Summary | |
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Symbol | VCPKMT |
Name | valosin containing protein lysine methyltransferase |
Aliases | VCP-KMT; C14orf138; METTL21D; chromosome 14 open reading frame 138; methyltransferase like 21D; VCP lysine m ...... |
Location | 14q21.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway |
Domain |
PF10294 Lysine methyltransferase |
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Function |
Protein-lysine N-methyltransferase that specifically trimethylates 'Lys-315' of VCP/p97; this modification may decrease VCP ATPase activity. |
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Classification |
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Biological Process |
GO:0006479 protein methylation GO:0008213 protein alkylation GO:0018022 peptidyl-lysine methylation GO:0018023 peptidyl-lysine trimethylation GO:0018205 peptidyl-lysine modification GO:0032259 methylation GO:0043414 macromolecule methylation |
Molecular Function |
GO:0008168 methyltransferase activity GO:0008170 N-methyltransferase activity GO:0008276 protein methyltransferase activity GO:0008757 S-adenosylmethionine-dependent methyltransferase activity GO:0016278 lysine N-methyltransferase activity GO:0016279 protein-lysine N-methyltransferase activity GO:0016741 transferase activity, transferring one-carbon groups |
Cellular Component | - |
KEGG | - |
Reactome |
R-HSA-392499: Metabolism of proteins R-HSA-597592: Post-translational protein modification R-HSA-8876725: Protein methylation |
Summary | |
---|---|
Symbol | VCPKMT |
Name | valosin containing protein lysine methyltransferase |
Aliases | VCP-KMT; C14orf138; METTL21D; chromosome 14 open reading frame 138; methyltransferase like 21D; VCP lysine m ...... |
Location | 14q21.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining |
There is no record. |
|
There is no record for VCPKMT. |
Summary | |
---|---|
Symbol | VCPKMT |
Name | valosin containing protein lysine methyltransferase |
Aliases | VCP-KMT; C14orf138; METTL21D; chromosome 14 open reading frame 138; methyltransferase like 21D; VCP lysine m ...... |
Location | 14q21.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Post-translational modification (PTM) |
Filter By:
|
Summary | |
---|---|
Symbol | VCPKMT |
Name | valosin containing protein lysine methyltransferase |
Aliases | VCP-KMT; C14orf138; METTL21D; chromosome 14 open reading frame 138; methyltransferase like 21D; VCP lysine m ...... |
Location | 14q21.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change |
Differential expression analysis for cancers with more than 10 normal samples
|
There is no record. |
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There is no record. |
Summary | |
---|---|
Symbol | VCPKMT |
Name | valosin containing protein lysine methyltransferase |
Aliases | VCP-KMT; C14orf138; METTL21D; chromosome 14 open reading frame 138; methyltransferase like 21D; VCP lysine m ...... |
Location | 14q21.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Somatic copy number alteration in primary tomur tissue |
There is no record. |
Summary | |
---|---|
Symbol | VCPKMT |
Name | valosin containing protein lysine methyltransferase |
Aliases | VCP-KMT; C14orf138; METTL21D; chromosome 14 open reading frame 138; methyltransferase like 21D; VCP lysine m ...... |
Location | 14q21.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Methylation level in the promoter region of CR |
Correlation between expression and methylation as well as differential methylation analysis.
|
Summary | |
---|---|
Symbol | VCPKMT |
Name | valosin containing protein lysine methyltransferase |
Aliases | VCP-KMT; C14orf138; METTL21D; chromosome 14 open reading frame 138; methyltransferase like 21D; VCP lysine m ...... |
Location | 14q21.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Primary tumor tissue from TCGA > Normal tumor tissue from HPA |
There is no record. |
|
Summary | |
---|---|
Symbol | VCPKMT |
Name | valosin containing protein lysine methyltransferase |
Aliases | VCP-KMT; C14orf138; METTL21D; chromosome 14 open reading frame 138; methyltransferase like 21D; VCP lysine m ...... |
Location | 14q21.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade |
Association between expresson and subtype.
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Overall survival analysis based on expression.
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Association between expresson and stage.
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Association between expresson and grade.
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Summary | |
---|---|
Symbol | VCPKMT |
Name | valosin containing protein lysine methyltransferase |
Aliases | VCP-KMT; C14orf138; METTL21D; chromosome 14 open reading frame 138; methyltransferase like 21D; VCP lysine m ...... |
Location | 14q21.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data |
Summary | |
---|---|
Symbol | VCPKMT |
Name | valosin containing protein lysine methyltransferase |
Aliases | VCP-KMT; C14orf138; METTL21D; chromosome 14 open reading frame 138; methyltransferase like 21D; VCP lysine m ...... |
Location | 14q21.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Drugs from DrugBank database |
There is no record for VCPKMT. |
Summary | |
---|---|
Symbol | VCPKMT |
Name | valosin containing protein lysine methyltransferase |
Aliases | VCP-KMT; C14orf138; METTL21D; chromosome 14 open reading frame 138; methyltransferase like 21D; VCP lysine m ...... |
Location | 14q21.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining |
There is no record for VCPKMT. |
There is no record for VCPKMT. |