Summary | |
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Symbol | PRDM2 |
Name | PR/SET domain 2 |
Aliases | RIZ; RIZ1; RIZ2; KMT8; MTB-ZF; HUMHOXY1; retinoblastoma protein-binding zinc finger protein; retinoblastoma ...... |
Location | 1p36.21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway |
Domain |
PF00856 SET domain |
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Function |
S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene. |
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Classification |
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Biological Process |
GO:0006479 protein methylation GO:0007568 aging GO:0008213 protein alkylation GO:0008340 determination of adult lifespan GO:0010259 multicellular organism aging GO:0016570 histone modification GO:0016571 histone methylation GO:0018022 peptidyl-lysine methylation GO:0018205 peptidyl-lysine modification GO:0032259 methylation GO:0034968 histone lysine methylation GO:0043414 macromolecule methylation |
Molecular Function |
GO:0008168 methyltransferase activity GO:0008170 N-methyltransferase activity GO:0008276 protein methyltransferase activity GO:0008757 S-adenosylmethionine-dependent methyltransferase activity GO:0016278 lysine N-methyltransferase activity GO:0016279 protein-lysine N-methyltransferase activity GO:0016741 transferase activity, transferring one-carbon groups GO:0018024 histone-lysine N-methyltransferase activity GO:0042054 histone methyltransferase activity |
Cellular Component | - |
KEGG |
hsa00310 Lysine degradation |
Reactome | - |
Summary | |
---|---|
Symbol | PRDM2 |
Name | PR/SET domain 2 |
Aliases | RIZ; RIZ1; RIZ2; KMT8; MTB-ZF; HUMHOXY1; retinoblastoma protein-binding zinc finger protein; retinoblastoma ...... |
Location | 1p36.21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining |
There is no record. |
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Summary | |
---|---|
Symbol | PRDM2 |
Name | PR/SET domain 2 |
Aliases | RIZ; RIZ1; RIZ2; KMT8; MTB-ZF; HUMHOXY1; retinoblastoma protein-binding zinc finger protein; retinoblastoma ...... |
Location | 1p36.21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Post-translational modification (PTM) |
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Summary | |
---|---|
Symbol | PRDM2 |
Name | PR/SET domain 2 |
Aliases | RIZ; RIZ1; RIZ2; KMT8; MTB-ZF; HUMHOXY1; retinoblastoma protein-binding zinc finger protein; retinoblastoma ...... |
Location | 1p36.21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change |
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Summary | |
---|---|
Symbol | PRDM2 |
Name | PR/SET domain 2 |
Aliases | RIZ; RIZ1; RIZ2; KMT8; MTB-ZF; HUMHOXY1; retinoblastoma protein-binding zinc finger protein; retinoblastoma ...... |
Location | 1p36.21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Somatic copy number alteration in primary tomur tissue |
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Summary | |
---|---|
Symbol | PRDM2 |
Name | PR/SET domain 2 |
Aliases | RIZ; RIZ1; RIZ2; KMT8; MTB-ZF; HUMHOXY1; retinoblastoma protein-binding zinc finger protein; retinoblastoma ...... |
Location | 1p36.21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Methylation level in the promoter region of CR |
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Summary | |
---|---|
Symbol | PRDM2 |
Name | PR/SET domain 2 |
Aliases | RIZ; RIZ1; RIZ2; KMT8; MTB-ZF; HUMHOXY1; retinoblastoma protein-binding zinc finger protein; retinoblastoma ...... |
Location | 1p36.21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Primary tumor tissue from TCGA > Normal tumor tissue from HPA |
There is no record. |
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Summary | |
---|---|
Symbol | PRDM2 |
Name | PR/SET domain 2 |
Aliases | RIZ; RIZ1; RIZ2; KMT8; MTB-ZF; HUMHOXY1; retinoblastoma protein-binding zinc finger protein; retinoblastoma ...... |
Location | 1p36.21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade |
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Showing 1 to 9 of 9 rows |
Summary | |
---|---|
Symbol | PRDM2 |
Name | PR/SET domain 2 |
Aliases | RIZ; RIZ1; RIZ2; KMT8; MTB-ZF; HUMHOXY1; retinoblastoma protein-binding zinc finger protein; retinoblastoma ...... |
Location | 1p36.21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data |
Summary | |
---|---|
Symbol | PRDM2 |
Name | PR/SET domain 2 |
Aliases | RIZ; RIZ1; RIZ2; KMT8; MTB-ZF; HUMHOXY1; retinoblastoma protein-binding zinc finger protein; retinoblastoma ...... |
Location | 1p36.21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Drugs from DrugBank database |
There is no record for PRDM2. |
Summary | |
---|---|
Symbol | PRDM2 |
Name | PR/SET domain 2 |
Aliases | RIZ; RIZ1; RIZ2; KMT8; MTB-ZF; HUMHOXY1; retinoblastoma protein-binding zinc finger protein; retinoblastoma ...... |
Location | 1p36.21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining |
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