CR2Cancer

Summary
Symbol	SMYD1
Name	SET and MYND domain containing 1
Aliases	ZMYND22; KMT3D; ZMYND18; CD8 beta opposite; SET and MYND domain-containing protein 1; zinc finger, MYND doma ......
Location	2p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

[ TOP ]

Domain

PF00856 SET domain
PF01753 MYND finger

Function

Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.

Classification

Class	Modification	Substrate	Product	PubMed
Histone modification write	Histone methylation	H3K4	H3K4me	22498752

> Gene Ontology [ TOP ]
Biological Process	GO:0006338 chromatin remodeling GO:0006479 protein methylation GO:0007507 heart development GO:0007517 muscle organ development GO:0007519 skeletal muscle tissue development GO:0008213 protein alkylation GO:0010830 regulation of myotube differentiation GO:0010831 positive regulation of myotube differentiation GO:0014706 striated muscle tissue development GO:0014902 myotube differentiation GO:0016570 histone modification GO:0016571 histone methylation GO:0018022 peptidyl-lysine methylation GO:0018205 peptidyl-lysine modification GO:0032259 methylation GO:0034968 histone lysine methylation GO:0035914 skeletal muscle cell differentiation GO:0042692 muscle cell differentiation GO:0043414 macromolecule methylation GO:0045445 myoblast differentiation GO:0045661 regulation of myoblast differentiation GO:0045663 positive regulation of myoblast differentiation GO:0051146 striated muscle cell differentiation GO:0051147 regulation of muscle cell differentiation GO:0051149 positive regulation of muscle cell differentiation GO:0051153 regulation of striated muscle cell differentiation GO:0051155 positive regulation of striated muscle cell differentiation GO:0060537 muscle tissue development GO:0060538 skeletal muscle organ development
Molecular Function	GO:0003714 transcription corepressor activity GO:0008168 methyltransferase activity GO:0008170 N-methyltransferase activity GO:0008276 protein methyltransferase activity GO:0008757 S-adenosylmethionine-dependent methyltransferase activity GO:0016278 lysine N-methyltransferase activity GO:0016279 protein-lysine N-methyltransferase activity GO:0016741 transferase activity, transferring one-carbon groups GO:0018024 histone-lysine N-methyltransferase activity GO:0042054 histone methyltransferase activity
Cellular Component	-

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	-

Summary
Symbol	SMYD1
Name	SET and MYND domain containing 1
Aliases	ZMYND22; KMT3D; ZMYND18; CD8 beta opposite; SET and MYND domain-containing protein 1; zinc finger, MYND doma ......
Location	2p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM5719630	c.1333G>A	p.E445K	Substitution - Missense	Skin
COSM247481	c.1054C>T	p.R352W	Substitution - Missense	Prostate
COSM4420895	c.1146-6C>T	p.?	Unknown	Prostate
COSM5745921	c.478C>T	p.P160S	Substitution - Missense	Pancreas
COSM1409880	c.486C>G	p.S162R	Substitution - Missense	Large_intestine
COSM2823479	c.1430C>A	p.P477H	Substitution - Missense	Lung
COSM3583875	c.1296C>T	p.P432P	Substitution - coding silent	Skin
COSM4606764	c.1201C>A	p.L401M	Substitution - Missense	Adrenal_gland
COSM419075	c.341T>G	p.V114G	Substitution - Missense	Upper_aerodigestive_tract
COSM4843518	c.39C>T	p.T13T	Substitution - coding silent	Cervix
COSM341330	c.996C>A	p.C332*	Substitution - Nonsense	Lung
COSM4096165	c.1137C>G	p.D379E	Substitution - Missense	Stomach
COSM3963203	c.933T>A	p.D311E	Substitution - Missense	Lung
COSM3583861	c.306G>A	p.E102E	Substitution - coding silent	Skin
COSM5600534	c.290G>A	p.G97E	Substitution - Missense	Skin
COSM4096162	c.314+1G>C	p.?	Unknown	Stomach
COSM4458446	c.1085C>T	p.S362F	Substitution - Missense	Skin
COSM5426429	c.1215T>C	p.H405H	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM5416556	c.1280A>G	p.H427R	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM419075	c.341T>G	p.V114G	Substitution - Missense	Upper_aerodigestive_tract
COSM5680135	c.627G>T	p.W209C	Substitution - Missense	Soft_tissue
COSM2823446	c.241G>A	p.D81N	Substitution - Missense	Large_intestine
COSM1177418	c.99C>T	p.I33I	Substitution - coding silent	Large_intestine
COSM3583870	c.939G>A	p.L313L	Substitution - coding silent	Skin
COSM212053	c.827G>A	p.C276Y	Substitution - Missense	Breast
COSM419075	c.341T>G	p.V114G	Substitution - Missense	Upper_aerodigestive_tract
COSM419075	c.341T>G	p.V114G	Substitution - Missense	Skin
COSM4096167	c.1386C>T	p.R462R	Substitution - coding silent	Stomach
COSM5447519	c.138-7T>G	p.?	Unknown	Large_intestine
COSM5484572	c.1455G>A	p.L485L	Substitution - coding silent	Large_intestine
COSM443343	c.729_731delAGA	p.E244delE	Deletion - In frame	Breast
COSM4638591	c.1347C>T	p.R449R	Substitution - coding silent	Large_intestine
COSM3733531	c.709C>T	p.R237W	Substitution - Missense	Pancreas
COSM1023554	c.958C>T	p.R320C	Substitution - Missense	Stomach
COSM5771794	c.126G>C	p.V42V	Substitution - coding silent	Breast
COSM1720506	c.370_371GG>AA	p.G124N	Substitution - Missense	Skin
COSM2823477	c.1385G>A	p.R462H	Substitution - Missense	Oesophagus
COSM3939226	c.281A>G	p.K94R	Substitution - Missense	Oesophagus
COSM5638222	c.1269C>A	p.L423L	Substitution - coding silent	Oesophagus
COSM255972	c.998G>A	p.R333Q	Substitution - Missense	Central_nervous_system
COSM1752710	c.153G>A	p.V51V	Substitution - coding silent	Urinary_tract
COSM5823964	c.63G>T	p.L21L	Substitution - coding silent	Liver
COSM3758407	c.1185C>T	p.A395A	Substitution - coding silent	Large_intestine
COSM5600534	c.290G>A	p.G97E	Substitution - Missense	Skin
COSM5938952	c.853G>A	p.D285N	Substitution - Missense	Skin
COSM5471625	c.959G>A	p.R320H	Substitution - Missense	Large_intestine
COSM3583870	c.939G>A	p.L313L	Substitution - coding silent	Skin
COSM4096166	c.1386C>A	p.R462R	Substitution - coding silent	Stomach
COSM4728606	c.783A>G	p.E261E	Substitution - coding silent	Large_intestine
COSM3583873	c.1073C>T	p.S358L	Substitution - Missense	Stomach
COSM722952	c.879C>G	p.D293E	Substitution - Missense	Lung
COSM5344272	c.1362C>T	p.N454N	Substitution - coding silent	Large_intestine
COSM1023556	c.1055G>A	p.R352Q	Substitution - Missense	Endometrium
COSM1023554	c.958C>T	p.R320C	Substitution - Missense	Skin
COSM5660557	c.443delG	p.V149fs*28	Deletion - Frameshift	Soft_tissue
COSM1690769	c.910G>A	p.E304K	Substitution - Missense	Skin
COSM4728605	c.343_344delGA	p.E117fs*61	Deletion - Frameshift	Large_intestine
COSM1615193	c.335G>A	p.W112*	Substitution - Nonsense	Large_intestine
COSM1409879	c.321G>A	p.A107A	Substitution - coding silent	Large_intestine
COSM722949	c.1193G>C	p.R398P	Substitution - Missense	Lung
COSM4428446	c.406G>C	p.V136L	Substitution - Missense	Oesophagus
COSM419075	c.341T>G	p.V114G	Substitution - Missense	Upper_aerodigestive_tract
COSM3583874	c.1286C>T	p.P429L	Substitution - Missense	Skin
COSM126337	c.418G>T	p.G140W	Substitution - Missense	Upper_aerodigestive_tract
COSM1266317	c.480G>A	p.P160P	Substitution - coding silent	Stomach
COSM3583871	c.987G>A	p.V329V	Substitution - coding silent	Skin
COSM255972	c.998G>A	p.R333Q	Substitution - Missense	Central_nervous_system
COSM3583870	c.939G>A	p.L313L	Substitution - coding silent	Skin
COSM285227	c.1098C>A	p.A366A	Substitution - coding silent	Urinary_tract
COSM1266318	c.753C>T	p.S251S	Substitution - coding silent	Oesophagus
COSM4597310	c.344A>G	p.E115G	Substitution - Missense	Upper_aerodigestive_tract
COSM2823463	c.797T>A	p.L266Q	Substitution - Missense	Lung
COSM3583862	c.342G>A	p.V114V	Substitution - coding silent	Skin
COSM4526216	c.1380G>A	p.K460K	Substitution - coding silent	Skin
COSM4922802	c.139C>T	p.L47F	Substitution - Missense	Liver
COSM126336	c.235C>A	p.Q79K	Substitution - Missense	Upper_aerodigestive_tract
COSM3720644	c.274G>T	p.A92S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3583860	c.291G>A	p.G97G	Substitution - coding silent	Skin
COSM1729929	c.785G>C	p.R262P	Substitution - Missense	Liver
COSM1752710	c.153G>A	p.V51V	Substitution - coding silent	Urinary_tract
COSM5471626	c.1355G>A	p.R452H	Substitution - Missense	Large_intestine
COSM3583866	c.678C>T	p.S226S	Substitution - coding silent	Skin
COSM6010210	c.409G>C	p.E137Q	Substitution - Missense	Skin
COSM5823727	c.977A>T	p.H326L	Substitution - Missense	Liver
COSM1409883	c.1184C>T	p.A395V	Substitution - Missense	Large_intestine
COSM5566138	c.1384C>T	p.R462C	Substitution - Missense	Prostate
COSM1288107	c.668C>A	p.A223E	Substitution - Missense	Autonomic_ganglia
COSM5891708	c.403C>T	p.H135Y	Substitution - Missense	Skin
COSM5566138	c.1384C>T	p.R462C	Substitution - Missense	Prostate
COSM3414388	c.137+4T>C	p.?	Unknown	Oesophagus
COSM3583868	c.888G>A	p.K296K	Substitution - coding silent	Skin
COSM419075	c.341T>G	p.V114G	Substitution - Missense	Upper_aerodigestive_tract
COSM3840206	c.628C>T	p.P210S	Substitution - Missense	Breast
COSM1409884	c.1344A>G	p.L448L	Substitution - coding silent	Large_intestine
COSM1690771	c.1240G>A	p.G414R	Substitution - Missense	Skin
COSM4728607	c.1345C>T	p.R449C	Substitution - Missense	Large_intestine
COSM419074	c.1322G>A	p.R441Q	Substitution - Missense	Urinary_tract
COSM1266315	c.427G>A	p.E143K	Substitution - Missense	Oesophagus
COSM3702248	c.288T>C	p.Y96Y	Substitution - coding silent	Liver
COSM387053	c.576C>T	p.A192A	Substitution - coding silent	Lung
COSM1720506	c.370_371GG>AA	p.G124N	Substitution - Missense	Skin
COSM1023549	c.227G>A	p.R76H	Substitution - Missense	Large_intestine
COSM3840205	c.96C>T	p.I32I	Substitution - coding silent	Breast
COSM419075	c.341T>G	p.V114G	Substitution - Missense	Urinary_tract
COSM5719630	c.1333G>A	p.E445K	Substitution - Missense	Skin
COSM4934954	c.849G>C	p.L283L	Substitution - coding silent	Liver
COSM5425746	c.795G>A	p.Q265Q	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM5736120	c.1457T>C	p.F486S	Substitution - Missense	Small_intestine
COSM5680136	c.1282G>A	p.G428R	Substitution - Missense	Soft_tissue
COSM5993875	c.844A>C	p.K282Q	Substitution - Missense	Prostate
COSM5951082	c.1314+2C>T	p.?	Unknown	Oesophagus
COSM2823445	c.120C>T	p.S40S	Substitution - coding silent	Skin
COSM3972386	c.678C>G	p.S226S	Substitution - coding silent	Central_nervous_system
COSM23312	c.779_795del17	p.E260fs*8	Deletion - Frameshift	Lung
COSM5993875	c.844A>C	p.K282Q	Substitution - Missense	Prostate
COSM379920	c.888G>T	p.K296N	Substitution - Missense	Lung
COSM419075	c.341T>G	p.V114G	Substitution - Missense	Upper_aerodigestive_tract
COSM5719630	c.1333G>A	p.E445K	Substitution - Missense	Skin
COSM3910746	c.454G>A	p.D152N	Substitution - Missense	Skin
COSM4540487	c.284G>A	p.R95K	Substitution - Missense	Skin
COSM247482	c.390C>T	p.D130D	Substitution - coding silent	Prostate
COSM1409885	c.1424C>T	p.A475V	Substitution - Missense	Large_intestine
COSM1023558	c.1146-1G>T	p.?	Unknown	Endometrium
COSM1615193	c.335G>A	p.W112*	Substitution - Nonsense	Liver
COSM5699856	c.1154A>G	p.Y385C	Substitution - Missense	Soft_tissue
COSM443344	c.1441C>G	p.P481A	Substitution - Missense	Breast
COSM164494	c.1074G>A	p.S358S	Substitution - coding silent	Breast
COSM3963201	c.479C>A	p.P160Q	Substitution - Missense	Lung
COSM443342	c.552C>T	p.L184L	Substitution - coding silent	Breast
COSM1690770	c.1022C>T	p.P341L	Substitution - Missense	Skin
COSM285227	c.1098C>A	p.A366A	Substitution - coding silent	Large_intestine
COSM373626	c.550C>G	p.L184V	Substitution - Missense	Lung
COSM5566138	c.1384C>T	p.R462C	Substitution - Missense	Prostate
COSM443340	c.337C>A	p.R113R	Substitution - coding silent	Thyroid
COSM3583859	c.182A>G	p.K61R	Substitution - Missense	Skin
COSM1690773	c.1294C>T	p.P432S	Substitution - Missense	Skin
COSM3583863	c.475C>T	p.P159S	Substitution - Missense	Skin
COSM5439931	c.1086C>A	p.S362S	Substitution - coding silent	Oesophagus
COSM5719629	c.1242G>A	p.G414G	Substitution - coding silent	Skin
COSM443340	c.337C>A	p.R113R	Substitution - coding silent	Thyroid
COSM5397553	c.1055_1056GG>AA	p.R352Q	Substitution - Missense	Skin
COSM443340	c.337C>A	p.R113R	Substitution - coding silent	Upper_aerodigestive_tract
COSM76534	c.320C>T	p.A107V	Substitution - Missense	Ovary
COSM5600534	c.290G>A	p.G97E	Substitution - Missense	Skin
COSM379218	c.583G>A	p.V195I	Substitution - Missense	Lung
COSM1177418	c.99C>T	p.I33I	Substitution - coding silent	Endometrium
COSM4597310	c.344A>G	p.E115G	Substitution - Missense	Upper_aerodigestive_tract
COSM5719630	c.1333G>A	p.E445K	Substitution - Missense	Skin
COSM4612922	c.128delT	p.F44fs*41	Deletion - Frameshift	Large_intestine
COSM5973920	c.201G>A	p.Q67Q	Substitution - coding silent	Upper_aerodigestive_tract
COSM81746	c.186C>G	p.L62L	Substitution - coding silent	Ovary
COSM107979	c.898G>A	p.E300K	Substitution - Missense	Skin
COSM1023545	c.24C>T	p.N8N	Substitution - coding silent	Endometrium
COSM5425746	c.795G>A	p.Q265Q	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM1690769	c.910G>A	p.E304K	Substitution - Missense	Urinary_tract
COSM5973919	c.59G>T	p.G20V	Substitution - Missense	Upper_aerodigestive_tract
COSM4096164	c.632A>G	p.N211S	Substitution - Missense	Stomach
COSM4758546	c.541G>A	p.G181S	Substitution - Missense	Stomach
COSM401988	c.995G>T	p.C332F	Substitution - Missense	Lung
COSM225998	c.859C>T	p.L287F	Substitution - Missense	Skin
COSM5689506	c.1073C>G	p.S358W	Substitution - Missense	Soft_tissue
COSM5719629	c.1242G>A	p.G414G	Substitution - coding silent	Skin
COSM164494	c.1074G>A	p.S358S	Substitution - coding silent	Breast
COSM1023549	c.227G>A	p.R76H	Substitution - Missense	Endometrium
COSM3583864	c.600C>T	p.N200N	Substitution - coding silent	Skin
COSM1690772	c.1245G>A	p.M415I	Substitution - Missense	Skin
COSM121913	c.513G>A	p.S171S	Substitution - coding silent	Endometrium
COSM3583873	c.1073C>T	p.S358L	Substitution - Missense	Skin
COSM722951	c.895C>G	p.Q299E	Substitution - Missense	Lung
COSM3583872	c.1018G>A	p.E340K	Substitution - Missense	Skin
COSM5566138	c.1384C>T	p.R462C	Substitution - Missense	Prostate
COSM1409876	c.37A>G	p.T13A	Substitution - Missense	Large_intestine
COSM4547506	c.424G>A	p.E142K	Substitution - Missense	Skin
COSM4096163	c.620A>C	p.D207A	Substitution - Missense	Stomach
COSM1023554	c.958C>T	p.R320C	Substitution - Missense	Endometrium
COSM5397552	c.17T>A	p.M6K	Substitution - Missense	Skin
COSM419075	c.341T>G	p.V114G	Substitution - Missense	Upper_aerodigestive_tract
COSM5600534	c.290G>A	p.G97E	Substitution - Missense	Skin
COSM1023547	c.223G>A	p.D75N	Substitution - Missense	Endometrium
COSM419075	c.341T>G	p.V114G	Substitution - Missense	Upper_aerodigestive_tract
COSM5993875	c.844A>C	p.K282Q	Substitution - Missense	Prostate
COSM1685876	c.829G>A	p.E277K	Substitution - Missense	Skin
COSM5959319	c.302A>G	p.N101S	Substitution - Missense	Thyroid
COSM3583867	c.714C>T	p.A238A	Substitution - coding silent	Skin
COSM722957	c.8T>G	p.I3R	Substitution - Missense	Lung
COSM3840208	c.1411A>G	p.M471V	Substitution - Missense	Breast
COSM5579625	c.383C>A	p.S128Y	Substitution - Missense	Skin
COSM722956	c.38C>A	p.T13N	Substitution - Missense	Lung
COSM5566138	c.1384C>T	p.R462C	Substitution - Missense	Prostate
COSM5719629	c.1242G>A	p.G414G	Substitution - coding silent	Skin
COSM4833129	c.1353C>T	p.F451F	Substitution - coding silent	Cervix
COSM3910745	c.53G>A	p.G18E	Substitution - Missense	Skin
COSM5809210	c.375C>T	p.C125C	Substitution - coding silent	Liver
COSM3583876	c.1459C>T	p.H487Y	Substitution - Missense	Skin
COSM121913	c.513G>A	p.S171S	Substitution - coding silent	Upper_aerodigestive_tract
COSM4141289	c.380T>C	p.V127A	Substitution - Missense	Ovary
COSM5600534	c.290G>A	p.G97E	Substitution - Missense	Skin
COSM1690771	c.1240G>A	p.G414R	Substitution - Missense	Stomach
COSM3840207	c.771C>A	p.N257K	Substitution - Missense	Breast
COSM1565938	c.275C>G	p.A92G	Substitution - Missense	Large_intestine
COSM1226914	c.575C>T	p.A192V	Substitution - Missense	Large_intestine
COSM5719629	c.1242G>A	p.G414G	Substitution - coding silent	Skin
COSM3583869	c.926C>T	p.S309F	Substitution - Missense	Skin
COSM4910156	c.814T>A	p.F272I	Substitution - Missense	Liver
COSM1023554	c.958C>T	p.R320C	Substitution - Missense	Liver
COSM4186816	c.435G>C	p.K145N	Substitution - Missense	Kidney
COSM5928354	c.110G>A	p.R37Q	Substitution - Missense	Skin
COSM380490	c.579G>T	p.V193V	Substitution - coding silent	Lung
COSM4889661	c.174G>T	p.R58S	Substitution - Missense	Upper_aerodigestive_tract
COSM576304	c.1368C>A	p.F456L	Substitution - Missense	Large_intestine
COSM5993875	c.844A>C	p.K282Q	Substitution - Missense	Prostate
COSM4511309	c.864C>T	p.F288F	Substitution - coding silent	Skin
COSM164494	c.1074G>A	p.S358S	Substitution - coding silent	Pancreas
COSM5818260	c.708C>A	p.L236L	Substitution - coding silent	Liver
COSM4553421	c.58G>A	p.G20S	Substitution - Missense	Liver
COSM5263529	c.24C>A	p.N8K	Substitution - Missense	Soft_tissue
COSM4553421	c.58G>A	p.G20S	Substitution - Missense	Skin
COSM3972385	c.324G>A	p.A108A	Substitution - coding silent	Central_nervous_system
COSM4463418	c.1290C>T	p.S430S	Substitution - coding silent	Skin
COSM1685876	c.829G>A	p.E277K	Substitution - Missense	Skin
COSM3583865	c.633C>T	p.N211N	Substitution - coding silent	Skin
COSM1409881	c.719G>A	p.G240D	Substitution - Missense	Large_intestine
COSM3963202	c.679A>T	p.M227L	Substitution - Missense	Lung
COSM5593217	c.1241G>A	p.G414E	Substitution - Missense	Skin
COSM4807845	c.1330A>G	p.T444A	Substitution - Missense	Pancreas
COSM1615193	c.335G>A	p.W112*	Substitution - Nonsense	Liver
COSM1266316	c.1271T>C	p.L424P	Substitution - Missense	Oesophagus
COSM337113	c.1216G>A	p.A406T	Substitution - Missense	Lung
COSM366313	c.277A>T	p.I93F	Substitution - Missense	Lung
COSM1023551	c.358G>A	p.G120R	Substitution - Missense	Endometrium
COSM4133974	c.1390G>A	p.A464T	Substitution - Missense	Thyroid
COSM2823476	c.1363G>A	p.E455K	Substitution - Missense	Skin
COSM4977206	c.392A>G	p.D131G	Substitution - Missense	Oesophagus
COSM5880931	c.897G>T	p.Q299H	Substitution - Missense	Soft_tissue
COSM722954	c.868G>C	p.G290R	Substitution - Missense	Lung
COSM4597310	c.344A>G	p.E115G	Substitution - Missense	Upper_aerodigestive_tract
COSM4927103	c.1446C>T	p.S482S	Substitution - coding silent	Liver

> Text Mining based Variations [ TOP ]
There is no record for SMYD1.

Summary
Symbol	SMYD1
Name	SET and MYND domain containing 1
Aliases	ZMYND22; KMT3D; ZMYND18; CD8 beta opposite; SET and MYND domain-containing protein 1; zinc finger, MYND doma ......
Location	2p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM) [ TOP ]
There is no PTM data

Summary
Symbol	SMYD1
Name	SET and MYND domain containing 1
Aliases	ZMYND22; KMT3D; ZMYND18; CD8 beta opposite; SET and MYND domain-containing protein 1; zinc finger, MYND doma ......
Location	2p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BRCA	Breast invasive carcinoma	112	1100	4.127	-2.771	-5.891	7.36e-75	Under
COAD	Colon adenocarcinoma	41	459	0.214	-3.482	-3.076	3.25e-14	Under
ESCA	Esophageal carcinoma	11	185	-5.407	-5.477	-1.702	0.0516	NS
GBM	Glioblastoma multiforme	5	166	1.625	-2.479	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	2.776	-3.956	-3.9	3.18e-08	Under
LGG	Brain Lower Grade Glioma	0	530	NA	-2.278	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	-6.34	-6.345	-1.048	0.0184	Under
READ	Rectum adenocarcinoma	10	167	3.078	-3.335	-5.329	4.32e-12	Under
SARC	Sarcoma	2	263	-6.412	-5.783	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	-2.587	-2.415	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	-2.064	-3.431	-2.833	0.000341	Under
TGCT	Testicular Germ Cell Tumors	0	156	NA	-2.843	NA	NA	NA

> Cancer Cell Line Encyclopedia (CCLE)

[ TOP ]

Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	3.8
Autonomic ganglia	CHP212	3.8
Autonomic ganglia	IMR32	3.6
Autonomic ganglia	KELLY	3.9
Autonomic ganglia	KPNRTBM1	3.6
Autonomic ganglia	KPNSI9S	3.8
Autonomic ganglia	KPNYN	4
Autonomic ganglia	MHHNB11	3.9
Autonomic ganglia	NB1	4.2
Autonomic ganglia	NH6	3.8
Autonomic ganglia	SHSY5Y	3.7
Autonomic ganglia	SIMA	3.7
Autonomic ganglia	SKNAS	3.9
Autonomic ganglia	SKNBE2	3.8
Autonomic ganglia	SKNDZ	3.9
Autonomic ganglia	SKNFI	3.9
Autonomic ganglia	SKNSH	3.8
Biliary tract	HUCCT1	3.9
Biliary tract	HUH28	4
Biliary tract	SNU1079	3.9
Biliary tract	SNU1196	4
Biliary tract	SNU245	4.1
Biliary tract	SNU308	3.9
Biliary tract	SNU478	3.9
Bone	143B	3.6
Bone	A673	3.9
Bone	CADOES1	3.7
Bone	CAL78	3.6
Bone	G292CLONEA141B1	3.8
Bone	HOS	3.9
Bone	HS706T	3.9
Bone	HS737T	3.8
Bone	HS819T	3.6
Bone	HS821T	3.8
Bone	HS822T	3.6
Bone	HS863T	3.5
Bone	HS870T	3.9
Bone	HS888T	3.6
Bone	MG63	3.7
Bone	MHHES1	3.6
Bone	OUMS27	3.7
Bone	RDES	3.9
Bone	SJSA1	3.8
Bone	SKES1	3.8
Bone	SKNMC	3.8
Bone	SW1353	3.9
Bone	T173	4.1
Bone	TC71	4.1
Bone	U2OS	3.8
Breast	AU565	4.1
Breast	BT20	4
Breast	BT474	4
Breast	BT483	3.9
Breast	BT549	4.2
Breast	CAL120	3.6
Breast	CAL148	3.8
Breast	CAL51	3.6
Breast	CAL851	4.1
Breast	CAMA1	4
Breast	DU4475	4.4
Breast	EFM192A	3.8
Breast	EFM19	4
Breast	EVSAT	3.9
Breast	HCC1143	3.9
Breast	HCC1187	3.7
Breast	HCC1395	3.8
Breast	HCC1419	3.8
Breast	HCC1428	3.9
Breast	HCC1500	3.8
Breast	HCC1569	4
Breast	HCC1599	3.8
Breast	HCC1806	3.8
Breast	HCC1937	3.8
Breast	HCC1954	3.8
Breast	HCC202	4.1
Breast	HCC2157	4.1
Breast	HCC2218	4
Breast	HCC38	3.7
Breast	HCC70	3.9
Breast	HDQP1	3.9
Breast	HMC18	4.4
Breast	HS274T	3.9
Breast	HS281T	3.8
Breast	HS343T	3.8
Breast	HS578T	3.9
Breast	HS606T	3.8
Breast	HS739T	3.8
Breast	HS742T	3.6
Breast	JIMT1	3.6
Breast	KPL1	3.7
Breast	MCF7	3.8
Breast	MDAMB134VI	3.4
Breast	MDAMB157	3.6
Breast	MDAMB175VII	3.8
Breast	MDAMB231	3.9
Breast	MDAMB361	3.7
Breast	MDAMB415	3.8
Breast	MDAMB436	3.8
Breast	MDAMB453	3.8
Breast	MDAMB468	4
Breast	SKBR3	4
Breast	T47D	4
Breast	UACC812	3.6
Breast	UACC893	4.1
Breast	YMB1	3.9
Breast	ZR751	3.7
Breast	ZR7530	3.9
Central nervous system	1321N1	3.8
Central nervous system	42MGBA	3.7
Central nervous system	8MGBA	3.6
Central nervous system	A172	3.8
Central nervous system	AM38	3.5
Central nervous system	BECKER	3.6
Central nervous system	CAS1	4
Central nervous system	CCFSTTG1	3.9
Central nervous system	D283MED	3.8
Central nervous system	D341MED	3.9
Central nervous system	DAOY	4
Central nervous system	DBTRG05MG	3.7
Central nervous system	DKMG	3.9
Central nervous system	GAMG	3.9
Central nervous system	GB1	3.6
Central nervous system	GI1	4.2
Central nervous system	GMS10	3.8
Central nervous system	GOS3	4
Central nervous system	H4	4.1
Central nervous system	HS683	3.7
Central nervous system	KALS1	3.7
Central nervous system	KG1C	3.5
Central nervous system	KNS42	3.9
Central nervous system	KNS60	3.7
Central nervous system	KNS81	3.9
Central nervous system	KS1	3.7
Central nervous system	LN18	3.9
Central nervous system	LN229	3.8
Central nervous system	M059K	3.8
Central nervous system	MOGGCCM	3.9
Central nervous system	MOGGUVW	3.7
Central nervous system	NMCG1	3.5
Central nervous system	ONS76	3.8
Central nervous system	SF126	3.6
Central nervous system	SF295	4
Central nervous system	SNB19	3.8
Central nervous system	SNU1105	4
Central nervous system	SNU201	3.9
Central nervous system	SNU466	3.8
Central nervous system	SNU489	3.6
Central nervous system	SNU626	4
Central nervous system	SNU738	4.3
Central nervous system	SW1088	3.7
Central nervous system	SW1783	3.8
Central nervous system	T98G	3.9
Central nervous system	TM31	3.6
Central nervous system	U118MG	3.7
Central nervous system	U138MG	3.7
Central nervous system	U251MG	3.8
Central nervous system	U87MG	3.8
Central nervous system	YH13	3.4
Central nervous system	YKG1	3.6
Endometrium	AN3CA	4.1
Endometrium	COLO684	3.7
Endometrium	EFE184	3.9
Endometrium	EN	4.1
Endometrium	ESS1	3.8
Endometrium	HEC108	4.1
Endometrium	HEC151	4
Endometrium	HEC1A	3.8
Endometrium	HEC1B	3.8
Endometrium	HEC251	3.7
Endometrium	HEC265	4.4
Endometrium	HEC50B	3.8
Endometrium	HEC59	4
Endometrium	HEC6	3.8
Endometrium	ISHIKAWAHERAKLIO02ER	3.7
Endometrium	JHUEM1	3.8
Endometrium	JHUEM2	3.7
Endometrium	JHUEM3	3.4
Endometrium	KLE	3.9
Endometrium	MFE280	4.1
Endometrium	MFE296	4.2
Endometrium	MFE319	4.3
Endometrium	RL952	3.9
Endometrium	SNGM	4
Endometrium	SNU1077	3.8
Endometrium	SNU685	3.5
Endometrium	TEN	3.7
Haematopoietic and lymphoid	697	4
Haematopoietic and lymphoid	A3KAW	4.2
Haematopoietic and lymphoid	A4FUK	4.1
Haematopoietic and lymphoid	ALLSIL	4
Haematopoietic and lymphoid	AML193	4.1
Haematopoietic and lymphoid	AMO1	3.9
Haematopoietic and lymphoid	BCP1	3.8
Haematopoietic and lymphoid	BDCM	4
Haematopoietic and lymphoid	BL41	3.7
Haematopoietic and lymphoid	BL70	3.8
Haematopoietic and lymphoid	BV173	3.8
Haematopoietic and lymphoid	CA46	4.2
Haematopoietic and lymphoid	CI1	4.1
Haematopoietic and lymphoid	CMK115	3.8
Haematopoietic and lymphoid	CMK86	3.7
Haematopoietic and lymphoid	CMK	4
Haematopoietic and lymphoid	CMLT1	3.6
Haematopoietic and lymphoid	COLO775	3.9
Haematopoietic and lymphoid	DAUDI	3.9
Haematopoietic and lymphoid	DB	4
Haematopoietic and lymphoid	DEL	3.7
Haematopoietic and lymphoid	DND41	3.7
Haematopoietic and lymphoid	DOHH2	3.7
Haematopoietic and lymphoid	EB1	4.1
Haematopoietic and lymphoid	EB2	3.7
Haematopoietic and lymphoid	EHEB	3.8
Haematopoietic and lymphoid	EJM	3.9
Haematopoietic and lymphoid	EM2	3.8
Haematopoietic and lymphoid	EOL1	3.8
Haematopoietic and lymphoid	F36P	3.8
Haematopoietic and lymphoid	GA10	4.1
Haematopoietic and lymphoid	GDM1	3.8
Haematopoietic and lymphoid	GRANTA519	3.9
Haematopoietic and lymphoid	HDLM2	3.9
Haematopoietic and lymphoid	HDMYZ	3.7
Haematopoietic and lymphoid	HEL9217	4.1
Haematopoietic and lymphoid	HEL	3.7
Haematopoietic and lymphoid	HH	4.2
Haematopoietic and lymphoid	HL60	4
Haematopoietic and lymphoid	HPBALL	3.9
Haematopoietic and lymphoid	HS604T	3.9
Haematopoietic and lymphoid	HS611T	3.7
Haematopoietic and lymphoid	HS616T	3.8
Haematopoietic and lymphoid	HS751T	3.9
Haematopoietic and lymphoid	HT	4
Haematopoietic and lymphoid	HTK	3.7
Haematopoietic and lymphoid	HUNS1	3.9
Haematopoietic and lymphoid	HUT102	3.9
Haematopoietic and lymphoid	HUT78	3.8
Haematopoietic and lymphoid	JEKO1	3.7
Haematopoietic and lymphoid	JK1	3.7
Haematopoietic and lymphoid	JM1	4.1
Haematopoietic and lymphoid	JURKAT	3.7
Haematopoietic and lymphoid	JURLMK1	3.6
Haematopoietic and lymphoid	JVM2	3.8
Haematopoietic and lymphoid	JVM3	3.7
Haematopoietic and lymphoid	K562	4.3
Haematopoietic and lymphoid	KARPAS299	3.9
Haematopoietic and lymphoid	KARPAS422	3.6
Haematopoietic and lymphoid	KARPAS620	3.6
Haematopoietic and lymphoid	KASUMI1	4.1
Haematopoietic and lymphoid	KASUMI2	3.9
Haematopoietic and lymphoid	KASUMI6	4
Haematopoietic and lymphoid	KCL22	3.8
Haematopoietic and lymphoid	KE37	3.8
Haematopoietic and lymphoid	KE97	3.8
Haematopoietic and lymphoid	KG1	3.9
Haematopoietic and lymphoid	KHM1B	4.2
Haematopoietic and lymphoid	KIJK	4
Haematopoietic and lymphoid	KMH2	3.7
Haematopoietic and lymphoid	KMM1	4.1
Haematopoietic and lymphoid	KMS11	4
Haematopoietic and lymphoid	KMS12BM	4.1
Haematopoietic and lymphoid	KMS18	3.6
Haematopoietic and lymphoid	KMS20	3.8
Haematopoietic and lymphoid	KMS21BM	4
Haematopoietic and lymphoid	KMS26	3.8
Haematopoietic and lymphoid	KMS27	3.8
Haematopoietic and lymphoid	KMS28BM	3.7
Haematopoietic and lymphoid	KMS34	3.8
Haematopoietic and lymphoid	KO52	3.8
Haematopoietic and lymphoid	KOPN8	4.1
Haematopoietic and lymphoid	KU812	3.7
Haematopoietic and lymphoid	KYO1	4
Haematopoietic and lymphoid	L1236	3.9
Haematopoietic and lymphoid	L363	4
Haematopoietic and lymphoid	L428	4
Haematopoietic and lymphoid	L540	3.8
Haematopoietic and lymphoid	LAMA84	3.7
Haematopoietic and lymphoid	LOUCY	3.7
Haematopoietic and lymphoid	LP1	3.9
Haematopoietic and lymphoid	M07E	3.8
Haematopoietic and lymphoid	MC116	4.1
Haematopoietic and lymphoid	ME1	3.8
Haematopoietic and lymphoid	MEC1	3.6
Haematopoietic and lymphoid	MEC2	3.8
Haematopoietic and lymphoid	MEG01	3.6
Haematopoietic and lymphoid	MHHCALL2	3.8
Haematopoietic and lymphoid	MHHCALL3	3.8
Haematopoietic and lymphoid	MHHCALL4	4
Haematopoietic and lymphoid	MINO	4
Haematopoietic and lymphoid	MJ	3.8
Haematopoietic and lymphoid	MM1S	3.7
Haematopoietic and lymphoid	MOLM13	4
Haematopoietic and lymphoid	MOLM16	3.8
Haematopoietic and lymphoid	MOLM6	3.6
Haematopoietic and lymphoid	MOLP2	3.7
Haematopoietic and lymphoid	MOLP8	3.7
Haematopoietic and lymphoid	MOLT13	3.8
Haematopoietic and lymphoid	MOLT16	4.2
Haematopoietic and lymphoid	MOLT4	3.7
Haematopoietic and lymphoid	MONOMAC1	3.8
Haematopoietic and lymphoid	MONOMAC6	3.6
Haematopoietic and lymphoid	MOTN1	3.8
Haematopoietic and lymphoid	MUTZ5	3.6
Haematopoietic and lymphoid	MV411	3.8
Haematopoietic and lymphoid	NALM19	3.6
Haematopoietic and lymphoid	NALM1	3.7
Haematopoietic and lymphoid	NALM6	3.7
Haematopoietic and lymphoid	NAMALWA	3.6
Haematopoietic and lymphoid	NB4	4.1
Haematopoietic and lymphoid	NCIH929	4.1
Haematopoietic and lymphoid	NCO2	3.8
Haematopoietic and lymphoid	NOMO1	3.8
Haematopoietic and lymphoid	NUDHL1	4.1
Haematopoietic and lymphoid	NUDUL1	3.9
Haematopoietic and lymphoid	OCIAML2	3.9
Haematopoietic and lymphoid	OCIAML3	3.8
Haematopoietic and lymphoid	OCIAML5	3.8
Haematopoietic and lymphoid	OCILY10	4.1
Haematopoietic and lymphoid	OCILY19	3.7
Haematopoietic and lymphoid	OCILY3	3.9
Haematopoietic and lymphoid	OCIM1	3.8
Haematopoietic and lymphoid	OPM2	3.9
Haematopoietic and lymphoid	P12ICHIKAWA	4
Haematopoietic and lymphoid	P31FUJ	3.9
Haematopoietic and lymphoid	P3HR1	4.2
Haematopoietic and lymphoid	PCM6	3.9
Haematopoietic and lymphoid	PEER	3.8
Haematopoietic and lymphoid	PF382	3.8
Haematopoietic and lymphoid	PFEIFFER	3.8
Haematopoietic and lymphoid	PL21	3.9
Haematopoietic and lymphoid	RAJI	4.1
Haematopoietic and lymphoid	RCHACV	3.7
Haematopoietic and lymphoid	REC1	3.9
Haematopoietic and lymphoid	REH	3.6
Haematopoietic and lymphoid	RI1	4.1
Haematopoietic and lymphoid	RL	4.3
Haematopoietic and lymphoid	RPMI8226	4.2
Haematopoietic and lymphoid	RPMI8402	3.9
Haematopoietic and lymphoid	RS411	4
Haematopoietic and lymphoid	SEM	4.1
Haematopoietic and lymphoid	SET2	3.9
Haematopoietic and lymphoid	SIGM5	3.8
Haematopoietic and lymphoid	SKM1	3.6
Haematopoietic and lymphoid	SKMM2	3.8
Haematopoietic and lymphoid	SR786	3.9
Haematopoietic and lymphoid	ST486	4
Haematopoietic and lymphoid	SUDHL10	3.9
Haematopoietic and lymphoid	SUDHL1	3.8
Haematopoietic and lymphoid	SUDHL4	4.3
Haematopoietic and lymphoid	SUDHL5	4.1
Haematopoietic and lymphoid	SUDHL6	3.9
Haematopoietic and lymphoid	SUDHL8	4
Haematopoietic and lymphoid	SUPB15	3.9
Haematopoietic and lymphoid	SUPHD1	3.9
Haematopoietic and lymphoid	SUPM2	3.8
Haematopoietic and lymphoid	SUPT11	3.7
Haematopoietic and lymphoid	SUPT1	4
Haematopoietic and lymphoid	TALL1	3.8
Haematopoietic and lymphoid	TF1	3.8
Haematopoietic and lymphoid	THP1	3.8
Haematopoietic and lymphoid	TO175T	4
Haematopoietic and lymphoid	TOLEDO	3.9
Haematopoietic and lymphoid	U266B1	4.1
Haematopoietic and lymphoid	U937	3.7
Haematopoietic and lymphoid	UT7	3.8
Haematopoietic and lymphoid	WSUDLCL2	3.8
Kidney	769P	3.9
Kidney	786O	3.8
Kidney	A498	4
Kidney	A704	3.7
Kidney	ACHN	3.8
Kidney	BFTC909	3.9
Kidney	CAKI1	3.6
Kidney	CAKI2	3.9
Kidney	CAL54	3.9
Kidney	KMRC1	3.9
Kidney	KMRC20	3.9
Kidney	KMRC2	3.9
Kidney	KMRC3	3.9
Kidney	OSRC2	3.6
Kidney	RCC10RGB	3.6
Kidney	SNU1272	3.8
Kidney	SNU349	3.6
Kidney	TUHR10TKB	3.6
Kidney	TUHR14TKB	3.7
Kidney	TUHR4TKB	3.7
Kidney	VMRCRCW	3.7
Kidney	VMRCRCZ	3.9
Large intestine	C2BBE1	3.9
Large intestine	CCK81	3.8
Large intestine	CL11	3.7
Large intestine	CL14	3.8
Large intestine	CL34	3.6
Large intestine	CL40	3.9
Large intestine	COLO205	3.9
Large intestine	COLO320	3.7
Large intestine	COLO678	3.6
Large intestine	CW2	3.7
Large intestine	DLD1	4
Large intestine	GP2D	3.7
Large intestine	HCC56	4
Large intestine	HCT116	3.8
Large intestine	HCT15	3.9
Large intestine	HS675T	3.8
Large intestine	HS698T	3.9
Large intestine	HT115	3.7
Large intestine	HT29	4.1
Large intestine	HT55	3.5
Large intestine	KM12	3.7
Large intestine	LOVO	3.8
Large intestine	LS1034	4.1
Large intestine	LS123	3.9
Large intestine	LS180	3.8
Large intestine	LS411N	4
Large intestine	LS513	3.8
Large intestine	MDST8	3.8
Large intestine	NCIH508	3.8
Large intestine	NCIH716	3.8
Large intestine	NCIH747	4
Large intestine	OUMS23	3.7
Large intestine	RCM1	3.8
Large intestine	RKO	3.9
Large intestine	SKCO1	3.8
Large intestine	SNU1040	3.8
Large intestine	SNU1197	3.7
Large intestine	SNU175	4.1
Large intestine	SNU283	3.7
Large intestine	SNU407	3.9
Large intestine	SNU503	3.7
Large intestine	SNU61	3.8
Large intestine	SNU81	3.6
Large intestine	SNUC1	3.8
Large intestine	SNUC2A	3.9
Large intestine	SNUC4	3.7
Large intestine	SNUC5	3.8
Large intestine	SW1116	4.1
Large intestine	SW1417	4.1
Large intestine	SW1463	4.1
Large intestine	SW403	3.9
Large intestine	SW480	3.9
Large intestine	SW48	3.7
Large intestine	SW620	4
Large intestine	SW837	3.9
Large intestine	SW948	3.7
Large intestine	T84	3.9
Liver	ALEXANDERCELLS	3.9
Liver	C3A	4
Liver	HEP3B217	3.9
Liver	HEPG2	4.1
Liver	HLE	4
Liver	HLF	3.9
Liver	HUH1	4.1
Liver	HUH6	3.8
Liver	HUH7	3.7
Liver	JHH1	4
Liver	JHH2	3.7
Liver	JHH4	3.8
Liver	JHH5	3.8
Liver	JHH6	3.9
Liver	JHH7	4
Liver	LI7	3.7
Liver	PLCPRF5	4
Liver	SKHEP1	3.8
Liver	SNU182	3.8
Liver	SNU387	3.8
Liver	SNU398	3.6
Liver	SNU423	3.8
Liver	SNU449	4
Liver	SNU475	3.8
Liver	SNU761	3.7
Liver	SNU878	4
Liver	SNU886	3.6
Lung	A549	4
Lung	ABC1	3.8
Lung	BEN	3.8
Lung	CAL12T	4.1
Lung	CALU1	3.8
Lung	CALU3	3.8
Lung	CALU6	3.9
Lung	CHAGOK1	4
Lung	COLO668	3.9
Lung	COLO699	3.8
Lung	CORL105	3.6
Lung	CORL23	4
Lung	CORL24	3.6
Lung	CORL279	3.6
Lung	CORL311	4.3
Lung	CORL47	4
Lung	CORL51	3.7
Lung	CORL88	3.8
Lung	CORL95	3.7
Lung	CPCN	4
Lung	DMS114	3.7
Lung	DMS153	3.8
Lung	DMS273	3.8
Lung	DMS454	3.8
Lung	DMS53	3.7
Lung	DMS79	3.8
Lung	DV90	3.7
Lung	EBC1	3.8
Lung	EPLC272H	3.9
Lung	HARA	4.2
Lung	HCC1171	3.4
Lung	HCC1195	4
Lung	HCC15	4.2
Lung	HCC2279	3.7
Lung	HCC2935	3.7
Lung	HCC33	3.7
Lung	HCC366	3.8
Lung	HCC4006	3.7
Lung	HCC44	3.8
Lung	HCC78	3.7
Lung	HCC827	3.6
Lung	HCC95	3.8
Lung	HLC1	3.8
Lung	HLFA	3.9
Lung	HS229T	3.9
Lung	HS618T	3.7
Lung	IALM	3.6
Lung	KNS62	4.2
Lung	LC1F	4
Lung	LC1SQSF	4.2
Lung	LCLC103H	3.7
Lung	LCLC97TM1	3.6
Lung	LK2	4
Lung	LOUNH91	4
Lung	LU65	3.9
Lung	LU99	3.9
Lung	LUDLU1	3.9
Lung	LXF289	3.7
Lung	MORCPR	4.2
Lung	NCIH1048	3.6
Lung	NCIH1092	3.7
Lung	NCIH1105	3.6
Lung	NCIH1155	3.9
Lung	NCIH1184	3.9
Lung	NCIH1299	3.9
Lung	NCIH1339	3.8
Lung	NCIH1341	3.9
Lung	NCIH1355	3.7
Lung	NCIH1373	3.9
Lung	NCIH1385	3.9
Lung	NCIH1395	4
Lung	NCIH1435	3.9
Lung	NCIH1436	3.5
Lung	NCIH1437	4
Lung	NCIH146	4
Lung	NCIH1563	3.9
Lung	NCIH1568	4
Lung	NCIH1573	3.9
Lung	NCIH1581	3.8
Lung	NCIH1618	3.8
Lung	NCIH1623	3.9
Lung	NCIH1648	3.7
Lung	NCIH1650	3.9
Lung	NCIH1651	3.9
Lung	NCIH1666	3.6
Lung	NCIH1693	3.7
Lung	NCIH1694	3.9
Lung	NCIH1703	3.8
Lung	NCIH1734	3.9
Lung	NCIH1755	3.7
Lung	NCIH1781	3.8
Lung	NCIH1792	4.1
Lung	NCIH1793	3.8
Lung	NCIH1836	3.7
Lung	NCIH1838	4.2
Lung	NCIH1869	3.9
Lung	NCIH1876	3.7
Lung	NCIH1915	3.6
Lung	NCIH1930	3.8
Lung	NCIH1944	3.9
Lung	NCIH1963	3.6
Lung	NCIH196	3.8
Lung	NCIH1975	3.7
Lung	NCIH2009	3.9
Lung	NCIH2023	3.9
Lung	NCIH2029	3.8
Lung	NCIH2030	3.8
Lung	NCIH2066	4.1
Lung	NCIH2081	3.7
Lung	NCIH2085	4.2
Lung	NCIH2087	3.9
Lung	NCIH209	3.7
Lung	NCIH2106	3.9
Lung	NCIH2110	4
Lung	NCIH211	4
Lung	NCIH2122	4.2
Lung	NCIH2126	3.6
Lung	NCIH2141	3.9
Lung	NCIH2170	3.8
Lung	NCIH2171	4.1
Lung	NCIH2172	4.1
Lung	NCIH2196	3.9
Lung	NCIH2227	3.8
Lung	NCIH2228	3.7
Lung	NCIH226	3.7
Lung	NCIH2286	3.8
Lung	NCIH2291	4
Lung	NCIH2342	4
Lung	NCIH2347	3.8
Lung	NCIH23	4
Lung	NCIH2405	3.7
Lung	NCIH2444	4
Lung	NCIH292	3.8
Lung	NCIH322	4.3
Lung	NCIH3255	3.6
Lung	NCIH358	4.1
Lung	NCIH441	3.9
Lung	NCIH446	3.8
Lung	NCIH460	3.9
Lung	NCIH510	3.8
Lung	NCIH520	3.9
Lung	NCIH522	3.9
Lung	NCIH524	3.8
Lung	NCIH526	4
Lung	NCIH596	3.8
Lung	NCIH647	3.9
Lung	NCIH650	3.8
Lung	NCIH661	3.9
Lung	NCIH69	3.7
Lung	NCIH727	3.6
Lung	NCIH810	4
Lung	NCIH82	3.8
Lung	NCIH838	3.6
Lung	NCIH841	4
Lung	NCIH854	3.9
Lung	NCIH889	4
Lung	PC14	3.8
Lung	RERFLCAD1	3.8
Lung	RERFLCAD2	4.1
Lung	RERFLCAI	4
Lung	RERFLCKJ	4
Lung	RERFLCMS	3.8
Lung	RERFLCSQ1	3.8
Lung	SBC5	3.7
Lung	SCLC21H	3.8
Lung	SHP77	3.7
Lung	SKLU1	4.2
Lung	SKMES1	4.2
Lung	SQ1	4.3
Lung	SW1271	3.9
Lung	SW1573	3.8
Lung	SW900	4
Lung	VMRCLCD	3.8
Lung	VMRCLCP	3.7
Oesophagus	COLO680N	3.6
Oesophagus	ECGI10	3.7
Oesophagus	KYSE140	3.9
Oesophagus	KYSE150	3.9
Oesophagus	KYSE180	4
Oesophagus	KYSE270	3.8
Oesophagus	KYSE30	4
Oesophagus	KYSE410	4
Oesophagus	KYSE450	4
Oesophagus	KYSE510	3.8
Oesophagus	KYSE520	4
Oesophagus	KYSE70	4.1
Oesophagus	OE19	4.2
Oesophagus	OE33	3.8
Oesophagus	TE10	3.9
Oesophagus	TE11	4.2
Oesophagus	TE14	3.6
Oesophagus	TE15	4
Oesophagus	TE1	3.8
Oesophagus	TE4	3.6
Oesophagus	TE5	3.9
Oesophagus	TE6	3.7
Oesophagus	TE8	3.4
Oesophagus	TE9	3.9
Oesophagus	TT	3.9
Ovary	59M	3.8
Ovary	A2780	3.7
Ovary	CAOV3	3.8
Ovary	CAOV4	4
Ovary	COLO704	3.6
Ovary	COV318	4.3
Ovary	COV362	3.9
Ovary	COV434	4.1
Ovary	COV504	3.6
Ovary	COV644	4
Ovary	EFO21	4
Ovary	EFO27	4.2
Ovary	ES2	3.8
Ovary	FUOV1	3.9
Ovary	HEYA8	3.8
Ovary	HS571T	3.9
Ovary	IGROV1	4.2
Ovary	JHOC5	3.6
Ovary	JHOM1	3.5
Ovary	JHOM2B	3.5
Ovary	JHOS2	3.7
Ovary	JHOS4	3.9
Ovary	KURAMOCHI	3.5
Ovary	MCAS	3.9
Ovary	NIHOVCAR3	3.8
Ovary	OAW28	4.1
Ovary	OAW42	3.8
Ovary	OC314	3.7
Ovary	OC316	3.8
Ovary	ONCODG1	3.7
Ovary	OV56	3.9
Ovary	OV7	3.6
Ovary	OV90	4
Ovary	OVCAR4	3.8
Ovary	OVCAR8	4.1
Ovary	OVISE	4.1
Ovary	OVK18	3.8
Ovary	OVKATE	3.8
Ovary	OVMANA	4.4
Ovary	OVSAHO	4
Ovary	OVTOKO	4.2
Ovary	RMGI	4.3
Ovary	RMUGS	4.2
Ovary	SKOV3	3.9
Ovary	SNU119	3.6
Ovary	SNU840	3.7
Ovary	SNU8	3.9
Ovary	TOV112D	4.3
Ovary	TOV21G	3.9
Ovary	TYKNU	4.2
Pancreas	ASPC1	4.1
Pancreas	BXPC3	3.8
Pancreas	CAPAN1	3.8
Pancreas	CAPAN2	4
Pancreas	CFPAC1	4.1
Pancreas	DANG	3.8
Pancreas	HPAC	3.9
Pancreas	HPAFII	3.8
Pancreas	HS766T	4
Pancreas	HUPT3	4
Pancreas	HUPT4	4.1
Pancreas	KCIMOH1	4
Pancreas	KLM1	3.6
Pancreas	KP2	3.6
Pancreas	KP3	4
Pancreas	KP4	3.7
Pancreas	L33	3.8
Pancreas	MIAPACA2	3.8
Pancreas	PANC0203	3.8
Pancreas	PANC0213	4
Pancreas	PANC0327	3.9
Pancreas	PANC0403	3.9
Pancreas	PANC0504	3.8
Pancreas	PANC0813	3.8
Pancreas	PANC1005	3.9
Pancreas	PANC1	4.1
Pancreas	PATU8902	3.8
Pancreas	PATU8988S	3.9
Pancreas	PATU8988T	3.8
Pancreas	PK1	3.9
Pancreas	PK45H	3.9
Pancreas	PK59	4.3
Pancreas	PL45	3.9
Pancreas	PSN1	3.8
Pancreas	QGP1	3.8
Pancreas	SNU213	3.6
Pancreas	SNU324	3.6
Pancreas	SNU410	3.7
Pancreas	SU8686	3.8
Pancreas	SUIT2	4
Pancreas	SW1990	3.8
Pancreas	T3M4	4
Pancreas	TCCPAN2	4
Pancreas	YAPC	3.6
Pleura	ACCMESO1	3.7
Pleura	DM3	3.7
Pleura	ISTMES1	3.6
Pleura	ISTMES2	3.6
Pleura	JL1	3.8
Pleura	MPP89	3.8
Pleura	MSTO211H	3.9
Pleura	NCIH2052	3.5
Pleura	NCIH2452	3.8
Pleura	NCIH28	4.3
Prostate	22RV1	3.7
Prostate	DU145	3.7
Prostate	LNCAPCLONEFGC	3.8
Prostate	MDAPCA2B	3.8
Prostate	NCIH660	3.9
Prostate	PC3	4.1
Prostate	VCAP	3.7
Salivary gland	A253	3.7
Salivary gland	YD15	3.8
Skin	A101D	3.9
Skin	A2058	3.7
Skin	A375	4.1
Skin	C32	3.9
Skin	CHL1	3.8
Skin	CJM	3.6
Skin	COLO679	3.8
Skin	COLO741	4
Skin	COLO783	3.7
Skin	COLO792	4.1
Skin	COLO800	4.2
Skin	COLO818	3.9
Skin	COLO829	4.1
Skin	COLO849	3.7
Skin	G361	3.8
Skin	GRM	3.7
Skin	HMCB	3.7
Skin	HS294T	4
Skin	HS600T	3.8
Skin	HS688AT	3.7
Skin	HS695T	3.9
Skin	HS839T	4.1
Skin	HS852T	3.7
Skin	HS895T	3.8
Skin	HS934T	3.8
Skin	HS936T	4.2
Skin	HS939T	3.7
Skin	HS940T	3.7
Skin	HS944T	4.1
Skin	HT144	3.9
Skin	IGR1	3.7
Skin	IGR37	3.9
Skin	IGR39	3.9
Skin	IPC298	4
Skin	K029AX	3.8
Skin	LOXIMVI	3.8
Skin	MALME3M	3.9
Skin	MDAMB435S	3.7
Skin	MELHO	4.1
Skin	MELJUSO	4
Skin	MEWO	3.9
Skin	RPMI7951	3.7
Skin	RVH421	4.1
Skin	SH4	3.7
Skin	SKMEL1	4
Skin	SKMEL24	3.8
Skin	SKMEL28	4
Skin	SKMEL2	4
Skin	SKMEL30	3.7
Skin	SKMEL31	3.6
Skin	SKMEL3	4.1
Skin	SKMEL5	4.2
Skin	UACC257	4.1
Skin	UACC62	4.2
Skin	WM115	3.8
Skin	WM1799	3.8
Skin	WM2664	3.8
Skin	WM793	3.6
Skin	WM88	3.9
Skin	WM983B	4
Small intestine	HUTU80	4.2
Soft tissue	A204	3.8
Soft tissue	G401	3.9
Soft tissue	G402	4
Soft tissue	GCT	3.8
Soft tissue	HS729	3.6
Soft tissue	HT1080	3.9
Soft tissue	KYM1	4
Soft tissue	MESSA	3.9
Soft tissue	RD	6.4
Soft tissue	RH30	3.7
Soft tissue	RH41	4.2
Soft tissue	RKN	4.1
Soft tissue	S117	4.2
Soft tissue	SJRH30	4.9
Soft tissue	SKLMS1	4
Soft tissue	SKUT1	4.2
Soft tissue	TE125T	3.6
Soft tissue	TE159T	3.8
Soft tissue	TE441T	3.9
Soft tissue	TE617T	3.8
Stomach	2313287	3.6
Stomach	AGS	4
Stomach	AZ521	4
Stomach	ECC10	3.7
Stomach	ECC12	3.7
Stomach	FU97	3.9
Stomach	GCIY	4
Stomach	GSS	3.6
Stomach	GSU	3.5
Stomach	HGC27	3.8
Stomach	HS746T	3.6
Stomach	HUG1N	3.9
Stomach	IM95	3.8
Stomach	KATOIII	4.2
Stomach	KE39	4
Stomach	LMSU	3.7
Stomach	MKN1	3.8
Stomach	MKN45	3.8
Stomach	MKN74	3.6
Stomach	MKN7	3.9
Stomach	NCCSTCK140	3.4
Stomach	NCIN87	3.7
Stomach	NUGC2	3.9
Stomach	NUGC3	3.9
Stomach	NUGC4	4.4
Stomach	OCUM1	3.9
Stomach	RERFGC1B	3.9
Stomach	SH10TC	3.8
Stomach	SNU16	3.9
Stomach	SNU1	3.7
Stomach	SNU216	3.7
Stomach	SNU520	3.5
Stomach	SNU5	3.9
Stomach	SNU601	3.7
Stomach	SNU620	3.7
Stomach	SNU668	3.5
Stomach	SNU719	4
Stomach	TGBC11TKB	3.8
Thyroid	8305C	3.7
Thyroid	8505C	3.7
Thyroid	BCPAP	3.7
Thyroid	BHT101	3.7
Thyroid	CAL62	3.8
Thyroid	CGTHW1	3.7
Thyroid	FTC133	3.7
Thyroid	FTC238	3.7
Thyroid	ML1	3.5
Thyroid	SW579	3.9
Thyroid	TT2609C02	3.7
Thyroid	TT	3.9
Upper aerodigestive tract	BHY	3.7
Upper aerodigestive tract	BICR16	3.8
Upper aerodigestive tract	BICR18	3.8
Upper aerodigestive tract	BICR22	3.9
Upper aerodigestive tract	BICR31	3.8
Upper aerodigestive tract	BICR56	4
Upper aerodigestive tract	BICR6	3.9
Upper aerodigestive tract	CAL27	4
Upper aerodigestive tract	CAL33	3.6
Upper aerodigestive tract	DETROIT562	3.9
Upper aerodigestive tract	FADU	3.8
Upper aerodigestive tract	HS840T	3.8
Upper aerodigestive tract	HSC2	4
Upper aerodigestive tract	HSC3	3.8
Upper aerodigestive tract	HSC4	3.8
Upper aerodigestive tract	PECAPJ15	3.9
Upper aerodigestive tract	PECAPJ34CLONEC12	3.7
Upper aerodigestive tract	PECAPJ41CLONED2	4.1
Upper aerodigestive tract	PECAPJ49	3.8
Upper aerodigestive tract	SCC15	3.8
Upper aerodigestive tract	SCC25	4
Upper aerodigestive tract	SCC4	3.6
Upper aerodigestive tract	SCC9	3.7
Upper aerodigestive tract	SNU1076	4.1
Upper aerodigestive tract	SNU1214	3.5
Upper aerodigestive tract	SNU46	3.6
Upper aerodigestive tract	SNU899	3.9
Upper aerodigestive tract	YD10B	4
Upper aerodigestive tract	YD38	4
Upper aerodigestive tract	YD8	3.8
Urinary tract	5637	3.9
Urinary tract	639V	3.9
Urinary tract	647V	3.7
Urinary tract	BC3C	3.7
Urinary tract	BFTC905	3.7
Urinary tract	CAL29	3.8
Urinary tract	HS172T	3.6
Urinary tract	HT1197	3.9
Urinary tract	HT1376	3.8
Urinary tract	J82	4
Urinary tract	JMSU1	3.6
Urinary tract	KMBC2	3.6
Urinary tract	KU1919	3.8
Urinary tract	RT11284	3.6
Urinary tract	RT112	4.1
Urinary tract	RT4	4
Urinary tract	SCABER	4
Urinary tract	SW1710	3.8
Urinary tract	SW780	3.6
Urinary tract	T24	3.7
Urinary tract	TCCSUP	3.6
Urinary tract	UMUC1	4
Urinary tract	UMUC3	4
Urinary tract	VMCUB1	3.9

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	0
Adrenal gland	0
Appendix	0.3
Bone marrow	0
Breast	6.3
Cerebral cortex	1.6
Cervix, uterine	0
Colon	1.9
Duodenum	2.1
Endometrium	0
Epididymis	0
Esophagus	7.7
Fallopian tube	0
Gallbladder	0.1
Heart muscle	98.8
Kidney	0
Liver	0
Lung	0
Lymph node	0
Ovary	0
Pancreas	0
Parathyroid gland	11.4
Placenta	0
Prostate	4.9
Rectum	2.2
Salivary gland	0
Seminal vesicle	0
Skeletal muscle	170.8
Skin	0
Small intestine	3.5
Smooth muscle	38
Spleen	0
Stomach	0.2
Testis	0.6
Thyroid gland	0
Tonsil	0
Urinary bladder	0

> Text Mining based Expression

[ TOP ]

PMID	Expression	Cancer	Evidence
25644430	Overexpression	Rhabdomyosarcoma	SMYD1 and G6PD modulation are critical events for miR-206-mediated differentiation of rhabdomyosarcoma.; SMYD1, one of the most highly upregulated genes, is a H3K4 histone methyltransferase.

Summary
Symbol	SMYD1
Name	SET and MYND domain containing 1
Aliases	ZMYND22; KMT3D; ZMYND18; CD8 beta opposite; SET and MYND domain-containing protein 1; zinc finger, MYND doma ......
Location	2p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BRCA	Breast invasive carcinoma	1075	0.083	0.00653	15.7	69.4	14.9	Neutral
COAD	Colon adenocarcinoma	449	0.022	0.645	1.8	81.1	17.1	Neutral
ESCA	Esophageal carcinoma	183	-0.027	0.717	6	58.5	35.5	Gain
GBM	Glioblastoma multiforme	147	0.081	0.327	6.1	85.7	8.2	Neutral
HNSC	Head and Neck squamous cell carcinoma	514	-0.015	0.728	5.8	73.9	20.2	Neutral
LGG	Brain Lower Grade Glioma	513	0.061	0.169	3.9	93.6	2.5	Neutral
PRAD	Prostate adenocarcinoma	491	0.024	0.593	5.9	91.4	2.6	Neutral
READ	Rectum adenocarcinoma	164	0.081	0.304	6.7	71.3	22	Neutral
SARC	Sarcoma	255	-0.028	0.661	21.2	56.9	22	Neutral
SKCM	Skin Cutaneous Melanoma	367	0.143	0.00613	13.4	68.7	18	Neutral
STAD	Stomach adenocarcinoma	413	0.005	0.919	4.1	78.2	17.7	Neutral
TGCT	Testicular Germ Cell Tumors	150	0.04	0.629	6	62.7	31.3	Neutral

Summary
Symbol	SMYD1
Name	SET and MYND domain containing 1
Aliases	ZMYND22; KMT3D; ZMYND18; CD8 beta opposite; SET and MYND domain-containing protein 1; zinc finger, MYND doma ......
Location	2p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

[ TOP ]

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BRCA	Breast invasive carcinoma	-0.361	0	83	785	0.121	3e-26	NS/NA
COAD	Colon adenocarcinoma	-0.242	1.45e-05	19	297	0.014	0.211	NS/NA
ESCA	Esophageal carcinoma	-0.06	0.404	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.222	0.0759	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.16	0.000195	20	522	-0.026	0.00903	NS/NA
LGG	Brain Lower Grade Glioma	-0.175	5.51e-05	0	530	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.043	0.316	35	498	-0.022	1.87e-10	NS/NA
READ	Rectum adenocarcinoma	-0.176	0.0791	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.348	8.34e-09	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.066	0.153	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.292	1.16e-08	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.26	0.00107	0	156	NA	NA	NS/NA

Summary
Symbol	SMYD1
Name	SET and MYND domain containing 1
Aliases	ZMYND22; KMT3D; ZMYND18; CD8 beta opposite; SET and MYND domain-containing protein 1; zinc finger, MYND doma ......
Location	2p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Level	Level Name
Adrenal gland	0	Not detected
Appendix	0	Not detected
Bone marrow	0	Not detected
Breast	0	Not detected
Bronchus	0	Not detected
Caudate	0	Not detected
Cerebellum	0	Not detected
Cerebral cortex	0	Not detected
Cervix, uterine	0	Not detected
Colon	0	Not detected
Duodenum	0	Not detected
Endometrium	0	Not detected
Epididymis	0	Not detected
Esophagus	0	Not detected
Fallopian tube	0	Not detected
Gallbladder	0	Not detected
Heart muscle	2	Medium
Hippocampus	0	Not detected
Kidney	0	Not detected
Liver	0	Not detected
Lung	0	Not detected
Lymph node	0	Not detected
Nasopharynx	0	Not detected
Oral mucosa	0	Not detected
Ovary	0	Not detected
Pancreas	0	Not detected
Parathyroid gland	0	Not detected
Placenta	0	Not detected
Prostate	0	Not detected
Rectum	0	Not detected
Salivary gland	0	Not detected
Seminal vesicle	0	Not detected
Skeletal muscle	2	Medium
Skin	0	Not detected
Small intestine	0	Not detected
Smooth muscle	0	Not detected
Soft tissue	0	Not detected
Spleen	0	Not detected
Stomach	0	Not detected
Testis	0	Not detected
Thyroid gland	0	Not detected
Tonsil	0	Not detected
Urinary bladder	0	Not detected
Vagina	0	Not detected

Summary
Symbol	SMYD1
Name	SET and MYND domain containing 1
Aliases	ZMYND22; KMT3D; ZMYND18; CD8 beta opposite; SET and MYND domain-containing protein 1; zinc finger, MYND doma ......
Location	2p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BRCA	Breast invasive carcinoma	521	1.76e-19	Significant	23000897
COAD	Colon adenocarcinoma	149	0.549	NS	22810696
GBM	Glioblastoma multiforme	157	0.00836	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	2.55e-08	Significant	25631445
LGG	Brain Lower Grade Glioma	513	0.00027	Significant	26824661
PRAD	Prostate adenocarcinoma	333	0.00095	Significant	26544944
READ	Rectum adenocarcinoma	67	0.138	NS	22810696
SKCM	Skin Cutaneous Melanoma	315	0.131	NS	26091043
STAD	Stomach adenocarcinoma	277	1.26e-05	Significant	25079317

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BRCA	Breast invasive carcinoma	1079	0.654	0.0632	NS
COAD	Colon adenocarcinoma	439	1.011	0.969	NS
ESCA	Esophageal carcinoma	184	1.102	0.786	NS
GBM	Glioblastoma multiforme	158	0.956	0.842	NS
HNSC	Head and Neck squamous cell carcinoma	518	1.667	0.00928	Shorter
LGG	Brain Lower Grade Glioma	511	1.183	0.528	NS
PRAD	Prostate adenocarcinoma	497	0.85	0.843	NS
READ	Rectum adenocarcinoma	159	1.465	0.466	NS
SARC	Sarcoma	259	0.647	0.128	NS
SKCM	Skin Cutaneous Melanoma	459	1.122	0.538	NS
STAD	Stomach adenocarcinoma	388	1.376	0.132	NS
TGCT	Testicular Germ Cell Tumors	134	0	0.239	NS

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BRCA	Breast invasive carcinoma	1071	-0.055	0.0732	NS
COAD	Colon adenocarcinoma	445	0.053	0.263	NS
ESCA	Esophageal carcinoma	162	0.044	0.582	NS
HNSC	Head and Neck squamous cell carcinoma	448	-0.108	0.0223	Lower
READ	Rectum adenocarcinoma	156	0.059	0.464	NS
SKCM	Skin Cutaneous Melanoma	410	0.028	0.572	NS
STAD	Stomach adenocarcinoma	392	0.032	0.525	NS
TGCT	Testicular Germ Cell Tumors	81	-0.241	0.0304	Lower

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
HNSC	Head and Neck squamous cell carcinoma	498	-0.032	0.473	NS
LGG	Brain Lower Grade Glioma	514	-0.021	0.636	NS
STAD	Stomach adenocarcinoma	406	0.18	0.000266	Higher

Summary
Symbol	SMYD1
Name	SET and MYND domain containing 1
Aliases	ZMYND22; KMT3D; ZMYND18; CD8 beta opposite; SET and MYND domain-containing protein 1; zinc finger, MYND doma ......
Location	2p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	SMYD1
Name	SET and MYND domain containing 1
Aliases	ZMYND22; KMT3D; ZMYND18; CD8 beta opposite; SET and MYND domain-containing protein 1; zinc finger, MYND doma ......
Location	2p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for SMYD1.

Summary
Symbol	SMYD1
Name	SET and MYND domain containing 1
Aliases	ZMYND22; KMT3D; ZMYND18; CD8 beta opposite; SET and MYND domain-containing protein 1; zinc finger, MYND doma ......
Location	2p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining [ TOP ]
There is no record for SMYD1.