Breast
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Pancreas
COSM4605707	c.6319G>T	p.A2107S	Substitution - Missense	Upper_aerodigestive_tract
COSM1679602	c.5096C>T	p.S1699F	Substitution - Missense	Large_intestine
COSM2739029	c.2465_2466delTG	p.V822fs*3	Deletion - Frameshift	Large_intestine
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Large_intestine
COSM1709972	c.6433G>A	p.E2145K	Substitution - Missense	Skin
COSM5777782	c.6295A>C	p.N2099H	Substitution - Missense	Breast
COSM1236090	c.1066C>G	p.Q356E	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5456585	c.1738C>T	p.R580C	Substitution - Missense	Large_intestine
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM273000	c.5033T>A	p.I1678N	Substitution - Missense	Large_intestine
COSM1381127	c.3440G>A	p.G1147E	Substitution - Missense	Liver
COSM3514561	c.3055C>T	p.P1019S	Substitution - Missense	Skin
COSM4138125	c.2518A>C	p.N840H	Substitution - Missense	Pancreas
COSM1719633	c.3485_3486GG>AA	p.R1162Q	Substitution - Missense	Skin
COSM5487582	c.3082C>T	p.R1028*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM162847	c.1135G>T	p.E379*	Substitution - Nonsense	Breast
COSM2150780	c.5152C>T	p.R1718W	Substitution - Missense	Central_nervous_system
COSM5985978	c.1353-1G>T	p.?	Unknown	Haematopoietic_and_lymphoid_tissue
COSM340462	c.494G>T	p.C165F	Substitution - Missense	Lung
COSM386778	c.4309G>T	p.D1437Y	Substitution - Missense	Lung
COSM975862	c.5509T>C	p.S1837P	Substitution - Missense	Endometrium
COSM4640088	c.1461T>C	p.Y487Y	Substitution - coding silent	Large_intestine
COSM5725085	c.5065C>T	p.P1689S	Substitution - Missense	Skin
COSM3387722	c.98G>T	p.R33L	Substitution - Missense	Pancreas
COSM4642076	c.1960G>A	p.V654M	Substitution - Missense	Large_intestine
COSM124696	c.424G>C	p.D142H	Substitution - Missense	Upper_aerodigestive_tract
COSM2739021	c.2833C>T	p.P945S	Substitution - Missense	Prostate
COSM4960889	c.1095G>A	p.R365R	Substitution - coding silent	Liver
COSM5574213	c.3360G>C	p.E1120D	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Upper_aerodigestive_tract
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Upper_aerodigestive_tract
COSM1479276	c.660G>A	p.E220E	Substitution - coding silent	Breast
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Upper_aerodigestive_tract
COSM3402623	c.658G>A	p.E220K	Substitution - Missense	Breast
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Central_nervous_system
COSM3514553	c.6206C>T	p.S2069F	Substitution - Missense	Skin
COSM254837	c.1446G>C	p.K482N	Substitution - Missense	Urinary_tract
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Upper_aerodigestive_tract
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM5625179	c.334G>T	p.E112*	Substitution - Nonsense	Oesophagus
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Upper_aerodigestive_tract
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Upper_aerodigestive_tract
COSM4064155	c.4561C>T	p.L1521L	Substitution - coding silent	Stomach
COSM4605410	c.4572C>T	p.T1524T	Substitution - coding silent	Upper_aerodigestive_tract
COSM4705984	c.2179G>A	p.E727K	Substitution - Missense	Large_intestine
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM2739044	c.1584delA	p.E529fs*26	Deletion - Frameshift	Breast
COSM975884	c.442G>A	p.A148T	Substitution - Missense	Endometrium
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Skin
COSM4064152	c.4688A>G	p.H1563R	Substitution - Missense	Stomach
COSM5385751	c.6074C>T	p.S2025F	Substitution - Missense	Skin
COSM3988788	c.4798C>A	p.Q1600K	Substitution - Missense	Kidney
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Kidney
COSM3672358	c.1708C>A	p.R570R	Substitution - coding silent	Prostate
COSM1479262	c.7190C>T	p.P2397L	Substitution - Missense	Breast
COSM3514562	c.2846C>T	p.P949L	Substitution - Missense	Skin
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Large_intestine
COSM330331	c.4087G>T	p.E1363*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM2150780	c.5152C>T	p.R1718W	Substitution - Missense	Central_nervous_system
COSM975882	c.2652C>T	p.S884S	Substitution - coding silent	Endometrium
COSM2738952	c.5910C>T	p.S1970S	Substitution - coding silent	Large_intestine
COSM975866	c.5223C>T	p.G1741G	Substitution - coding silent	Endometrium
COSM3787275	c.2016A>G	p.R672R	Substitution - coding silent	Pancreas
COSM5517019	c.5977C>T	p.Q1993*	Substitution - Nonsense	Biliary_tract
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM2738961	c.5764A>C	p.R1922R	Substitution - coding silent	Upper_aerodigestive_tract
COSM1381128	c.3198G>T	p.L1066F	Substitution - Missense	Large_intestine
COSM3818886	c.5533G>A	p.E1845K	Substitution - Missense	Breast
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM4498146	c.5091C>T	p.S1697S	Substitution - coding silent	Skin
COSM1609873	c.6502T>C	p.L2168L	Substitution - coding silent	Liver
COSM3514552	c.6386G>A	p.R2129K	Substitution - Missense	Skin
COSM3818892	c.3086C>A	p.P1029Q	Substitution - Missense	Breast
COSM3773771	c.549G>A	p.Q183Q	Substitution - coding silent	Upper_aerodigestive_tract
COSM975880	c.2797C>T	p.R933*	Substitution - Nonsense	Large_intestine
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM254840	c.197G>A	p.R66Q	Substitution - Missense	Urinary_tract
COSM1630065	c.4513G>A	p.V1505I	Substitution - Missense	Liver
COSM3818893	c.1174-1G>T	p.?	Unknown	Breast
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Liver
COSM4647997	c.7293G>A	p.Q2431Q	Substitution - coding silent	Large_intestine
COSM4745714	c.130C>T	p.R44C	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1479275	c.1573_1574insA	p.T525fs*11	Insertion - Frameshift	Salivary_gland
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM5773971	c.5561G>C	p.R1854T	Substitution - Missense	Breast
COSM1733498	c.3890T>C	p.M1297T	Substitution - Missense	Pancreas
COSM3514570	c.196C>T	p.R66*	Substitution - Nonsense	Large_intestine
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Thyroid
COSM472346	c.3794T>C	p.V1265A	Substitution - Missense	Kidney
COSM126825	c.2125C>T	p.Q709*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM4064174	c.311T>C	p.L104P	Substitution - Missense	Stomach
COSM3691333	c.3935T>C	p.L1312P	Substitution - Missense	Large_intestine
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM1479275	c.1573_1574insA	p.T525fs*11	Insertion - Frameshift	Pleura
COSM5752612	c.6121C>T	p.Q2041*	Substitution - Nonsense	Breast
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM4441156	c.2588C>A	p.A863D	Substitution - Missense	Large_intestine
COSM3514568	c.460G>A	p.E154K	Substitution - Missense	Skin
COSM472345	c.5544G>T	p.R1848S	Substitution - Missense	Kidney
COSM5808893	c.6733G>A	p.G2245S	Substitution - Missense	Liver
COSM1239562	c.699C>T	p.R233R	Substitution - coding silent	Oesophagus
COSM975880	c.2797C>T	p.R933*	Substitution - Nonsense	Large_intestine
COSM5933627	c.4246G>A	p.G1416R	Substitution - Missense	Skin
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM1470900	c.3837G>T	p.R1279S	Substitution - Missense	Prostate
COSM2739019	c.2884C>T	p.R962*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM4497842	c.5021C>T	p.P1674L	Substitution - Missense	Skin
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Thyroid
COSM975877	c.3686G>A	p.R1229Q	Substitution - Missense	Endometrium
COSM4972839	c.2419G>A	p.E807K	Substitution - Missense	Oesophagus
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM5752596	c.1603G>T	p.E535*	Substitution - Nonsense	Breast
COSM1479275	c.1573_1574insA	p.T525fs*11	Insertion - Frameshift	Breast
COSM5929751	c.5728C>T	p.P1910S	Substitution - Missense	Skin
COSM254840	c.197G>A	p.R66Q	Substitution - Missense	Endometrium
COSM3969841	c.4070A>G	p.Q1357R	Substitution - Missense	Central_nervous_system
COSM1381140	c.422C>T	p.A141V	Substitution - Missense	Large_intestine
COSM5747819	c.3460T>C	p.S1154P	Substitution - Missense	Pancreas
COSM5760453	c.1989A>T	p.K663N	Substitution - Missense	Bone
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM5574215	c.6302_6303insA	p.Y2101fs*1	Insertion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM975855	c.7041G>A	p.T2347T	Substitution - coding silent	Endometrium
COSM4548616	c.451G>A	p.G151S	Substitution - Missense	Skin
COSM5986666	c.1124delG	p.S376fs*27	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Urinary_tract
COSM97914	c.4135G>A	p.E1379K	Substitution - Missense	Upper_aerodigestive_tract
COSM5682781	c.97C>G	p.R33G	Substitution - Missense	Soft_tissue
COSM5454510	c.6421C>T	p.H2141Y	Substitution - Missense	Large_intestine
COSM1686251	c.467C>T	p.P156L	Substitution - Missense	Skin
COSM352636	c.6149C>A	p.T2050K	Substitution - Missense	Lung
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Upper_aerodigestive_tract
COSM975872	c.4436C>T	p.T1479I	Substitution - Missense	Endometrium
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM167184	c.5381G>A	p.R1794Q	Substitution - Missense	Endometrium
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Upper_aerodigestive_tract
COSM4064148	c.5393T>A	p.L1798Q	Substitution - Missense	Stomach
COSM3818890	c.4882C>T	p.R1628C	Substitution - Missense	Breast
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM5773263	c.468A>G	p.P156P	Substitution - coding silent	Breast
COSM436092	c.3022C>T	p.Q1008*	Substitution - Nonsense	Breast
COSM2738999	c.4340G>A	p.R1447Q	Substitution - Missense	Skin
COSM1381117	c.7172G>A	p.R2391Q	Substitution - Missense	Large_intestine
COSM4064163	c.2171A>T	p.E724V	Substitution - Missense	Stomach
COSM5724266	c.55C>T	p.R19C	Substitution - Missense	Skin
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM4964756	c.5281G>A	p.V1761I	Substitution - Missense	Pancreas
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Central_nervous_system
COSM4064144	c.6945A>G	p.S2315S	Substitution - coding silent	Stomach
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Kidney
COSM5712779	c.98G>A	p.R33H	Substitution - Missense	Central_nervous_system
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM1479275	c.1573_1574insA	p.T525fs*11	Insertion - Frameshift	Breast
COSM2738964	c.5609C>A	p.T1870N	Substitution - Missense	Upper_aerodigestive_tract
COSM2739021	c.2833C>T	p.P945S	Substitution - Missense	Skin
COSM436100	c.435+2T>C	p.?	Unknown	Stomach
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Upper_aerodigestive_tract
COSM2738961	c.5764A>C	p.R1922R	Substitution - coding silent	Upper_aerodigestive_tract
COSM1381121	c.6278T>C	p.V2093A	Substitution - Missense	Large_intestine
COSM4425734	c.6169-4A>G	p.?	Unknown	Oesophagus
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Upper_aerodigestive_tract
COSM4151477	c.1766T>A	p.M589K	Substitution - Missense	Kidney
COSM975875	c.3930T>C	p.D1310D	Substitution - coding silent	Endometrium
COSM1479264	c.6705C>G	p.I2235M	Substitution - Missense	Breast
COSM5897958	c.3943C>T	p.P1315S	Substitution - Missense	Skin
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Central_nervous_system
COSM5816763	c.4476G>T	p.M1492I	Substitution - Missense	Liver
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM22046	c.5133T>A	p.S1711R	Substitution - Missense	Kidney
COSM3969843	c.1613A>G	p.K538R	Substitution - Missense	Central_nervous_system
COSM5664967	c.155A>T	p.Q52L	Substitution - Missense	Soft_tissue
COSM1726113	c.7187C>G	p.T2396S	Substitution - Missense	Liver
COSM5986664	c.5054_5057delAGAT	p.Q1685fs*76	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM975880	c.2797C>T	p.R933*	Substitution - Nonsense	Endometrium
COSM2738986	c.5086G>C	p.A1696P	Substitution - Missense	Upper_aerodigestive_tract
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM460411	c.3671-1G>A	p.?	Unknown	Cervix
COSM704910	c.4916A>G	p.E1639G	Substitution - Missense	Lung
COSM5722574	c.3450C>T	p.T1150T	Substitution - coding silent	Skin
COSM1686251	c.467C>T	p.P156L	Substitution - Missense	Skin
COSM1479275	c.1573_1574insA	p.T525fs*11	Insertion - Frameshift	Breast
COSM3818895	c.473C>T	p.S158F	Substitution - Missense	Breast
COSM3787275	c.2016A>G	p.R672R	Substitution - coding silent	Pancreas
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Thyroid
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM126825	c.2125C>T	p.Q709*	Substitution - Nonsense	Biliary_tract
COSM382824	c.2332G>A	p.E778K	Substitution - Missense	Lung
COSM1237863	c.5603A>T	p.Q1868L	Substitution - Missense	Thyroid
COSM2738991	c.4830A>G	p.R1610R	Substitution - coding silent	Large_intestine
COSM975856	c.7004C>A	p.S2335Y	Substitution - Missense	Endometrium
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM4064165	c.1806G>A	p.A602A	Substitution - coding silent	Stomach
COSM162849	c.937C>T	p.Q313*	Substitution - Nonsense	Breast
COSM254841	c.4349C>T	p.S1450L	Substitution - Missense	Urinary_tract
COSM4623481	c.6298C>T	p.R2100C	Substitution - Missense	Large_intestine
COSM4800407	c.313G>A	p.E105K	Substitution - Missense	Liver
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3370624	c.4182A>T	p.S1394S	Substitution - coding silent	Thyroid
COSM4449860	c.3497_3500delCTCA	p.T1166fs*17	Deletion - Frameshift	Skin
COSM2739044	c.1584delA	p.E529fs*26	Deletion - Frameshift	Prostate
COSM1756932	c.2080C>T	p.R694*	Substitution - Nonsense	Urinary_tract
COSM4705981	c.3325G>T	p.E1109*	Substitution - Nonsense	Large_intestine
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM4489753	c.3480C>T	p.S1160S	Substitution - coding silent	Skin
COSM975873	c.4036G>T	p.E1346*	Substitution - Nonsense	Endometrium
COSM1381129	c.3098C>T	p.P1033L	Substitution - Missense	Large_intestine
COSM4835560	c.3602G>A	p.R1201K	Substitution - Missense	Cervix
COSM6002964	c.2981G>A	p.C994Y	Substitution - Missense	Prostate
COSM4767659	c.2616G>T	p.E872D	Substitution - Missense	Biliary_tract
COSM3514566	c.865C>T	p.L289F	Substitution - Missense	Skin
COSM5385753	c.2697T>G	p.F899L	Substitution - Missense	Skin
COSM5672127	c.1257C>A	p.N419K	Substitution - Missense	Soft_tissue
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Upper_aerodigestive_tract
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM5985973	c.3685C>T	p.R1229*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM3969840	c.6725C>G	p.T2242S	Substitution - Missense	Central_nervous_system
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Upper_aerodigestive_tract
COSM2739012	c.3405C>T	p.T1135T	Substitution - coding silent	Thyroid
COSM4064162	c.2746G>A	p.V916I	Substitution - Missense	Stomach
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM3818884	c.5725C>T	p.P1909S	Substitution - Missense	Breast
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM4064164	c.1903G>A	p.V635I	Substitution - Missense	Stomach
COSM1381126	c.4195A>G	p.I1399V	Substitution - Missense	Large_intestine
COSM1479275	c.1573_1574insA	p.T525fs*11	Insertion - Frameshift	Breast
COSM460409	c.2034C>T	p.L678L	Substitution - coding silent	Cervix
COSM1381139	c.963delA	p.V322fs*4	Deletion - Frameshift	Large_intestine
COSM4064145	c.6190G>A	p.A2064T	Substitution - Missense	Stomach
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM4605091	c.3102C>T	p.P1034P	Substitution - coding silent	Upper_aerodigestive_tract
COSM2739002	c.4224G>T	p.T1408T	Substitution - coding silent	Liver
COSM436086	c.5521G>C	p.E1841Q	Substitution - Missense	Breast
COSM1756932	c.2080C>T	p.R694*	Substitution - Nonsense	Oesophagus
COSM2739021	c.2833C>T	p.P945S	Substitution - Missense	Large_intestine
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM4579468	c.3504C>T	p.G1168G	Substitution - coding silent	Bone
COSM3378086	c.2249C>T	p.A750V	Substitution - Missense	Pancreas
COSM1719633	c.3485_3486GG>AA	p.R1162Q	Substitution - Missense	Skin
COSM1216870	c.929G>A	p.R310H	Substitution - Missense	Large_intestine
COSM1479268	c.3522G>C	p.Q1174H	Substitution - Missense	Breast
COSM6002473	c.4294C>T	p.R1432W	Substitution - Missense	Prostate
COSM5765264	c.2938C>G	p.Q980E	Substitution - Missense	Large_intestine
COSM262336	c.3338G>A	p.R1113Q	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM349281	c.6279G>A	p.V2093V	Substitution - coding silent	Lung
COSM254839	c.733-1G>C	p.?	Unknown	Urinary_tract
COSM4605118	c.3227A>C	p.Q1076P	Substitution - Missense	Upper_aerodigestive_tract
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Upper_aerodigestive_tract
COSM4950811	c.6050A>G	p.Y2017C	Substitution - Missense	Liver
COSM254837	c.1446G>C	p.K482N	Substitution - Missense	Urinary_tract
COSM5798901	c.7253G>A	p.R2418K	Substitution - Missense	Breast
COSM4993948	c.2014C>T	p.R672*	Substitution - Nonsense	Large_intestine
COSM2738945	c.6397C>T	p.P2133S	Substitution - Missense	Large_intestine
COSM5442103	c.2295C>G	p.P765P	Substitution - coding silent	Oesophagus
COSM5487582	c.3082C>T	p.R1028*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM97921	c.2411G>A	p.S804N	Substitution - Missense	Upper_aerodigestive_tract
COSM379127	c.6390A>G	p.G2130G	Substitution - coding silent	Lung
COSM975854	c.7264C>T	p.R2422*	Substitution - Nonsense	Endometrium
COSM3514554	c.5533G>T	p.E1845*	Substitution - Nonsense	Skin
COSM5462601	c.5272T>C	p.S1758P	Substitution - Missense	Large_intestine
COSM5752181	c.1879delC	p.R627fs*14	Deletion - Frameshift	Breast
COSM3755282	c.6544G>A	p.A2182T	Substitution - Missense	Large_intestine
COSM5815455	c.2821-2A>G	p.?	Unknown	Liver
COSM2739025	c.2665G>A	p.V889M	Substitution - Missense	Large_intestine
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Kidney
COSM704901	c.530C>G	p.S177*	Substitution - Nonsense	Lung
COSM3421307	c.2416G>T	p.E806*	Substitution - Nonsense	Large_intestine
COSM4064146	c.5949G>A	p.A1983A	Substitution - coding silent	Stomach
COSM1684490	c.2463_2464delTG	p.V822fs*3	Deletion - Frameshift	Large_intestine
COSM3514551	c.6640C>T	p.R2214C	Substitution - Missense	Skin
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Central_nervous_system
COSM254840	c.197G>A	p.R66Q	Substitution - Missense	Urinary_tract
COSM2739021	c.2833C>T	p.P945S	Substitution - Missense	Large_intestine
COSM4064167	c.1768A>G	p.T590A	Substitution - Missense	Stomach
COSM472344	c.5798T>C	p.I1933T	Substitution - Missense	Kidney
COSM254837	c.1446G>C	p.K482N	Substitution - Missense	Urinary_tract
COSM162849	c.937C>T	p.Q313*	Substitution - Nonsense	Breast
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM4129610	c.528C>T	p.L176L	Substitution - coding silent	Thyroid
COSM5770802	c.395C>G	p.P132R	Substitution - Missense	Breast
COSM255406	c.4996C>T	p.H1666Y	Substitution - Missense	Central_nervous_system
COSM1520559	c.470C>T	p.S157F	Substitution - Missense	Skin
COSM704911	c.6441C>A	p.Y2147*	Substitution - Nonsense	Lung
COSM975874	c.3932G>A	p.G1311D	Substitution - Missense	Endometrium
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM5981148	c.5225C>T	p.S1742L	Substitution - Missense	Upper_aerodigestive_tract
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Upper_aerodigestive_tract
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM254841	c.4349C>T	p.S1450L	Substitution - Missense	Urinary_tract
COSM2739032	c.2357A>G	p.D786G	Substitution - Missense	Large_intestine
COSM3773771	c.549G>A	p.Q183Q	Substitution - coding silent	Kidney
COSM3889352	c.4375C>T	p.L1459F	Substitution - Missense	Skin
COSM4129610	c.528C>T	p.L176L	Substitution - coding silent	Upper_aerodigestive_tract
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Upper_aerodigestive_tract
COSM3402623	c.658G>A	p.E220K	Substitution - Missense	Central_nervous_system
COSM704904	c.1684G>A	p.E562K	Substitution - Missense	Lung
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Large_intestine
COSM4639415	c.1049G>A	p.R350Q	Substitution - Missense	Large_intestine
COSM1128821	c.3696T>G	p.T1232T	Substitution - coding silent	Prostate
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Upper_aerodigestive_tract
COSM2738961	c.5764A>C	p.R1922R	Substitution - coding silent	Upper_aerodigestive_tract
COSM4591233	c.534G>C	p.K178N	Substitution - Missense	Upper_aerodigestive_tract
COSM5897958	c.3943C>T	p.P1315S	Substitution - Missense	Skin
COSM5833227	c.4304_4305delAT	p.Y1435fs*1	Deletion - Frameshift	Breast
COSM1756932	c.2080C>T	p.R694*	Substitution - Nonsense	Urinary_tract
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM436090	c.3477A>T	p.P1159P	Substitution - coding silent	Breast
COSM4825673	c.5828C>T	p.S1943L	Substitution - Missense	Cervix
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Upper_aerodigestive_tract
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Upper_aerodigestive_tract
COSM4129611	c.447C>T	p.F149F	Substitution - coding silent	Upper_aerodigestive_tract
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM5712782	c.84A>G	p.T28T	Substitution - coding silent	Central_nervous_system
COSM1740355	c.5164A>C	p.K1722Q	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM162848	c.6899C>G	p.S2300*	Substitution - Nonsense	Breast
COSM3988787	c.7171C>G	p.R2391G	Substitution - Missense	Kidney
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM4960634	c.2549G>A	p.S850N	Substitution - Missense	Liver
COSM4960889	c.1095G>A	p.R365R	Substitution - coding silent	Liver
COSM5055243	c.1089G>A	p.G363G	Substitution - coding silent	Stomach
COSM5752306	c.1576_1577delGA	p.E526fs*9	Deletion - Frameshift	Breast
COSM472342	c.6411A>C	p.P2137P	Substitution - coding silent	Kidney
COSM4705986	c.2099A>G	p.E700G	Substitution - Missense	Large_intestine
COSM124695	c.509A>G	p.N170S	Substitution - Missense	Upper_aerodigestive_tract
COSM166128	c.3323_3324ins13	p.E1109fs*16	Insertion - Frameshift	Breast
COSM211943	c.6337C>G	p.Q2113E	Substitution - Missense	Breast
COSM436088	c.3823C>T	p.R1275*	Substitution - Nonsense	Breast
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM341088	c.1839G>A	p.P613P	Substitution - coding silent	Lung
COSM472348	c.2001T>C	p.F667F	Substitution - coding silent	Kidney
COSM4129609	c.568C>T	p.R190*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Upper_aerodigestive_tract
COSM3691375	c.3406G>A	p.A1136T	Substitution - Missense	Large_intestine
COSM5641107	c.6177C>T	p.I2059I	Substitution - coding silent	Oesophagus
COSM5722574	c.3450C>T	p.T1150T	Substitution - coding silent	Skin
COSM1258846	c.5742A>G	p.R1914R	Substitution - coding silent	Stomach
COSM460410	c.2779C>T	p.L927L	Substitution - coding silent	Cervix
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1381118	c.7022G>T	p.G2341V	Substitution - Missense	Large_intestine
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Upper_aerodigestive_tract
COSM3733523	c.14G>T	p.G5V	Substitution - Missense	Pancreas
COSM4064170	c.1381C>A	p.L461I	Substitution - Missense	Stomach
COSM3378087	c.1395C>G	p.Y465*	Substitution - Nonsense	Pancreas
COSM4591901	c.618+6T>A	p.?	Unknown	Upper_aerodigestive_tract
COSM5706304	c.1051A>T	p.K351*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM2739009	c.3649G>A	p.G1217R	Substitution - Missense	Upper_aerodigestive_tract
COSM4064160	c.4120A>G	p.T1374A	Substitution - Missense	Stomach
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Upper_aerodigestive_tract
COSM704903	c.1519C>A	p.R507R	Substitution - coding silent	Lung
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Central_nervous_system
COSM2738956	c.5867A>T	p.D1956V	Substitution - Missense	Large_intestine
COSM5016556	c.436-2delA	p.?	Unknown	Kidney
COSM3818885	c.5618T>G	p.V1873G	Substitution - Missense	Breast
COSM3421306	c.5572G>T	p.A1858S	Substitution - Missense	Large_intestine
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Upper_aerodigestive_tract
COSM4185536	c.2338G>A	p.V780M	Substitution - Missense	Kidney
COSM3514551	c.6640C>T	p.R2214C	Substitution - Missense	Skin
COSM3514570	c.196C>T	p.R66*	Substitution - Nonsense	Skin
COSM4263552	c.1192C>T	p.R398W	Substitution - Missense	Prostate
COSM249685	c.448G>A	p.G150R	Substitution - Missense	Large_intestine
COSM1302427	c.1408-1G>C	p.?	Unknown	Urinary_tract
COSM3514568	c.460G>A	p.E154K	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1381127	c.3440G>A	p.G1147E	Substitution - Missense	Large_intestine
COSM2739011	c.3563C>T	p.S1188L	Substitution - Missense	Large_intestine
COSM5986559	c.5790_5791insAAGCGCCC	p.N1931fs*6	Insertion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM4705979	c.6006G>A	p.A2002A	Substitution - coding silent	Large_intestine
COSM1216868	c.1060G>T	p.E354*	Substitution - Nonsense	Large_intestine
COSM162846	c.6838G>A	p.E2280K	Substitution - Missense	Breast
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Upper_aerodigestive_tract
COSM3733522	c.59A>C	p.Y20S	Substitution - Missense	Upper_aerodigestive_tract
COSM3514559	c.3429T>C	p.S1143S	Substitution - coding silent	Skin
COSM975879	c.3099G>A	p.P1033P	Substitution - coding silent	Stomach
COSM4129608	c.571G>A	p.E191K	Substitution - Missense	Upper_aerodigestive_tract
COSM3742096	c.155A>G	p.Q52R	Substitution - Missense	Liver
COSM1381136	c.2079G>A	p.E693E	Substitution - coding silent	Large_intestine
COSM5926971	c.439C>T	p.P147S	Substitution - Missense	Skin
COSM5967257	c.6728_6729insT	p.S2244fs*5	Insertion - Frameshift	Salivary_gland
COSM300095	c.738_739insA	p.A247fs*6	Insertion - Frameshift	Large_intestine
COSM300428	c.4257G>A	p.P1419P	Substitution - coding silent	Large_intestine
COSM3378086	c.2249C>T	p.A750V	Substitution - Missense	Pancreas
COSM1381130	c.2960G>A	p.C987Y	Substitution - Missense	Large_intestine
COSM5757974	c.2257C>G	p.L753V	Substitution - Missense	Bone
COSM4993948	c.2014C>T	p.R672*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM975876	c.3803C>T	p.P1268L	Substitution - Missense	Endometrium
COSM1630066	c.515C>T	p.S172L	Substitution - Missense	Thyroid
COSM5967256	c.6737C>G	p.S2246*	Substitution - Nonsense	Salivary_gland
COSM5605909	c.5814C>T	p.T1938T	Substitution - coding silent	Skin

> Text Mining based Variations

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PMID	Variation	Cancer	Evidence
25189356	Mutation	Prostate Carcinoma	From this genome-wide approach, mutations were found in a series of genes with prostate cancer relevance, including AR, NCOR1, KDM3A, KDM4A, CHD1, SETD5, SETD7, INPP4B, RASGRP3, RASA1, TP53BP1, and CDH1, and a novel SND1:BRAF gene fusion.

Summary
Symbol	NCOR1
Name	nuclear receptor corepressor 1
Aliases	N-CoR; hCIT529I10; hN-CoR; KIAA1047; MGC104216; PPP1R109; thyroid hormone- and retinoic acid receptor-associ ......
Location	17p12-p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

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Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant
O75376	224	S	Phosphoserine	-	No	None detected
O75376	999	S	Phosphoserine	-	No	None detected
O75376	1111	S	Phosphoserine	-	No	None detected
O75376	1195	S	Phosphoserine	-	No	None detected
O75376	1196	S	Phosphoserine	-	No	None detected
O75376	1249	S	Phosphoserine	-	No	None detected
O75376	1263	S	Phosphoserine	-	No	None detected
O75376	1281	S	Phosphoserine	-	No	None detected
O75376	1322	S	Phosphoserine	-	No	None detected
O75376	1336	K	N6-acetyllysine	-	No	None detected
O75376	1367	T	Phosphothreonine	-	No	None detected
O75376	1412	K	N6-acetyllysine	-	No	None detected
O75376	1450	S	Phosphoserine	-	No	None detected
O75376	1472	S	Phosphoserine	-	No	None detected
O75376	1592	S	Phosphoserine	-	No	None detected
O75376	1977	S	Phosphoserine	-	No	None detected
O75376	1981	S	Phosphoserine	-	Yes	p.S1981L (cancer: BLCA)
O75376	2102	S	Phosphoserine	-	No	None detected
O75376	2120	S	Phosphoserine	-	No	None detected
O75376	2136	S	Phosphoserine	-	No	None detected
O75376	2151	S	Phosphoserine	-	No	None detected
O75376	2184	S	Phosphoserine	-	No	None detected
O75376	2399	T	Phosphothreonine	-	No	None detected
O75376	2436	S	Phosphoserine	-	No	None detected
O75376	2438	S	Phosphoserine	-	No	None detected

Summary
Symbol	NCOR1
Name	nuclear receptor corepressor 1
Aliases	N-CoR; hCIT529I10; hN-CoR; KIAA1047; MGC104216; PPP1R109; thyroid hormone- and retinoic acid receptor-associ ......
Location	17p12-p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

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Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	6.696	6.042	-0.703	0.000253	Under
BRCA	Breast invasive carcinoma	112	1100	7.236	6.811	-0.402	7.87e-08	NS
CESC	Cervical and endocervical cancers	3	306	6.641	6.051	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	7.466	6.612	-0.816	2.63e-15	Under
ESCA	Esophageal carcinoma	11	185	7.882	7.544	-0.324	0.17	NS
GBM	Glioblastoma multiforme	5	166	6.75	6.235	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	6.699	6.242	-0.405	0.000399	NS
KIRC	Kidney renal clear cell carcinoma	72	534	7.309	6.764	-0.623	4.4e-18	Under
KIRP	Kidney renal papillary cell carcinoma	32	291	7.22	6.789	-0.425	0.00436	NS
LAML	Acute Myeloid Leukemia	0	173	NA	8.784	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	6.738	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	6.096	4.998	-1.141	5.89e-17	Under
LUAD	Lung adenocarcinoma	59	517	6.852	6.446	-0.316	0.000443	NS
LUSC	Lung squamous cell carcinoma	51	501	6.778	6.171	-0.579	5.59e-10	NS
OV	Ovarian serous cystadenocarcinoma	0	307	NA	6.545	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	6.348	6.203	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	5.821	5.79	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	6.967	6.579	-0.37	0.000273	NS
READ	Rectum adenocarcinoma	10	167	7.272	6.525	-0.607	0.00658	Under
SARC	Sarcoma	2	263	5.771	6.306	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	6.335	6.437	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	7.956	7.875	-0.006	0.968	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	6.517	NA	NA	NA
THCA	Thyroid carcinoma	59	509	6.919	6.711	-0.142	0.0661	NS
THYM	Thymoma	2	120	6.827	6.101	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	6.543	6.059	-0.5	2.74e-05	NS

> Cancer Cell Line Encyclopedia (CCLE)

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Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	8.2
Autonomic ganglia	CHP212	8
Autonomic ganglia	IMR32	8.5
Autonomic ganglia	KELLY	7.9
Autonomic ganglia	KPNRTBM1	8.4
Autonomic ganglia	KPNSI9S	7.7
Autonomic ganglia	KPNYN	7.4
Autonomic ganglia	MHHNB11	8.1
Autonomic ganglia	NB1	8.2
Autonomic ganglia	NH6	7.9
Autonomic ganglia	SHSY5Y	8.1
Autonomic ganglia	SIMA	8
Autonomic ganglia	SKNAS	7.1
Autonomic ganglia	SKNBE2	7.4
Autonomic ganglia	SKNDZ	8.5
Autonomic ganglia	SKNFI	8
Autonomic ganglia	SKNSH	7.7
Biliary tract	HUCCT1	7.7
Biliary tract	HUH28	8
Biliary tract	SNU1079	8.9
Biliary tract	SNU1196	8.1
Biliary tract	SNU245	8.2
Biliary tract	SNU308	7.5
Biliary tract	SNU478	7.7
Bone	143B	8.4
Bone	A673	8.2
Bone	CADOES1	8.8
Bone	CAL78	7.8
Bone	G292CLONEA141B1	10
Bone	HOS	8.3
Bone	HS706T	7.8
Bone	HS737T	7.7
Bone	HS819T	8
Bone	HS821T	8.2
Bone	HS822T	7.8
Bone	HS863T	8.4
Bone	HS870T	7.6
Bone	HS888T	8.3
Bone	MG63	7.1
Bone	MHHES1	8.5
Bone	OUMS27	8
Bone	RDES	8
Bone	SJSA1	7.8
Bone	SKES1	8.1
Bone	SKNMC	7.5
Bone	SW1353	8.2
Bone	T173	7.9
Bone	TC71	7.3
Bone	U2OS	7.3
Breast	AU565	7.7
Breast	BT20	8
Breast	BT474	7.9
Breast	BT483	7.5
Breast	BT549	8.2
Breast	CAL120	8.1
Breast	CAL148	8.9
Breast	CAL51	8.8
Breast	CAL851	7.9
Breast	CAMA1	7.7
Breast	DU4475	8.4
Breast	EFM192A	8.7
Breast	EFM19	6.3
Breast	EVSAT	7.6
Breast	HCC1143	7.6
Breast	HCC1187	7.5
Breast	HCC1395	7.6
Breast	HCC1419	8.5
Breast	HCC1428	8
Breast	HCC1500	7.5
Breast	HCC1569	7.7
Breast	HCC1599	7
Breast	HCC1806	8.3
Breast	HCC1937	7.7
Breast	HCC1954	7.5
Breast	HCC202	7.5
Breast	HCC2157	7
Breast	HCC2218	7
Breast	HCC38	7.9
Breast	HCC70	7.4
Breast	HDQP1	8.4
Breast	HMC18	8.2
Breast	HS274T	8.3
Breast	HS281T	8.1
Breast	HS343T	8.2
Breast	HS578T	7.8
Breast	HS606T	7.8
Breast	HS739T	7.8
Breast	HS742T	7.8
Breast	JIMT1	7.9
Breast	KPL1	8.1
Breast	MCF7	8
Breast	MDAMB134VI	6.9
Breast	MDAMB157	7.7
Breast	MDAMB175VII	7.3
Breast	MDAMB231	8
Breast	MDAMB361	7.4
Breast	MDAMB415	7.7
Breast	MDAMB436	7.2
Breast	MDAMB453	8.2
Breast	MDAMB468	7.1
Breast	SKBR3	7.6
Breast	T47D	7.3
Breast	UACC812	7.6
Breast	UACC893	7.2
Breast	YMB1	7.4
Breast	ZR751	6.8
Breast	ZR7530	7.7
Central nervous system	1321N1	7.7
Central nervous system	42MGBA	7.1
Central nervous system	8MGBA	7.2
Central nervous system	A172	8.2
Central nervous system	AM38	7.7
Central nervous system	BECKER	7.6
Central nervous system	CAS1	8
Central nervous system	CCFSTTG1	7.8
Central nervous system	D283MED	7.3
Central nervous system	D341MED	7.2
Central nervous system	DAOY	7.7
Central nervous system	DBTRG05MG	7.8
Central nervous system	DKMG	8.2
Central nervous system	GAMG	7.2
Central nervous system	GB1	8.5
Central nervous system	GI1	7.8
Central nervous system	GMS10	7.8
Central nervous system	GOS3	7.8
Central nervous system	H4	7.6
Central nervous system	HS683	7.9
Central nervous system	KALS1	7.1
Central nervous system	KG1C	7.6
Central nervous system	KNS42	8.4
Central nervous system	KNS60	8
Central nervous system	KNS81	8.2
Central nervous system	KS1	8.3
Central nervous system	LN18	7.8
Central nervous system	LN229	7.5
Central nervous system	M059K	6.9
Central nervous system	MOGGCCM	7.2
Central nervous system	MOGGUVW	7.9
Central nervous system	NMCG1	7.8
Central nervous system	ONS76	7.9
Central nervous system	SF126	7.8
Central nervous system	SF295	7.7
Central nervous system	SNB19	8.1
Central nervous system	SNU1105	8.1
Central nervous system	SNU201	8.4
Central nervous system	SNU466	7.7
Central nervous system	SNU489	7.9
Central nervous system	SNU626	8.2
Central nervous system	SNU738	8.7
Central nervous system	SW1088	7.6
Central nervous system	SW1783	7.6
Central nervous system	T98G	8
Central nervous system	TM31	9
Central nervous system	U118MG	7.8
Central nervous system	U138MG	7.8
Central nervous system	U251MG	8.7
Central nervous system	U87MG	7.8
Central nervous system	YH13	7.2
Central nervous system	YKG1	8.3
Endometrium	AN3CA	8.2
Endometrium	COLO684	8.3
Endometrium	EFE184	7.5
Endometrium	EN	7.4
Endometrium	ESS1	7.8
Endometrium	HEC108	8.2
Endometrium	HEC151	7.1
Endometrium	HEC1A	8.2
Endometrium	HEC1B	8.5
Endometrium	HEC251	7.9
Endometrium	HEC265	7.7
Endometrium	HEC50B	8.1
Endometrium	HEC59	7.9
Endometrium	HEC6	8.6
Endometrium	ISHIKAWAHERAKLIO02ER	8.1
Endometrium	JHUEM1	8.3
Endometrium	JHUEM2	8.5
Endometrium	JHUEM3	7.8
Endometrium	KLE	6.3
Endometrium	MFE280	7.6
Endometrium	MFE296	8.2
Endometrium	MFE319	7.4
Endometrium	RL952	7.9
Endometrium	SNGM	8.2
Endometrium	SNU1077	7.7
Endometrium	SNU685	8.3
Endometrium	TEN	7.5
Haematopoietic and lymphoid	697	9
Haematopoietic and lymphoid	A3KAW	7.8
Haematopoietic and lymphoid	A4FUK	7.9
Haematopoietic and lymphoid	ALLSIL	9
Haematopoietic and lymphoid	AML193	7.7
Haematopoietic and lymphoid	AMO1	8.5
Haematopoietic and lymphoid	BCP1	8.1
Haematopoietic and lymphoid	BDCM	8.1
Haematopoietic and lymphoid	BL41	7.8
Haematopoietic and lymphoid	BL70	8.2
Haematopoietic and lymphoid	BV173	9.4
Haematopoietic and lymphoid	CA46	7.9
Haematopoietic and lymphoid	CI1	8.3
Haematopoietic and lymphoid	CMK115	8.5
Haematopoietic and lymphoid	CMK86	8.6
Haematopoietic and lymphoid	CMK	8.6
Haematopoietic and lymphoid	CMLT1	9.1
Haematopoietic and lymphoid	COLO775	7.7
Haematopoietic and lymphoid	DAUDI	8
Haematopoietic and lymphoid	DB	8.2
Haematopoietic and lymphoid	DEL	8
Haematopoietic and lymphoid	DND41	8.8
Haematopoietic and lymphoid	DOHH2	8.5
Haematopoietic and lymphoid	EB1	8.4
Haematopoietic and lymphoid	EB2	8
Haematopoietic and lymphoid	EHEB	8.1
Haematopoietic and lymphoid	EJM	8.1
Haematopoietic and lymphoid	EM2	8.3
Haematopoietic and lymphoid	EOL1	8.7
Haematopoietic and lymphoid	F36P	7.8
Haematopoietic and lymphoid	GA10	7.8
Haematopoietic and lymphoid	GDM1	8.3
Haematopoietic and lymphoid	GRANTA519	7.7
Haematopoietic and lymphoid	HDLM2	8.6
Haematopoietic and lymphoid	HDMYZ	7.7
Haematopoietic and lymphoid	HEL9217	8
Haematopoietic and lymphoid	HEL	8.2
Haematopoietic and lymphoid	HH	8.1
Haematopoietic and lymphoid	HL60	7.8
Haematopoietic and lymphoid	HPBALL	9
Haematopoietic and lymphoid	HS604T	8.1
Haematopoietic and lymphoid	HS611T	8.1
Haematopoietic and lymphoid	HS616T	8.2
Haematopoietic and lymphoid	HS751T	8.1
Haematopoietic and lymphoid	HT	8.2
Haematopoietic and lymphoid	HTK	8.5
Haematopoietic and lymphoid	HUNS1	8
Haematopoietic and lymphoid	HUT102	8.1
Haematopoietic and lymphoid	HUT78	8
Haematopoietic and lymphoid	JEKO1	7.6
Haematopoietic and lymphoid	JK1	8.5
Haematopoietic and lymphoid	JM1	8.2
Haematopoietic and lymphoid	JURKAT	9.3
Haematopoietic and lymphoid	JURLMK1	7.9
Haematopoietic and lymphoid	JVM2	8.2
Haematopoietic and lymphoid	JVM3	8.6
Haematopoietic and lymphoid	K562	7.5
Haematopoietic and lymphoid	KARPAS299	7.7
Haematopoietic and lymphoid	KARPAS422	8
Haematopoietic and lymphoid	KARPAS620	8.5
Haematopoietic and lymphoid	KASUMI1	7.3
Haematopoietic and lymphoid	KASUMI2	8.9
Haematopoietic and lymphoid	KASUMI6	7.7
Haematopoietic and lymphoid	KCL22	7.7
Haematopoietic and lymphoid	KE37	9.1
Haematopoietic and lymphoid	KE97	7.9
Haematopoietic and lymphoid	KG1	7.6
Haematopoietic and lymphoid	KHM1B	7.5
Haematopoietic and lymphoid	KIJK	7
Haematopoietic and lymphoid	KMH2	8.3
Haematopoietic and lymphoid	KMM1	8.1
Haematopoietic and lymphoid	KMS11	7.6
Haematopoietic and lymphoid	KMS12BM	7.7
Haematopoietic and lymphoid	KMS18	8.5
Haematopoietic and lymphoid	KMS20	7.4
Haematopoietic and lymphoid	KMS21BM	7.7
Haematopoietic and lymphoid	KMS26	10
Haematopoietic and lymphoid	KMS27	7.5
Haematopoietic and lymphoid	KMS28BM	8
Haematopoietic and lymphoid	KMS34	8.2
Haematopoietic and lymphoid	KO52	7.7
Haematopoietic and lymphoid	KOPN8	8.8
Haematopoietic and lymphoid	KU812	8.3
Haematopoietic and lymphoid	KYO1	8.7
Haematopoietic and lymphoid	L1236	7.8
Haematopoietic and lymphoid	L363	7.2
Haematopoietic and lymphoid	L428	8.9
Haematopoietic and lymphoid	L540	8.3
Haematopoietic and lymphoid	LAMA84	8.4
Haematopoietic and lymphoid	LOUCY	8.8
Haematopoietic and lymphoid	LP1	8.1
Haematopoietic and lymphoid	M07E	9.1
Haematopoietic and lymphoid	MC116	8.1
Haematopoietic and lymphoid	ME1	7.8
Haematopoietic and lymphoid	MEC1	7.7
Haematopoietic and lymphoid	MEC2	7.9
Haematopoietic and lymphoid	MEG01	7.6
Haematopoietic and lymphoid	MHHCALL2	8.8
Haematopoietic and lymphoid	MHHCALL3	8.9
Haematopoietic and lymphoid	MHHCALL4	8.8
Haematopoietic and lymphoid	MINO	8.6
Haematopoietic and lymphoid	MJ	8.4
Haematopoietic and lymphoid	MM1S	8.1
Haematopoietic and lymphoid	MOLM13	8.7
Haematopoietic and lymphoid	MOLM16	9
Haematopoietic and lymphoid	MOLM6	8.6
Haematopoietic and lymphoid	MOLP2	8.8
Haematopoietic and lymphoid	MOLP8	8.7
Haematopoietic and lymphoid	MOLT13	8.8
Haematopoietic and lymphoid	MOLT16	9.7
Haematopoietic and lymphoid	MOLT4	7.9
Haematopoietic and lymphoid	MONOMAC1	8
Haematopoietic and lymphoid	MONOMAC6	8.2
Haematopoietic and lymphoid	MOTN1	8
Haematopoietic and lymphoid	MUTZ5	8.8
Haematopoietic and lymphoid	MV411	8.7
Haematopoietic and lymphoid	NALM19	8.9
Haematopoietic and lymphoid	NALM1	8.8
Haematopoietic and lymphoid	NALM6	8.3
Haematopoietic and lymphoid	NAMALWA	7.6
Haematopoietic and lymphoid	NB4	8.9
Haematopoietic and lymphoid	NCIH929	7.1
Haematopoietic and lymphoid	NCO2	8.4
Haematopoietic and lymphoid	NOMO1	8.6
Haematopoietic and lymphoid	NUDHL1	8.3
Haematopoietic and lymphoid	NUDUL1	8.4
Haematopoietic and lymphoid	OCIAML2	9.1
Haematopoietic and lymphoid	OCIAML3	9
Haematopoietic and lymphoid	OCIAML5	8.8
Haematopoietic and lymphoid	OCILY10	7.9
Haematopoietic and lymphoid	OCILY19	8.6
Haematopoietic and lymphoid	OCILY3	7.3
Haematopoietic and lymphoid	OCIM1	8.3
Haematopoietic and lymphoid	OPM2	8.6
Haematopoietic and lymphoid	P12ICHIKAWA	9.2
Haematopoietic and lymphoid	P31FUJ	8.1
Haematopoietic and lymphoid	P3HR1	8
Haematopoietic and lymphoid	PCM6	7.2
Haematopoietic and lymphoid	PEER	8.7
Haematopoietic and lymphoid	PF382	9
Haematopoietic and lymphoid	PFEIFFER	7.8
Haematopoietic and lymphoid	PL21	8.7
Haematopoietic and lymphoid	RAJI	7.7
Haematopoietic and lymphoid	RCHACV	6.6
Haematopoietic and lymphoid	REC1	8.6
Haematopoietic and lymphoid	REH	8.5
Haematopoietic and lymphoid	RI1	8.3
Haematopoietic and lymphoid	RL	7.1
Haematopoietic and lymphoid	RPMI8226	7.6
Haematopoietic and lymphoid	RPMI8402	9.5
Haematopoietic and lymphoid	RS411	8.4
Haematopoietic and lymphoid	SEM	8.6
Haematopoietic and lymphoid	SET2	8.5
Haematopoietic and lymphoid	SIGM5	8.5
Haematopoietic and lymphoid	SKM1	8.4
Haematopoietic and lymphoid	SKMM2	8.3
Haematopoietic and lymphoid	SR786	8.5
Haematopoietic and lymphoid	ST486	8
Haematopoietic and lymphoid	SUDHL10	8
Haematopoietic and lymphoid	SUDHL1	8.2
Haematopoietic and lymphoid	SUDHL4	8.3
Haematopoietic and lymphoid	SUDHL5	8.3
Haematopoietic and lymphoid	SUDHL6	8.6
Haematopoietic and lymphoid	SUDHL8	8.1
Haematopoietic and lymphoid	SUPB15	8.3
Haematopoietic and lymphoid	SUPHD1	8.3
Haematopoietic and lymphoid	SUPM2	7.7
Haematopoietic and lymphoid	SUPT11	8.2
Haematopoietic and lymphoid	SUPT1	8.2
Haematopoietic and lymphoid	TALL1	8.9
Haematopoietic and lymphoid	TF1	8
Haematopoietic and lymphoid	THP1	7.7
Haematopoietic and lymphoid	TO175T	8.1
Haematopoietic and lymphoid	TOLEDO	7.3
Haematopoietic and lymphoid	U266B1	7.1
Haematopoietic and lymphoid	U937	8.5
Haematopoietic and lymphoid	UT7	8.2
Haematopoietic and lymphoid	WSUDLCL2	8.6
Kidney	769P	8.3
Kidney	786O	7.8
Kidney	A498	8
Kidney	A704	7.5
Kidney	ACHN	8.5
Kidney	BFTC909	8.5
Kidney	CAKI1	7.5
Kidney	CAKI2	7.1
Kidney	CAL54	8.7
Kidney	KMRC1	7.8
Kidney	KMRC20	7.2
Kidney	KMRC2	7.7
Kidney	KMRC3	7.8
Kidney	OSRC2	8.1
Kidney	RCC10RGB	8.2
Kidney	SNU1272	8
Kidney	SNU349	7.4
Kidney	TUHR10TKB	7.3
Kidney	TUHR14TKB	8.1
Kidney	TUHR4TKB	8.1
Kidney	VMRCRCW	8.2
Kidney	VMRCRCZ	7.3
Large intestine	C2BBE1	7.5
Large intestine	CCK81	7.6
Large intestine	CL11	7.9
Large intestine	CL14	7.9
Large intestine	CL34	9.2
Large intestine	CL40	8.7
Large intestine	COLO205	8.8
Large intestine	COLO320	8.1
Large intestine	COLO678	8.9
Large intestine	CW2	8.2
Large intestine	DLD1	7.1
Large intestine	GP2D	8.2
Large intestine	HCC56	7.8
Large intestine	HCT116	6.3
Large intestine	HCT15	7.9
Large intestine	HS675T	8
Large intestine	HS698T	8.4
Large intestine	HT115	8.8
Large intestine	HT29	7.9
Large intestine	HT55	9
Large intestine	KM12	8.3
Large intestine	LOVO	8.1
Large intestine	LS1034	8.1
Large intestine	LS123	7.7
Large intestine	LS180	8.9
Large intestine	LS411N	8.7
Large intestine	LS513	8.3
Large intestine	MDST8	8.3
Large intestine	NCIH508	8.4
Large intestine	NCIH716	8.2
Large intestine	NCIH747	6.8
Large intestine	OUMS23	8.2
Large intestine	RCM1	7.9
Large intestine	RKO	6.5
Large intestine	SKCO1	8.2
Large intestine	SNU1040	8.7
Large intestine	SNU1197	6.9
Large intestine	SNU175	9
Large intestine	SNU283	4.6
Large intestine	SNU407	8.5
Large intestine	SNU503	7.7
Large intestine	SNU61	8.3
Large intestine	SNU81	9.3
Large intestine	SNUC1	8.3
Large intestine	SNUC2A	8.1
Large intestine	SNUC4	8.7
Large intestine	SNUC5	7.8
Large intestine	SW1116	7.7
Large intestine	SW1417	7.6
Large intestine	SW1463	7.9
Large intestine	SW403	8.4
Large intestine	SW480	8.1
Large intestine	SW48	7.9
Large intestine	SW620	8.2
Large intestine	SW837	7.3
Large intestine	SW948	9
Large intestine	T84	7.6
Liver	ALEXANDERCELLS	7.6
Liver	C3A	8
Liver	HEP3B217	8.1
Liver	HEPG2	7.9
Liver	HLE	8.7
Liver	HLF	8.4
Liver	HUH1	8.1
Liver	HUH6	7.6
Liver	HUH7	8
Liver	JHH1	6.9
Liver	JHH2	7.3
Liver	JHH4	7.6
Liver	JHH5	8.2
Liver	JHH6	7.9
Liver	JHH7	7.9
Liver	LI7	8.2
Liver	PLCPRF5	7.6
Liver	SKHEP1	8.3
Liver	SNU182	9.7
Liver	SNU387	7.4
Liver	SNU398	8.8
Liver	SNU423	7.8
Liver	SNU449	7.9
Liver	SNU475	7.8
Liver	SNU761	7.8
Liver	SNU878	7.5
Liver	SNU886	8.5
Lung	A549	8.5
Lung	ABC1	7.9
Lung	BEN	8.1
Lung	CAL12T	7.6
Lung	CALU1	7.6
Lung	CALU3	7.5
Lung	CALU6	8.1
Lung	CHAGOK1	7.9
Lung	COLO668	7.7
Lung	COLO699	7.5
Lung	CORL105	7.5
Lung	CORL23	7.4
Lung	CORL24	8
Lung	CORL279	7.5
Lung	CORL311	8.8
Lung	CORL47	6.9
Lung	CORL51	8.1
Lung	CORL88	7.5
Lung	CORL95	7.6
Lung	CPCN	8.1
Lung	DMS114	6.7
Lung	DMS153	6.9
Lung	DMS273	7.3
Lung	DMS454	7.2
Lung	DMS53	7.3
Lung	DMS79	7.2
Lung	DV90	8
Lung	EBC1	7.8
Lung	EPLC272H	7.3
Lung	HARA	7.8
Lung	HCC1171	8
Lung	HCC1195	7.4
Lung	HCC15	7.7
Lung	HCC2279	8
Lung	HCC2935	8.3
Lung	HCC33	8
Lung	HCC366	7
Lung	HCC4006	8.1
Lung	HCC44	7.4
Lung	HCC78	7.5
Lung	HCC827	8.5
Lung	HCC95	7.9
Lung	HLC1	8.3
Lung	HLFA	7.9
Lung	HS229T	8
Lung	HS618T	7.8
Lung	IALM	7.7
Lung	KNS62	7.7
Lung	LC1F	8.2
Lung	LC1SQSF	7.9
Lung	LCLC103H	8.1
Lung	LCLC97TM1	7.9
Lung	LK2	7.6
Lung	LOUNH91	7.8
Lung	LU65	7.7
Lung	LU99	7.6
Lung	LUDLU1	7.8
Lung	LXF289	8.1
Lung	MORCPR	8.1
Lung	NCIH1048	8.4
Lung	NCIH1092	7.8
Lung	NCIH1105	8.5
Lung	NCIH1155	7.8
Lung	NCIH1184	8.2
Lung	NCIH1299	8.3
Lung	NCIH1339	7.8
Lung	NCIH1341	7.6
Lung	NCIH1355	8.1
Lung	NCIH1373	7.5
Lung	NCIH1385	8.7
Lung	NCIH1395	7.5
Lung	NCIH1435	7.8
Lung	NCIH1436	8.3
Lung	NCIH1437	8.1
Lung	NCIH146	7.6
Lung	NCIH1563	7.5
Lung	NCIH1568	7.4
Lung	NCIH1573	8.3
Lung	NCIH1581	7.7
Lung	NCIH1618	8.3
Lung	NCIH1623	7.9
Lung	NCIH1648	7.5
Lung	NCIH1650	7.7
Lung	NCIH1651	7.8
Lung	NCIH1666	6.8
Lung	NCIH1693	7.6
Lung	NCIH1694	8
Lung	NCIH1703	8.9
Lung	NCIH1734	6.8
Lung	NCIH1755	6.8
Lung	NCIH1781	7.5
Lung	NCIH1792	6.9
Lung	NCIH1793	7.6
Lung	NCIH1836	7.9
Lung	NCIH1838	8.7
Lung	NCIH1869	7.6
Lung	NCIH1876	8.4
Lung	NCIH1915	7.8
Lung	NCIH1930	7.7
Lung	NCIH1944	7.5
Lung	NCIH1963	8.1
Lung	NCIH196	7.2
Lung	NCIH1975	8.1
Lung	NCIH2009	8
Lung	NCIH2023	7.3
Lung	NCIH2029	7.2
Lung	NCIH2030	7.8
Lung	NCIH2066	8.4
Lung	NCIH2081	7.4
Lung	NCIH2085	7.8
Lung	NCIH2087	7.7
Lung	NCIH209	7.8
Lung	NCIH2106	7.1
Lung	NCIH2110	8.2
Lung	NCIH211	7.2
Lung	NCIH2122	7.9
Lung	NCIH2126	7.9
Lung	NCIH2141	7.9
Lung	NCIH2170	7.8
Lung	NCIH2171	7.6
Lung	NCIH2172	8.1
Lung	NCIH2196	6.8
Lung	NCIH2227	7.9
Lung	NCIH2228	6.4
Lung	NCIH226	7.6
Lung	NCIH2286	8.3
Lung	NCIH2291	7
Lung	NCIH2342	7.4
Lung	NCIH2347	6.6
Lung	NCIH23	8.7
Lung	NCIH2405	7.6
Lung	NCIH2444	7.2
Lung	NCIH292	8
Lung	NCIH322	8.1
Lung	NCIH3255	8
Lung	NCIH358	7.9
Lung	NCIH441	8.2
Lung	NCIH446	7.1
Lung	NCIH460	7.8
Lung	NCIH510	7.8
Lung	NCIH520	6.8
Lung	NCIH522	7.2
Lung	NCIH524	7.9
Lung	NCIH526	7.6
Lung	NCIH596	7.8
Lung	NCIH647	7.8
Lung	NCIH650	8.9
Lung	NCIH661	8.2
Lung	NCIH69	7.1
Lung	NCIH727	8.2
Lung	NCIH810	7.5
Lung	NCIH82	8.4
Lung	NCIH838	7.1
Lung	NCIH841	7.5
Lung	NCIH854	8.3
Lung	NCIH889	6.9
Lung	PC14	8.1
Lung	RERFLCAD1	8.4
Lung	RERFLCAD2	6.9
Lung	RERFLCAI	8.1
Lung	RERFLCKJ	8.4
Lung	RERFLCMS	7.5
Lung	RERFLCSQ1	8
Lung	SBC5	8
Lung	SCLC21H	7.5
Lung	SHP77	9.6
Lung	SKLU1	7.9
Lung	SKMES1	6.7
Lung	SQ1	7.2
Lung	SW1271	8.9
Lung	SW1573	8.7
Lung	SW900	7.2
Lung	VMRCLCD	8.1
Lung	VMRCLCP	7.2
Oesophagus	COLO680N	8.1
Oesophagus	ECGI10	8.8
Oesophagus	KYSE140	7.7
Oesophagus	KYSE150	8.3
Oesophagus	KYSE180	7.3
Oesophagus	KYSE270	7.6
Oesophagus	KYSE30	9.2
Oesophagus	KYSE410	7.9
Oesophagus	KYSE450	7.9
Oesophagus	KYSE510	7.7
Oesophagus	KYSE520	7.8
Oesophagus	KYSE70	7.9
Oesophagus	OE19	9
Oesophagus	OE33	7.4
Oesophagus	TE10	9
Oesophagus	TE11	7.3
Oesophagus	TE14	7.9
Oesophagus	TE15	7.9
Oesophagus	TE1	7.3
Oesophagus	TE4	10.3
Oesophagus	TE5	7.7
Oesophagus	TE6	8.4
Oesophagus	TE8	7.8
Oesophagus	TE9	8.1
Oesophagus	TT	8.4
Ovary	59M	7.8
Ovary	A2780	8.2
Ovary	CAOV3	7
Ovary	CAOV4	7.8
Ovary	COLO704	7.9
Ovary	COV318	7.1
Ovary	COV362	7.1
Ovary	COV434	8.4
Ovary	COV504	7.6
Ovary	COV644	7.8
Ovary	EFO21	7.7
Ovary	EFO27	8
Ovary	ES2	7.3
Ovary	FUOV1	7.3
Ovary	HEYA8	7.6
Ovary	HS571T	7.5
Ovary	IGROV1	8
Ovary	JHOC5	7.7
Ovary	JHOM1	8
Ovary	JHOM2B	7.7
Ovary	JHOS2	7.2
Ovary	JHOS4	7.3
Ovary	KURAMOCHI	7.7
Ovary	MCAS	7.1
Ovary	NIHOVCAR3	8.1
Ovary	OAW28	6.9
Ovary	OAW42	7.8
Ovary	OC314	8
Ovary	OC316	7.9
Ovary	ONCODG1	8.6
Ovary	OV56	7.9
Ovary	OV7	7.8
Ovary	OV90	8.5
Ovary	OVCAR4	7.1
Ovary	OVCAR8	7.8
Ovary	OVISE	6.7
Ovary	OVK18	8.5
Ovary	OVKATE	6.7
Ovary	OVMANA	7.2
Ovary	OVSAHO	7.1
Ovary	OVTOKO	7.5
Ovary	RMGI	6.4
Ovary	RMUGS	6.7
Ovary	SKOV3	7.1
Ovary	SNU119	7.8
Ovary	SNU840	7.6
Ovary	SNU8	7.3
Ovary	TOV112D	8.3
Ovary	TOV21G	7.9
Ovary	TYKNU	7.6
Pancreas	ASPC1	8.4
Pancreas	BXPC3	7.2
Pancreas	CAPAN1	7.8
Pancreas	CAPAN2	7.1
Pancreas	CFPAC1	6.8
Pancreas	DANG	7.1
Pancreas	HPAC	8.3
Pancreas	HPAFII	7.8
Pancreas	HS766T	7.3
Pancreas	HUPT3	7.6
Pancreas	HUPT4	7.4
Pancreas	KCIMOH1	8.1
Pancreas	KLM1	7.8
Pancreas	KP2	7.5
Pancreas	KP3	8
Pancreas	KP4	8.4
Pancreas	L33	7.3
Pancreas	MIAPACA2	8.4
Pancreas	PANC0203	7.3
Pancreas	PANC0213	6.9
Pancreas	PANC0327	7.5
Pancreas	PANC0403	7.7
Pancreas	PANC0504	7.8
Pancreas	PANC0813	6.9
Pancreas	PANC1005	7.2
Pancreas	PANC1	7.5
Pancreas	PATU8902	7.4
Pancreas	PATU8988S	7.1
Pancreas	PATU8988T	7.6
Pancreas	PK1	8.2
Pancreas	PK45H	7.8
Pancreas	PK59	7.7
Pancreas	PL45	7.2
Pancreas	PSN1	7.7
Pancreas	QGP1	8.6
Pancreas	SNU213	7.2
Pancreas	SNU324	7.8
Pancreas	SNU410	7.6
Pancreas	SU8686	8.4
Pancreas	SUIT2	8.5
Pancreas	SW1990	6.9
Pancreas	T3M4	7.3
Pancreas	TCCPAN2	7.6
Pancreas	YAPC	7.7
Pleura	ACCMESO1	7.6
Pleura	DM3	8.3
Pleura	ISTMES1	7.7
Pleura	ISTMES2	7.1
Pleura	JL1	8.5
Pleura	MPP89	7.4
Pleura	MSTO211H	8.2
Pleura	NCIH2052	7.8
Pleura	NCIH2452	7.8
Pleura	NCIH28	7.9
Prostate	22RV1	8.7
Prostate	DU145	6.6
Prostate	LNCAPCLONEFGC	8.4
Prostate	MDAPCA2B	7.8
Prostate	NCIH660	7.8
Prostate	PC3	7.5
Prostate	VCAP	8.5
Salivary gland	A253	8.4
Salivary gland	YD15	8.2
Skin	A101D	7.4
Skin	A2058	8.2
Skin	A375	7.5
Skin	C32	7.5
Skin	CHL1	7.5
Skin	CJM	7.4
Skin	COLO679	7.4
Skin	COLO741	7.7
Skin	COLO783	8
Skin	COLO792	6.9
Skin	COLO800	7.6
Skin	COLO818	7.3
Skin	COLO829	7.4
Skin	COLO849	7.5
Skin	G361	6.9
Skin	GRM	7.7
Skin	HMCB	7.8
Skin	HS294T	7.3
Skin	HS600T	7.7
Skin	HS688AT	7.9
Skin	HS695T	7.6
Skin	HS839T	7.9
Skin	HS852T	6.9
Skin	HS895T	7.5
Skin	HS934T	8.3
Skin	HS936T	6.9
Skin	HS939T	7.3
Skin	HS940T	8.1
Skin	HS944T	7
Skin	HT144	7.8
Skin	IGR1	8.1
Skin	IGR37	6.4
Skin	IGR39	7.7
Skin	IPC298	6.6
Skin	K029AX	7.6
Skin	LOXIMVI	8.3
Skin	MALME3M	7.4
Skin	MDAMB435S	7.2
Skin	MELHO	6.8
Skin	MELJUSO	7.6
Skin	MEWO	7.7
Skin	RPMI7951	7.9
Skin	RVH421	7.3
Skin	SH4	8
Skin	SKMEL1	7.5
Skin	SKMEL24	7.4
Skin	SKMEL28	7.6
Skin	SKMEL2	6.2
Skin	SKMEL30	7.2
Skin	SKMEL31	7.5
Skin	SKMEL3	7
Skin	SKMEL5	7.5
Skin	UACC257	7.3
Skin	UACC62	7.1
Skin	WM115	7.5
Skin	WM1799	8.2
Skin	WM2664	7.4
Skin	WM793	7.6
Skin	WM88	7.7
Skin	WM983B	7.4
Small intestine	HUTU80	8.4
Soft tissue	A204	7.6
Soft tissue	G401	8.1
Soft tissue	G402	8.2
Soft tissue	GCT	7.6
Soft tissue	HS729	8.2
Soft tissue	HT1080	7.4
Soft tissue	KYM1	8.5
Soft tissue	MESSA	8
Soft tissue	RD	7.6
Soft tissue	RH30	8.5
Soft tissue	RH41	8.5
Soft tissue	RKN	7.9
Soft tissue	S117	7.3
Soft tissue	SJRH30	9.1
Soft tissue	SKLMS1	7.5
Soft tissue	SKUT1	8.4
Soft tissue	TE125T	8
Soft tissue	TE159T	7.9
Soft tissue	TE441T	8.8
Soft tissue	TE617T	8.3
Stomach	2313287	8.7
Stomach	AGS	8.1
Stomach	AZ521	8.8
Stomach	ECC10	8.6
Stomach	ECC12	7.4
Stomach	FU97	6.1
Stomach	GCIY	7.5
Stomach	GSS	8.2
Stomach	GSU	9
Stomach	HGC27	8.1
Stomach	HS746T	8
Stomach	HUG1N	8.1
Stomach	IM95	8.9
Stomach	KATOIII	7.8
Stomach	KE39	7.8
Stomach	LMSU	8.2
Stomach	MKN1	7.7
Stomach	MKN45	9.1
Stomach	MKN74	7.8
Stomach	MKN7	7.5
Stomach	NCCSTCK140	8.6
Stomach	NCIN87	7.4
Stomach	NUGC2	7.7
Stomach	NUGC3	7.5
Stomach	NUGC4	8.2
Stomach	OCUM1	8.5
Stomach	RERFGC1B	7.5
Stomach	SH10TC	7.7
Stomach	SNU16	8.3
Stomach	SNU1	7.6
Stomach	SNU216	8.5
Stomach	SNU520	8.9
Stomach	SNU5	7.5
Stomach	SNU601	9
Stomach	SNU620	8.3
Stomach	SNU668	8
Stomach	SNU719	9.1
Stomach	TGBC11TKB	8.7
Thyroid	8305C	8
Thyroid	8505C	8.1
Thyroid	BCPAP	7.8
Thyroid	BHT101	7.8
Thyroid	CAL62	8.5
Thyroid	CGTHW1	7.7
Thyroid	FTC133	7.7
Thyroid	FTC238	7.6
Thyroid	ML1	7.5
Thyroid	SW579	7.5
Thyroid	TT2609C02	7.7
Thyroid	TT	8.1
Upper aerodigestive tract	BHY	7.4
Upper aerodigestive tract	BICR16	7.2
Upper aerodigestive tract	BICR18	7.3
Upper aerodigestive tract	BICR22	7.9
Upper aerodigestive tract	BICR31	7.3
Upper aerodigestive tract	BICR56	8
Upper aerodigestive tract	BICR6	7.9
Upper aerodigestive tract	CAL27	7.5
Upper aerodigestive tract	CAL33	7.9
Upper aerodigestive tract	DETROIT562	7.7
Upper aerodigestive tract	FADU	8.1
Upper aerodigestive tract	HS840T	7.8
Upper aerodigestive tract	HSC2	7.9
Upper aerodigestive tract	HSC3	7.8
Upper aerodigestive tract	HSC4	8.6
Upper aerodigestive tract	PECAPJ15	7.7
Upper aerodigestive tract	PECAPJ34CLONEC12	7.9
Upper aerodigestive tract	PECAPJ41CLONED2	7.9
Upper aerodigestive tract	PECAPJ49	7.6
Upper aerodigestive tract	SCC15	8.1
Upper aerodigestive tract	SCC25	7.6
Upper aerodigestive tract	SCC4	7.7
Upper aerodigestive tract	SCC9	7.7
Upper aerodigestive tract	SNU1076	7.9
Upper aerodigestive tract	SNU1214	7.8
Upper aerodigestive tract	SNU46	8.2
Upper aerodigestive tract	SNU899	8
Upper aerodigestive tract	YD10B	8.1
Upper aerodigestive tract	YD38	8.5
Upper aerodigestive tract	YD8	8.6
Urinary tract	5637	7.3
Urinary tract	639V	8.6
Urinary tract	647V	7.8
Urinary tract	BC3C	7.7
Urinary tract	BFTC905	7.7
Urinary tract	CAL29	7.5
Urinary tract	HS172T	8
Urinary tract	HT1197	7.6
Urinary tract	HT1376	7.4
Urinary tract	J82	7.4
Urinary tract	JMSU1	7.7
Urinary tract	KMBC2	8.5
Urinary tract	KU1919	8
Urinary tract	RT11284	8.4
Urinary tract	RT112	8.6
Urinary tract	RT4	7.7
Urinary tract	SCABER	6.8
Urinary tract	SW1710	8.1
Urinary tract	SW780	8.2
Urinary tract	T24	8.1
Urinary tract	TCCSUP	8.6
Urinary tract	UMUC1	7.3
Urinary tract	UMUC3	8.1
Urinary tract	VMCUB1	7.4

> The Human Protein Atlas (HPA)

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Tissue	Expression Level (TPM)
Adipose tissue	25.3
Adrenal gland	24
Appendix	38.4
Bone marrow	27.7
Breast	35.9
Cerebral cortex	44.4
Cervix, uterine	42
Colon	44.1
Duodenum	48.5
Endometrium	49.7
Epididymis	26.6
Esophagus	33.9
Fallopian tube	40.8
Gallbladder	41.7
Heart muscle	15.3
Kidney	36.9
Liver	24.4
Lung	40.5
Lymph node	35.3
Ovary	41.6
Pancreas	7.2
Parathyroid gland	84
Placenta	39.9
Prostate	44.9
Rectum	45
Salivary gland	9.6
Seminal vesicle	44.1
Skeletal muscle	14.6
Skin	37.4
Small intestine	42.6
Smooth muscle	43.1
Spleen	40.8
Stomach	39.9
Testis	59.9
Thyroid gland	57.6
Tonsil	32.8
Urinary bladder	34

> Text Mining based Expression

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PMID	Expression	Cancer	Evidence
21143702	Underexpression	Glioma	In contrast, weak expression of NCOR1 and HDAC3 was detected in the cytoplasm and nuclei of tumor cells.
26968201	Underexpression	Prostate Carcinoma	Prostate cancer metastases show significant decrease in NCOR1 transcriptional output.
26589942	Underexpression	Gastric Carcinoma	We found that the PDCD2 and NCoR1 protein levels were lower in gastric GIST tissues than in normal gastric tissues.
23295231	Aberrant Expression	Retinoblastoma	The aberrant cytoplasmic expression of NCoR1 in retinoblastoma appears to be associated with the proliferative and/or dedifferentiated properties of retinoblastoma.
21966475	Aberrant expression	Non-Small Cell Lung Cancer	Indeed, our initial screening of N-CoR status in various leukemia and solid tumor cells revealed an APL like MCDL of N-CoR in primary and secondary tumor cells derived from non-small cell lung cancer (NSCLC).
17823926	Overexpression	Multiple Myeloma	The analysis of transcriptional profiles in a proprietary database of myeloma cell lines identified 12 significantly overexpressed genes in the KMS-26 amplified region, including TNFRSF13B/TACI, COPS3, and NCOR1.
17630505	Aberrant Expression	Colorectal Carcinoma	Moreover, we have analyzed the subcellular localization of N-CoR in 43 colorectal cancer samples and we have found that aberrant cytoplasmic distribution of N-CoR is a general trait of these tumors.
16019133	altered expression	Breast Carcinoma	It was found that NCOR1 mRNA was expressed at significantly higher levels in patients over 50 years of age, without axillary lymph node involvement, with tumor size less than 2 cm, with low or intermediate histological grade, with ERalpha/PgR-positive and with HER2 negative tumors.
12684393	Underexpression	Breast Carcinoma	Low NCOR1 expression (versus intermediate and high) was associated with significantly shorter relapse-free survival (log-rank test; P = 0.0076).
28521442	Underexpression	Gastric Carcinoma	Significantly decreased levels of STS, HSD3B1, ESR2, AR, NCOA1 and NCOR1 mRNA, in addition to significantly increased levels of CYP19A1 mRNA were demonstrated in tumoral tissue samples compared with adjacent healthy gastric tissue samples.

Summary
Symbol	NCOR1
Name	nuclear receptor corepressor 1
Aliases	N-CoR; hCIT529I10; hN-CoR; KIAA1047; MGC104216; PPP1R109; thyroid hormone- and retinoic acid receptor-associ ......
Location	17p12-p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

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Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.427	2.31e-19	51	38.6	10.4	Loss
BRCA	Breast invasive carcinoma	1075	0.43	1.43e-49	58	35.8	6.1	Loss
CESC	Cervical and endocervical cancers	292	0.433	8.32e-15	35.3	58.9	5.8	Loss
COAD	Colon adenocarcinoma	449	0.561	1.56e-38	55.7	41.4	2.9	Loss
ESCA	Esophageal carcinoma	183	0.499	6.19e-13	47.5	38.3	14.2	Loss
GBM	Glioblastoma multiforme	147	0.275	0.000762	16.3	77.6	6.1	Neutral
HNSC	Head and Neck squamous cell carcinoma	514	0.311	5.07e-13	20.8	65.4	13.8	Neutral
KIRC	Kidney renal clear cell carcinoma	525	0.416	1.97e-23	8.8	86.3	5	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	0.382	1.88e-11	4.9	36.1	59	Gain
LAML	Acute Myeloid Leukemia	166	0.512	1.7e-12	8.4	91.6	0	Neutral
LGG	Brain Lower Grade Glioma	513	0.169	0.000115	2.9	93.2	3.9	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.51	1.91e-25	52.5	42	5.5	Loss
LUAD	Lung adenocarcinoma	512	0.4	3.89e-21	48	39.6	12.3	Loss
LUSC	Lung squamous cell carcinoma	498	0.517	2.14e-35	61	28.3	10.6	Loss
OV	Ovarian serous cystadenocarcinoma	300	0.531	2.9e-23	86	10.3	3.7	Loss
PAAD	Pancreatic adenocarcinoma	177	0.518	1.6e-13	44.1	50.3	5.6	Loss
PCPG	Pheochromocytoma and Paraganglioma	162	0.49	3.58e-11	39.5	59.9	0.6	Loss
PRAD	Prostate adenocarcinoma	491	0.212	2.2e-06	17.3	80.4	2.2	Neutral
READ	Rectum adenocarcinoma	164	0.535	1.58e-13	68.3	29.9	1.8	Loss
SARC	Sarcoma	255	0.667	2.99e-34	16.5	45.9	37.6	Gain
SKCM	Skin Cutaneous Melanoma	367	0.53	6.15e-28	34.3	54.8	10.9	Loss
STAD	Stomach adenocarcinoma	413	0.542	5.73e-33	38.5	55.7	5.8	Loss
TGCT	Testicular Germ Cell Tumors	150	0.393	6.61e-07	24.7	46	29.3	Neutral
THCA	Thyroid carcinoma	497	0.134	0.00274	1.4	95.2	3.4	Neutral
THYM	Thymoma	119	0.111	0.228	11.8	85.7	2.5	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.439	1.13e-26	24.8	71.5	3.7	Neutral

Summary
Symbol	NCOR1
Name	nuclear receptor corepressor 1
Aliases	N-CoR; hCIT529I10; hN-CoR; KIAA1047; MGC104216; PPP1R109; thyroid hormone- and retinoic acid receptor-associ ......
Location	17p12-p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

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Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.123	0.0109	17	408	0	0.129	NS/NA
BRCA	Breast invasive carcinoma	-0.337	0	83	785	0.003	0.00779	NS/NA
CESC	Cervical and endocervical cancers	-0.25	9.24e-06	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.242	1.46e-05	19	297	0.003	0.71	NS/NA
ESCA	Esophageal carcinoma	-0.24	0.000794	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.144	0.252	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.295	2.84e-12	20	522	0.002	0.0508	NS/NA
KIRC	Kidney renal clear cell carcinoma	-0.039	0.474	24	319	0.003	1.97e-06	NS/NA
KIRP	Kidney renal papillary cell carcinoma	-0.287	5.43e-07	23	275	0.002	0.0628	NS/NA
LAML	Acute Myeloid Leukemia	-0.21	0.00601	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	-0.163	0.00016	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.342	1.23e-12	41	373	0.002	0.00245	NS/NA
LUAD	Lung adenocarcinoma	-0.117	0.0107	21	456	0.005	0.547	NS/NA
LUSC	Lung squamous cell carcinoma	-0.252	7.93e-07	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	-0.467	0.213	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.09	0.226	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.22	0.00252	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.292	8.14e-12	35	498	0.002	1.88e-08	NS/NA
READ	Rectum adenocarcinoma	-0.309	0.00174	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.374	5.11e-10	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.31	6.88e-12	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.203	8.09e-05	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.133	0.0976	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	0.001	0.978	50	509	-0.001	0.181	NS/NA
THYM	Thymoma	-0.026	0.773	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.264	8.48e-09	34	431	-0.002	0.156	NS/NA

Summary
Symbol	NCOR1
Name	nuclear receptor corepressor 1
Aliases	N-CoR; hCIT529I10; hN-CoR; KIAA1047; MGC104216; PPP1R109; thyroid hormone- and retinoic acid receptor-associ ......
Location	17p12-p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Level	Level Name
Adrenal gland	2	Medium
Appendix	2	Medium
Bone marrow	1	Low
Breast	0	Not detected
Bronchus	3	High
Caudate	2	Medium
Cerebellum	2	Medium
Cerebral cortex	2	Medium
Cervix, uterine	3	High
Colon	3	High
Duodenum	3	High
Endometrium	2	Medium
Epididymis	2	Medium
Esophagus	2	Medium
Fallopian tube	2	Medium
Gallbladder	2	Medium
Heart muscle	2	Medium
Hippocampus	2	Medium
Kidney	3	High
Liver	2	Medium
Lung	2	Medium
Lymph node	2	Medium
Nasopharynx	2	Medium
Oral mucosa	2	Medium
Ovary	0	Not detected
Pancreas	3	High
Parathyroid gland	2	Medium
Placenta	2	Medium
Prostate	2	Medium
Rectum	3	High
Salivary gland	2	Medium
Seminal vesicle	2	Medium
Skeletal muscle	2	Medium
Skin	2	Medium
Small intestine	3	High
Smooth muscle	2	Medium
Soft tissue	0	Not detected
Spleen	1	Low
Stomach	3	High
Testis	2	Medium
Thyroid gland	2	Medium
Tonsil	2	Medium
Urinary bladder	3	High
Vagina	2	Medium

Summary
Symbol	NCOR1
Name	nuclear receptor corepressor 1
Aliases	N-CoR; hCIT529I10; hN-CoR; KIAA1047; MGC104216; PPP1R109; thyroid hormone- and retinoic acid receptor-associ ......
Location	17p12-p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.188	NS	24476821
BRCA	Breast invasive carcinoma	521	5.25e-09	Significant	23000897
COAD	Colon adenocarcinoma	149	0.805	NS	22810696
GBM	Glioblastoma multiforme	157	0.00146	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	0.0592	NS	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.046	Significant	26536169
LGG	Brain Lower Grade Glioma	513	0.0143	Significant	26824661
LUAD	Lung adenocarcinoma	230	0.00115	Significant	25079552
LUSC	Lung squamous cell carcinoma	178	0.00186	Significant	22960745
OV	Ovarian serous cystadenocarcinoma	287	0.0469	Significant	21720365
PRAD	Prostate adenocarcinoma	333	0.693	NS	26544944
READ	Rectum adenocarcinoma	67	0.0907	NS	22810696
SKCM	Skin Cutaneous Melanoma	315	0.956	NS	26091043
STAD	Stomach adenocarcinoma	277	3.74e-05	Significant	25079317
THCA	Thyroid carcinoma	391	0.81	NS	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	3.59e-05	Significant	23636398

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	1.347	0.171	NS
BRCA	Breast invasive carcinoma	1079	1.515	0.0759	NS
CESC	Cervical and endocervical cancers	291	1.347	0.348	NS
COAD	Colon adenocarcinoma	439	1.012	0.968	NS
ESCA	Esophageal carcinoma	184	0.834	0.575	NS
GBM	Glioblastoma multiforme	158	0.884	0.65	NS
HNSC	Head and Neck squamous cell carcinoma	518	0.758	0.159	NS
KIRC	Kidney renal clear cell carcinoma	531	0.391	1.26e-05	Longer
KIRP	Kidney renal papillary cell carcinoma	287	0.679	0.362	NS
LAML	Acute Myeloid Leukemia	149	0.699	0.22	NS
LGG	Brain Lower Grade Glioma	511	1.049	0.847	NS
LIHC	Liver hepatocellular carcinoma	365	0.638	0.0793	NS
LUAD	Lung adenocarcinoma	502	1.098	0.648	NS
LUSC	Lung squamous cell carcinoma	494	1.338	0.13	NS
OV	Ovarian serous cystadenocarcinoma	303	1.13	0.568	NS
PAAD	Pancreatic adenocarcinoma	177	1.155	0.607	NS
PCPG	Pheochromocytoma and Paraganglioma	179	600536125.311	0.0817	NS
PRAD	Prostate adenocarcinoma	497	1.882	0.549	NS
READ	Rectum adenocarcinoma	159	0.353	0.0634	NS
SARC	Sarcoma	259	1.086	0.785	NS
SKCM	Skin Cutaneous Melanoma	459	1.021	0.917	NS
STAD	Stomach adenocarcinoma	388	0.644	0.0611	NS
TGCT	Testicular Germ Cell Tumors	134	0.95	0.971	NS
THCA	Thyroid carcinoma	500	1.299	0.774	NS
THYM	Thymoma	119	0.664	0.653	NS
UCEC	Uterine Corpus Endometrial Carcinoma	543	0.974	0.928	NS

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	-0.051	0.301	NS
BRCA	Breast invasive carcinoma	1071	0.017	0.568	NS
CESC	Cervical and endocervical cancers	167	0.069	0.373	NS
COAD	Colon adenocarcinoma	445	-0.078	0.1	NS
ESCA	Esophageal carcinoma	162	0.02	0.8	NS
HNSC	Head and Neck squamous cell carcinoma	448	-0.046	0.332	NS
KIRC	Kidney renal clear cell carcinoma	531	-0.115	0.00813	Lower
KIRP	Kidney renal papillary cell carcinoma	260	-0.14	0.0245	Lower
LIHC	Liver hepatocellular carcinoma	347	-0.002	0.976	NS
LUAD	Lung adenocarcinoma	507	0.046	0.301	NS
LUSC	Lung squamous cell carcinoma	497	-0.01	0.823	NS
OV	Ovarian serous cystadenocarcinoma	302	-0.046	0.421	NS
PAAD	Pancreatic adenocarcinoma	176	-0.039	0.608	NS
READ	Rectum adenocarcinoma	156	-0.004	0.964	NS
SKCM	Skin Cutaneous Melanoma	410	-0.01	0.833	NS
STAD	Stomach adenocarcinoma	392	0.02	0.697	NS
TGCT	Testicular Germ Cell Tumors	81	-0.026	0.82	NS
THCA	Thyroid carcinoma	499	-0.061	0.176	NS
UCEC	Uterine Corpus Endometrial Carcinoma	501	-0.086	0.0536	NS

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	-0.072	0.233	NS
HNSC	Head and Neck squamous cell carcinoma	498	0.015	0.745	NS
KIRC	Kidney renal clear cell carcinoma	525	-0.121	0.00565	Lower
LGG	Brain Lower Grade Glioma	514	0.05	0.259	NS
LIHC	Liver hepatocellular carcinoma	366	-0.058	0.265	NS
OV	Ovarian serous cystadenocarcinoma	296	0.036	0.542	NS
PAAD	Pancreatic adenocarcinoma	176	-0.088	0.247	NS
STAD	Stomach adenocarcinoma	406	0.055	0.266	NS
UCEC	Uterine Corpus Endometrial Carcinoma	534	-0.038	0.382	NS

Summary
Symbol	NCOR1
Name	nuclear receptor corepressor 1
Aliases	N-CoR; hCIT529I10; hN-CoR; KIAA1047; MGC104216; PPP1R109; thyroid hormone- and retinoic acid receptor-associ ......
Location	17p12-p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	NCOR1
Name	nuclear receptor corepressor 1
Aliases	N-CoR; hCIT529I10; hN-CoR; KIAA1047; MGC104216; PPP1R109; thyroid hormone- and retinoic acid receptor-associ ......
Location	17p12-p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for NCOR1.

Summary
Symbol	NCOR1
Name	nuclear receptor corepressor 1
Aliases	N-CoR; hCIT529I10; hN-CoR; KIAA1047; MGC104216; PPP1R109; thyroid hormone- and retinoic acid receptor-associ ......
Location	17p12-p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining

[ TOP ]

PMID	Cancer	Hierarchy	Gene	Relation to CR	Evidence
16195251	Prostate Carcinoma	partner	SAFB	Interaction	This interaction was direct, and was mediated in vitro and in vivo through the C-terminal region of SAFB1 (amino acids 600-915 and the N-terminal region of N-CoR (amino acids 1-373)).