Browse PRDM10 in pancancer

Summary
SymbolPRDM10
NamePR/SET domain 10
Aliases KIAA1231; PFM7; MGC131802; PRDM zinc finger transcription factor; PR-domain family member 7; tristanin; PR d ......
Location11q24.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Domain, Function and Classification
> Gene Ontology
> KEGG and Reactome Pathway
> Domain, Function and Classification
 
Domain PF12171 Zinc-finger double-stranded RNA-binding
Function

May be involved in transcriptional regulation.

Classification
Class Modification Substrate Product PubMed
# # # # #
> Gene Ontology
 
Biological Process GO:0032259 methylation
Molecular Function GO:0008168 methyltransferase activity
GO:0016741 transferase activity, transferring one-carbon groups
Cellular Component -
> KEGG and Reactome Pathway
 
KEGG -
Reactome -
Summary
SymbolPRDM10
NamePR/SET domain 10
Aliases KIAA1231; PFM7; MGC131802; PRDM zinc finger transcription factor; PR-domain family member 7; tristanin; PR d ......
Location11q24.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Mutation landscape in primary tumor tissue from TCGA
> Mutation landscape in cancer cell line from CCLE
> All mutations from COSMIC database V81
> Variations from text mining
> The Cancer Genome Atlas (TCGA)
 
> Cancer Cell Line Encyclopedia (CCLE)
 
There is no record.
> Catalogue of Somatic Mutations in Cancer (COSMIC)
 
COSMIC ID CDS change AA change Mutation Type Anatomical Site
COSM5613320c.1287+2T>Ap.?UnknownLung
COSM3445293c.2439C>Tp.P813PSubstitution - coding silentSkin
COSM924947c.2223C>Tp.H741HSubstitution - coding silentEndometrium
COSM4019326c.1523G>Ap.R508HSubstitution - MissenseStomach
COSM5566554c.1859G>Ap.R620QSubstitution - MissenseProstate
COSM3445294c.2409C>Tp.L803LSubstitution - coding silentSkin
COSM1978018c.1842C>Tp.C614CSubstitution - coding silentLarge_intestine
COSM687270c.2830C>Tp.Q944*Substitution - NonsenseLung
COSM924950c.1894C>Tp.R632CSubstitution - MissenseEndometrium
COSM1978013c.2050C>Tp.R684WSubstitution - MissenseStomach
COSM4717446c.2128A>Gp.K710ESubstitution - MissenseLarge_intestine
COSM1475260c.386G>Tp.R129ISubstitution - MissenseBreast
COSM5901754c.587C>Tp.P196LSubstitution - MissenseSkin
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM3445287c.3269G>Ap.G1090DSubstitution - MissenseSkin
COSM1978045c.862C>Tp.R288WSubstitution - MissenseThyroid
COSM4019323c.3211A>Gp.T1071ASubstitution - MissenseStomach
COSM4574170c.1337C>Tp.A446VSubstitution - MissenseBone
COSM4717442c.2566T>Cp.F856LSubstitution - MissenseLarge_intestine
COSM1978003c.2488G>Ap.V830ISubstitution - MissenseStomach
COSM213347c.941A>Cp.N314TSubstitution - MissenseBreast
COSM1352575c.628delCp.L210fs*5Deletion - FrameshiftLarge_intestine
COSM4639715c.3185C>Tp.T1062MSubstitution - MissenseLarge_intestine
COSM6000164c.1255G>Ap.E419KSubstitution - MissenseProstate
COSM3445294c.2409C>Tp.L803LSubstitution - coding silentSkin
COSM4574169c.3428C>Ap.T1143NSubstitution - MissenseBone
COSM3445295c.1736C>Tp.S579LSubstitution - MissenseSkin
COSM4717443c.2397C>Tp.S799SSubstitution - coding silentLarge_intestine
COSM1352569c.1286A>Gp.Q429RSubstitution - MissenseLarge_intestine
COSM1352570c.1249A>Gp.T417ASubstitution - MissenseLarge_intestine
COSM1352576c.542C>Tp.A181VSubstitution - MissenseLarge_intestine
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM3445301c.561G>Ap.P187PSubstitution - coding silentSkin
COSM6018897c.2598A>Gp.P866PSubstitution - coding silentSkin
COSM3808791c.1393C>Tp.P465SSubstitution - MissenseBreast
COSM203716c.2568C>Tp.F856FSubstitution - coding silentSkin
COSM4480258c.2389C>Tp.P797SSubstitution - MissenseSkin
COSM6000164c.1255G>Ap.E419KSubstitution - MissenseProstate
COSM6000164c.1255G>Ap.E419KSubstitution - MissenseProstate
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM3981396c.721G>Ap.V241ISubstitution - MissenseOvary
COSM5012454c.926A>Gp.Y309CSubstitution - MissenseKidney
COSM5646615c.1501G>Tp.D501YSubstitution - MissenseOesophagus
COSM4961462c.3446G>Ap.S1149NSubstitution - MissenseLiver
COSM4961462c.3446G>Ap.S1149NSubstitution - MissenseLiver
COSM254904c.82C>Gp.P28ASubstitution - MissenseUrinary_tract
COSM203717c.2549G>Ap.R850QSubstitution - MissenseEndometrium
COSM687271c.3315A>Tp.Q1105HSubstitution - MissenseLung
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseBone
COSM924949c.1988C>Tp.S663LSubstitution - MissenseLarge_intestine
COSM1604308c.704C>Tp.P235LSubstitution - MissenseLiver
COSM1352575c.628delCp.L210fs*5Deletion - FrameshiftLarge_intestine
COSM5739510c.2195T>Gp.F732CSubstitution - MissenseSmall_intestine
COSM1492489c.1788T>Cp.L596LSubstitution - coding silentKidney
COSM4607278c.639C>Ap.Y213*Substitution - NonsenseAdrenal_gland
COSM3998334c.1705A>Cp.T569PSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM687267c.1220G>Tp.R407LSubstitution - MissenseLung
COSM4896273c.2849C>Tp.S950FSubstitution - MissenseSkin
COSM254904c.82C>Gp.P28ASubstitution - MissenseUrinary_tract
COSM1726283c.1963C>Ap.L655MSubstitution - MissenseLiver
COSM4610887c.1887delAp.K629fs*101Deletion - FrameshiftLarge_intestine
COSM254905c.427G>Ap.D143NSubstitution - MissenseUrinary_tract
COSM4960802c.2467G>Ap.G823SSubstitution - MissenseLiver
COSM84122c.1895G>Ap.R632HSubstitution - MissensePancreas
COSM1978043c.978C>Tp.A326ASubstitution - coding silentBone
COSM4019327c.1270A>Tp.S424CSubstitution - MissenseStomach
COSM3445300c.570C>Tp.G190GSubstitution - coding silentSkin
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM296782c.2296C>Tp.R766CSubstitution - MissenseStomach
COSM1604307c.2215-6C>Gp.?UnknownLiver
COSM3445294c.2409C>Tp.L803LSubstitution - coding silentSkin
COSM254905c.427G>Ap.D143NSubstitution - MissenseUrinary_tract
COSM4145531c.3370C>Tp.L1124LSubstitution - coding silentThyroid
COSM4019328c.1267A>Gp.K423ESubstitution - MissenseStomach
COSM687265c.868G>Tp.A290SSubstitution - MissenseLung
COSM171638c.2548C>Tp.R850*Substitution - NonsenseEndometrium
COSM428709c.70G>Tp.V24LSubstitution - MissenseBreast
COSM1352563c.2756G>Tp.R919ISubstitution - MissenseLarge_intestine
COSM1241616c.1721A>Tp.H574LSubstitution - MissenseOesophagus
COSM5372041c.2735C>Tp.T912MSubstitution - MissenseSkin
COSM147383c.64G>Ap.A22TSubstitution - MissenseLarge_intestine
COSM218303c.2411G>Ap.R804QSubstitution - MissensePancreas
COSM1977997c.2841G>Ap.S947SSubstitution - coding silentLarge_intestine
COSM401299c.807A>Tp.E269DSubstitution - MissenseLung
COSM5775409c.2854C>Gp.H952DSubstitution - MissenseBreast
COSM5555000c.700G>Cp.G234RSubstitution - MissenseProstate
COSM428708c.127G>Tp.V43FSubstitution - MissenseBreast
COSM3445302c.500C>Tp.P167LSubstitution - MissenseSkin
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseSkin
COSM4574171c.423C>Tp.D141DSubstitution - coding silentBone
COSM4613810c.137_138insCp.Q47fs*59Insertion - FrameshiftLarge_intestine
COSM5716075c.254G>Ap.G85DSubstitution - MissenseSkin
COSM1475261c.200C>Tp.T67MSubstitution - MissenseBreast
COSM4165713c.3G>Tp.M1ISubstitution - MissenseKidney
COSM136870c.607C>Tp.R203WSubstitution - MissenseSkin
COSM1663668c.3406C>Ap.Q1136KSubstitution - MissenseKidney
COSM924940c.3154C>Tp.R1052CSubstitution - MissenseEndometrium
COSM5616503c.3164-6T>Gp.?UnknownLung
COSM3445294c.2409C>Tp.L803LSubstitution - coding silentSkin
COSM924952c.1085G>Ap.R362HSubstitution - MissenseEndometrium
COSM5672016c.1371C>Ap.T457TSubstitution - coding silentSoft_tissue
COSM4422920c.1217_1218insCCGGp.P408fs*19Insertion - FrameshiftKidney
COSM5721858c.170C>Tp.S57FSubstitution - MissenseSkin
COSM5372044c.188G>Tp.G63VSubstitution - MissenseSkin
COSM396367c.1560G>Ap.R520RSubstitution - coding silentLung
COSM924944c.2783C>Tp.S928LSubstitution - MissenseEndometrium
COSM5019018c.3428_3430delCCAp.T1143delTDeletion - In frameUrinary_tract
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM924946c.2290C>Ap.P764TSubstitution - MissenseEndometrium
COSM3935380c.2806C>Tp.Q936*Substitution - NonsenseOesophagus
COSM4717444c.2381C>Tp.A794VSubstitution - MissenseLarge_intestine
COSM4019324c.3194C>Ap.P1065QSubstitution - MissenseStomach
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM4717441c.3369C>Tp.S1123SSubstitution - coding silentLarge_intestine
COSM4717448c.1637G>Ap.R546HSubstitution - MissenseLarge_intestine
COSM924953c.979G>Ap.A327TSubstitution - MissenseEndometrium
COSM687266c.922T>Cp.Y308HSubstitution - MissenseLung
COSM147382c.339T>Cp.S113SSubstitution - coding silentHaematopoietic_and_lymphoid_tissue
COSM3935379c.3375C>Ap.D1125ESubstitution - MissenseOesophagus
COSM924949c.1988C>Tp.S663LSubstitution - MissenseEndometrium
COSM1352562c.2958C>Tp.T986TSubstitution - coding silentLarge_intestine
COSM1221868c.3091C>Tp.Q1031*Substitution - NonsenseLarge_intestine
COSM147383c.64G>Ap.A22TSubstitution - MissenseStomach
COSM5721858c.170C>Tp.S57FSubstitution - MissenseSkin
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM147381c.1287+6G>Cp.?UnknownStomach
COSM1352564c.2487C>Tp.P829PSubstitution - coding silentBone
COSM4187074c.804_806delTGAp.H268_E269>QComplex - deletion inframeKidney
COSM1676583c.2417C>Tp.A806VSubstitution - MissenseLarge_intestine
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM3445292c.2485C>Tp.P829SSubstitution - MissenseSkin
COSM4793770c.3364G>Ap.D1122NSubstitution - MissenseLiver
COSM5433756c.2987C>Gp.S996CSubstitution - MissenseOesophagus
COSM1287363c.3034A>Tp.S1012CSubstitution - MissenseAutonomic_ganglia
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM3808790c.2399T>Cp.I800TSubstitution - MissenseBreast
COSM3981395c.755A>Cp.H252PSubstitution - MissenseOvary
COSM3723183c.2841+1G>Ap.?UnknownUpper_aerodigestive_tract
COSM163705c.997G>Ap.V333MSubstitution - MissenseBreast
COSM3375731c.2823A>Cp.Q941HSubstitution - MissensePancreas
COSM924941c.3125C>Tp.T1042MSubstitution - MissenseLung
COSM4926982c.2027A>Gp.Q676RSubstitution - MissenseLiver
COSM5030270c.1614G>Ap.K538KSubstitution - coding silentBone
COSM5787808c.2080G>Cp.E694QSubstitution - MissenseBreast
COSM466566c.465G>Ap.T155TSubstitution - coding silentCentral_nervous_system
COSM3445299c.720C>Tp.L240LSubstitution - coding silentSkin
COSM3415684c.23C>Tp.S8LSubstitution - MissenseLarge_intestine
COSM4564962c.1565_1566CC>TTp.S522FSubstitution - MissenseSkin
COSM1352571c.1210C>Tp.R404WSubstitution - MissenseLarge_intestine
COSM4543362c.336G>Ap.E112ESubstitution - coding silentSkin
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM466566c.465G>Ap.T155TSubstitution - coding silentStomach
COSM5747346c.209A>Gp.Y70CSubstitution - MissensePancreas
COSM3998335c.1317A>Gp.Q439QSubstitution - coding silentHaematopoietic_and_lymphoid_tissue
COSM5372040c.3079C>Tp.L1027LSubstitution - coding silentSkin
COSM1604308c.704C>Tp.P235LSubstitution - MissenseLiver
COSM5456093c.3355G>Ap.A1119TSubstitution - MissenseLarge_intestine
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM1704822c.2777C>Tp.S926LSubstitution - MissenseSkin
COSM924942c.3103_3105delCAGp.Q1035delQDeletion - In frameEndometrium
COSM5180965c.2787G>Ap.A929ASubstitution - coding silentBiliary_tract
COSM5787785c.2041G>Cp.D681HSubstitution - MissenseBreast
COSM3808792c.1219C>Tp.R407CSubstitution - MissenseBreast
COSM4717447c.2100C>Tp.A700ASubstitution - coding silentCervix
COSM466565c.1050G>Cp.E350DSubstitution - MissenseKidney
COSM3986038c.375C>Tp.T125TSubstitution - coding silentKidney
COSM1352564c.2487C>Tp.P829PSubstitution - coding silentHaematopoietic_and_lymphoid_tissue
COSM3868803c.762+2T>Gp.?UnknownSkin
COSM3445297c.1543C>Tp.Q515*Substitution - NonsenseSkin
COSM3967415c.1571G>Ap.R524QSubstitution - MissenseCentral_nervous_system
COSM1746136c.1735T>Cp.S579PSubstitution - MissenseUrinary_tract
COSM1978050c.677G>Ap.R226HSubstitution - MissenseLarge_intestine
COSM394389c.475G>Tp.D159YSubstitution - MissenseLung
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM1676583c.2417C>Tp.A806VSubstitution - MissenseLarge_intestine
COSM3935380c.2806C>Tp.Q936*Substitution - NonsenseOesophagus
COSM1352564c.2487C>Tp.P829PSubstitution - coding silentHaematopoietic_and_lymphoid_tissue
COSM1297834c.424G>Ap.E142KSubstitution - MissenseUrinary_tract
COSM5716075c.254G>Ap.G85DSubstitution - MissenseSkin
COSM5418956c.220G>Ap.V74MSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM1352567c.1881G>Ap.V627VSubstitution - coding silentLarge_intestine
COSM171638c.2548C>Tp.R850*Substitution - NonsenseLarge_intestine
COSM2157634c.1085_1086insCp.R363fs*16Insertion - FrameshiftCentral_nervous_system
COSM1262939c.1613A>Gp.K538RSubstitution - MissenseStomach
COSM5372043c.1034G>Ap.R345KSubstitution - MissenseSkin
COSM1724619c.1084_1085insCp.R362fs*17Insertion - FrameshiftSkin
COSM218303c.2411G>Ap.R804QSubstitution - MissensePancreas
COSM5820297c.3392A>Gp.Q1131RSubstitution - MissenseLiver
COSM3445288c.3063C>Tp.S1021SSubstitution - coding silentSkin
COSM284217c.790G>Tp.E264*Substitution - NonsenseLarge_intestine
COSM924939c.3457A>Gp.I1153VSubstitution - MissenseEndometrium
COSM3445303c.469C>Tp.L157LSubstitution - coding silentSkin
COSM5349644c.608G>Ap.R203QSubstitution - MissenseLung
COSM3716785c.1157+2T>Cp.?UnknownOesophagus
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM4019325c.2440A>Gp.M814VSubstitution - MissenseStomach
COSM4717450c.296C>Ap.A99DSubstitution - MissenseLarge_intestine
COSM4574171c.423C>Tp.D141DSubstitution - coding silentLarge_intestine
COSM5019018c.3428_3430delCCAp.T1143delTDeletion - In frameSoft_tissue
COSM4717440c.3445A>Gp.S1149GSubstitution - MissenseLarge_intestine
COSM5651861c.2287A>Tp.K763*Substitution - NonsenseHaematopoietic_and_lymphoid_tissue
COSM4189891c.2187G>Cp.M729ISubstitution - MissenseBreast
COSM5602123c.3435G>Ap.G1145GSubstitution - coding silentSkin
COSM4647282c.2547T>Cp.I849ISubstitution - coding silentLarge_intestine
COSM3445298c.1201C>Tp.P401SSubstitution - MissenseSkin
COSM1978013c.2050C>Tp.R684WSubstitution - MissenseLarge_intestine
COSM4481766c.2528C>Tp.T843ISubstitution - MissenseSkin
COSM1352561c.3257C>Tp.A1086VSubstitution - MissenseLarge_intestine
COSM5716075c.254G>Ap.G85DSubstitution - MissenseSkin
COSM924951c.1456C>Tp.Q486*Substitution - NonsenseEndometrium
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM5699709c.3353C>Tp.P1118LSubstitution - MissenseSoft_tissue
COSM3445296c.1605C>Tp.F535FSubstitution - coding silentSkin
COSM1704822c.2777C>Tp.S926LSubstitution - MissenseStomach
COSM4793770c.3364G>Ap.D1122NSubstitution - MissenseLiver
COSM4761290c.2741A>Gp.Q914RSubstitution - MissenseStomach
COSM1352577c.131G>Ap.R44HSubstitution - MissenseLarge_intestine
COSM466566c.465G>Ap.T155TSubstitution - coding silentEndometrium
COSM3967414c.2731C>Tp.R911*Substitution - NonsenseCentral_nervous_system
COSM1604307c.2215-6C>Gp.?UnknownLiver
COSM1978045c.862C>Tp.R288WSubstitution - MissenseBone
COSM1978012c.2058C>Tp.H686HSubstitution - coding silentLarge_intestine
COSM296782c.2296C>Tp.R766CSubstitution - MissenseLarge_intestine
COSM4769273c.2026C>Ap.Q676KSubstitution - MissenseBiliary_tract
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM5990776c.383delGp.G128fs*87Deletion - FrameshiftLiver
COSM4717445c.2229G>Ap.S743SSubstitution - coding silentLarge_intestine
COSM466564c.1834T>Cp.F612LSubstitution - MissenseKidney
COSM4717449c.1490C>Tp.T497MSubstitution - MissenseLarge_intestine
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM1978050c.677G>Ap.R226HSubstitution - MissenseKidney
COSM3359087c.2959G>Cp.A987PSubstitution - MissenseKidney
COSM3445289c.3033C>Tp.L1011LSubstitution - coding silentSkin
COSM3935381c.1561A>Gp.K521ESubstitution - MissenseOesophagus
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM4145532c.2466G>Ap.T822TSubstitution - coding silentThyroid
COSM924953c.979G>Ap.A327TSubstitution - MissenseLarge_intestine
COSM1316757c.3469T>Gp.*1157GNonstop extensionHaematopoietic_and_lymphoid_tissue
COSM6000164c.1255G>Ap.E419KSubstitution - MissenseProstate
COSM378999c.2176C>Tp.R726CSubstitution - MissenseLung
COSM3445294c.2409C>Tp.L803LSubstitution - coding silentSkin
COSM1352560c.3449A>Tp.E1150VSubstitution - MissenseLarge_intestine
COSM3868802c.2967C>Tp.A989ASubstitution - coding silentSkin
COSM3445291c.2852C>Tp.P951LSubstitution - MissenseSkin
COSM1316758c.3466C>Tp.P1156SSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM4773837c.333C>Tp.I111ISubstitution - coding silentStomach
COSM924945c.2766C>Tp.Y922YSubstitution - coding silentEndometrium
COSM5703914c.2788T>Cp.S930PSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM924943c.2964G>Ap.S988SSubstitution - coding silentEndometrium
COSM1352565c.2472C>Tp.T824TSubstitution - coding silentLarge_intestine
COSM924948c.2120A>Cp.K707TSubstitution - MissenseEndometrium
COSM5435786c.1558C>Tp.R520WSubstitution - MissenseOesophagus
COSM254905c.427G>Ap.D143NSubstitution - MissenseUrinary_tract
COSM1977987c.3155G>Ap.R1052HSubstitution - MissenseLarge_intestine
COSM5432726c.3201G>Ap.Q1067QSubstitution - coding silentOesophagus
COSM6000164c.1255G>Ap.E419KSubstitution - MissenseProstate
COSM687269c.2257G>Ap.E753KSubstitution - MissenseLung
COSM3445290c.2940C>Tp.I980ISubstitution - coding silentSkin
COSM5432726c.3201G>Ap.Q1067QSubstitution - coding silentBreast
COSM4543247c.3332G>Ap.G1111DSubstitution - MissenseSkin
COSM1746135c.1736C>Ap.S579*Substitution - NonsenseUrinary_tract
COSM1604306c.2671A>Gp.T891ASubstitution - MissenseLiver
COSM428707c.3227C>Tp.A1076VSubstitution - MissenseBreast
COSM924942c.3103_3105delCAGp.Q1035delQDeletion - In frameEndometrium
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM203727c.543G>Ap.A181ASubstitution - coding silentEndometrium
COSM5721858c.170C>Tp.S57FSubstitution - MissenseSkin
COSM254904c.82C>Gp.P28ASubstitution - MissenseUrinary_tract
COSM1262938c.2254G>Cp.E752QSubstitution - MissenseOesophagus
COSM5372042c.2375C>Tp.P792LSubstitution - MissenseSkin
COSM1316759c.3464A>Gp.K1155RSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM5050674c.2141C>Tp.T714MSubstitution - MissenseStomach
COSM5517174c.2430G>Ap.E810ESubstitution - coding silentBiliary_tract
COSM177325c.3448G>Ap.E1150KSubstitution - MissenseSkin
COSM4717447c.2100C>Tp.A700ASubstitution - coding silentLarge_intestine
COSM3738950c.2061G>Ap.M687ISubstitution - MissenseLiver
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM5714324c.2669T>Cp.V890ASubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM1704821c.2797C>Tp.Q933*Substitution - NonsenseSkin
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM1352573c.857T>Gp.F286CSubstitution - MissenseLarge_intestine
COSM147382c.339T>Cp.S113SSubstitution - coding silentStomach
COSM4960802c.2467G>Ap.G823SSubstitution - MissenseLiver
COSM4590050c.1332A>Cp.E444DSubstitution - MissenseUpper_aerodigestive_tract
COSM1726779c.1075G>Tp.E359*Substitution - NonsenseLiver
COSM5990777c.383_384GC>CAp.G128ASubstitution - MissenseLiver
COSM377128c.367C>Gp.L123VSubstitution - MissenseLung
COSM1352572c.1129C>Tp.H377YSubstitution - MissenseLarge_intestine
COSM5766131c.2072A>Gp.H691RSubstitution - MissenseLarge_intestine
COSM5050673c.3419C>Tp.T1140ISubstitution - MissenseStomach
COSM5437798c.1705A>Gp.T569ASubstitution - MissenseOesophagus
COSM1604306c.2671A>Gp.T891ASubstitution - MissenseLiver
COSM1978006c.2440A>Cp.M814LSubstitution - MissenseLarge_intestine
COSM924941c.3125C>Tp.T1042MSubstitution - MissenseEndometrium
COSM687268c.1467G>Ap.E489ESubstitution - coding silentLung
COSM3782591c.1491G>Ap.T497TSubstitution - coding silentProstate
COSM1352575c.628delCp.L210fs*5Deletion - FrameshiftLarge_intestine
COSM5721858c.170C>Tp.S57FSubstitution - MissenseSkin
COSM3359086c.3294A>Gp.Q1098QSubstitution - coding silentKidney
COSM1977995c.2882T>Cp.V961ASubstitution - MissenseUpper_aerodigestive_tract
COSM203716c.2568C>Tp.F856FSubstitution - coding silentSkin
COSM1978060c.201G>Ap.T67TSubstitution - coding silentLarge_intestine
COSM4019329c.655G>Tp.G219CSubstitution - MissenseStomach
COSM1297833c.2362C>Gp.L788VSubstitution - MissenseUrinary_tract
COSM5505625c.27T>Cp.H9HSubstitution - coding silentBiliary_tract
COSM466566c.465G>Ap.T155TSubstitution - coding silentKidney
COSM5624222c.1181G>Ap.R394QSubstitution - MissenseOesophagus
COSM5716075c.254G>Ap.G85DSubstitution - MissenseSkin
COSM3738949c.2432C>Tp.P811LSubstitution - MissenseLiver
COSM1978062c.179C>Tp.S60LSubstitution - MissenseSkin
> Text Mining based Variations
 
PMID Variation Cancer Evidence
25516889MutationUndifferentiated Pleomorphic SarcomaUsing RNA-Seq, two cases of UPS were found to display novel gene fusions, both involving the transcription factor PRDM10 as the 3' partner and either MED12 or CITED2 as the 5' partner gene.
Summary
SymbolPRDM10
NamePR/SET domain 10
Aliases KIAA1231; PFM7; MGC131802; PRDM zinc finger transcription factor; PR-domain family member 7; tristanin; PR d ......
Location11q24.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Post-translational modification (PTM)
> Post-translational modification (PTM)
 
 Filter By:
Uniprot ID Position Amino Acid Description Upstream Enzyme Affected By Mutation Amino Acid Sequence Variant
Q9NQV6428TPhosphothreonine-NoNone detected
Summary
SymbolPRDM10
NamePR/SET domain 10
Aliases KIAA1231; PFM7; MGC131802; PRDM zinc finger transcription factor; PR-domain family member 7; tristanin; PR d ......
Location11q24.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Expression analysis in primary tumor tissue from TCGA
> Expression level in cancer cell line from CCLE
> Expression level in human normal tissue from HPA
> Text mining based expression change
> The Cancer Genome Atlas (TCGA)
 


  Differential expression analysis for cancers with more than 10 normal samples
Cancer Full Name # N # T Median (N) Median (T) LogFC Adj. P Status
BLCABladder urothelial carcinoma194083.2573.4480.1650.248NS
BRCABreast invasive carcinoma11211003.9033.73-0.1420.00355NS
CESCCervical and endocervical cancers33062.9623.454NANANA
COADColon adenocarcinoma414593.8533.577-0.2945.92e-05NS
ESCAEsophageal carcinoma111854.1664.3910.0370.845NS
GBMGlioblastoma multiforme51664.0973.299NANANA
HNSCHead and Neck squamous cell carcinoma445223.5653.513-0.0850.415NS
KIRCKidney renal clear cell carcinoma725343.4953.401-0.1490.00479NS
KIRPKidney renal papillary cell carcinoma322913.2763.03-0.3010.00179NS
LAMLAcute Myeloid Leukemia0173NA5.102NANANA
LGGBrain Lower Grade Glioma0530NA3.823NANANA
LIHCLiver hepatocellular carcinoma503732.1622.4180.3110.000134NS
LUADLung adenocarcinoma595173.2813.4870.2220.000874NS
LUSCLung squamous cell carcinoma515013.2873.6010.312.06e-06NS
OVOvarian serous cystadenocarcinoma0307NA3.668NANANA
PAADPancreatic adenocarcinoma41793.3553.492NANANA
PCPGPheochromocytoma and Paraganglioma31842.7423.083NANANA
PRADProstate adenocarcinoma524983.4823.7360.2560.000799NS
READRectum adenocarcinoma101673.7883.545-0.1650.337NS
SARCSarcoma22632.5683.122NANANA
SKCMSkin Cutaneous Melanoma14723.4123.2NANANA
STADStomach adenocarcinoma354153.7844.1590.2870.00306NS
TGCTTesticular Germ Cell Tumors0156NA3.53NANANA
THCAThyroid carcinoma595093.5653.405-0.1550.00497NS
THYMThymoma21204.4913.953NANANA
UCECUterine Corpus Endometrial Carcinoma355463.4263.308-0.0940.311NS
> Cancer Cell Line Encyclopedia (CCLE)
 



Tissue Cell Line Expression Level (Microarray)
Autonomic ganglia CHP126 6.4
Autonomic ganglia CHP212 6.3
Autonomic ganglia IMR32 7.2
Autonomic ganglia KELLY 6.2
Autonomic ganglia KPNRTBM1 6.8
Autonomic ganglia KPNSI9S 6.2
Autonomic ganglia KPNYN 6.6
Autonomic ganglia MHHNB11 5.6
Autonomic ganglia NB1 6.2
Autonomic ganglia NH6 6.8
Autonomic ganglia SHSY5Y 6.8
Autonomic ganglia SIMA 6.5
Autonomic ganglia SKNAS 6
Autonomic ganglia SKNBE2 6.9
Autonomic ganglia SKNDZ 6.5
Autonomic ganglia SKNFI 6.6
Autonomic ganglia SKNSH 6.2
Biliary tract HUCCT1 6.3
Biliary tract HUH28 6.5
Biliary tract SNU1079 6.2
Biliary tract SNU1196 6.3
Biliary tract SNU245 7
Biliary tract SNU308 6.5
Biliary tract SNU478 6.4
Bone 143B 6.7
Bone A673 7
Bone CADOES1 6.9
Bone CAL78 6.2
Bone G292CLONEA141B1 6.8
Bone HOS 6.9
Bone HS706T 6.3
Bone HS737T 6.4
Bone HS819T 6.1
Bone HS821T 6.1
Bone HS822T 6
Bone HS863T 6.4
Bone HS870T 6.4
Bone HS888T 6.7
Bone MG63 6.5
Bone MHHES1 8
Bone OUMS27 6.3
Bone RDES 7.6
Bone SJSA1 6.2
Bone SKES1 7.3
Bone SKNMC 7.6
Bone SW1353 6
Bone T173 6.2
Bone TC71 7
Bone U2OS 6.3
Breast AU565 6.9
Breast BT20 7.2
Breast BT474 6.9
Breast BT483 6.8
Breast BT549 6.4
Breast CAL120 6.4
Breast CAL148 6.9
Breast CAL51 6.9
Breast CAL851 6.1
Breast CAMA1 6.6
Breast DU4475 6.7
Breast EFM192A 6.7
Breast EFM19 7.5
Breast EVSAT 7
Breast HCC1143 6.1
Breast HCC1187 7.1
Breast HCC1395 6.2
Breast HCC1419 6.5
Breast HCC1428 6.5
Breast HCC1500 6.5
Breast HCC1569 6.5
Breast HCC1599 6.8
Breast HCC1806 6.2
Breast HCC1937 6.7
Breast HCC1954 6.6
Breast HCC202 6.4
Breast HCC2157 6.5
Breast HCC2218 6.6
Breast HCC38 5.7
Breast HCC70 6.1
Breast HDQP1 5.9
Breast HMC18 6.7
Breast HS274T 6.2
Breast HS281T 6.4
Breast HS343T 6.4
Breast HS578T 6.7
Breast HS606T 6.2
Breast HS739T 6
Breast HS742T 6.2
Breast JIMT1 6.6
Breast KPL1 6.7
Breast MCF7 6.5
Breast MDAMB134VI 6.9
Breast MDAMB157 6
Breast MDAMB175VII 6.3
Breast MDAMB231 6.7
Breast MDAMB361 6.4
Breast MDAMB415 6.5
Breast MDAMB436 6.4
Breast MDAMB453 6.8
Breast MDAMB468 6.7
Breast SKBR3 6.8
Breast T47D 6.7
Breast UACC812 7
Breast UACC893 6.7
Breast YMB1 6.5
Breast ZR751 6.5
Breast ZR7530 6.5
Central nervous system 1321N1 6.4
Central nervous system 42MGBA 6.8
Central nervous system 8MGBA 6
Central nervous system A172 5.9
Central nervous system AM38 6.6
Central nervous system BECKER 6.5
Central nervous system CAS1 6.4
Central nervous system CCFSTTG1 6.4
Central nervous system D283MED 6.7
Central nervous system D341MED 6.7
Central nervous system DAOY 6.3
Central nervous system DBTRG05MG 6.3
Central nervous system DKMG 6.1
Central nervous system GAMG 6.9
Central nervous system GB1 6.3
Central nervous system GI1 6
Central nervous system GMS10 6.5
Central nervous system GOS3 6.2
Central nervous system H4 6.5
Central nervous system HS683 6.8
Central nervous system KALS1 6.5
Central nervous system KG1C 6.7
Central nervous system KNS42 6.7
Central nervous system KNS60 5.5
Central nervous system KNS81 6.2
Central nervous system KS1 6.4
Central nervous system LN18 6.9
Central nervous system LN229 6.6
Central nervous system M059K 6.3
Central nervous system MOGGCCM 6.2
Central nervous system MOGGUVW 6.5
Central nervous system NMCG1 6.3
Central nervous system ONS76 6.2
Central nervous system SF126 6.3
Central nervous system SF295 6.3
Central nervous system SNB19 6.5
Central nervous system SNU1105 6.3
Central nervous system SNU201 6.6
Central nervous system SNU466 6.6
Central nervous system SNU489 6.1
Central nervous system SNU626 6.1
Central nervous system SNU738 6.5
Central nervous system SW1088 6.3
Central nervous system SW1783 6
Central nervous system T98G 6.3
Central nervous system TM31 6.5
Central nervous system U118MG 6.5
Central nervous system U138MG 6.9
Central nervous system U251MG 6.2
Central nervous system U87MG 6.1
Central nervous system YH13 6.7
Central nervous system YKG1 6.7
Endometrium AN3CA 6.3
Endometrium COLO684 6.4
Endometrium EFE184 5.9
Endometrium EN 6.1
Endometrium ESS1 6.4
Endometrium HEC108 6.1
Endometrium HEC151 6.6
Endometrium HEC1A 6.2
Endometrium HEC1B 6.2
Endometrium HEC251 6.8
Endometrium HEC265 6.9
Endometrium HEC50B 6.6
Endometrium HEC59 6.2
Endometrium HEC6 6
Endometrium ISHIKAWAHERAKLIO02ER 6.7
Endometrium JHUEM1 6.9
Endometrium JHUEM2 6.5
Endometrium JHUEM3 6.3
Endometrium KLE 5.5
Endometrium MFE280 6.8
Endometrium MFE296 6.6
Endometrium MFE319 6.6
Endometrium RL952 6.6
Endometrium SNGM 6
Endometrium SNU1077 6
Endometrium SNU685 6
Endometrium TEN 6.4
Haematopoietic and lymphoid 697 6.7
Haematopoietic and lymphoid A3KAW 6.6
Haematopoietic and lymphoid A4FUK 6.6
Haematopoietic and lymphoid ALLSIL 7
Haematopoietic and lymphoid AML193 6.9
Haematopoietic and lymphoid AMO1 6.3
Haematopoietic and lymphoid BCP1 6.9
Haematopoietic and lymphoid BDCM 6.7
Haematopoietic and lymphoid BL41 9.1
Haematopoietic and lymphoid BL70 9.5
Haematopoietic and lymphoid BV173 6.8
Haematopoietic and lymphoid CA46 9.4
Haematopoietic and lymphoid CI1 7.2
Haematopoietic and lymphoid CMK115 7.5
Haematopoietic and lymphoid CMK86 6.9
Haematopoietic and lymphoid CMK 7.1
Haematopoietic and lymphoid CMLT1 6.3
Haematopoietic and lymphoid COLO775 6.1
Haematopoietic and lymphoid DAUDI 8.5
Haematopoietic and lymphoid DB 8
Haematopoietic and lymphoid DEL 6.6
Haematopoietic and lymphoid DND41 7.2
Haematopoietic and lymphoid DOHH2 8.5
Haematopoietic and lymphoid EB1 6.6
Haematopoietic and lymphoid EB2 7.3
Haematopoietic and lymphoid EHEB 6.5
Haematopoietic and lymphoid EJM 6.4
Haematopoietic and lymphoid EM2 6.6
Haematopoietic and lymphoid EOL1 6.9
Haematopoietic and lymphoid F36P 7.3
Haematopoietic and lymphoid GA10 8.1
Haematopoietic and lymphoid GDM1 6.9
Haematopoietic and lymphoid GRANTA519 6.5
Haematopoietic and lymphoid HDLM2 7.3
Haematopoietic and lymphoid HDMYZ 6.5
Haematopoietic and lymphoid HEL9217 7.2
Haematopoietic and lymphoid HEL 6.9
Haematopoietic and lymphoid HH 8.2
Haematopoietic and lymphoid HL60 6.9
Haematopoietic and lymphoid HPBALL 7.2
Haematopoietic and lymphoid HS604T 6.2
Haematopoietic and lymphoid HS611T 6.8
Haematopoietic and lymphoid HS616T 6.2
Haematopoietic and lymphoid HS751T 6.1
Haematopoietic and lymphoid HT 6.8
Haematopoietic and lymphoid HTK 6.5
Haematopoietic and lymphoid HUNS1 6.9
Haematopoietic and lymphoid HUT102 6.5
Haematopoietic and lymphoid HUT78 6.6
Haematopoietic and lymphoid JEKO1 6.5
Haematopoietic and lymphoid JK1 7.6
Haematopoietic and lymphoid JM1 7.1
Haematopoietic and lymphoid JURKAT 6.7
Haematopoietic and lymphoid JURLMK1 6.4
Haematopoietic and lymphoid JVM2 6.4
Haematopoietic and lymphoid JVM3 6.3
Haematopoietic and lymphoid K562 5.7
Haematopoietic and lymphoid KARPAS299 6.3
Haematopoietic and lymphoid KARPAS422 6.7
Haematopoietic and lymphoid KARPAS620 6.7
Haematopoietic and lymphoid KASUMI1 6.7
Haematopoietic and lymphoid KASUMI2 6.8
Haematopoietic and lymphoid KASUMI6 7
Haematopoietic and lymphoid KCL22 6.3
Haematopoietic and lymphoid KE37 6.9
Haematopoietic and lymphoid KE97 6.7
Haematopoietic and lymphoid KG1 7.3
Haematopoietic and lymphoid KHM1B 6.3
Haematopoietic and lymphoid KIJK 6.4
Haematopoietic and lymphoid KMH2 6.4
Haematopoietic and lymphoid KMM1 6.7
Haematopoietic and lymphoid KMS11 6.2
Haematopoietic and lymphoid KMS12BM 6.9
Haematopoietic and lymphoid KMS18 6.3
Haematopoietic and lymphoid KMS20 6.6
Haematopoietic and lymphoid KMS21BM 6.5
Haematopoietic and lymphoid KMS26 5.8
Haematopoietic and lymphoid KMS27 6.5
Haematopoietic and lymphoid KMS28BM 6.5
Haematopoietic and lymphoid KMS34 6.1
Haematopoietic and lymphoid KO52 7.2
Haematopoietic and lymphoid KOPN8 6.7
Haematopoietic and lymphoid KU812 8.6
Haematopoietic and lymphoid KYO1 6.7
Haematopoietic and lymphoid L1236 6.3
Haematopoietic and lymphoid L363 6.5
Haematopoietic and lymphoid L428 6.2
Haematopoietic and lymphoid L540 6.4
Haematopoietic and lymphoid LAMA84 7
Haematopoietic and lymphoid LOUCY 6.8
Haematopoietic and lymphoid LP1 5.9
Haematopoietic and lymphoid M07E 6.6
Haematopoietic and lymphoid MC116 9.4
Haematopoietic and lymphoid ME1 7.1
Haematopoietic and lymphoid MEC1 6.2
Haematopoietic and lymphoid MEC2 7
Haematopoietic and lymphoid MEG01 6.5
Haematopoietic and lymphoid MHHCALL2 6.8
Haematopoietic and lymphoid MHHCALL3 7.1
Haematopoietic and lymphoid MHHCALL4 6.9
Haematopoietic and lymphoid MINO 6.6
Haematopoietic and lymphoid MJ 6.5
Haematopoietic and lymphoid MM1S 6.5
Haematopoietic and lymphoid MOLM13 7.2
Haematopoietic and lymphoid MOLM16 7
Haematopoietic and lymphoid MOLM6 7
Haematopoietic and lymphoid MOLP2 5.9
Haematopoietic and lymphoid MOLP8 6.3
Haematopoietic and lymphoid MOLT13 7
Haematopoietic and lymphoid MOLT16 6.8
Haematopoietic and lymphoid MOLT4 6.9
Haematopoietic and lymphoid MONOMAC1 7.1
Haematopoietic and lymphoid MONOMAC6 7
Haematopoietic and lymphoid MOTN1 6.8
Haematopoietic and lymphoid MUTZ5 7
Haematopoietic and lymphoid MV411 7.1
Haematopoietic and lymphoid NALM19 7
Haematopoietic and lymphoid NALM1 7.1
Haematopoietic and lymphoid NALM6 7.7
Haematopoietic and lymphoid NAMALWA 6.3
Haematopoietic and lymphoid NB4 7.1
Haematopoietic and lymphoid NCIH929 6.4
Haematopoietic and lymphoid NCO2 9.2
Haematopoietic and lymphoid NOMO1 6.8
Haematopoietic and lymphoid NUDHL1 6.9
Haematopoietic and lymphoid NUDUL1 6.6
Haematopoietic and lymphoid OCIAML2 7.1
Haematopoietic and lymphoid OCIAML3 6.6
Haematopoietic and lymphoid OCIAML5 8.6
Haematopoietic and lymphoid OCILY10 6.8
Haematopoietic and lymphoid OCILY19 7.2
Haematopoietic and lymphoid OCILY3 6.6
Haematopoietic and lymphoid OCIM1 6.7
Haematopoietic and lymphoid OPM2 5.5
Haematopoietic and lymphoid P12ICHIKAWA 7.1
Haematopoietic and lymphoid P31FUJ 7.2
Haematopoietic and lymphoid P3HR1 7.8
Haematopoietic and lymphoid PCM6 6.6
Haematopoietic and lymphoid PEER 6.4
Haematopoietic and lymphoid PF382 7.5
Haematopoietic and lymphoid PFEIFFER 8.7
Haematopoietic and lymphoid PL21 6.5
Haematopoietic and lymphoid RAJI 7.4
Haematopoietic and lymphoid RCHACV 7
Haematopoietic and lymphoid REC1 7.2
Haematopoietic and lymphoid REH 6.8
Haematopoietic and lymphoid RI1 6.9
Haematopoietic and lymphoid RL 8.1
Haematopoietic and lymphoid RPMI8226 6.1
Haematopoietic and lymphoid RPMI8402 6.5
Haematopoietic and lymphoid RS411 6.9
Haematopoietic and lymphoid SEM 7.1
Haematopoietic and lymphoid SET2 7.2
Haematopoietic and lymphoid SIGM5 7.4
Haematopoietic and lymphoid SKM1 6.7
Haematopoietic and lymphoid SKMM2 6.5
Haematopoietic and lymphoid SR786 6.4
Haematopoietic and lymphoid ST486 6.9
Haematopoietic and lymphoid SUDHL10 9.1
Haematopoietic and lymphoid SUDHL1 6.3
Haematopoietic and lymphoid SUDHL4 9
Haematopoietic and lymphoid SUDHL5 7.2
Haematopoietic and lymphoid SUDHL6 8.4
Haematopoietic and lymphoid SUDHL8 5.8
Haematopoietic and lymphoid SUPB15 6.8
Haematopoietic and lymphoid SUPHD1 6.1
Haematopoietic and lymphoid SUPM2 5.9
Haematopoietic and lymphoid SUPT11 7.3
Haematopoietic and lymphoid SUPT1 7.1
Haematopoietic and lymphoid TALL1 7.2
Haematopoietic and lymphoid TF1 7.1
Haematopoietic and lymphoid THP1 7
Haematopoietic and lymphoid TO175T 6.3
Haematopoietic and lymphoid TOLEDO 6.9
Haematopoietic and lymphoid U266B1 6.1
Haematopoietic and lymphoid U937 6.6
Haematopoietic and lymphoid UT7 8.4
Haematopoietic and lymphoid WSUDLCL2 7
Kidney 769P 5.9
Kidney 786O 6.1
Kidney A498 6.2
Kidney A704 6.8
Kidney ACHN 5.7
Kidney BFTC909 6.4
Kidney CAKI1 6.1
Kidney CAKI2 5.6
Kidney CAL54 6.5
Kidney KMRC1 6.1
Kidney KMRC20 6.5
Kidney KMRC2 6.1
Kidney KMRC3 5.8
Kidney OSRC2 6.3
Kidney RCC10RGB 6.2
Kidney SNU1272 6.3
Kidney SNU349 5.5
Kidney TUHR10TKB 6.1
Kidney TUHR14TKB 6
Kidney TUHR4TKB 6
Kidney VMRCRCW 6.3
Kidney VMRCRCZ 6
Large intestine C2BBE1 6.6
Large intestine CCK81 6
Large intestine CL11 6.3
Large intestine CL14 6.6
Large intestine CL34 6.5
Large intestine CL40 6.7
Large intestine COLO205 6.7
Large intestine COLO320 7.1
Large intestine COLO678 7.1
Large intestine CW2 6.8
Large intestine DLD1 6.7
Large intestine GP2D 7
Large intestine HCC56 7
Large intestine HCT116 6.7
Large intestine HCT15 6.6
Large intestine HS675T 6.3
Large intestine HS698T 6.3
Large intestine HT115 6.9
Large intestine HT29 7
Large intestine HT55 6.8
Large intestine KM12 6.5
Large intestine LOVO 7.1
Large intestine LS1034 6.7
Large intestine LS123 6.5
Large intestine LS180 6.9
Large intestine LS411N 6.5
Large intestine LS513 6.8
Large intestine MDST8 6.5
Large intestine NCIH508 6.4
Large intestine NCIH716 6.2
Large intestine NCIH747 6.4
Large intestine OUMS23 6.8
Large intestine RCM1 6.4
Large intestine RKO 6.3
Large intestine SKCO1 6.6
Large intestine SNU1040 6.4
Large intestine SNU1197 6.5
Large intestine SNU175 6.6
Large intestine SNU283 6.8
Large intestine SNU407 7.1
Large intestine SNU503 6.2
Large intestine SNU61 7.1
Large intestine SNU81 6.8
Large intestine SNUC1 6.5
Large intestine SNUC2A 6.5
Large intestine SNUC4 7
Large intestine SNUC5 7
Large intestine SW1116 6.8
Large intestine SW1417 6.5
Large intestine SW1463 6.6
Large intestine SW403 6.7
Large intestine SW480 6.4
Large intestine SW48 6
Large intestine SW620 6.6
Large intestine SW837 6.4
Large intestine SW948 6.7
Large intestine T84 6.6
Liver ALEXANDERCELLS 6
Liver C3A 6.5
Liver HEP3B217 6.6
Liver HEPG2 6.5
Liver HLE 6.8
Liver HLF 6.5
Liver HUH1 6.6
Liver HUH6 6.5
Liver HUH7 6.6
Liver JHH1 6.2
Liver JHH2 6
Liver JHH4 6
Liver JHH5 6.8
Liver JHH6 6.8
Liver JHH7 6.5
Liver LI7 6.4
Liver PLCPRF5 6.5
Liver SKHEP1 6.4
Liver SNU182 6
Liver SNU387 6.5
Liver SNU398 6.8
Liver SNU423 6.4
Liver SNU449 6.2
Liver SNU475 6.6
Liver SNU761 6.3
Liver SNU878 5.8
Liver SNU886 6.2
Lung A549 6.4
Lung ABC1 6.5
Lung BEN 6.5
Lung CAL12T 6.6
Lung CALU1 6.3
Lung CALU3 5.9
Lung CALU6 6.4
Lung CHAGOK1 6.1
Lung COLO668 6.8
Lung COLO699 6.6
Lung CORL105 6.3
Lung CORL23 6.8
Lung CORL24 6.5
Lung CORL279 6.6
Lung CORL311 6.7
Lung CORL47 6.5
Lung CORL51 6.7
Lung CORL88 7.7
Lung CORL95 6.5
Lung CPCN 6.9
Lung DMS114 6.4
Lung DMS153 6.7
Lung DMS273 6.2
Lung DMS454 6.5
Lung DMS53 6.7
Lung DMS79 6.9
Lung DV90 6.4
Lung EBC1 7.2
Lung EPLC272H 5.8
Lung HARA 6.1
Lung HCC1171 6.2
Lung HCC1195 5.6
Lung HCC15 6.5
Lung HCC2279 6.3
Lung HCC2935 6.1
Lung HCC33 6.8
Lung HCC366 7.1
Lung HCC4006 6
Lung HCC44 6
Lung HCC78 6.2
Lung HCC827 6.9
Lung HCC95 6.2
Lung HLC1 6.4
Lung HLFA 6.3
Lung HS229T 6.5
Lung HS618T 6.4
Lung IALM 6.5
Lung KNS62 6.2
Lung LC1F 6.2
Lung LC1SQSF 5.9
Lung LCLC103H 5.8
Lung LCLC97TM1 7
Lung LK2 6.6
Lung LOUNH91 6.1
Lung LU65 6.8
Lung LU99 6.4
Lung LUDLU1 6.3
Lung LXF289 6.6
Lung MORCPR 6.3
Lung NCIH1048 6.7
Lung NCIH1092 7.3
Lung NCIH1105 7.5
Lung NCIH1155 6.8
Lung NCIH1184 7.1
Lung NCIH1299 7.1
Lung NCIH1339 7.4
Lung NCIH1341 6.9
Lung NCIH1355 6.6
Lung NCIH1373 6.9
Lung NCIH1385 5.8
Lung NCIH1395 6
Lung NCIH1435 6.6
Lung NCIH1436 6.8
Lung NCIH1437 6.9
Lung NCIH146 6.4
Lung NCIH1563 6.3
Lung NCIH1568 6.4
Lung NCIH1573 7
Lung NCIH1581 7.1
Lung NCIH1618 6.8
Lung NCIH1623 6.7
Lung NCIH1648 6.3
Lung NCIH1650 6.6
Lung NCIH1651 6.2
Lung NCIH1666 6.5
Lung NCIH1693 6.4
Lung NCIH1694 6.4
Lung NCIH1703 6.3
Lung NCIH1734 6
Lung NCIH1755 6.3
Lung NCIH1781 6.6
Lung NCIH1792 6.2
Lung NCIH1793 6.9
Lung NCIH1836 7.7
Lung NCIH1838 6.1
Lung NCIH1869 6.5
Lung NCIH1876 7.5
Lung NCIH1915 6.6
Lung NCIH1930 6.5
Lung NCIH1944 6.6
Lung NCIH1963 6.7
Lung NCIH196 6.1
Lung NCIH1975 6.3
Lung NCIH2009 6.6
Lung NCIH2023 6.2
Lung NCIH2029 7.6
Lung NCIH2030 6.3
Lung NCIH2066 7.2
Lung NCIH2081 7
Lung NCIH2085 6.6
Lung NCIH2087 6.3
Lung NCIH209 6.8
Lung NCIH2106 6.5
Lung NCIH2110 5.8
Lung NCIH211 6.5
Lung NCIH2122 6.3
Lung NCIH2126 7.4
Lung NCIH2141 9.2
Lung NCIH2170 6.5
Lung NCIH2171 7.3
Lung NCIH2172 6.2
Lung NCIH2196 6.8
Lung NCIH2227 6.7
Lung NCIH2228 6.2
Lung NCIH226 6.4
Lung NCIH2286 6.7
Lung NCIH2291 6.3
Lung NCIH2342 6.9
Lung NCIH2347 6.3
Lung NCIH23 6.2
Lung NCIH2405 6.3
Lung NCIH2444 6.6
Lung NCIH292 6.2
Lung NCIH322 6.8
Lung NCIH3255 6
Lung NCIH358 6.8
Lung NCIH441 6.8
Lung NCIH446 6.8
Lung NCIH460 6
Lung NCIH510 6.8
Lung NCIH520 6.5
Lung NCIH522 6.8
Lung NCIH524 6.4
Lung NCIH526 7.3
Lung NCIH596 6.8
Lung NCIH647 6.3
Lung NCIH650 7.3
Lung NCIH661 6
Lung NCIH69 7.2
Lung NCIH727 6.9
Lung NCIH810 6.3
Lung NCIH82 6.4
Lung NCIH838 6.4
Lung NCIH841 6.7
Lung NCIH854 6.8
Lung NCIH889 6.9
Lung PC14 6.2
Lung RERFLCAD1 6.6
Lung RERFLCAD2 5.6
Lung RERFLCAI 6.4
Lung RERFLCKJ 6.5
Lung RERFLCMS 6.2
Lung RERFLCSQ1 5.6
Lung SBC5 6.3
Lung SCLC21H 7.6
Lung SHP77 6
Lung SKLU1 6.2
Lung SKMES1 6.1
Lung SQ1 6
Lung SW1271 6.9
Lung SW1573 6.4
Lung SW900 6.9
Lung VMRCLCD 6.1
Lung VMRCLCP 6
Oesophagus COLO680N 6.4
Oesophagus ECGI10 6.5
Oesophagus KYSE140 6.1
Oesophagus KYSE150 6.3
Oesophagus KYSE180 6.4
Oesophagus KYSE270 5.8
Oesophagus KYSE30 6.2
Oesophagus KYSE410 6.4
Oesophagus KYSE450 4.8
Oesophagus KYSE510 6.4
Oesophagus KYSE520 5.9
Oesophagus KYSE70 6.4
Oesophagus OE19 7
Oesophagus OE33 6.6
Oesophagus TE10 6.2
Oesophagus TE11 6.8
Oesophagus TE14 6.4
Oesophagus TE15 6.2
Oesophagus TE1 5.9
Oesophagus TE4 5.9
Oesophagus TE5 6.2
Oesophagus TE6 6.3
Oesophagus TE8 6.4
Oesophagus TE9 6.6
Oesophagus TT 6.7
Ovary 59M 6.1
Ovary A2780 6.8
Ovary CAOV3 6.1
Ovary CAOV4 6.4
Ovary COLO704 6.5
Ovary COV318 6.3
Ovary COV362 6.2
Ovary COV434 6.5
Ovary COV504 6.5
Ovary COV644 6.1
Ovary EFO21 6.3
Ovary EFO27 6.4
Ovary ES2 6
Ovary FUOV1 6.9
Ovary HEYA8 6.8
Ovary HS571T 6
Ovary IGROV1 6.8
Ovary JHOC5 6.4
Ovary JHOM1 6.6
Ovary JHOM2B 7
Ovary JHOS2 6.7
Ovary JHOS4 6.4
Ovary KURAMOCHI 6.6
Ovary MCAS 6.7
Ovary NIHOVCAR3 6.4
Ovary OAW28 6.1
Ovary OAW42 6.4
Ovary OC314 6.7
Ovary OC316 6.5
Ovary ONCODG1 6.4
Ovary OV56 6.4
Ovary OV7 6.4
Ovary OV90 6.7
Ovary OVCAR4 6.1
Ovary OVCAR8 6.2
Ovary OVISE 6.2
Ovary OVK18 6.5
Ovary OVKATE 6.2
Ovary OVMANA 6.8
Ovary OVSAHO 5.8
Ovary OVTOKO 5.7
Ovary RMGI 5.8
Ovary RMUGS 6.4
Ovary SKOV3 6.5
Ovary SNU119 6.4
Ovary SNU840 6.3
Ovary SNU8 6.1
Ovary TOV112D 7.2
Ovary TOV21G 6.2
Ovary TYKNU 6.9
Pancreas ASPC1 6.4
Pancreas BXPC3 6.8
Pancreas CAPAN1 6.3
Pancreas CAPAN2 6.7
Pancreas CFPAC1 6.7
Pancreas DANG 8
Pancreas HPAC 7.5
Pancreas HPAFII 6.7
Pancreas HS766T 6.8
Pancreas HUPT3 6.1
Pancreas HUPT4 6.7
Pancreas KCIMOH1 6.8
Pancreas KLM1 6.2
Pancreas KP2 6.8
Pancreas KP3 6.5
Pancreas KP4 7
Pancreas L33 6
Pancreas MIAPACA2 6.5
Pancreas PANC0203 6.9
Pancreas PANC0213 7.2
Pancreas PANC0327 6.6
Pancreas PANC0403 6.4
Pancreas PANC0504 7
Pancreas PANC0813 7.6
Pancreas PANC1005 6.8
Pancreas PANC1 6.7
Pancreas PATU8902 6.8
Pancreas PATU8988S 6.9
Pancreas PATU8988T 7.1
Pancreas PK1 6.2
Pancreas PK45H 6.5
Pancreas PK59 6.6
Pancreas PL45 6.9
Pancreas PSN1 7
Pancreas QGP1 6.1
Pancreas SNU213 6.6
Pancreas SNU324 6.9
Pancreas SNU410 6.2
Pancreas SU8686 6.3
Pancreas SUIT2 6.9
Pancreas SW1990 6
Pancreas T3M4 6.9
Pancreas TCCPAN2 5.9
Pancreas YAPC 7.4
Pleura ACCMESO1 6.4
Pleura DM3 6
Pleura ISTMES1 6.6
Pleura ISTMES2 6.7
Pleura JL1 6.3
Pleura MPP89 6.1
Pleura MSTO211H 6.4
Pleura NCIH2052 6.6
Pleura NCIH2452 6.9
Pleura NCIH28 6.6
Prostate 22RV1 7.2
Prostate DU145 6.2
Prostate LNCAPCLONEFGC 6.5
Prostate MDAPCA2B 6.8
Prostate NCIH660 6.5
Prostate PC3 6.5
Prostate VCAP 7.1
Salivary gland A253 6.1
Salivary gland YD15 7
Skin A101D 6.7
Skin A2058 6.4
Skin A375 6.7
Skin C32 7
Skin CHL1 6.1
Skin CJM 6.3
Skin COLO679 6.2
Skin COLO741 6.7
Skin COLO783 6.5
Skin COLO792 5.9
Skin COLO800 6.5
Skin COLO818 6
Skin COLO829 6.7
Skin COLO849 6.6
Skin G361 6.5
Skin GRM 6.3
Skin HMCB 6.5
Skin HS294T 6.5
Skin HS600T 6.2
Skin HS688AT 6.1
Skin HS695T 6.1
Skin HS839T 6.3
Skin HS852T 6.6
Skin HS895T 6.3
Skin HS934T 6.4
Skin HS936T 6.6
Skin HS939T 6.5
Skin HS940T 6.3
Skin HS944T 6
Skin HT144 6.5
Skin IGR1 6.7
Skin IGR37 6.2
Skin IGR39 6.7
Skin IPC298 6.3
Skin K029AX 6.4
Skin LOXIMVI 7.2
Skin MALME3M 5.6
Skin MDAMB435S 6.2
Skin MELHO 6.3
Skin MELJUSO 6
Skin MEWO 6.4
Skin RPMI7951 6.6
Skin RVH421 6.5
Skin SH4 6.6
Skin SKMEL1 6.6
Skin SKMEL24 6.2
Skin SKMEL28 6.1
Skin SKMEL2 5.6
Skin SKMEL30 6.3
Skin SKMEL31 6.2
Skin SKMEL3 6.4
Skin SKMEL5 6
Skin UACC257 6.4
Skin UACC62 6.4
Skin WM115 6.7
Skin WM1799 6.7
Skin WM2664 6.6
Skin WM793 6.6
Skin WM88 6.2
Skin WM983B 6.1
Small intestine HUTU80 7
Soft tissue A204 6.6
Soft tissue G401 6.8
Soft tissue G402 6.7
Soft tissue GCT 7
Soft tissue HS729 6.4
Soft tissue HT1080 7
Soft tissue KYM1 6.9
Soft tissue MESSA 6.8
Soft tissue RD 6.5
Soft tissue RH30 6.1
Soft tissue RH41 6.8
Soft tissue RKN 6.7
Soft tissue S117 6.1
Soft tissue SJRH30 6.6
Soft tissue SKLMS1 7
Soft tissue SKUT1 7.4
Soft tissue TE125T 6
Soft tissue TE159T 6.1
Soft tissue TE441T 7.1
Soft tissue TE617T 6.7
Stomach 2313287 6
Stomach AGS 6.8
Stomach AZ521 6.8
Stomach ECC10 6.9
Stomach ECC12 6.6
Stomach FU97 6.1
Stomach GCIY 6.2
Stomach GSS 8.6
Stomach GSU 6.8
Stomach HGC27 6.4
Stomach HS746T 6.7
Stomach HUG1N 7
Stomach IM95 6.6
Stomach KATOIII 6.4
Stomach KE39 7
Stomach LMSU 6.5
Stomach MKN1 6.4
Stomach MKN45 7
Stomach MKN74 6.1
Stomach MKN7 6.5
Stomach NCCSTCK140 6.4
Stomach NCIN87 6.4
Stomach NUGC2 6
Stomach NUGC3 6.8
Stomach NUGC4 7.1
Stomach OCUM1 7.2
Stomach RERFGC1B 7
Stomach SH10TC 6.1
Stomach SNU16 6.6
Stomach SNU1 7
Stomach SNU216 6.8
Stomach SNU520 7.1
Stomach SNU5 6.8
Stomach SNU601 6.5
Stomach SNU620 6.6
Stomach SNU668 6.3
Stomach SNU719 6.2
Stomach TGBC11TKB 7.5
Thyroid 8305C 6.7
Thyroid 8505C 7
Thyroid BCPAP 6.7
Thyroid BHT101 6.6
Thyroid CAL62 6.9
Thyroid CGTHW1 6.8
Thyroid FTC133 6
Thyroid FTC238 6.3
Thyroid ML1 6
Thyroid SW579 6.4
Thyroid TT2609C02 6.3
Thyroid TT 6.4
Upper aerodigestive tract BHY 7
Upper aerodigestive tract BICR16 6.2
Upper aerodigestive tract BICR18 6.6
Upper aerodigestive tract BICR22 6.4
Upper aerodigestive tract BICR31 5.8
Upper aerodigestive tract BICR56 7
Upper aerodigestive tract BICR6 6.2
Upper aerodigestive tract CAL27 6.3
Upper aerodigestive tract CAL33 6.5
Upper aerodigestive tract DETROIT562 6.2
Upper aerodigestive tract FADU 6.9
Upper aerodigestive tract HS840T 6.4
Upper aerodigestive tract HSC2 6.2
Upper aerodigestive tract HSC3 6.4
Upper aerodigestive tract HSC4 6.2
Upper aerodigestive tract PECAPJ15 6.5
Upper aerodigestive tract PECAPJ34CLONEC12 6.1
Upper aerodigestive tract PECAPJ41CLONED2 6.1
Upper aerodigestive tract PECAPJ49 6.6
Upper aerodigestive tract SCC15 6.5
Upper aerodigestive tract SCC25 6.6
Upper aerodigestive tract SCC4 6.6
Upper aerodigestive tract SCC9 6.7
Upper aerodigestive tract SNU1076 6.4
Upper aerodigestive tract SNU1214 7
Upper aerodigestive tract SNU46 6.9
Upper aerodigestive tract SNU899 6.7
Upper aerodigestive tract YD10B 6.5
Upper aerodigestive tract YD38 7.1
Upper aerodigestive tract YD8 6.1
Urinary tract 5637 6.4
Urinary tract 639V 6.7
Urinary tract 647V 6.3
Urinary tract BC3C 6.6
Urinary tract BFTC905 6.5
Urinary tract CAL29 6.2
Urinary tract HS172T 6.5
Urinary tract HT1197 6.4
Urinary tract HT1376 6.5
Urinary tract J82 6.2
Urinary tract JMSU1 6.7
Urinary tract KMBC2 6.3
Urinary tract KU1919 6.5
Urinary tract RT11284 6.9
Urinary tract RT112 6.6
Urinary tract RT4 6.8
Urinary tract SCABER 5.9
Urinary tract SW1710 6.3
Urinary tract SW780 7
Urinary tract T24 7
Urinary tract TCCSUP 6
Urinary tract UMUC1 6.1
Urinary tract UMUC3 7.1
Urinary tract VMCUB1 6.4
> The Human Protein Atlas (HPA)
 


Tissue Expression Level (TPM)
Adipose tissue 2.5
Adrenal gland 3.1
Appendix 4.3
Bone marrow 5.3
Breast 5.2
Cerebral cortex 4.6
Cervix, uterine 3.6
Colon 3.5
Duodenum 3.5
Endometrium 5.3
Epididymis 3.9
Esophagus 4.4
Fallopian tube 4.3
Gallbladder 4.4
Heart muscle 1.2
Kidney 2.4
Liver 1.4
Lung 4
Lymph node 4.6
Ovary 4.3
Pancreas 0.6
Parathyroid gland 7.4
Placenta 3.8
Prostate 5.2
Rectum 4.4
Salivary gland 1.1
Seminal vesicle 3.6
Skeletal muscle 2
Skin 7.4
Small intestine 4.1
Smooth muscle 3.7
Spleen 4.3
Stomach 3.8
Testis 4.7
Thyroid gland 5.1
Tonsil 3.9
Urinary bladder 3.9
> Text Mining based Expression
 
There is no record.
Summary
SymbolPRDM10
NamePR/SET domain 10
Aliases KIAA1231; PFM7; MGC131802; PRDM zinc finger transcription factor; PR-domain family member 7; tristanin; PR d ......
Location11q24.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Somatic copy number alteration in primary tomur tissue
> The Cancer Genome Atlas (TCGA)
 


  Correlation between expression and SCNA as well as percentage of patients in different status.
Cancer Full Name # Sample R P % Loss % Neutral % Gain Status
BLCABladder urothelial carcinoma4040.1080.030336.451.512.1Loss
BRCABreast invasive carcinoma10750.287.98e-2147.143.59.4Loss
CESCCervical and endocervical cancers2920.3716e-1154.143.22.7Loss
COADColon adenocarcinoma4490.0530.26614.572.612.9Neutral
ESCAEsophageal carcinoma1830.1710.02142.143.214.8Loss
GBMGlioblastoma multiforme1470.2820.00053515.680.34.1Neutral
HNSCHead and Neck squamous cell carcinoma5140.3051.66e-1245.543.610.9Loss
KIRCKidney renal clear cell carcinoma5250.080.06835.5895.5Neutral
KIRPKidney renal papillary cell carcinoma2880.0850.1539.787.23.1Neutral
LAMLAcute Myeloid Leukemia1660.2050.00795094.65.4Neutral
LGGBrain Lower Grade Glioma5130.1530.0005114.979.515.6Neutral
LIHCLiver hepatocellular carcinoma3640.2115e-052568.16.9Neutral
LUADLung adenocarcinoma5120.2555.19e-0922.553.124.4Neutral
LUSCLung squamous cell carcinoma4980.2735.7e-1036.543.420.1Loss
OVOvarian serous cystadenocarcinoma3000.3931.65e-123438.327.7Loss
PAADPancreatic adenocarcinoma1770.2050.0063110.279.110.7Neutral
PCPGPheochromocytoma and Paraganglioma1620.3834.84e-0727.8711.2Neutral
PRADProstate adenocarcinoma4910.2245.13e-075.587.66.9Neutral
READRectum adenocarcinoma1640.0810.320.76415.2Neutral
SARCSarcoma2550.2290.00022346.744.78.6Loss
SKCMSkin Cutaneous Melanoma3670.2681.96e-075439.56.5Loss
STADStomach adenocarcinoma4130.2341.48e-0619.663.416.9Neutral
TGCTTesticular Germ Cell Tumors1500.0450.58881.3180.7Loss
THCAThyroid carcinoma4970.0490.2741.897.21Neutral
THYMThymoma1190.090.3325.992.41.7Neutral
UCECUterine Corpus Endometrial Carcinoma5370.2316.53e-081677.56.5Neutral
Summary
SymbolPRDM10
NamePR/SET domain 10
Aliases KIAA1231; PFM7; MGC131802; PRDM zinc finger transcription factor; PR-domain family member 7; tristanin; PR d ......
Location11q24.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Methylation level in the promoter region of CR
> Methylation level in the promoter region of CR
 


  Correlation between expression and methylation as well as differential methylation analysis.
Cancer Full Name R P # N # T Delta beta (T vs N) P value (T vs N) Status
BLCABladder urothelial carcinoma-0.2396.41e-07174080.0090.403NS/NA
BRCABreast invasive carcinoma-0.2051.25e-0983785-0.131.03e-21NS/NA
CESCCervical and endocervical cancers-0.2613.5e-063306NANANS/NA
COADColon adenocarcinoma-0.1450.010219297-0.0070.272NS/NA
ESCAEsophageal carcinoma-0.2480.0005049185NANANS/NA
GBMGlioblastoma multiforme-0.1120.373164NANANS/NA
HNSCHead and Neck squamous cell carcinoma-0.1792.79e-05205220.0026.95e-07NS/NA
KIRCKidney renal clear cell carcinoma-0.1160.0312243190.0030.00105NS/NA
KIRPKidney renal papillary cell carcinoma-0.1930.000814232750.0066.41e-08NS/NA
LAMLAcute Myeloid Leukemia-0.1610.03640170NANANS/NA
LGGBrain Lower Grade Glioma-0.0550.210530NANANS/NA
LIHCLiver hepatocellular carcinoma-0.1660.00072541373-0.1761.9e-11NS/NA
LUADLung adenocarcinoma-0.1410.00209214560.0060.595NS/NA
LUSCLung squamous cell carcinoma-0.1690.0009938370NANANS/NA
OVOvarian serous cystadenocarcinoma-0.9330.0007509NANANS/NA
PAADPancreatic adenocarcinoma-0.2410.001074179NANANS/NA
PCPGPheochromocytoma and Paraganglioma-0.2210.002413184NANANS/NA
PRADProstate adenocarcinoma-0.3196.06e-1435498-0.2793.47e-11Decreased
READRectum adenocarcinoma-0.2370.017299NANANS/NA
SARCSarcoma-0.1690.005950263NANANS/NA
SKCMSkin Cutaneous Melanoma-0.1799.8e-051471NANANS/NA
STADStomach adenocarcinoma-0.2231.55e-050372NANANS/NA
TGCTTesticular Germ Cell Tumors-0.4012.76e-070156NANANS/NA
THCAThyroid carcinoma-0.1490.00042650509-0.0210.0881NS/NA
THYMThymoma-0.3120.0004952120NANANS/NA
UCECUterine Corpus Endometrial Carcinoma-0.1750.00015834431-0.0030.207NS/NA
Summary
SymbolPRDM10
NamePR/SET domain 10
Aliases KIAA1231; PFM7; MGC131802; PRDM zinc finger transcription factor; PR-domain family member 7; tristanin; PR d ......
Location11q24.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Primary tumor tissue from TCGA
> Normal tumor tissue from HPA
>The Cancer Genome Atlas (TCGA)
 
There is no record.
> The Human Protein Atlas (HPA)
 


Tissue Level Level Name
Adrenal gland 2 Medium
Appendix 2 Medium
Bone marrow 2 Medium
Breast 2 Medium
Bronchus 2 Medium
Caudate 2 Medium
Cerebellum 1 Low
Cerebral cortex 1 Low
Cervix, uterine 2 Medium
Colon 2 Medium
Duodenum 2 Medium
Endometrium 2 Medium
Epididymis 2 Medium
Esophagus 2 Medium
Fallopian tube 2 Medium
Gallbladder 2 Medium
Heart muscle 1 Low
Hippocampus 1 Low
Kidney 2 Medium
Liver 2 Medium
Lung 1 Low
Lymph node 1 Low
Nasopharynx 2 Medium
Oral mucosa 2 Medium
Ovary 2 Medium
Pancreas 2 Medium
Parathyroid gland 2 Medium
Placenta 2 Medium
Prostate 1 Low
Rectum 2 Medium
Salivary gland 1 Low
Seminal vesicle 1 Low
Skeletal muscle 1 Low
Skin 2 Medium
Small intestine 2 Medium
Smooth muscle 2 Medium
Soft tissue 2 Medium
Spleen 0 Not detected
Stomach 2 Medium
Testis 2 Medium
Thyroid gland 2 Medium
Tonsil 2 Medium
Urinary bladder 2 Medium
Vagina 2 Medium
Summary
SymbolPRDM10
NamePR/SET domain 10
Aliases KIAA1231; PFM7; MGC131802; PRDM zinc finger transcription factor; PR-domain family member 7; tristanin; PR d ......
Location11q24.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Association between expresson and subtype
> Overall survival analysis based on expression
> Association between expresson and stage
> Association between expresson and grade
> Subtype
 


  Association between expresson and subtype.
Cancer Full Name # Patients P Value (Kruskal-Wallis) Association Source
BLCABladder urothelial carcinoma1280.0502NS24476821
BRCABreast invasive carcinoma5211.26e-05Significant23000897
COADColon adenocarcinoma1490.317NS22810696
GBMGlioblastoma multiforme1570.00172Significant26824661
HNSCHead and Neck squamous cell carcinoma2790.0402Significant25631445
KIRPKidney renal papillary cell carcinoma1610.201NS26536169
LGGBrain Lower Grade Glioma5134.01e-14Significant26824661
LUADLung adenocarcinoma2300.139NS25079552
LUSCLung squamous cell carcinoma1780.0788NS22960745
OVOvarian serous cystadenocarcinoma2870.129NS21720365
PRADProstate adenocarcinoma3330.373NS26544944
READRectum adenocarcinoma670.627NS22810696
SKCMSkin Cutaneous Melanoma3150.00893Significant26091043
STADStomach adenocarcinoma2771.66e-05Significant25079317
THCAThyroid carcinoma3910.838NS25417114
UCECUterine Corpus Endometrial Carcinoma2320.0487Significant23636398
> Overall survival
 

  Overall survival analysis based on expression.
Cancer Full Name # Patients Hazard Ratio P Value (Log Rank Test) Association
BLCABladder urothelial carcinoma405 0.8260.364NS
BRCABreast invasive carcinoma1079 1.7830.0118Shorter
CESCCervical and endocervical cancers291 1.1350.712NS
COADColon adenocarcinoma439 0.9360.823NS
ESCAEsophageal carcinoma184 0.6190.125NS
GBMGlioblastoma multiforme158 0.7740.302NS
HNSCHead and Neck squamous cell carcinoma518 0.6310.0242Longer
KIRCKidney renal clear cell carcinoma531 0.5810.0167Longer
KIRPKidney renal papillary cell carcinoma287 1.5360.329NS
LAMLAcute Myeloid Leukemia149 0.9270.804NS
LGGBrain Lower Grade Glioma511 0.3990.000488Longer
LIHCLiver hepatocellular carcinoma365 0.9760.925NS
LUADLung adenocarcinoma502 1.1710.448NS
LUSCLung squamous cell carcinoma494 1.2890.21NS
OVOvarian serous cystadenocarcinoma303 1.110.63NS
PAADPancreatic adenocarcinoma177 1.4080.249NS
PCPGPheochromocytoma and Paraganglioma179 3.6290.232NS
PRADProstate adenocarcinoma497 5.6220.109NS
READRectum adenocarcinoma159 0.4340.139NS
SARCSarcoma259 1.6570.0778NS
SKCMSkin Cutaneous Melanoma459 0.9480.781NS
STADStomach adenocarcinoma388 0.6090.0294Longer
TGCTTesticular Germ Cell Tumors134 1.1330.929NS
THCAThyroid carcinoma500 2.3660.2NS
THYMThymoma119 0.5520.41NS
UCECUterine Corpus Endometrial Carcinoma543 0.9680.916NS
> Stage
 

  Association between expresson and stage.
Cancer Full Name # Patients R Value (Spearman) P Value (Spearman) Association
BLCABladder urothelial carcinoma406 -0.1340.0067Lower
BRCABreast invasive carcinoma1071 -0.030.326NS
CESCCervical and endocervical cancers167 0.1140.142NS
COADColon adenocarcinoma445 -0.060.203NS
ESCAEsophageal carcinoma162 -0.2020.00995Lower
HNSCHead and Neck squamous cell carcinoma448 -0.0330.481NS
KIRCKidney renal clear cell carcinoma531 -0.1030.0173Lower
KIRPKidney renal papillary cell carcinoma260 0.0890.155NS
LIHCLiver hepatocellular carcinoma347 0.040.46NS
LUADLung adenocarcinoma507 0.0460.305NS
LUSCLung squamous cell carcinoma497 0.0360.417NS
OVOvarian serous cystadenocarcinoma302 -0.0420.471NS
PAADPancreatic adenocarcinoma176 0.0190.804NS
READRectum adenocarcinoma156 0.0480.549NS
SKCMSkin Cutaneous Melanoma410 -0.0870.0798NS
STADStomach adenocarcinoma392 0.0040.93NS
TGCTTesticular Germ Cell Tumors81 -0.1430.202NS
THCAThyroid carcinoma499 -0.0750.0933NS
UCECUterine Corpus Endometrial Carcinoma501 -0.0580.197NS
> Grade
 

  Association between expresson and grade.
Cancer Full Name # Patients R Value (Spearman) P Value (Spearman) Association
CESCCervical and endocervical cancers272 -0.1240.0408Lower
HNSCHead and Neck squamous cell carcinoma498 -0.0630.163NS
KIRCKidney renal clear cell carcinoma525 -0.1110.011Lower
LGGBrain Lower Grade Glioma514 -0.0790.0727NS
LIHCLiver hepatocellular carcinoma366 0.1470.0049Higher
OVOvarian serous cystadenocarcinoma296 0.0750.201NS
PAADPancreatic adenocarcinoma176 0.0290.704NS
STADStomach adenocarcinoma406 -0.0870.0798NS
UCECUterine Corpus Endometrial Carcinoma534 0.0030.936NS
Summary
SymbolPRDM10
NamePR/SET domain 10
Aliases KIAA1231; PFM7; MGC131802; PRDM zinc finger transcription factor; PR-domain family member 7; tristanin; PR d ......
Location11q24.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Targets inferred by reverse engineering method
> Targets identified by ChIP-seq data
> Targets inferred by reverse engineering method
 
> Targets identified by ChIP-seq data
 
Summary
SymbolPRDM10
NamePR/SET domain 10
Aliases KIAA1231; PFM7; MGC131802; PRDM zinc finger transcription factor; PR-domain family member 7; tristanin; PR d ......
Location11q24.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Drugs from DrugBank database
> Drugs from DrugBank database
 
There is no record for PRDM10.
Summary
SymbolPRDM10
NamePR/SET domain 10
Aliases KIAA1231; PFM7; MGC131802; PRDM zinc finger transcription factor; PR-domain family member 7; tristanin; PR d ......
Location11q24.3
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Protein-Protein Interaction Network
> miRNA Regulatory Relationship
> Interactions from Text Mining
> Protein-Protein Interaction Network
 
> miRNA Regulatory Relationship
 
> Interactions from Text Mining
 
PMID Cancer Hierarchy Gene Relation to CR Evidence
25516889Undifferentiated Pleomorphic SarcomapartnerMED12FusionFurther screening of 82 soft tissue sarcomas for rearrangements of the PRDM10 locus revealed one more UPS with a MED12/PRDM10 fusion.