CR2Cancer

Summary
Symbol	PRDM9
Name	PR/SET domain 9
Aliases	PFM6; ZNF899; PR-domain containing protein 9; MSBP3; minisatellite binding protein 3, 115kDa; minisatellite ......
Location	5p14.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

[ TOP ]

Domain

PF01352 KRAB box
PF00856 SET domain
PF09514 SSXRD motif

Function

Histone methyltransferase that specifically trimethylates 'Lys-4' of histone H3 during meiotic prophase and is essential for proper meiotic progression. Does not have the ability to mono- and dimethylate 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes during early meiotic prophase (By similarity).

Classification

Class	Modification	Substrate	Product	PubMed
Histone modification write	Histone methylation	H3K4	H3K4me3	17916234

> Gene Ontology [ TOP ]
Biological Process	GO:0000018 regulation of DNA recombination GO:0006310 DNA recombination GO:0006311 meiotic gene conversion GO:0006479 protein methylation GO:0007126 meiotic nuclear division GO:0007127 meiosis I GO:0007131 reciprocal meiotic recombination GO:0008213 protein alkylation GO:0010520 regulation of reciprocal meiotic recombination GO:0010845 positive regulation of reciprocal meiotic recombination GO:0016570 histone modification GO:0016571 histone methylation GO:0018022 peptidyl-lysine methylation GO:0018205 peptidyl-lysine modification GO:0032259 methylation GO:0034968 histone lysine methylation GO:0035822 gene conversion GO:0035825 reciprocal DNA recombination GO:0040020 regulation of meiotic nuclear division GO:0043414 macromolecule methylation GO:0045787 positive regulation of cell cycle GO:0045836 positive regulation of meiotic nuclear division GO:0045911 positive regulation of DNA recombination GO:0051052 regulation of DNA metabolic process GO:0051054 positive regulation of DNA metabolic process GO:0051321 meiotic cell cycle GO:0051445 regulation of meiotic cell cycle GO:0051446 positive regulation of meiotic cell cycle GO:0051783 regulation of nuclear division GO:0051785 positive regulation of nuclear division GO:0060631 regulation of meiosis I GO:0060903 positive regulation of meiosis I GO:0090068 positive regulation of cell cycle process GO:1903046 meiotic cell cycle process GO:2000241 regulation of reproductive process GO:2000243 positive regulation of reproductive process
Molecular Function	GO:0008168 methyltransferase activity GO:0008170 N-methyltransferase activity GO:0008276 protein methyltransferase activity GO:0008757 S-adenosylmethionine-dependent methyltransferase activity GO:0016278 lysine N-methyltransferase activity GO:0016279 protein-lysine N-methyltransferase activity GO:0016741 transferase activity, transferring one-carbon groups GO:0018024 histone-lysine N-methyltransferase activity GO:0042054 histone methyltransferase activity
Cellular Component	-

> KEGG and Reactome Pathway [ TOP ]
KEGG	hsa00310 Lysine degradation
Reactome	R-HSA-1640170: Cell Cycle R-HSA-3247509: Chromatin modifying enzymes R-HSA-4839726: Chromatin organization R-HSA-1500620: Meiosis R-HSA-912446: Meiotic recombination R-HSA-3214841: PKMTs methylate histone lysines

Summary
Symbol	PRDM9
Name	PR/SET domain 9
Aliases	PFM6; ZNF899; PR-domain containing protein 9; MSBP3; minisatellite binding protein 3, 115kDa; minisatellite ......
Location	5p14.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM1311072	c.494C>G	p.S165*	Substitution - Nonsense	Urinary_tract
COSM3429360	c.102C>T	p.Y34Y	Substitution - coding silent	Large_intestine
COSM3919885	c.277G>A	p.E93K	Substitution - Missense	Skin
COSM3854567	c.790G>C	p.A264P	Substitution - Missense	Stomach
COSM3615201	c.728C>T	p.P243L	Substitution - Missense	Skin
COSM4852554	c.137G>A	p.W46*	Substitution - Nonsense	Cervix
COSM393712	c.2275G>A	p.D759N	Substitution - Missense	Kidney
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM3947400	c.2058C>A	p.H686Q	Substitution - Missense	Lung
COSM4536719	c.2337G>A	p.R779R	Substitution - coding silent	Skin
COSM3854559	c.5G>A	p.S2N	Substitution - Missense	Stomach
COSM296120	c.1855C>T	p.R619W	Substitution - Missense	Cervix
COSM1319205	c.1589G>A	p.G530E	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1436895	c.2664C>T	p.Y888Y	Substitution - coding silent	Central_nervous_system
COSM3013881	c.2524C>T	p.R842C	Substitution - Missense	Thyroid
COSM1067094	c.2496T>C	p.Y832Y	Substitution - coding silent	Thyroid
COSM364651	c.19C>A	p.Q7K	Substitution - Missense	Lung
COSM5356703	c.1644G>A	p.G548G	Substitution - coding silent	Large_intestine
COSM3919891	c.1840G>A	p.G614R	Substitution - Missense	Skin
COSM1328855	c.121G>A	p.A41T	Substitution - Missense	Ovary
COSM125569	c.1398G>T	p.R466S	Substitution - Missense	Upper_aerodigestive_tract
COSM317905	c.1432A>C	p.S478R	Substitution - Missense	Lung
COSM1067061	c.280G>T	p.E94*	Substitution - Nonsense	Endometrium
COSM4513302	c.932C>T	p.S311F	Substitution - Missense	Skin
COSM2155191	c.939C>A	p.A313A	Substitution - coding silent	Central_nervous_system
COSM1067062	c.366G>T	p.A122A	Substitution - coding silent	Endometrium
COSM166748	c.2295A>T	p.R765S	Substitution - Missense	Large_intestine
COSM3615199	c.663C>T	p.P221P	Substitution - coding silent	Skin
COSM226979	c.2440A>C	p.S814R	Substitution - Missense	Skin
COSM1067079	c.1222G>A	p.E408K	Substitution - Missense	Endometrium
COSM4396242	c.2485G>A	p.E829K	Substitution - Missense	Skin
COSM1067094	c.2496T>C	p.Y832Y	Substitution - coding silent	Endometrium
COSM5046829	c.1469G>T	p.G490V	Substitution - Missense	Oesophagus
COSM738270	c.2241C>A	p.P747P	Substitution - coding silent	Lung
COSM132751	c.967C>T	p.R323W	Substitution - Missense	Central_nervous_system
COSM1486703	c.2126C>G	p.T709S	Substitution - Missense	Central_nervous_system
COSM4480773	c.2450C>T	p.S817L	Substitution - Missense	Skin
COSM1642724	c.1713G>A	p.Q571Q	Substitution - coding silent	Stomach
COSM263091	c.1365G>T	p.E455D	Substitution - Missense	Lung
COSM1067088	c.1758G>T	p.G586G	Substitution - coding silent	Endometrium
COSM121633	c.1050C>T	p.G350G	Substitution - coding silent	Upper_aerodigestive_tract
COSM125568	c.953A>T	p.Y318F	Substitution - Missense	Upper_aerodigestive_tract
COSM314413	c.2290C>T	p.L764F	Substitution - Missense	Soft_tissue
COSM4407051	c.2276A>G	p.D759G	Substitution - Missense	Liver
COSM3013853	c.2188A>C	p.S730R	Substitution - Missense	Thyroid
COSM3410220	c.1717A>T	p.I573L	Substitution - Missense	Central_nervous_system
COSM314414	c.1675C>A	p.R559R	Substitution - coding silent	Lung
COSM1067076	c.914T>A	p.V305E	Substitution - Missense	Endometrium
COSM1067067	c.551G>A	p.R184Q	Substitution - Missense	Endometrium
COSM4977024	c.1279C>T	p.P427S	Substitution - Missense	Oesophagus
COSM1311077	c.1970G>C	p.R657T	Substitution - Missense	Bone
COSM1567726	c.2190C>A	p.S730R	Substitution - Missense	Oesophagus
COSM3615188	c.230G>A	p.R77Q	Substitution - Missense	Cervix
COSM1486702	c.2075A>G	p.Y692C	Substitution - Missense	Breast
COSM5047520	c.2333G>C	p.C778S	Substitution - Missense	Oesophagus
COSM3615197	c.579G>A	p.E193E	Substitution - coding silent	Skin
COSM4717528	c.2175T>A	p.C725*	Substitution - Nonsense	Large_intestine
COSM5912337	c.301+5G>A	p.?	Unknown	Skin
COSM119903	c.796G>A	p.D266N	Substitution - Missense	Ovary
COSM1311076	c.1886G>C	p.R629T	Substitution - Missense	Skin
COSM3697199	c.1676G>T	p.R559L	Substitution - Missense	Large_intestine
COSM1067093	c.2379T>A	p.S793R	Substitution - Missense	Prostate
COSM5438194	c.385A>G	p.S129G	Substitution - Missense	Oesophagus
COSM3697198	c.1033C>T	p.R345*	Substitution - Nonsense	Large_intestine
COSM322806	c.2627G>C	p.C876S	Substitution - Missense	Lung
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM3615194	c.509-1G>A	p.?	Unknown	Skin
COSM1067096	c.2564C>A	p.T855K	Substitution - Missense	Endometrium
COSM222053	c.1119G>A	p.W373*	Substitution - Nonsense	Skin
COSM1292117	c.727C>A	p.P243T	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5630384	c.1711C>A	p.Q571K	Substitution - Missense	Oesophagus
COSM1436885	c.1340G>A	p.R447H	Substitution - Missense	Large_intestine
COSM1436895	c.2664C>T	p.Y888Y	Substitution - coding silent	Large_intestine
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM3615193	c.467G>A	p.G156E	Substitution - Missense	Skin
COSM226129	c.2358A>C	p.R786S	Substitution - Missense	Breast
COSM4605602	c.553G>A	p.E185K	Substitution - Missense	Upper_aerodigestive_tract
COSM5045425	c.5G>T	p.S2I	Substitution - Missense	Oesophagus
COSM1067075	c.909G>T	p.E303D	Substitution - Missense	Endometrium
COSM125571	c.2273G>A	p.R758H	Substitution - Missense	Pancreas
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM3615188	c.230G>A	p.R77Q	Substitution - Missense	Skin
COSM4159840	c.2191A>G	p.N731D	Substitution - Missense	Large_intestine
COSM5724750	c.268G>A	p.D90N	Substitution - Missense	Skin
COSM5947046	c.952T>C	p.Y318H	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3947394	c.1131C>A	p.L377L	Substitution - coding silent	Lung
COSM1067094	c.2496T>C	p.Y832Y	Substitution - coding silent	Large_intestine
COSM3615209	c.1288C>T	p.P430S	Substitution - Missense	Skin
COSM3919889	c.844G>A	p.E282K	Substitution - Missense	Skin
COSM3615226	c.2505G>A	p.R835R	Substitution - coding silent	Skin
COSM317905	c.1432A>C	p.S478R	Substitution - Missense	Soft_tissue
COSM1067091	c.2235G>T	p.E745D	Substitution - Missense	Endometrium
COSM1221906	c.44C>T	p.T15I	Substitution - Missense	Large_intestine
COSM1067087	c.1686C>A	p.S562R	Substitution - Missense	Endometrium
COSM4400253	c.1248C>T	p.F416F	Substitution - coding silent	Skin
COSM5666695	c.2399G>A	p.G800E	Substitution - Missense	Soft_tissue
COSM1436879	c.638T>C	p.I213T	Substitution - Missense	Large_intestine
COSM4495785	c.460C>T	p.P154S	Substitution - Missense	Skin
COSM3854571	c.1515T>C	p.N505N	Substitution - coding silent	Stomach
COSM4467695	c.1503C>A	p.G501G	Substitution - coding silent	Skin
COSM364004	c.967C>A	p.R323R	Substitution - coding silent	Lung
COSM145810	c.920G>A	p.G307E	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM391684	c.1801_1802delAC	p.T603fs*15	Deletion - Frameshift	Lung
COSM1436884	c.1315C>T	p.Q439*	Substitution - Nonsense	Stomach
COSM145810	c.920G>A	p.G307E	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM389521	c.2184C>A	p.G728G	Substitution - coding silent	Lung
COSM231055	c.1790C>G	p.T597S	Substitution - Missense	Skin
COSM5021466	c.2054C>T	p.T685I	Substitution - Missense	Bone
COSM1067085	c.1413G>T	p.E471D	Substitution - Missense	Endometrium
COSM3615220	c.1813G>A	p.E605K	Substitution - Missense	Skin
COSM3615230	c.2661C>T	p.P887P	Substitution - coding silent	Skin
COSM1221905	c.696G>T	p.K232N	Substitution - Missense	Large_intestine
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM1486703	c.2126C>G	p.T709S	Substitution - Missense	Thyroid
COSM231055	c.1790C>G	p.T597S	Substitution - Missense	Prostate
COSM5628121	c.2524C>A	p.R842S	Substitution - Missense	Oesophagus
COSM1311076	c.1886G>C	p.R629T	Substitution - Missense	Urinary_tract
COSM5556671	c.1792C>T	p.H598Y	Substitution - Missense	Prostate
COSM4460446	c.1166C>T	p.P389L	Substitution - Missense	Liver
COSM338355	c.1068G>T	p.W356C	Substitution - Missense	Lung
COSM1287369	c.209G>T	p.R70L	Substitution - Missense	Autonomic_ganglia
COSM3919892	c.2054C>G	p.T685R	Substitution - Missense	Bone
COSM3615186	c.133G>A	p.D45N	Substitution - Missense	Skin
COSM3947399	c.1976C>T	p.T659I	Substitution - Missense	Lung
COSM1067059	c.249C>T	p.L83L	Substitution - coding silent	Skin
COSM5629598	c.2127T>A	p.T709T	Substitution - coding silent	Large_intestine
COSM3854568	c.970G>A	p.D324N	Substitution - Missense	Stomach
COSM5673748	c.1033C>G	p.R345G	Substitution - Missense	Soft_tissue
COSM1311077	c.1970G>C	p.R657T	Substitution - Missense	Urinary_tract
COSM1067058	c.171C>A	p.N57K	Substitution - Missense	Endometrium
COSM1262962	c.475A>C	p.S159R	Substitution - Missense	Oesophagus
COSM3854576	c.2370C>A	p.N790K	Substitution - Missense	Stomach
COSM4988134	c.904T>C	p.Y302H	Substitution - Missense	Soft_tissue
COSM4532770	c.1917G>A	p.R639R	Substitution - coding silent	Skin
COSM3615208	c.1275C>T	p.L425L	Substitution - coding silent	Skin
COSM1173128	c.151T>C	p.Y51H	Substitution - Missense	Oesophagus
COSM136470	c.850G>A	p.E284K	Substitution - Missense	Skin
COSM3947397	c.1380C>G	p.S460S	Substitution - coding silent	Lung
COSM3013872	c.2453A>T	p.H818L	Substitution - Missense	Upper_aerodigestive_tract
COSM4599879	c.2437T>A	p.F813I	Substitution - Missense	Upper_aerodigestive_tract
COSM4988906	c.1907A>T	p.Y636F	Substitution - Missense	Soft_tissue
COSM4400253	c.1248C>T	p.F416F	Substitution - coding silent	Skin
COSM1067078	c.1034G>A	p.R345Q	Substitution - Missense	Endometrium
COSM1067093	c.2379T>A	p.S793R	Substitution - Missense	Endometrium
COSM365310	c.669A>T	p.T223T	Substitution - coding silent	Lung
COSM738277	c.1542G>T	p.V514V	Substitution - coding silent	Soft_tissue
COSM5434727	c.372C>T	p.F124F	Substitution - coding silent	Skin
COSM3854573	c.1586G>A	p.C529Y	Substitution - Missense	Stomach
COSM4460446	c.1166C>T	p.P389L	Substitution - Missense	Skin
COSM4976682	c.86A>G	p.K29R	Substitution - Missense	Oesophagus
COSM3373847	c.2599C>T	p.R867W	Substitution - Missense	Thyroid
COSM5026275	c.516_518delGAA	p.K174delK	Deletion - In frame	Breast
COSM1436881	c.929A>C	p.K310T	Substitution - Missense	Large_intestine
COSM738278	c.1505A>T	p.Q502L	Substitution - Missense	Soft_tissue
COSM1486703	c.2126C>G	p.T709S	Substitution - Missense	Liver
COSM5038138	c.2446A>C	p.K816Q	Substitution - Missense	Skin
COSM3941288	c.469G>T	p.E157*	Substitution - Nonsense	Oesophagus
COSM3013843	c.1939C>T	p.R647W	Substitution - Missense	Skin
COSM5639367	c.1303C>A	p.Q435K	Substitution - Missense	Oesophagus
COSM168243	c.58C>T	p.R20W	Substitution - Missense	Large_intestine
COSM5434727	c.372C>T	p.F124F	Substitution - coding silent	Skin
COSM3615212	c.1309C>T	p.Q437*	Substitution - Nonsense	Skin
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM4914435	c.1997G>A	p.C666Y	Substitution - Missense	Liver
COSM3013769	c.379G>A	p.E127K	Substitution - Missense	Skin
COSM1162655	c.888C>G	p.T296T	Substitution - coding silent	Pancreas
COSM1486703	c.2126C>G	p.T709S	Substitution - Missense	Liver
COSM5556671	c.1792C>T	p.H598Y	Substitution - Missense	Prostate
COSM3429362	c.999C>T	p.F333F	Substitution - coding silent	Large_intestine
COSM4407051	c.2276A>G	p.D759G	Substitution - Missense	Liver
COSM1436878	c.550C>T	p.R184*	Substitution - Nonsense	Large_intestine
COSM3410222	c.2483G>T	p.G828V	Substitution - Missense	Central_nervous_system
COSM125571	c.2273G>A	p.R758H	Substitution - Missense	Pancreas
COSM1067072	c.836G>A	p.R279Q	Substitution - Missense	Endometrium
COSM3827920	c.2544C>T	p.L848L	Substitution - coding silent	Breast
COSM1328854	c.478A>T	p.T160S	Substitution - Missense	Ovary
COSM3013881	c.2524C>T	p.R842C	Substitution - Missense	Oesophagus
COSM1067070	c.752C>G	p.S251*	Substitution - Nonsense	Endometrium
COSM5356593	c.933C>T	p.S311S	Substitution - coding silent	Large_intestine
COSM4751231	c.1673G>A	p.G558E	Substitution - Missense	Stomach
COSM317903	c.2515C>A	p.R839R	Substitution - coding silent	Lung
COSM3615223	c.2454C>T	p.H818H	Substitution - coding silent	Skin
COSM125571	c.2273G>A	p.R758H	Substitution - Missense	Endometrium
COSM3013871	c.2452C>G	p.H818D	Substitution - Missense	Upper_aerodigestive_tract
COSM5403283	c.1534T>A	p.L512I	Substitution - Missense	Skin
COSM1067093	c.2379T>A	p.S793R	Substitution - Missense	Oesophagus
COSM5652794	c.66C>T	p.P22P	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM4527306	c.1454G>A	p.G485E	Substitution - Missense	Skin
COSM5682877	c.2011C>A	p.R671R	Substitution - coding silent	Soft_tissue
COSM1262957	c.631T>G	p.F211V	Substitution - Missense	Oesophagus
COSM1067094	c.2496T>C	p.Y832Y	Substitution - coding silent	Prostate
COSM362330	c.1311G>T	p.Q437H	Substitution - Missense	Lung
COSM3744828	c.79G>A	p.A27T	Substitution - Missense	Liver
COSM4717521	c.557G>T	p.R186I	Substitution - Missense	Large_intestine
COSM125566	c.104T>A	p.F35Y	Substitution - Missense	Upper_aerodigestive_tract
COSM336830	c.2576C>A	p.P859H	Substitution - Missense	Lung
COSM351203	c.942C>A	p.N314K	Substitution - Missense	Lung
COSM4831960	c.1017C>T	p.I339I	Substitution - coding silent	Cervix
COSM1241617	c.2209A>G	p.R737G	Substitution - Missense	Oesophagus
COSM4526464	c.1398G>A	p.R466R	Substitution - coding silent	Liver
COSM364004	c.967C>A	p.R323R	Substitution - coding silent	Upper_aerodigestive_tract
COSM1436886	c.1402T>C	p.W468R	Substitution - Missense	Large_intestine
COSM5956407	c.1774C>A	p.Q592K	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM246767	c.338G>A	p.R113H	Substitution - Missense	Large_intestine
COSM5403281	c.139G>A	p.E47K	Substitution - Missense	Skin
COSM257805	c.1387T>G	p.L463V	Substitution - Missense	Large_intestine
COSM1067071	c.835C>T	p.R279*	Substitution - Nonsense	Endometrium
COSM3827918	c.713C>T	p.S238L	Substitution - Missense	Breast
COSM3393521	c.610+7G>T	p.?	Unknown	Pancreas
COSM3615207	c.1265G>A	p.R422K	Substitution - Missense	Skin
COSM738275	c.1834G>A	p.E612K	Substitution - Missense	Lung
COSM4791807	c.1451T>C	p.M484T	Substitution - Missense	Liver
COSM4985618	c.2137A>G	p.T713A	Substitution - Missense	Soft_tissue
COSM4560081	c.829G>A	p.E277K	Substitution - Missense	Skin
COSM1436878	c.550C>T	p.R184*	Substitution - Nonsense	Large_intestine
COSM5700861	c.1386C>A	p.L462L	Substitution - coding silent	Soft_tissue
COSM1262957	c.631T>G	p.F211V	Substitution - Missense	Large_intestine
COSM1067094	c.2496T>C	p.Y832Y	Substitution - coding silent	Prostate
COSM4970809	c.131G>T	p.G44V	Substitution - Missense	Central_nervous_system
COSM4717522	c.630C>T	p.N210N	Substitution - coding silent	Large_intestine
COSM5686752	c.710G>T	p.R237L	Substitution - Missense	Soft_tissue
COSM4851043	c.595G>A	p.D199N	Substitution - Missense	Cervix
COSM322807	c.1544G>C	p.G515A	Substitution - Missense	Lung
COSM337942	c.1465G>T	p.V489L	Substitution - Missense	Lung
COSM1311073	c.627G>C	p.Q209H	Substitution - Missense	Urinary_tract
COSM3770402	c.250C>T	p.Q84*	Substitution - Nonsense	Soft_tissue
COSM231055	c.1790C>G	p.T597S	Substitution - Missense	Thyroid
COSM2154557	c.710G>A	p.R237H	Substitution - Missense	Oesophagus
COSM3013834	c.1656C>T	p.Y552Y	Substitution - coding silent	Upper_aerodigestive_tract
COSM314414	c.1675C>A	p.R559R	Substitution - coding silent	Soft_tissue
COSM263091	c.1365G>T	p.E455D	Substitution - Missense	Soft_tissue
COSM3615203	c.893G>A	p.G298E	Substitution - Missense	Skin
COSM5029463	c.2306C>G	p.T769R	Substitution - Missense	Bone
COSM3854564	c.429T>A	p.S143R	Substitution - Missense	Stomach
COSM1486703	c.2126C>G	p.T709S	Substitution - Missense	Liver
COSM5030160	c.2347C>T	p.R783W	Substitution - Missense	Bone
COSM1067094	c.2496T>C	p.Y832Y	Substitution - coding silent	Urinary_tract
COSM284222	c.394G>T	p.E132*	Substitution - Nonsense	Stomach
COSM392250	c.424delG	p.A142fs*26	Deletion - Frameshift	Lung
COSM1067057	c.95C>A	p.S32Y	Substitution - Missense	Endometrium
COSM3013770	c.383C>G	p.S128C	Substitution - Missense	Breast
COSM4443022	c.358C>T	p.P120S	Substitution - Missense	Large_intestine
COSM1067083	c.1344T>C	p.N448N	Substitution - coding silent	Endometrium
COSM3013745	c.10G>T	p.E4*	Substitution - Nonsense	Stomach
COSM358016	c.174T>A	p.Y58*	Substitution - Nonsense	Lung
COSM1067094	c.2496T>C	p.Y832Y	Substitution - coding silent	Urinary_tract
COSM3615221	c.2301G>A	p.Q767Q	Substitution - coding silent	Skin
COSM5040814	c.1668G>C	p.E556D	Substitution - Missense	Liver
COSM3947401	c.2510G>T	p.C837F	Substitution - Missense	Lung
COSM125571	c.2273G>A	p.R758H	Substitution - Missense	Breast
COSM269943	c.1290C>A	p.P430P	Substitution - coding silent	Large_intestine
COSM1262957	c.631T>G	p.F211V	Substitution - Missense	Stomach
COSM1436883	c.1125A>T	p.K375N	Substitution - Missense	Large_intestine
COSM3393520	c.591G>A	p.P197P	Substitution - coding silent	Central_nervous_system
COSM3615200	c.698G>A	p.G233E	Substitution - Missense	Skin
COSM1262965	c.281A>C	p.E94A	Substitution - Missense	Stomach
COSM1067094	c.2496T>C	p.Y832Y	Substitution - coding silent	Bone
COSM3615198	c.630C>A	p.N210K	Substitution - Missense	Skin
COSM228063	c.1337G>A	p.S446N	Substitution - Missense	Urinary_tract
COSM3013872	c.2453A>T	p.H818L	Substitution - Missense	Upper_aerodigestive_tract
COSM1720121	c.1883G>A	p.R628K	Substitution - Missense	Skin
COSM5669369	c.2590G>T	p.E864*	Substitution - Nonsense	Soft_tissue
COSM72281	c.1148C>G	p.P383R	Substitution - Missense	Ovary
COSM3827919	c.1872C>T	p.L624L	Substitution - coding silent	Breast
COSM5403286	c.2546G>A	p.R849K	Substitution - Missense	Skin
COSM738289	c.194-1G>C	p.?	Unknown	Lung
COSM5697188	c.2280G>A	p.K760K	Substitution - coding silent	Soft_tissue
COSM1436884	c.1315C>T	p.Q439*	Substitution - Nonsense	Large_intestine
COSM5662890	c.1425C>A	p.A475A	Substitution - coding silent	Soft_tissue
COSM3013881	c.2524C>T	p.R842C	Substitution - Missense	Upper_aerodigestive_tract
COSM4981211	c.1527A>G	p.T509T	Substitution - coding silent	Oesophagus
COSM5822810	c.1177T>A	p.C393S	Substitution - Missense	Liver
COSM3947402	c.2513G>T	p.G838V	Substitution - Missense	Lung
COSM1067068	c.553G>T	p.E185*	Substitution - Nonsense	Endometrium
COSM4597864	c.2272C>A	p.R758S	Substitution - Missense	Upper_aerodigestive_tract
COSM5756645	c.118T>A	p.W40R	Substitution - Missense	Large_intestine
COSM317906	c.25G>C	p.E9Q	Substitution - Missense	Lung
COSM3615214	c.1386C>T	p.L462L	Substitution - coding silent	Skin
COSM284224	c.1644G>T	p.G548G	Substitution - coding silent	Large_intestine
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Thyroid
COSM1067094	c.2496T>C	p.Y832Y	Substitution - coding silent	Prostate
COSM1067081	c.1248C>A	p.F416L	Substitution - Missense	Endometrium
COSM5809515	c.521A>T	p.K174M	Substitution - Missense	Liver
COSM3013873	c.2457C>T	p.L819L	Substitution - coding silent	Skin
COSM1720120	c.1145-1G>A	p.?	Unknown	Skin
COSM738283	c.765G>T	p.Q255H	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3947391	c.854A>G	p.E285G	Substitution - Missense	Lung
COSM5403284	c.1708C>T	p.H570Y	Substitution - Missense	Skin
COSM3013881	c.2524C>T	p.R842C	Substitution - Missense	Breast
COSM1436886	c.1402T>C	p.W468R	Substitution - Missense	Stomach
COSM3975486	c.1675C>T	p.R559W	Substitution - Missense	Pancreas
COSM84890	c.1602T>G	p.S534R	Substitution - Missense	Pancreas
COSM314411	c.410C>T	p.A137V	Substitution - Missense	Lung
COSM5975572	c.2368A>C	p.N790H	Substitution - Missense	Upper_aerodigestive_tract
COSM125571	c.2273G>A	p.R758H	Substitution - Missense	Upper_aerodigestive_tract
COSM72282	c.2480C>G	p.T827R	Substitution - Missense	Ovary
COSM4513302	c.932C>T	p.S311F	Substitution - Missense	Skin
COSM5770731	c.2487G>C	p.E829D	Substitution - Missense	Breast
COSM145809	c.827A>T	p.Y276F	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5809515	c.521A>T	p.K174M	Substitution - Missense	Liver
COSM322809	c.1499C>A	p.T500K	Substitution - Missense	Lung
COSM4717525	c.1559G>T	p.R520I	Substitution - Missense	Large_intestine
COSM395303	c.2298C>A	p.H766Q	Substitution - Missense	Lung
COSM4974947	c.175A>T	p.N59Y	Substitution - Missense	Oesophagus
COSM351202	c.582C>A	p.V194V	Substitution - coding silent	Lung
COSM228063	c.1337G>A	p.S446N	Substitution - Missense	Skin
COSM3013870	c.2443A>T	p.N815Y	Substitution - Missense	Skin
COSM3393521	c.610+7G>T	p.?	Unknown	Pancreas
COSM125570	c.1634C>G	p.T545R	Substitution - Missense	Upper_aerodigestive_tract
COSM4891331	c.2368A>T	p.N790Y	Substitution - Missense	Upper_aerodigestive_tract
COSM4396343	c.112G>A	p.E38K	Substitution - Missense	Skin
COSM4527765	c.1489G>A	p.E497K	Substitution - Missense	Skin
COSM3615224	c.2483G>A	p.G828E	Substitution - Missense	Skin
COSM1486703	c.2126C>G	p.T709S	Substitution - Missense	Prostate
COSM738276	c.1759C>A	p.R587R	Substitution - coding silent	Lung
COSM738288	c.195T>C	p.G65G	Substitution - coding silent	Lung
COSM385949	c.7C>A	p.P3T	Substitution - Missense	Lung
COSM5367678	c.508+5_508+6insA	p.?	Unknown	Large_intestine
COSM4538466	c.2553G>T	p.Q851H	Substitution - Missense	Skin
COSM163710	c.1078G>A	p.E360K	Substitution - Missense	Breast
COSM5756645	c.118T>A	p.W40R	Substitution - Missense	Large_intestine
COSM3410221	c.2233G>T	p.E745*	Substitution - Nonsense	Central_nervous_system
COSM1067094	c.2496T>C	p.Y832Y	Substitution - coding silent	Prostate
COSM3854570	c.1251A>G	p.P417P	Substitution - coding silent	Stomach
COSM4597864	c.2272C>A	p.R758S	Substitution - Missense	Oesophagus
COSM1067059	c.249C>T	p.L83L	Substitution - coding silent	Endometrium
COSM332075	c.949_950AG>TT	p.R317>?	Complex	Lung
COSM738287	c.208C>T	p.R70*	Substitution - Nonsense	Lung
COSM166748	c.2295A>T	p.R765S	Substitution - Missense	Lung
COSM3854574	c.1758G>C	p.G586G	Substitution - coding silent	Stomach
COSM1262966	c.1014G>T	p.Q338H	Substitution - Missense	Stomach
COSM3748302	c.2431C>T	p.R811W	Substitution - Missense	Central_nervous_system
COSM2151207	c.1007A>T	p.H336L	Substitution - Missense	Central_nervous_system
COSM226556	c.2023T>C	p.W675R	Substitution - Missense	Skin
COSM125565	c.31C>A	p.P11T	Substitution - Missense	Upper_aerodigestive_tract
COSM4400253	c.1248C>T	p.F416F	Substitution - coding silent	Skin
COSM5049100	c.32C>A	p.P11Q	Substitution - Missense	Oesophagus
COSM5011390	c.976G>A	p.E326K	Substitution - Missense	Kidney
COSM5403280	c.76G>A	p.D26N	Substitution - Missense	Skin
COSM3919886	c.557G>A	p.R186K	Substitution - Missense	Skin
COSM1242712	c.338G>T	p.R113L	Substitution - Missense	Oesophagus
COSM314411	c.410C>T	p.A137V	Substitution - Missense	Soft_tissue
COSM3013856	c.2284C>G	p.H762D	Substitution - Missense	Breast
COSM4717523	c.1043G>A	p.R348K	Substitution - Missense	Large_intestine
COSM1067072	c.836G>A	p.R279Q	Substitution - Missense	Endometrium
COSM1567726	c.2190C>A	p.S730R	Substitution - Missense	Liver
COSM4609155	c.1650G>T	p.K550N	Substitution - Missense	Adrenal_gland
COSM5559383	c.1062G>T	p.L354L	Substitution - coding silent	Prostate
COSM5403281	c.139G>A	p.E47K	Substitution - Missense	Skin
COSM3661775	c.2565A>T	p.T855T	Substitution - coding silent	Liver
COSM4504298	c.661C>A	p.P221T	Substitution - Missense	Skin
COSM1436878	c.550C>T	p.R184*	Substitution - Nonsense	Bone
COSM3947389	c.6C>A	p.S2R	Substitution - Missense	Lung
COSM393712	c.2275G>A	p.D759N	Substitution - Missense	Lung
COSM4538806	c.2601G>A	p.R867R	Substitution - coding silent	Skin
COSM5002282	c.1981G>T	p.E661*	Substitution - Nonsense	Pancreas
COSM1436889	c.2011C>T	p.R671W	Substitution - Missense	Large_intestine
COSM5760375	c.2316G>T	p.G772G	Substitution - coding silent	Bone
COSM314410	c.2138C>G	p.T713R	Substitution - Missense	Lung
COSM1067095	c.2516G>A	p.R839Q	Substitution - Missense	Large_intestine
COSM4717527	c.1958C>G	p.T653S	Substitution - Missense	Large_intestine
COSM3013872	c.2453A>T	p.H818L	Substitution - Missense	Thyroid
COSM3429359	c.29G>A	p.S10N	Substitution - Missense	Large_intestine
COSM738291	c.168G>T	p.R56S	Substitution - Missense	Lung
COSM2155191	c.939C>A	p.A313A	Substitution - coding silent	Central_nervous_system
COSM5726137	c.156G>A	p.R52R	Substitution - coding silent	Skin
COSM263091	c.1365G>T	p.E455D	Substitution - Missense	Large_intestine
COSM1173129	c.2588G>A	p.R863K	Substitution - Missense	Oesophagus
COSM3615219	c.1643G>A	p.G548E	Substitution - Missense	Skin
COSM3947393	c.1108G>A	p.G370S	Substitution - Missense	Lung
COSM302985	c.2525G>A	p.R842H	Substitution - Missense	Large_intestine
COSM125572	c.2551C>A	p.Q851K	Substitution - Missense	Upper_aerodigestive_tract
COSM1067080	c.1242G>A	p.Q414Q	Substitution - coding silent	Endometrium
COSM5403285	c.2316G>A	p.G772G	Substitution - coding silent	Skin
COSM1262961	c.1474A>C	p.R492R	Substitution - coding silent	Oesophagus
COSM1436895	c.2664C>T	p.Y888Y	Substitution - coding silent	Stomach
COSM4850867	c.362A>G	p.K121R	Substitution - Missense	Cervix
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM3919885	c.277G>A	p.E93K	Substitution - Missense	Skin
COSM3393520	c.591G>A	p.P197P	Substitution - coding silent	Pancreas
COSM4526464	c.1398G>A	p.R466R	Substitution - coding silent	Skin
COSM4529215	c.1594G>A	p.G532S	Substitution - Missense	Skin
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM4974773	c.823C>T	p.P275S	Substitution - Missense	Oesophagus
COSM118342	c.1959T>C	p.T653T	Substitution - coding silent	Ovary
COSM1067064	c.394G>C	p.E132Q	Substitution - Missense	Endometrium
COSM5021467	c.2463A>T	p.R821S	Substitution - Missense	Bone
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM1720120	c.1145-1G>A	p.?	Unknown	Skin
COSM3013857	c.2285A>T	p.H762L	Substitution - Missense	Upper_aerodigestive_tract
COSM5924374	c.80C>T	p.A27V	Substitution - Missense	Skin
COSM738282	c.885C>A	p.I295I	Substitution - coding silent	Lung
COSM3013853	c.2188A>C	p.S730R	Substitution - Missense	Soft_tissue
COSM4159840	c.2191A>G	p.N731D	Substitution - Missense	Large_intestine
COSM738279	c.1475G>A	p.R492K	Substitution - Missense	Skin
COSM591873	c.2412T>C	p.Y804Y	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM5047707	c.1372G>C	p.E458Q	Substitution - Missense	Oesophagus
COSM3854578	c.2611G>A	p.D871N	Substitution - Missense	Stomach
COSM5679757	c.310C>G	p.P104A	Substitution - Missense	Soft_tissue
COSM364652	c.379G>T	p.E127*	Substitution - Nonsense	Lung
COSM5502944	c.820G>T	p.G274C	Substitution - Missense	Biliary_tract
COSM3854562	c.365C>A	p.A122E	Substitution - Missense	Stomach
COSM5764601	c.1078G>T	p.E360*	Substitution - Nonsense	Large_intestine
COSM1319204	c.2233G>A	p.E745K	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4597864	c.2272C>A	p.R758S	Substitution - Missense	Upper_aerodigestive_tract
COSM738273	c.2208C>A	p.L736L	Substitution - coding silent	Lung
COSM3615215	c.1469G>A	p.G490E	Substitution - Missense	Skin
COSM3615222	c.2398G>A	p.G800R	Substitution - Missense	Skin
COSM3410215	c.521A>G	p.K174R	Substitution - Missense	Central_nervous_system
COSM4717524	c.1246T>G	p.F416V	Substitution - Missense	Large_intestine
COSM4884311	c.1085G>A	p.G362D	Substitution - Missense	Upper_aerodigestive_tract
COSM4460337	c.1161C>T	p.I387I	Substitution - coding silent	Skin
COSM1262959	c.275A>G	p.D92G	Substitution - Missense	Oesophagus
COSM322804	c.122C>A	p.A41E	Substitution - Missense	Lung
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM5885593	c.2356A>C	p.R786R	Substitution - coding silent	Urinary_tract
COSM1543412	c.782G>A	p.W261*	Substitution - Nonsense	Skin
COSM3661775	c.2565A>T	p.T855T	Substitution - coding silent	Liver
COSM3429362	c.999C>T	p.F333F	Substitution - coding silent	Skin
COSM3615185	c.95C>T	p.S32F	Substitution - Missense	Skin
COSM3615203	c.893G>A	p.G298E	Substitution - Missense	Skin
COSM5671394	c.1546G>T	p.V516L	Substitution - Missense	Soft_tissue
COSM4507871	c.759C>T	p.I253I	Substitution - coding silent	Skin
COSM3615225	c.2492C>T	p.P831L	Substitution - Missense	Skin
COSM3373845	c.1071T>A	p.Y357*	Substitution - Nonsense	Thyroid
COSM317906	c.25G>C	p.E9Q	Substitution - Missense	Soft_tissue
COSM4717520	c.194-2A>G	p.?	Unknown	Large_intestine
COSM331455	c.882+1G>T	p.?	Unknown	Lung
COSM1067092	c.2319G>T	p.E773D	Substitution - Missense	Endometrium
COSM3393521	c.610+7G>T	p.?	Unknown	Pancreas
COSM3615217	c.1482G>T	p.M494I	Substitution - Missense	Skin
COSM291419	c.2179C>T	p.R727W	Substitution - Missense	Large_intestine
COSM4478974	c.2282C>T	p.S761L	Substitution - Missense	Skin
COSM4794621	c.696G>A	p.K232K	Substitution - coding silent	Liver
COSM4894310	c.2576C>T	p.P859L	Substitution - Missense	Skin
COSM3975487	c.2490G>A	p.K830K	Substitution - coding silent	Central_nervous_system
COSM3674427	c.2263C>T	p.R755W	Substitution - Missense	Prostate
COSM4451302	c.114A>T	p.E38D	Substitution - Missense	Skin
COSM4538192	c.2512G>A	p.G838R	Substitution - Missense	Skin
COSM307104	c.561G>A	p.K187K	Substitution - coding silent	Central_nervous_system
COSM3013820	c.1397G>C	p.R466T	Substitution - Missense	Skin
COSM269942	c.306A>G	p.K102K	Substitution - coding silent	Large_intestine
COSM226978	c.1802C>G	p.T601R	Substitution - Missense	Skin
COSM3919890	c.1761G>A	p.R587R	Substitution - coding silent	Skin
COSM360007	c.1749G>T	p.R583S	Substitution - Missense	Lung
COSM1067086	c.1631G>T	p.R544M	Substitution - Missense	Endometrium
COSM267253	c.1759C>T	p.R587W	Substitution - Missense	Large_intestine
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM4532567	c.1897G>A	p.E633K	Substitution - Missense	Skin
COSM121632	c.321C>T	p.A107A	Substitution - coding silent	Upper_aerodigestive_tract
COSM4978800	c.937G>T	p.A313S	Substitution - Missense	Oesophagus
COSM302985	c.2525G>A	p.R842H	Substitution - Missense	Central_nervous_system
COSM5440950	c.1620T>A	p.I540I	Substitution - coding silent	Oesophagus
COSM387530	c.730C>T	p.P244S	Substitution - Missense	Lung
COSM5437502	c.248T>C	p.L83P	Substitution - Missense	Oesophagus
COSM3854572	c.1577A>G	p.Y526C	Substitution - Missense	Stomach
COSM4451503	c.1251A>T	p.P417P	Substitution - coding silent	Skin
COSM3013760	c.219delC	p.F73fs*36	Deletion - Frameshift	Oesophagus
COSM4429281	c.643A>T	p.S215C	Substitution - Missense	Oesophagus
COSM3854565	c.552A>T	p.R184R	Substitution - coding silent	Stomach
COSM5496331	c.727C>T	p.P243S	Substitution - Missense	Biliary_tract
COSM296120	c.1855C>T	p.R619W	Substitution - Missense	Large_intestine
COSM125571	c.2273G>A	p.R758H	Substitution - Missense	Prostate
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM290132	c.1843C>T	p.R615W	Substitution - Missense	Large_intestine
COSM3919889	c.844G>A	p.E282K	Substitution - Missense	Skin
COSM1311075	c.1488A>C	p.E496D	Substitution - Missense	Urinary_tract
COSM5631188	c.2556G>T	p.R852S	Substitution - Missense	Oesophagus
COSM4519460	c.1010G>A	p.R337K	Substitution - Missense	Skin
COSM4461141	c.1193C>T	p.S398L	Substitution - Missense	Skin
COSM4141762	c.1800G>C	p.R600S	Substitution - Missense	Ovary
COSM3854575	c.2299C>T	p.Q767*	Substitution - Nonsense	Stomach
COSM1067073	c.889A>T	p.K297*	Substitution - Nonsense	Endometrium
COSM5434727	c.372C>T	p.F124F	Substitution - coding silent	Oesophagus
COSM591880	c.1404G>A	p.W468*	Substitution - Nonsense	Large_intestine
COSM1436887	c.1468G>T	p.G490*	Substitution - Nonsense	Oesophagus
COSM3615195	c.516G>A	p.R172R	Substitution - coding silent	Skin
COSM1262957	c.631T>G	p.F211V	Substitution - Missense	Large_intestine
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM5672893	c.2646C>T	p.H882H	Substitution - coding silent	Soft_tissue
COSM246767	c.338G>A	p.R113H	Substitution - Missense	Prostate
COSM4526464	c.1398G>A	p.R466R	Substitution - coding silent	Liver
COSM4597867	c.243C>G	p.I81M	Substitution - Missense	Upper_aerodigestive_tract
COSM5935045	c.272C>T	p.S91F	Substitution - Missense	Skin
COSM4791807	c.1451T>C	p.M484T	Substitution - Missense	Liver
COSM2152702	c.1760G>A	p.R587Q	Substitution - Missense	Central_nervous_system
COSM226129	c.2358A>C	p.R786S	Substitution - Missense	Endometrium
COSM317904	c.803C>A	p.P268Q	Substitution - Missense	Lung
COSM3615229	c.2601G>T	p.R867R	Substitution - coding silent	Skin
COSM5639699	c.410C>A	p.A137E	Substitution - Missense	Oesophagus
COSM226979	c.2440A>C	p.S814R	Substitution - Missense	Large_intestine
COSM4513302	c.932C>T	p.S311F	Substitution - Missense	Skin
COSM738268	c.2373C>A	p.L791L	Substitution - coding silent	Lung
COSM396132	c.2148G>A	p.G716G	Substitution - coding silent	Lung
COSM126879	c.2259T>A	p.C753*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM389521	c.2184C>A	p.G728G	Substitution - coding silent	Lung
COSM1486703	c.2126C>G	p.T709S	Substitution - Missense	Large_intestine
COSM3410218	c.1491G>C	p.E497D	Substitution - Missense	Central_nervous_system
COSM1720121	c.1883G>A	p.R628K	Substitution - Missense	Skin
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM354479	c.507G>T	p.L169L	Substitution - coding silent	Lung
COSM5466426	c.729C>T	p.P243P	Substitution - coding silent	Large_intestine
COSM5868375	c.916G>A	p.D306N	Substitution - Missense	Skin
COSM231055	c.1790C>G	p.T597S	Substitution - Missense	Large_intestine
COSM360006	c.936G>T	p.W312C	Substitution - Missense	Lung
COSM5662891	c.1540delG	p.V514fs*3	Deletion - Frameshift	Soft_tissue
COSM5537571	c.763C>T	p.Q255*	Substitution - Nonsense	Soft_tissue
COSM3615228	c.2590G>A	p.E864K	Substitution - Missense	Skin
COSM1067072	c.836G>A	p.R279Q	Substitution - Missense	Large_intestine
COSM166748	c.2295A>T	p.R765S	Substitution - Missense	Upper_aerodigestive_tract
COSM314412	c.2114C>T	p.S705L	Substitution - Missense	Lung
COSM3975485	c.877T>A	p.W293R	Substitution - Missense	Central_nervous_system
COSM5950871	c.2547A>T	p.R849S	Substitution - Missense	Prostate
COSM3919893	c.2303G>A	p.R768K	Substitution - Missense	Skin
COSM4408067	c.14A>C	p.K5T	Substitution - Missense	Oesophagus
COSM226557	c.2527A>G	p.N843D	Substitution - Missense	Skin
COSM1262963	c.2531A>C	p.K844T	Substitution - Missense	Oesophagus
COSM2151207	c.1007A>T	p.H336L	Substitution - Missense	Central_nervous_system
COSM3013870	c.2443A>T	p.N815Y	Substitution - Missense	Upper_aerodigestive_tract
COSM3615210	c.1289C>T	p.P430L	Substitution - Missense	Skin
COSM257803	c.900C>A	p.N300K	Substitution - Missense	Large_intestine
COSM5699639	c.1073G>T	p.G358V	Substitution - Missense	Soft_tissue
COSM3615187	c.168G>A	p.R56R	Substitution - coding silent	Skin
COSM1067065	c.415T>G	p.L139V	Substitution - Missense	Endometrium
COSM5434727	c.372C>T	p.F124F	Substitution - coding silent	Skin
COSM3615211	c.1300G>T	p.D434Y	Substitution - Missense	Skin
COSM5417544	c.732A>T	p.P244P	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM738293	c.79G>T	p.A27S	Substitution - Missense	Lung
COSM4486923	c.311C>T	p.P104L	Substitution - Missense	Skin
COSM1436882	c.1075G>A	p.D359N	Substitution - Missense	Large_intestine
COSM378428	c.2408C>A	p.P803H	Substitution - Missense	Lung
COSM5367678	c.508+5_508+6insA	p.?	Unknown	Large_intestine
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM738279	c.1475G>A	p.R492K	Substitution - Missense	Lung
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM738281	c.1034G>T	p.R345L	Substitution - Missense	Lung
COSM125567	c.593A>T	p.Q198L	Substitution - Missense	Upper_aerodigestive_tract
COSM284223	c.537G>T	p.K179N	Substitution - Missense	Large_intestine
COSM4597864	c.2272C>A	p.R758S	Substitution - Missense	Oesophagus
COSM1067071	c.835C>T	p.R279*	Substitution - Nonsense	Oesophagus
COSM5427613	c.2284C>T	p.H762Y	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM125565	c.31C>A	p.P11T	Substitution - Missense	Large_intestine
COSM3410216	c.679G>T	p.D227Y	Substitution - Missense	Central_nervous_system
COSM738286	c.368C>A	p.S123*	Substitution - Nonsense	Lung
COSM5480484	c.25G>A	p.E9K	Substitution - Missense	Large_intestine
COSM368180	c.1594G>C	p.G532R	Substitution - Missense	Lung
COSM3429363	c.2272C>T	p.R758C	Substitution - Missense	Pancreas
COSM3615184	c.10G>A	p.E4K	Substitution - Missense	Skin
COSM299439	c.69+5G>T	p.?	Unknown	Large_intestine
COSM738278	c.1505A>T	p.Q502L	Substitution - Missense	Lung
COSM3615204	c.894G>A	p.G298G	Substitution - coding silent	Skin
COSM5356703	c.1644G>A	p.G548G	Substitution - coding silent	Large_intestine
COSM738280	c.1326A>T	p.P442P	Substitution - coding silent	Lung
COSM5660105	c.2639G>A	p.R880K	Substitution - Missense	Soft_tissue
COSM3854578	c.2611G>A	p.D871N	Substitution - Missense	Skin
COSM4597864	c.2272C>A	p.R758S	Substitution - Missense	Large_intestine
COSM1067089	c.1781T>A	p.V594D	Substitution - Missense	Endometrium
COSM3393521	c.610+7G>T	p.?	Unknown	Pancreas
COSM4791122	c.2652G>C	p.G884G	Substitution - coding silent	Liver
COSM166748	c.2295A>T	p.R765S	Substitution - Missense	Bone
COSM4794621	c.696G>A	p.K232K	Substitution - coding silent	Liver
COSM3827921	c.2677G>C	p.D893H	Substitution - Missense	Breast
COSM1436891	c.2095C>T	p.R699W	Substitution - Missense	Large_intestine
COSM328165	c.504A>T	p.K168N	Substitution - Missense	Pancreas
COSM183450	c.1424C>A	p.A475D	Substitution - Missense	Large_intestine
COSM373184	c.842C>A	p.T281K	Substitution - Missense	Lung
COSM738272	c.2240C>A	p.P747H	Substitution - Missense	Lung
COSM226129	c.2358A>C	p.R786S	Substitution - Missense	Endometrium
COSM1436896	c.2665G>A	p.V889I	Substitution - Missense	Large_intestine
COSM4791122	c.2652G>C	p.G884G	Substitution - coding silent	Liver
COSM1067072	c.836G>A	p.R279Q	Substitution - Missense	Skin
COSM166748	c.2295A>T	p.R765S	Substitution - Missense	Breast
COSM116604	c.2058C>G	p.H686Q	Substitution - Missense	Ovary
COSM3854563	c.409G>A	p.A137T	Substitution - Missense	Stomach
COSM5975572	c.2368A>C	p.N790H	Substitution - Missense	Upper_aerodigestive_tract
COSM738283	c.765G>T	p.Q255H	Substitution - Missense	Lung
COSM1262964	c.198C>T	p.L66L	Substitution - coding silent	Stomach
COSM4604839	c.2417G>T	p.C806F	Substitution - Missense	Upper_aerodigestive_tract
COSM1067090	c.1890C>T	p.H630H	Substitution - coding silent	Endometrium
COSM1311076	c.1886G>C	p.R629T	Substitution - Missense	Bone
COSM3615190	c.331G>A	p.E111K	Substitution - Missense	Skin
COSM3615206	c.957G>A	p.V319V	Substitution - coding silent	Skin
COSM1221904	c.153T>A	p.Y51*	Substitution - Nonsense	Large_intestine
COSM3919892	c.2054C>G	p.T685R	Substitution - Missense	Skin
COSM3615216	c.1482G>A	p.M494I	Substitution - Missense	Skin
COSM3854577	c.2378G>A	p.S793N	Substitution - Missense	Stomach
COSM231055	c.1790C>G	p.T597S	Substitution - Missense	Prostate
COSM226557	c.2527A>G	p.N843D	Substitution - Missense	Skin
COSM50665	c.932C>A	p.S311Y	Substitution - Missense	Large_intestine
COSM3615194	c.509-1G>A	p.?	Unknown	Skin
COSM5048530	c.860C>G	p.A287G	Substitution - Missense	Oesophagus
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM226557	c.2527A>G	p.N843D	Substitution - Missense	Thyroid
COSM322805	c.1678G>T	p.G560C	Substitution - Missense	Lung
COSM3615189	c.310C>T	p.P104S	Substitution - Missense	Skin
COSM1436880	c.726G>T	p.L242L	Substitution - coding silent	Large_intestine
COSM1067093	c.2379T>A	p.S793R	Substitution - Missense	Endometrium
COSM76049	c.101A>G	p.Y34C	Substitution - Missense	Ovary
COSM145809	c.827A>T	p.Y276F	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1486703	c.2126C>G	p.T709S	Substitution - Missense	Upper_aerodigestive_tract
COSM1067094	c.2496T>C	p.Y832Y	Substitution - coding silent	Large_intestine
COSM1722544	c.2568G>A	p.G856G	Substitution - coding silent	Skin
COSM3615202	c.802C>T	p.P268S	Substitution - Missense	Skin
COSM3919892	c.2054C>G	p.T685R	Substitution - Missense	Large_intestine
COSM3919887	c.717C>T	p.A239A	Substitution - coding silent	Skin
COSM1262967	c.367T>C	p.S123P	Substitution - Missense	Oesophagus
COSM3615186	c.133G>A	p.D45N	Substitution - Missense	Skin
COSM1067066	c.506T>C	p.L169P	Substitution - Missense	Endometrium
COSM1067094	c.2496T>C	p.Y832Y	Substitution - coding silent	Prostate
COSM1567725	c.2436C>G	p.G812G	Substitution - coding silent	Large_intestine
COSM3615196	c.523G>A	p.E175K	Substitution - Missense	Skin
COSM137420	c.1453G>A	p.G485R	Substitution - Missense	Skin
COSM3615195	c.516G>A	p.R172R	Substitution - coding silent	Skin
COSM290132	c.1843C>T	p.R615W	Substitution - Missense	Endometrium
COSM1311074	c.1377G>A	p.R459R	Substitution - coding silent	Urinary_tract
COSM226129	c.2358A>C	p.R786S	Substitution - Missense	Skin
COSM4884549	c.652G>T	p.A218S	Substitution - Missense	Upper_aerodigestive_tract
COSM5765927	c.1696C>G	p.H566D	Substitution - Missense	Large_intestine
COSM1067060	c.272C>A	p.S91Y	Substitution - Missense	Endometrium
COSM4829436	c.14A>T	p.K5M	Substitution - Missense	Cervix
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM3615218	c.1516C>T	p.P506S	Substitution - Missense	Skin
COSM1067089	c.1781T>A	p.V594D	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM317902	c.697G>T	p.G233W	Substitution - Missense	Lung
COSM4604696	c.2081G>T	p.C694F	Substitution - Missense	Upper_aerodigestive_tract
COSM1221903	c.664C>T	p.P222S	Substitution - Missense	Large_intestine
COSM5419569	c.2455C>G	p.L819V	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM317902	c.697G>T	p.G233W	Substitution - Missense	Skin
COSM3947398	c.1803A>T	p.T601T	Substitution - coding silent	Lung
COSM4396343	c.112G>A	p.E38K	Substitution - Missense	Skin
COSM1067095	c.2516G>A	p.R839Q	Substitution - Missense	Skin
COSM1067082	c.1284G>T	p.E428D	Substitution - Missense	Endometrium
COSM1262958	c.724C>A	p.L242M	Substitution - Missense	Oesophagus
COSM3615191	c.353G>A	p.G118E	Substitution - Missense	Skin
COSM284225	c.2338G>T	p.E780*	Substitution - Nonsense	Large_intestine
COSM3013853	c.2188A>C	p.S730R	Substitution - Missense	Large_intestine
COSM4521034	c.1090G>A	p.E364K	Substitution - Missense	Skin
COSM4521980	c.1139G>A	p.G380E	Substitution - Missense	Skin
COSM1311076	c.1886G>C	p.R629T	Substitution - Missense	Skin
COSM3615189	c.310C>T	p.P104S	Substitution - Missense	Skin
COSM5724750	c.268G>A	p.D90N	Substitution - Missense	Skin
COSM1132172	c.1162C>T	p.H388Y	Substitution - Missense	Prostate
COSM4550299	c.497G>A	p.R166K	Substitution - Missense	Skin
COSM5931747	c.1580G>A	p.G527E	Substitution - Missense	Skin
COSM1221907	c.2506G>A	p.E836K	Substitution - Missense	Large_intestine
COSM1067077	c.1030T>C	p.C344R	Substitution - Missense	Endometrium
COSM3366037	c.1701C>T	p.L567L	Substitution - coding silent	Kidney
COSM1722544	c.2568G>A	p.G856G	Substitution - coding silent	Skin
COSM5048636	c.63G>T	p.K21N	Substitution - Missense	Oesophagus
COSM5696232	c.1198C>A	p.Q400K	Substitution - Missense	Soft_tissue
COSM4460446	c.1166C>T	p.P389L	Substitution - Missense	Liver
COSM5975571	c.783G>A	p.W261*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM5629598	c.2127T>A	p.T709T	Substitution - coding silent	Oesophagus
COSM317903	c.2515C>A	p.R839R	Substitution - coding silent	Soft_tissue
COSM482699	c.569C>A	p.A190E	Substitution - Missense	Kidney
COSM2152702	c.1760G>A	p.R587Q	Substitution - Missense	Central_nervous_system
COSM1311074	c.1377G>A	p.R459R	Substitution - coding silent	Skin
COSM1067093	c.2379T>A	p.S793R	Substitution - Missense	Endometrium
COSM3854560	c.48G>A	p.E16E	Substitution - coding silent	Stomach
COSM3919885	c.277G>A	p.E93K	Substitution - Missense	Skin
COSM1567726	c.2190C>A	p.S730R	Substitution - Missense	Thyroid
COSM1486703	c.2126C>G	p.T709S	Substitution - Missense	Liver
COSM5888882	c.1193C>G	p.S398*	Substitution - Nonsense	Skin
COSM3718650	c.2274C>A	p.R758R	Substitution - coding silent	Upper_aerodigestive_tract
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM3744829	c.1649A>T	p.K550M	Substitution - Missense	Liver
COSM4006008	c.2188A>G	p.S730G	Substitution - Missense	Urinary_tract
COSM166748	c.2295A>T	p.R765S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5931748	c.740G>A	p.R247K	Substitution - Missense	Skin
COSM1221907	c.2506G>A	p.E836K	Substitution - Missense	Skin
COSM4599986	c.1213C>A	p.Q405K	Substitution - Missense	Upper_aerodigestive_tract
COSM3947390	c.831G>T	p.E277D	Substitution - Missense	Lung
COSM5688893	c.1481T>C	p.M494T	Substitution - Missense	Soft_tissue
COSM3947396	c.1338C>A	p.S446R	Substitution - Missense	Lung
COSM4585818	c.2071delC	p.Y692fs*>203	Deletion - Frameshift	Bone
COSM4717529	c.2557_2558delAC	p.T855fs*15	Deletion - Frameshift	Large_intestine
COSM1543420	c.129G>T	p.M43I	Substitution - Missense	Central_nervous_system
COSM3410219	c.1553T>A	p.I518N	Substitution - Missense	Central_nervous_system
COSM3615205	c.925G>A	p.D309N	Substitution - Missense	Skin
COSM4006007	c.1718T>C	p.I573T	Substitution - Missense	Urinary_tract
COSM1311076	c.1886G>C	p.R629T	Substitution - Missense	Thyroid
COSM271048	c.1383A>T	p.K461N	Substitution - Missense	Large_intestine
COSM314413	c.2290C>T	p.L764F	Substitution - Missense	Lung
COSM4466377	c.1430C>T	p.S477F	Substitution - Missense	Skin
COSM1067095	c.2516G>A	p.R839Q	Substitution - Missense	Endometrium
COSM4905215	c.346C>T	p.Q116*	Substitution - Nonsense	Skin
COSM314410	c.2138C>G	p.T713R	Substitution - Missense	Large_intestine
COSM3615184	c.10G>A	p.E4K	Substitution - Missense	Skin
COSM322808	c.1377G>T	p.R459S	Substitution - Missense	Lung
COSM5569364	c.52A>G	p.T18A	Substitution - Missense	Prostate
COSM4838891	c.1022A>T	p.Y341F	Substitution - Missense	Cervix
COSM1067063	c.366G>A	p.A122A	Substitution - coding silent	Endometrium
COSM5724750	c.268G>A	p.D90N	Substitution - Missense	Skin
COSM341412	c.2651G>T	p.G884V	Substitution - Missense	Lung
COSM3975486	c.1675C>T	p.R559W	Substitution - Missense	Central_nervous_system
COSM3615227	c.2569G>A	p.E857K	Substitution - Missense	Skin
COSM50664	c.1567A>G	p.K523E	Substitution - Missense	Large_intestine
COSM4159840	c.2191A>G	p.N731D	Substitution - Missense	Thyroid
COSM4717526	c.1667A>G	p.E556G	Substitution - Missense	Large_intestine
COSM3393519	c.509-5C>A	p.?	Unknown	Pancreas
COSM5351187	c.2528A>G	p.N843S	Substitution - Missense	Lung
COSM3615219	c.1643G>A	p.G548E	Substitution - Missense	Skin
COSM121632	c.321C>T	p.A107A	Substitution - coding silent	Prostate
COSM405181	c.1548_1557del10	p.G517fs*>375	Deletion - Frameshift	Lung
COSM4717527	c.1958C>G	p.T653S	Substitution - Missense	Large_intestine
COSM5559386	c.1061T>G	p.L354R	Substitution - Missense	Prostate
COSM226978	c.1802C>G	p.T601R	Substitution - Missense	Lung
COSM3013871	c.2452C>G	p.H818D	Substitution - Missense	Large_intestine
COSM3615213	c.1368C>T	p.I456I	Substitution - coding silent	Skin
COSM4768124	c.2380C>T	p.H794Y	Substitution - Missense	Biliary_tract
COSM2154557	c.710G>A	p.R237H	Substitution - Missense	Central_nervous_system
COSM2156567	c.2348G>A	p.R783Q	Substitution - Missense	Central_nervous_system
COSM125571	c.2273G>A	p.R758H	Substitution - Missense	Upper_aerodigestive_tract
COSM346809	c.2469G>T	p.Q823H	Substitution - Missense	Lung
COSM1067074	c.907G>T	p.E303*	Substitution - Nonsense	Endometrium
COSM5038076	c.2444A>G	p.N815S	Substitution - Missense	Skin
COSM5048378	c.1661G>A	p.C554Y	Substitution - Missense	Oesophagus
COSM5242631	c.1110C>A	p.G370G	Substitution - coding silent	Oesophagus
COSM3947395	c.1145-4T>C	p.?	Unknown	Lung
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM5427613	c.2284C>T	p.H762Y	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4427483	c.653C>A	p.A218D	Substitution - Missense	Oesophagus
COSM738285	c.505C>A	p.L169M	Substitution - Missense	Lung
COSM4536586	c.2317G>A	p.E773K	Substitution - Missense	Skin
COSM5592680	c.636C>T	p.F212F	Substitution - coding silent	Skin
COSM3393521	c.610+7G>T	p.?	Unknown	Pancreas
COSM4939284	c.1332A>G	p.P444P	Substitution - coding silent	Liver
COSM3854561	c.279A>C	p.E93D	Substitution - Missense	Stomach
COSM4526464	c.1398G>A	p.R466R	Substitution - coding silent	Skin
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM1161539	c.199A>G	p.R67G	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1436892	c.2264G>A	p.R755Q	Substitution - Missense	Large_intestine
COSM348078	c.799C>G	p.L267V	Substitution - Missense	Lung
COSM5662286	c.1503delC	p.Q502fs*3	Deletion - Frameshift	Soft_tissue
COSM3854566	c.563G>C	p.G188A	Substitution - Missense	Stomach
COSM222053	c.1119G>A	p.W373*	Substitution - Nonsense	Skin
COSM296120	c.1855C>T	p.R619W	Substitution - Missense	Ovary
COSM3947392	c.1032C>A	p.C344*	Substitution - Nonsense	Lung
COSM267253	c.1759C>T	p.R587W	Substitution - Missense	Central_nervous_system
COSM3013869	c.2442C>A	p.S814R	Substitution - Missense	Large_intestine
COSM3615185	c.95C>T	p.S32F	Substitution - Missense	Skin
COSM3615189	c.310C>T	p.P104S	Substitution - Missense	Skin
COSM3919888	c.761C>T	p.P254L	Substitution - Missense	Skin
COSM5435376	c.36A>C	p.E12D	Substitution - Missense	Oesophagus
COSM3854561	c.279A>C	p.E93D	Substitution - Missense	Stomach
COSM5403281	c.139G>A	p.E47K	Substitution - Missense	Skin
COSM1543413	c.763C>A	p.Q255K	Substitution - Missense	Lung
COSM3373846	c.1565C>T	p.A522V	Substitution - Missense	Thyroid
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM375448	c.1093C>A	p.L365M	Substitution - Missense	Lung
COSM166748	c.2295A>T	p.R765S	Substitution - Missense	Upper_aerodigestive_tract
COSM400267	c.2315G>T	p.G772V	Substitution - Missense	Lung
COSM3854569	c.1202A>C	p.K401T	Substitution - Missense	Stomach
COSM1067093	c.2379T>A	p.S793R	Substitution - Missense	Large_intestine
COSM1067069	c.721A>G	p.S241G	Substitution - Missense	Endometrium
COSM1067084	c.1364A>G	p.E455G	Substitution - Missense	Endometrium
COSM4823015	c.1299G>T	p.G433G	Substitution - coding silent	Cervix
COSM591881	c.1389G>A	p.L463L	Substitution - coding silent	Endometrium
COSM360006	c.936G>T	p.W312C	Substitution - Missense	Lung
COSM257804	c.1011G>A	p.R337R	Substitution - coding silent	Large_intestine
COSM1262960	c.1766T>A	p.F589Y	Substitution - Missense	Oesophagus
COSM3718650	c.2274C>A	p.R758R	Substitution - coding silent	Upper_aerodigestive_tract
COSM4159839	c.2042C>G	p.T681S	Substitution - Missense	Upper_aerodigestive_tract
COSM3429363	c.2272C>T	p.R758C	Substitution - Missense	Large_intestine
COSM738269	c.2244T>C	p.Y748Y	Substitution - coding silent	Lung
COSM3393520	c.591G>A	p.P197P	Substitution - coding silent	Stomach
COSM5654730	c.1180T>G	p.C394G	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4525155	c.1312G>A	p.E438K	Substitution - Missense	Skin
COSM4839880	c.1265G>T	p.R422I	Substitution - Missense	Cervix
COSM284222	c.394G>T	p.E132*	Substitution - Nonsense	Large_intestine
COSM1436890	c.2077G>C	p.V693L	Substitution - Missense	Large_intestine
COSM3615192	c.451C>T	p.P151S	Substitution - Missense	Skin
COSM738292	c.98T>A	p.I33K	Substitution - Missense	Lung
COSM3615190	c.331G>A	p.E111K	Substitution - Missense	Skin
COSM3429361	c.970G>T	p.D324Y	Substitution - Missense	Large_intestine
COSM5403282	c.611-1G>A	p.?	Unknown	Skin
COSM5975572	c.2368A>C	p.N790H	Substitution - Missense	Upper_aerodigestive_tract
COSM738267	c.2573A>T	p.K858M	Substitution - Missense	Lung
COSM4988906	c.1907A>T	p.Y636F	Substitution - Missense	Soft_tissue
COSM1733993	c.760C>A	p.P254T	Substitution - Missense	Pancreas
COSM3410217	c.897A>G	p.R299R	Substitution - coding silent	Central_nervous_system
COSM1436896	c.2665G>A	p.V889I	Substitution - Missense	Pancreas
COSM2156567	c.2348G>A	p.R783Q	Substitution - Missense	Central_nervous_system
COSM384815	c.1457G>T	p.S486I	Substitution - Missense	Lung
COSM226129	c.2358A>C	p.R786S	Substitution - Missense	Large_intestine
COSM1067062	c.366G>T	p.A122A	Substitution - coding silent	Endometrium

> Text Mining based Variations

[ TOP ]

PMID	Variation	Cancer	Evidence
23222848	Mutation	Leukemogenesis	Rare allelic forms of PRDM9 associated with childhood leukemogenesis.

Summary
Symbol	PRDM9
Name	PR/SET domain 9
Aliases	PFM6; ZNF899; PR-domain containing protein 9; MSBP3; minisatellite binding protein 3, 115kDa; minisatellite ......
Location	5p14.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM) [ TOP ]
There is no PTM data

Summary
Symbol	PRDM9
Name	PR/SET domain 9
Aliases	PFM6; ZNF899; PR-domain containing protein 9; MSBP3; minisatellite binding protein 3, 115kDa; minisatellite ......
Location	5p14.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> Cancer Cell Line Encyclopedia (CCLE)

[ TOP ]

Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	3.4
Autonomic ganglia	CHP212	3.6
Autonomic ganglia	IMR32	3.7
Autonomic ganglia	KELLY	3.5
Autonomic ganglia	KPNRTBM1	3.5
Autonomic ganglia	KPNSI9S	3.4
Autonomic ganglia	KPNYN	3.5
Autonomic ganglia	MHHNB11	3.8
Autonomic ganglia	NB1	3.6
Autonomic ganglia	NH6	3.5
Autonomic ganglia	SHSY5Y	3.6
Autonomic ganglia	SIMA	3.4
Autonomic ganglia	SKNAS	3.6
Autonomic ganglia	SKNBE2	3.3
Autonomic ganglia	SKNDZ	3.4
Autonomic ganglia	SKNFI	3.5
Autonomic ganglia	SKNSH	3.5
Biliary tract	HUCCT1	3.7
Biliary tract	HUH28	3.5
Biliary tract	SNU1079	3.6
Biliary tract	SNU1196	3.6
Biliary tract	SNU245	3.9
Biliary tract	SNU308	3.8
Biliary tract	SNU478	3.9
Bone	143B	3.6
Bone	A673	3.6
Bone	CADOES1	3.6
Bone	CAL78	3.6
Bone	G292CLONEA141B1	3.7
Bone	HOS	3.5
Bone	HS706T	3.7
Bone	HS737T	3.4
Bone	HS819T	3.6
Bone	HS821T	3.5
Bone	HS822T	3.7
Bone	HS863T	3.4
Bone	HS870T	3.8
Bone	HS888T	3.4
Bone	MG63	3.8
Bone	MHHES1	3.3
Bone	OUMS27	3.5
Bone	RDES	3.6
Bone	SJSA1	3.8
Bone	SKES1	3.5
Bone	SKNMC	3.7
Bone	SW1353	3.7
Bone	T173	3.7
Bone	TC71	3.9
Bone	U2OS	3.6
Breast	AU565	3.7
Breast	BT20	3.7
Breast	BT474	3.6
Breast	BT483	3.7
Breast	BT549	3.7
Breast	CAL120	3.4
Breast	CAL148	3.2
Breast	CAL51	3.5
Breast	CAL851	3.5
Breast	CAMA1	3.6
Breast	DU4475	4
Breast	EFM192A	3.6
Breast	EFM19	3.5
Breast	EVSAT	3.8
Breast	HCC1143	3.8
Breast	HCC1187	3.8
Breast	HCC1395	3.6
Breast	HCC1419	3.7
Breast	HCC1428	3.6
Breast	HCC1500	3.6
Breast	HCC1569	3.6
Breast	HCC1599	3.6
Breast	HCC1806	3.5
Breast	HCC1937	3.5
Breast	HCC1954	3.7
Breast	HCC202	3.5
Breast	HCC2157	3.7
Breast	HCC2218	3.7
Breast	HCC38	3.4
Breast	HCC70	3.7
Breast	HDQP1	3.6
Breast	HMC18	3.6
Breast	HS274T	3.5
Breast	HS281T	3.6
Breast	HS343T	3.5
Breast	HS578T	3.7
Breast	HS606T	3.5
Breast	HS739T	3.4
Breast	HS742T	3.6
Breast	JIMT1	3.5
Breast	KPL1	3.7
Breast	MCF7	3.5
Breast	MDAMB134VI	3.6
Breast	MDAMB157	3.5
Breast	MDAMB175VII	3.6
Breast	MDAMB231	3.8
Breast	MDAMB361	3.5
Breast	MDAMB415	3.6
Breast	MDAMB436	3.8
Breast	MDAMB453	3.5
Breast	MDAMB468	3.5
Breast	SKBR3	3.7
Breast	T47D	3.7
Breast	UACC812	3.8
Breast	UACC893	3.6
Breast	YMB1	3.9
Breast	ZR751	3.5
Breast	ZR7530	3.5
Central nervous system	1321N1	3.6
Central nervous system	42MGBA	3.6
Central nervous system	8MGBA	3.6
Central nervous system	A172	3.4
Central nervous system	AM38	3.8
Central nervous system	BECKER	3.5
Central nervous system	CAS1	3.8
Central nervous system	CCFSTTG1	3.7
Central nervous system	D283MED	3.5
Central nervous system	D341MED	3.7
Central nervous system	DAOY	3.8
Central nervous system	DBTRG05MG	3.4
Central nervous system	DKMG	3.8
Central nervous system	GAMG	3.4
Central nervous system	GB1	3.4
Central nervous system	GI1	3.8
Central nervous system	GMS10	3.5
Central nervous system	GOS3	3.9
Central nervous system	H4	3.8
Central nervous system	HS683	3.4
Central nervous system	KALS1	3.5
Central nervous system	KG1C	3.6
Central nervous system	KNS42	3.6
Central nervous system	KNS60	3.5
Central nervous system	KNS81	3.6
Central nervous system	KS1	3.5
Central nervous system	LN18	3.6
Central nervous system	LN229	3.5
Central nervous system	M059K	3.5
Central nervous system	MOGGCCM	3.7
Central nervous system	MOGGUVW	3.5
Central nervous system	NMCG1	3.5
Central nervous system	ONS76	3.7
Central nervous system	SF126	3.7
Central nervous system	SF295	3.8
Central nervous system	SNB19	3.5
Central nervous system	SNU1105	3.7
Central nervous system	SNU201	3.5
Central nervous system	SNU466	3.8
Central nervous system	SNU489	3.3
Central nervous system	SNU626	3.8
Central nervous system	SNU738	3.8
Central nervous system	SW1088	3.5
Central nervous system	SW1783	3.7
Central nervous system	T98G	3.5
Central nervous system	TM31	3.5
Central nervous system	U118MG	3.4
Central nervous system	U138MG	3.4
Central nervous system	U251MG	3.4
Central nervous system	U87MG	3.7
Central nervous system	YH13	3.5
Central nervous system	YKG1	3.4
Endometrium	AN3CA	3.7
Endometrium	COLO684	3.5
Endometrium	EFE184	3.7
Endometrium	EN	3.7
Endometrium	ESS1	3.5
Endometrium	HEC108	3.8
Endometrium	HEC151	3.9
Endometrium	HEC1A	3.6
Endometrium	HEC1B	3.6
Endometrium	HEC251	3.7
Endometrium	HEC265	3.6
Endometrium	HEC50B	3.6
Endometrium	HEC59	4.1
Endometrium	HEC6	3.5
Endometrium	ISHIKAWAHERAKLIO02ER	3.7
Endometrium	JHUEM1	3.7
Endometrium	JHUEM2	3.5
Endometrium	JHUEM3	3.5
Endometrium	KLE	3.6
Endometrium	MFE280	3.7
Endometrium	MFE296	3.6
Endometrium	MFE319	3.7
Endometrium	RL952	3.8
Endometrium	SNGM	3.5
Endometrium	SNU1077	3.6
Endometrium	SNU685	3.3
Endometrium	TEN	3.4
Haematopoietic and lymphoid	697	3.5
Haematopoietic and lymphoid	A3KAW	4
Haematopoietic and lymphoid	A4FUK	3.8
Haematopoietic and lymphoid	ALLSIL	3.6
Haematopoietic and lymphoid	AML193	3.7
Haematopoietic and lymphoid	AMO1	3.6
Haematopoietic and lymphoid	BCP1	3.9
Haematopoietic and lymphoid	BDCM	3.8
Haematopoietic and lymphoid	BL41	3.6
Haematopoietic and lymphoid	BL70	4.2
Haematopoietic and lymphoid	BV173	3.8
Haematopoietic and lymphoid	CA46	3.5
Haematopoietic and lymphoid	CI1	3.9
Haematopoietic and lymphoid	CMK115	3.6
Haematopoietic and lymphoid	CMK86	3.4
Haematopoietic and lymphoid	CMK	3.6
Haematopoietic and lymphoid	CMLT1	3.5
Haematopoietic and lymphoid	COLO775	3.5
Haematopoietic and lymphoid	DAUDI	3.9
Haematopoietic and lymphoid	DB	4.1
Haematopoietic and lymphoid	DEL	3.8
Haematopoietic and lymphoid	DND41	3.8
Haematopoietic and lymphoid	DOHH2	3.6
Haematopoietic and lymphoid	EB1	3.6
Haematopoietic and lymphoid	EB2	3.7
Haematopoietic and lymphoid	EHEB	3.8
Haematopoietic and lymphoid	EJM	3.8
Haematopoietic and lymphoid	EM2	3.5
Haematopoietic and lymphoid	EOL1	3.4
Haematopoietic and lymphoid	F36P	3.5
Haematopoietic and lymphoid	GA10	4
Haematopoietic and lymphoid	GDM1	3.6
Haematopoietic and lymphoid	GRANTA519	3.6
Haematopoietic and lymphoid	HDLM2	3.7
Haematopoietic and lymphoid	HDMYZ	3.4
Haematopoietic and lymphoid	HEL9217	3.6
Haematopoietic and lymphoid	HEL	3.6
Haematopoietic and lymphoid	HH	3.7
Haematopoietic and lymphoid	HL60	3.7
Haematopoietic and lymphoid	HPBALL	3.5
Haematopoietic and lymphoid	HS604T	3.7
Haematopoietic and lymphoid	HS611T	3.7
Haematopoietic and lymphoid	HS616T	3.7
Haematopoietic and lymphoid	HS751T	3.7
Haematopoietic and lymphoid	HT	3.7
Haematopoietic and lymphoid	HTK	3.6
Haematopoietic and lymphoid	HUNS1	3.9
Haematopoietic and lymphoid	HUT102	3.8
Haematopoietic and lymphoid	HUT78	3.9
Haematopoietic and lymphoid	JEKO1	3.8
Haematopoietic and lymphoid	JK1	3.8
Haematopoietic and lymphoid	JM1	3.8
Haematopoietic and lymphoid	JURKAT	3.4
Haematopoietic and lymphoid	JURLMK1	3.6
Haematopoietic and lymphoid	JVM2	3.5
Haematopoietic and lymphoid	JVM3	3.6
Haematopoietic and lymphoid	K562	3.9
Haematopoietic and lymphoid	KARPAS299	3.8
Haematopoietic and lymphoid	KARPAS422	3.9
Haematopoietic and lymphoid	KARPAS620	4.1
Haematopoietic and lymphoid	KASUMI1	4.2
Haematopoietic and lymphoid	KASUMI2	3.6
Haematopoietic and lymphoid	KASUMI6	3.4
Haematopoietic and lymphoid	KCL22	3.5
Haematopoietic and lymphoid	KE37	3.8
Haematopoietic and lymphoid	KE97	3.9
Haematopoietic and lymphoid	KG1	3.8
Haematopoietic and lymphoid	KHM1B	4
Haematopoietic and lymphoid	KIJK	3.8
Haematopoietic and lymphoid	KMH2	3.7
Haematopoietic and lymphoid	KMM1	3.8
Haematopoietic and lymphoid	KMS11	3.6
Haematopoietic and lymphoid	KMS12BM	3.5
Haematopoietic and lymphoid	KMS18	3.5
Haematopoietic and lymphoid	KMS20	3.6
Haematopoietic and lymphoid	KMS21BM	4
Haematopoietic and lymphoid	KMS26	3.7
Haematopoietic and lymphoid	KMS27	3.5
Haematopoietic and lymphoid	KMS28BM	3.8
Haematopoietic and lymphoid	KMS34	3.7
Haematopoietic and lymphoid	KO52	3.7
Haematopoietic and lymphoid	KOPN8	3.8
Haematopoietic and lymphoid	KU812	3.6
Haematopoietic and lymphoid	KYO1	3.6
Haematopoietic and lymphoid	L1236	3.6
Haematopoietic and lymphoid	L363	3.8
Haematopoietic and lymphoid	L428	3.7
Haematopoietic and lymphoid	L540	3.8
Haematopoietic and lymphoid	LAMA84	3.5
Haematopoietic and lymphoid	LOUCY	3.8
Haematopoietic and lymphoid	LP1	3.7
Haematopoietic and lymphoid	M07E	3.5
Haematopoietic and lymphoid	MC116	3.8
Haematopoietic and lymphoid	ME1	3.5
Haematopoietic and lymphoid	MEC1	3.8
Haematopoietic and lymphoid	MEC2	3.8
Haematopoietic and lymphoid	MEG01	3.8
Haematopoietic and lymphoid	MHHCALL2	3.7
Haematopoietic and lymphoid	MHHCALL3	3.7
Haematopoietic and lymphoid	MHHCALL4	3.9
Haematopoietic and lymphoid	MINO	3.6
Haematopoietic and lymphoid	MJ	3.4
Haematopoietic and lymphoid	MM1S	4.2
Haematopoietic and lymphoid	MOLM13	3.6
Haematopoietic and lymphoid	MOLM16	3.6
Haematopoietic and lymphoid	MOLM6	3.6
Haematopoietic and lymphoid	MOLP2	3.8
Haematopoietic and lymphoid	MOLP8	3.6
Haematopoietic and lymphoid	MOLT13	3.6
Haematopoietic and lymphoid	MOLT16	3.8
Haematopoietic and lymphoid	MOLT4	3.8
Haematopoietic and lymphoid	MONOMAC1	3.8
Haematopoietic and lymphoid	MONOMAC6	3.6
Haematopoietic and lymphoid	MOTN1	3.6
Haematopoietic and lymphoid	MUTZ5	3.5
Haematopoietic and lymphoid	MV411	3.4
Haematopoietic and lymphoid	NALM19	3.4
Haematopoietic and lymphoid	NALM1	3.8
Haematopoietic and lymphoid	NALM6	3.6
Haematopoietic and lymphoid	NAMALWA	3.7
Haematopoietic and lymphoid	NB4	3.4
Haematopoietic and lymphoid	NCIH929	3.9
Haematopoietic and lymphoid	NCO2	3.8
Haematopoietic and lymphoid	NOMO1	3.5
Haematopoietic and lymphoid	NUDHL1	3.8
Haematopoietic and lymphoid	NUDUL1	3.6
Haematopoietic and lymphoid	OCIAML2	3.6
Haematopoietic and lymphoid	OCIAML3	3.6
Haematopoietic and lymphoid	OCIAML5	3.5
Haematopoietic and lymphoid	OCILY10	3.7
Haematopoietic and lymphoid	OCILY19	3.6
Haematopoietic and lymphoid	OCILY3	3.4
Haematopoietic and lymphoid	OCIM1	3.5
Haematopoietic and lymphoid	OPM2	3.9
Haematopoietic and lymphoid	P12ICHIKAWA	3.7
Haematopoietic and lymphoid	P31FUJ	3.5
Haematopoietic and lymphoid	P3HR1	4
Haematopoietic and lymphoid	PCM6	3.5
Haematopoietic and lymphoid	PEER	3.6
Haematopoietic and lymphoid	PF382	3.6
Haematopoietic and lymphoid	PFEIFFER	3.6
Haematopoietic and lymphoid	PL21	3.6
Haematopoietic and lymphoid	RAJI	4.1
Haematopoietic and lymphoid	RCHACV	3.5
Haematopoietic and lymphoid	REC1	3.7
Haematopoietic and lymphoid	REH	3.8
Haematopoietic and lymphoid	RI1	3.7
Haematopoietic and lymphoid	RL	3.6
Haematopoietic and lymphoid	RPMI8226	3.6
Haematopoietic and lymphoid	RPMI8402	3.6
Haematopoietic and lymphoid	RS411	3.9
Haematopoietic and lymphoid	SEM	3.6
Haematopoietic and lymphoid	SET2	3.8
Haematopoietic and lymphoid	SIGM5	3.5
Haematopoietic and lymphoid	SKM1	3.7
Haematopoietic and lymphoid	SKMM2	3.5
Haematopoietic and lymphoid	SR786	3.5
Haematopoietic and lymphoid	ST486	3.8
Haematopoietic and lymphoid	SUDHL10	4
Haematopoietic and lymphoid	SUDHL1	3.7
Haematopoietic and lymphoid	SUDHL4	3.8
Haematopoietic and lymphoid	SUDHL5	3.6
Haematopoietic and lymphoid	SUDHL6	3.6
Haematopoietic and lymphoid	SUDHL8	3.9
Haematopoietic and lymphoid	SUPB15	3.6
Haematopoietic and lymphoid	SUPHD1	3.9
Haematopoietic and lymphoid	SUPM2	3.9
Haematopoietic and lymphoid	SUPT11	3.4
Haematopoietic and lymphoid	SUPT1	3.8
Haematopoietic and lymphoid	TALL1	3.7
Haematopoietic and lymphoid	TF1	3.8
Haematopoietic and lymphoid	THP1	3.9
Haematopoietic and lymphoid	TO175T	3.9
Haematopoietic and lymphoid	TOLEDO	3.7
Haematopoietic and lymphoid	U266B1	3.9
Haematopoietic and lymphoid	U937	3.6
Haematopoietic and lymphoid	UT7	3.6
Haematopoietic and lymphoid	WSUDLCL2	3.8
Kidney	769P	3.7
Kidney	786O	3.7
Kidney	A498	3.8
Kidney	A704	3.7
Kidney	ACHN	3.5
Kidney	BFTC909	3.4
Kidney	CAKI1	3.7
Kidney	CAKI2	3.8
Kidney	CAL54	3.6
Kidney	KMRC1	3.5
Kidney	KMRC20	3.8
Kidney	KMRC2	3.6
Kidney	KMRC3	3.6
Kidney	OSRC2	3.8
Kidney	RCC10RGB	3.6
Kidney	SNU1272	3.6
Kidney	SNU349	3.8
Kidney	TUHR10TKB	3.6
Kidney	TUHR14TKB	3.8
Kidney	TUHR4TKB	3.7
Kidney	VMRCRCW	3.7
Kidney	VMRCRCZ	3.8
Large intestine	C2BBE1	3.6
Large intestine	CCK81	3.6
Large intestine	CL11	3.4
Large intestine	CL14	3.5
Large intestine	CL34	3.6
Large intestine	CL40	3.6
Large intestine	COLO205	3.6
Large intestine	COLO320	3.6
Large intestine	COLO678	3.4
Large intestine	CW2	3.7
Large intestine	DLD1	3.8
Large intestine	GP2D	3.5
Large intestine	HCC56	3.6
Large intestine	HCT116	3.5
Large intestine	HCT15	3.8
Large intestine	HS675T	3.9
Large intestine	HS698T	3.5
Large intestine	HT115	3.6
Large intestine	HT29	3.7
Large intestine	HT55	3.6
Large intestine	KM12	3.7
Large intestine	LOVO	3.4
Large intestine	LS1034	3.7
Large intestine	LS123	3.6
Large intestine	LS180	3.6
Large intestine	LS411N	3.7
Large intestine	LS513	4
Large intestine	MDST8	3.7
Large intestine	NCIH508	4
Large intestine	NCIH716	3.6
Large intestine	NCIH747	3.6
Large intestine	OUMS23	3.6
Large intestine	RCM1	3.7
Large intestine	RKO	3.8
Large intestine	SKCO1	3.6
Large intestine	SNU1040	4.1
Large intestine	SNU1197	3.5
Large intestine	SNU175	3.7
Large intestine	SNU283	3.7
Large intestine	SNU407	3.6
Large intestine	SNU503	3.6
Large intestine	SNU61	3.7
Large intestine	SNU81	3.4
Large intestine	SNUC1	3.4
Large intestine	SNUC2A	3.8
Large intestine	SNUC4	3.5
Large intestine	SNUC5	3.6
Large intestine	SW1116	3.7
Large intestine	SW1417	3.7
Large intestine	SW1463	3.6
Large intestine	SW403	3.5
Large intestine	SW480	4
Large intestine	SW48	3.7
Large intestine	SW620	3.7
Large intestine	SW837	3.8
Large intestine	SW948	3.5
Large intestine	T84	3.6
Liver	ALEXANDERCELLS	4.1
Liver	C3A	4
Liver	HEP3B217	3.9
Liver	HEPG2	3.5
Liver	HLE	3.9
Liver	HLF	3.6
Liver	HUH1	3.9
Liver	HUH6	3.7
Liver	HUH7	3.5
Liver	JHH1	3.8
Liver	JHH2	3.4
Liver	JHH4	3.8
Liver	JHH5	3.6
Liver	JHH6	3.6
Liver	JHH7	3.7
Liver	LI7	3.4
Liver	PLCPRF5	3.6
Liver	SKHEP1	3.9
Liver	SNU182	3.4
Liver	SNU387	3.7
Liver	SNU398	3.6
Liver	SNU423	3.6
Liver	SNU449	3.6
Liver	SNU475	3.5
Liver	SNU761	3.3
Liver	SNU878	4.1
Liver	SNU886	3.4
Lung	A549	3.6
Lung	ABC1	3.6
Lung	BEN	3.7
Lung	CAL12T	3.9
Lung	CALU1	3.7
Lung	CALU3	3.7
Lung	CALU6	3.7
Lung	CHAGOK1	4
Lung	COLO668	3.7
Lung	COLO699	3.4
Lung	CORL105	3.5
Lung	CORL23	3.5
Lung	CORL24	3.5
Lung	CORL279	3.3
Lung	CORL311	3.7
Lung	CORL47	3.8
Lung	CORL51	3.5
Lung	CORL88	3.8
Lung	CORL95	3.6
Lung	CPCN	3.6
Lung	DMS114	3.5
Lung	DMS153	3.5
Lung	DMS273	3.6
Lung	DMS454	3.6
Lung	DMS53	3.5
Lung	DMS79	3.5
Lung	DV90	3.5
Lung	EBC1	3.4
Lung	EPLC272H	3.8
Lung	HARA	3.6
Lung	HCC1171	3.4
Lung	HCC1195	4
Lung	HCC15	3.8
Lung	HCC2279	3.7
Lung	HCC2935	3.3
Lung	HCC33	3.4
Lung	HCC366	3.9
Lung	HCC4006	3.6
Lung	HCC44	3.9
Lung	HCC78	3.6
Lung	HCC827	3.7
Lung	HCC95	3.7
Lung	HLC1	3.6
Lung	HLFA	3.5
Lung	HS229T	3.6
Lung	HS618T	3.6
Lung	IALM	3.8
Lung	KNS62	3.8
Lung	LC1F	3.9
Lung	LC1SQSF	4.1
Lung	LCLC103H	3.3
Lung	LCLC97TM1	3.7
Lung	LK2	3.7
Lung	LOUNH91	3.8
Lung	LU65	4
Lung	LU99	3.7
Lung	LUDLU1	3.8
Lung	LXF289	3.4
Lung	MORCPR	3.8
Lung	NCIH1048	3.5
Lung	NCIH1092	3.7
Lung	NCIH1105	3.6
Lung	NCIH1155	3.5
Lung	NCIH1184	3.6
Lung	NCIH1299	3.6
Lung	NCIH1339	3.5
Lung	NCIH1341	3.5
Lung	NCIH1355	3.6
Lung	NCIH1373	3.8
Lung	NCIH1385	3.5
Lung	NCIH1395	3.5
Lung	NCIH1435	3.4
Lung	NCIH1436	3.6
Lung	NCIH1437	3.7
Lung	NCIH146	3.5
Lung	NCIH1563	3.6
Lung	NCIH1568	3.5
Lung	NCIH1573	3.6
Lung	NCIH1581	3.4
Lung	NCIH1618	3.5
Lung	NCIH1623	3.9
Lung	NCIH1648	3.4
Lung	NCIH1650	3.5
Lung	NCIH1651	3.7
Lung	NCIH1666	3.7
Lung	NCIH1693	4
Lung	NCIH1694	3.7
Lung	NCIH1703	3.5
Lung	NCIH1734	3.6
Lung	NCIH1755	3.5
Lung	NCIH1781	3.5
Lung	NCIH1792	3.7
Lung	NCIH1793	3.8
Lung	NCIH1836	3.5
Lung	NCIH1838	3.5
Lung	NCIH1869	3.5
Lung	NCIH1876	3.4
Lung	NCIH1915	3.6
Lung	NCIH1930	3.2
Lung	NCIH1944	3.6
Lung	NCIH1963	3.5
Lung	NCIH196	3.7
Lung	NCIH1975	3.6
Lung	NCIH2009	3.6
Lung	NCIH2023	3.8
Lung	NCIH2029	3.4
Lung	NCIH2030	3.7
Lung	NCIH2066	3.8
Lung	NCIH2081	3.4
Lung	NCIH2085	3.7
Lung	NCIH2087	3.5
Lung	NCIH209	3.6
Lung	NCIH2106	3.5
Lung	NCIH2110	3.9
Lung	NCIH211	3.6
Lung	NCIH2122	3.7
Lung	NCIH2126	3.5
Lung	NCIH2141	3.2
Lung	NCIH2170	3.6
Lung	NCIH2171	3.6
Lung	NCIH2172	3.9
Lung	NCIH2196	3.2
Lung	NCIH2227	3.4
Lung	NCIH2228	3.6
Lung	NCIH226	3.6
Lung	NCIH2286	3.7
Lung	NCIH2291	3.9
Lung	NCIH2342	3.9
Lung	NCIH2347	3.6
Lung	NCIH23	3.7
Lung	NCIH2405	3.6
Lung	NCIH2444	3.7
Lung	NCIH292	3.5
Lung	NCIH322	4.1
Lung	NCIH3255	3.4
Lung	NCIH358	3.9
Lung	NCIH441	3.8
Lung	NCIH446	3.6
Lung	NCIH460	3.5
Lung	NCIH510	3.4
Lung	NCIH520	3.8
Lung	NCIH522	3.4
Lung	NCIH524	3.5
Lung	NCIH526	3.5
Lung	NCIH596	3.8
Lung	NCIH647	3.6
Lung	NCIH650	3.4
Lung	NCIH661	3.6
Lung	NCIH69	3.6
Lung	NCIH727	3.5
Lung	NCIH810	3.5
Lung	NCIH82	3.4
Lung	NCIH838	3.6
Lung	NCIH841	3.6
Lung	NCIH854	3.7
Lung	NCIH889	3.7
Lung	PC14	3.6
Lung	RERFLCAD1	3.4
Lung	RERFLCAD2	3.7
Lung	RERFLCAI	3.9
Lung	RERFLCKJ	3.7
Lung	RERFLCMS	3.6
Lung	RERFLCSQ1	3.7
Lung	SBC5	3.4
Lung	SCLC21H	3.5
Lung	SHP77	3.7
Lung	SKLU1	3.8
Lung	SKMES1	3.7
Lung	SQ1	3.6
Lung	SW1271	3.5
Lung	SW1573	3.7
Lung	SW900	3.9
Lung	VMRCLCD	3.3
Lung	VMRCLCP	3.6
Oesophagus	COLO680N	3.6
Oesophagus	ECGI10	3.5
Oesophagus	KYSE140	3.6
Oesophagus	KYSE150	3.7
Oesophagus	KYSE180	3.8
Oesophagus	KYSE270	3.8
Oesophagus	KYSE30	3.5
Oesophagus	KYSE410	3.6
Oesophagus	KYSE450	3.8
Oesophagus	KYSE510	3.7
Oesophagus	KYSE520	3.8
Oesophagus	KYSE70	3.5
Oesophagus	OE19	3.9
Oesophagus	OE33	3.6
Oesophagus	TE10	3.8
Oesophagus	TE11	3.6
Oesophagus	TE14	3.5
Oesophagus	TE15	3.6
Oesophagus	TE1	3.5
Oesophagus	TE4	3.5
Oesophagus	TE5	3.5
Oesophagus	TE6	3.4
Oesophagus	TE8	3.4
Oesophagus	TE9	3.7
Oesophagus	TT	3.7
Ovary	59M	3.5
Ovary	A2780	3.5
Ovary	CAOV3	3.8
Ovary	CAOV4	3.6
Ovary	COLO704	3.4
Ovary	COV318	3.7
Ovary	COV362	3.8
Ovary	COV434	4
Ovary	COV504	3.8
Ovary	COV644	3.7
Ovary	EFO21	3.3
Ovary	EFO27	3.7
Ovary	ES2	3.7
Ovary	FUOV1	3.6
Ovary	HEYA8	4
Ovary	HS571T	3.7
Ovary	IGROV1	3.6
Ovary	JHOC5	3.7
Ovary	JHOM1	3.5
Ovary	JHOM2B	3.4
Ovary	JHOS2	3.4
Ovary	JHOS4	3.8
Ovary	KURAMOCHI	3.5
Ovary	MCAS	3.7
Ovary	NIHOVCAR3	3.6
Ovary	OAW28	4
Ovary	OAW42	3.6
Ovary	OC314	3.6
Ovary	OC316	3.6
Ovary	ONCODG1	3.5
Ovary	OV56	3.9
Ovary	OV7	3.6
Ovary	OV90	3.8
Ovary	OVCAR4	3.5
Ovary	OVCAR8	4.1
Ovary	OVISE	3.6
Ovary	OVK18	3.5
Ovary	OVKATE	3.6
Ovary	OVMANA	3.7
Ovary	OVSAHO	3.4
Ovary	OVTOKO	3.8
Ovary	RMGI	3.7
Ovary	RMUGS	4
Ovary	SKOV3	3.5
Ovary	SNU119	3.4
Ovary	SNU840	3.7
Ovary	SNU8	4.1
Ovary	TOV112D	3.6
Ovary	TOV21G	3.6
Ovary	TYKNU	3.5
Pancreas	ASPC1	3.7
Pancreas	BXPC3	3.6
Pancreas	CAPAN1	3.3
Pancreas	CAPAN2	4
Pancreas	CFPAC1	3.4
Pancreas	DANG	3.5
Pancreas	HPAC	3.6
Pancreas	HPAFII	3.5
Pancreas	HS766T	3.7
Pancreas	HUPT3	3.5
Pancreas	HUPT4	3.7
Pancreas	KCIMOH1	3.8
Pancreas	KLM1	3.5
Pancreas	KP2	3.6
Pancreas	KP3	3.7
Pancreas	KP4	3.5
Pancreas	L33	3.9
Pancreas	MIAPACA2	3.9
Pancreas	PANC0203	3.6
Pancreas	PANC0213	3.5
Pancreas	PANC0327	3.5
Pancreas	PANC0403	3.7
Pancreas	PANC0504	3.5
Pancreas	PANC0813	3.5
Pancreas	PANC1005	3.7
Pancreas	PANC1	4
Pancreas	PATU8902	3.6
Pancreas	PATU8988S	3.6
Pancreas	PATU8988T	3.6
Pancreas	PK1	3.8
Pancreas	PK45H	3.7
Pancreas	PK59	3.5
Pancreas	PL45	3.7
Pancreas	PSN1	3.6
Pancreas	QGP1	3.6
Pancreas	SNU213	3.5
Pancreas	SNU324	3.6
Pancreas	SNU410	3.7
Pancreas	SU8686	3.6
Pancreas	SUIT2	4
Pancreas	SW1990	3.7
Pancreas	T3M4	4.1
Pancreas	TCCPAN2	3.5
Pancreas	YAPC	3.6
Pleura	ACCMESO1	3.5
Pleura	DM3	3.6
Pleura	ISTMES1	3.6
Pleura	ISTMES2	3.6
Pleura	JL1	3.4
Pleura	MPP89	3.6
Pleura	MSTO211H	3.7
Pleura	NCIH2052	3.4
Pleura	NCIH2452	3.8
Pleura	NCIH28	3.8
Prostate	22RV1	3.4
Prostate	DU145	3.7
Prostate	LNCAPCLONEFGC	3.5
Prostate	MDAPCA2B	3.5
Prostate	NCIH660	3.6
Prostate	PC3	3.6
Prostate	VCAP	3.5
Salivary gland	A253	3.7
Salivary gland	YD15	3.7
Skin	A101D	3.7
Skin	A2058	3.4
Skin	A375	3.6
Skin	C32	3.4
Skin	CHL1	3.4
Skin	CJM	3.6
Skin	COLO679	3.5
Skin	COLO741	3.5
Skin	COLO783	3.7
Skin	COLO792	4
Skin	COLO800	3.8
Skin	COLO818	3.8
Skin	COLO829	3.4
Skin	COLO849	3.5
Skin	G361	3.5
Skin	GRM	3.5
Skin	HMCB	3.4
Skin	HS294T	3.7
Skin	HS600T	3.7
Skin	HS688AT	3.6
Skin	HS695T	3.8
Skin	HS839T	3.7
Skin	HS852T	3.7
Skin	HS895T	3.8
Skin	HS934T	3.7
Skin	HS936T	3.8
Skin	HS939T	3.5
Skin	HS940T	3.8
Skin	HS944T	3.8
Skin	HT144	3.7
Skin	IGR1	3.8
Skin	IGR37	3.6
Skin	IGR39	3.5
Skin	IPC298	3.7
Skin	K029AX	3.4
Skin	LOXIMVI	3.6
Skin	MALME3M	3.7
Skin	MDAMB435S	3.5
Skin	MELHO	3.7
Skin	MELJUSO	3.8
Skin	MEWO	3.6
Skin	RPMI7951	3.5
Skin	RVH421	3.8
Skin	SH4	3.5
Skin	SKMEL1	3.7
Skin	SKMEL24	3.4
Skin	SKMEL28	3.4
Skin	SKMEL2	3.5
Skin	SKMEL30	3.7
Skin	SKMEL31	3.7
Skin	SKMEL3	3.6
Skin	SKMEL5	3.8
Skin	UACC257	3.8
Skin	UACC62	3.8
Skin	WM115	3.5
Skin	WM1799	3.5
Skin	WM2664	3.5
Skin	WM793	3.6
Skin	WM88	3.6
Skin	WM983B	3.9
Small intestine	HUTU80	3.7
Soft tissue	A204	3.7
Soft tissue	G401	3.6
Soft tissue	G402	3.9
Soft tissue	GCT	3.7
Soft tissue	HS729	3.6
Soft tissue	HT1080	3.6
Soft tissue	KYM1	3.9
Soft tissue	MESSA	3.5
Soft tissue	RD	3.5
Soft tissue	RH30	3.6
Soft tissue	RH41	3.5
Soft tissue	RKN	3.7
Soft tissue	S117	3.5
Soft tissue	SJRH30	3.8
Soft tissue	SKLMS1	3.6
Soft tissue	SKUT1	3.7
Soft tissue	TE125T	3.4
Soft tissue	TE159T	3.6
Soft tissue	TE441T	3.7
Soft tissue	TE617T	3.7
Stomach	2313287	3.7
Stomach	AGS	3.7
Stomach	AZ521	3.4
Stomach	ECC10	3.2
Stomach	ECC12	3.3
Stomach	FU97	3.8
Stomach	GCIY	3.4
Stomach	GSS	3.4
Stomach	GSU	3.5
Stomach	HGC27	3.7
Stomach	HS746T	3.5
Stomach	HUG1N	3.7
Stomach	IM95	3.6
Stomach	KATOIII	3.8
Stomach	KE39	4
Stomach	LMSU	3.6
Stomach	MKN1	3.4
Stomach	MKN45	3.7
Stomach	MKN74	3.7
Stomach	MKN7	3.6
Stomach	NCCSTCK140	3.6
Stomach	NCIN87	3.6
Stomach	NUGC2	3.5
Stomach	NUGC3	3.9
Stomach	NUGC4	3.7
Stomach	OCUM1	3.6
Stomach	RERFGC1B	3.7
Stomach	SH10TC	3.6
Stomach	SNU16	3.6
Stomach	SNU1	3.6
Stomach	SNU216	3.5
Stomach	SNU520	3.8
Stomach	SNU5	4.1
Stomach	SNU601	3.4
Stomach	SNU620	3.6
Stomach	SNU668	3.7
Stomach	SNU719	3.4
Stomach	TGBC11TKB	3.5
Thyroid	8305C	3.6
Thyroid	8505C	3.5
Thyroid	BCPAP	3.5
Thyroid	BHT101	3.6
Thyroid	CAL62	3.5
Thyroid	CGTHW1	3.5
Thyroid	FTC133	3.6
Thyroid	FTC238	3.6
Thyroid	ML1	3.5
Thyroid	SW579	3.7
Thyroid	TT2609C02	3.4
Thyroid	TT	3.4
Upper aerodigestive tract	BHY	3.6
Upper aerodigestive tract	BICR16	3.7
Upper aerodigestive tract	BICR18	3.6
Upper aerodigestive tract	BICR22	3.7
Upper aerodigestive tract	BICR31	4
Upper aerodigestive tract	BICR56	3.5
Upper aerodigestive tract	BICR6	3.7
Upper aerodigestive tract	CAL27	3.9
Upper aerodigestive tract	CAL33	3.5
Upper aerodigestive tract	DETROIT562	3.5
Upper aerodigestive tract	FADU	3.9
Upper aerodigestive tract	HS840T	3.8
Upper aerodigestive tract	HSC2	3.7
Upper aerodigestive tract	HSC3	3.9
Upper aerodigestive tract	HSC4	3.5
Upper aerodigestive tract	PECAPJ15	3.6
Upper aerodigestive tract	PECAPJ34CLONEC12	3.6
Upper aerodigestive tract	PECAPJ41CLONED2	3.7
Upper aerodigestive tract	PECAPJ49	3.6
Upper aerodigestive tract	SCC15	3.6
Upper aerodigestive tract	SCC25	3.9
Upper aerodigestive tract	SCC4	3.8
Upper aerodigestive tract	SCC9	3.6
Upper aerodigestive tract	SNU1076	3.7
Upper aerodigestive tract	SNU1214	3.4
Upper aerodigestive tract	SNU46	3.6
Upper aerodigestive tract	SNU899	3.6
Upper aerodigestive tract	YD10B	3.6
Upper aerodigestive tract	YD38	3.8
Upper aerodigestive tract	YD8	3.6
Urinary tract	5637	3.9
Urinary tract	639V	3.9
Urinary tract	647V	3.7
Urinary tract	BC3C	3.5
Urinary tract	BFTC905	3.5
Urinary tract	CAL29	3.7
Urinary tract	HS172T	3.2
Urinary tract	HT1197	4.1
Urinary tract	HT1376	3.6
Urinary tract	J82	3.9
Urinary tract	JMSU1	3.3
Urinary tract	KMBC2	3.6
Urinary tract	KU1919	3.5
Urinary tract	RT11284	3.7
Urinary tract	RT112	3.7
Urinary tract	RT4	3.7
Urinary tract	SCABER	3.8
Urinary tract	SW1710	3.7
Urinary tract	SW780	3.6
Urinary tract	T24	3.6
Urinary tract	TCCSUP	3.4
Urinary tract	UMUC1	3.4
Urinary tract	UMUC3	3.7
Urinary tract	VMCUB1	3.7

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	0
Adrenal gland	0
Appendix	0
Bone marrow	0.6
Breast	0.1
Cerebral cortex	0.3
Cervix, uterine	0
Colon	0
Duodenum	0
Endometrium	0.2
Epididymis	4.3
Esophagus	0
Fallopian tube	0.3
Gallbladder	0.1
Heart muscle	0
Kidney	0.2
Liver	0
Lung	0
Lymph node	0.2
Ovary	0.1
Pancreas	0.1
Parathyroid gland	0
Placenta	0.2
Prostate	0.1
Rectum	0.1
Salivary gland	0
Seminal vesicle	0.2
Skeletal muscle	0
Skin	0.3
Small intestine	0
Smooth muscle	0
Spleen	0.3
Stomach	0.1
Testis	7.7
Thyroid gland	0.3
Tonsil	0.1
Urinary bladder	0

> Text Mining based Expression [ TOP ]
There is no record.

Summary
Symbol	PRDM9
Name	PR/SET domain 9
Aliases	PFM6; ZNF899; PR-domain containing protein 9; MSBP3; minisatellite binding protein 3, 115kDa; minisatellite ......
Location	5p14.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

Summary
Symbol	PRDM9
Name	PR/SET domain 9
Aliases	PFM6; ZNF899; PR-domain containing protein 9; MSBP3; minisatellite binding protein 3, 115kDa; minisatellite ......
Location	5p14.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR [ TOP ]
There is no record.

Summary
Symbol	PRDM9
Name	PR/SET domain 9
Aliases	PFM6; ZNF899; PR-domain containing protein 9; MSBP3; minisatellite binding protein 3, 115kDa; minisatellite ......
Location	5p14.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA) [ TOP ]
There is no antibody staining data.

Summary
Symbol	PRDM9
Name	PR/SET domain 9
Aliases	PFM6; ZNF899; PR-domain containing protein 9; MSBP3; minisatellite binding protein 3, 115kDa; minisatellite ......
Location	5p14.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype [ TOP ]
There is no record.

> Overall survival [ TOP ]
There is no data.

> Stage [ TOP ]
There is no data.

> Grade [ TOP ]
There is no data.

Summary
Symbol	PRDM9
Name	PR/SET domain 9
Aliases	PFM6; ZNF899; PR-domain containing protein 9; MSBP3; minisatellite binding protein 3, 115kDa; minisatellite ......
Location	5p14.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	PRDM9
Name	PR/SET domain 9
Aliases	PFM6; ZNF899; PR-domain containing protein 9; MSBP3; minisatellite binding protein 3, 115kDa; minisatellite ......
Location	5p14.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for PRDM9.

Summary
Symbol	PRDM9
Name	PR/SET domain 9
Aliases	PFM6; ZNF899; PR-domain containing protein 9; MSBP3; minisatellite binding protein 3, 115kDa; minisatellite ......
Location	5p14.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]
There is no record for PRDM9.

> Interactions from Text Mining [ TOP ]
There is no record for PRDM9.