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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-31-5p A1CF -1.14 0.00993 0.3 0.356 MirTarget -0.18 0.0002 NA
2 hsa-miR-19a-3p ABCA1 0.49 0.05125 -0.05 0.8308 miRNAWalker2 validate; MirTarget; miRNATAP -0.34 0 27445062 The target genes of miR-19a such as ABCA1 and PTEN that had been suppressed by miR recovered their expression through CAP treatment
3 hsa-miR-374a-5p ABCA1 0.32 0.07709 -0.05 0.8308 mirMAP -0.24 0.0151 NA
4 hsa-miR-374a-5p ABCA8 0.32 0.07709 -0.04 0.9471 MirTarget; mirMAP -1.07 0.00012 NA
5 hsa-miR-374a-5p ABCA9 0.32 0.07709 -0.34 0.34766 mirMAP -0.86 0 NA
6 hsa-miR-374a-5p ABCC9 0.32 0.07709 -0.58 0.0487 mirMAP -0.66 1.0E-5 NA
7 hsa-miR-30d-5p ABCD2 0.02 0.95554 -0.21 0.52359 MirTarget -0.57 7.0E-5 NA
8 hsa-miR-940 ABHD2 0.68 0.01127 -0.28 0.26486 mirMAP -0.12 0.00327 NA
9 hsa-miR-940 ABHD4 0.68 0.01127 -0.44 0.00815 miRNATAP -0.13 8.0E-5 NA
10 hsa-miR-374a-5p ABI3BP 0.32 0.07709 -0.52 0.15667 mirMAP -0.68 0.0003 NA
11 hsa-miR-30d-5p ACTC1 0.02 0.95554 -1.15 0.01754 MirTarget; miRNATAP -0.98 1.0E-5 NA
12 hsa-miR-19a-3p ACTN1 0.49 0.05125 -0.3 0.15193 miRNATAP -0.17 0 NA
13 hsa-miR-30d-5p ACTN1 0.02 0.95554 -0.3 0.15193 miRNATAP -0.16 0.00035 NA
14 hsa-miR-374a-5p ACTN1 0.32 0.07709 -0.3 0.15193 MirTarget -0.29 0 NA
15 hsa-miR-30d-5p ACTR1A 0.02 0.95554 -0.13 0.46922 miRNATAP -0.14 0 NA
16 hsa-miR-365a-3p ADAM10 -0.07 0.70333 -0.12 0.5009 MirTarget -0.18 0.00039 NA
17 hsa-miR-374a-5p ADAM10 0.32 0.07709 -0.12 0.5009 MirTarget; mirMAP -0.12 0.04102 NA
18 hsa-miR-30d-5p ADAM11 0.02 0.95554 -0.4 0.1814 miRNATAP -0.48 0.00037 NA
19 hsa-miR-19a-3p ADAM12 0.49 0.05125 -0.97 0.00809 miRNATAP -0.62 0 NA
20 hsa-miR-374a-5p ADAM12 0.32 0.07709 -0.97 0.00809 mirMAP -0.7 0.00016 NA
21 hsa-miR-30d-5p ADAM19 0.02 0.95554 -0.05 0.83067 MirTarget; miRNATAP -0.48 0 NA
22 hsa-miR-19a-3p ADAM28 0.49 0.05125 -0.48 0.15863 mirMAP -0.55 0 NA
23 hsa-miR-374a-5p ADAM28 0.32 0.07709 -0.48 0.15863 mirMAP -0.66 0.00018 NA
24 hsa-miR-940 ADAMTS14 0.68 0.01127 -0.2 0.32507 mirMAP -0.11 0.0176 NA
25 hsa-miR-374a-5p ADAMTS16 0.32 0.07709 -0.8 0.07095 mirMAP -0.97 2.0E-5 NA
26 hsa-miR-19a-3p ADAMTS18 0.49 0.05125 -0.38 0.34192 miRNATAP -0.74 0 NA
27 hsa-miR-374a-5p ADAMTS19 0.32 0.07709 -0.14 0.7796 mirMAP -0.78 0.00177 NA
28 hsa-miR-30d-5p ADAMTS3 0.02 0.95554 -0.66 0.00414 miRNATAP -0.37 0.00039 NA
29 hsa-miR-374a-5p ADAMTS3 0.32 0.07709 -0.66 0.00414 mirMAP -0.36 0.00263 NA
30 hsa-miR-940 ADAMTS4 0.68 0.01127 -0.28 0.27653 MirTarget -0.15 0.01195 NA
31 hsa-miR-374a-5p ADAMTS5 0.32 0.07709 -0.21 0.26397 mirMAP -0.19 0.03939 NA
32 hsa-miR-30d-5p ADAMTS9 0.02 0.95554 -0.24 0.27035 miRNATAP -0.22 0.00949 NA
33 hsa-miR-19a-3p ADAMTSL3 0.49 0.05125 -0.46 0.25267 miRNATAP -0.93 0 NA
34 hsa-miR-374a-5p ADAMTSL3 0.32 0.07709 -0.46 0.25267 MirTarget; mirMAP -0.82 8.0E-5 NA
35 hsa-miR-940 ADAMTSL4 0.68 0.01127 -0.41 0.09478 MirTarget -0.27 1.0E-5 NA
36 hsa-miR-30d-5p ADAP2 0.02 0.95554 -0.34 0.05871 miRNAWalker2 validate -0.26 0.00139 NA
37 hsa-miR-19a-3p ADARB1 0.49 0.05125 -0.28 0.08336 mirMAP -0.18 1.0E-5 NA
38 hsa-miR-19a-3p ADCY1 0.49 0.05125 -0.69 0.01679 miRNATAP -0.18 0.03677 NA
39 hsa-miR-31-5p ADCY1 -1.14 0.00993 -0.69 0.01679 mirMAP -0.11 0.01834 NA
40 hsa-miR-625-5p ADCY1 -0.3 0.25393 -0.69 0.01679 mirMAP -0.28 0.00024 NA
41 hsa-miR-19a-3p ADCY7 0.49 0.05125 -0.23 0.2293 miRNATAP -0.15 0.00163 NA
42 hsa-miR-19a-3p ADCY9 0.49 0.05125 -0.18 0.26271 miRNATAP -0.12 0.00155 NA
43 hsa-miR-374a-5p ADCYAP1 0.32 0.07709 -0.2 0.67185 MirTarget; mirMAP -1 3.0E-5 NA
44 hsa-miR-940 ADD2 0.68 0.01127 -0.98 0.01735 miRNATAP -0.42 5.0E-5 NA
45 hsa-miR-365a-3p ADD3 -0.07 0.70333 0.25 0.22886 MirTarget; miRNATAP -0.11 0.04146 NA
46 hsa-miR-940 ADIPOQ 0.68 0.01127 -0.49 0.50915 MirTarget -0.75 5.0E-5 NA
47 hsa-miR-30d-5p ADRA1D 0.02 0.95554 -0.14 0.64206 MirTarget; miRNATAP -0.49 0.00018 NA
48 hsa-miR-19a-3p AFAP1 0.49 0.05125 -0.16 0.3649 mirMAP -0.1 0.00209 NA
49 hsa-miR-625-5p AFAP1 -0.3 0.25393 -0.16 0.3649 mirMAP -0.11 0.00021 NA
50 hsa-miR-940 AFAP1L1 0.68 0.01127 -0.58 0.00318 MirTarget; miRNATAP -0.21 3.0E-5 NA
51 hsa-miR-374a-5p AFF1 0.32 0.07709 -0.14 0.42356 MirTarget -0.16 0.00088 NA
52 hsa-miR-19a-3p AFF2 0.49 0.05125 -0.19 0.58722 mirMAP -0.5 0 NA
53 hsa-miR-30d-5p AFF2 0.02 0.95554 -0.19 0.58722 mirMAP -0.55 0.00055 NA
54 hsa-miR-940 AFF2 0.68 0.01127 -0.19 0.58722 miRNATAP -0.21 0.02038 NA
55 hsa-miR-374a-5p AFF3 0.32 0.07709 -0.89 0.00696 mirMAP -0.49 0.00383 NA
56 hsa-miR-374a-5p AFF4 0.32 0.07709 -0.05 0.75124 MirTarget; miRNATAP -0.18 4.0E-5 NA
57 hsa-miR-19a-3p AGPAT4 0.49 0.05125 -0.78 0.00264 mirMAP -0.48 0 NA
58 hsa-miR-30d-5p AHNAK 0.02 0.95554 -0.62 0.01795 miRNATAP -0.35 2.0E-5 NA
59 hsa-miR-374a-5p AHR 0.32 0.07709 -0.22 0.27384 MirTarget -0.18 0.00943 NA
60 hsa-miR-374a-5p AIF1L 0.32 0.07709 -1.04 0.00016 mirMAP -0.71 0 NA
61 hsa-miR-365a-3p AKAP10 -0.07 0.70333 -0.05 0.70308 MirTarget -0.13 0.00089 NA
62 hsa-miR-19a-3p AKAP2 0.49 0.05125 0.17 0.40729 mirMAP -0.37 0 NA
63 hsa-miR-374a-5p AKAP2 0.32 0.07709 0.17 0.40729 mirMAP -0.37 0.00021 NA
64 hsa-miR-374a-5p AKAP6 0.32 0.07709 -0.25 0.2393 mirMAP -0.41 0.00014 NA
65 hsa-miR-374a-5p AKT3 0.32 0.07709 -0.59 0.01641 mirMAP -0.58 0 NA
66 hsa-miR-30d-5p ALDH1A3 0.02 0.95554 -0.12 0.66251 mirMAP -0.35 0.00243 NA
67 hsa-miR-30d-5p ALPK3 0.02 0.95554 0.32 0.37339 miRNATAP -0.41 0.01186 NA
68 hsa-miR-374a-5p ALS2 0.32 0.07709 -0.15 0.26183 mirMAP -0.13 0.00437 NA
69 hsa-miR-30d-5p AMOTL1 0.02 0.95554 -0.76 0.00615 MirTarget; miRNATAP -0.53 2.0E-5 NA
70 hsa-miR-374a-5p AMOTL1 0.32 0.07709 -0.76 0.00615 mirMAP -0.64 0 NA
71 hsa-miR-374a-5p ANGPT2 0.32 0.07709 -0.17 0.32152 mirMAP -0.16 0.04809 NA
72 hsa-miR-940 ANK1 0.68 0.01127 -0.49 0.10644 MirTarget; PITA; miRNATAP -0.18 0.02433 NA
73 hsa-miR-625-5p ANK2 -0.3 0.25393 -0.5 0.13109 MirTarget -0.63 0 NA
74 hsa-miR-365a-3p ANKRD11 -0.07 0.70333 0.04 0.82831 MirTarget -0.1 0.00317 NA
75 hsa-miR-19a-3p ANKRD12 0.49 0.05125 -0.23 0.13851 miRNATAP -0.14 2.0E-5 NA
76 hsa-miR-365a-3p ANKRD12 -0.07 0.70333 -0.23 0.13851 miRNAWalker2 validate -0.1 0.03571 NA
77 hsa-miR-374a-5p ANKRD12 0.32 0.07709 -0.23 0.13851 mirMAP -0.23 3.0E-5 NA
78 hsa-miR-365a-3p ANKS1A -0.07 0.70333 -0 0.98116 MirTarget -0.12 0.00063 NA
79 hsa-miR-19a-3p ANO1 0.49 0.05125 -1.17 0.00028 MirTarget; miRNATAP -0.41 1.0E-5 NA
80 hsa-miR-19a-3p ANTXR1 0.49 0.05125 -0.67 0.04479 MirTarget; mirMAP -0.66 0 NA
81 hsa-miR-30d-5p ANTXR1 0.02 0.95554 -0.67 0.04479 mirMAP -0.59 3.0E-5 NA
82 hsa-miR-374a-5p ANTXR1 0.32 0.07709 -0.67 0.04479 MirTarget; mirMAP -0.63 8.0E-5 NA
83 hsa-miR-30d-5p ANTXR2 0.02 0.95554 -0.51 0.01287 mirMAP -0.32 1.0E-5 NA
84 hsa-miR-374a-5p ANTXR2 0.32 0.07709 -0.51 0.01287 mirMAP -0.43 0 NA
85 hsa-miR-940 ANTXR2 0.68 0.01127 -0.51 0.01287 miRNATAP -0.25 0 NA
86 hsa-miR-940 AOC3 0.68 0.01127 -0.71 0.02461 MirTarget -0.44 0 NA
87 hsa-miR-30d-5p AP2A1 0.02 0.95554 0.01 0.97662 miRNATAP -0.1 0.0004 NA
88 hsa-miR-940 APBB1 0.68 0.01127 -0.19 0.42292 miRNATAP -0.17 0.00477 NA
89 hsa-miR-374a-5p APC 0.32 0.07709 -0.2 0.20512 mirMAP -0.28 0 NA
90 hsa-miR-625-5p APLNR -0.3 0.25393 -0.59 0.01608 MirTarget -0.32 0 NA
91 hsa-miR-940 APLNR 0.68 0.01127 -0.59 0.01608 MirTarget -0.23 0.00015 NA
92 hsa-miR-625-5p APOC2 -0.3 0.25393 0.31 0.37748 mirMAP -0.42 0 NA
93 hsa-miR-19a-3p AQP5 0.49 0.05125 -0.6 0.36932 MirTarget -0.45 0.02473 NA
94 hsa-miR-19a-3p AR 0.49 0.05125 -0.72 0.08465 mirMAP -0.85 0 NA
95 hsa-miR-30d-5p AR 0.02 0.95554 -0.72 0.08465 mirMAP -0.58 0.00147 27683042 Inhibition of endogenous miR-30b-3p and miR-30d-5p enhanced AR expression and androgen-independent cell growth; MiR-30d-5p levels were inversely correlated with AR activity as measured by PSA mRNA in metastatic CRPC
96 hsa-miR-19a-3p ARC 0.49 0.05125 -0.6 0.13485 miRNATAP -0.27 0.02545 NA
97 hsa-miR-19a-3p ARHGAP1 0.49 0.05125 -0.34 0.05875 MirTarget; miRNATAP -0.11 0 NA
98 hsa-miR-374a-5p ARHGAP20 0.32 0.07709 -1 0.00162 MirTarget -0.76 0 NA
99 hsa-miR-374a-5p ARHGAP29 0.32 0.07709 -0.14 0.48042 mirMAP -0.41 1.0E-5 NA
100 hsa-miR-940 ARHGAP31 0.68 0.01127 -0.49 0.01871 miRNATAP -0.31 0 NA
101 hsa-miR-374a-5p ARHGAP5 0.32 0.07709 -0.19 0.28061 mirMAP -0.11 0.02244 NA
102 hsa-miR-19a-3p ARHGEF4 0.49 0.05125 -0.84 0.02055 mirMAP -0.34 0.00189 NA
103 hsa-miR-940 ARHGEF4 0.68 0.01127 -0.84 0.02055 mirMAP -0.25 0.00673 NA
104 hsa-miR-30d-5p ARHGEF6 0.02 0.95554 -0.48 0.03477 MirTarget; miRNATAP -0.34 0.00099 NA
105 hsa-miR-31-5p ARID3A -1.14 0.00993 0.87 0.00041 mirMAP -0.19 0 NA
106 hsa-miR-374a-5p ARID4B 0.32 0.07709 -0.03 0.81567 miRNATAP -0.13 0.00093 NA
107 hsa-miR-19a-3p ARID5B 0.49 0.05125 -0.01 0.94405 miRNATAP -0.11 0.0009 NA
108 hsa-miR-30d-5p ARID5B 0.02 0.95554 -0.01 0.94405 MirTarget; miRNATAP -0.15 0.00355 NA
109 hsa-miR-19a-3p ARL10 0.49 0.05125 -0.13 0.63188 mirMAP -0.29 0.00018 NA
110 hsa-miR-625-5p ARL10 -0.3 0.25393 -0.13 0.63188 mirMAP -0.51 0 NA
111 hsa-miR-30d-5p ARL4C 0.02 0.95554 -0.39 0.13323 miRNATAP -0.36 0.00075 NA
112 hsa-miR-374a-5p ARNT 0.32 0.07709 -0.16 0.27143 mirMAP -0.17 1.0E-5 NA
113 hsa-miR-19a-3p ARRDC3 0.49 0.05125 -0.14 0.4571 MirTarget; miRNATAP -0.15 0.00012 NA
114 hsa-miR-19a-3p ARRDC4 0.49 0.05125 -0.49 0.00995 MirTarget; miRNATAP -0.18 0.0001 NA
115 hsa-miR-940 ARSB 0.68 0.01127 -0.61 0.0002 MirTarget -0.11 0.002 NA
116 hsa-miR-374a-5p ARSJ 0.32 0.07709 -0.84 0.00448 mirMAP -0.69 0 NA
117 hsa-miR-625-5p ASAP1 -0.3 0.25393 0.16 0.3669 MirTarget -0.2 0 NA
118 hsa-miR-625-5p ASH1L -0.3 0.25393 -0.03 0.84891 miRNAWalker2 validate -0.11 3.0E-5 NA
119 hsa-miR-940 ASPHD2 0.68 0.01127 -0.62 0.00964 miRNATAP -0.13 0.0196 NA
120 hsa-miR-374a-5p ASPN 0.32 0.07709 -0.37 0.33577 MirTarget -0.7 0.00039 NA
121 hsa-miR-374a-5p ATF2 0.32 0.07709 0.01 0.9159 mirMAP -0.1 0.02795 NA
122 hsa-miR-19a-3p ATL3 0.49 0.05125 -0.41 0.01007 mirMAP -0.11 0.00319 NA
123 hsa-miR-30d-5p ATL3 0.02 0.95554 -0.41 0.01007 mirMAP -0.13 0.01803 NA
124 hsa-miR-19a-3p ATP10A 0.49 0.05125 -0.48 0.07791 MirTarget -0.51 0 NA
125 hsa-miR-374a-5p ATP10D 0.32 0.07709 -0.05 0.77014 MirTarget; mirMAP -0.4 0 NA
126 hsa-miR-30d-5p ATP11C 0.02 0.95554 0.22 0.13309 mirMAP -0.11 0.02151 NA
127 hsa-miR-19a-3p ATP1A2 0.49 0.05125 -0.33 0.54434 MirTarget -1.35 0 NA
128 hsa-miR-625-5p ATP1B2 -0.3 0.25393 -0.35 0.21439 MirTarget; mirMAP -0.45 0 NA
129 hsa-miR-940 ATP1B2 0.68 0.01127 -0.35 0.21439 MirTarget; PITA; miRNATAP -0.29 6.0E-5 NA
130 hsa-miR-625-5p ATP2B4 -0.3 0.25393 -0.34 0.13246 MirTarget -0.28 0 NA
131 hsa-miR-30d-5p ATP6V1B2 0.02 0.95554 -0.4 0.03421 MirTarget -0.17 0.00268 NA
132 hsa-miR-30d-5p ATP8B2 0.02 0.95554 -0.6 0.01739 miRNATAP -0.5 1.0E-5 NA
133 hsa-miR-625-5p ATP8B2 -0.3 0.25393 -0.6 0.01739 mirMAP -0.35 0 NA
134 hsa-miR-940 ATP8B4 0.68 0.01127 -0.39 0.03667 MirTarget -0.24 0 NA
135 hsa-miR-625-5p ATRN -0.3 0.25393 -0.04 0.82833 mirMAP -0.13 0.00317 NA
136 hsa-miR-940 ATRN 0.68 0.01127 -0.04 0.82833 MirTarget -0.1 0.01804 NA
137 hsa-miR-30d-5p ATRNL1 0.02 0.95554 -0.66 0.11603 mirMAP -0.57 0.00222 NA
138 hsa-miR-374a-5p ATRNL1 0.32 0.07709 -0.66 0.11603 mirMAP -1.04 0 NA
139 hsa-miR-19a-3p ATXN1 0.49 0.05125 -0.19 0.22524 miRNAWalker2 validate; miRTarBase; miRNATAP -0.19 0 NA
140 hsa-miR-30d-5p ATXN1 0.02 0.95554 -0.19 0.22524 mirMAP; miRNATAP -0.12 0.02415 NA
141 hsa-miR-374a-5p ATXN1 0.32 0.07709 -0.19 0.22524 miRNATAP -0.2 0.00077 NA
142 hsa-miR-625-5p ATXN1 -0.3 0.25393 -0.19 0.22524 MirTarget -0.16 0 NA
143 hsa-miR-940 ATXN1 0.68 0.01127 -0.19 0.22524 MirTarget; PITA; miRNATAP -0.12 4.0E-5 NA
144 hsa-miR-374a-5p B3GALNT1 0.32 0.07709 -0.27 0.30827 mirMAP -0.49 0.0002 NA
145 hsa-miR-19a-3p BACH2 0.49 0.05125 -0.5 0.08578 mirMAP -0.62 0 NA
146 hsa-miR-30d-5p BACH2 0.02 0.95554 -0.5 0.08578 miRNATAP -0.49 0.00027 NA
147 hsa-miR-940 BACH2 0.68 0.01127 -0.5 0.08578 MirTarget; PITA; miRNATAP -0.41 0 NA
148 hsa-miR-374a-5p BBS12 0.32 0.07709 -0.12 0.38575 MirTarget -0.18 0.00631 NA
149 hsa-miR-625-5p BBS5 -0.3 0.25393 0.22 0.28368 mirMAP -0.21 0.0001 NA
150 hsa-miR-19a-3p BBX 0.49 0.05125 -0.17 0.24924 MirTarget; miRNATAP -0.12 0 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 257 1672 4.552e-40 2.118e-36
2 REGULATION OF CELL DIFFERENTIATION 229 1492 2.44e-35 5.676e-32
3 NEUROGENESIS 213 1402 4.146e-32 6.43e-29
4 CARDIOVASCULAR SYSTEM DEVELOPMENT 143 788 2.363e-29 2.199e-26
5 CIRCULATORY SYSTEM DEVELOPMENT 143 788 2.363e-29 2.199e-26
6 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 202 1395 1.41e-27 1.093e-24
7 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 176 1142 3.816e-27 2.22e-24
8 CELL DEVELOPMENT 204 1426 3.704e-27 2.22e-24
9 REGULATION OF CELL DEVELOPMENT 141 836 1.253e-25 6.479e-23
10 POSITIVE REGULATION OF CELL DIFFERENTIATION 136 823 7.221e-24 3.36e-21
11 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 156 1021 1.176e-23 4.975e-21
12 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 126 750 8.538e-23 3.311e-20
13 BIOLOGICAL ADHESION 155 1032 9.864e-23 3.531e-20
14 VASCULATURE DEVELOPMENT 94 469 1.168e-22 3.88e-20
15 REGULATION OF NEURON DIFFERENTIATION 101 554 4.647e-21 1.441e-18
16 REGULATION OF CELL PROJECTION ORGANIZATION 99 558 8.669e-20 2.521e-17
17 NEURON DIFFERENTIATION 132 874 1.235e-19 3.379e-17
18 TISSUE DEVELOPMENT 192 1518 3.047e-19 7.876e-17
19 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 168 1275 1.349e-18 3.303e-16
20 REGULATION OF NEURON PROJECTION DEVELOPMENT 79 408 2.783e-18 6.475e-16
21 CELL CELL ADHESION 99 608 3.878e-17 8.284e-15
22 REGULATION OF CELL MORPHOGENESIS 93 552 3.917e-17 8.284e-15
23 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 88 513 9.16e-17 1.853e-14
24 BLOOD VESSEL MORPHOGENESIS 71 364 9.958e-17 1.931e-14
25 LOCOMOTION 147 1114 2.21e-16 4.034e-14
26 REGULATION OF CELLULAR COMPONENT MOVEMENT 114 771 2.254e-16 4.034e-14
27 CELLULAR COMPONENT MORPHOGENESIS 126 900 4.163e-16 7.174e-14
28 POSITIVE REGULATION OF CELL DEVELOPMENT 82 472 5.016e-16 8.335e-14
29 INTRACELLULAR SIGNAL TRANSDUCTION 187 1572 5.671e-16 9.098e-14
30 HEART DEVELOPMENT 81 466 7.381e-16 1.145e-13
31 HOMOPHILIC CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 42 153 9.084e-16 1.364e-13
32 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 77 437 1.82e-15 2.647e-13
33 ORGAN MORPHOGENESIS 118 841 3.292e-15 4.641e-13
34 SKELETAL SYSTEM DEVELOPMENT 78 455 5.633e-15 7.709e-13
35 CELL CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 48 204 6.024e-15 8.009e-13
36 POSITIVE REGULATION OF RESPONSE TO STIMULUS 214 1929 6.487e-15 8.158e-13
37 NEURON PROJECTION MORPHOGENESIS 72 402 6.432e-15 8.158e-13
38 POSITIVE REGULATION OF CELL COMMUNICATION 179 1532 1.457e-14 1.784e-12
39 GROWTH 72 410 1.826e-14 2.179e-12
40 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 189 1656 2.314e-14 2.692e-12
41 DEVELOPMENTAL GROWTH 63 333 2.428e-14 2.756e-12
42 REGULATION OF CELL PROLIFERATION 175 1496 2.708e-14 3e-12
43 EMBRYONIC MORPHOGENESIS 85 539 4.669e-14 5.052e-12
44 NEURON DEVELOPMENT 100 687 4.786e-14 5.061e-12
45 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 161 1360 1.246e-13 1.26e-11
46 ANGIOGENESIS 57 293 1.238e-13 1.26e-11
47 EXTRACELLULAR STRUCTURE ORGANIZATION 58 304 1.803e-13 1.785e-11
48 RESPONSE TO ENDOGENOUS STIMULUS 168 1450 2.227e-13 2.159e-11
49 NEURON PROJECTION DEVELOPMENT 84 545 2.415e-13 2.293e-11
50 EMBRYO DEVELOPMENT 118 894 2.571e-13 2.392e-11
51 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 49 232 2.652e-13 2.419e-11
52 CELL PROJECTION ORGANIZATION 118 902 4.751e-13 4.251e-11
53 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 123 957 5.121e-13 4.496e-11
54 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 125 983 6.962e-13 5.999e-11
55 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 108 801 7.274e-13 6.154e-11
56 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 64 368 8.368e-13 6.953e-11
57 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 127 1008 8.68e-13 7.085e-11
58 NEGATIVE REGULATION OF CELL DIFFERENTIATION 89 609 1.006e-12 8.073e-11
59 MODULATION OF SYNAPTIC TRANSMISSION 56 301 1.384e-12 1.092e-10
60 POSITIVE REGULATION OF CELL PROLIFERATION 108 814 2.039e-12 1.582e-10
61 POSITIVE REGULATION OF NEURON DIFFERENTIATION 56 306 2.773e-12 2.115e-10
62 CELL MOTILITY 109 835 4.503e-12 3.325e-10
63 LOCALIZATION OF CELL 109 835 4.503e-12 3.325e-10
64 BEHAVIOR 78 516 4.832e-12 3.513e-10
65 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 59 337 4.96e-12 3.551e-10
66 REGULATION OF PHOSPHORUS METABOLIC PROCESS 177 1618 7.222e-12 5.091e-10
67 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 46 229 9.083e-12 6.308e-10
68 POSITIVE REGULATION OF GENE EXPRESSION 186 1733 1.029e-11 7.043e-10
69 NEGATIVE REGULATION OF CELL COMMUNICATION 140 1192 1.065e-11 7.183e-10
70 HEAD DEVELOPMENT 96 709 1.157e-11 7.69e-10
71 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 195 1848 1.366e-11 8.952e-10
72 REGULATION OF AXONOGENESIS 38 168 1.445e-11 9.336e-10
73 REGULATION OF EPITHELIAL CELL PROLIFERATION 52 285 1.88e-11 1.198e-09
74 CELL PART MORPHOGENESIS 88 633 2.124e-11 1.335e-09
75 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 125 1036 2.576e-11 1.557e-09
76 TAXIS 71 464 2.531e-11 1.557e-09
77 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 125 1036 2.576e-11 1.557e-09
78 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 93 689 2.931e-11 1.748e-09
79 UROGENITAL SYSTEM DEVELOPMENT 53 299 3.741e-11 2.203e-09
80 REGULATION OF TRANSPORT 189 1804 5.533e-11 3.218e-09
81 TISSUE MORPHOGENESIS 77 533 6.287e-11 3.568e-09
82 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 53 303 6.258e-11 3.568e-09
83 MUSCLE STRUCTURE DEVELOPMENT 66 432 1.376e-10 7.709e-09
84 CENTRAL NERVOUS SYSTEM DEVELOPMENT 108 872 1.392e-10 7.709e-09
85 SYNAPSE ORGANIZATION 33 145 2.644e-10 1.447e-08
86 SINGLE ORGANISM BEHAVIOR 60 384 3.889e-10 2.104e-08
87 RESPONSE TO GROWTH FACTOR 69 475 4.959e-10 2.652e-08
88 NEURON PROJECTION GUIDANCE 40 205 5.1e-10 2.697e-08
89 REGULATION OF SYSTEM PROCESS 72 507 5.762e-10 3.013e-08
90 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 43 232 6.262e-10 3.238e-08
91 POSITIVE REGULATION OF LOCOMOTION 63 420 7.738e-10 3.957e-08
92 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 92 724 9.347e-10 4.727e-08
93 REGULATION OF PROTEIN MODIFICATION PROCESS 176 1710 1.135e-09 5.677e-08
94 CONNECTIVE TISSUE DEVELOPMENT 38 194 1.227e-09 6.074e-08
95 SECRETION BY CELL 69 486 1.337e-09 6.55e-08
96 NEGATIVE REGULATION OF CELL PROLIFERATION 84 643 1.373e-09 6.657e-08
97 POSITIVE REGULATION OF MOLECULAR FUNCTION 182 1791 1.533e-09 7.355e-08
98 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 183 1805 1.642e-09 7.796e-08
99 EPITHELIUM DEVELOPMENT 111 945 1.731e-09 8.137e-08
100 MORPHOGENESIS OF AN EPITHELIUM 60 400 1.965e-09 9.013e-08
101 RESPONSE TO OXYGEN CONTAINING COMPOUND 148 1381 1.976e-09 9.013e-08
102 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 181 1784 1.939e-09 9.013e-08
103 REGULATION OF CELL ADHESION 82 629 2.393e-09 1.081e-07
104 SENSORY ORGAN DEVELOPMENT 69 493 2.461e-09 1.101e-07
105 REGULATION OF CELL DEATH 155 1472 2.699e-09 1.196e-07
106 REGULATION OF DEVELOPMENTAL GROWTH 48 289 2.948e-09 1.294e-07
107 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 97 799 3.621e-09 1.575e-07
108 TUBE DEVELOPMENT 74 552 4.395e-09 1.893e-07
109 NEGATIVE REGULATION OF CELL DEVELOPMENT 49 303 5.016e-09 2.141e-07
110 SECRETION 77 588 6.09e-09 2.576e-07
111 ACTION POTENTIAL 24 94 6.389e-09 2.678e-07
112 CARTILAGE DEVELOPMENT 31 147 6.511e-09 2.694e-07
113 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 103 876 6.542e-09 2.694e-07
114 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 114 1004 7.226e-09 2.949e-07
115 POSITIVE REGULATION OF CATALYTIC ACTIVITY 157 1518 7.32e-09 2.962e-07
116 BONE DEVELOPMENT 32 156 7.62e-09 3.03e-07
117 REGULATION OF SYNAPTIC PLASTICITY 30 140 7.684e-09 3.03e-07
118 OSSIFICATION 43 251 7.564e-09 3.03e-07
119 ORGAN GROWTH 20 68 8.364e-09 3.271e-07
120 MEMBRANE DEPOLARIZATION DURING ACTION POTENTIAL 15 39 1.021e-08 3.958e-07
121 NEGATIVE REGULATION OF LOCOMOTION 44 263 1.066e-08 4.099e-07
122 REGULATION OF CELL GROWTH 57 391 1.418e-08 5.407e-07
123 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 124 1135 1.509e-08 5.707e-07
124 RESPONSE TO ALCOHOL 54 362 1.532e-08 5.748e-07
125 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 153 1492 2.051e-08 7.636e-07
126 PROTEIN PHOSPHORYLATION 107 944 2.359e-08 8.712e-07
127 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 37 207 2.644e-08 9.686e-07
128 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 43 262 2.786e-08 1.013e-06
129 REGULATION OF KINASE ACTIVITY 92 776 2.933e-08 1.05e-06
130 REGULATION OF CELL SUBSTRATE ADHESION 33 173 2.93e-08 1.05e-06
131 REGULATION OF GROWTH 79 633 3.275e-08 1.163e-06
132 CELL CELL SIGNALING 91 767 3.377e-08 1.19e-06
133 MEMBRANE DEPOLARIZATION DURING CARDIAC MUSCLE CELL ACTION POTENTIAL 9 14 3.445e-08 1.205e-06
134 NEURON MIGRATION 25 110 3.921e-08 1.361e-06
135 RESPONSE TO ABIOTIC STIMULUS 113 1024 4.027e-08 1.388e-06
136 IMMUNE SYSTEM DEVELOPMENT 74 582 4.179e-08 1.43e-06
137 POSITIVE REGULATION OF CELL DEATH 76 605 4.562e-08 1.55e-06
138 EMBRYONIC ORGAN DEVELOPMENT 57 406 5.426e-08 1.829e-06
139 EYE DEVELOPMENT 49 326 5.549e-08 1.857e-06
140 APPENDAGE DEVELOPMENT 32 169 5.667e-08 1.87e-06
141 LIMB DEVELOPMENT 32 169 5.667e-08 1.87e-06
142 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 123 1152 6.382e-08 2.091e-06
143 POSITIVE REGULATION OF HYDROLASE ACTIVITY 102 905 6.767e-08 2.202e-06
144 REGULATION OF SYNAPSE ORGANIZATION 25 113 6.905e-08 2.231e-06
145 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 30 154 7.562e-08 2.427e-06
146 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 19 70 8.261e-08 2.633e-06
147 REGULATION OF ION TRANSPORT 74 592 8.41e-08 2.662e-06
148 LOCOMOTORY BEHAVIOR 33 181 9.077e-08 2.854e-06
149 MESENCHYME DEVELOPMENT 34 190 9.329e-08 2.894e-06
150 STEM CELL DIFFERENTIATION 34 190 9.329e-08 2.894e-06
151 REGULATION OF MAPK CASCADE 80 660 9.451e-08 2.912e-06
152 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 34 191 1.064e-07 3.236e-06
153 REGULATION OF GTPASE ACTIVITY 81 673 1.063e-07 3.236e-06
154 SKELETAL SYSTEM MORPHOGENESIS 35 201 1.221e-07 3.688e-06
155 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 31 166 1.261e-07 3.786e-06
156 RESPONSE TO ORGANIC CYCLIC COMPOUND 102 917 1.295e-07 3.863e-06
157 REGULATION OF EXTENT OF CELL GROWTH 23 101 1.307e-07 3.873e-06
158 REGULATION OF CELLULAR LOCALIZATION 132 1277 1.346e-07 3.964e-06
159 REGULATION OF HYDROLASE ACTIVITY 136 1327 1.408e-07 4.121e-06
160 MUSCLE ORGAN DEVELOPMENT 43 277 1.428e-07 4.152e-06
161 MORPHOGENESIS OF A BRANCHING STRUCTURE 31 167 1.452e-07 4.198e-06
162 FOREBRAIN DEVELOPMENT 51 357 1.56e-07 4.481e-06
163 RHYTHMIC PROCESS 45 298 1.674e-07 4.779e-06
164 REGULATION OF OSSIFICATION 32 178 1.979e-07 5.616e-06
165 EXOCYTOSIS 46 310 2.065e-07 5.824e-06
166 REGULATION OF RESPONSE TO WOUNDING 56 413 2.309e-07 6.433e-06
167 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 23 104 2.304e-07 6.433e-06
168 RESPONSE TO HORMONE 99 893 2.338e-07 6.459e-06
169 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 64 498 2.346e-07 6.459e-06
170 REGULATION OF CHEMOTAXIS 32 180 2.578e-07 7.055e-06
171 MEMBRANE DEPOLARIZATION 17 61 2.6e-07 7.074e-06
172 REGULATION OF MEMBRANE POTENTIAL 49 343 2.721e-07 7.361e-06
173 ODONTOGENESIS 23 105 2.767e-07 7.443e-06
174 RESPONSE TO EXTERNAL STIMULUS 174 1821 2.808e-07 7.51e-06
175 REGULATION OF TRANSMEMBRANE TRANSPORT 57 426 2.826e-07 7.513e-06
176 MUSCLE TISSUE DEVELOPMENT 42 275 3.132e-07 8.281e-06
177 REGULATION OF BLOOD CIRCULATION 44 295 3.263e-07 8.577e-06
178 REGULATION OF METAL ION TRANSPORT 47 325 3.306e-07 8.642e-06
179 POSITIVE REGULATION OF AXONOGENESIS 18 69 3.468e-07 9.016e-06
180 REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 15 50 4.581e-07 1.184e-05
181 PALATE DEVELOPMENT 20 85 4.856e-07 1.248e-05
182 COLLAGEN FIBRIL ORGANIZATION 13 38 4.896e-07 1.252e-05
183 KIDNEY EPITHELIUM DEVELOPMENT 25 125 5.376e-07 1.367e-05
184 MESENCHYMAL CELL DIFFERENTIATION 26 134 5.949e-07 1.504e-05
185 SECOND MESSENGER MEDIATED SIGNALING 29 160 6.111e-07 1.537e-05
186 REGULATED EXOCYTOSIS 36 224 6.217e-07 1.555e-05
187 EMBRYONIC DIGESTIVE TRACT DEVELOPMENT 12 33 6.332e-07 1.576e-05
188 POSITIVE REGULATION OF SYNAPTIC TRANSMISSION 23 110 6.665e-07 1.65e-05
189 TUBE MORPHOGENESIS 46 323 6.848e-07 1.686e-05
190 NEGATIVE CHEMOTAXIS 13 39 6.901e-07 1.69e-05
191 POSITIVE REGULATION OF MAPK CASCADE 60 470 6.983e-07 1.701e-05
192 POSITIVE REGULATION OF KINASE ACTIVITY 61 482 7.593e-07 1.831e-05
193 REGULATION OF HEMOPOIESIS 45 314 7.563e-07 1.831e-05
194 CELLULAR RESPONSE TO NITROGEN COMPOUND 63 505 8.26e-07 1.981e-05
195 REGULATION OF CHONDROCYTE DIFFERENTIATION 14 46 9.092e-07 2.158e-05
196 MUSCLE CELL DIFFERENTIATION 37 237 9.046e-07 2.158e-05
197 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 43 296 9.16e-07 2.163e-05
198 RESPONSE TO STEROID HORMONE 62 497 1.01e-06 2.373e-05
199 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 15 53 1.054e-06 2.451e-05
200 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 24 121 1.055e-06 2.451e-05
201 RESPONSE TO MECHANICAL STIMULUS 34 210 1.063e-06 2.451e-05
202 POST EMBRYONIC DEVELOPMENT 20 89 1.064e-06 2.451e-05
203 RESPONSE TO LIPID 96 888 1.11e-06 2.543e-05
204 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 28 156 1.164e-06 2.655e-05
205 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 24 122 1.232e-06 2.797e-05
206 MESONEPHROS DEVELOPMENT 20 90 1.284e-06 2.9e-05
207 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 21 98 1.323e-06 2.974e-05
208 REGULATION OF EPITHELIAL CELL MIGRATION 29 166 1.342e-06 3.003e-05
209 SINGLE ORGANISM CELL ADHESION 58 459 1.487e-06 3.31e-05
210 NEGATIVE REGULATION OF CELL ADHESION 35 223 1.56e-06 3.455e-05
211 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 25 133 1.795e-06 3.959e-05
212 CIRCULATORY SYSTEM PROCESS 49 366 1.877e-06 4.12e-05
213 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 40 274 1.92e-06 4.194e-05
214 REGULATION OF NEURONAL SYNAPTIC PLASTICITY 14 49 2.123e-06 4.615e-05
215 REGULATION OF CARTILAGE DEVELOPMENT 16 63 2.272e-06 4.918e-05
216 CELL FATE COMMITMENT 35 227 2.367e-06 5.1e-05
217 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 26 144 2.473e-06 5.302e-05
218 CARDIAC MUSCLE CELL ACTION POTENTIAL 12 37 2.582e-06 5.51e-05
219 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 21 102 2.622e-06 5.571e-05
220 REGULATION OF CALCIUM ION TRANSPORT 33 209 2.686e-06 5.646e-05
221 SYNAPTIC SIGNALING 54 424 2.678e-06 5.646e-05
222 POSITIVE REGULATION OF GROWTH 36 238 2.694e-06 5.646e-05
223 RESPONSE TO NITROGEN COMPOUND 92 859 2.765e-06 5.732e-05
224 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 40 278 2.772e-06 5.732e-05
225 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 14 50 2.77e-06 5.732e-05
226 BONE MORPHOGENESIS 18 79 2.947e-06 6.067e-05
227 ENDOTHELIAL CELL DIFFERENTIATION 17 72 3.284e-06 6.732e-05
228 REGULATION OF NEURON APOPTOTIC PROCESS 31 192 3.321e-06 6.777e-05
229 REGULATION OF ANATOMICAL STRUCTURE SIZE 58 472 3.611e-06 7.336e-05
230 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 97 926 3.846e-06 7.781e-05
231 RESPONSE TO WOUNDING 66 563 3.987e-06 7.997e-05
232 REGULATION OF ORGAN MORPHOGENESIS 36 242 3.984e-06 7.997e-05
233 REGULATION OF STEM CELL DIFFERENTIATION 22 113 4.044e-06 8.076e-05
234 CELL DEATH 103 1001 4.241e-06 8.433e-05
235 ENDOCHONDRAL BONE MORPHOGENESIS 13 45 4.273e-06 8.461e-05
236 REGULATION OF VASCULATURE DEVELOPMENT 35 233 4.325e-06 8.526e-05
237 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 65 554 4.582e-06 8.996e-05
238 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 57 465 4.713e-06 9.215e-05
239 MULTICELLULAR ORGANISMAL SIGNALING 23 123 5.032e-06 9.796e-05
240 NEGATIVE REGULATION OF CELL DEATH 92 872 5.135e-06 9.955e-05
241 ENDOTHELIUM DEVELOPMENT 19 90 5.27e-06 0.0001017
242 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 22 115 5.458e-06 0.0001049
243 NEURAL CREST CELL DIFFERENTIATION 17 75 5.951e-06 0.000114
244 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 20 99 6.108e-06 0.000116
245 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 20 99 6.108e-06 0.000116
246 REGULATION OF HOMEOSTATIC PROCESS 55 447 6.163e-06 0.0001166
247 CAMP METABOLIC PROCESS 11 34 6.956e-06 0.000131
248 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 20 100 7.167e-06 0.0001345
249 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 22 117 7.306e-06 0.0001365
250 EMBRYONIC ORGAN MORPHOGENESIS 39 279 7.414e-06 0.0001377
251 POSITIVE REGULATION OF OSSIFICATION 18 84 7.428e-06 0.0001377
252 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 27 162 7.656e-06 0.0001414
253 REGULATION OF CELL ACTIVATION 58 484 7.834e-06 0.0001441
254 CELLULAR RESPONSE TO HORMONE STIMULUS 64 552 7.971e-06 0.000146
255 RESPONSE TO OXYGEN LEVELS 42 311 8.047e-06 0.0001468
256 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 63 541 8.148e-06 0.0001475
257 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 63 541 8.148e-06 0.0001475
258 REGULATION OF CELL SIZE 28 172 8.301e-06 0.0001497
259 REGULATION OF HEART CONTRACTION 33 221 9.14e-06 0.0001642
260 COGNITION 36 251 9.222e-06 0.000165
261 REGULATION OF POSTSYNAPTIC MEMBRANE POTENTIAL 14 55 9.418e-06 0.0001673
262 CRANIAL SKELETAL SYSTEM DEVELOPMENT 14 55 9.418e-06 0.0001673
263 REGULATION OF LEUKOCYTE DIFFERENTIATION 34 232 1.015e-05 0.0001796
264 CELL ACTIVATION 65 568 1.037e-05 0.0001827
265 REGULATION OF MUSCLE TISSUE DEVELOPMENT 20 103 1.141e-05 0.0002004
266 REGULATION OF SYNAPSE ASSEMBLY 17 79 1.247e-05 0.0002181
267 POSITIVE REGULATION OF CELL GROWTH 25 148 1.293e-05 0.0002245
268 POSITIVE REGULATION OF AXON EXTENSION 11 36 1.292e-05 0.0002245
269 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 56 470 1.323e-05 0.0002288
270 CYCLIC NUCLEOTIDE METABOLIC PROCESS 14 57 1.47e-05 0.0002524
271 OVULATION CYCLE PROCESS 18 88 1.469e-05 0.0002524
272 REGULATION OF ENDOTHELIAL CELL MIGRATION 21 114 1.625e-05 0.0002779
273 CELL COMMUNICATION INVOLVED IN CARDIAC CONDUCTION 11 37 1.73e-05 0.0002948
274 POSITIVE REGULATION OF TRANSPORT 95 936 1.747e-05 0.0002966
275 TELENCEPHALON DEVELOPMENT 33 228 1.771e-05 0.0002996
276 NEPHRON DEVELOPMENT 21 115 1.866e-05 0.0003145
277 REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION 10 31 1.88e-05 0.0003158
278 REGULATION OF CELL MATRIX ADHESION 18 90 2.029e-05 0.0003396
279 REGULATION OF HEAT GENERATION 7 15 2.168e-05 0.0003616
280 EMBRYONIC HEMOPOIESIS 8 20 2.18e-05 0.0003623
281 CELLULAR RESPONSE TO LIPID 54 457 2.37e-05 0.0003905
282 ENSHEATHMENT OF NEURONS 18 91 2.375e-05 0.0003905
283 AXON ENSHEATHMENT 18 91 2.375e-05 0.0003905
284 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 15 67 2.432e-05 0.0003984
285 NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS 23 135 2.458e-05 0.0003984
286 REGULATION OF NEURON DEATH 35 252 2.455e-05 0.0003984
287 CELL GROWTH 23 135 2.458e-05 0.0003984
288 PROTEOGLYCAN METABOLIC PROCESS 17 83 2.473e-05 0.0003996
289 POSITIVE REGULATION OF HEMOPOIESIS 26 163 2.483e-05 0.0003998
290 POSITIVE REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION 9 26 2.602e-05 0.0004175
291 REGULATION OF INTRACELLULAR TRANSPORT 68 621 2.758e-05 0.0004409
292 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 15 68 2.931e-05 0.0004671
293 POSITIVE REGULATION OF PHOSPHOLIPASE ACTIVITY 13 53 3.001e-05 0.0004749
294 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 28 184 2.991e-05 0.0004749
295 EMBRYONIC CRANIAL SKELETON MORPHOGENESIS 12 46 3.114e-05 0.0004911
296 SKELETAL MUSCLE ORGAN DEVELOPMENT 23 137 3.131e-05 0.0004922
297 REGULATION OF CELLULAR COMPONENT BIOGENESIS 80 767 3.177e-05 0.0004977
298 EMBRYONIC SKELETAL SYSTEM MORPHOGENESIS 18 93 3.229e-05 0.0005042
299 CHONDROCYTE DEVELOPMENT 8 21 3.318e-05 0.0005146
300 CELL PROLIFERATION 72 672 3.316e-05 0.0005146
301 REGULATION OF MUSCLE SYSTEM PROCESS 29 195 3.364e-05 0.0005184
302 POSITIVE REGULATION OF STEM CELL PROLIFERATION 14 61 3.354e-05 0.0005184
303 CARDIAC SEPTUM DEVELOPMENT 17 85 3.419e-05 0.0005216
304 HEART PROCESS 17 85 3.419e-05 0.0005216
305 PATTERN SPECIFICATION PROCESS 50 418 3.41e-05 0.0005216
306 REGULATION OF PEPTIDE TRANSPORT 35 256 3.432e-05 0.0005219
307 DEVELOPMENTAL CELL GROWTH 16 77 3.528e-05 0.0005347
308 CYTOKINE PRODUCTION 21 120 3.623e-05 0.0005474
309 REGULATION OF WNT SIGNALING PATHWAY 40 310 3.794e-05 0.0005713
310 REGULATION OF CALCIUM ION IMPORT 19 103 3.97e-05 0.0005921
311 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 19 103 3.97e-05 0.0005921
312 REGULATION OF MUSCLE ORGAN DEVELOPMENT 19 103 3.97e-05 0.0005921
313 POSITIVE REGULATION OF CELL ADHESION 46 376 3.989e-05 0.000593
314 REGULATION OF SMOOTHENED SIGNALING PATHWAY 14 62 4.072e-05 0.0006019
315 REGULATION OF OSTEOBLAST DIFFERENTIATION 20 112 4.087e-05 0.0006019
316 RESPIRATORY SYSTEM DEVELOPMENT 29 197 4.075e-05 0.0006019
317 METAL ION TRANSPORT 64 582 4.151e-05 0.0006093
318 REGULATION OF TRANSFERASE ACTIVITY 94 946 4.369e-05 0.0006392
319 REGULATION OF ACTIN FILAMENT BASED PROCESS 40 312 4.392e-05 0.0006406
320 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 22 131 4.591e-05 0.0006676
321 OVULATION CYCLE 20 113 4.663e-05 0.0006759
322 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 77 740 4.826e-05 0.0006974
323 LEUKOCYTE DIFFERENTIATION 38 292 4.873e-05 0.0007019
324 IMMUNE SYSTEM PROCESS 174 1984 4.905e-05 0.0007034
325 CELL CELL SIGNALING INVOLVED IN CARDIAC CONDUCTION 8 22 4.913e-05 0.0007034
326 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 12 48 4.93e-05 0.0007037
327 RIBONUCLEOTIDE CATABOLIC PROCESS 9 28 5.1e-05 0.0007251
328 MUSCLE SYSTEM PROCESS 37 282 5.112e-05 0.0007251
329 REGULATION OF LYMPHOCYTE DIFFERENTIATION 22 132 5.172e-05 0.0007314
330 CARTILAGE MORPHOGENESIS 6 12 5.365e-05 0.0007565
331 REGULATION OF CELLULAR COMPONENT SIZE 42 337 5.553e-05 0.0007807
332 NEGATIVE REGULATION OF NEURON DEATH 26 171 5.754e-05 0.0008064
333 CYCLIC NUCLEOTIDE CATABOLIC PROCESS 7 17 5.827e-05 0.0008142
334 REGULATION OF PHOSPHOLIPASE ACTIVITY 14 64 5.92e-05 0.0008247
335 INOSITOL LIPID MEDIATED SIGNALING 21 124 5.971e-05 0.0008293
336 NEGATIVE REGULATION OF PROTEIN PROCESSING 10 35 6.104e-05 0.0008427
337 NEGATIVE REGULATION OF PROTEIN MATURATION 10 35 6.104e-05 0.0008427
338 POSITIVE REGULATION OF RESPONSE TO WOUNDING 25 162 6.185e-05 0.0008515
339 NEGATIVE REGULATION OF GENE EXPRESSION 136 1493 6.562e-05 0.0009007
340 REGULATION OF SECRETION 73 699 6.717e-05 0.0009192
341 FEMALE SEX DIFFERENTIATION 20 116 6.846e-05 0.0009341
342 CARDIAC CHAMBER DEVELOPMENT 23 144 6.989e-05 0.0009498
343 MULTI MULTICELLULAR ORGANISM PROCESS 30 213 7.002e-05 0.0009498
344 NEGATIVE REGULATION OF AXONOGENESIS 14 65 7.091e-05 0.0009591
345 REGULATION OF MAP KINASE ACTIVITY 40 319 7.222e-05 0.000974
346 CELL CYCLE ARREST 24 154 7.34e-05 0.0009826
347 CALCIUM MEDIATED SIGNALING 17 90 7.314e-05 0.0009826
348 REPRODUCTIVE SYSTEM DEVELOPMENT 48 408 7.349e-05 0.0009826
349 OSTEOBLAST DIFFERENTIATION 21 126 7.59e-05 0.001012
350 KIDNEY MORPHOGENESIS 16 82 7.882e-05 0.001045
351 CARDIAC CONDUCTION 16 82 7.882e-05 0.001045
352 NEGATIVE REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 14 66 8.459e-05 0.001112
353 FOREBRAIN GENERATION OF NEURONS 14 66 8.459e-05 0.001112
354 NEGATIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 14 66 8.459e-05 0.001112
355 CELL JUNCTION ORGANIZATION 27 185 8.595e-05 0.001127
356 POSITIVE REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 7 18 8.992e-05 0.001172
357 INOSITOL PHOSPHATE MEDIATED SIGNALING 7 18 8.992e-05 0.001172
358 ACTIVATION OF PROTEIN KINASE ACTIVITY 36 279 9.076e-05 0.00118
359 NEGATIVE REGULATION OF CHEMOTAXIS 12 51 9.344e-05 0.001211
360 LAMELLIPODIUM ASSEMBLY 9 30 9.368e-05 0.001211
361 MUSCLE CELL DEVELOPMENT 21 128 9.588e-05 0.001236
362 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL 15 75 9.744e-05 0.001252
363 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 86 867 9.779e-05 0.001254
364 REGULATION OF POSITIVE CHEMOTAXIS 8 24 0.0001003 0.001279
365 REGULATION OF LONG TERM NEURONAL SYNAPTIC PLASTICITY 8 24 0.0001003 0.001279
366 CORONARY VASCULATURE DEVELOPMENT 10 37 0.0001026 0.001304
367 DIGESTIVE SYSTEM DEVELOPMENT 23 148 0.0001074 0.001362
368 REGULATION OF CATION TRANSMEMBRANE TRANSPORT 29 208 0.0001101 0.001392
369 POSITIVE REGULATION OF CHEMOTAXIS 20 120 0.0001115 0.001405
370 REGULATION OF TRANSPORTER ACTIVITY 28 198 0.0001121 0.00141
371 REGULATION OF CALCIUM MEDIATED SIGNALING 15 76 0.0001141 0.001427
372 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 47 404 0.0001138 0.001427
373 REGULATION OF CELL JUNCTION ASSEMBLY 14 68 0.000119 0.00148
374 CHONDROCYTE DIFFERENTIATION 13 60 0.0001196 0.00148
375 MATERNAL PROCESS INVOLVED IN FEMALE PREGNANCY 13 60 0.0001196 0.00148
376 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 13 60 0.0001196 0.00148
377 REGULATION OF INFLAMMATORY RESPONSE 37 294 0.0001229 0.001517
378 GLAND DEVELOPMENT 46 395 0.0001308 0.00161
379 POSITIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 21 131 0.0001346 0.001653
380 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 27 190 0.0001357 0.001662
381 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 12 53 0.0001389 0.00168
382 WNT SIGNALING PATHWAY 42 351 0.0001394 0.00168
383 CELLULAR EXTRAVASATION 8 25 0.000139 0.00168
384 MESONEPHRIC TUBULE MORPHOGENESIS 12 53 0.0001389 0.00168
385 SKELETAL MUSCLE CELL DIFFERENTIATION 12 53 0.0001389 0.00168
386 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL BY SARCOPLASMIC RETICULUM 8 25 0.000139 0.00168
387 REGULATION OF ION HOMEOSTASIS 28 201 0.0001456 0.001751
388 HEART MORPHOGENESIS 29 212 0.0001544 0.001851
389 CAMP CATABOLIC PROCESS 6 14 0.0001554 0.001859
390 NEGATIVE REGULATION OF CELL CYCLE 49 433 0.0001616 0.001929
391 POSITIVE REGULATION OF ENDOCYTOSIS 19 114 0.0001638 0.001949
392 REGULATION OF AXON GUIDANCE 10 39 0.0001659 0.001964
393 NEGATIVE REGULATION OF PHOSPHORYLATION 48 422 0.0001663 0.001964
394 POSITIVE REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 10 39 0.0001659 0.001964
395 REGULATION OF CYTOPLASMIC TRANSPORT 53 481 0.0001757 0.00207
396 DEVELOPMENTAL MATURATION 27 193 0.0001767 0.002077
397 STRIATED MUSCLE CELL DIFFERENTIATION 25 173 0.0001812 0.002123
398 REGULATION OF FAT CELL DIFFERENTIATION 18 106 0.0001893 0.002191
399 REPLACEMENT OSSIFICATION 8 26 0.0001893 0.002191
400 REGULATION OF STEM CELL PROLIFERATION 16 88 0.0001881 0.002191
401 ENDOCHONDRAL OSSIFICATION 8 26 0.0001893 0.002191
402 PHOSPHORYLATION 113 1228 0.0001875 0.002191
403 LYMPH VESSEL DEVELOPMENT 7 20 0.0001948 0.002244
404 MELANOCYTE DIFFERENTIATION 7 20 0.0001948 0.002244
405 AMEBOIDAL TYPE CELL MIGRATION 23 154 0.0001974 0.002263
406 EPITHELIAL CELL DIFFERENTIATION 54 495 0.0001975 0.002263
407 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 19 116 0.000207 0.002355
408 RESPONSE TO FIBROBLAST GROWTH FACTOR 19 116 0.000207 0.002355
409 REGULATION OF CELL CELL ADHESION 44 380 0.0002061 0.002355
410 DEVELOPMENTAL PIGMENTATION 10 40 0.0002082 0.002363
411 REGULATION OF SEQUESTERING OF CALCIUM ION 18 107 0.0002138 0.002411
412 ADENYLATE CYCLASE MODULATING G PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY 22 145 0.000214 0.002411
413 PLATELET DEGRANULATION 18 107 0.0002138 0.002411
414 EPITHELIAL CELL PROLIFERATION 16 89 0.0002155 0.002422
415 ACTIN FILAMENT BASED PROCESS 50 450 0.000217 0.002433
416 NEUROTRANSMITTER TRANSPORT 23 155 0.0002176 0.002433
417 REGULATION OF WOUND HEALING 20 126 0.0002206 0.002461
418 LEUKOCYTE MIGRATION 33 259 0.0002216 0.002467
419 REGULATION OF RECEPTOR ACTIVITY 19 117 0.0002321 0.002577
420 EPITHELIAL CELL DEVELOPMENT 26 186 0.0002339 0.002591
421 REGULATION OF NEUROTRANSMITTER TRANSPORT 13 64 0.0002378 0.002628
422 AMINOGLYCAN METABOLIC PROCESS 24 166 0.0002398 0.002645
423 ION TRANSPORT 115 1262 0.0002413 0.002648
424 MUCOPOLYSACCHARIDE METABOLIC PROCESS 18 108 0.000241 0.002648
425 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 12 56 0.0002419 0.002649
426 CELL COMMUNICATION BY ELECTRICAL COUPLING 6 15 0.0002446 0.002671
427 REGULATION OF GLIOGENESIS 16 90 0.0002462 0.002683
428 HIPPO SIGNALING 8 27 0.0002535 0.002737
429 CALCIUM DEPENDENT CELL CELL ADHESION VIA PLASMA MEMBRANE CELL ADHESION MOLECULES 8 27 0.0002535 0.002737
430 REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 8 27 0.0002535 0.002737
431 CENTRAL NERVOUS SYSTEM NEURON AXONOGENESIS 8 27 0.0002535 0.002737
432 REGULATION OF ORGAN GROWTH 14 73 0.000262 0.002822
433 FOREBRAIN NEURON DEVELOPMENT 9 34 0.0002702 0.002904
434 SYMPATHETIC NERVOUS SYSTEM DEVELOPMENT 7 21 0.0002757 0.002949
435 LIPID TRANSLOCATION 7 21 0.0002757 0.002949
436 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 21 138 0.0002829 0.003011
437 PHOSPHATIDYLINOSITOL 3 PHOSPHATE BIOSYNTHETIC PROCESS 11 49 0.0002834 0.003011
438 LYMPHOCYTE DIFFERENTIATION 28 209 0.0002826 0.003011
439 MYELOID CELL DIFFERENTIATION 26 189 0.0003022 0.003203
440 REGULATION OF CELL SHAPE 21 139 0.0003129 0.003309
441 REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 16 92 0.0003194 0.003365
442 POSITIVE REGULATION OF GLUCOSE TRANSPORT 10 42 0.0003203 0.003365
443 AUTONOMIC NERVOUS SYSTEM DEVELOPMENT 10 42 0.0003203 0.003365
444 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 168 1977 0.0003252 0.003408
445 POSITIVE REGULATION OF LIPASE ACTIVITY 13 66 0.0003273 0.003414
446 LENS DEVELOPMENT IN CAMERA TYPE EYE 13 66 0.0003273 0.003414
447 REGULATION OF NEUROTRANSMITTER LEVELS 26 190 0.0003285 0.00342
448 REGULATION OF PROTEIN LOCALIZATION 90 950 0.0003298 0.003426
449 WOUND HEALING 51 470 0.0003331 0.003452
450 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 62 602 0.0003377 0.003492
451 DIVALENT INORGANIC CATION HOMEOSTASIS 40 343 0.0003391 0.003498
452 REGULATION OF ADHERENS JUNCTION ORGANIZATION 11 50 0.0003419 0.003512
453 PROTEOGLYCAN BIOSYNTHETIC PROCESS 12 58 0.0003419 0.003512
454 CARDIAC MUSCLE TISSUE DEVELOPMENT 21 140 0.0003456 0.003542
455 ARTERY DEVELOPMENT 14 75 0.0003512 0.003583
456 SENSORY PERCEPTION OF PAIN 14 75 0.0003512 0.003583
457 RESPONSE TO NUTRIENT 26 191 0.0003569 0.003634
458 ACTIN FILAMENT BASED MOVEMENT 16 93 0.0003625 0.003666
459 NEPHRON EPITHELIUM DEVELOPMENT 16 93 0.0003625 0.003666
460 SEX DIFFERENTIATION 33 266 0.0003622 0.003666
461 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 63 616 0.0003659 0.003693
462 CALCIUM ION TRANSPORT 29 223 0.0003685 0.003697
463 NEURON CELL CELL ADHESION 6 16 0.0003695 0.003697
464 RETINA VASCULATURE DEVELOPMENT IN CAMERA TYPE EYE 6 16 0.0003695 0.003697
465 POSITIVE REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 6 16 0.0003695 0.003697
466 IN UTERO EMBRYONIC DEVELOPMENT 37 311 0.0003786 0.003772
467 REGIONALIZATION 37 311 0.0003786 0.003772
468 CELLULAR RESPONSE TO DRUG 13 67 0.0003818 0.003796
469 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 19 122 0.0004016 0.003985
470 REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION 27 203 0.0004041 0.004
471 REGULATION OF NEUROTRANSMITTER SECRETION 11 51 0.0004103 0.004041
472 NEURAL CREST CELL MIGRATION 11 51 0.0004103 0.004041
473 REGULATION OF FEVER GENERATION 5 11 0.0004117 0.004041
474 LOCOMOTORY EXPLORATION BEHAVIOR 5 11 0.0004117 0.004041
475 RESPONSE TO PEPTIDE 45 404 0.0004155 0.00407
476 POSITIVE REGULATION OF INFLAMMATORY RESPONSE 18 113 0.000427 0.004174
477 NEGATIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 9 36 0.0004303 0.00418
478 LAMELLIPODIUM ORGANIZATION 9 36 0.0004303 0.00418
479 NEGATIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 9 36 0.0004303 0.00418
480 REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 8 29 0.0004354 0.004194
481 REGULATION OF MYELOID CELL DIFFERENTIATION 25 183 0.0004348 0.004194
482 PIGMENT CELL DIFFERENTIATION 8 29 0.0004354 0.004194
483 CARDIAC MUSCLE CELL CONTRACTION 8 29 0.0004354 0.004194
484 NERVE DEVELOPMENT 13 68 0.000444 0.004259
485 ADENYLATE CYCLASE INHIBITING G PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY 13 68 0.000444 0.004259
486 REGULATION OF GLUCOSE IMPORT 12 60 0.0004748 0.004536
487 REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 12 60 0.0004748 0.004536
488 CATION TRANSPORT 77 796 0.0004772 0.00455
489 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 42 372 0.0004824 0.00459
490 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 28 216 0.0004857 0.004612
491 ION TRANSMEMBRANE TRANSPORT 79 822 0.000492 0.004662
492 CELL SUBSTRATE ADHESION 23 164 0.0004982 0.004712
493 REGULATION OF OSTEOBLAST PROLIFERATION 7 23 0.0005172 0.004852
494 REGULATION OF RESPIRATORY GASEOUS EXCHANGE 7 23 0.0005172 0.004852
495 NEUROTROPHIN SIGNALING PATHWAY 7 23 0.0005172 0.004852
496 SYNAPSE ASSEMBLY 13 69 0.0005145 0.004852
497 CARDIOCYTE DIFFERENTIATION 16 96 0.0005231 0.004898
498 CELLULAR RESPONSE TO ALCOHOL 18 115 0.0005306 0.004957
499 RENAL TUBULE DEVELOPMENT 14 78 0.0005329 0.004966
500 ION HOMEOSTASIS 59 576 0.0005336 0.004966
501 SENSORY ORGAN MORPHOGENESIS 30 239 0.000539 0.005006
502 NEGATIVE REGULATION OF KINASE ACTIVITY 31 250 0.0005422 0.005025
503 REGULATION OF CELL PROJECTION ASSEMBLY 22 155 0.0005535 0.00512
504 OVARIAN FOLLICLE DEVELOPMENT 12 61 0.000556 0.005133
505 MEMBRANE BIOGENESIS 8 30 0.0005596 0.005156
506 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 28 218 0.0005635 0.005181
507 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 40 352 0.0005714 0.005244
508 RESPONSE TO CORTICOSTEROID 24 176 0.0005757 0.005273
509 ENDOTHELIAL CELL DEVELOPMENT 10 45 0.0005796 0.005281
510 SPROUTING ANGIOGENESIS 10 45 0.0005796 0.005281
511 REGULATION OF HORMONE SECRETION 32 262 0.00058 0.005281
512 GLAND MORPHOGENESIS 16 97 0.0005888 0.005351
513 MULTICELLULAR ORGANISMAL MACROMOLECULE METABOLIC PROCESS 14 79 0.000609 0.005523
514 RESPONSE TO ETHANOL 20 136 0.0006134 0.005553
515 REGULATION OF PEPTIDE SECRETION 27 209 0.0006401 0.005784
516 NEGATIVE REGULATION OF SYNAPTIC TRANSMISSION 12 62 0.0006487 0.005849
517 LIPID LOCALIZATION 32 264 0.0006615 0.005953
518 CELLULAR RESPONSE TO EPINEPHRINE STIMULUS 5 12 0.0006674 0.005995
519 REGULATION OF ENDOCYTOSIS 26 199 0.0006734 0.006037
520 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 47 437 0.0006785 0.006071
521 ENDODERM DEVELOPMENT 13 71 0.0006841 0.00611
522 LEUKOCYTE ACTIVATION 45 414 7e-04 0.00624
523 MATERNAL PLACENTA DEVELOPMENT 8 31 0.000711 0.006326
524 REGULATION OF VESICLE MEDIATED TRANSPORT 49 462 0.0007197 0.006391
525 ORGANELLE LOCALIZATION 45 415 0.0007363 0.006526
526 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 67 684 0.0007835 0.00693
527 POSITIVE REGULATION OF PROTEIN KINASE B SIGNALING 14 81 0.000789 0.006966
528 REGULATION OF PHOSPHOLIPASE C ACTIVITY 9 39 0.0008098 0.007137
529 POSITIVE REGULATION OF CYTOKINE PRODUCTION 41 370 0.0008123 0.007145
530 CELL JUNCTION ASSEMBLY 19 129 0.000814 0.007146
531 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 131 1517 0.0008259 0.007223
532 RESPONSE TO EXTRACELLULAR STIMULUS 47 441 0.0008248 0.007223
533 NEGATIVE REGULATION OF CELL GROWTH 23 170 0.000828 0.007228
534 POSITIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 16 100 0.0008295 0.007228
535 REGULATION OF CYTOKINE PRODUCTION 57 563 0.0008699 0.007565
536 PROXIMAL DISTAL PATTERN FORMATION 8 32 0.0008937 0.007723
537 REGULATION OF PROTEIN MATURATION 14 82 0.0008946 0.007723
538 NEGATIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 8 32 0.0008937 0.007723
539 REGULATION OF ACTIN FILAMENT BASED MOVEMENT 8 32 0.0008937 0.007723
540 MEMBRANE ASSEMBLY 7 25 0.0009026 0.007735
541 REGULATION OF TRANSFORMING GROWTH FACTOR BETA PRODUCTION 7 25 0.0009026 0.007735
542 REGULATION OF FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 7 25 0.0009026 0.007735
543 POSTSYNAPTIC MEMBRANE ORGANIZATION 7 25 0.0009026 0.007735
544 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 29 236 0.0009304 0.007958
545 SMAD PROTEIN SIGNAL TRANSDUCTION 11 56 0.0009472 0.008072
546 REGULATION OF DENDRITIC SPINE DEVELOPMENT 11 56 0.0009472 0.008072
547 REGULATION OF IMMUNE SYSTEM PROCESS 122 1403 0.0009665 0.008221
548 G PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY COUPLED TO CYCLIC NUCLEOTIDE SECOND MESSENGER 23 172 0.0009736 0.008267
549 HOMEOSTATIC PROCESS 117 1337 0.0009782 0.00829
550 LEARNING 19 131 0.000984 0.008324
551 DIGESTIVE TRACT MORPHOGENESIS 10 48 0.0009921 0.008378
552 CELL CHEMOTAXIS 22 162 0.001011 0.008514
553 REGULATION OF LIPASE ACTIVITY 14 83 0.001012 0.008514
554 REGULATION OF RESPIRATORY GASEOUS EXCHANGE BY NEUROLOGICAL SYSTEM PROCESS 5 13 0.001026 0.008554
555 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 13 74 0.001025 0.008554
556 REGULATION OF ACUTE INFLAMMATORY RESPONSE 13 74 0.001025 0.008554
557 CELLULAR RESPONSE TO ETHANOL 5 13 0.001026 0.008554
558 ACTIN MEDIATED CELL CONTRACTION 13 74 0.001025 0.008554
559 REGULATION OF BODY FLUID LEVELS 52 506 0.001032 0.008591
560 REGULATION OF MUSCLE CELL DIFFERENTIATION 21 152 0.001042 0.008659
561 NEGATIVE REGULATION OF TRANSPORT 48 458 0.001047 0.008683
562 REGULATION OF CARDIAC MUSCLE CONTRACTION BY REGULATION OF THE RELEASE OF SEQUESTERED CALCIUM ION 6 19 0.001054 0.00873
563 PHENOL CONTAINING COMPOUND BIOSYNTHETIC PROCESS 8 33 0.001112 0.009192
564 GLYCOPROTEIN METABOLIC PROCESS 39 353 0.001136 0.009372
565 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 14 84 0.001142 0.009404
566 ODONTOGENESIS OF DENTIN CONTAINING TOOTH 13 75 0.001167 0.009591
567 NEGATIVE REGULATION OF FAT CELL DIFFERENTIATION 9 41 0.001188 0.009753
568 CHEMICAL HOMEOSTASIS 81 874 0.001225 0.009981
569 RESPONSE TO ESTROGEN 27 218 0.001219 0.009981
570 RESPONSE TO BMP 15 94 0.001224 0.009981
571 CELLULAR RESPONSE TO BMP STIMULUS 15 94 0.001224 0.009981
NumGOOverlapSizeP ValueAdj. P Value
1 CALCIUM ION BINDING 100 697 1.198e-13 1.113e-10
2 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 90 629 2.493e-12 1.158e-09
3 CYTOSKELETAL PROTEIN BINDING 107 819 6.808e-12 2.108e-09
4 REGULATORY REGION NUCLEIC ACID BINDING 104 818 6.878e-11 1.278e-08
5 GROWTH FACTOR BINDING 31 123 5.858e-11 1.278e-08
6 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 55 328 1.442e-10 2.233e-08
7 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 53 315 2.743e-10 3.186e-08
8 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 43 226 2.658e-10 3.186e-08
9 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 135 1199 4.607e-10 4.755e-08
10 RECEPTOR BINDING 158 1476 5.683e-10 5.279e-08
11 MACROMOLECULAR COMPLEX BINDING 151 1399 8.074e-10 6.819e-08
12 PROTEIN COMPLEX BINDING 108 935 7.321e-09 5.668e-07
13 ACTIN BINDING 57 393 1.705e-08 1.218e-06
14 CALMODULIN BINDING 33 179 6.894e-08 4.575e-06
15 CELL ADHESION MOLECULE BINDING 32 186 5.536e-07 3.428e-05
16 DOUBLE STRANDED DNA BINDING 86 764 7.879e-07 4.403e-05
17 SEQUENCE SPECIFIC DNA BINDING 109 1037 8.056e-07 4.403e-05
18 CYTOKINE BINDING 20 92 1.853e-06 9.562e-05
19 MOLECULAR FUNCTION REGULATOR 132 1353 3.112e-06 0.0001521
20 HEPARIN BINDING 27 157 4.182e-06 0.0001942
21 METAL ION TRANSMEMBRANE TRANSPORTER ACTIVITY 52 417 7.499e-06 0.0003318
22 PROTEIN KINASE ACTIVITY 71 640 1.192e-05 0.0005033
23 CATION CHANNEL ACTIVITY 40 298 1.515e-05 0.0006119
24 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 17 81 1.767e-05 0.0006528
25 PASSIVE TRANSMEMBRANE TRANSPORTER ACTIVITY 55 464 1.827e-05 0.0006528
26 ENZYME BINDING 158 1737 1.737e-05 0.0006528
27 X3 5 CYCLIC AMP PHOSPHODIESTERASE ACTIVITY 7 15 2.168e-05 0.0006751
28 VOLTAGE GATED ION CHANNEL ACTIVITY 29 190 2.051e-05 0.0006751
29 VOLTAGE GATED SODIUM CHANNEL ACTIVITY 8 20 2.18e-05 0.0006751
30 CYTOKINE RECEPTOR BINDING 37 271 2.14e-05 0.0006751
31 CORE PROMOTER PROXIMAL REGION DNA BINDING 46 371 2.857e-05 0.0008561
32 KINASE ACTIVITY 86 842 3.485e-05 0.0009756
33 GLYCOSAMINOGLYCAN BINDING 30 205 3.39e-05 0.0009756
34 TRANSFORMING GROWTH FACTOR BETA BINDING 7 16 3.635e-05 0.0009756
35 CHEMOREPELLENT ACTIVITY 9 27 3.675e-05 0.0009756
36 METALLOENDOPEPTIDASE ACTIVITY 20 113 4.663e-05 0.001203
37 FIBRONECTIN BINDING 9 28 5.1e-05 0.001281
38 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II DISTAL ENHANCER SEQUENCE SPECIFIC BINDING 17 90 7.314e-05 0.001788
39 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 31 228 0.0001043 0.002422
40 PROTEIN DOMAIN SPECIFIC BINDING 66 624 0.0001024 0.002422
41 TUBULIN BINDING 35 273 0.0001284 0.002909
42 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE ACTIVITY 8 25 0.000139 0.003075
43 LIPID BINDING 68 657 0.000154 0.003326
44 INTEGRIN BINDING 18 105 0.0001673 0.003533
45 KINASE BINDING 63 606 0.0002354 0.004652
46 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 37 303 0.0002266 0.004652
47 IDENTICAL PROTEIN BINDING 111 1209 0.0002331 0.004652
48 E BOX BINDING 9 34 0.0002702 0.00523
49 COLLAGEN BINDING 13 65 0.0002795 0.005298
50 FIBROBLAST GROWTH FACTOR RECEPTOR BINDING 8 28 0.0003345 0.006215
51 MICROTUBULE BINDING 27 201 0.0003446 0.006277
52 X1 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 10 43 0.000393 0.007021
53 EXTRACELLULAR MATRIX STRUCTURAL CONSTITUENT 14 76 0.0004047 0.007083
54 HIGH VOLTAGE GATED CALCIUM CHANNEL ACTIVITY 5 11 0.0004117 0.007083
55 GATED CHANNEL ACTIVITY 38 325 0.0004478 0.00752
56 TRANSCRIPTION FACTOR BINDING 55 524 0.0004533 0.00752
57 ZINC ION BINDING 105 1155 0.0004881 0.007955
58 SODIUM CHANNEL ACTIVITY 9 37 0.0005357 0.00858
59 SCAFFOLD PROTEIN BINDING 10 45 0.0005796 0.009126
60 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 13 70 0.0005942 0.0092
61 SODIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 20 136 0.0006134 0.009341
NumGOOverlapSizeP ValueAdj. P Value
1 CELL PROJECTION 232 1786 6.052e-25 3.534e-22
2 NEURON PROJECTION 150 942 1.352e-24 3.949e-22
3 NEURON PART 178 1265 8.043e-23 1.566e-20
4 SYNAPSE 121 754 3.22e-20 4.701e-18
5 CELL JUNCTION 156 1151 1.925e-18 2.248e-16
6 MEMBRANE REGION 151 1134 3.637e-17 3.54e-15
7 SYNAPSE PART 97 610 4.015e-16 3.35e-14
8 EXCITATORY SYNAPSE 48 197 1.402e-15 9.401e-14
9 CELL PROJECTION PART 129 946 1.449e-15 9.401e-14
10 EXTRACELLULAR MATRIX 75 426 4.466e-15 2.608e-13
11 SOMATODENDRITIC COMPARTMENT 98 650 9.325e-15 4.951e-13
12 AXON 73 418 1.607e-14 7.818e-13
13 POSTSYNAPSE 68 378 2.956e-14 1.328e-12
14 PLASMA MEMBRANE REGION 123 929 6.14e-14 2.561e-12
15 PROTEINACEOUS EXTRACELLULAR MATRIX 63 356 5.686e-13 2.214e-11
16 DENDRITE 73 451 8.228e-13 3.003e-11
17 MEMBRANE MICRODOMAIN 54 288 2.535e-12 8.71e-11
18 INTRINSIC COMPONENT OF PLASMA MEMBRANE 180 1649 5.603e-12 1.818e-10
19 CELL LEADING EDGE 57 350 2.137e-10 6.569e-09
20 CELL SURFACE 96 757 4.422e-10 1.291e-08
21 PLASMA MEMBRANE PROTEIN COMPLEX 72 510 7.5e-10 2.086e-08
22 SYNAPTIC MEMBRANE 46 261 8.871e-10 2.355e-08
23 AXON PART 40 219 3.832e-09 9.729e-08
24 CELL BODY 68 494 6.403e-09 1.558e-07
25 CELL CELL JUNCTION 56 383 1.707e-08 3.987e-07
26 EXTRACELLULAR MATRIX COMPONENT 27 125 3.572e-08 8.022e-07
27 SITE OF POLARIZED GROWTH 29 149 1.266e-07 2.739e-06
28 NEURONAL POSTSYNAPTIC DENSITY 16 53 1.726e-07 3.6e-06
29 ACTIN CYTOSKELETON 59 444 2.224e-07 4.478e-06
30 ACTIN BASED CELL PROJECTION 32 181 2.936e-07 5.716e-06
31 INTRACELLULAR VESICLE 128 1259 5.229e-07 9.812e-06
32 SARCOLEMMA 25 125 5.376e-07 9.812e-06
33 POSTSYNAPTIC MEMBRANE 34 205 6.007e-07 1.002e-05
34 ANCHORING JUNCTION 62 489 5.789e-07 1.002e-05
35 PLASMA MEMBRANE RAFT 20 86 5.938e-07 1.002e-05
36 VOLTAGE GATED SODIUM CHANNEL COMPLEX 8 14 7.438e-07 1.207e-05
37 CATION CHANNEL COMPLEX 29 167 1.524e-06 2.405e-05
38 SIDE OF MEMBRANE 55 428 1.644e-06 2.526e-05
39 PRESYNAPSE 41 283 1.75e-06 2.62e-05
40 CELL SUBSTRATE JUNCTION 52 398 1.919e-06 2.801e-05
41 FILOPODIUM 20 94 2.641e-06 3.762e-05
42 LAMELLIPODIUM 29 172 2.818e-06 3.919e-05
43 MAIN AXON 15 58 3.67e-06 4.899e-05
44 RUFFLE 27 156 3.691e-06 4.899e-05
45 T TUBULE 13 45 4.273e-06 5.546e-05
46 SODIUM CHANNEL COMPLEX 8 17 5.032e-06 6.389e-05
47 SECRETORY VESICLE 56 461 7.478e-06 9.292e-05
48 CYTOSKELETON 177 1967 9.67e-06 0.0001152
49 CYTOPLASMIC VESICLE PART 68 601 9.518e-06 0.0001152
50 NEURON SPINE 22 121 1.279e-05 0.0001494
51 GOLGI APPARATUS 135 1445 2.128e-05 0.0002437
52 CONTRACTILE FIBER 31 211 2.336e-05 0.0002623
53 PLATELET ALPHA GRANULE 16 75 2.5e-05 0.0002755
54 CYTOPLASMIC REGION 38 287 3.329e-05 0.00036
55 I BAND 21 121 4.116e-05 0.000437
56 CELL CELL CONTACT ZONE 14 64 5.92e-05 0.0006065
57 TERMINAL BOUTON 14 64 5.92e-05 0.0006065
58 VESICLE MEMBRANE 57 512 7.693e-05 0.0007747
59 TRANSPORTER COMPLEX 40 321 8.291e-05 0.0008207
60 INTERCALATED DISC 12 51 9.344e-05 0.0009095
61 MICROVILLUS 15 75 9.744e-05 0.0009328
62 EXTERNAL SIDE OF PLASMA MEMBRANE 32 238 0.0001007 0.0009488
63 BASEMENT MEMBRANE 17 93 0.0001119 0.001037
64 EXOCYTIC VESICLE 22 142 0.0001573 0.001413
65 FIBRIL 6 14 0.0001554 0.001413
66 MEMBRANE PROTEIN COMPLEX 97 1020 0.0001703 0.001507
67 LEADING EDGE MEMBRANE 21 134 0.0001866 0.001626
68 EXTRINSIC COMPONENT OF CYTOPLASMIC SIDE OF PLASMA MEMBRANE 17 98 0.000217 0.001864
69 PERIKARYON 18 108 0.000241 0.00204
70 SECRETORY GRANULE 41 352 0.000295 0.002461
71 NEURON PROJECTION TERMINUS 20 129 0.0003041 0.002502
72 CYTOPLASMIC SIDE OF MEMBRANE 24 170 0.0003443 0.002793
73 CELL CORTEX 30 238 0.0005023 0.004018
74 SECRETORY GRANULE MEMBRANE 14 78 0.0005329 0.004206
75 ACTOMYOSIN 12 62 0.0006487 0.005051
76 RUFFLE MEMBRANE 14 80 0.000694 0.005307
77 ENDOPLASMIC RETICULUM 140 1631 0.0006998 0.005307
78 FILOPODIUM MEMBRANE 6 18 0.0007639 0.005719
79 PLATELET ALPHA GRANULE LUMEN 11 55 0.0008087 0.005978
80 EXOCYTIC VESICLE MEMBRANE 11 56 0.0009472 0.006915
81 RECEPTOR COMPLEX 37 327 0.0009752 0.007031
82 PLATELET ALPHA GRANULE MEMBRANE 5 13 0.001026 0.007306
83 COSTAMERE 6 19 0.001054 0.00742
84 EXTRINSIC COMPONENT OF MEMBRANE 30 252 0.001279 0.008895
85 EXTRACELLULAR SPACE 119 1376 0.001353 0.009296

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04390_Hippo_signaling_pathway 29 154 2.648e-07 4.766e-05
2 hsa04151_PI3K_AKT_signaling_pathway 48 351 1.299e-06 0.000117
3 hsa04510_Focal_adhesion 32 200 2.834e-06 0.00017
4 hsa04014_Ras_signaling_pathway 35 236 5.785e-06 0.0002603
5 hsa04971_Gastric_acid_secretion 16 74 2.094e-05 0.0007538
6 hsa04514_Cell_adhesion_molecules_.CAMs. 23 136 2.776e-05 0.0008328
7 hsa04020_Calcium_signaling_pathway 27 177 3.944e-05 0.0009158
8 hsa04360_Axon_guidance 22 130 4.07e-05 0.0009158
9 hsa04970_Salivary_secretion 17 89 6.316e-05 0.001232
10 hsa04270_Vascular_smooth_muscle_contraction 20 116 6.846e-05 0.001232
11 hsa04010_MAPK_signaling_pathway 35 268 8.857e-05 0.001449
12 hsa04350_TGF.beta_signaling_pathway 16 85 0.0001232 0.001848
13 hsa04720_Long.term_potentiation 14 70 0.0001649 0.002283
14 hsa04972_Pancreatic_secretion 17 101 0.0003147 0.004047
15 hsa04810_Regulation_of_actin_cytoskeleton 28 214 0.0004175 0.00501
16 hsa04670_Leukocyte_transendothelial_migration 18 117 0.0006551 0.007369
17 hsa04540_Gap_junction 15 90 0.0007723 0.008177
18 hsa04520_Adherens_junction 13 73 0.0008986 0.008337
19 hsa04912_GnRH_signaling_pathway 16 101 0.0009264 0.008337
20 hsa04916_Melanogenesis 16 101 0.0009264 0.008337
21 hsa04914_Progesterone.mediated_oocyte_maturation 14 87 0.001619 0.01387
22 hsa04730_Long.term_depression 12 70 0.001963 0.01606
23 hsa04310_Wnt_signaling_pathway 20 151 0.002265 0.01773
24 hsa04710_Circadian_rhythm_._mammal 6 23 0.003125 0.02344
25 hsa04512_ECM.receptor_interaction 13 85 0.003699 0.02663
26 hsa04722_Neurotrophin_signaling_pathway 17 127 0.004178 0.02892
27 hsa04530_Tight_junction 17 133 0.006666 0.04441
28 hsa04062_Chemokine_signaling_pathway 22 189 0.006908 0.04441
29 hsa04114_Oocyte_meiosis 15 114 0.008039 0.0499
30 hsa04380_Osteoclast_differentiation 16 128 0.01024 0.06144
31 hsa04960_Aldosterone.regulated_sodium_reabsorption 7 42 0.01905 0.1106
32 hsa04150_mTOR_signaling_pathway 8 52 0.01991 0.112
33 hsa04973_Carbohydrate_digestion_and_absorption 7 44 0.02415 0.1317
34 hsa04340_Hedgehog_signaling_pathway 8 56 0.02986 0.1542
35 hsa04640_Hematopoietic_cell_lineage 11 88 0.02999 0.1542
36 hsa04070_Phosphatidylinositol_signaling_system 10 78 0.03216 0.1569
37 hsa04210_Apoptosis 11 89 0.03226 0.1569
38 hsa04920_Adipocytokine_signaling_pathway 9 68 0.0342 0.162
39 hsa04115_p53_signaling_pathway 9 69 0.03712 0.1713
40 hsa04974_Protein_digestion_and_absorption 10 81 0.04028 0.1813
41 hsa04976_Bile_secretion 9 71 0.04345 0.1908
42 hsa04660_T_cell_receptor_signaling_pathway 12 108 0.05277 0.2236
43 hsa00532_Glycosaminoglycan_biosynthesis_._chondroitin_sulfate 4 22 0.05342 0.2236
44 hsa04662_B_cell_receptor_signaling_pathway 9 75 0.0582 0.2381
45 hsa04964_Proximal_tubule_bicarbonate_reclamation 4 23 0.06141 0.2456
46 hsa00230_Purine_metabolism 16 162 0.06973 0.2649
47 hsa00533_Glycosaminoglycan_biosynthesis_._keratan_sulfate 3 15 0.07208 0.2649
48 hsa00604_Glycosphingolipid_biosynthesis_._ganglio_series 3 15 0.07208 0.2649
49 hsa04910_Insulin_signaling_pathway 14 138 0.0721 0.2649
50 hsa04664_Fc_epsilon_RI_signaling_pathway 9 79 0.07583 0.273
51 hsa04144_Endocytosis 19 203 0.07908 0.2791
52 hsa04630_Jak.STAT_signaling_pathway 15 155 0.08828 0.3019
53 hsa00534_Glycosaminoglycan_biosynthesis_._heparan_sulfate 4 26 0.08889 0.3019
54 hsa04666_Fc_gamma_R.mediated_phagocytosis 10 95 0.09631 0.321
55 hsa00531_Glycosaminoglycan_degradation 3 19 0.1266 0.4109
56 hsa04370_VEGF_signaling_pathway 8 76 0.1278 0.4109
57 hsa04260_Cardiac_muscle_contraction 8 77 0.1349 0.426
58 hsa02010_ABC_transporters 5 44 0.1628 0.4966
59 hsa04962_Vasopressin.regulated_water_reabsorption 5 44 0.1628 0.4966
60 hsa00562_Inositol_phosphate_metabolism 6 57 0.1727 0.5181
61 hsa04621_NOD.like_receptor_signaling_pathway 6 59 0.1928 0.569
62 hsa00520_Amino_sugar_and_nucleotide_sugar_metabolism 5 48 0.2088 0.6061
63 hsa04320_Dorso.ventral_axis_formation 3 25 0.2266 0.6474
64 hsa00360_Phenylalanine_metabolism 2 17 0.3108 0.874
65 hsa00512_Mucin_type_O.Glycan_biosynthesis 3 30 0.318 0.8807
66 hsa04012_ErbB_signaling_pathway 7 87 0.3514 0.9442
67 hsa04672_Intestinal_immune_network_for_IgA_production 4 49 0.4074 1
68 hsa04742_Taste_transduction 4 52 0.4525 1
69 hsa00910_Nitrogen_metabolism 2 23 0.4545 1
70 hsa04145_Phagosome 11 156 0.4563 1
71 hsa04622_RIG.I.like_receptor_signaling_pathway 5 71 0.508 1
72 hsa00350_Tyrosine_metabolism 3 41 0.5144 1
73 hsa04620_Toll.like_receptor_signaling_pathway 7 102 0.5146 1
74 hsa00601_Glycosphingolipid_biosynthesis_._lacto_and_neolacto_series 2 26 0.5198 1
75 hsa04966_Collecting_duct_acid_secretion 2 27 0.5404 1
76 hsa00590_Arachidonic_acid_metabolism 4 59 0.5526 1
77 hsa00310_Lysine_degradation 3 44 0.5629 1
78 hsa03015_mRNA_surveillance_pathway 5 83 0.6481 1
79 hsa04140_Regulation_of_autophagy 2 34 0.6668 1
80 hsa04610_Complement_and_coagulation_cascades 4 69 0.6766 1
81 hsa04650_Natural_killer_cell_mediated_cytotoxicity 8 136 0.6829 1
82 hsa03022_Basal_transcription_factors 2 37 0.7117 1
83 hsa04110_Cell_cycle 7 128 0.7488 1
84 hsa00600_Sphingolipid_metabolism 2 40 0.7514 1
85 hsa00380_Tryptophan_metabolism 2 42 0.7752 1
86 hsa00514_Other_types_of_O.glycan_biosynthesis 2 46 0.8168 1
87 hsa04975_Fat_digestion_and_absorption 2 46 0.8168 1
88 hsa04330_Notch_signaling_pathway 2 47 0.8261 1
89 hsa00510_N.Glycan_biosynthesis 2 49 0.8434 1
90 hsa03320_PPAR_signaling_pathway 3 70 0.8496 1
91 hsa04141_Protein_processing_in_endoplasmic_reticulum 8 168 0.8726 1
92 hsa04623_Cytosolic_DNA.sensing_pathway 2 56 0.8923 1
93 hsa00140_Steroid_hormone_biosynthesis 2 57 0.898 1
94 hsa00240_Pyrimidine_metabolism 4 99 0.8994 1
95 hsa00564_Glycerophospholipid_metabolism 3 80 0.9055 1
96 hsa04142_Lysosome 5 121 0.9083 1
97 hsa00980_Metabolism_of_xenobiotics_by_cytochrome_P450 2 71 0.9532 1
98 hsa03018_RNA_degradation 2 71 0.9532 1
99 hsa00982_Drug_metabolism_._cytochrome_P450 2 73 0.9582 1
100 hsa04612_Antigen_processing_and_presentation 2 78 0.9687 1
101 hsa04120_Ubiquitin_mediated_proteolysis 4 139 0.9842 1
102 hsa03013_RNA_transport 2 152 0.9996 1
103 hsa04740_Olfactory_transduction 5 388 1 1

Quest ID: 74b256607a26ab1e52b4cb11dba0c788