Browse PPP4R3CP in pancancer

Summary
SymbolPPP4R3CP
Nameprotein phosphatase 4 regulatory subunit 3C, pseudogene
Aliases FLJ32867; FLFL3P; SMEK3P; SMEK homolog 3, suppressor of mek1 (Dictyostelium) pseudogene; Putative SMEK homol ......
LocationXp21.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Domain, Function and Classification
> Gene Ontology
> KEGG and Reactome Pathway
> Domain, Function and Classification
 
Domain PF04802 Component of IIS longevity pathway SMK-1
Function

-

Classification
Class Modification Substrate Product PubMed
# # # # #
> Gene Ontology
 
Biological Process -
Molecular Function -
Cellular Component -
> KEGG and Reactome Pathway
 
KEGG -
Reactome -
Summary
SymbolPPP4R3CP
Nameprotein phosphatase 4 regulatory subunit 3C, pseudogene
Aliases FLJ32867; FLFL3P; SMEK3P; SMEK homolog 3, suppressor of mek1 (Dictyostelium) pseudogene; Putative SMEK homol ......
LocationXp21.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Mutation landscape in primary tumor tissue from TCGA
> Mutation landscape in cancer cell line from CCLE
> All mutations from COSMIC database V81
> Variations from text mining
> The Cancer Genome Atlas (TCGA)
 
There is no record for PPP4R3CP.
> Cancer Cell Line Encyclopedia (CCLE)
 
There is no record.
> Catalogue of Somatic Mutations in Cancer (COSMIC)
 
There is no record for PPP4R3CP.
> Text Mining based Variations
 
There is no record for PPP4R3CP.
Summary
SymbolPPP4R3CP
Nameprotein phosphatase 4 regulatory subunit 3C, pseudogene
Aliases FLJ32867; FLFL3P; SMEK3P; SMEK homolog 3, suppressor of mek1 (Dictyostelium) pseudogene; Putative SMEK homol ......
LocationXp21.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Post-translational modification (PTM)
> Post-translational modification (PTM)
 
There is no PTM data
Summary
SymbolPPP4R3CP
Nameprotein phosphatase 4 regulatory subunit 3C, pseudogene
Aliases FLJ32867; FLFL3P; SMEK3P; SMEK homolog 3, suppressor of mek1 (Dictyostelium) pseudogene; Putative SMEK homol ......
LocationXp21.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Expression analysis in primary tumor tissue from TCGA
> Expression level in cancer cell line from CCLE
> Expression level in human normal tissue from HPA
> Text mining based expression change
> The Cancer Genome Atlas (TCGA)
 


  Differential expression analysis for cancers with more than 10 normal samples
Cancer Full Name # N # T Median (N) Median (T) LogFC Adj. P Status
BLCABladder urothelial carcinoma19408-6.132-6.1330.6940.27NS
LIHCLiver hepatocellular carcinoma50373-6.037-5.782.4484.51e-05Over
LUSCLung squamous cell carcinoma51501-6.869-6.2761.7713.56e-06Over
SKCMSkin Cutaneous Melanoma1472-2.928-6.322NANANA
TGCTTesticular Germ Cell Tumors0156NA-1.285NANANA
> Cancer Cell Line Encyclopedia (CCLE)
 

There is no record.
> The Human Protein Atlas (HPA)
 
There is no HPA expression data.
> Text Mining based Expression
 
There is no record.
Summary
SymbolPPP4R3CP
Nameprotein phosphatase 4 regulatory subunit 3C, pseudogene
Aliases FLJ32867; FLFL3P; SMEK3P; SMEK homolog 3, suppressor of mek1 (Dictyostelium) pseudogene; Putative SMEK homol ......
LocationXp21.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Somatic copy number alteration in primary tomur tissue
> The Cancer Genome Atlas (TCGA)
 
There is no record.
Summary
SymbolPPP4R3CP
Nameprotein phosphatase 4 regulatory subunit 3C, pseudogene
Aliases FLJ32867; FLFL3P; SMEK3P; SMEK homolog 3, suppressor of mek1 (Dictyostelium) pseudogene; Putative SMEK homol ......
LocationXp21.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Methylation level in the promoter region of CR
> Methylation level in the promoter region of CR
 


  Correlation between expression and methylation as well as differential methylation analysis.
Cancer Full Name R P # N # T Delta beta (T vs N) P value (T vs N) Status
BLCABladder urothelial carcinoma-0.3712.59e-1517408-0.1432.66e-22NS/NA
LIHCLiver hepatocellular carcinoma-0.571041373-0.3493.38e-68Decreased
LUSCLung squamous cell carcinoma-0.49708370NANANS/NA
SKCMSkin Cutaneous Melanoma-0.45701471NANANS/NA
TGCTTesticular Germ Cell Tumors-0.800156NANANS/NA
Summary
SymbolPPP4R3CP
Nameprotein phosphatase 4 regulatory subunit 3C, pseudogene
Aliases FLJ32867; FLFL3P; SMEK3P; SMEK homolog 3, suppressor of mek1 (Dictyostelium) pseudogene; Putative SMEK homol ......
LocationXp21.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Primary tumor tissue from TCGA
> Normal tumor tissue from HPA
>The Cancer Genome Atlas (TCGA)
 
There is no record.
> The Human Protein Atlas (HPA)
 
There is no antibody staining data.
Summary
SymbolPPP4R3CP
Nameprotein phosphatase 4 regulatory subunit 3C, pseudogene
Aliases FLJ32867; FLFL3P; SMEK3P; SMEK homolog 3, suppressor of mek1 (Dictyostelium) pseudogene; Putative SMEK homol ......
LocationXp21.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Association between expresson and subtype
> Overall survival analysis based on expression
> Association between expresson and stage
> Association between expresson and grade
> Subtype
 


  Association between expresson and subtype.
Cancer Full Name # Patients P Value (Kruskal-Wallis) Association Source
BLCABladder urothelial carcinoma1280.979NS24476821
LUSCLung squamous cell carcinoma1780.439NS22960745
SKCMSkin Cutaneous Melanoma3150.147NS26091043
> Overall survival
 

  Overall survival analysis based on expression.
Cancer Full Name # Patients Hazard Ratio P Value (Log Rank Test) Association
BLCABladder urothelial carcinoma405 1.2960.224NS
LIHCLiver hepatocellular carcinoma365 1.0270.91NS
LUSCLung squamous cell carcinoma494 0.9370.734NS
SKCMSkin Cutaneous Melanoma459 0.7730.17NS
TGCTTesticular Germ Cell Tumors134 00.165NS
> Stage
 

  Association between expresson and stage.
Cancer Full Name # Patients R Value (Spearman) P Value (Spearman) Association
BLCABladder urothelial carcinoma406 0.0470.347NS
LIHCLiver hepatocellular carcinoma347 -0.0620.252NS
LUSCLung squamous cell carcinoma497 0.0090.833NS
SKCMSkin Cutaneous Melanoma410 0.1030.0375Higher
TGCTTesticular Germ Cell Tumors81 -0.2780.012Lower
> Grade
 

  Association between expresson and grade.
Cancer Full Name # Patients R Value (Spearman) P Value (Spearman) Association
LIHCLiver hepatocellular carcinoma366 -0.0110.831NS
Summary
SymbolPPP4R3CP
Nameprotein phosphatase 4 regulatory subunit 3C, pseudogene
Aliases FLJ32867; FLFL3P; SMEK3P; SMEK homolog 3, suppressor of mek1 (Dictyostelium) pseudogene; Putative SMEK homol ......
LocationXp21.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Targets inferred by reverse engineering method
> Targets identified by ChIP-seq data
> Targets inferred by reverse engineering method
 
> Targets identified by ChIP-seq data
 
Summary
SymbolPPP4R3CP
Nameprotein phosphatase 4 regulatory subunit 3C, pseudogene
Aliases FLJ32867; FLFL3P; SMEK3P; SMEK homolog 3, suppressor of mek1 (Dictyostelium) pseudogene; Putative SMEK homol ......
LocationXp21.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Drugs from DrugBank database
> Drugs from DrugBank database
 
There is no record for PPP4R3CP.
Summary
SymbolPPP4R3CP
Nameprotein phosphatase 4 regulatory subunit 3C, pseudogene
Aliases FLJ32867; FLFL3P; SMEK3P; SMEK homolog 3, suppressor of mek1 (Dictyostelium) pseudogene; Putative SMEK homol ......
LocationXp21.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Protein-Protein Interaction Network
> miRNA Regulatory Relationship
> Interactions from Text Mining
> Protein-Protein Interaction Network
 
> miRNA Regulatory Relationship
 
There is no record for PPP4R3CP.
> Interactions from Text Mining
 
There is no record for PPP4R3CP.