Browse SMNDC1 in pancancer

Summary
Symbol	SMNDC1
Name	survival motor neuron domain containing 1
Aliases	SPF30; SMNR; TDRD16C; splicing factor 30, survival of motor neuron-related; tudor domain containing 16C; 30 ......
Location	10q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

Domain

PF06003 Survival motor neuron protein (SMN)

Function

Necessary for spliceosome assembly. Overexpression causes apoptosis.

Classification

Class	Modification	Substrate	Product	PubMed
#	#	#	#	#

> Gene Ontology [ TOP ]
Biological Process	GO:0000375 RNA splicing, via transesterification reactions GO:0006397 mRNA processing GO:0008380 RNA splicing
Molecular Function	-
Cellular Component	GO:0005681 spliceosomal complex GO:0015030 Cajal body GO:0016604 nuclear body GO:0016607 nuclear speck

> KEGG and Reactome Pathway [ TOP ]
KEGG	hsa03040 Spliceosome
Reactome	R-HSA-74160: Gene Expression R-HSA-72203: Processing of Capped Intron-Containing Pre-mRNA R-HSA-72172: mRNA Splicing R-HSA-72163: mRNA Splicing - Major Pathway

Summary
Symbol	SMNDC1
Name	survival motor neuron domain containing 1
Aliases	SPF30; SMNR; TDRD16C; splicing factor 30, survival of motor neuron-related; tudor domain containing 16C; 30 ......
Location	10q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM4551423	c.528G>T	p.V176V	Substitution - coding silent	Skin
COSM5729946	c.465G>A	p.K155K	Substitution - coding silent	Skin
COSM4011550	c.310G>A	p.A104T	Substitution - Missense	Stomach
COSM4936410	c.717A>G	p.239	Substitution - coding silent	Liver
COSM3769074	c.663G>C	p.M221I	Substitution - Missense	Pancreas
COSM326519	c.184G>C	p.D62H	Substitution - Missense	Lung
COSM106677	c.567C>A	p.N189K	Substitution - Missense	Skin
COSM914725	c.24G>A	p.Q8Q	Substitution - coding silent	Endometrium
COSM2061108	c.408C>T	p.G136G	Substitution - coding silent	Large_intestine
COSM306097	c.275C>T	p.A92V	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM306097	c.275C>T	p.A92V	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4011549	c.657A>C	p.K219N	Substitution - Missense	Stomach
COSM1627308	c.207T>C	p.P69P	Substitution - coding silent	Liver
COSM1226875	c.512G>T	p.R171I	Substitution - Missense	Large_intestine
COSM5649106	c.658C>T	p.P220S	Substitution - Missense	Oesophagus
COSM326519	c.184G>C	p.D62H	Substitution - Missense	Cervix
COSM3806425	c.74G>A	p.G25E	Substitution - Missense	Breast
COSM4635832	c.286G>A	p.E96K	Substitution - Missense	Large_intestine
COSM4925547	c.54A>G	p.Q18Q	Substitution - coding silent	Liver
COSM3978078	c.406G>A	p.G136S	Substitution - Missense	Lung
COSM4011551	c.170C>T	p.T57M	Substitution - Missense	Stomach
COSM5979980	c.121-2_121-1insAT	p.?	Unknown	Upper_aerodigestive_tract
COSM1664283	c.388A>G	p.K130E	Substitution - Missense	Kidney
COSM4553255	c.585G>A	p.K195K	Substitution - coding silent	Skin
COSM4916059	c.6A>G	p.S2S	Substitution - coding silent	Liver
COSM5745097	c.449G>A	p.R150H	Substitution - Missense	Pancreas

> Text Mining based Variations [ TOP ]
There is no record for SMNDC1.

Summary
Symbol	SMNDC1
Name	survival motor neuron domain containing 1
Aliases	SPF30; SMNR; TDRD16C; splicing factor 30, survival of motor neuron-related; tudor domain containing 16C; 30 ......
Location	10q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant
O75940	219	K	N6-acetyllysine	-	Yes	p.K219N (cancer: STAD)

Summary
Symbol	SMNDC1
Name	survival motor neuron domain containing 1
Aliases	SPF30; SMNR; TDRD16C; splicing factor 30, survival of motor neuron-related; tudor domain containing 16C; 30 ......
Location	10q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	5.049	5.135	0.118	0.33	NS
BRCA	Breast invasive carcinoma	112	1100	4.908	5.051	0.153	0.000188	NS
CESC	Cervical and endocervical cancers	3	306	5.306	5.418	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	4.784	5.161	0.317	0.00132	NS
ESCA	Esophageal carcinoma	11	185	4.492	5.085	0.523	7.46e-05	NS
GBM	Glioblastoma multiforme	5	166	4.485	4.707	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	5.047	5.192	0.195	0.00685	NS
KIRC	Kidney renal clear cell carcinoma	72	534	4.889	4.901	0.023	0.631	NS
KIRP	Kidney renal papillary cell carcinoma	32	291	4.606	4.723	0.122	0.0891	NS
LAML	Acute Myeloid Leukemia	0	173	NA	5.424	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	4.539	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	4.025	3.89	-0.143	0.0252	NS
LUAD	Lung adenocarcinoma	59	517	4.875	5.076	0.189	0.00139	NS
LUSC	Lung squamous cell carcinoma	51	501	4.749	5.361	0.566	9.4e-17	NS
OV	Ovarian serous cystadenocarcinoma	0	307	NA	5.233	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	4.956	4.964	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	4.946	4.61	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	4.731	4.611	-0.136	0.00792	NS
READ	Rectum adenocarcinoma	10	167	4.991	5.058	-0.093	0.732	NS
SARC	Sarcoma	2	263	4.787	5.004	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	5.111	4.848	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	4.544	4.937	0.384	6.84e-06	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	5.316	NA	NA	NA
THCA	Thyroid carcinoma	59	509	4.957	4.882	-0.072	0.0628	NS
THYM	Thymoma	2	120	5.162	5.164	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	5.108	4.957	-0.185	0.13	NS

> Cancer Cell Line Encyclopedia (CCLE)

Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	10.6
Autonomic ganglia	CHP212	10.5
Autonomic ganglia	IMR32	10.6
Autonomic ganglia	KELLY	11
Autonomic ganglia	KPNRTBM1	10.5
Autonomic ganglia	KPNSI9S	10.4
Autonomic ganglia	KPNYN	9.6
Autonomic ganglia	MHHNB11	11.2
Autonomic ganglia	NB1	10.7
Autonomic ganglia	NH6	9.9
Autonomic ganglia	SHSY5Y	11
Autonomic ganglia	SIMA	10.9
Autonomic ganglia	SKNAS	10.5
Autonomic ganglia	SKNBE2	10.5
Autonomic ganglia	SKNDZ	10.8
Autonomic ganglia	SKNFI	10.7
Autonomic ganglia	SKNSH	10.3
Biliary tract	HUCCT1	10.4
Biliary tract	HUH28	10
Biliary tract	SNU1079	10.3
Biliary tract	SNU1196	11.1
Biliary tract	SNU245	9.5
Biliary tract	SNU308	9.6
Biliary tract	SNU478	10.8
Bone	143B	11.1
Bone	A673	10.4
Bone	CADOES1	10.9
Bone	CAL78	10.5
Bone	G292CLONEA141B1	10.8
Bone	HOS	11.1
Bone	HS706T	9.9
Bone	HS737T	10.1
Bone	HS819T	10.1
Bone	HS821T	10
Bone	HS822T	9.8
Bone	HS863T	10.3
Bone	HS870T	10
Bone	HS888T	10.4
Bone	MG63	10.9
Bone	MHHES1	10.9
Bone	OUMS27	10.3
Bone	RDES	10.2
Bone	SJSA1	10.5
Bone	SKES1	10.6
Bone	SKNMC	10.1
Bone	SW1353	10.1
Bone	T173	9.8
Bone	TC71	10.5
Bone	U2OS	10.5
Breast	AU565	9.5
Breast	BT20	9.4
Breast	BT474	9.6
Breast	BT483	10
Breast	BT549	9.8
Breast	CAL120	10.5
Breast	CAL148	10.7
Breast	CAL51	10.5
Breast	CAL851	9.8
Breast	CAMA1	10.4
Breast	DU4475	10
Breast	EFM192A	10.3
Breast	EFM19	10
Breast	EVSAT	9.9
Breast	HCC1143	10.2
Breast	HCC1187	10.5
Breast	HCC1395	10.3
Breast	HCC1419	10
Breast	HCC1428	11.1
Breast	HCC1500	9.8
Breast	HCC1569	10.2
Breast	HCC1599	10.3
Breast	HCC1806	10.6
Breast	HCC1937	9.9
Breast	HCC1954	10.2
Breast	HCC202	10
Breast	HCC2157	10.2
Breast	HCC2218	9.8
Breast	HCC38	9.7
Breast	HCC70	10
Breast	HDQP1	10.7
Breast	HMC18	10.6
Breast	HS274T	10.2
Breast	HS281T	10.3
Breast	HS343T	10.2
Breast	HS578T	10.2
Breast	HS606T	10.2
Breast	HS739T	9.9
Breast	HS742T	9.9
Breast	JIMT1	10.6
Breast	KPL1	10.5
Breast	MCF7	10.2
Breast	MDAMB134VI	10.5
Breast	MDAMB157	10.2
Breast	MDAMB175VII	9.7
Breast	MDAMB231	10.5
Breast	MDAMB361	10.6
Breast	MDAMB415	11.1
Breast	MDAMB436	10.5
Breast	MDAMB453	10.7
Breast	MDAMB468	10.2
Breast	SKBR3	9.7
Breast	T47D	10.1
Breast	UACC812	10.3
Breast	UACC893	10
Breast	YMB1	10.2
Breast	ZR751	10.5
Breast	ZR7530	10.4
Central nervous system	1321N1	10.6
Central nervous system	42MGBA	10.7
Central nervous system	8MGBA	10.2
Central nervous system	A172	10.6
Central nervous system	AM38	10.7
Central nervous system	BECKER	10.1
Central nervous system	CAS1	10.1
Central nervous system	CCFSTTG1	10
Central nervous system	D283MED	11.2
Central nervous system	D341MED	10.5
Central nervous system	DAOY	10.8
Central nervous system	DBTRG05MG	10.1
Central nervous system	DKMG	9.6
Central nervous system	GAMG	10.1
Central nervous system	GB1	11
Central nervous system	GI1	10.6
Central nervous system	GMS10	10.4
Central nervous system	GOS3	9.4
Central nervous system	H4	10.7
Central nervous system	HS683	9.9
Central nervous system	KALS1	10.6
Central nervous system	KG1C	10.1
Central nervous system	KNS42	10.5
Central nervous system	KNS60	10.7
Central nervous system	KNS81	9.4
Central nervous system	KS1	10.6
Central nervous system	LN18	10.6
Central nervous system	LN229	10
Central nervous system	M059K	10.1
Central nervous system	MOGGCCM	10
Central nervous system	MOGGUVW	10.2
Central nervous system	NMCG1	10.3
Central nervous system	ONS76	9.8
Central nervous system	SF126	10.8
Central nervous system	SF295	9.9
Central nervous system	SNB19	10.8
Central nervous system	SNU1105	10.5
Central nervous system	SNU201	9.5
Central nervous system	SNU466	9.7
Central nervous system	SNU489	9.2
Central nervous system	SNU626	10.4
Central nervous system	SNU738	10.4
Central nervous system	SW1088	10.2
Central nervous system	SW1783	10
Central nervous system	T98G	9.8
Central nervous system	TM31	10.9
Central nervous system	U118MG	10.1
Central nervous system	U138MG	10.6
Central nervous system	U251MG	10.4
Central nervous system	U87MG	10
Central nervous system	YH13	9.5
Central nervous system	YKG1	10.7
Endometrium	AN3CA	10.8
Endometrium	COLO684	10.3
Endometrium	EFE184	10.1
Endometrium	EN	10.8
Endometrium	ESS1	10.7
Endometrium	HEC108	10.2
Endometrium	HEC151	10.9
Endometrium	HEC1A	10.7
Endometrium	HEC1B	10.5
Endometrium	HEC251	10.6
Endometrium	HEC265	10.5
Endometrium	HEC50B	10.9
Endometrium	HEC59	10.9
Endometrium	HEC6	10.6
Endometrium	ISHIKAWAHERAKLIO02ER	10.7
Endometrium	JHUEM1	10.3
Endometrium	JHUEM2	11.4
Endometrium	JHUEM3	11
Endometrium	KLE	9.9
Endometrium	MFE280	10.1
Endometrium	MFE296	10.2
Endometrium	MFE319	10.2
Endometrium	RL952	10.2
Endometrium	SNGM	10.7
Endometrium	SNU1077	10.3
Endometrium	SNU685	10.8
Endometrium	TEN	10.5
Haematopoietic and lymphoid	697	11.1
Haematopoietic and lymphoid	A3KAW	11.5
Haematopoietic and lymphoid	A4FUK	9.8
Haematopoietic and lymphoid	ALLSIL	11.2
Haematopoietic and lymphoid	AML193	10.6
Haematopoietic and lymphoid	AMO1	10.9
Haematopoietic and lymphoid	BCP1	10.6
Haematopoietic and lymphoid	BDCM	10.9
Haematopoietic and lymphoid	BL41	11.4
Haematopoietic and lymphoid	BL70	10.9
Haematopoietic and lymphoid	BV173	11.4
Haematopoietic and lymphoid	CA46	10.9
Haematopoietic and lymphoid	CI1	10.9
Haematopoietic and lymphoid	CMK115	10.9
Haematopoietic and lymphoid	CMK86	10.9
Haematopoietic and lymphoid	CMK	10
Haematopoietic and lymphoid	CMLT1	10.6
Haematopoietic and lymphoid	COLO775	10.1
Haematopoietic and lymphoid	DAUDI	10.8
Haematopoietic and lymphoid	DB	9.9
Haematopoietic and lymphoid	DEL	10.3
Haematopoietic and lymphoid	DND41	11.3
Haematopoietic and lymphoid	DOHH2	10.8
Haematopoietic and lymphoid	EB1	10.8
Haematopoietic and lymphoid	EB2	10.7
Haematopoietic and lymphoid	EHEB	10.5
Haematopoietic and lymphoid	EJM	10.1
Haematopoietic and lymphoid	EM2	11
Haematopoietic and lymphoid	EOL1	11.1
Haematopoietic and lymphoid	F36P	10.9
Haematopoietic and lymphoid	GA10	11.1
Haematopoietic and lymphoid	GDM1	10.8
Haematopoietic and lymphoid	GRANTA519	11
Haematopoietic and lymphoid	HDLM2	10.6
Haematopoietic and lymphoid	HDMYZ	10.6
Haematopoietic and lymphoid	HEL9217	11
Haematopoietic and lymphoid	HEL	11
Haematopoietic and lymphoid	HH	10.6
Haematopoietic and lymphoid	HL60	10.5
Haematopoietic and lymphoid	HPBALL	11.2
Haematopoietic and lymphoid	HS604T	9.5
Haematopoietic and lymphoid	HS611T	10.6
Haematopoietic and lymphoid	HS616T	10
Haematopoietic and lymphoid	HS751T	10.9
Haematopoietic and lymphoid	HT	11.4
Haematopoietic and lymphoid	HTK	10.9
Haematopoietic and lymphoid	HUNS1	10.5
Haematopoietic and lymphoid	HUT102	10.3
Haematopoietic and lymphoid	HUT78	9.9
Haematopoietic and lymphoid	JEKO1	11.2
Haematopoietic and lymphoid	JK1	10.6
Haematopoietic and lymphoid	JM1	11.4
Haematopoietic and lymphoid	JURKAT	11.4
Haematopoietic and lymphoid	JURLMK1	11.2
Haematopoietic and lymphoid	JVM2	11
Haematopoietic and lymphoid	JVM3	10.7
Haematopoietic and lymphoid	K562	9.9
Haematopoietic and lymphoid	KARPAS299	10.3
Haematopoietic and lymphoid	KARPAS422	11
Haematopoietic and lymphoid	KARPAS620	10.6
Haematopoietic and lymphoid	KASUMI1	11.5
Haematopoietic and lymphoid	KASUMI2	10.7
Haematopoietic and lymphoid	KASUMI6	10.9
Haematopoietic and lymphoid	KCL22	11.1
Haematopoietic and lymphoid	KE37	11.1
Haematopoietic and lymphoid	KE97	10.4
Haematopoietic and lymphoid	KG1	10.8
Haematopoietic and lymphoid	KHM1B	10.1
Haematopoietic and lymphoid	KIJK	10.9
Haematopoietic and lymphoid	KMH2	10.3
Haematopoietic and lymphoid	KMM1	11.1
Haematopoietic and lymphoid	KMS11	10.7
Haematopoietic and lymphoid	KMS12BM	10.2
Haematopoietic and lymphoid	KMS18	10.9
Haematopoietic and lymphoid	KMS20	10.5
Haematopoietic and lymphoid	KMS21BM	10.5
Haematopoietic and lymphoid	KMS26	10.7
Haematopoietic and lymphoid	KMS27	10.3
Haematopoietic and lymphoid	KMS28BM	10.6
Haematopoietic and lymphoid	KMS34	10.3
Haematopoietic and lymphoid	KO52	10.8
Haematopoietic and lymphoid	KOPN8	10.6
Haematopoietic and lymphoid	KU812	10.8
Haematopoietic and lymphoid	KYO1	10.3
Haematopoietic and lymphoid	L1236	10.8
Haematopoietic and lymphoid	L363	11.5
Haematopoietic and lymphoid	L428	11.1
Haematopoietic and lymphoid	L540	10.6
Haematopoietic and lymphoid	LAMA84	11
Haematopoietic and lymphoid	LOUCY	10.8
Haematopoietic and lymphoid	LP1	10.9
Haematopoietic and lymphoid	M07E	11.1
Haematopoietic and lymphoid	MC116	10.9
Haematopoietic and lymphoid	ME1	10.5
Haematopoietic and lymphoid	MEC1	11.3
Haematopoietic and lymphoid	MEC2	10.5
Haematopoietic and lymphoid	MEG01	10.1
Haematopoietic and lymphoid	MHHCALL2	10.9
Haematopoietic and lymphoid	MHHCALL3	10.8
Haematopoietic and lymphoid	MHHCALL4	10.7
Haematopoietic and lymphoid	MINO	11.1
Haematopoietic and lymphoid	MJ	11.1
Haematopoietic and lymphoid	MM1S	10.6
Haematopoietic and lymphoid	MOLM13	10.5
Haematopoietic and lymphoid	MOLM16	11
Haematopoietic and lymphoid	MOLM6	10.9
Haematopoietic and lymphoid	MOLP2	9.6
Haematopoietic and lymphoid	MOLP8	9.9
Haematopoietic and lymphoid	MOLT13	11.3
Haematopoietic and lymphoid	MOLT16	10.8
Haematopoietic and lymphoid	MOLT4	10.9
Haematopoietic and lymphoid	MONOMAC1	9.8
Haematopoietic and lymphoid	MONOMAC6	10.9
Haematopoietic and lymphoid	MOTN1	11
Haematopoietic and lymphoid	MUTZ5	10.7
Haematopoietic and lymphoid	MV411	10.6
Haematopoietic and lymphoid	NALM19	10.9
Haematopoietic and lymphoid	NALM1	10.8
Haematopoietic and lymphoid	NALM6	11.2
Haematopoietic and lymphoid	NAMALWA	10.5
Haematopoietic and lymphoid	NB4	11.6
Haematopoietic and lymphoid	NCIH929	10.4
Haematopoietic and lymphoid	NCO2	11.4
Haematopoietic and lymphoid	NOMO1	11.1
Haematopoietic and lymphoid	NUDHL1	11
Haematopoietic and lymphoid	NUDUL1	10.9
Haematopoietic and lymphoid	OCIAML2	11
Haematopoietic and lymphoid	OCIAML3	10.6
Haematopoietic and lymphoid	OCIAML5	10.7
Haematopoietic and lymphoid	OCILY10	10.9
Haematopoietic and lymphoid	OCILY19	11.6
Haematopoietic and lymphoid	OCILY3	10.6
Haematopoietic and lymphoid	OCIM1	11.6
Haematopoietic and lymphoid	OPM2	10.9
Haematopoietic and lymphoid	P12ICHIKAWA	11.2
Haematopoietic and lymphoid	P31FUJ	10.7
Haematopoietic and lymphoid	P3HR1	10.6
Haematopoietic and lymphoid	PCM6	10.5
Haematopoietic and lymphoid	PEER	11.2
Haematopoietic and lymphoid	PF382	11
Haematopoietic and lymphoid	PFEIFFER	11.1
Haematopoietic and lymphoid	PL21	10.6
Haematopoietic and lymphoid	RAJI	10.8
Haematopoietic and lymphoid	RCHACV	11.2
Haematopoietic and lymphoid	REC1	11.2
Haematopoietic and lymphoid	REH	11.1
Haematopoietic and lymphoid	RI1	11.1
Haematopoietic and lymphoid	RL	10.8
Haematopoietic and lymphoid	RPMI8226	10.3
Haematopoietic and lymphoid	RPMI8402	11.2
Haematopoietic and lymphoid	RS411	10.6
Haematopoietic and lymphoid	SEM	10.6
Haematopoietic and lymphoid	SET2	10.8
Haematopoietic and lymphoid	SIGM5	10.4
Haematopoietic and lymphoid	SKM1	11.1
Haematopoietic and lymphoid	SKMM2	10.6
Haematopoietic and lymphoid	SR786	10.6
Haematopoietic and lymphoid	ST486	11
Haematopoietic and lymphoid	SUDHL10	10.4
Haematopoietic and lymphoid	SUDHL1	10.8
Haematopoietic and lymphoid	SUDHL4	10.7
Haematopoietic and lymphoid	SUDHL5	11.3
Haematopoietic and lymphoid	SUDHL6	10.9
Haematopoietic and lymphoid	SUDHL8	11.4
Haematopoietic and lymphoid	SUPB15	10.5
Haematopoietic and lymphoid	SUPHD1	10.7
Haematopoietic and lymphoid	SUPM2	11.6
Haematopoietic and lymphoid	SUPT11	10.2
Haematopoietic and lymphoid	SUPT1	10.8
Haematopoietic and lymphoid	TALL1	11.2
Haematopoietic and lymphoid	TF1	11.6
Haematopoietic and lymphoid	THP1	10
Haematopoietic and lymphoid	TO175T	10.1
Haematopoietic and lymphoid	TOLEDO	10.6
Haematopoietic and lymphoid	U266B1	10.8
Haematopoietic and lymphoid	U937	11.2
Haematopoietic and lymphoid	UT7	10.4
Haematopoietic and lymphoid	WSUDLCL2	10.5
Kidney	769P	10.2
Kidney	786O	10.5
Kidney	A498	10.1
Kidney	A704	10.4
Kidney	ACHN	10.9
Kidney	BFTC909	11.1
Kidney	CAKI1	10.4
Kidney	CAKI2	10.3
Kidney	CAL54	10.4
Kidney	KMRC1	10.6
Kidney	KMRC20	10.8
Kidney	KMRC2	10.2
Kidney	KMRC3	9.9
Kidney	OSRC2	11
Kidney	RCC10RGB	10.4
Kidney	SNU1272	10.9
Kidney	SNU349	9.5
Kidney	TUHR10TKB	10.7
Kidney	TUHR14TKB	9
Kidney	TUHR4TKB	10
Kidney	VMRCRCW	9.7
Kidney	VMRCRCZ	10.5
Large intestine	C2BBE1	11
Large intestine	CCK81	10.7
Large intestine	CL11	11.2
Large intestine	CL14	10.9
Large intestine	CL34	10.8
Large intestine	CL40	10.1
Large intestine	COLO205	10.3
Large intestine	COLO320	10.2
Large intestine	COLO678	11.2
Large intestine	CW2	10.9
Large intestine	DLD1	10.8
Large intestine	GP2D	11.1
Large intestine	HCC56	10.6
Large intestine	HCT116	11.5
Large intestine	HCT15	10.6
Large intestine	HS675T	9.9
Large intestine	HS698T	10.1
Large intestine	HT115	11
Large intestine	HT29	10.2
Large intestine	HT55	10.5
Large intestine	KM12	10.5
Large intestine	LOVO	10.7
Large intestine	LS1034	10.6
Large intestine	LS123	10.3
Large intestine	LS180	10.6
Large intestine	LS411N	10.5
Large intestine	LS513	10.8
Large intestine	MDST8	10.9
Large intestine	NCIH508	9.4
Large intestine	NCIH716	10.2
Large intestine	NCIH747	10.5
Large intestine	OUMS23	10.5
Large intestine	RCM1	10.5
Large intestine	RKO	11.7
Large intestine	SKCO1	10.5
Large intestine	SNU1040	11
Large intestine	SNU1197	10.5
Large intestine	SNU175	10.3
Large intestine	SNU283	10.4
Large intestine	SNU407	10.2
Large intestine	SNU503	10.5
Large intestine	SNU61	10.7
Large intestine	SNU81	10.6
Large intestine	SNUC1	9.9
Large intestine	SNUC2A	10.6
Large intestine	SNUC4	10.9
Large intestine	SNUC5	11.2
Large intestine	SW1116	10.2
Large intestine	SW1417	10.6
Large intestine	SW1463	10.4
Large intestine	SW403	10.3
Large intestine	SW480	10.1
Large intestine	SW48	10.9
Large intestine	SW620	10.6
Large intestine	SW837	11.5
Large intestine	SW948	10
Large intestine	T84	9.9
Liver	ALEXANDERCELLS	10.4
Liver	C3A	10.5
Liver	HEP3B217	10.7
Liver	HEPG2	10.1
Liver	HLE	10.8
Liver	HLF	10.7
Liver	HUH1	10.5
Liver	HUH6	11.3
Liver	HUH7	10.4
Liver	JHH1	9.9
Liver	JHH2	10.3
Liver	JHH4	10.6
Liver	JHH5	10.2
Liver	JHH6	10.8
Liver	JHH7	9.8
Liver	LI7	10.8
Liver	PLCPRF5	10.3
Liver	SKHEP1	11
Liver	SNU182	10.5
Liver	SNU387	10.4
Liver	SNU398	11.5
Liver	SNU423	10.8
Liver	SNU449	10.6
Liver	SNU475	10
Liver	SNU761	10
Liver	SNU878	10
Liver	SNU886	10.4
Lung	A549	10.7
Lung	ABC1	10.6
Lung	BEN	9.1
Lung	CAL12T	10.3
Lung	CALU1	9.9
Lung	CALU3	9.9
Lung	CALU6	10.2
Lung	CHAGOK1	9.7
Lung	COLO668	10.1
Lung	COLO699	10.5
Lung	CORL105	10.3
Lung	CORL23	10.5
Lung	CORL24	10.8
Lung	CORL279	9.7
Lung	CORL311	11.1
Lung	CORL47	10.5
Lung	CORL51	10.5
Lung	CORL88	10.4
Lung	CORL95	10.2
Lung	CPCN	10.5
Lung	DMS114	11
Lung	DMS153	10.2
Lung	DMS273	10.7
Lung	DMS454	11.6
Lung	DMS53	10
Lung	DMS79	10.3
Lung	DV90	10.4
Lung	EBC1	10.1
Lung	EPLC272H	10.2
Lung	HARA	10.8
Lung	HCC1171	11
Lung	HCC1195	10.4
Lung	HCC15	10.6
Lung	HCC2279	10.5
Lung	HCC2935	10.5
Lung	HCC33	10.4
Lung	HCC366	11.7
Lung	HCC4006	10.6
Lung	HCC44	10.2
Lung	HCC78	10.4
Lung	HCC827	10.3
Lung	HCC95	11.2
Lung	HLC1	10.5
Lung	HLFA	10.3
Lung	HS229T	10.4
Lung	HS618T	10.4
Lung	IALM	10.1
Lung	KNS62	10.3
Lung	LC1F	10.2
Lung	LC1SQSF	11.5
Lung	LCLC103H	10.3
Lung	LCLC97TM1	10.5
Lung	LK2	10.1
Lung	LOUNH91	9.9
Lung	LU65	10.5
Lung	LU99	11.2
Lung	LUDLU1	10.5
Lung	LXF289	11
Lung	MORCPR	10.4
Lung	NCIH1048	10.9
Lung	NCIH1092	11.1
Lung	NCIH1105	10.5
Lung	NCIH1155	10.7
Lung	NCIH1184	10.2
Lung	NCIH1299	10.3
Lung	NCIH1339	10.4
Lung	NCIH1341	10.3
Lung	NCIH1355	10.3
Lung	NCIH1373	10.6
Lung	NCIH1385	10.2
Lung	NCIH1395	8.8
Lung	NCIH1435	11.7
Lung	NCIH1436	11.3
Lung	NCIH1437	10.2
Lung	NCIH146	10.5
Lung	NCIH1563	9.8
Lung	NCIH1568	10
Lung	NCIH1573	10
Lung	NCIH1581	11.1
Lung	NCIH1618	10.4
Lung	NCIH1623	9.9
Lung	NCIH1648	10.3
Lung	NCIH1650	10.7
Lung	NCIH1651	9.7
Lung	NCIH1666	10.5
Lung	NCIH1693	10.5
Lung	NCIH1694	10.4
Lung	NCIH1703	10.7
Lung	NCIH1734	10.2
Lung	NCIH1755	10.8
Lung	NCIH1781	10.5
Lung	NCIH1792	10.1
Lung	NCIH1793	10.2
Lung	NCIH1836	10.5
Lung	NCIH1838	10.1
Lung	NCIH1869	11
Lung	NCIH1876	10.6
Lung	NCIH1915	11.3
Lung	NCIH1930	9.8
Lung	NCIH1944	10.7
Lung	NCIH1963	10.5
Lung	NCIH196	10.9
Lung	NCIH1975	10.5
Lung	NCIH2009	10.9
Lung	NCIH2023	10.7
Lung	NCIH2029	9.4
Lung	NCIH2030	10.7
Lung	NCIH2066	10.1
Lung	NCIH2081	10.6
Lung	NCIH2085	9.8
Lung	NCIH2087	10.4
Lung	NCIH209	10.4
Lung	NCIH2106	10.3
Lung	NCIH2110	11.5
Lung	NCIH211	10.1
Lung	NCIH2122	10.5
Lung	NCIH2126	9.6
Lung	NCIH2141	10.1
Lung	NCIH2170	10
Lung	NCIH2171	10.2
Lung	NCIH2172	10.8
Lung	NCIH2196	9.5
Lung	NCIH2227	10.6
Lung	NCIH2228	10.3
Lung	NCIH226	11
Lung	NCIH2286	11.3
Lung	NCIH2291	10.7
Lung	NCIH2342	10.4
Lung	NCIH2347	10.4
Lung	NCIH23	10.4
Lung	NCIH2405	10.8
Lung	NCIH2444	10.4
Lung	NCIH292	10.1
Lung	NCIH322	11
Lung	NCIH3255	9.8
Lung	NCIH358	10.3
Lung	NCIH441	9.8
Lung	NCIH446	10.3
Lung	NCIH460	11.2
Lung	NCIH510	10.4
Lung	NCIH520	10.4
Lung	NCIH522	10.4
Lung	NCIH524	10
Lung	NCIH526	9.9
Lung	NCIH596	10.2
Lung	NCIH647	10.5
Lung	NCIH650	10.8
Lung	NCIH661	10.4
Lung	NCIH69	9.8
Lung	NCIH727	10.2
Lung	NCIH810	10.4
Lung	NCIH82	10.9
Lung	NCIH838	11.1
Lung	NCIH841	10.5
Lung	NCIH854	10.3
Lung	NCIH889	9.9
Lung	PC14	9.9
Lung	RERFLCAD1	10.6
Lung	RERFLCAD2	9.8
Lung	RERFLCAI	10.8
Lung	RERFLCKJ	10.1
Lung	RERFLCMS	10.3
Lung	RERFLCSQ1	10.4
Lung	SBC5	10.7
Lung	SCLC21H	10.6
Lung	SHP77	10.3
Lung	SKLU1	9.9
Lung	SKMES1	9.5
Lung	SQ1	10.6
Lung	SW1271	10.5
Lung	SW1573	10.2
Lung	SW900	10.6
Lung	VMRCLCD	10.9
Lung	VMRCLCP	11.2
Oesophagus	COLO680N	10.2
Oesophagus	ECGI10	10.4
Oesophagus	KYSE140	11
Oesophagus	KYSE150	10.4
Oesophagus	KYSE180	11.3
Oesophagus	KYSE270	10.2
Oesophagus	KYSE30	9.9
Oesophagus	KYSE410	10.2
Oesophagus	KYSE450	10.7
Oesophagus	KYSE510	10.3
Oesophagus	KYSE520	10.7
Oesophagus	KYSE70	10.1
Oesophagus	OE19	9.7
Oesophagus	OE33	11.1
Oesophagus	TE10	10.4
Oesophagus	TE11	11
Oesophagus	TE14	10.8
Oesophagus	TE15	10.2
Oesophagus	TE1	10.4
Oesophagus	TE4	11.2
Oesophagus	TE5	10.4
Oesophagus	TE6	10.4
Oesophagus	TE8	10.4
Oesophagus	TE9	10.4
Oesophagus	TT	10
Ovary	59M	10.8
Ovary	A2780	11.2
Ovary	CAOV3	10.6
Ovary	CAOV4	10.1
Ovary	COLO704	10.9
Ovary	COV318	9.8
Ovary	COV362	11.7
Ovary	COV434	11.3
Ovary	COV504	10.5
Ovary	COV644	10.8
Ovary	EFO21	10.5
Ovary	EFO27	9.9
Ovary	ES2	11.1
Ovary	FUOV1	10.5
Ovary	HEYA8	10.6
Ovary	HS571T	9.9
Ovary	IGROV1	10.6
Ovary	JHOC5	10.7
Ovary	JHOM1	10.3
Ovary	JHOM2B	10.7
Ovary	JHOS2	10.4
Ovary	JHOS4	10.3
Ovary	KURAMOCHI	10.2
Ovary	MCAS	11.5
Ovary	NIHOVCAR3	11
Ovary	OAW28	11
Ovary	OAW42	10.6
Ovary	OC314	10.4
Ovary	OC316	10.5
Ovary	ONCODG1	10.9
Ovary	OV56	10.7
Ovary	OV7	10.4
Ovary	OV90	10.5
Ovary	OVCAR4	10.2
Ovary	OVCAR8	11.5
Ovary	OVISE	10.3
Ovary	OVK18	11.5
Ovary	OVKATE	9.9
Ovary	OVMANA	11.1
Ovary	OVSAHO	10.8
Ovary	OVTOKO	10.5
Ovary	RMGI	10.5
Ovary	RMUGS	9.6
Ovary	SKOV3	10.4
Ovary	SNU119	9.4
Ovary	SNU840	10.4
Ovary	SNU8	10.1
Ovary	TOV112D	10.4
Ovary	TOV21G	10.7
Ovary	TYKNU	10.5
Pancreas	ASPC1	10.6
Pancreas	BXPC3	11.1
Pancreas	CAPAN1	10.2
Pancreas	CAPAN2	10.6
Pancreas	CFPAC1	10.7
Pancreas	DANG	11
Pancreas	HPAC	10.7
Pancreas	HPAFII	10.8
Pancreas	HS766T	10.5
Pancreas	HUPT3	9.7
Pancreas	HUPT4	10.6
Pancreas	KCIMOH1	10.4
Pancreas	KLM1	10.5
Pancreas	KP2	10.8
Pancreas	KP3	10.5
Pancreas	KP4	11.1
Pancreas	L33	10.4
Pancreas	MIAPACA2	10.8
Pancreas	PANC0203	10.3
Pancreas	PANC0213	9.5
Pancreas	PANC0327	10.9
Pancreas	PANC0403	10.8
Pancreas	PANC0504	10.1
Pancreas	PANC0813	10.5
Pancreas	PANC1005	10.6
Pancreas	PANC1	10.8
Pancreas	PATU8902	10.7
Pancreas	PATU8988S	10.1
Pancreas	PATU8988T	10.9
Pancreas	PK1	10.6
Pancreas	PK45H	11.1
Pancreas	PK59	10.7
Pancreas	PL45	10.7
Pancreas	PSN1	11.1
Pancreas	QGP1	10.5
Pancreas	SNU213	10.7
Pancreas	SNU324	10.9
Pancreas	SNU410	10.3
Pancreas	SU8686	10.2
Pancreas	SUIT2	11.1
Pancreas	SW1990	10.5
Pancreas	T3M4	10.1
Pancreas	TCCPAN2	10.3
Pancreas	YAPC	10.8
Pleura	ACCMESO1	10.4
Pleura	DM3	10.2
Pleura	ISTMES1	10.4
Pleura	ISTMES2	10.5
Pleura	JL1	10.9
Pleura	MPP89	10.3
Pleura	MSTO211H	10
Pleura	NCIH2052	10.9
Pleura	NCIH2452	10.9
Pleura	NCIH28	10.5
Prostate	22RV1	10.3
Prostate	DU145	10.9
Prostate	LNCAPCLONEFGC	10.5
Prostate	MDAPCA2B	10.1
Prostate	NCIH660	10
Prostate	PC3	9.5
Prostate	VCAP	10
Salivary gland	A253	11.2
Salivary gland	YD15	10.6
Skin	A101D	10.1
Skin	A2058	10.5
Skin	A375	10.6
Skin	C32	10.3
Skin	CHL1	10.8
Skin	CJM	11.1
Skin	COLO679	10.7
Skin	COLO741	9.7
Skin	COLO783	10
Skin	COLO792	10
Skin	COLO800	10.2
Skin	COLO818	10.1
Skin	COLO829	8.8
Skin	COLO849	9.5
Skin	G361	10.3
Skin	GRM	10.9
Skin	HMCB	11.1
Skin	HS294T	9.5
Skin	HS600T	10
Skin	HS688AT	10
Skin	HS695T	9.7
Skin	HS839T	10.1
Skin	HS852T	10.6
Skin	HS895T	9.8
Skin	HS934T	10.2
Skin	HS936T	9.9
Skin	HS939T	9.7
Skin	HS940T	9.8
Skin	HS944T	10.3
Skin	HT144	10
Skin	IGR1	11.1
Skin	IGR37	10.5
Skin	IGR39	10.7
Skin	IPC298	10.4
Skin	K029AX	9.7
Skin	LOXIMVI	10.4
Skin	MALME3M	9.8
Skin	MDAMB435S	10.6
Skin	MELHO	9.9
Skin	MELJUSO	10.4
Skin	MEWO	11.3
Skin	RPMI7951	10.7
Skin	RVH421	9.6
Skin	SH4	10.5
Skin	SKMEL1	10
Skin	SKMEL24	10.3
Skin	SKMEL28	10
Skin	SKMEL2	10.1
Skin	SKMEL30	10.9
Skin	SKMEL31	9.6
Skin	SKMEL3	9.6
Skin	SKMEL5	9.5
Skin	UACC257	9.9
Skin	UACC62	10
Skin	WM115	9.7
Skin	WM1799	10.5
Skin	WM2664	9.9
Skin	WM793	10.4
Skin	WM88	10.4
Skin	WM983B	11.2
Small intestine	HUTU80	10.8
Soft tissue	A204	10.7
Soft tissue	G401	11
Soft tissue	G402	10.7
Soft tissue	GCT	10.6
Soft tissue	HS729	10.7
Soft tissue	HT1080	10.4
Soft tissue	KYM1	10.8
Soft tissue	MESSA	10.9
Soft tissue	RD	10.7
Soft tissue	RH30	11.2
Soft tissue	RH41	11.2
Soft tissue	RKN	10.4
Soft tissue	S117	11.1
Soft tissue	SJRH30	10.8
Soft tissue	SKLMS1	10.3
Soft tissue	SKUT1	10.6
Soft tissue	TE125T	10
Soft tissue	TE159T	9.7
Soft tissue	TE441T	10.8
Soft tissue	TE617T	10.4
Stomach	2313287	10.7
Stomach	AGS	10.6
Stomach	AZ521	11
Stomach	ECC10	10.7
Stomach	ECC12	10.8
Stomach	FU97	10.5
Stomach	GCIY	10.8
Stomach	GSS	11.1
Stomach	GSU	10.6
Stomach	HGC27	10.4
Stomach	HS746T	11.3
Stomach	HUG1N	11.1
Stomach	IM95	9.9
Stomach	KATOIII	10.6
Stomach	KE39	9.9
Stomach	LMSU	10.5
Stomach	MKN1	9.8
Stomach	MKN45	11.1
Stomach	MKN74	11.6
Stomach	MKN7	10.3
Stomach	NCCSTCK140	9.9
Stomach	NCIN87	10.4
Stomach	NUGC2	10.8
Stomach	NUGC3	10.1
Stomach	NUGC4	9.9
Stomach	OCUM1	10.2
Stomach	RERFGC1B	10.1
Stomach	SH10TC	10.3
Stomach	SNU16	9.9
Stomach	SNU1	12.2
Stomach	SNU216	10.2
Stomach	SNU520	10.8
Stomach	SNU5	10.4
Stomach	SNU601	10.4
Stomach	SNU620	10.4
Stomach	SNU668	10.8
Stomach	SNU719	10.2
Stomach	TGBC11TKB	11.1
Thyroid	8305C	10.4
Thyroid	8505C	10.5
Thyroid	BCPAP	10
Thyroid	BHT101	10.4
Thyroid	CAL62	11
Thyroid	CGTHW1	11
Thyroid	FTC133	10.5
Thyroid	FTC238	11
Thyroid	ML1	10.8
Thyroid	SW579	10.4
Thyroid	TT2609C02	11.5
Thyroid	TT	9.6
Upper aerodigestive tract	BHY	10.2
Upper aerodigestive tract	BICR16	10.4
Upper aerodigestive tract	BICR18	10.2
Upper aerodigestive tract	BICR22	10.6
Upper aerodigestive tract	BICR31	10.7
Upper aerodigestive tract	BICR56	10.2
Upper aerodigestive tract	BICR6	10.7
Upper aerodigestive tract	CAL27	10.4
Upper aerodigestive tract	CAL33	10.5
Upper aerodigestive tract	DETROIT562	10.2
Upper aerodigestive tract	FADU	10.8
Upper aerodigestive tract	HS840T	10.2
Upper aerodigestive tract	HSC2	10
Upper aerodigestive tract	HSC3	10.6
Upper aerodigestive tract	HSC4	10.2
Upper aerodigestive tract	PECAPJ15	10
Upper aerodigestive tract	PECAPJ34CLONEC12	11.3
Upper aerodigestive tract	PECAPJ41CLONED2	10.8
Upper aerodigestive tract	PECAPJ49	10.9
Upper aerodigestive tract	SCC15	10.9
Upper aerodigestive tract	SCC25	10.6
Upper aerodigestive tract	SCC4	10.6
Upper aerodigestive tract	SCC9	10.4
Upper aerodigestive tract	SNU1076	10.3
Upper aerodigestive tract	SNU1214	11.2
Upper aerodigestive tract	SNU46	10.4
Upper aerodigestive tract	SNU899	10.7
Upper aerodigestive tract	YD10B	10.8
Upper aerodigestive tract	YD38	10.6
Upper aerodigestive tract	YD8	10.2
Urinary tract	5637	9.7
Urinary tract	639V	10.6
Urinary tract	647V	10.7
Urinary tract	BC3C	10.6
Urinary tract	BFTC905	11
Urinary tract	CAL29	10.7
Urinary tract	HS172T	10
Urinary tract	HT1197	10.9
Urinary tract	HT1376	9.9
Urinary tract	J82	10.1
Urinary tract	JMSU1	10.8
Urinary tract	KMBC2	9.8
Urinary tract	KU1919	10.5
Urinary tract	RT11284	10.9
Urinary tract	RT112	10.6
Urinary tract	RT4	10.2
Urinary tract	SCABER	10.2
Urinary tract	SW1710	10.7
Urinary tract	SW780	9.5
Urinary tract	T24	10.5
Urinary tract	TCCSUP	10.5
Urinary tract	UMUC1	10.1
Urinary tract	UMUC3	10.3
Urinary tract	VMCUB1	10.3

> The Human Protein Atlas (HPA)

Tissue	Expression Level (TPM)
Adipose tissue	16.1
Adrenal gland	15.9
Appendix	21.1
Bone marrow	20.3
Breast	14.3
Cerebral cortex	16.6
Cervix, uterine	18.9
Colon	11.4
Duodenum	10.3
Endometrium	23
Epididymis	10.5
Esophagus	15.5
Fallopian tube	16.1
Gallbladder	18.6
Heart muscle	7.6
Kidney	14.2
Liver	7.7
Lung	17.2
Lymph node	19.9
Ovary	16
Pancreas	1.8
Parathyroid gland	19.3
Placenta	26.1
Prostate	15.8
Rectum	12.5
Salivary gland	4.1
Seminal vesicle	14.2
Skeletal muscle	8.3
Skin	10.9
Small intestine	12.7
Smooth muscle	21.1
Spleen	20.8
Stomach	10.5
Testis	24.5
Thyroid gland	20.3
Tonsil	17.5
Urinary bladder	16.1

> Text Mining based Expression [ TOP ]
There is no record.

Summary
Symbol	SMNDC1
Name	survival motor neuron domain containing 1
Aliases	SPF30; SMNR; TDRD16C; splicing factor 30, survival of motor neuron-related; tudor domain containing 16C; 30 ......
Location	10q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.486	2.22e-25	41.8	50.5	7.7	Loss
BRCA	Breast invasive carcinoma	1075	0.386	1.86e-39	30.7	61.1	8.2	Neutral
CESC	Cervical and endocervical cancers	292	0.496	1.66e-19	30.1	63.7	6.2	Neutral
COAD	Colon adenocarcinoma	449	0.256	3.59e-08	22.9	73.3	3.8	Neutral
ESCA	Esophageal carcinoma	183	0.406	1.14e-08	32.8	53	14.2	Neutral
GBM	Glioblastoma multiforme	147	0.48	7.67e-10	91.2	8.8	0	Loss
HNSC	Head and Neck squamous cell carcinoma	514	0.445	2.25e-26	23.9	68.7	7.4	Neutral
KIRC	Kidney renal clear cell carcinoma	525	0.337	2.25e-15	18.1	79.8	2.1	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	0.253	1.44e-05	6.6	91	2.4	Neutral
LAML	Acute Myeloid Leukemia	166	0.118	0.129	0.6	97.6	1.8	Neutral
LGG	Brain Lower Grade Glioma	513	0.448	1.21e-26	24.4	75.2	0.4	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.463	8.77e-21	26.4	63.5	10.2	Neutral
LUAD	Lung adenocarcinoma	512	0.461	2.32e-28	28.1	56.2	15.6	Neutral
LUSC	Lung squamous cell carcinoma	498	0.522	3.32e-36	51.6	39.2	9.2	Loss
OV	Ovarian serous cystadenocarcinoma	300	0.586	4.46e-29	37.7	41.7	20.7	Loss
PAAD	Pancreatic adenocarcinoma	177	0.353	1.45e-06	17.5	74.6	7.9	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	0.235	0.00263	1.9	90.7	7.4	Neutral
PRAD	Prostate adenocarcinoma	491	0.289	7.12e-11	13.2	84.9	1.8	Neutral
READ	Rectum adenocarcinoma	164	0.233	0.00268	29.3	68.9	1.8	Neutral
SARC	Sarcoma	255	0.463	6.13e-15	46.7	45.5	7.8	Loss
SKCM	Skin Cutaneous Melanoma	367	0.548	3.85e-30	61.6	36	2.5	Loss
STAD	Stomach adenocarcinoma	413	0.411	2.67e-18	21.1	63.4	15.5	Neutral
TGCT	Testicular Germ Cell Tumors	150	0.348	1.26e-05	44	46	10	Loss
THCA	Thyroid carcinoma	497	0.206	3.64e-06	1.6	98	0.4	Neutral
THYM	Thymoma	119	0.271	0.0029	3.4	95	1.7	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.293	4.52e-12	11.9	67.4	20.7	Neutral

Summary
Symbol	SMNDC1
Name	survival motor neuron domain containing 1
Aliases	SPF30; SMNR; TDRD16C; splicing factor 30, survival of motor neuron-related; tudor domain containing 16C; 30 ......
Location	10q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.145	0.00268	17	408	0.002	0.0702	NS/NA
BRCA	Breast invasive carcinoma	-0.153	6.47e-06	83	785	-0.002	0.352	NS/NA
CESC	Cervical and endocervical cancers	-0.096	0.0925	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.119	0.0351	19	297	0.002	3.4e-05	NS/NA
ESCA	Esophageal carcinoma	-0.204	0.00433	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.165	0.188	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.196	4.34e-06	20	522	0.002	0.00519	NS/NA
KIRC	Kidney renal clear cell carcinoma	-0.063	0.241	24	319	0.001	0.783	NS/NA
KIRP	Kidney renal papillary cell carcinoma	-0.148	0.0106	23	275	-0.001	0.389	NS/NA
LAML	Acute Myeloid Leukemia	-0.09	0.241	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	-0.155	0.000336	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.135	0.00591	41	373	0.002	0.0108	NS/NA
LUAD	Lung adenocarcinoma	-0.169	0.000207	21	456	0.006	0.00659	NS/NA
LUSC	Lung squamous cell carcinoma	-0.143	0.00544	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	-0.45	0.23	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.038	0.611	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.165	0.0241	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.087	0.0439	35	498	0.004	3.54e-11	NS/NA
READ	Rectum adenocarcinoma	-0.334	0.000697	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.172	0.00523	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.246	6.51e-08	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.199	0.000117	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.277	0.000476	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.04	0.341	50	509	-0.007	0.445	NS/NA
THYM	Thymoma	-0.198	0.029	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.151	0.00107	34	431	-0.002	0.0297	NS/NA

Summary
Symbol	SMNDC1
Name	survival motor neuron domain containing 1
Aliases	SPF30; SMNR; TDRD16C; splicing factor 30, survival of motor neuron-related; tudor domain containing 16C; 30 ......
Location	10q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA) [ TOP ]
There is no antibody staining data.

Summary
Symbol	SMNDC1
Name	survival motor neuron domain containing 1
Aliases	SPF30; SMNR; TDRD16C; splicing factor 30, survival of motor neuron-related; tudor domain containing 16C; 30 ......
Location	10q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.77	NS	24476821
BRCA	Breast invasive carcinoma	521	1.92e-21	Significant	23000897
COAD	Colon adenocarcinoma	149	0.012	Significant	22810696
GBM	Glioblastoma multiforme	157	0.00124	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	1.48e-08	Significant	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.000945	Significant	26536169
LGG	Brain Lower Grade Glioma	513	8.69e-30	Significant	26824661
LUAD	Lung adenocarcinoma	230	2.1e-13	Significant	25079552
LUSC	Lung squamous cell carcinoma	178	0.00588	Significant	22960745
OV	Ovarian serous cystadenocarcinoma	287	0.000792	Significant	21720365
PRAD	Prostate adenocarcinoma	333	0.000371	Significant	26544944
READ	Rectum adenocarcinoma	67	0.611	NS	22810696
SKCM	Skin Cutaneous Melanoma	315	3.93e-08	Significant	26091043
STAD	Stomach adenocarcinoma	277	7.28e-10	Significant	25079317
THCA	Thyroid carcinoma	391	0.0271	Significant	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	0.0392	Significant	23636398

> Overall survival

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	0.974	0.9	NS
BRCA	Breast invasive carcinoma	1079	1.428	0.141	NS
CESC	Cervical and endocervical cancers	291	0.954	0.885	NS
COAD	Colon adenocarcinoma	439	1.143	0.637	NS
ESCA	Esophageal carcinoma	184	1.474	0.237	NS
GBM	Glioblastoma multiforme	158	0.685	0.141	NS
HNSC	Head and Neck squamous cell carcinoma	518	1.665	0.0117	Shorter
KIRC	Kidney renal clear cell carcinoma	531	1.076	0.727	NS
KIRP	Kidney renal papillary cell carcinoma	287	3.175	0.00526	Shorter
LAML	Acute Myeloid Leukemia	149	1.21	0.518	NS
LGG	Brain Lower Grade Glioma	511	0.566	0.018	Longer
LIHC	Liver hepatocellular carcinoma	365	2.085	0.00326	Shorter
LUAD	Lung adenocarcinoma	502	1.938	0.00228	Shorter
LUSC	Lung squamous cell carcinoma	494	0.912	0.647	NS
OV	Ovarian serous cystadenocarcinoma	303	0.994	0.978	NS
PAAD	Pancreatic adenocarcinoma	177	2.108	0.00486	Shorter
PCPG	Pheochromocytoma and Paraganglioma	179	594299980.432	0.317	NS
PRAD	Prostate adenocarcinoma	497	4.378	0.0566	NS
READ	Rectum adenocarcinoma	159	1.884	0.252	NS
SARC	Sarcoma	259	0.955	0.882	NS
SKCM	Skin Cutaneous Melanoma	459	0.942	0.758	NS
STAD	Stomach adenocarcinoma	388	0.859	0.506	NS
TGCT	Testicular Germ Cell Tumors	134	0	0.283	NS
THCA	Thyroid carcinoma	500	1.42	0.585	NS
THYM	Thymoma	119	0.515	0.581	NS
UCEC	Uterine Corpus Endometrial Carcinoma	543	1.483	0.212	NS

> Stage

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	-0.007	0.887	NS
BRCA	Breast invasive carcinoma	1071	-0.051	0.0973	NS
CESC	Cervical and endocervical cancers	167	-0.117	0.133	NS
COAD	Colon adenocarcinoma	445	-0.034	0.473	NS
ESCA	Esophageal carcinoma	162	0.027	0.736	NS
HNSC	Head and Neck squamous cell carcinoma	448	0.048	0.308	NS
KIRC	Kidney renal clear cell carcinoma	531	-0.013	0.763	NS
KIRP	Kidney renal papillary cell carcinoma	260	0.24	9.46e-05	Higher
LIHC	Liver hepatocellular carcinoma	347	0.144	0.00722	Higher
LUAD	Lung adenocarcinoma	507	0.164	0.000206	Higher
LUSC	Lung squamous cell carcinoma	497	0.113	0.0119	Higher
OV	Ovarian serous cystadenocarcinoma	302	0.052	0.372	NS
PAAD	Pancreatic adenocarcinoma	176	0.086	0.254	NS
READ	Rectum adenocarcinoma	156	0.022	0.788	NS
SKCM	Skin Cutaneous Melanoma	410	-0.075	0.128	NS
STAD	Stomach adenocarcinoma	392	0.004	0.94	NS
TGCT	Testicular Germ Cell Tumors	81	0.03	0.788	NS
THCA	Thyroid carcinoma	499	-0.026	0.567	NS
UCEC	Uterine Corpus Endometrial Carcinoma	501	0.097	0.0306	Higher

> Grade

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	-0.064	0.289	NS
HNSC	Head and Neck squamous cell carcinoma	498	-0.025	0.577	NS
KIRC	Kidney renal clear cell carcinoma	525	-0.074	0.0899	NS
LGG	Brain Lower Grade Glioma	514	0.028	0.527	NS
LIHC	Liver hepatocellular carcinoma	366	0.021	0.687	NS
OV	Ovarian serous cystadenocarcinoma	296	0.016	0.779	NS
PAAD	Pancreatic adenocarcinoma	176	0.125	0.098	NS
STAD	Stomach adenocarcinoma	406	-0.097	0.0506	NS
UCEC	Uterine Corpus Endometrial Carcinoma	534	0.256	2.07e-09	Higher

Summary
Symbol	SMNDC1
Name	survival motor neuron domain containing 1
Aliases	SPF30; SMNR; TDRD16C; splicing factor 30, survival of motor neuron-related; tudor domain containing 16C; 30 ......
Location	10q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	SMNDC1
Name	survival motor neuron domain containing 1
Aliases	SPF30; SMNR; TDRD16C; splicing factor 30, survival of motor neuron-related; tudor domain containing 16C; 30 ......
Location	10q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for SMNDC1.

Summary
Symbol	SMNDC1
Name	survival motor neuron domain containing 1
Aliases	SPF30; SMNR; TDRD16C; splicing factor 30, survival of motor neuron-related; tudor domain containing 16C; 30 ......
Location	10q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining [ TOP ]
There is no record for SMNDC1.