CR2Cancer

Summary
Symbol	POGZ
Name	pogo transposable element derived with ZNF domain
Aliases	KIAA0461; ZNF635m; ZNF280E; zinc finger protein 280E; putative protein product of Nbla00003; MRD37; ZNF635; ......
Location	1q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

[ TOP ]

Domain

PF03184 DDE superfamily endonuclease
PF03221 Tc5 transposase DNA-binding domain

Function

Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms.

Classification

Class	Modification	Substrate	Product	PubMed
Histone modification read	Histone methylation	H3K9me3	#	20562864, 20850016

> Gene Ontology [ TOP ]
Biological Process	GO:0000070 mitotic sister chromatid segregation GO:0000819 sister chromatid segregation GO:0007059 chromosome segregation GO:0007062 sister chromatid cohesion GO:0007064 mitotic sister chromatid cohesion GO:0007067 mitotic nuclear division GO:0034508 centromere complex assembly GO:0051382 kinetochore assembly GO:0051383 kinetochore organization GO:0065004 protein-DNA complex assembly GO:0071824 protein-DNA complex subunit organization GO:0098813 nuclear chromosome segregation
Molecular Function	-
Cellular Component	GO:0000785 chromatin GO:0000790 nuclear chromatin GO:0044454 nuclear chromosome part

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	-

Summary
Symbol	POGZ
Name	pogo transposable element derived with ZNF domain
Aliases	KIAA0461; ZNF635m; ZNF280E; zinc finger protein 280E; putative protein product of Nbla00003; MRD37; ZNF635; ......
Location	1q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM72241	c.575G>A	p.G192D	Substitution - Missense	Ovary
COSM895813	c.2361C>A	p.A787A	Substitution - coding silent	Endometrium
COSM895811	c.2425T>C	p.S809P	Substitution - Missense	Endometrium
COSM1600795	c.1475C>T	p.T492I	Substitution - Missense	Liver
COSM895825	c.1793G>A	p.R598H	Substitution - Missense	Endometrium
COSM3473681	c.1501A>C	p.K501Q	Substitution - Missense	Skin
COSM3984216	c.4124C>T	p.P1375L	Substitution - Missense	Kidney
COSM5516166	c.226delG	p.A76fs*14	Deletion - Frameshift	Biliary_tract
COSM895852	c.237C>T	p.S79S	Substitution - coding silent	Endometrium
COSM1720077	c.404_405CC>AT	p.A135D	Substitution - Missense	Skin
COSM1221415	c.1120C>T	p.R374W	Substitution - Missense	Large_intestine
COSM251269	c.1261_1263delGCA	p.A421delA	Deletion - In frame	Liver
COSM895801	c.4185G>T	p.E1395D	Substitution - Missense	Endometrium
COSM5556810	c.3169A>G	p.I1057V	Substitution - Missense	Prostate
COSM1747738	c.1582G>A	p.G528S	Substitution - Missense	Urinary_tract
COSM1720077	c.404_405CC>AT	p.A135D	Substitution - Missense	Skin
COSM4855380	c.4177G>C	p.E1393Q	Substitution - Missense	Cervix
COSM2183633	c.1337C>T	p.P446L	Substitution - Missense	Large_intestine
COSM3473669	c.4098T>C	p.S1366S	Substitution - coding silent	Skin
COSM3473677	c.2172T>A	p.P724P	Substitution - coding silent	Skin
COSM4414646	c.2079C>T	p.S693S	Substitution - coding silent	Kidney
COSM1626429	c.1744A>G	p.T582A	Substitution - Missense	Liver
COSM1639500	c.3192delG	p.F1065fs*17	Deletion - Frameshift	Stomach
COSM3700485	c.1000C>G	p.P334A	Substitution - Missense	Liver
COSM675458	c.2965A>T	p.T989S	Substitution - Missense	Lung
COSM895855	c.13G>A	p.D5N	Substitution - Missense	Endometrium
COSM4615445	c.3351delA	p.L1117fs*5	Deletion - Frameshift	Large_intestine
COSM267218	c.2350C>T	p.R784*	Substitution - Nonsense	Large_intestine
COSM4716362	c.859+2T>C	p.?	Unknown	Large_intestine
COSM4022245	c.1688A>C	p.K563T	Substitution - Missense	Stomach
COSM2183627	c.1505G>A	p.R502K	Substitution - Missense	Large_intestine
COSM3360332	c.3958C>A	p.Q1320K	Substitution - Missense	Kidney
COSM136163	c.3259C>T	p.R1087*	Substitution - Nonsense	Skin
COSM1221417	c.3116G>A	p.R1039H	Substitution - Missense	Large_intestine
COSM4221138	c.1957C>T	p.R653W	Substitution - Missense	Large_intestine
COSM5651074	c.1704G>A	p.A568A	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM1319996	c.455C>G	p.T152R	Substitution - Missense	Ovary
COSM76005	c.703C>G	p.L235V	Substitution - Missense	Ovary
COSM5341549	c.4097C>G	p.S1366C	Substitution - Missense	Large_intestine
COSM3704973	c.283+8G>A	p.?	Unknown	Liver
COSM3801827	c.3225C>G	p.F1075L	Substitution - Missense	Breast
COSM4716358	c.1427G>A	p.R476Q	Substitution - Missense	Large_intestine
COSM3418039	c.934G>A	p.E312K	Substitution - Missense	Large_intestine
COSM1333984	c.3459G>A	p.G1153G	Substitution - coding silent	Large_intestine
COSM5453917	c.765T>C	p.T255T	Substitution - coding silent	Large_intestine
COSM4022233	c.2966C>T	p.T989I	Substitution - Missense	Stomach
COSM1472603	c.3618G>C	p.E1206D	Substitution - Missense	Breast
COSM1667934	c.3712G>T	p.E1238*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM1333996	c.1093C>T	p.P365S	Substitution - Missense	Large_intestine
COSM3704971	c.3135A>G	p.V1045V	Substitution - coding silent	Liver
COSM3704971	c.3135A>G	p.V1045V	Substitution - coding silent	Liver
COSM4566535	c.4056_4057CC>TT	p.(=)	Unknown	Skin
COSM5887614	c.1276C>T	p.P426S	Substitution - Missense	Upper_aerodigestive_tract
COSM4507156	c.738C>T	p.S246S	Substitution - coding silent	Skin
COSM2183588	c.2390G>T	p.R797L	Substitution - Missense	Large_intestine
COSM5031968	c.1234G>T	p.D412Y	Substitution - Missense	Pancreas
COSM5943210	c.2273_2274delTC	p.F758fs*1	Deletion - Frameshift	Skin
COSM4716360	c.1177delC	p.H393fs*77	Deletion - Frameshift	Large_intestine
COSM4762608	c.3532G>T	p.G1178W	Substitution - Missense	Stomach
COSM895851	c.279C>T	p.N93N	Substitution - coding silent	Endometrium
COSM246697	c.1667A>G	p.Y556C	Substitution - Missense	Liver
COSM1726060	c.2776G>C	p.A926P	Substitution - Missense	Liver
COSM5903359	c.2138A>G	p.Q713R	Substitution - Missense	Skin
COSM895833	c.1650A>G	p.E550E	Substitution - coding silent	Endometrium
COSM4986281	c.4086A>C	p.E1362D	Substitution - Missense	Soft_tissue
COSM5606937	c.1417T>A	p.Y473N	Substitution - Missense	Skin
COSM4475224	c.1971C>T	p.L657L	Substitution - coding silent	Skin
COSM4777696	c.510_511insG	p.I172fs*12	Insertion - Frameshift	Prostate
COSM4778409	c.2313A>G	p.V771V	Substitution - coding silent	Liver
COSM4958394	c.2763C>T	p.P921P	Substitution - coding silent	Liver
COSM1688528	c.1393C>T	p.L465F	Substitution - Missense	Skin
COSM1688530	c.343C>T	p.P115S	Substitution - Missense	Skin
COSM5927175	c.4054T>C	p.S1352P	Substitution - Missense	Skin
COSM4415660	c.1524-10T>G	p.?	Unknown	Haematopoietic_and_lymphoid_tissue
COSM1333986	c.3046delG	p.E1016fs*3	Deletion - Frameshift	Large_intestine
COSM383722	c.1931G>C	p.R644T	Substitution - Missense	Lung
COSM1221421	c.2465T>G	p.F822C	Substitution - Missense	Large_intestine
COSM3737119	c.2319_2320delCT	p.L775fs*4	Deletion - Frameshift	Soft_tissue
COSM895817	c.2080C>T	p.R694*	Substitution - Nonsense	Endometrium
COSM5627026	c.2571-2A>T	p.?	Unknown	Oesophagus
COSM895847	c.1121G>A	p.R374Q	Substitution - Missense	Endometrium
COSM4441858	c.2221G>T	p.A741S	Substitution - Missense	Large_intestine
COSM4022211	c.3662G>A	p.R1221H	Substitution - Missense	Stomach
COSM246697	c.1667A>G	p.Y556C	Substitution - Missense	Prostate
COSM2183651	c.850C>T	p.P284S	Substitution - Missense	Skin
COSM1333994	c.2130C>T	p.S710S	Substitution - coding silent	Large_intestine
COSM423824	c.3926T>C	p.L1309P	Substitution - Missense	Breast
COSM1221419	c.2935C>T	p.R979*	Substitution - Nonsense	Large_intestine
COSM4022237	c.2793G>A	p.P931P	Substitution - coding silent	Stomach
COSM5704922	c.4207G>A	p.A1403T	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM400834	c.2093G>T	p.R698L	Substitution - Missense	Lung
COSM4142623	c.1274C>A	p.S425Y	Substitution - Missense	Thyroid
COSM4745684	c.2650G>A	p.A884T	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM462935	c.3460G>A	p.E1154K	Substitution - Missense	Kidney
COSM5685827	c.3609G>A	p.E1203E	Substitution - coding silent	Soft_tissue
COSM4221140	c.1229C>T	p.S410F	Substitution - Missense	Skin
COSM5567181	c.3071G>A	p.S1024N	Substitution - Missense	Prostate
COSM257768	c.1828C>T	p.R610W	Substitution - Missense	Large_intestine
COSM5606937	c.1417T>A	p.Y473N	Substitution - Missense	Skin
COSM895815	c.2235-1G>T	p.?	Unknown	Endometrium
COSM163601	c.1234G>C	p.D412H	Substitution - Missense	Breast
COSM5795821	c.1150T>G	p.F384V	Substitution - Missense	Breast
COSM4022219	c.3236A>G	p.H1079R	Substitution - Missense	Stomach
COSM3801829	c.2116G>A	p.D706N	Substitution - Missense	Breast
COSM3704973	c.283+8G>A	p.?	Unknown	Liver
COSM1626427	c.1927-1G>T	p.?	Unknown	Liver
COSM5808671	c.3642G>C	p.Q1214H	Substitution - Missense	Liver
COSM5985727	c.199A>G	p.T67A	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM895853	c.222_223insAGC	p.S74_G75insS	Insertion - In frame	Endometrium
COSM4022239	c.2355T>G	p.A785A	Substitution - coding silent	Stomach
COSM2183627	c.1505G>A	p.R502K	Substitution - Missense	Large_intestine
COSM1733360	c.1271delC	p.P424fs*46	Deletion - Frameshift	Pancreas
COSM423826	c.3377A>G	p.D1126G	Substitution - Missense	Breast
COSM1688526	c.1462C>T	p.P488S	Substitution - Missense	Skin
COSM4022213	c.3285G>T	p.K1095N	Substitution - Missense	Stomach
COSM5452783	c.860-4G>A	p.?	Unknown	Large_intestine
COSM4566503	c.3965_3966CC>TT	p.S1322F	Substitution - Missense	Skin
COSM4022251	c.574G>T	p.G192C	Substitution - Missense	Stomach
COSM895854	c.147C>A	p.V49V	Substitution - coding silent	Endometrium
COSM2183627	c.1505G>A	p.R502K	Substitution - Missense	Large_intestine
COSM3740652	c.255T>C	p.T85T	Substitution - coding silent	Liver
COSM1582196	c.311G>C	p.G104A	Substitution - Missense	Stomach
COSM1600795	c.1475C>T	p.T492I	Substitution - Missense	Liver
COSM895805	c.3328C>T	p.R1110W	Substitution - Missense	Endometrium
COSM2183532	c.3837delA	p.K1279fs*31	Deletion - Frameshift	Stomach
COSM4022221	c.3223T>G	p.F1075V	Substitution - Missense	Stomach
COSM895829	c.1692C>T	p.I564I	Substitution - coding silent	Endometrium
COSM2183627	c.1505G>A	p.R502K	Substitution - Missense	Large_intestine
COSM5794016	c.3518T>A	p.L1173Q	Substitution - Missense	Breast
COSM4878046	c.721G>A	p.V241I	Substitution - Missense	Prostate
COSM5606937	c.1417T>A	p.Y473N	Substitution - Missense	Skin
COSM3473671	c.4014A>T	p.S1338S	Substitution - coding silent	Skin
COSM1600797	c.1414T>G	p.F472V	Substitution - Missense	Liver
COSM895815	c.2235-1G>T	p.?	Unknown	Large_intestine
COSM895803	c.3997G>A	p.D1333N	Substitution - Missense	Endometrium
COSM4891235	c.3854G>A	p.R1285Q	Substitution - Missense	Upper_aerodigestive_tract
COSM1333990	c.3022C>T	p.R1008*	Substitution - Nonsense	Large_intestine
COSM372093	c.3257_3258GG>TT	p.R1086>?	Complex	Lung
COSM895835	c.1522C>T	p.R508*	Substitution - Nonsense	Endometrium
COSM1667937	c.3026G>A	p.R1009H	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM462937	c.2149C>A	p.P717T	Substitution - Missense	Kidney
COSM1221415	c.1120C>T	p.R374W	Substitution - Missense	Stomach
COSM241209	c.65G>A	p.S22N	Substitution - Missense	Prostate
COSM4489476	c.3480C>T	p.V1160V	Substitution - coding silent	Skin
COSM3473687	c.723C>T	p.V241V	Substitution - coding silent	Skin
COSM4022209	c.3692A>G	p.H1231R	Substitution - Missense	Stomach
COSM2183614	c.1969C>T	p.L657F	Substitution - Missense	Cervix
COSM4022249	c.656C>A	p.P219H	Substitution - Missense	Stomach
COSM4617131	c.2248C>T	p.R750W	Substitution - Missense	Large_intestine
COSM3473673	c.3112C>T	p.Q1038*	Substitution - Nonsense	Skin
COSM895819	c.2021G>A	p.R674H	Substitution - Missense	Endometrium
COSM1688524	c.1648G>A	p.E550K	Substitution - Missense	Skin
COSM5377600	c.2101C>A	p.P701T	Substitution - Missense	Skin
COSM6006606	c.2125C>T	p.P709S	Substitution - Missense	Prostate
COSM2183647	c.917G>A	p.R306Q	Substitution - Missense	Large_intestine
COSM222555	c.517G>A	p.V173M	Substitution - Missense	Skin
COSM3369277	c.3781A>T	p.I1261F	Substitution - Missense	Thyroid
COSM5631649	c.1875G>A	p.L625L	Substitution - coding silent	Oesophagus
COSM4022241	c.2330G>A	p.R777H	Substitution - Missense	Stomach
COSM76004	c.3499G>T	p.G1167C	Substitution - Missense	Ovary
COSM5618590	c.2953C>G	p.L985V	Substitution - Missense	Breast
COSM5716913	c.3153C>T	p.F1051F	Substitution - coding silent	Skin
COSM5377596	c.3458G>A	p.G1153E	Substitution - Missense	Skin
COSM4617129	c.2457A>G	p.S819S	Substitution - coding silent	Large_intestine
COSM5613754	c.1558G>C	p.D520H	Substitution - Missense	Lung
COSM288897	c.1700G>A	p.W567*	Substitution - Nonsense	Large_intestine
COSM3473679	c.2045T>G	p.L682W	Substitution - Missense	Skin
COSM4958394	c.2763C>T	p.P921P	Substitution - coding silent	Liver
COSM4932417	c.332A>G	p.Q111R	Substitution - Missense	Liver
COSM5052554	c.3961C>T	p.R1321C	Substitution - Missense	Stomach
COSM3376719	c.3302C>T	p.A1101V	Substitution - Missense	Pancreas
COSM1168639	c.342C>T	p.A114A	Substitution - coding silent	Pancreas
COSM381183	c.4045C>A	p.L1349I	Substitution - Missense	Lung
COSM895827	c.1766C>A	p.P589H	Substitution - Missense	Endometrium
COSM895823	c.1817A>G	p.D606G	Substitution - Missense	Endometrium
COSM4973607	c.2136G>T	p.L712F	Substitution - Missense	Oesophagus
COSM895845	c.1140T>C	p.C380C	Substitution - coding silent	Endometrium
COSM895847	c.1121G>A	p.R374Q	Substitution - Missense	Stomach
COSM251269	c.1261_1263delGCA	p.A421delA	Deletion - In frame	Liver
COSM5800322	c.1609C>T	p.R537C	Substitution - Missense	Breast
COSM5461991	c.3514A>G	p.T1172A	Substitution - Missense	Large_intestine
COSM675454	c.2546-4A>G	p.?	Unknown	Liver
COSM3984220	c.1676C>A	p.T559N	Substitution - Missense	Kidney
COSM4382632	c.2602C>T	p.R868W	Substitution - Missense	Large_intestine
COSM5682693	c.3607G>A	p.E1203K	Substitution - Missense	Soft_tissue
COSM4022215	c.3274A>G	p.T1092A	Substitution - Missense	Stomach
COSM4022243	c.1889A>C	p.N630T	Substitution - Missense	Stomach
COSM5377602	c.2075C>T	p.A692V	Substitution - Missense	Skin
COSM4438426	c.569-4A>C	p.?	Unknown	Oesophagus
COSM4022223	c.3201C>A	p.I1067I	Substitution - coding silent	Stomach
COSM1333982	c.3695G>A	p.R1232H	Substitution - Missense	Breast
COSM1333988	c.3042G>T	p.Q1014H	Substitution - Missense	Large_intestine
COSM2183534	c.3789A>G	p.P1263P	Substitution - coding silent	Large_intestine
COSM895841	c.1368C>T	p.N456N	Substitution - coding silent	Endometrium
COSM462939	c.1057G>A	p.G353R	Substitution - Missense	Kidney
COSM3862674	c.872C>T	p.P291L	Substitution - Missense	Skin
COSM5880739	c.2924T>G	p.V975G	Substitution - Missense	Soft_tissue
COSM5606937	c.1417T>A	p.Y473N	Substitution - Missense	Skin
COSM5716913	c.3153C>T	p.F1051F	Substitution - coding silent	Skin
COSM4022247	c.1374C>T	p.G458G	Substitution - coding silent	Stomach
COSM1472605	c.2423A>G	p.N808S	Substitution - Missense	Breast
COSM4022253	c.158T>A	p.V53E	Substitution - Missense	Stomach
COSM1221423	c.3530G>A	p.R1177K	Substitution - Missense	Large_intestine
COSM4022235	c.2832T>A	p.D944E	Substitution - Missense	Stomach
COSM2183554	c.3115C>T	p.R1039C	Substitution - Missense	Prostate
COSM3984218	c.2755C>T	p.P919S	Substitution - Missense	Kidney
COSM2183528	c.4056C>T	p.S1352S	Substitution - coding silent	Skin
COSM1747736	c.3215C>A	p.A1072D	Substitution - Missense	Urinary_tract
COSM3862672	c.1070C>T	p.S357L	Substitution - Missense	Skin
COSM895807	c.2725C>T	p.P909S	Substitution - Missense	Endometrium
COSM4936551	c.260T>G	p.V87G	Substitution - Missense	Liver
COSM5042715	c.3962G>A	p.R1321H	Substitution - Missense	Liver
COSM895843	c.1198G>T	p.E400*	Substitution - Nonsense	Endometrium
COSM5742758	c.829C>T	p.Q277*	Substitution - Nonsense	Small_intestine
COSM5950612	c.3956T>C	p.V1319A	Substitution - Missense	Prostate
COSM5477612	c.6G>A	p.A2A	Substitution - coding silent	Large_intestine
COSM4716352	c.4182C>T	p.T1394T	Substitution - coding silent	Large_intestine
COSM4716356	c.2081G>A	p.R694Q	Substitution - Missense	Large_intestine
COSM3473685	c.981C>T	p.I327I	Substitution - coding silent	Skin
COSM423828	c.367C>G	p.Q123E	Substitution - Missense	Breast
COSM895839	c.1426C>T	p.R476W	Substitution - Missense	Endometrium
COSM1221414	c.211G>A	p.V71I	Substitution - Missense	Large_intestine
COSM1600793	c.1945T>A	p.C649S	Substitution - Missense	Liver
COSM1168639	c.342C>T	p.A114A	Substitution - coding silent	Pancreas
COSM3849266	c.542C>T	p.T181M	Substitution - Missense	Pancreas
COSM328986	c.1960C>A	p.L654M	Substitution - Missense	Liver
COSM3473683	c.1034C>T	p.A345V	Substitution - Missense	Skin
COSM1744141	c.2043C>T	p.G681G	Substitution - coding silent	Biliary_tract
COSM4949832	c.1463C>G	p.P488R	Substitution - Missense	Liver
COSM4716354	c.3377A>C	p.D1126A	Substitution - Missense	Large_intestine
COSM4850108	c.367C>T	p.Q123*	Substitution - Nonsense	Cervix
COSM4022227	c.3117C>T	p.R1039R	Substitution - coding silent	Stomach
COSM224172	c.338C>T	p.P113L	Substitution - Missense	Skin
COSM1295051	c.3005G>A	p.R1002H	Substitution - Missense	Urinary_tract
COSM4022225	c.3191G>A	p.G1064E	Substitution - Missense	Stomach
COSM4496047	c.466C>T	p.P156S	Substitution - Missense	Skin
COSM171460	c.3220C>T	p.R1074C	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3788686	c.2925G>A	p.V975V	Substitution - coding silent	Urinary_tract
COSM5716913	c.3153C>T	p.F1051F	Substitution - coding silent	Skin
COSM383720	c.2772G>C	p.P924P	Substitution - coding silent	Lung
COSM895835	c.1522C>T	p.R508*	Substitution - Nonsense	Endometrium
COSM895831	c.1654G>A	p.V552I	Substitution - Missense	Endometrium
COSM1333992	c.2203C>T	p.R735C	Substitution - Missense	Large_intestine
COSM3376723	c.478G>A	p.V160I	Substitution - Missense	Pancreas
COSM5606937	c.1417T>A	p.Y473N	Substitution - Missense	Skin
COSM4022231	c.3023G>A	p.R1008Q	Substitution - Missense	Stomach
COSM4022229	c.3099G>A	p.E1033E	Substitution - coding silent	Stomach
COSM273788	c.3637_3638delTG	p.W1213fs*31	Deletion - Frameshift	Large_intestine
COSM4822333	c.2321C>G	p.S774C	Substitution - Missense	Cervix
COSM4949832	c.1463C>G	p.P488R	Substitution - Missense	Liver
COSM2183548	c.3483A>G	p.L1161L	Substitution - coding silent	Large_intestine
COSM895821	c.1953A>G	p.K651K	Substitution - coding silent	Endometrium
COSM4469901	c.1626C>T	p.P542P	Substitution - coding silent	Skin
COSM5607574	c.968C>T	p.T323I	Substitution - Missense	Skin
COSM1295051	c.3005G>A	p.R1002H	Substitution - Missense	Large_intestine
COSM414073	c.2724C>T	p.L908L	Substitution - coding silent	Urinary_tract
COSM1747736	c.3215C>A	p.A1072D	Substitution - Missense	Urinary_tract
COSM3376717	c.3653C>G	p.A1218G	Substitution - Missense	Pancreas
COSM4022217	c.3257G>A	p.R1086Q	Substitution - Missense	Stomach
COSM1600797	c.1414T>G	p.F472V	Substitution - Missense	Liver
COSM1333982	c.3695G>A	p.R1232H	Substitution - Missense	Large_intestine
COSM1688524	c.1648G>A	p.E550K	Substitution - Missense	Skin
COSM404377	c.1955G>A	p.C652Y	Substitution - Missense	Lung
COSM895837	c.1483C>T	p.R495*	Substitution - Nonsense	Endometrium
COSM4022247	c.1374C>T	p.G458G	Substitution - coding silent	Stomach
COSM5377604	c.337C>T	p.P113S	Substitution - Missense	Skin
COSM5792612	c.1926+6A>G	p.?	Unknown	Breast
COSM895849	c.952G>A	p.A318T	Substitution - Missense	Endometrium
COSM5978099	c.2194C>T	p.P732S	Substitution - Missense	Upper_aerodigestive_tract
COSM1747738	c.1582G>A	p.G528S	Substitution - Missense	Urinary_tract
COSM895809	c.2426C>A	p.S809Y	Substitution - Missense	Endometrium
COSM171460	c.3220C>T	p.R1074C	Substitution - Missense	Large_intestine
COSM5922084	c.104C>T	p.S35L	Substitution - Missense	Skin
COSM3473675	c.2990G>T	p.R997L	Substitution - Missense	Skin
COSM1600793	c.1945T>A	p.C649S	Substitution - Missense	Liver
COSM3716423	c.2311G>T	p.V771L	Substitution - Missense	Prostate
COSM3976124	c.1570G>T	p.G524C	Substitution - Missense	Lung
COSM5517574	c.1990G>C	p.E664Q	Substitution - Missense	Biliary_tract
COSM4936667	c.98A>G	p.Y33C	Substitution - Missense	Liver
COSM5660716	c.3840G>A	p.W1280*	Substitution - Nonsense	Soft_tissue
COSM3418037	c.3319T>G	p.F1107V	Substitution - Missense	Large_intestine
COSM5377598	c.2666C>T	p.S889F	Substitution - Missense	Skin
COSM3376721	c.1367A>G	p.N456S	Substitution - Missense	Pancreas

> Text Mining based Variations [ TOP ]
There is no record for POGZ.

Summary
Symbol	POGZ
Name	pogo transposable element derived with ZNF domain
Aliases	KIAA0461; ZNF635m; ZNF280E; zinc finger protein 280E; putative protein product of Nbla00003; MRD37; ZNF635; ......
Location	1q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

[ TOP ]

Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant
Q7Z3K3	363	S	Phosphoserine	-	No	None detected
Q7Z3K3	425	S	Phosphoserine	-	No	None detected
Q7Z3K3	439	T	Phosphothreonine	-	No	None detected
Q7Z3K3	445	S	Phosphoserine	-	No	None detected
Q7Z3K3	463	T	Phosphothreonine	-	No	None detected
Q7Z3K3	856	S	Phosphoserine	-	No	None detected
Q7Z3K3	1338	S	Phosphoserine	-	No	None detected
Q7Z3K3	1364	S	Phosphoserine	-	No	None detected
Q7Z3K3	1367	S	Phosphoserine	-	No	None detected
Q7Z3K3	1368	T	Phosphothreonine	-	No	None detected
Q7Z3K3	1392	S	Phosphoserine	-	No	None detected

Summary
Symbol	POGZ
Name	pogo transposable element derived with ZNF domain
Aliases	KIAA0461; ZNF635m; ZNF280E; zinc finger protein 280E; putative protein product of Nbla00003; MRD37; ZNF635; ......
Location	1q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	6.452	6.25	0.065	0.749	NS
BRCA	Breast invasive carcinoma	112	1100	6.887	7.104	0.281	6.81e-07	NS
CESC	Cervical and endocervical cancers	3	306	6.671	6.355	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	5.969	5.773	-0.171	0.0359	NS
ESCA	Esophageal carcinoma	11	185	6.89	6.641	-0.183	0.359	NS
GBM	Glioblastoma multiforme	5	166	6.821	6.407	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	5.534	5.58	0.065	0.484	NS
KIRC	Kidney renal clear cell carcinoma	72	534	6.315	6.526	0.219	0.000263	NS
KIRP	Kidney renal papillary cell carcinoma	32	291	6.317	6.208	-0.013	0.929	NS
LAML	Acute Myeloid Leukemia	0	173	NA	7.587	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	6.924	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	4.883	5.578	0.726	2.44e-13	Over
LUAD	Lung adenocarcinoma	59	517	6.414	6.607	0.286	0.000874	NS
LUSC	Lung squamous cell carcinoma	51	501	6.242	6.433	0.175	0.0422	NS
OV	Ovarian serous cystadenocarcinoma	0	307	NA	6.963	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	6.314	6.387	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	6.333	6.505	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	6.307	6.462	0.177	0.00579	NS
READ	Rectum adenocarcinoma	10	167	5.919	5.809	-0.07	0.752	NS
SARC	Sarcoma	2	263	5.86	6.318	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	6.547	6.684	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	6.249	6.51	0.26	0.00519	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	7.209	NA	NA	NA
THCA	Thyroid carcinoma	59	509	6.954	6.796	-0.127	0.0314	NS
THYM	Thymoma	2	120	7.02	6.814	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	6.917	6.725	-0.213	0.0539	NS

> Cancer Cell Line Encyclopedia (CCLE)

[ TOP ]

Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	10.8
Autonomic ganglia	CHP212	9.8
Autonomic ganglia	IMR32	10.4
Autonomic ganglia	KELLY	9.9
Autonomic ganglia	KPNRTBM1	10.1
Autonomic ganglia	KPNSI9S	9.6
Autonomic ganglia	KPNYN	9.9
Autonomic ganglia	MHHNB11	10.4
Autonomic ganglia	NB1	10.5
Autonomic ganglia	NH6	9.9
Autonomic ganglia	SHSY5Y	10.4
Autonomic ganglia	SIMA	10
Autonomic ganglia	SKNAS	9.8
Autonomic ganglia	SKNBE2	10.3
Autonomic ganglia	SKNDZ	9.9
Autonomic ganglia	SKNFI	9.7
Autonomic ganglia	SKNSH	9.2
Biliary tract	HUCCT1	8.9
Biliary tract	HUH28	9
Biliary tract	SNU1079	9.6
Biliary tract	SNU1196	9.1
Biliary tract	SNU245	9.1
Biliary tract	SNU308	9.2
Biliary tract	SNU478	8.6
Bone	143B	9.5
Bone	A673	9.5
Bone	CADOES1	10
Bone	CAL78	8.5
Bone	G292CLONEA141B1	8.7
Bone	HOS	10.5
Bone	HS706T	8.6
Bone	HS737T	8.1
Bone	HS819T	8.1
Bone	HS821T	8.5
Bone	HS822T	8.2
Bone	HS863T	8.3
Bone	HS870T	7.9
Bone	HS888T	8.5
Bone	MG63	8.6
Bone	MHHES1	10.5
Bone	OUMS27	8.5
Bone	RDES	10.5
Bone	SJSA1	9.2
Bone	SKES1	10.2
Bone	SKNMC	9.7
Bone	SW1353	8.7
Bone	T173	8.3
Bone	TC71	9.1
Bone	U2OS	9.4
Breast	AU565	9
Breast	BT20	9
Breast	BT474	8.5
Breast	BT483	10.7
Breast	BT549	8.6
Breast	CAL120	8.7
Breast	CAL148	10.7
Breast	CAL51	9.5
Breast	CAL851	8.4
Breast	CAMA1	9.8
Breast	DU4475	10.1
Breast	EFM192A	9.1
Breast	EFM19	9.6
Breast	EVSAT	8.2
Breast	HCC1143	9
Breast	HCC1187	10.6
Breast	HCC1395	8.9
Breast	HCC1419	8.6
Breast	HCC1428	9.6
Breast	HCC1500	9.6
Breast	HCC1569	9.1
Breast	HCC1599	9.9
Breast	HCC1806	9.1
Breast	HCC1937	7.1
Breast	HCC1954	8.9
Breast	HCC202	9.3
Breast	HCC2157	8.4
Breast	HCC2218	9.7
Breast	HCC38	8.6
Breast	HCC70	8.1
Breast	HDQP1	9.5
Breast	HMC18	9
Breast	HS274T	8.3
Breast	HS281T	8.3
Breast	HS343T	8.3
Breast	HS578T	8.3
Breast	HS606T	8.5
Breast	HS739T	8.6
Breast	HS742T	8.5
Breast	JIMT1	8.4
Breast	KPL1	9.8
Breast	MCF7	9.6
Breast	MDAMB134VI	9.9
Breast	MDAMB157	9.1
Breast	MDAMB175VII	9.2
Breast	MDAMB231	8.5
Breast	MDAMB361	8.7
Breast	MDAMB415	8.5
Breast	MDAMB436	9.4
Breast	MDAMB453	9.5
Breast	MDAMB468	8.6
Breast	SKBR3	8.9
Breast	T47D	9.4
Breast	UACC812	11
Breast	UACC893	7.6
Breast	YMB1	9.8
Breast	ZR751	9.5
Breast	ZR7530	10.1
Central nervous system	1321N1	8.5
Central nervous system	42MGBA	8.2
Central nervous system	8MGBA	8.3
Central nervous system	A172	9.7
Central nervous system	AM38	8.5
Central nervous system	BECKER	8.8
Central nervous system	CAS1	8.8
Central nervous system	CCFSTTG1	8.5
Central nervous system	D283MED	10.3
Central nervous system	D341MED	10.3
Central nervous system	DAOY	9
Central nervous system	DBTRG05MG	8
Central nervous system	DKMG	9
Central nervous system	GAMG	7.8
Central nervous system	GB1	9.2
Central nervous system	GI1	9.3
Central nervous system	GMS10	8.9
Central nervous system	GOS3	9.1
Central nervous system	H4	8.9
Central nervous system	HS683	8.4
Central nervous system	KALS1	9
Central nervous system	KG1C	8.2
Central nervous system	KNS42	9.7
Central nervous system	KNS60	8.8
Central nervous system	KNS81	8.8
Central nervous system	KS1	8.6
Central nervous system	LN18	8.4
Central nervous system	LN229	9.4
Central nervous system	M059K	8.5
Central nervous system	MOGGCCM	8.7
Central nervous system	MOGGUVW	8.8
Central nervous system	NMCG1	8.2
Central nervous system	ONS76	9
Central nervous system	SF126	7.3
Central nervous system	SF295	8.2
Central nervous system	SNB19	8.8
Central nervous system	SNU1105	8.9
Central nervous system	SNU201	8.9
Central nervous system	SNU466	8.7
Central nervous system	SNU489	8.7
Central nervous system	SNU626	9.2
Central nervous system	SNU738	8.9
Central nervous system	SW1088	8.1
Central nervous system	SW1783	8.1
Central nervous system	T98G	8.7
Central nervous system	TM31	9.5
Central nervous system	U118MG	8.4
Central nervous system	U138MG	8.5
Central nervous system	U251MG	8.7
Central nervous system	U87MG	8.5
Central nervous system	YH13	9.3
Central nervous system	YKG1	9.4
Endometrium	AN3CA	9.2
Endometrium	COLO684	10.8
Endometrium	EFE184	8.9
Endometrium	EN	9.7
Endometrium	ESS1	8.8
Endometrium	HEC108	8.9
Endometrium	HEC151	8.1
Endometrium	HEC1A	8.7
Endometrium	HEC1B	9.4
Endometrium	HEC251	8.6
Endometrium	HEC265	8.7
Endometrium	HEC50B	8.7
Endometrium	HEC59	8.2
Endometrium	HEC6	8.7
Endometrium	ISHIKAWAHERAKLIO02ER	8.7
Endometrium	JHUEM1	8.7
Endometrium	JHUEM2	9.4
Endometrium	JHUEM3	9.1
Endometrium	KLE	8.6
Endometrium	MFE280	10.4
Endometrium	MFE296	8.9
Endometrium	MFE319	8.1
Endometrium	RL952	8.8
Endometrium	SNGM	9.3
Endometrium	SNU1077	9.6
Endometrium	SNU685	9.6
Endometrium	TEN	8.5
Haematopoietic and lymphoid	697	10
Haematopoietic and lymphoid	A3KAW	9.2
Haematopoietic and lymphoid	A4FUK	9.1
Haematopoietic and lymphoid	ALLSIL	10
Haematopoietic and lymphoid	AML193	9.1
Haematopoietic and lymphoid	AMO1	10.3
Haematopoietic and lymphoid	BCP1	9.1
Haematopoietic and lymphoid	BDCM	8.8
Haematopoietic and lymphoid	BL41	10.3
Haematopoietic and lymphoid	BL70	10.2
Haematopoietic and lymphoid	BV173	10
Haematopoietic and lymphoid	CA46	10.5
Haematopoietic and lymphoid	CI1	8.8
Haematopoietic and lymphoid	CMK115	8.9
Haematopoietic and lymphoid	CMK86	9.4
Haematopoietic and lymphoid	CMK	9.4
Haematopoietic and lymphoid	CMLT1	9.9
Haematopoietic and lymphoid	COLO775	9.5
Haematopoietic and lymphoid	DAUDI	10
Haematopoietic and lymphoid	DB	9.5
Haematopoietic and lymphoid	DEL	10.4
Haematopoietic and lymphoid	DND41	10.3
Haematopoietic and lymphoid	DOHH2	9.8
Haematopoietic and lymphoid	EB1	9.7
Haematopoietic and lymphoid	EB2	10.3
Haematopoietic and lymphoid	EHEB	9.4
Haematopoietic and lymphoid	EJM	9.2
Haematopoietic and lymphoid	EM2	9.3
Haematopoietic and lymphoid	EOL1	9.5
Haematopoietic and lymphoid	F36P	9.5
Haematopoietic and lymphoid	GA10	9.9
Haematopoietic and lymphoid	GDM1	9.6
Haematopoietic and lymphoid	GRANTA519	10
Haematopoietic and lymphoid	HDLM2	9.4
Haematopoietic and lymphoid	HDMYZ	8.9
Haematopoietic and lymphoid	HEL9217	9.6
Haematopoietic and lymphoid	HEL	9.4
Haematopoietic and lymphoid	HH	9.6
Haematopoietic and lymphoid	HL60	9.7
Haematopoietic and lymphoid	HPBALL	10.4
Haematopoietic and lymphoid	HS604T	8.8
Haematopoietic and lymphoid	HS611T	8.9
Haematopoietic and lymphoid	HS616T	8.1
Haematopoietic and lymphoid	HS751T	8.4
Haematopoietic and lymphoid	HT	10
Haematopoietic and lymphoid	HTK	10.2
Haematopoietic and lymphoid	HUNS1	9
Haematopoietic and lymphoid	HUT102	8.7
Haematopoietic and lymphoid	HUT78	9
Haematopoietic and lymphoid	JEKO1	9.9
Haematopoietic and lymphoid	JK1	9.7
Haematopoietic and lymphoid	JM1	10.2
Haematopoietic and lymphoid	JURKAT	10.1
Haematopoietic and lymphoid	JURLMK1	9.9
Haematopoietic and lymphoid	JVM2	9
Haematopoietic and lymphoid	JVM3	9.6
Haematopoietic and lymphoid	K562	9
Haematopoietic and lymphoid	KARPAS299	11
Haematopoietic and lymphoid	KARPAS422	9.8
Haematopoietic and lymphoid	KARPAS620	9.9
Haematopoietic and lymphoid	KASUMI1	9.4
Haematopoietic and lymphoid	KASUMI2	10
Haematopoietic and lymphoid	KASUMI6	9.6
Haematopoietic and lymphoid	KCL22	9.6
Haematopoietic and lymphoid	KE37	10.3
Haematopoietic and lymphoid	KE97	9
Haematopoietic and lymphoid	KG1	9.2
Haematopoietic and lymphoid	KHM1B	10
Haematopoietic and lymphoid	KIJK	9.6
Haematopoietic and lymphoid	KMH2	9.5
Haematopoietic and lymphoid	KMM1	10
Haematopoietic and lymphoid	KMS11	10.7
Haematopoietic and lymphoid	KMS12BM	9.4
Haematopoietic and lymphoid	KMS18	9.4
Haematopoietic and lymphoid	KMS20	10.7
Haematopoietic and lymphoid	KMS21BM	9.3
Haematopoietic and lymphoid	KMS26	9.4
Haematopoietic and lymphoid	KMS27	9.5
Haematopoietic and lymphoid	KMS28BM	9.5
Haematopoietic and lymphoid	KMS34	8.9
Haematopoietic and lymphoid	KO52	9.4
Haematopoietic and lymphoid	KOPN8	9.5
Haematopoietic and lymphoid	KU812	9.4
Haematopoietic and lymphoid	KYO1	9.7
Haematopoietic and lymphoid	L1236	8.6
Haematopoietic and lymphoid	L363	10
Haematopoietic and lymphoid	L428	8.6
Haematopoietic and lymphoid	L540	9.7
Haematopoietic and lymphoid	LAMA84	9.5
Haematopoietic and lymphoid	LOUCY	9.7
Haematopoietic and lymphoid	LP1	10.5
Haematopoietic and lymphoid	M07E	9.4
Haematopoietic and lymphoid	MC116	9.9
Haematopoietic and lymphoid	ME1	8.9
Haematopoietic and lymphoid	MEC1	9.7
Haematopoietic and lymphoid	MEC2	9.4
Haematopoietic and lymphoid	MEG01	8.6
Haematopoietic and lymphoid	MHHCALL2	10
Haematopoietic and lymphoid	MHHCALL3	10.2
Haematopoietic and lymphoid	MHHCALL4	10.5
Haematopoietic and lymphoid	MINO	9.2
Haematopoietic and lymphoid	MJ	8.9
Haematopoietic and lymphoid	MM1S	9.1
Haematopoietic and lymphoid	MOLM13	8.8
Haematopoietic and lymphoid	MOLM16	9.4
Haematopoietic and lymphoid	MOLM6	10.1
Haematopoietic and lymphoid	MOLP2	9.3
Haematopoietic and lymphoid	MOLP8	11.2
Haematopoietic and lymphoid	MOLT13	10.4
Haematopoietic and lymphoid	MOLT16	9.7
Haematopoietic and lymphoid	MOLT4	9.5
Haematopoietic and lymphoid	MONOMAC1	9.6
Haematopoietic and lymphoid	MONOMAC6	9.6
Haematopoietic and lymphoid	MOTN1	9.6
Haematopoietic and lymphoid	MUTZ5	10.2
Haematopoietic and lymphoid	MV411	9.2
Haematopoietic and lymphoid	NALM19	10
Haematopoietic and lymphoid	NALM1	10.5
Haematopoietic and lymphoid	NALM6	10.5
Haematopoietic and lymphoid	NAMALWA	9.9
Haematopoietic and lymphoid	NB4	9
Haematopoietic and lymphoid	NCIH929	9.2
Haematopoietic and lymphoid	NCO2	9.2
Haematopoietic and lymphoid	NOMO1	8.7
Haematopoietic and lymphoid	NUDHL1	9.8
Haematopoietic and lymphoid	NUDUL1	10.4
Haematopoietic and lymphoid	OCIAML2	9.5
Haematopoietic and lymphoid	OCIAML3	10.4
Haematopoietic and lymphoid	OCIAML5	9.8
Haematopoietic and lymphoid	OCILY10	9.3
Haematopoietic and lymphoid	OCILY19	10.4
Haematopoietic and lymphoid	OCILY3	9
Haematopoietic and lymphoid	OCIM1	9.7
Haematopoietic and lymphoid	OPM2	10.5
Haematopoietic and lymphoid	P12ICHIKAWA	10.3
Haematopoietic and lymphoid	P31FUJ	9.1
Haematopoietic and lymphoid	P3HR1	9.3
Haematopoietic and lymphoid	PCM6	9.4
Haematopoietic and lymphoid	PEER	9.4
Haematopoietic and lymphoid	PF382	10.5
Haematopoietic and lymphoid	PFEIFFER	9.1
Haematopoietic and lymphoid	PL21	9.8
Haematopoietic and lymphoid	RAJI	9
Haematopoietic and lymphoid	RCHACV	10.5
Haematopoietic and lymphoid	REC1	9.4
Haematopoietic and lymphoid	REH	9.3
Haematopoietic and lymphoid	RI1	9.3
Haematopoietic and lymphoid	RL	9.1
Haematopoietic and lymphoid	RPMI8226	8.9
Haematopoietic and lymphoid	RPMI8402	10.4
Haematopoietic and lymphoid	RS411	9.3
Haematopoietic and lymphoid	SEM	9.4
Haematopoietic and lymphoid	SET2	9.5
Haematopoietic and lymphoid	SIGM5	9.8
Haematopoietic and lymphoid	SKM1	9.5
Haematopoietic and lymphoid	SKMM2	9.5
Haematopoietic and lymphoid	SR786	10.2
Haematopoietic and lymphoid	ST486	10.3
Haematopoietic and lymphoid	SUDHL10	10.3
Haematopoietic and lymphoid	SUDHL1	9.8
Haematopoietic and lymphoid	SUDHL4	10
Haematopoietic and lymphoid	SUDHL5	9.8
Haematopoietic and lymphoid	SUDHL6	9.7
Haematopoietic and lymphoid	SUDHL8	10.2
Haematopoietic and lymphoid	SUPB15	9.7
Haematopoietic and lymphoid	SUPHD1	11
Haematopoietic and lymphoid	SUPM2	9.8
Haematopoietic and lymphoid	SUPT11	10.4
Haematopoietic and lymphoid	SUPT1	9.8
Haematopoietic and lymphoid	TALL1	10.2
Haematopoietic and lymphoid	TF1	9.3
Haematopoietic and lymphoid	THP1	9.8
Haematopoietic and lymphoid	TO175T	8.5
Haematopoietic and lymphoid	TOLEDO	9.9
Haematopoietic and lymphoid	U266B1	9.1
Haematopoietic and lymphoid	U937	9.3
Haematopoietic and lymphoid	UT7	10.1
Haematopoietic and lymphoid	WSUDLCL2	10.2
Kidney	769P	8.5
Kidney	786O	8.4
Kidney	A498	9
Kidney	A704	8.9
Kidney	ACHN	8.6
Kidney	BFTC909	8.9
Kidney	CAKI1	9.1
Kidney	CAKI2	8.4
Kidney	CAL54	9.2
Kidney	KMRC1	8.6
Kidney	KMRC20	9.1
Kidney	KMRC2	8.5
Kidney	KMRC3	8.7
Kidney	OSRC2	8.6
Kidney	RCC10RGB	8.9
Kidney	SNU1272	9.2
Kidney	SNU349	8.5
Kidney	TUHR10TKB	9
Kidney	TUHR14TKB	9.2
Kidney	TUHR4TKB	9
Kidney	VMRCRCW	8.9
Kidney	VMRCRCZ	9
Large intestine	C2BBE1	8.7
Large intestine	CCK81	8.4
Large intestine	CL11	8.6
Large intestine	CL14	9.1
Large intestine	CL34	8.5
Large intestine	CL40	8.6
Large intestine	COLO205	8.4
Large intestine	COLO320	10
Large intestine	COLO678	10.2
Large intestine	CW2	8.5
Large intestine	DLD1	8.4
Large intestine	GP2D	8.6
Large intestine	HCC56	9
Large intestine	HCT116	8.5
Large intestine	HCT15	8.6
Large intestine	HS675T	7.9
Large intestine	HS698T	8.7
Large intestine	HT115	8.6
Large intestine	HT29	8.8
Large intestine	HT55	9
Large intestine	KM12	8.6
Large intestine	LOVO	8.1
Large intestine	LS1034	8.3
Large intestine	LS123	8.6
Large intestine	LS180	8.5
Large intestine	LS411N	8.2
Large intestine	LS513	8.5
Large intestine	MDST8	8.7
Large intestine	NCIH508	9.2
Large intestine	NCIH716	8.9
Large intestine	NCIH747	8.8
Large intestine	OUMS23	9.6
Large intestine	RCM1	9.1
Large intestine	RKO	8.1
Large intestine	SKCO1	9.4
Large intestine	SNU1040	8.6
Large intestine	SNU1197	8.4
Large intestine	SNU175	9.6
Large intestine	SNU283	8.6
Large intestine	SNU407	9.8
Large intestine	SNU503	9
Large intestine	SNU61	8.8
Large intestine	SNU81	8.9
Large intestine	SNUC1	7.5
Large intestine	SNUC2A	8.6
Large intestine	SNUC4	8.1
Large intestine	SNUC5	9.1
Large intestine	SW1116	7.9
Large intestine	SW1417	8.4
Large intestine	SW1463	7.9
Large intestine	SW403	8.3
Large intestine	SW480	8
Large intestine	SW48	8.6
Large intestine	SW620	8.7
Large intestine	SW837	8.9
Large intestine	SW948	8.5
Large intestine	T84	7.9
Liver	ALEXANDERCELLS	8.4
Liver	C3A	8.2
Liver	HEP3B217	9.5
Liver	HEPG2	8.1
Liver	HLE	7.8
Liver	HLF	8.5
Liver	HUH1	9.1
Liver	HUH6	8.9
Liver	HUH7	8.3
Liver	JHH1	8.5
Liver	JHH2	8.4
Liver	JHH4	9.2
Liver	JHH5	9.3
Liver	JHH6	8.9
Liver	JHH7	9.1
Liver	LI7	9.1
Liver	PLCPRF5	8.4
Liver	SKHEP1	8.8
Liver	SNU182	8.8
Liver	SNU387	9.1
Liver	SNU398	9.4
Liver	SNU423	8.5
Liver	SNU449	9.3
Liver	SNU475	9.6
Liver	SNU761	9.5
Liver	SNU878	8.5
Liver	SNU886	9
Lung	A549	8.2
Lung	ABC1	8.4
Lung	BEN	9.8
Lung	CAL12T	8.8
Lung	CALU1	8.6
Lung	CALU3	9.5
Lung	CALU6	8.9
Lung	CHAGOK1	9.8
Lung	COLO668	9.1
Lung	COLO699	9.4
Lung	CORL105	9.3
Lung	CORL23	8.3
Lung	CORL24	10.3
Lung	CORL279	9.7
Lung	CORL311	9.9
Lung	CORL47	9.8
Lung	CORL51	10.1
Lung	CORL88	10
Lung	CORL95	9.7
Lung	CPCN	9.4
Lung	DMS114	9.7
Lung	DMS153	10.1
Lung	DMS273	10.9
Lung	DMS454	9.1
Lung	DMS53	8.7
Lung	DMS79	9.4
Lung	DV90	5.4
Lung	EBC1	8
Lung	EPLC272H	7.8
Lung	HARA	8.1
Lung	HCC1171	10.2
Lung	HCC1195	9.3
Lung	HCC15	8.7
Lung	HCC2279	7.7
Lung	HCC2935	8.6
Lung	HCC33	10.4
Lung	HCC366	8.8
Lung	HCC4006	8.6
Lung	HCC44	8.8
Lung	HCC78	9.2
Lung	HCC827	8.7
Lung	HCC95	8
Lung	HLC1	9.3
Lung	HLFA	7.9
Lung	HS229T	8
Lung	HS618T	8
Lung	IALM	9.4
Lung	KNS62	8.3
Lung	LC1F	9.2
Lung	LC1SQSF	9.1
Lung	LCLC103H	8.9
Lung	LCLC97TM1	10.1
Lung	LK2	10.5
Lung	LOUNH91	8.5
Lung	LU65	9
Lung	LU99	9.4
Lung	LUDLU1	8.9
Lung	LXF289	9.7
Lung	MORCPR	9.6
Lung	NCIH1048	10
Lung	NCIH1092	10.2
Lung	NCIH1105	10.7
Lung	NCIH1155	8.9
Lung	NCIH1184	10
Lung	NCIH1299	8.6
Lung	NCIH1339	9.1
Lung	NCIH1341	9.5
Lung	NCIH1355	9
Lung	NCIH1373	9.2
Lung	NCIH1385	9.4
Lung	NCIH1395	9.7
Lung	NCIH1435	8.8
Lung	NCIH1436	10.1
Lung	NCIH1437	10.6
Lung	NCIH146	9.6
Lung	NCIH1563	8.6
Lung	NCIH1568	9.4
Lung	NCIH1573	9.3
Lung	NCIH1581	9.7
Lung	NCIH1618	10.1
Lung	NCIH1623	9.8
Lung	NCIH1648	7.9
Lung	NCIH1650	8.6
Lung	NCIH1651	9.3
Lung	NCIH1666	8.9
Lung	NCIH1693	8.2
Lung	NCIH1694	10.2
Lung	NCIH1703	9.4
Lung	NCIH1734	9.3
Lung	NCIH1755	8.5
Lung	NCIH1781	8.8
Lung	NCIH1792	8.8
Lung	NCIH1793	8.4
Lung	NCIH1836	9.5
Lung	NCIH1838	9
Lung	NCIH1869	8.7
Lung	NCIH1876	11.5
Lung	NCIH1915	8.4
Lung	NCIH1930	9.3
Lung	NCIH1944	8.8
Lung	NCIH1963	10.3
Lung	NCIH196	9.1
Lung	NCIH1975	8.9
Lung	NCIH2009	9.1
Lung	NCIH2023	8.6
Lung	NCIH2029	9.3
Lung	NCIH2030	8.8
Lung	NCIH2066	9.4
Lung	NCIH2081	10.3
Lung	NCIH2085	9.4
Lung	NCIH2087	8.7
Lung	NCIH209	9.3
Lung	NCIH2106	9.9
Lung	NCIH2110	9.6
Lung	NCIH211	9.2
Lung	NCIH2122	9.1
Lung	NCIH2126	10
Lung	NCIH2141	10.4
Lung	NCIH2170	8.8
Lung	NCIH2171	9.4
Lung	NCIH2172	8.9
Lung	NCIH2196	9.5
Lung	NCIH2227	10.3
Lung	NCIH2228	8.6
Lung	NCIH226	8.2
Lung	NCIH2286	9.3
Lung	NCIH2291	7.9
Lung	NCIH2342	8.5
Lung	NCIH2347	8.4
Lung	NCIH23	9.1
Lung	NCIH2405	9
Lung	NCIH2444	8.6
Lung	NCIH292	8.8
Lung	NCIH322	8.3
Lung	NCIH3255	8.3
Lung	NCIH358	9.1
Lung	NCIH441	8.9
Lung	NCIH446	9.4
Lung	NCIH460	8.4
Lung	NCIH510	8.8
Lung	NCIH520	9.2
Lung	NCIH522	9.7
Lung	NCIH524	8.8
Lung	NCIH526	10.6
Lung	NCIH596	9
Lung	NCIH647	8.9
Lung	NCIH650	9.3
Lung	NCIH661	8.6
Lung	NCIH69	9.5
Lung	NCIH727	8.9
Lung	NCIH810	9.5
Lung	NCIH82	9.8
Lung	NCIH838	8.7
Lung	NCIH841	10.3
Lung	NCIH854	9.2
Lung	NCIH889	9.9
Lung	PC14	7.8
Lung	RERFLCAD1	8.3
Lung	RERFLCAD2	8.1
Lung	RERFLCAI	8.9
Lung	RERFLCKJ	9.9
Lung	RERFLCMS	8.5
Lung	RERFLCSQ1	8.4
Lung	SBC5	9.8
Lung	SCLC21H	10.5
Lung	SHP77	9.7
Lung	SKLU1	7.8
Lung	SKMES1	8.7
Lung	SQ1	7.8
Lung	SW1271	8.6
Lung	SW1573	9.6
Lung	SW900	9
Lung	VMRCLCD	9.2
Lung	VMRCLCP	8.9
Oesophagus	COLO680N	9.6
Oesophagus	ECGI10	9.4
Oesophagus	KYSE140	8.5
Oesophagus	KYSE150	8.7
Oesophagus	KYSE180	8.2
Oesophagus	KYSE270	9.1
Oesophagus	KYSE30	9.3
Oesophagus	KYSE410	8.2
Oesophagus	KYSE450	8.6
Oesophagus	KYSE510	9.3
Oesophagus	KYSE520	8.9
Oesophagus	KYSE70	8.9
Oesophagus	OE19	8.4
Oesophagus	OE33	8.5
Oesophagus	TE10	8.4
Oesophagus	TE11	7.9
Oesophagus	TE14	9.2
Oesophagus	TE15	8.4
Oesophagus	TE1	8.8
Oesophagus	TE4	8.4
Oesophagus	TE5	8.9
Oesophagus	TE6	9.4
Oesophagus	TE8	9.1
Oesophagus	TE9	8.4
Oesophagus	TT	9.2
Ovary	59M	8.9
Ovary	A2780	10
Ovary	CAOV3	8.3
Ovary	CAOV4	11.2
Ovary	COLO704	10.3
Ovary	COV318	9.8
Ovary	COV362	9
Ovary	COV434	8.8
Ovary	COV504	10.1
Ovary	COV644	9.4
Ovary	EFO21	9.4
Ovary	EFO27	8.7
Ovary	ES2	8.5
Ovary	FUOV1	9.3
Ovary	HEYA8	8.3
Ovary	HS571T	8.3
Ovary	IGROV1	8.8
Ovary	JHOC5	9
Ovary	JHOM1	8.5
Ovary	JHOM2B	9.2
Ovary	JHOS2	8.9
Ovary	JHOS4	8.9
Ovary	KURAMOCHI	10
Ovary	MCAS	8.7
Ovary	NIHOVCAR3	9.6
Ovary	OAW28	8.9
Ovary	OAW42	9.1
Ovary	OC314	8.8
Ovary	OC316	8.6
Ovary	ONCODG1	9.9
Ovary	OV56	9
Ovary	OV7	8.9
Ovary	OV90	9.1
Ovary	OVCAR4	8.8
Ovary	OVCAR8	8.6
Ovary	OVISE	8.3
Ovary	OVK18	9.3
Ovary	OVKATE	8.7
Ovary	OVMANA	9.7
Ovary	OVSAHO	8.8
Ovary	OVTOKO	7.8
Ovary	RMGI	8
Ovary	RMUGS	8.3
Ovary	SKOV3	9.1
Ovary	SNU119	9.9
Ovary	SNU840	8.8
Ovary	SNU8	9
Ovary	TOV112D	10
Ovary	TOV21G	8.7
Ovary	TYKNU	8.6
Pancreas	ASPC1	9.4
Pancreas	BXPC3	8.2
Pancreas	CAPAN1	9.4
Pancreas	CAPAN2	8.7
Pancreas	CFPAC1	9.2
Pancreas	DANG	7.8
Pancreas	HPAC	10
Pancreas	HPAFII	8.2
Pancreas	HS766T	8.5
Pancreas	HUPT3	8
Pancreas	HUPT4	7.6
Pancreas	KCIMOH1	9
Pancreas	KLM1	8.9
Pancreas	KP2	9.1
Pancreas	KP3	9.2
Pancreas	KP4	9.5
Pancreas	L33	9.5
Pancreas	MIAPACA2	9.6
Pancreas	PANC0203	8.9
Pancreas	PANC0213	9.5
Pancreas	PANC0327	8.4
Pancreas	PANC0403	8.4
Pancreas	PANC0504	8.2
Pancreas	PANC0813	8.8
Pancreas	PANC1005	8.9
Pancreas	PANC1	8.7
Pancreas	PATU8902	7.8
Pancreas	PATU8988S	8.8
Pancreas	PATU8988T	8.8
Pancreas	PK1	7.9
Pancreas	PK45H	8.9
Pancreas	PK59	8.1
Pancreas	PL45	8.7
Pancreas	PSN1	8.9
Pancreas	QGP1	9.9
Pancreas	SNU213	8.9
Pancreas	SNU324	9.7
Pancreas	SNU410	9
Pancreas	SU8686	9.3
Pancreas	SUIT2	8.8
Pancreas	SW1990	7.8
Pancreas	T3M4	8.5
Pancreas	TCCPAN2	8.3
Pancreas	YAPC	9.4
Pleura	ACCMESO1	8.1
Pleura	DM3	7.8
Pleura	ISTMES1	8.3
Pleura	ISTMES2	8.3
Pleura	JL1	8.9
Pleura	MPP89	8.6
Pleura	MSTO211H	8.3
Pleura	NCIH2052	8.2
Pleura	NCIH2452	8.1
Pleura	NCIH28	9.3
Prostate	22RV1	9.3
Prostate	DU145	9
Prostate	LNCAPCLONEFGC	9.1
Prostate	MDAPCA2B	8.5
Prostate	NCIH660	9.5
Prostate	PC3	8.5
Prostate	VCAP	9.2
Salivary gland	A253	8.2
Salivary gland	YD15	8.1
Skin	A101D	8.3
Skin	A2058	9.1
Skin	A375	8.8
Skin	C32	8.3
Skin	CHL1	9.2
Skin	CJM	8.4
Skin	COLO679	9.4
Skin	COLO741	9
Skin	COLO783	8.9
Skin	COLO792	8.5
Skin	COLO800	8.9
Skin	COLO818	8.5
Skin	COLO829	8.7
Skin	COLO849	9.1
Skin	G361	8.8
Skin	GRM	8.8
Skin	HMCB	9.3
Skin	HS294T	8.4
Skin	HS600T	7.7
Skin	HS688AT	8.2
Skin	HS695T	9.6
Skin	HS839T	8.1
Skin	HS852T	9.4
Skin	HS895T	7.5
Skin	HS934T	8.3
Skin	HS936T	9.2
Skin	HS939T	8.5
Skin	HS940T	8.5
Skin	HS944T	8.3
Skin	HT144	8.3
Skin	IGR1	9.1
Skin	IGR37	8.7
Skin	IGR39	8.4
Skin	IPC298	8.6
Skin	K029AX	8.9
Skin	LOXIMVI	8.6
Skin	MALME3M	8.8
Skin	MDAMB435S	8.6
Skin	MELHO	8.4
Skin	MELJUSO	8.5
Skin	MEWO	9.2
Skin	RPMI7951	8.6
Skin	RVH421	8.4
Skin	SH4	8.9
Skin	SKMEL1	8.2
Skin	SKMEL24	8.5
Skin	SKMEL28	8.5
Skin	SKMEL2	8.8
Skin	SKMEL30	8.9
Skin	SKMEL31	8.7
Skin	SKMEL3	8.4
Skin	SKMEL5	8.7
Skin	UACC257	8.6
Skin	UACC62	8.4
Skin	WM115	8.6
Skin	WM1799	9.4
Skin	WM2664	8.4
Skin	WM793	9.3
Skin	WM88	9.7
Skin	WM983B	8.7
Small intestine	HUTU80	9.4
Soft tissue	A204	8.5
Soft tissue	G401	9
Soft tissue	G402	8.7
Soft tissue	GCT	8.1
Soft tissue	HS729	9.3
Soft tissue	HT1080	8.3
Soft tissue	KYM1	9
Soft tissue	MESSA	9
Soft tissue	RD	9.3
Soft tissue	RH30	9.3
Soft tissue	RH41	10
Soft tissue	RKN	8.6
Soft tissue	S117	9.1
Soft tissue	SJRH30	9.3
Soft tissue	SKLMS1	7.9
Soft tissue	SKUT1	9
Soft tissue	TE125T	8.4
Soft tissue	TE159T	8.1
Soft tissue	TE441T	9.6
Soft tissue	TE617T	9.3
Stomach	2313287	8.9
Stomach	AGS	9
Stomach	AZ521	9.2
Stomach	ECC10	9.4
Stomach	ECC12	9.5
Stomach	FU97	9
Stomach	GCIY	9.1
Stomach	GSS	9.4
Stomach	GSU	8.4
Stomach	HGC27	9.6
Stomach	HS746T	8.2
Stomach	HUG1N	8.4
Stomach	IM95	8.3
Stomach	KATOIII	7.8
Stomach	KE39	8.5
Stomach	LMSU	9
Stomach	MKN1	8.4
Stomach	MKN45	8.9
Stomach	MKN74	9.3
Stomach	MKN7	8
Stomach	NCCSTCK140	9.2
Stomach	NCIN87	8.8
Stomach	NUGC2	8.1
Stomach	NUGC3	8.6
Stomach	NUGC4	8.6
Stomach	OCUM1	9.1
Stomach	RERFGC1B	9.5
Stomach	SH10TC	8.5
Stomach	SNU16	8.7
Stomach	SNU1	9
Stomach	SNU216	9.1
Stomach	SNU520	8.5
Stomach	SNU5	8.8
Stomach	SNU601	8.6
Stomach	SNU620	8.5
Stomach	SNU668	8.9
Stomach	SNU719	9.1
Stomach	TGBC11TKB	9.5
Thyroid	8305C	9.1
Thyroid	8505C	8.1
Thyroid	BCPAP	9.2
Thyroid	BHT101	10.1
Thyroid	CAL62	9.2
Thyroid	CGTHW1	8.9
Thyroid	FTC133	8.3
Thyroid	FTC238	8.9
Thyroid	ML1	9
Thyroid	SW579	8.2
Thyroid	TT2609C02	8.5
Thyroid	TT	10.4
Upper aerodigestive tract	BHY	8.8
Upper aerodigestive tract	BICR16	7.8
Upper aerodigestive tract	BICR18	8.3
Upper aerodigestive tract	BICR22	8.2
Upper aerodigestive tract	BICR31	8.4
Upper aerodigestive tract	BICR56	8.5
Upper aerodigestive tract	BICR6	8.3
Upper aerodigestive tract	CAL27	8.5
Upper aerodigestive tract	CAL33	9
Upper aerodigestive tract	DETROIT562	8.1
Upper aerodigestive tract	FADU	9.1
Upper aerodigestive tract	HS840T	8.1
Upper aerodigestive tract	HSC2	8.3
Upper aerodigestive tract	HSC3	8.4
Upper aerodigestive tract	HSC4	9.6
Upper aerodigestive tract	PECAPJ15	8.9
Upper aerodigestive tract	PECAPJ34CLONEC12	8.3
Upper aerodigestive tract	PECAPJ41CLONED2	8.5
Upper aerodigestive tract	PECAPJ49	8.7
Upper aerodigestive tract	SCC15	8.8
Upper aerodigestive tract	SCC25	8.4
Upper aerodigestive tract	SCC4	7.9
Upper aerodigestive tract	SCC9	9.2
Upper aerodigestive tract	SNU1076	8.7
Upper aerodigestive tract	SNU1214	7.7
Upper aerodigestive tract	SNU46	9.1
Upper aerodigestive tract	SNU899	8.5
Upper aerodigestive tract	YD10B	9
Upper aerodigestive tract	YD38	9.6
Upper aerodigestive tract	YD8	9
Urinary tract	5637	8.5
Urinary tract	639V	9.1
Urinary tract	647V	9.3
Urinary tract	BC3C	8.1
Urinary tract	BFTC905	9.2
Urinary tract	CAL29	8.5
Urinary tract	HS172T	8.6
Urinary tract	HT1197	7.5
Urinary tract	HT1376	9.4
Urinary tract	J82	8.3
Urinary tract	JMSU1	10.4
Urinary tract	KMBC2	8.8
Urinary tract	KU1919	8.9
Urinary tract	RT11284	8.5
Urinary tract	RT112	8
Urinary tract	RT4	8.6
Urinary tract	SCABER	8.2
Urinary tract	SW1710	9.6
Urinary tract	SW780	9.3
Urinary tract	T24	8.7
Urinary tract	TCCSUP	9.4
Urinary tract	UMUC1	8.6
Urinary tract	UMUC3	8.7
Urinary tract	VMCUB1	9.9

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	19.9
Adrenal gland	29
Appendix	21.2
Bone marrow	26.1
Breast	33.3
Cerebral cortex	34
Cervix, uterine	33.8
Colon	17.5
Duodenum	15.8
Endometrium	58.8
Epididymis	66.8
Esophagus	18
Fallopian tube	55.9
Gallbladder	37.5
Heart muscle	10.7
Kidney	18.4
Liver	8.6
Lung	31.7
Lymph node	24.9
Ovary	65.6
Pancreas	4.1
Parathyroid gland	74.9
Placenta	22.6
Prostate	34.4
Rectum	23.6
Salivary gland	10.5
Seminal vesicle	34.1
Skeletal muscle	9.1
Skin	44.4
Small intestine	17.7
Smooth muscle	41.5
Spleen	34.3
Stomach	16.5
Testis	49.2
Thyroid gland	43.4
Tonsil	20.6
Urinary bladder	20.3

> Text Mining based Expression [ TOP ]
There is no record.

Summary
Symbol	POGZ
Name	pogo transposable element derived with ZNF domain
Aliases	KIAA0461; ZNF635m; ZNF280E; zinc finger protein 280E; putative protein product of Nbla00003; MRD37; ZNF635; ......
Location	1q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.626	2.72e-45	4.5	46	49.5	Gain
BRCA	Breast invasive carcinoma	1075	0.657	1.21e-133	2	26	72	Gain
CESC	Cervical and endocervical cancers	292	0.496	1.47e-19	2.1	44.5	53.4	Gain
COAD	Colon adenocarcinoma	449	0.415	4.45e-20	9.8	70.4	19.8	Neutral
ESCA	Esophageal carcinoma	183	0.62	7.55e-21	3.8	46.4	49.7	Gain
GBM	Glioblastoma multiforme	147	0.25	0.00222	2	79.6	18.4	Neutral
HNSC	Head and Neck squamous cell carcinoma	514	0.472	6.26e-30	7	67.7	25.3	Neutral
KIRC	Kidney renal clear cell carcinoma	525	0.336	2.35e-15	6.3	82.1	11.6	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	0.249	1.87e-05	6.6	87.8	5.6	Neutral
LAML	Acute Myeloid Leukemia	166	0.173	0.0262	0	98.8	1.2	Neutral
LGG	Brain Lower Grade Glioma	513	0.141	0.00138	1.9	91	7	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.628	2.74e-41	0.8	25.8	73.4	Gain
LUAD	Lung adenocarcinoma	512	0.586	1.5e-48	1.8	25.2	73	Gain
LUSC	Lung squamous cell carcinoma	498	0.572	1.42e-44	4	43.8	52.2	Gain
OV	Ovarian serous cystadenocarcinoma	300	0.572	1.92e-27	2	33	65	Gain
PAAD	Pancreatic adenocarcinoma	177	0.477	1.88e-11	3.4	65	31.6	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	0.507	5.88e-12	8	74.7	17.3	Neutral
PRAD	Prostate adenocarcinoma	491	0.411	2.12e-21	0.8	91.2	7.9	Neutral
READ	Rectum adenocarcinoma	164	0.388	2.83e-07	7.9	63.4	28.7	Neutral
SARC	Sarcoma	255	0.543	6.42e-21	5.9	53.7	40.4	Gain
SKCM	Skin Cutaneous Melanoma	367	0.723	1.42e-60	3.8	41.7	54.5	Gain
STAD	Stomach adenocarcinoma	413	0.553	1.93e-34	2.2	61.5	36.3	Gain
TGCT	Testicular Germ Cell Tumors	150	0.424	6.65e-08	1.3	53.3	45.3	Gain
THCA	Thyroid carcinoma	497	0.225	3.81e-07	0.6	94	5.4	Neutral
THYM	Thymoma	119	0.223	0.0147	0	80.7	19.3	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.676	5.25e-73	0.2	53.4	46.4	Gain

Summary
Symbol	POGZ
Name	pogo transposable element derived with ZNF domain
Aliases	KIAA0461; ZNF635m; ZNF280E; zinc finger protein 280E; putative protein product of Nbla00003; MRD37; ZNF635; ......
Location	1q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

[ TOP ]

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.349	1.78e-13	17	408	-0.01	0.0367	NS/NA
BRCA	Breast invasive carcinoma	-0.37	0	83	785	-0.013	7e-07	NS/NA
CESC	Cervical and endocervical cancers	-0.328	4.19e-09	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.241	1.58e-05	19	297	-0.001	0.711	NS/NA
ESCA	Esophageal carcinoma	-0.273	0.000124	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.292	0.0185	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.251	3.37e-09	20	522	0.001	0.002	NS/NA
KIRC	Kidney renal clear cell carcinoma	-0.205	0.00014	24	319	-0.001	0.759	NS/NA
KIRP	Kidney renal papillary cell carcinoma	-0.143	0.0135	23	275	-0.015	1.23e-08	NS/NA
LAML	Acute Myeloid Leukemia	-0.155	0.0443	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	-0.1	0.0209	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.27	2.6e-08	41	373	-0.003	0.000462	NS/NA
LUAD	Lung adenocarcinoma	-0.225	7.03e-07	21	456	-0.053	4.84e-13	NS/NA
LUSC	Lung squamous cell carcinoma	-0.349	4.03e-12	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	-0.583	0.108	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.231	0.00173	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.304	2.49e-05	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.173	6.18e-05	35	498	0.028	0.000703	NS/NA
READ	Rectum adenocarcinoma	-0.109	0.278	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.341	1.68e-08	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.394	0	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.381	3.17e-14	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.634	0	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.137	0.0012	50	509	0	0.734	NS/NA
THYM	Thymoma	-0.155	0.0878	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.337	1.14e-13	34	431	-0.011	0.0802	NS/NA

Summary
Symbol	POGZ
Name	pogo transposable element derived with ZNF domain
Aliases	KIAA0461; ZNF635m; ZNF280E; zinc finger protein 280E; putative protein product of Nbla00003; MRD37; ZNF635; ......
Location	1q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Level	Level Name
Adrenal gland	3	High
Appendix	2	Medium
Bone marrow	3	High
Breast	3	High
Bronchus	3	High
Caudate	3	High
Cerebellum	3	High
Cerebral cortex	3	High
Cervix, uterine	3	High
Colon	3	High
Duodenum	3	High
Endometrium	3	High
Epididymis	3	High
Esophagus	3	High
Fallopian tube	2	Medium
Gallbladder	3	High
Heart muscle	2	Medium
Hippocampus	3	High
Kidney	2	Medium
Liver	2	Medium
Lung	3	High
Lymph node	2	Medium
Nasopharynx	3	High
Oral mucosa	3	High
Ovary	2	Medium
Pancreas	1	Low
Parathyroid gland	2	Medium
Placenta	3	High
Prostate	1	Low
Rectum	3	High
Salivary gland	3	High
Seminal vesicle	2	Medium
Skeletal muscle	2	Medium
Skin	3	High
Small intestine	3	High
Smooth muscle	2	Medium
Soft tissue	2	Medium
Spleen	2	Medium
Stomach	3	High
Testis	3	High
Thyroid gland	3	High
Tonsil	2	Medium
Urinary bladder	3	High
Vagina	3	High

Summary
Symbol	POGZ
Name	pogo transposable element derived with ZNF domain
Aliases	KIAA0461; ZNF635m; ZNF280E; zinc finger protein 280E; putative protein product of Nbla00003; MRD37; ZNF635; ......
Location	1q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.128	NS	24476821
BRCA	Breast invasive carcinoma	521	8.6e-06	Significant	23000897
COAD	Colon adenocarcinoma	149	0.215	NS	22810696
GBM	Glioblastoma multiforme	157	1e-06	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	4.37e-16	Significant	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.00176	Significant	26536169
LGG	Brain Lower Grade Glioma	513	1.33e-19	Significant	26824661
LUAD	Lung adenocarcinoma	230	0.000225	Significant	25079552
LUSC	Lung squamous cell carcinoma	178	0.00038	Significant	22960745
OV	Ovarian serous cystadenocarcinoma	287	8.67e-05	Significant	21720365
PRAD	Prostate adenocarcinoma	333	5.02e-09	Significant	26544944
READ	Rectum adenocarcinoma	67	0.702	NS	22810696
SKCM	Skin Cutaneous Melanoma	315	0.000233	Significant	26091043
STAD	Stomach adenocarcinoma	277	0.000117	Significant	25079317
THCA	Thyroid carcinoma	391	0.0318	Significant	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	0.00415	Significant	23636398

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	0.514	0.00158	Longer
BRCA	Breast invasive carcinoma	1079	0.984	0.945	NS
CESC	Cervical and endocervical cancers	291	1.178	0.64	NS
COAD	Colon adenocarcinoma	439	1.515	0.149	NS
ESCA	Esophageal carcinoma	184	0.909	0.756	NS
GBM	Glioblastoma multiforme	158	0.758	0.289	NS
HNSC	Head and Neck squamous cell carcinoma	518	0.571	0.00539	Longer
KIRC	Kidney renal clear cell carcinoma	531	1.507	0.0409	Shorter
KIRP	Kidney renal papillary cell carcinoma	287	1.727	0.215	NS
LAML	Acute Myeloid Leukemia	149	0.913	0.771	NS
LGG	Brain Lower Grade Glioma	511	0.521	0.011	Longer
LIHC	Liver hepatocellular carcinoma	365	0.961	0.874	NS
LUAD	Lung adenocarcinoma	502	0.983	0.936	NS
LUSC	Lung squamous cell carcinoma	494	0.938	0.742	NS
OV	Ovarian serous cystadenocarcinoma	303	1.253	0.282	NS
PAAD	Pancreatic adenocarcinoma	177	0.48	0.0226	Longer
PCPG	Pheochromocytoma and Paraganglioma	179	652355478.613	0.139	NS
PRAD	Prostate adenocarcinoma	497	1.091	0.915	NS
READ	Rectum adenocarcinoma	159	0.919	0.887	NS
SARC	Sarcoma	259	1.596	0.103	NS
SKCM	Skin Cutaneous Melanoma	459	1.455	0.0418	Shorter
STAD	Stomach adenocarcinoma	388	0.93	0.754	NS
TGCT	Testicular Germ Cell Tumors	134	0.552	0.622	NS
THCA	Thyroid carcinoma	500	0.732	0.67	NS
THYM	Thymoma	119	0.684	0.676	NS
UCEC	Uterine Corpus Endometrial Carcinoma	543	1.764	0.0463	Shorter

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	-0.133	0.00748	Lower
BRCA	Breast invasive carcinoma	1071	-0.042	0.169	NS
CESC	Cervical and endocervical cancers	167	0.023	0.769	NS
COAD	Colon adenocarcinoma	445	0.033	0.491	NS
ESCA	Esophageal carcinoma	162	0.045	0.568	NS
HNSC	Head and Neck squamous cell carcinoma	448	-0.001	0.985	NS
KIRC	Kidney renal clear cell carcinoma	531	-0.03	0.497	NS
KIRP	Kidney renal papillary cell carcinoma	260	-0.057	0.358	NS
LIHC	Liver hepatocellular carcinoma	347	0.054	0.312	NS
LUAD	Lung adenocarcinoma	507	-0.05	0.265	NS
LUSC	Lung squamous cell carcinoma	497	-0.02	0.657	NS
OV	Ovarian serous cystadenocarcinoma	302	-0.099	0.0853	NS
PAAD	Pancreatic adenocarcinoma	176	-0.02	0.793	NS
READ	Rectum adenocarcinoma	156	0.089	0.268	NS
SKCM	Skin Cutaneous Melanoma	410	-0.062	0.214	NS
STAD	Stomach adenocarcinoma	392	0.015	0.77	NS
TGCT	Testicular Germ Cell Tumors	81	-0.369	0.000702	Lower
THCA	Thyroid carcinoma	499	0.002	0.968	NS
UCEC	Uterine Corpus Endometrial Carcinoma	501	0.009	0.841	NS

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	0.004	0.946	NS
HNSC	Head and Neck squamous cell carcinoma	498	0.259	4.57e-09	Higher
KIRC	Kidney renal clear cell carcinoma	525	-0.122	0.00497	Lower
LGG	Brain Lower Grade Glioma	514	-0.074	0.0946	NS
LIHC	Liver hepatocellular carcinoma	366	0.163	0.00172	Higher
OV	Ovarian serous cystadenocarcinoma	296	-0.074	0.202	NS
PAAD	Pancreatic adenocarcinoma	176	-0.088	0.246	NS
STAD	Stomach adenocarcinoma	406	-0.016	0.752	NS
UCEC	Uterine Corpus Endometrial Carcinoma	534	0.003	0.938	NS

Summary
Symbol	POGZ
Name	pogo transposable element derived with ZNF domain
Aliases	KIAA0461; ZNF635m; ZNF280E; zinc finger protein 280E; putative protein product of Nbla00003; MRD37; ZNF635; ......
Location	1q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	POGZ
Name	pogo transposable element derived with ZNF domain
Aliases	KIAA0461; ZNF635m; ZNF280E; zinc finger protein 280E; putative protein product of Nbla00003; MRD37; ZNF635; ......
Location	1q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for POGZ.

Summary
Symbol	POGZ
Name	pogo transposable element derived with ZNF domain
Aliases	KIAA0461; ZNF635m; ZNF280E; zinc finger protein 280E; putative protein product of Nbla00003; MRD37; ZNF635; ......
Location	1q21.3
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining [ TOP ]
There is no record for POGZ.