Browse SETD7 in pancancer

Summary
SymbolSETD7
NameSET domain containing lysine methyltransferase 7
Aliases KIAA1717; SET7/9; Set9; KMT7; H3-K4-HMTase SETD7; SET domain-containing protein 7; histone H3-K4 methyltrans ......
Location4q31.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Domain, Function and Classification
> Gene Ontology
> KEGG and Reactome Pathway
> Domain, Function and Classification
 
Domain PF02493 MORN repeat
PF00856 SET domain
Function

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.

Classification
Class Modification Substrate Product PubMed
Histone modification write Histone methylation H3K4 H3K4me1 11779497
> Gene Ontology
 
Biological Process GO:0006479 protein methylation
GO:0008213 protein alkylation
GO:0016570 histone modification
GO:0016571 histone methylation
GO:0018022 peptidyl-lysine methylation
GO:0018026 peptidyl-lysine monomethylation
GO:0018027 peptidyl-lysine dimethylation
GO:0018205 peptidyl-lysine modification
GO:0031056 regulation of histone modification
GO:0031060 regulation of histone methylation
GO:0032259 methylation
GO:0034968 histone lysine methylation
GO:0043414 macromolecule methylation
GO:0045471 response to ethanol
GO:0051567 histone H3-K9 methylation
GO:0051570 regulation of histone H3-K9 methylation
GO:0061647 histone H3-K9 modification
GO:0070828 heterochromatin organization
GO:0097305 response to alcohol
GO:1902275 regulation of chromatin organization
Molecular Function GO:0002039 p53 binding
GO:0003682 chromatin binding
GO:0008168 methyltransferase activity
GO:0008170 N-methyltransferase activity
GO:0008276 protein methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0016278 lysine N-methyltransferase activity
GO:0016279 protein-lysine N-methyltransferase activity
GO:0016741 transferase activity, transferring one-carbon groups
GO:0018024 histone-lysine N-methyltransferase activity
GO:0042054 histone methyltransferase activity
Cellular Component -
> KEGG and Reactome Pathway
 
KEGG hsa04068 FoxO signaling pathway
hsa00310 Lysine degradation
Reactome R-HSA-3247509: Chromatin modifying enzymes
R-HSA-4839726: Chromatin organization
R-HSA-3214841: PKMTs methylate histone lysines
Summary
SymbolSETD7
NameSET domain containing lysine methyltransferase 7
Aliases KIAA1717; SET7/9; Set9; KMT7; H3-K4-HMTase SETD7; SET domain-containing protein 7; histone H3-K4 methyltrans ......
Location4q31.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Mutation landscape in primary tumor tissue from TCGA
> Mutation landscape in cancer cell line from CCLE
> All mutations from COSMIC database V81
> Variations from text mining
> The Cancer Genome Atlas (TCGA)
 
> Cancer Cell Line Encyclopedia (CCLE)
 
There is no record.
> Catalogue of Somatic Mutations in Cancer (COSMIC)
 
COSMIC ID CDS change AA change Mutation Type Anatomical Site
COSM1567000c.1026delCp.K344fs*14Deletion - FrameshiftLarge_intestine
COSM3718642c.1038G>Tp.G346GSubstitution - coding silentUpper_aerodigestive_tract
COSM3917188c.783C>Tp.A261ASubstitution - coding silentBone
COSM3767703c.935G>Cp.R312PSubstitution - MissenseLiver
COSM4584792c.212A>Gp.Q71RSubstitution - MissenseBone
COSM1051395c.170G>Tp.S57ISubstitution - MissenseEndometrium
COSM5356238c.727T>Cp.S243PSubstitution - MissenseLarge_intestine
COSM4122411c.201C>Ap.A67ASubstitution - coding silentStomach
COSM3917188c.783C>Tp.A261ASubstitution - coding silentSkin
COSM4628254c.193G>Ap.D65NSubstitution - MissenseLarge_intestine
COSM337127c.607A>Tp.T203SSubstitution - MissenseLung
COSM4957405c.790G>Cp.G264RSubstitution - MissenseLiver
COSM1225387c.7A>Cp.S3RSubstitution - MissenseLarge_intestine
COSM5952343c.170+9C>Tp.?UnknownOesophagus
COSM5908434c.645-8C>Tp.?UnknownSkin
COSM3718642c.1038G>Tp.G346GSubstitution - coding silentUpper_aerodigestive_tract
COSM1427200c.460G>Ap.A154TSubstitution - MissenseLarge_intestine
COSM4957405c.790G>Cp.G264RSubstitution - MissenseLiver
COSM4442170c.361A>Tp.I121LSubstitution - MissenseLarge_intestine
COSM1051394c.419C>Ap.T140NSubstitution - MissenseEndometrium
COSM1051393c.644+2T>Gp.?UnknownEndometrium
COSM5574966c.143G>Ap.R48QSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM375335c.640G>Ap.E214KSubstitution - MissenseLung
COSM1051390c.959G>Ap.R320HSubstitution - MissenseLarge_intestine
COSM4615728c.1026_1027insCp.G343fs*6Insertion - FrameshiftLarge_intestine
COSM4636465c.1027G>Ap.G343RSubstitution - MissenseLarge_intestine
COSM4456792c.1021C>Tp.P341SSubstitution - MissenseSkin
COSM4644583c.264C>Tp.D88DSubstitution - coding silentLarge_intestine
COSM3669244c.1045G>Ap.A349TSubstitution - MissenseLiver
COSM1051392c.746G>Ap.R249QSubstitution - MissenseLarge_intestine
COSM3825233c.52G>Ap.D18NSubstitution - MissenseBreast
COSM5991765c.363_366delATATp.Y122fs*8Deletion - FrameshiftProstate
COSM5991765c.363_366delATATp.Y122fs*8Deletion - FrameshiftProstate
COSM1618419c.142C>Tp.R48WSubstitution - MissenseLiver
COSM1485689c.223A>Tp.T75SSubstitution - MissenseBreast
COSM5995402c.748A>Tp.I250FSubstitution - MissenseProstate
COSM4512443c.902C>Tp.P301LSubstitution - MissenseSkin
COSM3600408c.566C>Tp.S189LSubstitution - MissenseSkin
COSM5634373c.792G>Cp.G264GSubstitution - coding silentOesophagus
COSM3600407c.928C>Tp.H310YSubstitution - MissenseSkin
COSM3946003c.324G>Ap.G108GSubstitution - coding silentLung
COSM5995401c.981C>Tp.A327ASubstitution - coding silentProstate
COSM3917187c.933C>Tp.P311PSubstitution - coding silentSkin
COSM76390c.1028G>Tp.G343VSubstitution - MissenseOvary
COSM5551816c.625G>Tp.D209YSubstitution - MissenseProstate
COSM1618419c.142C>Tp.R48WSubstitution - MissenseLiver
COSM4138052c.801C>Gp.L267LSubstitution - coding silentOvary
COSM1051391c.934C>Tp.R312CSubstitution - MissenseEndometrium
COSM3825231c.1080C>Tp.F360FSubstitution - coding silentBreast
COSM1051390c.959G>Ap.R320HSubstitution - MissenseEndometrium
COSM4457284c.1039C>Tp.P347SSubstitution - MissenseSkin
COSM1265351c.1046C>Tp.A349VSubstitution - MissenseOesophagus
COSM1427199c.477T>Gp.F159LSubstitution - MissenseLarge_intestine
COSM4122410c.491T>Cp.M164TSubstitution - MissenseStomach
COSM4628255c.65C>Tp.P22LSubstitution - MissenseLarge_intestine
COSM1427200c.460G>Ap.A154TSubstitution - MissenseLarge_intestine
COSM3696449c.438T>Cp.Y146YSubstitution - coding silentLarge_intestine
COSM1051392c.746G>Ap.R249QSubstitution - MissenseEndometrium
COSM4636465c.1027G>Ap.G343RSubstitution - MissenseLarge_intestine
COSM362303c.250G>Tp.G84CSubstitution - MissenseLung
COSM1265350c.1044A>Cp.E348DSubstitution - MissenseOesophagus
COSM3414471c.997G>Ap.V333ISubstitution - MissenseOesophagus
COSM3825232c.127G>Ap.G43RSubstitution - MissenseStomach
COSM5995401c.981C>Tp.A327ASubstitution - coding silentProstate
COSM4777770c.1019_1020insCp.G343fs*6Insertion - FrameshiftProstate
COSM5574966c.143G>Ap.R48QSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM5060138c.764T>Cp.V255ASubstitution - MissenseStomach
COSM4773008c.574C>Ap.H192NSubstitution - MissenseStomach
COSM1051391c.934C>Tp.R312CSubstitution - MissenseEndometrium
COSM5991765c.363_366delATATp.Y122fs*8Deletion - FrameshiftProstate
COSM5463315c.352G>Ap.V118MSubstitution - MissenseLarge_intestine
COSM1495757c.592T>Cp.S198PSubstitution - MissenseKidney
COSM1186663c.304G>Tp.G102WSubstitution - MissenseLung
COSM126107c.1030A>Gp.K344ESubstitution - MissenseUpper_aerodigestive_tract
COSM5890051c.739G>Ap.G247RSubstitution - MissenseSkin
COSM1225385c.763-2A>Gp.?UnknownLarge_intestine
COSM5995401c.981C>Tp.A327ASubstitution - coding silentProstate
COSM1633461c.684A>Gp.E228ESubstitution - coding silentLiver
COSM40582c.916G>Ap.D306NSubstitution - MissenseCentral_nervous_system
COSM1225386c.209G>Ap.G70DSubstitution - MissenseLarge_intestine
COSM5904797c.1015C>Tp.H339YSubstitution - MissenseSkin
COSM1427200c.460G>Ap.A154TSubstitution - MissenseLarge_intestine
COSM5617203c.927C>Tp.V309VSubstitution - coding silentLung
COSM292454c.874G>Tp.G292*Substitution - NonsenseLarge_intestine
COSM3825232c.127G>Ap.G43RSubstitution - MissenseBreast
COSM3414471c.997G>Ap.V333ISubstitution - MissenseOesophagus
COSM3669244c.1045G>Ap.A349TSubstitution - MissenseLiver
COSM5654722c.63A>Gp.L21LSubstitution - coding silentHaematopoietic_and_lymphoid_tissue
COSM3767704c.542A>Gp.H181RSubstitution - MissenseLiver
COSM1051391c.934C>Tp.R312CSubstitution - MissenseEndometrium
COSM4625231c.1028G>Ap.G343ESubstitution - MissenseLarge_intestine
COSM447400c.373G>Ap.D125NSubstitution - MissenseBreast
> Text Mining based Variations
 
PMID Variation Cancer Evidence
25189356mutationProstate CarcinomaFrom this genome-wide approach, mutations were found in a series of genes with prostate cancer relevance, including AR, NCOR1, KDM3A, KDM4A, CHD1, SETD5, SETD7, INPP4B, RASGRP3, RASA1, TP53BP1, and CDH1, and a novel SND1:BRAF gene fusion.
Summary
SymbolSETD7
NameSET domain containing lysine methyltransferase 7
Aliases KIAA1717; SET7/9; Set9; KMT7; H3-K4-HMTase SETD7; SET domain-containing protein 7; histone H3-K4 methyltrans ......
Location4q31.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Post-translational modification (PTM)
> Post-translational modification (PTM)
 
There is no PTM data
Summary
SymbolSETD7
NameSET domain containing lysine methyltransferase 7
Aliases KIAA1717; SET7/9; Set9; KMT7; H3-K4-HMTase SETD7; SET domain-containing protein 7; histone H3-K4 methyltrans ......
Location4q31.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Expression analysis in primary tumor tissue from TCGA
> Expression level in cancer cell line from CCLE
> Expression level in human normal tissue from HPA
> Text mining based expression change
> The Cancer Genome Atlas (TCGA)
 


  Differential expression analysis for cancers with more than 10 normal samples
Cancer Full Name # N # T Median (N) Median (T) LogFC Adj. P Status
BLCABladder urothelial carcinoma194086.8415.785-1.1322.13e-09Under
BRCABreast invasive carcinoma11211007.616.929-0.9175.13e-30Under
CESCCervical and endocervical cancers33066.9945.775NANANA
COADColon adenocarcinoma414595.7716.2540.2150.0485NS
ESCAEsophageal carcinoma111857.2666.823-0.630.00413Under
GBMGlioblastoma multiforme51666.5396.279NANANA
HNSCHead and Neck squamous cell carcinoma445226.5996.193-0.4820.000105NS
KIRCKidney renal clear cell carcinoma725346.1966.8730.64.12e-13Over
KIRPKidney renal papillary cell carcinoma322915.7236.10.2790.0573NS
LAMLAcute Myeloid Leukemia0173NA5.45NANANA
LGGBrain Lower Grade Glioma0530NA6.843NANANA
LIHCLiver hepatocellular carcinoma503736.7496.162-0.6381.26e-06Under
LUADLung adenocarcinoma595176.6866.696-0.0750.435NS
LUSCLung squamous cell carcinoma515016.7136.239-0.4852.16e-06NS
OVOvarian serous cystadenocarcinoma0307NA5.129NANANA
PAADPancreatic adenocarcinoma41796.4096.379NANANA
PCPGPheochromocytoma and Paraganglioma31846.4816.221NANANA
PRADProstate adenocarcinoma524987.5727.5520.0960.334NS
READRectum adenocarcinoma101676.4036.053-0.4640.0269NS
SARCSarcoma22636.286.597NANANA
SKCMSkin Cutaneous Melanoma14724.9685.579NANANA
STADStomach adenocarcinoma354156.7596.67-0.3410.0358NS
TGCTTesticular Germ Cell Tumors0156NA3.82NANANA
THCAThyroid carcinoma595095.5575.720.1680.0904NS
THYMThymoma21206.0285.198NANANA
UCECUterine Corpus Endometrial Carcinoma355467.1574.629-2.4553.88e-33Under
> Cancer Cell Line Encyclopedia (CCLE)
 



Tissue Cell Line Expression Level (Microarray)
Autonomic ganglia CHP126 10.7
Autonomic ganglia CHP212 9.8
Autonomic ganglia IMR32 10
Autonomic ganglia KELLY 9.6
Autonomic ganglia KPNRTBM1 10.7
Autonomic ganglia KPNSI9S 9.9
Autonomic ganglia KPNYN 10.3
Autonomic ganglia MHHNB11 9.5
Autonomic ganglia NB1 10.3
Autonomic ganglia NH6 10
Autonomic ganglia SHSY5Y 9.1
Autonomic ganglia SIMA 9.8
Autonomic ganglia SKNAS 10.3
Autonomic ganglia SKNBE2 10.5
Autonomic ganglia SKNDZ 9
Autonomic ganglia SKNFI 10.5
Autonomic ganglia SKNSH 9.8
Biliary tract HUCCT1 10.3
Biliary tract HUH28 9.8
Biliary tract SNU1079 9.9
Biliary tract SNU1196 10.6
Biliary tract SNU245 9.8
Biliary tract SNU308 9.8
Biliary tract SNU478 10.4
Bone 143B 10.3
Bone A673 10.6
Bone CADOES1 8.2
Bone CAL78 11
Bone G292CLONEA141B1 9.8
Bone HOS 10.5
Bone HS706T 10.8
Bone HS737T 11
Bone HS819T 11
Bone HS821T 11.5
Bone HS822T 10.9
Bone HS863T 11.3
Bone HS870T 10.8
Bone HS888T 10.7
Bone MG63 9.6
Bone MHHES1 11.1
Bone OUMS27 9.6
Bone RDES 8.8
Bone SJSA1 9
Bone SKES1 9.9
Bone SKNMC 10.6
Bone SW1353 10.5
Bone T173 11.2
Bone TC71 10.3
Bone U2OS 9.7
Breast AU565 11
Breast BT20 10.7
Breast BT474 10.6
Breast BT483 10.5
Breast BT549 8.3
Breast CAL120 9.9
Breast CAL148 10.3
Breast CAL51 8.5
Breast CAL851 9.4
Breast CAMA1 10.7
Breast DU4475 9.1
Breast EFM192A 10.6
Breast EFM19 8.7
Breast EVSAT 11
Breast HCC1143 9.8
Breast HCC1187 9.6
Breast HCC1395 10.5
Breast HCC1419 11.3
Breast HCC1428 10.9
Breast HCC1500 10.2
Breast HCC1569 9.2
Breast HCC1599 10.1
Breast HCC1806 9.4
Breast HCC1937 10.6
Breast HCC1954 10.5
Breast HCC202 10.6
Breast HCC2157 9.2
Breast HCC2218 10.8
Breast HCC38 10.5
Breast HCC70 10
Breast HDQP1 9.6
Breast HMC18 10.3
Breast HS274T 11.4
Breast HS281T 11.2
Breast HS343T 11.3
Breast HS578T 10.3
Breast HS606T 10.9
Breast HS739T 11
Breast HS742T 11.7
Breast JIMT1 10.1
Breast KPL1 10.8
Breast MCF7 10.8
Breast MDAMB134VI 8.9
Breast MDAMB157 9.3
Breast MDAMB175VII 10.5
Breast MDAMB231 10.5
Breast MDAMB361 11.3
Breast MDAMB415 9.5
Breast MDAMB436 11
Breast MDAMB453 10.8
Breast MDAMB468 9.8
Breast SKBR3 10.8
Breast T47D 10
Breast UACC812 9.7
Breast UACC893 11.3
Breast YMB1 11.3
Breast ZR751 10.5
Breast ZR7530 10.8
Central nervous system 1321N1 9.6
Central nervous system 42MGBA 9.9
Central nervous system 8MGBA 9.9
Central nervous system A172 10.5
Central nervous system AM38 10.7
Central nervous system BECKER 9.9
Central nervous system CAS1 9.7
Central nervous system CCFSTTG1 10
Central nervous system D283MED 11.8
Central nervous system D341MED 12.5
Central nervous system DAOY 9.4
Central nervous system DBTRG05MG 10.1
Central nervous system DKMG 10.6
Central nervous system GAMG 10.1
Central nervous system GB1 8.9
Central nervous system GI1 8.8
Central nervous system GMS10 10.1
Central nervous system GOS3 12
Central nervous system H4 10.6
Central nervous system HS683 9.8
Central nervous system KALS1 9.5
Central nervous system KG1C 9.8
Central nervous system KNS42 11.3
Central nervous system KNS60 9.8
Central nervous system KNS81 10.5
Central nervous system KS1 10.3
Central nervous system LN18 9.7
Central nervous system LN229 10.1
Central nervous system M059K 10.1
Central nervous system MOGGCCM 9.1
Central nervous system MOGGUVW 10.5
Central nervous system NMCG1 10.1
Central nervous system ONS76 8.5
Central nervous system SF126 10.2
Central nervous system SF295 10.8
Central nervous system SNB19 9.9
Central nervous system SNU1105 10.4
Central nervous system SNU201 10.5
Central nervous system SNU466 10.4
Central nervous system SNU489 9.8
Central nervous system SNU626 10.2
Central nervous system SNU738 9.6
Central nervous system SW1088 10.2
Central nervous system SW1783 9.9
Central nervous system T98G 10.6
Central nervous system TM31 9.8
Central nervous system U118MG 10
Central nervous system U138MG 11
Central nervous system U251MG 10.2
Central nervous system U87MG 10.9
Central nervous system YH13 10.4
Central nervous system YKG1 10.3
Endometrium AN3CA 5.5
Endometrium COLO684 9.7
Endometrium EFE184 8.9
Endometrium EN 9.5
Endometrium ESS1 10.2
Endometrium HEC108 9.9
Endometrium HEC151 9.7
Endometrium HEC1A 10
Endometrium HEC1B 8.6
Endometrium HEC251 9.6
Endometrium HEC265 10.3
Endometrium HEC50B 10.4
Endometrium HEC59 6.5
Endometrium HEC6 10.4
Endometrium ISHIKAWAHERAKLIO02ER 9.4
Endometrium JHUEM1 9.1
Endometrium JHUEM2 10.3
Endometrium JHUEM3 10.5
Endometrium KLE 9.2
Endometrium MFE280 10
Endometrium MFE296 8.4
Endometrium MFE319 9.6
Endometrium RL952 10.4
Endometrium SNGM 10.4
Endometrium SNU1077 9.5
Endometrium SNU685 9.7
Endometrium TEN 9
Haematopoietic and lymphoid 697 10.6
Haematopoietic and lymphoid A3KAW 10.5
Haematopoietic and lymphoid A4FUK 10.6
Haematopoietic and lymphoid ALLSIL 10.2
Haematopoietic and lymphoid AML193 6.6
Haematopoietic and lymphoid AMO1 10.6
Haematopoietic and lymphoid BCP1 9.7
Haematopoietic and lymphoid BDCM 7.2
Haematopoietic and lymphoid BL41 10.3
Haematopoietic and lymphoid BL70 10.2
Haematopoietic and lymphoid BV173 10.3
Haematopoietic and lymphoid CA46 10.6
Haematopoietic and lymphoid CI1 10.1
Haematopoietic and lymphoid CMK115 9.2
Haematopoietic and lymphoid CMK86 6.3
Haematopoietic and lymphoid CMK 9
Haematopoietic and lymphoid CMLT1 10.2
Haematopoietic and lymphoid COLO775 10.5
Haematopoietic and lymphoid DAUDI 10.4
Haematopoietic and lymphoid DB 10.8
Haematopoietic and lymphoid DEL 10.1
Haematopoietic and lymphoid DND41 9.1
Haematopoietic and lymphoid DOHH2 10.5
Haematopoietic and lymphoid EB1 10
Haematopoietic and lymphoid EB2 9.7
Haematopoietic and lymphoid EHEB 4.8
Haematopoietic and lymphoid EJM 10.1
Haematopoietic and lymphoid EM2 9.5
Haematopoietic and lymphoid EOL1 10.9
Haematopoietic and lymphoid F36P 9
Haematopoietic and lymphoid GA10 10
Haematopoietic and lymphoid GDM1 8.1
Haematopoietic and lymphoid GRANTA519 9.1
Haematopoietic and lymphoid HDLM2 10.1
Haematopoietic and lymphoid HDMYZ 9.9
Haematopoietic and lymphoid HEL9217 9.4
Haematopoietic and lymphoid HEL 8.9
Haematopoietic and lymphoid HH 7.1
Haematopoietic and lymphoid HL60 9.1
Haematopoietic and lymphoid HPBALL 9.8
Haematopoietic and lymphoid HS604T 10.8
Haematopoietic and lymphoid HS611T 8.9
Haematopoietic and lymphoid HS616T 11.2
Haematopoietic and lymphoid HS751T 10.9
Haematopoietic and lymphoid HT 10.2
Haematopoietic and lymphoid HTK 10
Haematopoietic and lymphoid HUNS1 5.8
Haematopoietic and lymphoid HUT102 8.6
Haematopoietic and lymphoid HUT78 9.2
Haematopoietic and lymphoid JEKO1 10.2
Haematopoietic and lymphoid JK1 7.2
Haematopoietic and lymphoid JM1 8.8
Haematopoietic and lymphoid JURKAT 10.3
Haematopoietic and lymphoid JURLMK1 11.7
Haematopoietic and lymphoid JVM2 5.6
Haematopoietic and lymphoid JVM3 5.7
Haematopoietic and lymphoid K562 7.2
Haematopoietic and lymphoid KARPAS299 10.7
Haematopoietic and lymphoid KARPAS422 10.8
Haematopoietic and lymphoid KARPAS620 9.5
Haematopoietic and lymphoid KASUMI1 10.3
Haematopoietic and lymphoid KASUMI2 10.1
Haematopoietic and lymphoid KASUMI6 9.7
Haematopoietic and lymphoid KCL22 10.4
Haematopoietic and lymphoid KE37 10.7
Haematopoietic and lymphoid KE97 5.1
Haematopoietic and lymphoid KG1 9.3
Haematopoietic and lymphoid KHM1B 10.5
Haematopoietic and lymphoid KIJK 10.5
Haematopoietic and lymphoid KMH2 10.4
Haematopoietic and lymphoid KMM1 10
Haematopoietic and lymphoid KMS11 10.6
Haematopoietic and lymphoid KMS12BM 10.1
Haematopoietic and lymphoid KMS18 8.4
Haematopoietic and lymphoid KMS20 10.6
Haematopoietic and lymphoid KMS21BM 11.3
Haematopoietic and lymphoid KMS26 11.1
Haematopoietic and lymphoid KMS27 11.1
Haematopoietic and lymphoid KMS28BM 11.1
Haematopoietic and lymphoid KMS34 10.5
Haematopoietic and lymphoid KO52 8.5
Haematopoietic and lymphoid KOPN8 9.4
Haematopoietic and lymphoid KU812 8.9
Haematopoietic and lymphoid KYO1 8.8
Haematopoietic and lymphoid L1236 8.7
Haematopoietic and lymphoid L363 9.8
Haematopoietic and lymphoid L428 8.8
Haematopoietic and lymphoid L540 10
Haematopoietic and lymphoid LAMA84 10.2
Haematopoietic and lymphoid LOUCY 9.7
Haematopoietic and lymphoid LP1 11.2
Haematopoietic and lymphoid M07E 4.9
Haematopoietic and lymphoid MC116 9.6
Haematopoietic and lymphoid ME1 9.3
Haematopoietic and lymphoid MEC1 8.6
Haematopoietic and lymphoid MEC2 6.8
Haematopoietic and lymphoid MEG01 8.9
Haematopoietic and lymphoid MHHCALL2 10.4
Haematopoietic and lymphoid MHHCALL3 10.2
Haematopoietic and lymphoid MHHCALL4 9.8
Haematopoietic and lymphoid MINO 9.5
Haematopoietic and lymphoid MJ 9.4
Haematopoietic and lymphoid MM1S 10.5
Haematopoietic and lymphoid MOLM13 10.2
Haematopoietic and lymphoid MOLM16 9.1
Haematopoietic and lymphoid MOLM6 9.8
Haematopoietic and lymphoid MOLP2 11.1
Haematopoietic and lymphoid MOLP8 11.2
Haematopoietic and lymphoid MOLT13 8.4
Haematopoietic and lymphoid MOLT16 10.4
Haematopoietic and lymphoid MOLT4 8.7
Haematopoietic and lymphoid MONOMAC1 9.9
Haematopoietic and lymphoid MONOMAC6 9.7
Haematopoietic and lymphoid MOTN1 9.5
Haematopoietic and lymphoid MUTZ5 9.5
Haematopoietic and lymphoid MV411 9.7
Haematopoietic and lymphoid NALM19 10.4
Haematopoietic and lymphoid NALM1 10.4
Haematopoietic and lymphoid NALM6 10.6
Haematopoietic and lymphoid NAMALWA 9.2
Haematopoietic and lymphoid NB4 9
Haematopoietic and lymphoid NCIH929 9.7
Haematopoietic and lymphoid NCO2 9.3
Haematopoietic and lymphoid NOMO1 9.7
Haematopoietic and lymphoid NUDHL1 10.2
Haematopoietic and lymphoid NUDUL1 10.3
Haematopoietic and lymphoid OCIAML2 9.9
Haematopoietic and lymphoid OCIAML3 9.7
Haematopoietic and lymphoid OCIAML5 10
Haematopoietic and lymphoid OCILY10 10.2
Haematopoietic and lymphoid OCILY19 10.3
Haematopoietic and lymphoid OCILY3 10.1
Haematopoietic and lymphoid OCIM1 10.8
Haematopoietic and lymphoid OPM2 10.7
Haematopoietic and lymphoid P12ICHIKAWA 9.9
Haematopoietic and lymphoid P31FUJ 9.5
Haematopoietic and lymphoid P3HR1 10.6
Haematopoietic and lymphoid PCM6 10.5
Haematopoietic and lymphoid PEER 9
Haematopoietic and lymphoid PF382 9.4
Haematopoietic and lymphoid PFEIFFER 9.9
Haematopoietic and lymphoid PL21 10.6
Haematopoietic and lymphoid RAJI 10.8
Haematopoietic and lymphoid RCHACV 10.1
Haematopoietic and lymphoid REC1 8.3
Haematopoietic and lymphoid REH 9.8
Haematopoietic and lymphoid RI1 9.3
Haematopoietic and lymphoid RL 10.5
Haematopoietic and lymphoid RPMI8226 10.2
Haematopoietic and lymphoid RPMI8402 8.6
Haematopoietic and lymphoid RS411 9.9
Haematopoietic and lymphoid SEM 10.1
Haematopoietic and lymphoid SET2 9.9
Haematopoietic and lymphoid SIGM5 9.3
Haematopoietic and lymphoid SKM1 9.7
Haematopoietic and lymphoid SKMM2 11.3
Haematopoietic and lymphoid SR786 10.9
Haematopoietic and lymphoid ST486 9.2
Haematopoietic and lymphoid SUDHL10 10.7
Haematopoietic and lymphoid SUDHL1 9.8
Haematopoietic and lymphoid SUDHL4 10.5
Haematopoietic and lymphoid SUDHL5 10.6
Haematopoietic and lymphoid SUDHL6 9.3
Haematopoietic and lymphoid SUDHL8 10.6
Haematopoietic and lymphoid SUPB15 9.9
Haematopoietic and lymphoid SUPHD1 8.8
Haematopoietic and lymphoid SUPM2 10.1
Haematopoietic and lymphoid SUPT11 8.2
Haematopoietic and lymphoid SUPT1 8.1
Haematopoietic and lymphoid TALL1 9.3
Haematopoietic and lymphoid TF1 9.2
Haematopoietic and lymphoid THP1 9.3
Haematopoietic and lymphoid TO175T 10.9
Haematopoietic and lymphoid TOLEDO 9.4
Haematopoietic and lymphoid U266B1 10.5
Haematopoietic and lymphoid U937 9.6
Haematopoietic and lymphoid UT7 9.6
Haematopoietic and lymphoid WSUDLCL2 10.7
Kidney 769P 10.2
Kidney 786O 10.9
Kidney A498 10.6
Kidney A704 9.6
Kidney ACHN 9.9
Kidney BFTC909 9.7
Kidney CAKI1 10.7
Kidney CAKI2 9.4
Kidney CAL54 9.7
Kidney KMRC1 10.8
Kidney KMRC20 10.2
Kidney KMRC2 10.2
Kidney KMRC3 9.9
Kidney OSRC2 10.3
Kidney RCC10RGB 9.5
Kidney SNU1272 10.4
Kidney SNU349 9.1
Kidney TUHR10TKB 10.3
Kidney TUHR14TKB 10.7
Kidney TUHR4TKB 10
Kidney VMRCRCW 9.9
Kidney VMRCRCZ 9.9
Large intestine C2BBE1 10
Large intestine CCK81 9
Large intestine CL11 10.2
Large intestine CL14 9.4
Large intestine CL34 10.5
Large intestine CL40 10.4
Large intestine COLO205 10
Large intestine COLO320 9.6
Large intestine COLO678 8.8
Large intestine CW2 10.2
Large intestine DLD1 10.4
Large intestine GP2D 10.5
Large intestine HCC56 9.4
Large intestine HCT116 10.6
Large intestine HCT15 10.5
Large intestine HS675T 10.2
Large intestine HS698T 11.5
Large intestine HT115 10.5
Large intestine HT29 10.3
Large intestine HT55 9.6
Large intestine KM12 10.7
Large intestine LOVO 9.9
Large intestine LS1034 9.1
Large intestine LS123 9.7
Large intestine LS180 10.7
Large intestine LS411N 10.5
Large intestine LS513 10.1
Large intestine MDST8 10.2
Large intestine NCIH508 9.7
Large intestine NCIH716 10.7
Large intestine NCIH747 9.7
Large intestine OUMS23 9.9
Large intestine RCM1 9.7
Large intestine RKO 10.3
Large intestine SKCO1 10.3
Large intestine SNU1040 10.9
Large intestine SNU1197 10.2
Large intestine SNU175 9.8
Large intestine SNU283 10
Large intestine SNU407 9.9
Large intestine SNU503 10.2
Large intestine SNU61 10.2
Large intestine SNU81 10.6
Large intestine SNUC1 10
Large intestine SNUC2A 10.8
Large intestine SNUC4 10.5
Large intestine SNUC5 10.1
Large intestine SW1116 9.6
Large intestine SW1417 8.8
Large intestine SW1463 9.9
Large intestine SW403 9.8
Large intestine SW480 9.8
Large intestine SW48 10.7
Large intestine SW620 7.3
Large intestine SW837 10.2
Large intestine SW948 9.7
Large intestine T84 9.3
Liver ALEXANDERCELLS 10.4
Liver C3A 5
Liver HEP3B217 9.9
Liver HEPG2 5.1
Liver HLE 9.3
Liver HLF 10.1
Liver HUH1 10
Liver HUH6 8.8
Liver HUH7 10.9
Liver JHH1 8.1
Liver JHH2 9.9
Liver JHH4 9.7
Liver JHH5 9.4
Liver JHH6 10.6
Liver JHH7 9.2
Liver LI7 10.6
Liver PLCPRF5 10.1
Liver SKHEP1 9.3
Liver SNU182 10.2
Liver SNU387 10
Liver SNU398 9.2
Liver SNU423 9.5
Liver SNU449 10
Liver SNU475 10.2
Liver SNU761 11.4
Liver SNU878 10.9
Liver SNU886 10.4
Lung A549 10.6
Lung ABC1 10.1
Lung BEN 9.6
Lung CAL12T 9.7
Lung CALU1 9.6
Lung CALU3 9.1
Lung CALU6 9.2
Lung CHAGOK1 10.8
Lung COLO668 10.6
Lung COLO699 9.4
Lung CORL105 11.2
Lung CORL23 10.5
Lung CORL24 7.1
Lung CORL279 8.9
Lung CORL311 4.8
Lung CORL47 10.5
Lung CORL51 9.4
Lung CORL88 9.3
Lung CORL95 10.1
Lung CPCN 6.8
Lung DMS114 6.7
Lung DMS153 9.6
Lung DMS273 10.4
Lung DMS454 9.3
Lung DMS53 9.9
Lung DMS79 9.9
Lung DV90 10.9
Lung EBC1 9.9
Lung EPLC272H 9
Lung HARA 9.8
Lung HCC1171 10.7
Lung HCC1195 10
Lung HCC15 10
Lung HCC2279 11.3
Lung HCC2935 10
Lung HCC33 8.6
Lung HCC366 10.3
Lung HCC4006 11.3
Lung HCC44 10.7
Lung HCC78 10.8
Lung HCC827 10.4
Lung HCC95 9.2
Lung HLC1 10.2
Lung HLFA 10.6
Lung HS229T 10.5
Lung HS618T 10.7
Lung IALM 10.3
Lung KNS62 10.3
Lung LC1F 10
Lung LC1SQSF 9.7
Lung LCLC103H 10.5
Lung LCLC97TM1 11.2
Lung LK2 9.7
Lung LOUNH91 8.8
Lung LU65 10.2
Lung LU99 10.5
Lung LUDLU1 9.9
Lung LXF289 10.7
Lung MORCPR 10.8
Lung NCIH1048 9.5
Lung NCIH1092 8.5
Lung NCIH1105 9.1
Lung NCIH1155 10.2
Lung NCIH1184 8.2
Lung NCIH1299 8.8
Lung NCIH1339 10.9
Lung NCIH1341 10.3
Lung NCIH1355 11.1
Lung NCIH1373 10.5
Lung NCIH1385 10.6
Lung NCIH1395 10
Lung NCIH1435 9.9
Lung NCIH1436 10.7
Lung NCIH1437 10.8
Lung NCIH146 9.4
Lung NCIH1563 10.5
Lung NCIH1568 10.7
Lung NCIH1573 10.6
Lung NCIH1581 5.9
Lung NCIH1618 9.9
Lung NCIH1623 9.9
Lung NCIH1648 9.6
Lung NCIH1650 9.7
Lung NCIH1651 10.3
Lung NCIH1666 9.9
Lung NCIH1693 9.5
Lung NCIH1694 9.7
Lung NCIH1703 9.4
Lung NCIH1734 9.8
Lung NCIH1755 10.4
Lung NCIH1781 9.4
Lung NCIH1792 10.6
Lung NCIH1793 10.9
Lung NCIH1836 9.3
Lung NCIH1838 11.6
Lung NCIH1869 10.7
Lung NCIH1876 9.7
Lung NCIH1915 10.6
Lung NCIH1930 8.4
Lung NCIH1944 10.6
Lung NCIH1963 9.6
Lung NCIH196 9.8
Lung NCIH1975 9.8
Lung NCIH2009 9.7
Lung NCIH2023 10
Lung NCIH2029 9.7
Lung NCIH2030 9.1
Lung NCIH2066 8.7
Lung NCIH2081 9.3
Lung NCIH2085 9.4
Lung NCIH2087 9.9
Lung NCIH209 9.2
Lung NCIH2106 8
Lung NCIH2110 10.9
Lung NCIH211 9
Lung NCIH2122 10.6
Lung NCIH2126 11.4
Lung NCIH2141 9.6
Lung NCIH2170 10.9
Lung NCIH2171 10
Lung NCIH2172 11.1
Lung NCIH2196 9.9
Lung NCIH2227 10
Lung NCIH2228 10.6
Lung NCIH226 9.3
Lung NCIH2286 10.6
Lung NCIH2291 10.7
Lung NCIH2342 8.7
Lung NCIH2347 10.3
Lung NCIH23 8.7
Lung NCIH2405 10.2
Lung NCIH2444 9.4
Lung NCIH292 10.3
Lung NCIH322 10.4
Lung NCIH3255 9.8
Lung NCIH358 10
Lung NCIH441 10.6
Lung NCIH446 10.5
Lung NCIH460 10.5
Lung NCIH510 8.9
Lung NCIH520 8.8
Lung NCIH522 8.1
Lung NCIH524 9.9
Lung NCIH526 8.2
Lung NCIH596 10.5
Lung NCIH647 10.5
Lung NCIH650 10.4
Lung NCIH661 9
Lung NCIH69 9.4
Lung NCIH727 8.9
Lung NCIH810 7.7
Lung NCIH82 9.6
Lung NCIH838 10.4
Lung NCIH841 6.5
Lung NCIH854 10
Lung NCIH889 9.3
Lung PC14 10
Lung RERFLCAD1 10
Lung RERFLCAD2 9.9
Lung RERFLCAI 10
Lung RERFLCKJ 10.5
Lung RERFLCMS 10.2
Lung RERFLCSQ1 10.2
Lung SBC5 8.5
Lung SCLC21H 11.4
Lung SHP77 9.2
Lung SKLU1 10.3
Lung SKMES1 10
Lung SQ1 10.3
Lung SW1271 10
Lung SW1573 10
Lung SW900 10
Lung VMRCLCD 9.2
Lung VMRCLCP 9.9
Oesophagus COLO680N 9.4
Oesophagus ECGI10 10
Oesophagus KYSE140 8.9
Oesophagus KYSE150 9.5
Oesophagus KYSE180 9.1
Oesophagus KYSE270 9.5
Oesophagus KYSE30 8.3
Oesophagus KYSE410 9.3
Oesophagus KYSE450 9.9
Oesophagus KYSE510 9.8
Oesophagus KYSE520 9.3
Oesophagus KYSE70 9.8
Oesophagus OE19 10
Oesophagus OE33 10.5
Oesophagus TE10 9.3
Oesophagus TE11 9.6
Oesophagus TE14 10.2
Oesophagus TE15 9
Oesophagus TE1 9.3
Oesophagus TE4 11.6
Oesophagus TE5 9.2
Oesophagus TE6 9.6
Oesophagus TE8 9.8
Oesophagus TE9 10.5
Oesophagus TT 9.6
Ovary 59M 9.8
Ovary A2780 10
Ovary CAOV3 9.4
Ovary CAOV4 8.5
Ovary COLO704 9.9
Ovary COV318 8.2
Ovary COV362 10.1
Ovary COV434 9.1
Ovary COV504 9.7
Ovary COV644 10.7
Ovary EFO21 9.4
Ovary EFO27 9
Ovary ES2 9.7
Ovary FUOV1 6.9
Ovary HEYA8 10.2
Ovary HS571T 11.2
Ovary IGROV1 8.7
Ovary JHOC5 9.3
Ovary JHOM1 9.8
Ovary JHOM2B 10.6
Ovary JHOS2 9.2
Ovary JHOS4 9.4
Ovary KURAMOCHI 9
Ovary MCAS 10
Ovary NIHOVCAR3 9.5
Ovary OAW28 8.3
Ovary OAW42 6
Ovary OC314 9.3
Ovary OC316 9.3
Ovary ONCODG1 9.8
Ovary OV56 10
Ovary OV7 10
Ovary OV90 9.4
Ovary OVCAR4 9.4
Ovary OVCAR8 10.3
Ovary OVISE 8.6
Ovary OVK18 9.9
Ovary OVKATE 9.9
Ovary OVMANA 8.8
Ovary OVSAHO 5.3
Ovary OVTOKO 9.3
Ovary RMGI 9.3
Ovary RMUGS 10.4
Ovary SKOV3 9
Ovary SNU119 9.4
Ovary SNU840 9.4
Ovary SNU8 9.4
Ovary TOV112D 8.1
Ovary TOV21G 9.3
Ovary TYKNU 9.9
Pancreas ASPC1 9.3
Pancreas BXPC3 10
Pancreas CAPAN1 9.9
Pancreas CAPAN2 10.4
Pancreas CFPAC1 10
Pancreas DANG 9.2
Pancreas HPAC 10.4
Pancreas HPAFII 10.1
Pancreas HS766T 10.2
Pancreas HUPT3 10.3
Pancreas HUPT4 9.5
Pancreas KCIMOH1 9.8
Pancreas KLM1 9.9
Pancreas KP2 9.6
Pancreas KP3 10.1
Pancreas KP4 9.1
Pancreas L33 9.9
Pancreas MIAPACA2 9.4
Pancreas PANC0203 10.1
Pancreas PANC0213 10.3
Pancreas PANC0327 9.3
Pancreas PANC0403 10.5
Pancreas PANC0504 10.5
Pancreas PANC0813 9.8
Pancreas PANC1005 10
Pancreas PANC1 9.5
Pancreas PATU8902 8.9
Pancreas PATU8988S 9.2
Pancreas PATU8988T 9.9
Pancreas PK1 9.9
Pancreas PK45H 10
Pancreas PK59 9.4
Pancreas PL45 9.9
Pancreas PSN1 9.9
Pancreas QGP1 10.4
Pancreas SNU213 10.5
Pancreas SNU324 11.5
Pancreas SNU410 9.4
Pancreas SU8686 10.9
Pancreas SUIT2 10.5
Pancreas SW1990 9.7
Pancreas T3M4 10.6
Pancreas TCCPAN2 9
Pancreas YAPC 10.2
Pleura ACCMESO1 9.7
Pleura DM3 11.1
Pleura ISTMES1 9.9
Pleura ISTMES2 9.1
Pleura JL1 10.1
Pleura MPP89 9.9
Pleura MSTO211H 10.5
Pleura NCIH2052 10.4
Pleura NCIH2452 9.8
Pleura NCIH28 8.8
Prostate 22RV1 10.3
Prostate DU145 9.7
Prostate LNCAPCLONEFGC 11.6
Prostate MDAPCA2B 11.2
Prostate NCIH660 9.4
Prostate PC3 9.3
Prostate VCAP 11
Salivary gland A253 9.5
Salivary gland YD15 9.5
Skin A101D 9.9
Skin A2058 10.2
Skin A375 9.4
Skin C32 10.2
Skin CHL1 9.4
Skin CJM 10.7
Skin COLO679 9.8
Skin COLO741 10.1
Skin COLO783 10.5
Skin COLO792 10.9
Skin COLO800 10.1
Skin COLO818 10.3
Skin COLO829 10.6
Skin COLO849 9.8
Skin G361 9.7
Skin GRM 9.6
Skin HMCB 9.1
Skin HS294T 10.3
Skin HS600T 11.1
Skin HS688AT 11
Skin HS695T 9.5
Skin HS839T 10.4
Skin HS852T 10.7
Skin HS895T 11.1
Skin HS934T 11
Skin HS936T 8.6
Skin HS939T 10.2
Skin HS940T 11.1
Skin HS944T 9.5
Skin HT144 10
Skin IGR1 10.2
Skin IGR37 8.8
Skin IGR39 9.4
Skin IPC298 10
Skin K029AX 8.6
Skin LOXIMVI 9.8
Skin MALME3M 9
Skin MDAMB435S 10.2
Skin MELHO 8.8
Skin MELJUSO 9
Skin MEWO 10.2
Skin RPMI7951 10.3
Skin RVH421 10
Skin SH4 10
Skin SKMEL1 9.3
Skin SKMEL24 10.4
Skin SKMEL28 9.4
Skin SKMEL2 5.6
Skin SKMEL30 9.3
Skin SKMEL31 10.5
Skin SKMEL3 10.3
Skin SKMEL5 8.8
Skin UACC257 8.5
Skin UACC62 9.5
Skin WM115 10.1
Skin WM1799 9.9
Skin WM2664 9.5
Skin WM793 11
Skin WM88 10.4
Skin WM983B 10.2
Small intestine HUTU80 8.6
Soft tissue A204 8.9
Soft tissue G401 8.8
Soft tissue G402 9.9
Soft tissue GCT 10.4
Soft tissue HS729 9.6
Soft tissue HT1080 10.6
Soft tissue KYM1 9.9
Soft tissue MESSA 10.8
Soft tissue RD 10.6
Soft tissue RH30 10
Soft tissue RH41 10.5
Soft tissue RKN 8.8
Soft tissue S117 9.7
Soft tissue SJRH30 8.5
Soft tissue SKLMS1 10.4
Soft tissue SKUT1 10.2
Soft tissue TE125T 11.7
Soft tissue TE159T 11.2
Soft tissue TE441T 9.3
Soft tissue TE617T 6.9
Stomach 2313287 10.7
Stomach AGS 9.7
Stomach AZ521 9.5
Stomach ECC10 9.2
Stomach ECC12 9.2
Stomach FU97 8.8
Stomach GCIY 9.4
Stomach GSS 8.9
Stomach GSU 9.9
Stomach HGC27 9.7
Stomach HS746T 10.9
Stomach HUG1N 10.2
Stomach IM95 10.7
Stomach KATOIII 10.3
Stomach KE39 10
Stomach LMSU 11.3
Stomach MKN1 10
Stomach MKN45 10.7
Stomach MKN74 9.9
Stomach MKN7 9.7
Stomach NCCSTCK140 9.9
Stomach NCIN87 10.7
Stomach NUGC2 8.8
Stomach NUGC3 9.2
Stomach NUGC4 10.1
Stomach OCUM1 9.9
Stomach RERFGC1B 8.9
Stomach SH10TC 9.5
Stomach SNU16 10.1
Stomach SNU1 10.8
Stomach SNU216 9.6
Stomach SNU520 9.8
Stomach SNU5 11.8
Stomach SNU601 10.6
Stomach SNU620 10.6
Stomach SNU668 10.5
Stomach SNU719 9.2
Stomach TGBC11TKB 10.7
Thyroid 8305C 10.5
Thyroid 8505C 10
Thyroid BCPAP 10.1
Thyroid BHT101 10.2
Thyroid CAL62 9.7
Thyroid CGTHW1 10.1
Thyroid FTC133 10
Thyroid FTC238 10.3
Thyroid ML1 10.1
Thyroid SW579 9.8
Thyroid TT2609C02 10
Thyroid TT 10.9
Upper aerodigestive tract BHY 8.8
Upper aerodigestive tract BICR16 9.7
Upper aerodigestive tract BICR18 10
Upper aerodigestive tract BICR22 10.3
Upper aerodigestive tract BICR31 9.8
Upper aerodigestive tract BICR56 11.1
Upper aerodigestive tract BICR6 9.9
Upper aerodigestive tract CAL27 9.2
Upper aerodigestive tract CAL33 9.6
Upper aerodigestive tract DETROIT562 9.7
Upper aerodigestive tract FADU 9.8
Upper aerodigestive tract HS840T 10.6
Upper aerodigestive tract HSC2 9.9
Upper aerodigestive tract HSC3 10.3
Upper aerodigestive tract HSC4 9.1
Upper aerodigestive tract PECAPJ15 9.4
Upper aerodigestive tract PECAPJ34CLONEC12 9.6
Upper aerodigestive tract PECAPJ41CLONED2 10.1
Upper aerodigestive tract PECAPJ49 10.1
Upper aerodigestive tract SCC15 9.7
Upper aerodigestive tract SCC25 10
Upper aerodigestive tract SCC4 9.7
Upper aerodigestive tract SCC9 10.5
Upper aerodigestive tract SNU1076 8.6
Upper aerodigestive tract SNU1214 10.1
Upper aerodigestive tract SNU46 9.8
Upper aerodigestive tract SNU899 9.9
Upper aerodigestive tract YD10B 8.4
Upper aerodigestive tract YD38 9.7
Upper aerodigestive tract YD8 10.4
Urinary tract 5637 9.6
Urinary tract 639V 10.7
Urinary tract 647V 10.4
Urinary tract BC3C 10.4
Urinary tract BFTC905 8.6
Urinary tract CAL29 9.3
Urinary tract HS172T 10.2
Urinary tract HT1197 9.9
Urinary tract HT1376 9.3
Urinary tract J82 9.7
Urinary tract JMSU1 10.3
Urinary tract KMBC2 9.7
Urinary tract KU1919 9
Urinary tract RT11284 9.7
Urinary tract RT112 8.9
Urinary tract RT4 9.5
Urinary tract SCABER 8.8
Urinary tract SW1710 9.8
Urinary tract SW780 9.9
Urinary tract T24 9.6
Urinary tract TCCSUP 9.7
Urinary tract UMUC1 9.4
Urinary tract UMUC3 10
Urinary tract VMCUB1 10.1
> The Human Protein Atlas (HPA)
 


Tissue Expression Level (TPM)
Adipose tissue 45.4
Adrenal gland 22.7
Appendix 20
Bone marrow 5.9
Breast 31.5
Cerebral cortex 31.7
Cervix, uterine 58.2
Colon 14
Duodenum 6.9
Endometrium 50.7
Epididymis 14.2
Esophagus 29.4
Fallopian tube 28.7
Gallbladder 39
Heart muscle 25.6
Kidney 10
Liver 23.9
Lung 26.6
Lymph node 12.6
Ovary 22.6
Pancreas 4.3
Parathyroid gland 59.7
Placenta 25.4
Prostate 50.9
Rectum 16.1
Salivary gland 5.5
Seminal vesicle 26.2
Skeletal muscle 33.2
Skin 25.1
Small intestine 9.1
Smooth muscle 47
Spleen 21.8
Stomach 11.7
Testis 25.9
Thyroid gland 21.8
Tonsil 14.2
Urinary bladder 23.7
> Text Mining based Expression
 
PMID Expression Cancer Evidence
27132511underexpressionBreast CarcinomaSET9 expression levels were significantly higher in samples from patients with pathological complete remission than in samples from patients with disease recurrence, which indicates that SET9 acts as a tumor suppressor in breast cancer and that its expression may serve as a prognostic marker for malignancy.
26701885loss of expression; underexpressionGastric CarcinomaAmong the 376 primary GCs, 129 cases (34.3%) showed loss or weak expression of SET7/9 protein compared to matched non-cancerous tissues by immunohistochemistry.
20959290overexpressionProstate CarcinomaWe also show that SET9 is pro-proliferative and anti-apoptotic in prostate cancer cells and demonstrates up-regulated nuclear expression in prostate cancer tissue.
17998933overexpressionColorectal Carcinoma; Breast Carcinoma; Liver and Intrahepatic Bile Duct CarcinomaWe earlier showed that SMYD3, a histone H3-lysine 4-specific methyltransferase, is frequently upregulated in human colorectal, liver and breast cancer compared to their matched non-cancerous cells, and that its activity is associated with the growth of these tumors.
27132511UnderexpressionBreast CarcinomaSET9 expression levels were significantly higher in samples from patients with pathological complete remission than in samples from patients with disease recurrence, which indicates that SET9 acts as a tumor suppressor in breast cancer and that its expression may serve as a prognostic marker for malignancy.
Summary
SymbolSETD7
NameSET domain containing lysine methyltransferase 7
Aliases KIAA1717; SET7/9; Set9; KMT7; H3-K4-HMTase SETD7; SET domain-containing protein 7; histone H3-K4 methyltrans ......
Location4q31.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Somatic copy number alteration in primary tomur tissue
> The Cancer Genome Atlas (TCGA)
 


  Correlation between expression and SCNA as well as percentage of patients in different status.
Cancer Full Name # Sample R P % Loss % Neutral % Gain Status
BLCABladder urothelial carcinoma4040.2522.8e-0739.152.28.7Loss
BRCABreast invasive carcinoma10750.3333.14e-2929.5619.5Neutral
CESCCervical and endocervical cancers2920.2839.11e-0734.957.97.2Loss
COADColon adenocarcinoma4490.4072.25e-1930.565.93.6Neutral
ESCAEsophageal carcinoma1830.4472.36e-1045.939.914.2Loss
GBMGlioblastoma multiforme1470.2680.0010215.678.95.4Neutral
HNSCHead and Neck squamous cell carcinoma5140.3022.64e-1231.558.89.7Neutral
KIRCKidney renal clear cell carcinoma5250.231.04e-0714.3832.7Neutral
KIRPKidney renal papillary cell carcinoma2880.1790.002299.487.23.5Neutral
LAMLAcute Myeloid Leukemia1660.1810.01951.297.61.2Neutral
LGGBrain Lower Grade Glioma5130.3191.23e-1323.675.80.6Neutral
LIHCLiver hepatocellular carcinoma3640.4353.09e-1841.254.44.4Loss
LUADLung adenocarcinoma5120.3493.8e-1631.458.410.2Neutral
LUSCLung squamous cell carcinoma4980.4486.69e-2663.131.75.2Loss
OVOvarian serous cystadenocarcinoma3000.3295.5e-0964.326.39.3Loss
PAADPancreatic adenocarcinoma1770.1880.012115.879.15.1Neutral
PCPGPheochromocytoma and Paraganglioma1620.2720.0004656.890.13.1Neutral
PRADProstate adenocarcinoma4910.2681.61e-095.591.23.3Neutral
READRectum adenocarcinoma1640.3232.53e-0540.953.75.5Loss
SARCSarcoma2550.3211.56e-0724.357.618Neutral
SKCMSkin Cutaneous Melanoma3670.2261.25e-0524.860.514.7Neutral
STADStomach adenocarcinoma4130.3174.43e-1137.555.27.3Loss
TGCTTesticular Germ Cell Tumors1500.3235.42e-0572.727.30Loss
THCAThyroid carcinoma4970.0830.06320.498.61Neutral
THYMThymoma1190.0680.4633.4951.7Neutral
UCECUterine Corpus Endometrial Carcinoma5370.1610.00018519.4782.6Neutral
Summary
SymbolSETD7
NameSET domain containing lysine methyltransferase 7
Aliases KIAA1717; SET7/9; Set9; KMT7; H3-K4-HMTase SETD7; SET domain-containing protein 7; histone H3-K4 methyltrans ......
Location4q31.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Methylation level in the promoter region of CR
> Methylation level in the promoter region of CR
 


  Correlation between expression and methylation as well as differential methylation analysis.
Cancer Full Name R P # N # T Delta beta (T vs N) P value (T vs N) Status
BLCABladder urothelial carcinoma-0.0780.109174080.0010.834NS/NA
BRCABreast invasive carcinoma-0.2051.26e-098378500.00751NS/NA
CESCCervical and endocervical cancers-0.2228.81e-053306NANANS/NA
COADColon adenocarcinoma-0.0840.138192970.0015.07e-06NS/NA
ESCAEsophageal carcinoma-0.2650.0002029185NANANS/NA
GBMGlioblastoma multiforme-0.4040.000936164NANANS/NA
HNSCHead and Neck squamous cell carcinoma-0.2091.02e-06205220.0028.57e-05NS/NA
KIRCKidney renal clear cell carcinoma0.0590.272243190.0027.78e-10NS/NA
KIRPKidney renal papillary cell carcinoma-0.1470.011232750.0020.593NS/NA
LAMLAcute Myeloid Leukemia-0.361.69e-060170NANANS/NA
LGGBrain Lower Grade Glioma-0.1090.01220530NANANS/NA
LIHCLiver hepatocellular carcinoma-0.2571.32e-0741373-0.0540.000323NS/NA
LUADLung adenocarcinoma-0.1390.0023621456-0.0479.33e-06NS/NA
LUSCLung squamous cell carcinoma-0.2354.24e-068370NANANS/NA
OVOvarian serous cystadenocarcinoma-0.650.066609NANANS/NA
PAADPancreatic adenocarcinoma-0.1040.1594179NANANS/NA
PCPGPheochromocytoma and Paraganglioma-0.1660.02293184NANANS/NA
PRADProstate adenocarcinoma-0.1480.000612354980.0010.0017NS/NA
READRectum adenocarcinoma-0.2170.0298299NANANS/NA
SARCSarcoma-0.2380.0001040263NANANS/NA
SKCMSkin Cutaneous Melanoma-0.1370.002981471NANANS/NA
STADStomach adenocarcinoma-0.2442.15e-060372NANANS/NA
TGCTTesticular Germ Cell Tumors-0.2620.0009810156NANANS/NA
THCAThyroid carcinoma-0.0690.10250509-0.0020.598NS/NA
THYMThymoma-0.3693.36e-052120NANANS/NA
UCECUterine Corpus Endometrial Carcinoma-0.0920.047234431-0.0020.442NS/NA
Summary
SymbolSETD7
NameSET domain containing lysine methyltransferase 7
Aliases KIAA1717; SET7/9; Set9; KMT7; H3-K4-HMTase SETD7; SET domain-containing protein 7; histone H3-K4 methyltrans ......
Location4q31.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Primary tumor tissue from TCGA
> Normal tumor tissue from HPA
>The Cancer Genome Atlas (TCGA)
 
There is no record.
> The Human Protein Atlas (HPA)
 


Tissue Level Level Name
Adrenal gland 1 Low
Appendix 2 Medium
Bone marrow 2 Medium
Breast 1 Low
Bronchus 2 Medium
Caudate 1 Low
Cerebellum 1 Low
Cerebral cortex 1 Low
Cervix, uterine 1 Low
Colon 2 Medium
Duodenum 1 Low
Endometrium 1 Low
Epididymis 0 Not detected
Esophagus 2 Medium
Fallopian tube 0 Not detected
Gallbladder 0 Not detected
Heart muscle 1 Low
Hippocampus 0 Not detected
Kidney 0 Not detected
Liver 0 Not detected
Lung 0 Not detected
Lymph node 3 High
Nasopharynx 1 Low
Oral mucosa 1 Low
Ovary 0 Not detected
Pancreas 1 Low
Parathyroid gland 2 Medium
Placenta 2 Medium
Prostate 2 Medium
Rectum 1 Low
Salivary gland 0 Not detected
Seminal vesicle 2 Medium
Skeletal muscle 1 Low
Skin 2 Medium
Small intestine 0 Not detected
Smooth muscle 2 Medium
Soft tissue 2 Medium
Spleen 2 Medium
Stomach 1 Low
Testis 1 Low
Thyroid gland 0 Not detected
Tonsil 2 Medium
Urinary bladder 1 Low
Vagina 2 Medium
Summary
SymbolSETD7
NameSET domain containing lysine methyltransferase 7
Aliases KIAA1717; SET7/9; Set9; KMT7; H3-K4-HMTase SETD7; SET domain-containing protein 7; histone H3-K4 methyltrans ......
Location4q31.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Association between expresson and subtype
> Overall survival analysis based on expression
> Association between expresson and stage
> Association between expresson and grade
> Subtype
 


  Association between expresson and subtype.
Cancer Full Name # Patients P Value (Kruskal-Wallis) Association Source
BLCABladder urothelial carcinoma1280.0968NS24476821
BRCABreast invasive carcinoma5211.44e-17Significant23000897
COADColon adenocarcinoma1490.00011Significant22810696
GBMGlioblastoma multiforme1570.000297Significant26824661
HNSCHead and Neck squamous cell carcinoma2790.357NS25631445
KIRPKidney renal papillary cell carcinoma1610.128NS26536169
LGGBrain Lower Grade Glioma5132.09e-06Significant26824661
LUADLung adenocarcinoma2300.317NS25079552
LUSCLung squamous cell carcinoma1783.4e-05Significant22960745
OVOvarian serous cystadenocarcinoma2875.87e-12Significant21720365
PRADProstate adenocarcinoma3330.449NS26544944
READRectum adenocarcinoma670.261NS22810696
SKCMSkin Cutaneous Melanoma3150.0372Significant26091043
STADStomach adenocarcinoma2771.24e-11Significant25079317
THCAThyroid carcinoma3917.42e-10Significant25417114
UCECUterine Corpus Endometrial Carcinoma2320.00282Significant23636398
> Overall survival
 

  Overall survival analysis based on expression.
Cancer Full Name # Patients Hazard Ratio P Value (Log Rank Test) Association
BLCABladder urothelial carcinoma405 1.7110.016Shorter
BRCABreast invasive carcinoma1079 1.6470.0347Shorter
CESCCervical and endocervical cancers291 1.6940.117NS
COADColon adenocarcinoma439 0.7340.3NS
ESCAEsophageal carcinoma184 0.6360.165NS
GBMGlioblastoma multiforme158 0.830.465NS
HNSCHead and Neck squamous cell carcinoma518 1.1210.576NS
KIRCKidney renal clear cell carcinoma531 0.7650.204NS
KIRPKidney renal papillary cell carcinoma287 0.9260.855NS
LAMLAcute Myeloid Leukemia149 1.570.126NS
LGGBrain Lower Grade Glioma511 0.7840.34NS
LIHCLiver hepatocellular carcinoma365 0.6910.127NS
LUADLung adenocarcinoma502 1.2390.281NS
LUSCLung squamous cell carcinoma494 0.9790.918NS
OVOvarian serous cystadenocarcinoma303 1.2010.367NS
PAADPancreatic adenocarcinoma177 1.2470.437NS
PCPGPheochromocytoma and Paraganglioma179 654539252.6820.0698NS
PRADProstate adenocarcinoma497 00.295NS
READRectum adenocarcinoma159 3.0490.0766NS
SARCSarcoma259 0.4250.00309Longer
SKCMSkin Cutaneous Melanoma459 0.6840.0496Longer
STADStomach adenocarcinoma388 1.4680.0813NS
TGCTTesticular Germ Cell Tumors134 554428971.1480.335NS
THCAThyroid carcinoma500 1.20.778NS
THYMThymoma119 5.7050.0793NS
UCECUterine Corpus Endometrial Carcinoma543 0.880.666NS
> Stage
 

  Association between expresson and stage.
Cancer Full Name # Patients R Value (Spearman) P Value (Spearman) Association
BLCABladder urothelial carcinoma406 0.1680.000665Higher
BRCABreast invasive carcinoma1071 -0.0050.883NS
CESCCervical and endocervical cancers167 -0.0160.839NS
COADColon adenocarcinoma445 -0.060.207NS
ESCAEsophageal carcinoma162 -0.110.162NS
HNSCHead and Neck squamous cell carcinoma448 0.0220.641NS
KIRCKidney renal clear cell carcinoma531 -0.1250.00395Lower
KIRPKidney renal papillary cell carcinoma260 0.0040.949NS
LIHCLiver hepatocellular carcinoma347 -0.0270.611NS
LUADLung adenocarcinoma507 0.1250.0047Higher
LUSCLung squamous cell carcinoma497 0.0830.0643NS
OVOvarian serous cystadenocarcinoma302 00.993NS
PAADPancreatic adenocarcinoma176 0.0750.324NS
READRectum adenocarcinoma156 0.0970.228NS
SKCMSkin Cutaneous Melanoma410 0.0480.327NS
STADStomach adenocarcinoma392 0.0950.0593NS
TGCTTesticular Germ Cell Tumors81 0.1890.0908NS
THCAThyroid carcinoma499 0.1190.00759Higher
UCECUterine Corpus Endometrial Carcinoma501 -0.0360.427NS
> Grade
 

  Association between expresson and grade.
Cancer Full Name # Patients R Value (Spearman) P Value (Spearman) Association
CESCCervical and endocervical cancers272 -0.1360.025Lower
HNSCHead and Neck squamous cell carcinoma498 -0.0460.303NS
KIRCKidney renal clear cell carcinoma525 -0.0970.0263Lower
LGGBrain Lower Grade Glioma514 -0.0890.0448Lower
LIHCLiver hepatocellular carcinoma366 -0.2642.98e-07Lower
OVOvarian serous cystadenocarcinoma296 -0.1040.0728NS
PAADPancreatic adenocarcinoma176 -0.0440.566NS
STADStomach adenocarcinoma406 0.0820.0977NS
UCECUterine Corpus Endometrial Carcinoma534 -0.0720.0966NS
Summary
SymbolSETD7
NameSET domain containing lysine methyltransferase 7
Aliases KIAA1717; SET7/9; Set9; KMT7; H3-K4-HMTase SETD7; SET domain-containing protein 7; histone H3-K4 methyltrans ......
Location4q31.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Targets inferred by reverse engineering method
> Targets identified by ChIP-seq data
> Targets inferred by reverse engineering method
 
> Targets identified by ChIP-seq data
 
Summary
SymbolSETD7
NameSET domain containing lysine methyltransferase 7
Aliases KIAA1717; SET7/9; Set9; KMT7; H3-K4-HMTase SETD7; SET domain-containing protein 7; histone H3-K4 methyltrans ......
Location4q31.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Drugs from DrugBank database
> Drugs from DrugBank database
 
DrugBank ID Name Type All Targets
DB01752S-Adenosyl-L-HomocysteineSmall Molecule Drug
Summary
SymbolSETD7
NameSET domain containing lysine methyltransferase 7
Aliases KIAA1717; SET7/9; Set9; KMT7; H3-K4-HMTase SETD7; SET domain-containing protein 7; histone H3-K4 methyltrans ......
Location4q31.1
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Protein-Protein Interaction Network
> miRNA Regulatory Relationship
> Interactions from Text Mining
> Protein-Protein Interaction Network
 
> miRNA Regulatory Relationship
 
> Interactions from Text Mining
 
There is no record for SETD7.