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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-429 ABCA1 4.49 0 -0.71 0.00276 miRNATAP -0.11 0 NA
2 hsa-miR-429 ABCA9 4.49 0 -3.14 0 miRanda -0.11 0.03127 NA
3 hsa-miR-429 ABCB1 4.49 0 -2.33 0 miRanda -0.11 0.00034 NA
4 hsa-miR-429 ABCB4 4.49 0 -1.92 0 miRanda -0.25 0 NA
5 hsa-miR-429 ABCC9 4.49 0 -2.76 0 miRanda; miRNATAP -0.39 0 NA
6 hsa-miR-429 ABCD2 4.49 0 -3.08 0 miRanda -0.46 0 NA
7 hsa-miR-429 ABL2 4.49 0 -0.32 0.04554 MirTarget -0.13 0 NA
8 hsa-miR-429 ACAT1 4.49 0 -1.05 0 miRanda -0.19 0 NA
9 hsa-miR-429 ACE 4.49 0 -0.35 0.17613 miRanda -0.13 0 NA
10 hsa-miR-429 ACO1 4.49 0 -0.65 0.00055 miRanda -0.12 0 NA
11 hsa-miR-429 ACOX2 4.49 0 -3.75 0 miRanda; miRNATAP -0.47 0 NA
12 hsa-miR-429 ACTC1 4.49 0 -7.19 0 MirTarget; miRanda; miRNATAP -0.99 0 NA
13 hsa-miR-429 ACTN1 4.49 0 -1.05 0.00011 miRanda -0.32 0 NA
14 hsa-miR-429 ACTN2 4.49 0 -3.37 0 miRanda -0.51 0 NA
15 hsa-miR-429 ACVR1 4.49 0 -0.44 0.01143 miRNATAP -0.13 0 NA
16 hsa-miR-429 ACVRL1 4.49 0 -1.25 0 miRNATAP -0.2 0 NA
17 hsa-miR-429 ADAM12 4.49 0 0.88 0.05623 miRanda; miRNATAP -0.3 0 NA
18 hsa-miR-429 ADAM19 4.49 0 -1.06 0.01895 miRanda; miRNATAP -0.44 0 NA
19 hsa-miR-429 ADAM23 4.49 0 -1.05 0.04992 miRanda -0.23 0 NA
20 hsa-miR-429 ADAMDEC1 4.49 0 0.24 0.71291 miRanda -0.36 0 NA
21 hsa-miR-429 ADAMTS1 4.49 0 -3.81 0 miRanda -0.24 0 NA
22 hsa-miR-429 ADAMTS10 4.49 0 -1.26 0.00027 miRNATAP -0.26 0 NA
23 hsa-miR-429 ADAMTS16 4.49 0 -1.54 0.01905 miRanda; miRNATAP -0.51 0 NA
24 hsa-miR-429 ADAMTS18 4.49 0 -0.74 0.14599 miRanda; miRNATAP -0.19 1.0E-5 NA
25 hsa-miR-429 ADAMTS2 4.49 0 -0.77 0.15763 miRNATAP -0.44 0 NA
26 hsa-miR-429 ADAMTS3 4.49 0 -1.18 0.00448 PITA; miRanda; miRNATAP -0.34 0 NA
27 hsa-miR-429 ADAMTS4 4.49 0 -2.17 0 miRanda -0.36 0 NA
28 hsa-miR-429 ADAMTS6 4.49 0 -0.88 0.01914 miRNATAP -0.34 0 NA
29 hsa-miR-429 ADAMTS9 4.49 0 -1.79 0 PITA; miRanda -0.21 0 NA
30 hsa-miR-429 ADAP2 4.49 0 0.02 0.93649 miRanda -0.23 0 NA
31 hsa-miR-429 ADCY2 4.49 0 -3.87 0 MirTarget; PITA; miRanda; miRNATAP -0.25 0 NA
32 hsa-miR-429 ADCY5 4.49 0 -5.17 0 miRNATAP -0.38 0 NA
33 hsa-miR-429 ADCY7 4.49 0 0.3 0.34571 miRanda -0.24 0 NA
34 hsa-miR-429 ADCY9 4.49 0 -1.5 0 miRanda; miRNATAP -0.24 0 NA
35 hsa-miR-429 ADCYAP1 4.49 0 -3.51 0 miRanda -0.35 0 NA
36 hsa-miR-429 ADH1B 4.49 0 -7.89 0 miRanda -0.43 0 NA
37 hsa-miR-429 ADIPOQ 4.49 0 -5.02 0 miRanda -0.66 0 NA
38 hsa-miR-429 ADORA3 4.49 0 -0.39 0.2849 miRNATAP -0.31 0 NA
39 hsa-miR-429 ADRA2A 4.49 0 -2.58 0 miRNATAP -0.2 0 NA
40 hsa-miR-429 AFF2 4.49 0 -1.73 0.00201 miRNATAP -0.19 8.0E-5 NA
41 hsa-miR-429 AFF3 4.49 0 -5 0 MirTarget; PITA; miRanda; miRNATAP -0.43 0 NA
42 hsa-miR-429 AGFG1 4.49 0 -0.17 0.30925 MirTarget; miRanda; miRNATAP -0.1 0 NA
43 hsa-miR-429 AGPAT4 4.49 0 -0.79 0.01174 miRNATAP -0.21 0 NA
44 hsa-miR-429 AHNAK 4.49 0 -1.66 0 PITA; miRanda; miRNATAP -0.19 0 NA
45 hsa-miR-429 AKAP13 4.49 0 -1.15 0 miRNATAP -0.13 0 NA
46 hsa-miR-429 AKAP2 4.49 0 -2.51 8.0E-5 PITA; miRanda; miRNATAP -0.51 0 NA
47 hsa-miR-429 AKAP5 4.49 0 0.05 0.84509 miRanda -0.13 0 NA
48 hsa-miR-429 AKAP6 4.49 0 -3.34 0 miRanda -0.39 0 NA
49 hsa-miR-429 ALDH1A1 4.49 0 -2.52 2.0E-5 miRanda -0.3 0 NA
50 hsa-miR-429 ALDH1L2 4.49 0 -1.12 0.02448 miRanda -0.49 0 NA
51 hsa-miR-429 ALDH7A1 4.49 0 -1.69 0.00179 miRanda -0.19 6.0E-5 NA
52 hsa-miR-429 ALX1 4.49 0 -0.87 0.17254 miRanda -0.23 5.0E-5 NA
53 hsa-miR-429 AMOTL2 4.49 0 -1.01 0.00015 MirTarget; PITA; miRanda; miRNATAP -0.23 0 NA
54 hsa-miR-429 ANGPT1 4.49 0 -2 1.0E-5 miRanda -0.32 0 NA
55 hsa-miR-429 ANK2 4.49 0 -4.32 0 miRanda; miRNATAP -0.54 0 NA
56 hsa-miR-429 ANKH 4.49 0 -0.38 0.21654 PITA; miRanda; miRNATAP -0.26 0 NA
57 hsa-miR-429 ANKS1B 4.49 0 -3.65 0 miRanda -0.39 0 NA
58 hsa-miR-429 ANO5 4.49 0 -3.19 0 miRanda -0.17 0.00049 NA
59 hsa-miR-429 ANTXR2 4.49 0 -2.31 0 miRNATAP -0.31 0 NA
60 hsa-miR-429 AP1S2 4.49 0 -1.31 0 MirTarget; PITA; miRanda; miRNATAP -0.29 0 NA
61 hsa-miR-429 AP4S1 4.49 0 -0.6 0.00055 miRanda; miRNATAP -0.11 0 NA
62 hsa-miR-429 APBB1 4.49 0 -2.48 0 miRNATAP -0.33 0 NA
63 hsa-miR-429 APCDD1L 4.49 0 -2.55 0.0003 miRNATAP -0.73 0 NA
64 hsa-miR-429 APLN 4.49 0 1.77 1.0E-5 miRNATAP -0.13 0.0002 NA
65 hsa-miR-429 APP 4.49 0 -0.4 0.04288 miRanda -0.12 0 NA
66 hsa-miR-429 AREG 4.49 0 -1.82 0.00455 miRanda -0.19 0.00063 NA
67 hsa-miR-429 ARHGAP1 4.49 0 -0.88 0 miRNATAP -0.12 0 NA
68 hsa-miR-429 ARHGAP15 4.49 0 -1.33 0.00101 miRanda -0.28 0 NA
69 hsa-miR-429 ARHGAP20 4.49 0 -3.52 0 MirTarget; miRanda; miRNATAP -0.4 0 NA
70 hsa-miR-429 ARHGAP24 4.49 0 -2.02 0 miRanda; miRNATAP -0.33 0 NA
71 hsa-miR-429 ARHGAP25 4.49 0 -0.72 0.00654 miRNATAP -0.21 0 NA
72 hsa-miR-429 ARHGAP28 4.49 0 -1.54 0.00053 MirTarget -0.11 0.00664 NA
73 hsa-miR-429 ARHGAP29 4.49 0 -0.34 0.31665 miRanda -0.15 0 NA
74 hsa-miR-429 ARHGEF10 4.49 0 -1.15 1.0E-5 miRanda -0.2 0 NA
75 hsa-miR-429 ARHGEF17 4.49 0 -1.19 0 PITA; miRanda; miRNATAP -0.18 0 NA
76 hsa-miR-429 ARHGEF3 4.49 0 -0.76 0 MirTarget; PITA; miRanda; miRNATAP -0.11 0 NA
77 hsa-miR-429 ARHGEF4 4.49 0 -1.44 0.0131 miRNATAP -0.27 0 NA
78 hsa-miR-429 ARHGEF6 4.49 0 -1.32 0 miRanda; mirMAP -0.13 0 NA
79 hsa-miR-429 ARID5B 4.49 0 -1.57 0 miRanda; miRNATAP -0.13 0 NA
80 hsa-miR-429 ARL10 4.49 0 -1.12 0.00198 mirMAP -0.18 0 NA
81 hsa-miR-429 ARL4A 4.49 0 -0.62 0.01525 miRanda; miRNATAP -0.11 0 NA
82 hsa-miR-429 ARL4C 4.49 0 -0.28 0.33535 miRNATAP -0.19 0 NA
83 hsa-miR-429 ARMC9 4.49 0 -0.17 0.43502 miRanda -0.15 0 NA
84 hsa-miR-429 ARMCX1 4.49 0 -2.16 0 miRanda -0.25 0 NA
85 hsa-miR-429 ARNTL 4.49 0 -0.36 0.08956 miRNATAP -0.15 0 NA
86 hsa-miR-429 ARSB 4.49 0 -0.58 0.00052 miRanda -0.17 0 NA
87 hsa-miR-429 ARSJ 4.49 0 -1.58 0.00066 miRanda -0.41 0 NA
88 hsa-miR-429 ASAP1 4.49 0 0.06 0.77944 MirTarget; miRanda; miRNATAP -0.13 0 NA
89 hsa-miR-429 ASB5 4.49 0 -6.18 0 miRanda; miRNATAP -0.76 0 NA
90 hsa-miR-429 ASPN 4.49 0 0.18 0.73898 miRanda -0.32 0 NA
91 hsa-miR-429 ASXL3 4.49 0 -3.34 0 miRanda -0.17 0.00038 NA
92 hsa-miR-429 ATF3 4.49 0 -3.23 0 miRanda -0.16 3.0E-5 NA
93 hsa-miR-429 ATP1A2 4.49 0 -6.96 0 miRNATAP -0.56 0 NA
94 hsa-miR-429 ATP1B2 4.49 0 -3.02 0 miRNATAP -0.11 0.00051 NA
95 hsa-miR-429 ATP6V0D2 4.49 0 2.26 0 miRanda -0.16 0.00021 NA
96 hsa-miR-429 ATP6V1B2 4.49 0 -0.17 0.24474 miRNATAP -0.11 0 NA
97 hsa-miR-429 ATP8A1 4.49 0 -1.48 8.0E-5 miRanda; miRNATAP -0.13 7.0E-5 NA
98 hsa-miR-429 ATXN1 4.49 0 -1.51 0 MirTarget; PITA; miRNATAP -0.23 0 NA
99 hsa-miR-429 AXIN2 4.49 0 -1.7 6.0E-5 miRanda -0.11 0.00355 NA
100 hsa-miR-429 B3GALT2 4.49 0 -3.85 0 miRNATAP -0.21 0 NA
101 hsa-miR-429 B4GALNT1 4.49 0 -0.59 0.29462 miRNATAP -0.38 0 NA
102 hsa-miR-429 BACE1 4.49 0 -0.72 0.00096 miRNATAP -0.18 0 NA
103 hsa-miR-429 BACH2 4.49 0 -1.52 0.00134 PITA; mirMAP; miRNATAP -0.44 0 NA
104 hsa-miR-429 BASP1 4.49 0 -0.12 0.79725 PITA; miRanda; miRNATAP -0.14 0.00024 NA
105 hsa-miR-429 BCHE 4.49 0 -4.37 0 miRanda -0.52 0 NA
106 hsa-miR-429 BCL2 4.49 0 -2.02 0 miRNAWalker2 validate; miRTarBase; PITA; mirMAP -0.15 0 23999873; 26513239; 26511969 MiR 429 up regulation induces apoptosis and suppresses invasion by targeting Bcl 2 and SP 1 in esophageal carcinoma; Subsequent Western blotting and luciferase reporter assays showed that miR-429 can bind to putative binding sites within the Bcl-2 and SP1 mRNA 3' untranslated regions UTRs to reduce their expression; Up-regulation of miR-429 inhibits invasion and promotes apoptosis in EC cells by targeting Bcl-2 and SP1; Our findings suggest that Bcl-2 and SP1 may serve as major targets of miR-429;MiR 429 Induces Gastric Carcinoma Cell Apoptosis Through Bcl 2; Here we studied the levels of miR-429 and anti-apoptotic protein Bcl-2 in GC specimens; We performed bioinformatics analyses and used luciferase-reporter assay to analyze the relationship between miR-429 and Bcl-2 in GC cells; MiR-429 levels were significantly decreased and Bcl-2 levels were significantly increased in GC specimens compared to the paired adjacent non-tumor gastric tissue; Moreover the levels of miR-429 and Bcl-2 inversely correlated in GC specimens; Bioinformatics analyses showed that miR-429 targeted the 3'-UTR of Bcl-2 mRNA to inhibit its translation which was confirmed by luciferase-reporter assay;MiR 429 induces apoptosis of glioblastoma cell through Bcl 2; Here we analyzed the levels of miR-429 and anti-apoptotic protein Bcl-2 in GBM specimens; We combined bioinformatics analyses and luciferase reporter assay to determine the relationship between miR-429 and Bcl-2 in GBM cells; We found that miR-429 levels were significantly decreased and Bcl-2 levels were significantly increased in GBM specimens compared to the paired adjacent non-tumor brain tissue; Moreover the levels of miR-429 and Bcl-2 inversely correlated; MiR-429 targeted the 3'-UTR of Bcl-2 mRNA to inhibit its translation
107 hsa-miR-429 BCL2L2 4.49 0 -1.27 0 miRNATAP -0.11 0 NA
108 hsa-miR-429 BCO2 4.49 0 -2.28 0 miRanda -0.11 0.00099 NA
109 hsa-miR-429 BEND4 4.49 0 -1.97 7.0E-5 mirMAP; miRNATAP -0.24 0 NA
110 hsa-miR-429 BHLHE22 4.49 0 -1.78 1.0E-5 miRanda -0.13 0.00017 NA
111 hsa-miR-429 BHLHE40 4.49 0 -0.75 0.00869 miRNATAP -0.11 1.0E-5 NA
112 hsa-miR-429 BMP1 4.49 0 0.19 0.45337 miRNATAP -0.19 0 NA
113 hsa-miR-429 BMPER 4.49 0 -2.38 0 PITA; miRanda -0.3 0 NA
114 hsa-miR-429 BMPR1B 4.49 0 0.07 0.91404 miRNATAP -0.33 0 NA
115 hsa-miR-429 BNC2 4.49 0 -2.95 0 MirTarget; PITA; miRNATAP -0.53 0 NA
116 hsa-miR-429 BRMS1L 4.49 0 -0.51 0.00391 PITA; miRanda; miRNATAP -0.1 0 NA
117 hsa-miR-429 BTLA 4.49 0 -1.31 0.00559 miRNATAP -0.32 0 NA
118 hsa-miR-429 C11orf87 4.49 0 -1.55 0.01186 miRNATAP -0.24 1.0E-5 NA
119 hsa-miR-429 C11orf95 4.49 0 -0.85 0 miRNATAP -0.12 0 NA
120 hsa-miR-429 C17orf51 4.49 0 -0.68 0.02254 mirMAP -0.19 0 NA
121 hsa-miR-429 C3orf18 4.49 0 -1.41 0 miRNATAP -0.13 0 NA
122 hsa-miR-429 C5 4.49 0 -0.99 0.00071 miRanda -0.16 0 NA
123 hsa-miR-429 C8orf46 4.49 0 -1.63 0.00027 miRNATAP -0.16 3.0E-5 NA
124 hsa-miR-429 CA3 4.49 0 -2.42 0 miRanda -0.23 0 NA
125 hsa-miR-429 CACHD1 4.49 0 -1.73 0 miRanda; miRNATAP -0.17 0 NA
126 hsa-miR-429 CACNA1C 4.49 0 -2.53 0 MirTarget; PITA; miRanda; miRNATAP -0.29 0 NA
127 hsa-miR-429 CACNA2D3 4.49 0 -1.05 0.019 miRanda -0.13 0.00127 NA
128 hsa-miR-429 CACNA2D4 4.49 0 -0.11 0.70014 miRanda -0.21 0 NA
129 hsa-miR-429 CACNB2 4.49 0 -2.97 0 PITA; miRanda; miRNATAP -0.17 0 NA
130 hsa-miR-429 CACNB4 4.49 0 -2.87 0 PITA; miRanda; miRNATAP -0.18 1.0E-5 NA
131 hsa-miR-429 CADM2 4.49 0 -3.84 0 miRanda; miRNATAP -0.17 0.00086 NA
132 hsa-miR-429 CALD1 4.49 0 -2.47 0 miRanda -0.43 0 NA
133 hsa-miR-429 CALU 4.49 0 -0.15 0.46318 MirTarget; PITA; miRanda -0.18 0 NA
134 hsa-miR-429 CAMK2A 4.49 0 -4.14 0 miRNATAP -0.62 0 NA
135 hsa-miR-429 CAND2 4.49 0 -1.77 1.0E-5 miRanda -0.22 0 NA
136 hsa-miR-429 CAP2 4.49 0 -2.19 0 miRanda -0.32 0 NA
137 hsa-miR-429 CAPN6 4.49 0 -3.48 0 miRanda -0.32 0 NA
138 hsa-miR-429 CAPZA2 4.49 0 -0.83 0 miRanda -0.11 0 NA
139 hsa-miR-429 CASP1 4.49 0 -0.39 0.33513 miRanda -0.24 0 NA
140 hsa-miR-429 CASQ2 4.49 0 -6.22 0 miRanda; miRNATAP -0.72 0 NA
141 hsa-miR-429 CAV2 4.49 0 -0.86 0.01061 miRNATAP -0.26 0 NA
142 hsa-miR-429 CCDC102B 4.49 0 -0.84 0.00179 miRanda -0.16 0 NA
143 hsa-miR-429 CCDC3 4.49 0 -1.68 0 miRanda -0.17 0 NA
144 hsa-miR-429 CCDC69 4.49 0 -2.71 0 miRNATAP -0.21 0 NA
145 hsa-miR-429 CCDC85A 4.49 0 -1.95 0 miRanda; miRNATAP -0.1 0.0038 NA
146 hsa-miR-429 CCDC88A 4.49 0 -0.76 0.01199 miRNATAP -0.27 0 NA
147 hsa-miR-429 CCL11 4.49 0 -1 0.13155 miRanda -0.31 0 NA
148 hsa-miR-429 CCL8 4.49 0 -1.17 0.03345 miRanda -0.48 0 NA
149 hsa-miR-429 CCND2 4.49 0 -2.43 0 miRNATAP -0.32 0 NA
150 hsa-miR-429 CCR1 4.49 0 -0.05 0.89095 miRanda; miRNATAP -0.32 0 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 254 1672 5.138e-42 2.391e-38
2 BIOLOGICAL ADHESION 182 1032 2.955e-38 6.876e-35
3 REGULATION OF CELLULAR COMPONENT MOVEMENT 146 771 4.26e-34 6.607e-31
4 REGULATION OF CELL DIFFERENTIATION 218 1492 3.841e-33 4.468e-30
5 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 203 1395 1.605e-30 1.244e-27
6 CELL DEVELOPMENT 206 1426 1.514e-30 1.244e-27
7 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 164 1021 1.899e-29 1.263e-26
8 NEUROGENESIS 201 1402 2.486e-29 1.446e-26
9 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 175 1142 6.564e-29 3.393e-26
10 REGULATION OF CELL PROLIFERATION 206 1496 1.059e-27 4.928e-25
11 CARDIOVASCULAR SYSTEM DEVELOPMENT 136 788 1.554e-27 6.027e-25
12 CIRCULATORY SYSTEM DEVELOPMENT 136 788 1.554e-27 6.027e-25
13 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 184 1275 3.888e-27 1.392e-24
14 VASCULATURE DEVELOPMENT 99 469 4.771e-27 1.586e-24
15 LOCOMOTION 168 1114 6.309e-27 1.957e-24
16 TISSUE DEVELOPMENT 206 1518 7.408e-27 2.154e-24
17 POSITIVE REGULATION OF RESPONSE TO STIMULUS 242 1929 1.292e-26 3.537e-24
18 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 233 1848 7.089e-26 1.832e-23
19 REGULATION OF CELL DEVELOPMENT 137 836 1.836e-25 4.496e-23
20 BLOOD VESSEL MORPHOGENESIS 83 364 3.482e-25 8.101e-23
21 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 212 1656 2.68e-24 5.938e-22
22 CELL CELL ADHESION 108 608 5.431e-23 1.149e-20
23 POSITIVE REGULATION OF CELL DIFFERENTIATION 130 823 1.073e-22 2.17e-20
24 REGULATION OF NEURON DIFFERENTIATION 101 554 2.007e-22 3.891e-20
25 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 145 983 2.702e-22 5.028e-20
26 EXTRACELLULAR STRUCTURE ORGANIZATION 70 304 1.142e-21 2.044e-19
27 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 95 513 1.212e-21 2.089e-19
28 POSITIVE REGULATION OF CELL COMMUNICATION 193 1532 2.969e-21 4.934e-19
29 RESPONSE TO ENDOGENOUS STIMULUS 184 1450 1.342e-20 2.153e-18
30 NEURON DIFFERENTIATION 130 874 2.373e-20 3.68e-18
31 POSITIVE REGULATION OF CELL PROLIFERATION 124 814 2.579e-20 3.871e-18
32 REGULATION OF CELL ADHESION 105 629 2.863e-20 4.163e-18
33 RESPONSE TO EXTERNAL STIMULUS 215 1821 3.3e-20 4.653e-18
34 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 121 799 1.256e-19 1.669e-17
35 REGULATION OF PHOSPHORUS METABOLIC PROCESS 196 1618 1.246e-19 1.669e-17
36 ANGIOGENESIS 65 293 2.648e-19 3.422e-17
37 RESPONSE TO WOUNDING 96 563 2.935e-19 3.69e-17
38 RESPONSE TO OXYGEN CONTAINING COMPOUND 174 1381 3.72e-19 4.556e-17
39 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 115 750 4.074e-19 4.861e-17
40 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 142 1036 7.056e-19 8.008e-17
41 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 142 1036 7.056e-19 8.008e-17
42 NEGATIVE REGULATION OF CELL PROLIFERATION 103 643 1.416e-18 1.569e-16
43 CELL MOTILITY 122 835 1.668e-18 1.764e-16
44 LOCALIZATION OF CELL 122 835 1.668e-18 1.764e-16
45 MUSCLE STRUCTURE DEVELOPMENT 80 432 2.174e-18 2.199e-16
46 CELLULAR COMPONENT MORPHOGENESIS 128 900 2.151e-18 2.199e-16
47 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 170 1360 2.262e-18 2.239e-16
48 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 138 1008 2.573e-18 2.494e-16
49 ORGAN MORPHOGENESIS 122 841 2.977e-18 2.827e-16
50 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 125 876 4.27e-18 3.974e-16
51 NEGATIVE REGULATION OF CELL COMMUNICATION 154 1192 5.501e-18 5.019e-16
52 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 132 957 8.111e-18 7.258e-16
53 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 117 801 9.098e-18 7.987e-16
54 TAXIS 82 464 1.497e-17 1.29e-15
55 REGULATION OF NEURON PROJECTION DEVELOPMENT 75 408 3.979e-17 3.366e-15
56 POSITIVE REGULATION OF CELL DEVELOPMENT 82 472 4.269e-17 3.547e-15
57 REGULATION OF CELL PROJECTION ORGANIZATION 91 558 4.971e-17 4.058e-15
58 CELL ACTIVATION 92 568 5.194e-17 4.167e-15
59 POSITIVE REGULATION OF LOCOMOTION 75 420 2.086e-16 1.645e-14
60 NEURON PROJECTION DEVELOPMENT 88 545 3.113e-16 2.414e-14
61 SINGLE ORGANISM CELL ADHESION 78 459 9.122e-16 6.958e-14
62 NEURON DEVELOPMENT 101 687 1.192e-15 8.944e-14
63 REGULATION OF PROTEIN MODIFICATION PROCESS 191 1710 1.993e-15 1.472e-13
64 HEART DEVELOPMENT 78 466 2.157e-15 1.548e-13
65 CENTRAL NERVOUS SYSTEM DEVELOPMENT 118 872 2.162e-15 1.548e-13
66 NEURON PROJECTION MORPHOGENESIS 71 402 2.428e-15 1.712e-13
67 POSITIVE REGULATION OF NEURON DIFFERENTIATION 60 306 2.881e-15 2.001e-13
68 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 172 1492 3.583e-15 2.452e-13
69 WOUND HEALING 77 470 1.078e-14 7.269e-13
70 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 66 368 1.112e-14 7.393e-13
71 INTRACELLULAR SIGNAL TRANSDUCTION 177 1572 1.228e-14 8.048e-13
72 SKELETAL SYSTEM DEVELOPMENT 75 455 1.738e-14 1.123e-12
73 IMMUNE SYSTEM PROCESS 210 1984 1.84e-14 1.173e-12
74 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 73 437 1.946e-14 1.223e-12
75 POSITIVE REGULATION OF MOLECULAR FUNCTION 193 1791 4.788e-14 2.942e-12
76 REGULATION OF CELL MORPHOGENESIS 84 552 4.806e-14 2.942e-12
77 MUSCLE SYSTEM PROCESS 55 282 5.287e-14 3.195e-12
78 CELL PROJECTION ORGANIZATION 117 902 5.93e-14 3.537e-12
79 CONNECTIVE TISSUE DEVELOPMENT 44 194 7.416e-14 4.368e-12
80 REGULATION OF CELL DEATH 166 1472 8.193e-14 4.765e-12
81 REGULATION OF MAPK CASCADE 94 660 8.655e-14 4.972e-12
82 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 137 1135 1.042e-13 5.912e-12
83 REGULATION OF TRANSPORT 192 1804 1.846e-13 1.035e-11
84 RESPONSE TO ORGANIC CYCLIC COMPOUND 117 917 1.869e-13 1.035e-11
85 BEHAVIOR 79 516 2.021e-13 1.106e-11
86 NEGATIVE REGULATION OF CELL DIFFERENTIATION 88 609 2.434e-13 1.317e-11
87 CIRCULATORY SYSTEM PROCESS 63 366 3.12e-13 1.669e-11
88 NEGATIVE REGULATION OF LOCOMOTION 51 263 5.554e-13 2.937e-11
89 REGULATION OF HOMEOSTATIC PROCESS 71 447 5.708e-13 2.984e-11
90 POSITIVE REGULATION OF CELL ADHESION 63 376 1.079e-12 5.578e-11
91 POSITIVE REGULATION OF CATALYTIC ACTIVITY 166 1518 1.137e-12 5.814e-11
92 RESPONSE TO LIPID 112 888 1.362e-12 6.89e-11
93 POSITIVE REGULATION OF GENE EXPRESSION 183 1733 1.533e-12 7.587e-11
94 RESPONSE TO CYTOKINE 96 714 1.527e-12 7.587e-11
95 TISSUE MORPHOGENESIS 78 533 3.058e-12 1.498e-10
96 REGULATION OF VASCULATURE DEVELOPMENT 46 233 3.969e-12 1.924e-10
97 RESPONSE TO HORMONE 111 893 4.409e-12 2.115e-10
98 POSITIVE REGULATION OF HYDROLASE ACTIVITY 112 905 4.642e-12 2.204e-10
99 GROWTH 65 410 6.048e-12 2.814e-10
100 REGULATION OF ION TRANSPORT 83 592 6.018e-12 2.814e-10
101 REGULATION OF IMMUNE SYSTEM PROCESS 154 1403 6.288e-12 2.897e-10
102 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 33 133 7.186e-12 3.278e-10
103 CELL CELL SIGNALING 99 767 7.74e-12 3.496e-10
104 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 57 337 8.842e-12 3.956e-10
105 LEUKOCYTE ACTIVATION 65 414 9.379e-12 4.156e-10
106 NEURON PROJECTION GUIDANCE 42 205 9.727e-12 4.27e-10
107 MESENCHYME DEVELOPMENT 40 190 1.239e-11 5.389e-10
108 REGULATION OF SYSTEM PROCESS 74 507 1.274e-11 5.458e-10
109 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 45 232 1.279e-11 5.458e-10
110 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 185 1805 1.557e-11 6.585e-10
111 REGULATION OF METAL ION TRANSPORT 55 325 2.011e-11 8.43e-10
112 MUSCLE CELL DIFFERENTIATION 45 237 2.717e-11 1.129e-09
113 CELLULAR RESPONSE TO NITROGEN COMPOUND 73 505 2.788e-11 1.148e-09
114 RESPONSE TO GROWTH FACTOR 70 475 2.962e-11 1.209e-09
115 EPITHELIUM DEVELOPMENT 113 945 3.275e-11 1.321e-09
116 LEUKOCYTE DIFFERENTIATION 51 292 3.321e-11 1.321e-09
117 HEAD DEVELOPMENT 92 709 3.306e-11 1.321e-09
118 IMMUNE SYSTEM DEVELOPMENT 80 582 3.992e-11 1.574e-09
119 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 52 303 4.181e-11 1.635e-09
120 REGULATION OF EPITHELIAL CELL PROLIFERATION 50 285 4.386e-11 1.701e-09
121 DEVELOPMENTAL GROWTH 55 333 5.286e-11 2.033e-09
122 MORPHOGENESIS OF A BRANCHING STRUCTURE 36 167 6.443e-11 2.457e-09
123 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 117 1004 7.368e-11 2.787e-09
124 NEPHRON DEVELOPMENT 29 115 8.743e-11 3.281e-09
125 HOMOPHILIC CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 34 153 9.11e-11 3.391e-09
126 RESPONSE TO NITROGEN COMPOUND 104 859 1.027e-10 3.793e-09
127 MUSCLE TISSUE DEVELOPMENT 48 275 1.288e-10 4.717e-09
128 POSITIVE REGULATION OF MAPK CASCADE 68 470 1.298e-10 4.719e-09
129 REGULATION OF CELL CELL ADHESION 59 380 1.357e-10 4.894e-09
130 LYMPHOCYTE ACTIVATION 55 342 1.498e-10 5.363e-09
131 MUSCLE ORGAN DEVELOPMENT 48 277 1.666e-10 5.917e-09
132 SINGLE ORGANISM BEHAVIOR 59 384 2.071e-10 7.3e-09
133 REGULATION OF DEVELOPMENTAL GROWTH 49 289 2.354e-10 8.236e-09
134 CELLULAR RESPONSE TO LIPID 66 457 2.635e-10 9.15e-09
135 POSITIVE REGULATION OF CELL DEATH 80 605 2.692e-10 9.278e-09
136 CHEMICAL HOMEOSTASIS 104 874 2.777e-10 9.431e-09
137 REGULATION OF HYDROLASE ACTIVITY 142 1327 2.771e-10 9.431e-09
138 REGULATION OF GTPASE ACTIVITY 86 673 3.243e-10 1.094e-08
139 LEUKOCYTE CELL CELL ADHESION 45 255 3.368e-10 1.127e-08
140 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 178 1784 3.561e-10 1.184e-08
141 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 42 229 3.828e-10 1.263e-08
142 REGULATION OF ACTIN FILAMENT BASED PROCESS 51 312 3.878e-10 1.271e-08
143 HEART MORPHOGENESIS 40 212 4.167e-10 1.356e-08
144 CELL PART MORPHOGENESIS 82 633 4.388e-10 1.418e-08
145 CELL CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 39 204 4.61e-10 1.479e-08
146 REGULATION OF CELL ACTIVATION 68 484 4.696e-10 1.497e-08
147 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 47 278 6.039e-10 1.911e-08
148 REGULATION OF HOMOTYPIC CELL CELL ADHESION 50 307 6.559e-10 2.062e-08
149 STEM CELL DIFFERENTIATION 37 190 7.488e-10 2.338e-08
150 FOREBRAIN DEVELOPMENT 55 357 7.703e-10 2.389e-08
151 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 102 867 7.826e-10 2.397e-08
152 UROGENITAL SYSTEM DEVELOPMENT 49 299 7.829e-10 2.397e-08
153 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 126 1152 8.037e-10 2.444e-08
154 REGULATION OF CARTILAGE DEVELOPMENT 20 63 9.034e-10 2.729e-08
155 ACTIN FILAMENT BASED PROCESS 64 450 9.309e-10 2.795e-08
156 LYMPHOCYTE DIFFERENTIATION 39 209 9.614e-10 2.867e-08
157 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 86 689 1.047e-09 3.102e-08
158 RESPONSE TO MECHANICAL STIMULUS 39 210 1.11e-09 3.269e-08
159 REGULATION OF MEMBRANE POTENTIAL 53 343 1.408e-09 4.119e-08
160 REGULATION OF BLOOD CIRCULATION 48 295 1.487e-09 4.325e-08
161 CELLULAR RESPONSE TO CYTOKINE STIMULUS 78 606 1.592e-09 4.579e-08
162 REGULATION OF MUSCLE SYSTEM PROCESS 37 195 1.594e-09 4.579e-08
163 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 72 541 1.624e-09 4.608e-08
164 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 72 541 1.624e-09 4.608e-08
165 TUBE DEVELOPMENT 73 552 1.652e-09 4.659e-08
166 REGULATION OF CELLULAR LOCALIZATION 135 1277 1.764e-09 4.946e-08
167 CARTILAGE DEVELOPMENT 31 147 2.38e-09 6.631e-08
168 CELL SUBSTRATE ADHESION 33 164 2.588e-09 7.167e-08
169 REGULATION OF CALCIUM ION TRANSPORT 38 209 3.356e-09 9.239e-08
170 REGULATION OF EPITHELIAL CELL MIGRATION 33 166 3.569e-09 9.769e-08
171 CELLULAR RESPONSE TO HORMONE STIMULUS 72 552 3.887e-09 1.055e-07
172 RESPONSE TO ABIOTIC STIMULUS 113 1024 3.901e-09 1.055e-07
173 MESENCHYMAL CELL DIFFERENTIATION 29 134 4.147e-09 1.115e-07
174 REGULATION OF ERK1 AND ERK2 CASCADE 41 238 4.255e-09 1.138e-07
175 NEGATIVE REGULATION OF TRANSPORT 63 458 4.78e-09 1.271e-07
176 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 25 104 5.014e-09 1.326e-07
177 REGULATION OF OSSIFICATION 34 178 6.087e-09 1.6e-07
178 OSSIFICATION 42 251 6.731e-09 1.759e-07
179 REGULATION OF ORGAN MORPHOGENESIS 41 242 7.02e-09 1.825e-07
180 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 37 207 8.684e-09 2.245e-07
181 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 54 372 9.399e-09 2.416e-07
182 REGULATION OF SECRETION 84 699 9.874e-09 2.511e-07
183 SYSTEM PROCESS 172 1785 9.85e-09 2.511e-07
184 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 28 131 1.024e-08 2.588e-07
185 STRIATED MUSCLE CELL DIFFERENTIATION 33 173 1.051e-08 2.629e-07
186 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 24 100 1.048e-08 2.629e-07
187 TUBE MORPHOGENESIS 49 323 1.082e-08 2.692e-07
188 CELL FATE COMMITMENT 39 227 1.092e-08 2.703e-07
189 REGULATION OF TRANSMEMBRANE TRANSPORT 59 426 1.146e-08 2.822e-07
190 POSITIVE REGULATION OF TRANSPORT 104 936 1.182e-08 2.894e-07
191 REGULATION OF ANATOMICAL STRUCTURE SIZE 63 472 1.54e-08 3.752e-07
192 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 62 465 2.086e-08 5.055e-07
193 CELL MATRIX ADHESION 26 119 2.114e-08 5.097e-07
194 MUSCLE CONTRACTION 39 233 2.294e-08 5.501e-07
195 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 48 321 2.428e-08 5.794e-07
196 REGULATION OF GROWTH 77 633 2.462e-08 5.844e-07
197 REGULATION OF LEUKOCYTE PROLIFERATION 36 206 2.526e-08 5.967e-07
198 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 102 926 2.567e-08 6.033e-07
199 POSITIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 31 162 2.696e-08 6.305e-07
200 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 30 154 2.95e-08 6.829e-07
201 AMEBOIDAL TYPE CELL MIGRATION 30 154 2.95e-08 6.829e-07
202 ENDOTHELIUM DEVELOPMENT 22 90 2.984e-08 6.874e-07
203 NEGATIVE REGULATION OF GROWTH 39 236 3.285e-08 7.531e-07
204 TELENCEPHALON DEVELOPMENT 38 228 3.894e-08 8.882e-07
205 REGULATION OF BODY FLUID LEVELS 65 506 4.033e-08 9.109e-07
206 TISSUE MIGRATION 21 84 4.016e-08 9.109e-07
207 REGULATION OF ION HOMEOSTASIS 35 201 4.321e-08 9.699e-07
208 T CELL DIFFERENTIATION 26 123 4.336e-08 9.699e-07
209 REGULATION OF PROTEIN SECRETION 54 389 4.417e-08 9.834e-07
210 REGULATION OF CYTOKINE PRODUCTION 70 563 4.533e-08 1.004e-06
211 MORPHOGENESIS OF AN EPITHELIUM 55 400 4.607e-08 1.016e-06
212 ENDOTHELIAL CELL MIGRATION 17 57 4.693e-08 1.03e-06
213 NEGATIVE REGULATION OF PHOSPHORYLATION 57 422 4.931e-08 1.077e-06
214 RENAL TUBULE DEVELOPMENT 20 78 5.323e-08 1.157e-06
215 NEPHRON EPITHELIUM DEVELOPMENT 22 93 5.643e-08 1.221e-06
216 CELL JUNCTION ORGANIZATION 33 185 5.752e-08 1.239e-06
217 COGNITION 40 251 6.145e-08 1.318e-06
218 PLATELET ACTIVATION 28 142 6.454e-08 1.378e-06
219 REGULATION OF KINASE ACTIVITY 88 776 6.61e-08 1.404e-06
220 SECOND MESSENGER MEDIATED SIGNALING 30 160 7.251e-08 1.534e-06
221 POSITIVE REGULATION OF CELL CELL ADHESION 39 243 7.382e-08 1.554e-06
222 REGULATION OF CHONDROCYTE DIFFERENTIATION 15 46 7.669e-08 1.607e-06
223 POSITIVE REGULATION OF KINASE ACTIVITY 62 482 7.903e-08 1.649e-06
224 CARDIAC CHAMBER DEVELOPMENT 28 144 8.812e-08 1.829e-06
225 REGULATION OF HEMOPOIESIS 46 314 8.852e-08 1.829e-06
226 EMBRYONIC MORPHOGENESIS 67 539 8.909e-08 1.829e-06
227 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 42 274 8.923e-08 1.829e-06
228 CELL CHEMOTAXIS 30 162 9.673e-08 1.974e-06
229 CYTOKINE MEDIATED SIGNALING PATHWAY 59 452 9.752e-08 1.981e-06
230 POSITIVE REGULATION OF ION TRANSPORT 38 236 9.913e-08 2.006e-06
231 IMMUNE RESPONSE 114 1100 1.039e-07 2.093e-06
232 REGULATION OF RESPONSE TO STRESS 143 1468 1.067e-07 2.14e-06
233 ION HOMEOSTASIS 70 576 1.114e-07 2.225e-06
234 CELL JUNCTION ASSEMBLY 26 129 1.194e-07 2.375e-06
235 GLYCOSPHINGOLIPID BIOSYNTHETIC PROCESS 11 25 1.223e-07 2.421e-06
236 NEGATIVE REGULATION OF CELL DEATH 95 872 1.327e-07 2.616e-06
237 REGULATION OF MUSCLE CONTRACTION 28 147 1.389e-07 2.726e-06
238 ARTERY DEVELOPMENT 19 75 1.406e-07 2.749e-06
239 MEMBRANE DEPOLARIZATION 17 61 1.417e-07 2.759e-06
240 NEGATIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 13 36 1.445e-07 2.799e-06
241 ADENYLATE CYCLASE INHIBITING G PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY 18 68 1.45e-07 2.799e-06
242 REGULATION OF HEART CONTRACTION 36 221 1.59e-07 3.057e-06
243 CELLULAR CHEMICAL HOMEOSTASIS 69 570 1.596e-07 3.057e-06
244 HOMEOSTATIC PROCESS 132 1337 1.631e-07 3.111e-06
245 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 57 437 1.646e-07 3.117e-06
246 LEARNING 26 131 1.648e-07 3.117e-06
247 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 32 184 1.669e-07 3.143e-06
248 CELLULAR RESPONSE TO ACID CHEMICAL 31 175 1.692e-07 3.171e-06
249 RESPONSE TO OXIDATIVE STRESS 49 352 1.697e-07 3.171e-06
250 HEMOSTASIS 45 311 1.756e-07 3.269e-06
251 CARDIAC MUSCLE TISSUE DEVELOPMENT 27 140 1.775e-07 3.291e-06
252 SENSORY ORGAN DEVELOPMENT 62 493 1.784e-07 3.294e-06
253 AMINOGLYCAN BIOSYNTHETIC PROCESS 23 107 1.866e-07 3.42e-06
254 REGULATION OF LEUKOCYTE DIFFERENTIATION 37 232 1.867e-07 3.42e-06
255 MULTI MULTICELLULAR ORGANISM PROCESS 35 213 1.895e-07 3.458e-06
256 DIVALENT INORGANIC CATION HOMEOSTASIS 48 343 1.927e-07 3.503e-06
257 NEGATIVE REGULATION OF CELL ADHESION 36 223 2.001e-07 3.623e-06
258 REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 21 92 2.159e-07 3.894e-06
259 REGULATION OF AXONOGENESIS 30 168 2.222e-07 3.992e-06
260 CELL PROLIFERATION 77 672 2.951e-07 5.28e-06
261 CELL GROWTH 26 135 3.069e-07 5.471e-06
262 REGULATION OF RESPONSE TO WOUNDING 54 413 3.211e-07 5.655e-06
263 REGULATION OF PROTEIN LOCALIZATION 100 950 3.192e-07 5.655e-06
264 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 22 102 3.221e-07 5.655e-06
265 REGULATION OF CATION TRANSMEMBRANE TRANSPORT 34 208 3.205e-07 5.655e-06
266 REGULATION OF CHEMOTAXIS 31 180 3.241e-07 5.669e-06
267 POSITIVE REGULATION OF LEUKOCYTE PROLIFERATION 26 136 3.569e-07 6.22e-06
268 CELLULAR HOMEOSTASIS 77 676 3.742e-07 6.496e-06
269 POSITIVE REGULATION OF ERK1 AND ERK2 CASCADE 30 172 3.77e-07 6.52e-06
270 CELLULAR RESPONSE TO BIOTIC STIMULUS 29 163 3.814e-07 6.573e-06
271 REGULATION OF MUSCLE TISSUE DEVELOPMENT 22 103 3.853e-07 6.616e-06
272 EMBRYO DEVELOPMENT 95 894 4.165e-07 7.125e-06
273 POSITIVE REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 13 39 4.247e-07 7.239e-06
274 REGULATION OF CELL SUBSTRATE ADHESION 30 173 4.289e-07 7.26e-06
275 SKELETAL SYSTEM MORPHOGENESIS 33 201 4.291e-07 7.26e-06
276 CARDIAC CHAMBER MORPHOGENESIS 22 104 4.598e-07 7.752e-06
277 CARDIOCYTE DIFFERENTIATION 21 96 4.627e-07 7.773e-06
278 MODULATION OF SYNAPTIC TRANSMISSION 43 301 4.683e-07 7.838e-06
279 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 26 138 4.803e-07 8.009e-06
280 MEMBRANE DEPOLARIZATION DURING CARDIAC MUSCLE CELL ACTION POTENTIAL 8 14 5.371e-07 8.925e-06
281 GLIOGENESIS 30 175 5.532e-07 9.161e-06
282 NEGATIVE REGULATION OF CELL DEVELOPMENT 43 303 5.625e-07 9.281e-06
283 REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 34 213 5.673e-07 9.295e-06
284 AMINOGLYCAN METABOLIC PROCESS 29 166 5.666e-07 9.295e-06
285 REGULATION OF CELLULAR COMPONENT BIOGENESIS 84 767 5.812e-07 9.489e-06
286 MESONEPHRIC TUBULE MORPHOGENESIS 15 53 6.154e-07 1.001e-05
287 NEGATIVE REGULATION OF CELL ACTIVATION 28 158 6.544e-07 1.057e-05
288 RESPONSE TO PURINE CONTAINING COMPOUND 28 158 6.544e-07 1.057e-05
289 ORGAN GROWTH 17 68 7.779e-07 1.252e-05
290 REGULATION OF IMMUNE RESPONSE 91 858 7.989e-07 1.282e-05
291 REGULATION OF BLOOD PRESSURE 29 169 8.323e-07 1.331e-05
292 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 23 116 8.546e-07 1.362e-05
293 MUCOPOLYSACCHARIDE METABOLIC PROCESS 22 108 9.097e-07 1.445e-05
294 KIDNEY EPITHELIUM DEVELOPMENT 24 125 9.178e-07 1.453e-05
295 EPITHELIAL CELL DIFFERENTIATION 60 495 9.814e-07 1.548e-05
296 SECRETION 68 588 1.053e-06 1.655e-05
297 DEVELOPMENTAL CELL GROWTH 18 77 1.08e-06 1.693e-05
298 LEUKOCYTE MIGRATION 38 259 1.105e-06 1.72e-05
299 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 28 162 1.103e-06 1.72e-05
300 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 26 144 1.125e-06 1.74e-05
301 PALLIUM DEVELOPMENT 27 153 1.123e-06 1.74e-05
302 ACTIN FILAMENT BASED MOVEMENT 20 93 1.15e-06 1.749e-05
303 POSITIVE REGULATION OF CELL ACTIVATION 43 311 1.146e-06 1.749e-05
304 MULTICELLULAR ORGANISM METABOLIC PROCESS 20 93 1.15e-06 1.749e-05
305 NEGATIVE REGULATION OF SECRETION 32 200 1.147e-06 1.749e-05
306 HEART PROCESS 19 85 1.138e-06 1.749e-05
307 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 31 191 1.226e-06 1.859e-05
308 REGULATION OF SMOOTH MUSCLE CELL MIGRATION 14 49 1.283e-06 1.938e-05
309 SYNAPSE ORGANIZATION 26 145 1.29e-06 1.942e-05
310 REGULATION OF MONOCYTE CHEMOTAXIS 9 20 1.409e-06 2.114e-05
311 PROTEIN PHOSPHORYLATION 97 944 1.422e-06 2.127e-05
312 REGULATION OF HORMONE LEVELS 58 478 1.435e-06 2.134e-05
313 MUSCLE CELL DEVELOPMENT 24 128 1.433e-06 2.134e-05
314 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 176 1977 1.457e-06 2.159e-05
315 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 21 103 1.576e-06 2.321e-05
316 REGULATION OF MUSCLE ORGAN DEVELOPMENT 21 103 1.576e-06 2.321e-05
317 REGULATION OF NEUROTRANSMITTER TRANSPORT 16 64 1.636e-06 2.401e-05
318 CARDIAC MUSCLE CELL ACTION POTENTIAL 12 37 1.653e-06 2.412e-05
319 AXON EXTENSION 12 37 1.653e-06 2.412e-05
320 BONE DEVELOPMENT 27 156 1.659e-06 2.413e-05
321 REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 35 233 1.673e-06 2.426e-05
322 REGULATION OF OSTEOBLAST DIFFERENTIATION 22 112 1.734e-06 2.497e-05
323 CELLULAR RESPONSE TO PEPTIDE 39 274 1.732e-06 2.497e-05
324 POSITIVE REGULATION OF CYTOKINE PRODUCTION 48 370 1.798e-06 2.582e-05
325 ENDOTHELIAL CELL DIFFERENTIATION 17 72 1.844e-06 2.633e-05
326 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 23 121 1.845e-06 2.633e-05
327 POSITIVE REGULATION OF IMMUNE RESPONSE 65 563 1.925e-06 2.739e-05
328 RESPONSE TO ORGANOPHOSPHORUS 25 139 1.936e-06 2.746e-05
329 BRANCHING INVOLVED IN URETERIC BUD MORPHOGENESIS 13 44 2.017e-06 2.852e-05
330 REGULATION OF STEM CELL DIFFERENTIATION 22 113 2.026e-06 2.856e-05
331 REGULATION OF NEUROTRANSMITTER SECRETION 14 51 2.179e-06 3.063e-05
332 CEREBRAL CORTEX DEVELOPMENT 21 105 2.186e-06 3.064e-05
333 REGULATION OF LEUKOCYTE MIGRATION 26 149 2.194e-06 3.066e-05
334 RESPONSE TO ALCOHOL 47 362 2.245e-06 3.128e-05
335 REGULATION OF MAP KINASE ACTIVITY 43 319 2.259e-06 3.137e-05
336 COLLAGEN FIBRIL ORGANIZATION 12 38 2.278e-06 3.154e-05
337 SIALYLATION 9 21 2.326e-06 3.212e-05
338 MULTICELLULAR ORGANISMAL SIGNALING 23 123 2.476e-06 3.408e-05
339 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 20 98 2.732e-06 3.75e-05
340 CARDIAC MUSCLE CELL DIFFERENTIATION 17 74 2.767e-06 3.775e-05
341 ACTIN MEDIATED CELL CONTRACTION 17 74 2.767e-06 3.775e-05
342 REGULATION OF SEQUESTERING OF CALCIUM ION 21 107 3.005e-06 4.076e-05
343 REGULATION OF T CELL DIFFERENTIATION 21 107 3.005e-06 4.076e-05
344 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 32 209 3.041e-06 4.113e-05
345 MEMBRANE DEPOLARIZATION DURING ACTION POTENTIAL 12 39 3.101e-06 4.183e-05
346 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL 17 75 3.369e-06 4.517e-05
347 NEURAL CREST CELL DIFFERENTIATION 17 75 3.369e-06 4.517e-05
348 CHONDROCYTE DIFFERENTIATION 15 60 3.444e-06 4.605e-05
349 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 14 53 3.597e-06 4.796e-05
350 REGULATION OF INTRACELLULAR TRANSPORT 69 621 3.631e-06 4.827e-05
351 REGULATION OF CYTOPLASMIC TRANSPORT 57 481 3.698e-06 4.902e-05
352 CELL CELL SIGNALING INVOLVED IN CARDIAC CONDUCTION 9 22 3.716e-06 4.912e-05
353 REGULATION OF NUCLEOTIDE METABOLIC PROCESS 32 211 3.74e-06 4.93e-05
354 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 37 262 3.816e-06 5.016e-05
355 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 16 68 3.87e-06 5.073e-05
356 EYE DEVELOPMENT 43 326 3.988e-06 5.212e-05
357 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 18 84 4.118e-06 5.368e-05
358 REGULATION OF BMP SIGNALING PATHWAY 17 77 4.937e-06 6.417e-05
359 SECRETION BY CELL 57 486 5.08e-06 6.584e-05
360 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 58 498 5.222e-06 6.75e-05
361 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 26 156 5.271e-06 6.794e-05
362 RESPONSE TO ACID CHEMICAL 42 319 5.387e-06 6.924e-05
363 CELL SUBSTRATE JUNCTION ASSEMBLY 12 41 5.566e-06 7.134e-05
364 ATRIAL SEPTUM DEVELOPMENT 8 18 6.225e-06 7.935e-05
365 GANGLIOSIDE BIOSYNTHETIC PROCESS 8 18 6.225e-06 7.935e-05
366 RESPONSE TO MONOAMINE 11 35 6.357e-06 8.082e-05
367 CARDIAC MUSCLE CELL CONTRACTION 10 29 6.578e-06 8.34e-05
368 ION TRANSPORT 119 1262 6.614e-06 8.362e-05
369 RESPONSE TO CAMP 20 104 7.093e-06 8.944e-05
370 MULTICELLULAR ORGANISMAL MACROMOLECULE METABOLIC PROCESS 17 79 7.133e-06 8.97e-05
371 GLOMERULUS DEVELOPMENT 13 49 7.581e-06 9.508e-05
372 REGULATION OF STEM CELL PROLIFERATION 18 88 8.23e-06 0.0001029
373 REGULATION OF LYMPHOCYTE DIFFERENTIATION 23 132 8.521e-06 0.0001063
374 GLAND MORPHOGENESIS 19 97 9.043e-06 0.0001125
375 CYCLIC NUCLEOTIDE METABOLIC PROCESS 14 57 9.072e-06 0.0001126
376 ATRIAL SEPTUM MORPHOGENESIS 7 14 9.264e-06 0.0001143
377 POSITIVE REGULATION OF TYPE 2 IMMUNE RESPONSE 7 14 9.264e-06 0.0001143
378 RESPONSE TO PEPTIDE 49 404 9.36e-06 0.0001152
379 REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 13 50 9.655e-06 0.0001176
380 REGULATION OF HORMONE SECRETION 36 262 9.588e-06 0.0001176
381 CELLULAR RESPONSE TO CAMP 13 50 9.655e-06 0.0001176
382 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 13 50 9.655e-06 0.0001176
383 REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 15 65 9.959e-06 0.000121
384 REGULATION OF MUSCLE CELL DIFFERENTIATION 25 152 1.009e-05 0.0001222
385 RESPONSE TO REACTIVE OXYGEN SPECIES 29 191 1.026e-05 0.000124
386 REGULATION OF ORGAN GROWTH 16 73 1.029e-05 0.000124
387 METAL ION TRANSPORT 64 582 1.134e-05 0.000136
388 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 77 740 1.132e-05 0.000136
389 CELL COMMUNICATION INVOLVED IN CARDIAC CONDUCTION 11 37 1.159e-05 0.0001386
390 VASCULAR PROCESS IN CIRCULATORY SYSTEM 26 163 1.19e-05 0.000142
391 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 137 1517 1.196e-05 0.0001422
392 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 24 144 1.198e-05 0.0001422
393 KIDNEY MORPHOGENESIS 17 82 1.208e-05 0.0001426
394 CARDIAC CONDUCTION 17 82 1.208e-05 0.0001426
395 ARTERY MORPHOGENESIS 13 51 1.221e-05 0.0001435
396 POSITIVE REGULATION OF ALPHA BETA T CELL ACTIVATION 13 51 1.221e-05 0.0001435
397 NEGATIVE REGULATION OF PROTEIN SECRETION 20 108 1.28e-05 0.00015
398 REGULATION OF WOUND HEALING 22 126 1.284e-05 0.0001501
399 CARDIAC ATRIUM DEVELOPMENT 10 31 1.296e-05 0.0001504
400 REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION 10 31 1.296e-05 0.0001504
401 REGULATION OF PLATELET ACTIVATION 10 31 1.296e-05 0.0001504
402 REGULATION OF CYCLIC NUCLEOTIDE METABOLIC PROCESS 25 155 1.43e-05 0.0001651
403 PROTEOGLYCAN METABOLIC PROCESS 17 83 1.43e-05 0.0001651
404 SENSORY PERCEPTION OF PAIN 16 75 1.48e-05 0.0001705
405 DIVALENT INORGANIC CATION TRANSPORT 36 268 1.59e-05 0.0001826
406 SPROUTING ANGIOGENESIS 12 45 1.601e-05 0.0001831
407 NEGATIVE REGULATION OF RESPONSE TO WOUNDING 25 156 1.602e-05 0.0001831
408 CELL MIGRATION INVOLVED IN SPROUTING ANGIOGENESIS 7 15 1.642e-05 0.0001872
409 REGULATION OF EXTENT OF CELL GROWTH 19 101 1.658e-05 0.0001886
410 NEURON MIGRATION 20 110 1.697e-05 0.0001926
411 REGULATION OF SMOOTH MUSCLE CONTRACTION 14 60 1.711e-05 0.0001937
412 REGULATION OF CALCIUM MEDIATED SIGNALING 16 76 1.766e-05 0.0001992
413 REGULATION OF ALPHA BETA T CELL ACTIVATION 15 68 1.781e-05 0.0001992
414 REGULATION OF CELL JUNCTION ASSEMBLY 15 68 1.781e-05 0.0001992
415 REGULATION OF ACTIN FILAMENT BASED MOVEMENT 10 32 1.779e-05 0.0001992
416 ADIPOSE TISSUE DEVELOPMENT 10 32 1.779e-05 0.0001992
417 REGULATION OF TYPE 2 IMMUNE RESPONSE 9 26 1.853e-05 0.0002062
418 GANGLIOSIDE METABOLIC PROCESS 9 26 1.853e-05 0.0002062
419 REGULATION OF CAMP METABOLIC PROCESS 22 129 1.884e-05 0.0002092
420 RENAL SYSTEM PROCESS 19 102 1.918e-05 0.0002125
421 CARDIAC SEPTUM DEVELOPMENT 17 85 1.988e-05 0.0002192
422 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 48 404 1.983e-05 0.0002192
423 REGULATION OF TRANSPORTER ACTIVITY 29 198 2.064e-05 0.000227
424 ACTOMYOSIN STRUCTURE ORGANIZATION 16 77 2.1e-05 0.0002304
425 GLYCOSPHINGOLIPID METABOLIC PROCESS 15 69 2.144e-05 0.0002331
426 ACTION POTENTIAL 18 94 2.136e-05 0.0002331
427 NEGATIVE REGULATION OF OSSIFICATION 15 69 2.144e-05 0.0002331
428 POSITIVE REGULATION OF AXONOGENESIS 15 69 2.144e-05 0.0002331
429 REGULATION OF CALCIUM ION IMPORT 19 103 2.215e-05 0.0002402
430 GLAND DEVELOPMENT 47 395 2.322e-05 0.0002512
431 NEURON RECOGNITION 10 33 2.408e-05 0.0002594
432 RESPONSE TO VITAMIN D 10 33 2.408e-05 0.0002594
433 POSITIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 22 131 2.415e-05 0.0002595
434 LYMPHOCYTE COSTIMULATION 16 78 2.488e-05 0.0002667
435 NEGATIVE REGULATION OF CELL GROWTH 26 170 2.54e-05 0.0002712
436 FOREBRAIN CELL MIGRATION 14 62 2.547e-05 0.0002712
437 RESPONSE TO DRUG 50 431 2.546e-05 0.0002712
438 REGULATION OF CARDIAC MUSCLE CELL CONTRACTION 9 27 2.623e-05 0.0002787
439 CELL DEATH 96 1001 2.776e-05 0.0002942
440 REGULATION OF ENDOTHELIAL CELL MIGRATION 20 114 2.917e-05 0.0003085
441 REGULATION OF KIDNEY DEVELOPMENT 13 55 2.937e-05 0.0003087
442 REGULATION OF POSTSYNAPTIC MEMBRANE POTENTIAL 13 55 2.937e-05 0.0003087
443 BONE MORPHOGENESIS 16 79 2.939e-05 0.0003087
444 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 24 152 3.018e-05 0.0003163
445 POSITIVE REGULATION OF PURINE NUCLEOTIDE METABOLIC PROCESS 22 133 3.075e-05 0.0003209
446 POSITIVE REGULATION OF NUCLEOTIDE METABOLIC PROCESS 22 133 3.075e-05 0.0003209
447 NEGATIVE REGULATION OF NUCLEOTIDE METABOLIC PROCESS 14 63 3.086e-05 0.0003212
448 HEART VALVE DEVELOPMENT 10 34 3.219e-05 0.0003344
449 MYOFIBRIL ASSEMBLY 12 48 3.25e-05 0.000336
450 REGULATION OF INTERLEUKIN 2 PRODUCTION 12 48 3.25e-05 0.000336
451 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 24 153 3.369e-05 0.0003476
452 POSITIVE REGULATION OF KIDNEY DEVELOPMENT 11 41 3.387e-05 0.0003479
453 AORTA DEVELOPMENT 11 41 3.387e-05 0.0003479
454 REGULATION OF PEPTIDE TRANSPORT 34 256 3.427e-05 0.0003512
455 POSITIVE REGULATION OF LYMPHOCYTE DIFFERENTIATION 16 80 3.46e-05 0.0003538
456 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 65 616 3.544e-05 0.0003616
457 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 13 56 3.605e-05 0.0003671
458 REGULATION OF SPROUTING ANGIOGENESIS 9 28 3.65e-05 0.0003708
459 REGULATION OF CELL GROWTH 46 391 3.747e-05 0.0003798
460 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 18 98 3.835e-05 0.0003879
461 PLATELET DEGRANULATION 19 107 3.851e-05 0.0003887
462 NEGATIVE REGULATION OF MAPK CASCADE 23 145 4.071e-05 0.0004092
463 ADENYLATE CYCLASE MODULATING G PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY 23 145 4.071e-05 0.0004092
464 POSITIVE REGULATION OF HOMEOSTATIC PROCESS 30 216 4.199e-05 0.000421
465 NEGATIVE REGULATION OF MAP KINASE ACTIVITY 15 73 4.334e-05 0.000429
466 POSITIVE REGULATION OF STAT CASCADE 15 73 4.334e-05 0.000429
467 CELLULAR RESPONSE TO KETONE 15 73 4.334e-05 0.000429
468 REGULATION OF HEART GROWTH 11 42 4.328e-05 0.000429
469 POSITIVE REGULATION OF JAK STAT CASCADE 15 73 4.334e-05 0.000429
470 MESONEPHROS DEVELOPMENT 17 90 4.309e-05 0.000429
471 STRIATED MUSCLE CONTRACTION 18 99 4.414e-05 0.0004361
472 REGULATION OF PLATELET AGGREGATION 7 17 4.434e-05 0.0004371
473 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 25 166 4.688e-05 0.0004612
474 INTEGRIN MEDIATED SIGNALING PATHWAY 16 82 4.753e-05 0.0004656
475 PATTERN SPECIFICATION PROCESS 48 418 4.749e-05 0.0004656
476 SKELETAL MUSCLE ORGAN DEVELOPMENT 22 137 4.903e-05 0.0004793
477 INFLAMMATORY RESPONSE 51 454 4.978e-05 0.0004856
478 POSITIVE REGULATION OF CARTILAGE DEVELOPMENT 9 29 4.996e-05 0.0004863
479 REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 19 109 5.018e-05 0.0004874
480 REGULATION OF OSTEOBLAST PROLIFERATION 8 23 5.244e-05 0.0005073
481 RESPONSE TO AUDITORY STIMULUS 8 23 5.244e-05 0.0005073
482 PROTEOGLYCAN BIOSYNTHETIC PROCESS 13 58 5.348e-05 0.0005163
483 NEGATIVE REGULATION OF CELL CELL ADHESION 22 138 5.49e-05 0.0005278
484 CHONDROITIN SULFATE PROTEOGLYCAN METABOLIC PROCESS 11 43 5.486e-05 0.0005278
485 REGULATION OF POTASSIUM ION TRANSPORT 16 83 5.547e-05 0.000532
486 T CELL SELECTION 10 36 5.557e-05 0.000532
487 REGULATION OF PEPTIDE SECRETION 29 209 5.696e-05 0.0005442
488 FORMATION OF PRIMARY GERM LAYER 19 110 5.711e-05 0.0005446
489 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 42 352 5.811e-05 0.0005529
490 CELLULAR RESPONSE TO FATTY ACID 12 51 6.208e-05 0.0005895
491 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 14 67 6.37e-05 0.0006036
492 AGING 34 264 6.425e-05 0.0006076
493 REGULATION OF TRANSFERASE ACTIVITY 90 946 6.621e-05 0.0006249
494 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 27 190 6.694e-05 0.0006305
495 REGULATION OF HEART RATE BY CARDIAC CONDUCTION 9 30 6.738e-05 0.0006334
496 POSITIVE REGULATION OF PROTEIN SECRETION 29 211 6.78e-05 0.0006361
497 POSITIVE REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 7 18 6.86e-05 0.000641
498 CELLULAR RESPONSE TO PROSTAGLANDIN E STIMULUS 7 18 6.86e-05 0.000641
499 EXTRACELLULAR MATRIX DISASSEMBLY 15 76 7.08e-05 0.0006602
500 NEGATIVE REGULATION OF GENE EXPRESSION 131 1493 7.153e-05 0.0006656
501 POSITIVE REGULATION OF ALPHA BETA T CELL DIFFERENTIATION 10 37 7.185e-05 0.0006673
502 RESPONSE TO STEROID HORMONE 54 497 7.43e-05 0.0006874
503 CELLULAR RESPONSE TO PROSTAGLANDIN STIMULUS 8 24 7.431e-05 0.0006874
504 LOCOMOTORY BEHAVIOR 26 181 7.549e-05 0.0006969
505 NEGATIVE REGULATION OF NEURON DEATH 25 171 7.703e-05 0.0007097
506 RESPONSE TO OXYGEN LEVELS 38 311 7.767e-05 0.0007142
507 CATION TRANSPORT 78 796 7.82e-05 0.0007177
508 RESPONSE TO BIOTIC STIMULUS 85 886 7.908e-05 0.0007243
509 ION TRANSMEMBRANE TRANSPORT 80 822 7.972e-05 0.0007288
510 PHOSPHORYLATION 111 1228 8.119e-05 0.0007407
511 REGULATED EXOCYTOSIS 30 224 8.298e-05 0.0007556
512 EMBRYONIC ORGAN MORPHOGENESIS 35 279 8.646e-05 0.0007812
513 NEGATIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 24 162 8.596e-05 0.0007812
514 ENDOCHONDRAL BONE MORPHOGENESIS 11 45 8.614e-05 0.0007812
515 ACTIVATION OF PROTEIN KINASE ACTIVITY 35 279 8.646e-05 0.0007812
516 POSITIVE REGULATION OF T CELL PROLIFERATION 17 95 8.766e-05 0.0007904
517 POSITIVE REGULATION OF INTERLEUKIN 2 PRODUCTION 9 31 8.965e-05 0.0008053
518 REGULATION OF SYNAPTIC VESICLE TRANSPORT 9 31 8.965e-05 0.0008053
519 RESPONSE TO EXTRACELLULAR STIMULUS 49 441 9.115e-05 0.0008172
520 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 31 236 9.186e-05 0.0008219
521 POSITIVE REGULATION OF ORGAN GROWTH 10 38 9.203e-05 0.0008219
522 NEURON PROJECTION EXTENSION 12 53 9.276e-05 0.0008268
523 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 72 724 9.297e-05 0.0008271
524 POSITIVE REGULATION OF HEMOPOIESIS 24 163 9.487e-05 0.0008424
525 MOVEMENT IN ENVIRONMENT OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 16 87 0.0001001 0.0008753
526 ENTRY INTO CELL OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 16 87 0.0001001 0.0008753
527 VIRAL ENTRY INTO HOST CELL 16 87 0.0001001 0.0008753
528 ENTRY INTO OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 16 87 0.0001001 0.0008753
529 MOVEMENT IN HOST ENVIRONMENT 16 87 0.0001001 0.0008753
530 ENTRY INTO HOST 16 87 0.0001001 0.0008753
531 ENTRY INTO HOST CELL 16 87 0.0001001 0.0008753
532 INOSITOL LIPID MEDIATED SIGNALING 20 124 9.975e-05 0.0008753
533 POSITIVE REGULATION OF CHONDROCYTE DIFFERENTIATION 7 19 0.0001027 0.0008965
534 CHONDROITIN SULFATE BIOSYNTHETIC PROCESS 8 25 0.0001032 0.0008994
535 INTERACTION WITH HOST 21 134 0.0001034 0.0008994
536 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 14 70 0.0001053 0.0009124
537 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 14 70 0.0001053 0.0009124
538 RESPONSE TO INTERLEUKIN 1 19 115 0.0001061 0.000918
539 CYCLIC NUCLEOTIDE MEDIATED SIGNALING 11 46 0.0001068 0.0009202
540 REGULATION OF ALPHA BETA T CELL DIFFERENTIATION 11 46 0.0001068 0.0009202
541 POSITIVE REGULATION OF CALCIUM ION TRANSPORT 18 106 0.0001113 0.0009555
542 CARDIAC VENTRICLE DEVELOPMENT 18 106 0.0001113 0.0009555
543 NEGATIVE CHEMOTAXIS 10 39 0.0001168 0.001001
544 ENDOCARDIAL CUSHION DEVELOPMENT 9 32 0.0001178 0.001007
545 POSITIVE REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 6 14 0.0001228 0.001046
546 POSITIVE REGULATION OF SPROUTING ANGIOGENESIS 6 14 0.0001228 0.001046
547 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 27 197 0.0001248 0.001062
548 GLIAL CELL DIFFERENTIATION 21 136 0.0001284 0.00109
549 REGULATION OF NEURON DEATH 32 252 0.0001358 0.001151
550 DEFENSE RESPONSE 110 1231 0.0001377 0.001165
551 POSITIVE REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION 8 26 0.0001409 0.00119
552 CELLULAR RESPONSE TO EXTERNAL STIMULUS 33 264 0.0001455 0.001226
553 NEGATIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 10 40 0.000147 0.001237
554 POSITIVE REGULATION OF CELL SUBSTRATE ADHESION 17 99 0.0001485 0.001247
555 MELANOCYTE DIFFERENTIATION 7 20 0.0001494 0.001252
556 CYTOSKELETON ORGANIZATION 80 838 0.0001498 0.001253
557 METANEPHROS DEVELOPMENT 15 81 0.0001508 0.00126
558 REGULATION OF WNT SIGNALING PATHWAY 37 310 0.0001554 0.001296
559 NEGATIVE REGULATION OF HEMOPOIESIS 20 128 0.0001561 0.001298
560 REGULATION OF PHOSPHOLIPASE ACTIVITY 13 64 0.0001563 0.001298
561 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 30 232 0.000157 0.001302
562 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 11 48 0.000161 0.00133
563 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 11 48 0.000161 0.00133
564 POSITIVE REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 25 179 0.0001621 0.001337
565 EPITHELIAL TO MESENCHYMAL TRANSITION 12 56 0.0001628 0.001341
566 NEGATIVE REGULATION OF CYTOKINE PRODUCTION 28 211 0.0001652 0.001358
567 REGIONALIZATION 37 311 0.0001659 0.001361
568 REGULATION OF CELL SHAPE 21 139 0.0001758 0.00144
569 POSITIVE REGULATION OF SECRETION 42 370 0.0001775 0.001452
570 POSITIVE REGULATION OF SYNAPTIC TRANSMISSION 18 110 0.0001809 0.001477
571 CALCIUM ION TRANSPORT 29 223 0.0001817 0.001481
572 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 45 406 0.0001835 0.001492
573 POSITIVE REGULATION OF HEART GROWTH 8 27 0.0001892 0.001531
574 POSITIVE REGULATION OF CD4 POSITIVE ALPHA BETA T CELL ACTIVATION 8 27 0.0001892 0.001531
575 HETEROTYPIC CELL CELL ADHESION 8 27 0.0001892 0.001531
576 AZOLE TRANSPORT 6 15 0.0001936 0.001564
577 REGULATION OF MESENCHYMAL CELL PROLIFERATION 9 34 0.0001963 0.001575
578 RESPONSE TO PROSTAGLANDIN 9 34 0.0001963 0.001575
579 CAMP METABOLIC PROCESS 9 34 0.0001963 0.001575
580 CARDIAC SEPTUM MORPHOGENESIS 11 49 0.0001958 0.001575
581 REGULATION OF CELLULAR COMPONENT SIZE 39 337 0.0002002 0.0016
582 RESPONSE TO FATTY ACID 15 83 2e-04 0.0016
583 REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION 27 203 0.0002064 0.001647
584 CHONDROCYTE DEVELOPMENT 7 21 0.0002119 0.001675
585 RESPONSE TO KETONE 25 182 0.000211 0.001675
586 CELL AGGREGATION 7 21 0.0002119 0.001675
587 REGULATION OF SYNAPTIC VESICLE EXOCYTOSIS 7 21 0.0002119 0.001675
588 RESPONSE TO VIRUS 31 247 0.000212 0.001675
589 CARTILAGE CONDENSATION 7 21 0.0002119 0.001675
590 REGULATION OF VASOCONSTRICTION 13 66 0.0002162 0.0017
591 REGULATION OF CARDIAC MUSCLE CONTRACTION 13 66 0.0002162 0.0017
592 NEGATIVE REGULATION OF HOMOTYPIC CELL CELL ADHESION 17 102 0.0002158 0.0017
593 G PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY COUPLED TO CYCLIC NUCLEOTIDE SECOND MESSENGER 24 172 0.0002202 0.001728
594 POSITIVE REGULATION OF BLOOD CIRCULATION 16 93 0.000225 0.001763
595 NEGATIVE REGULATION OF BMP SIGNALING PATHWAY 10 42 0.0002272 0.001774
596 MULTI ORGANISM BEHAVIOR 14 75 0.0002272 0.001774
597 REGULATION OF MYELOID CELL DIFFERENTIATION 25 183 0.00023 0.00179
598 REGULATION OF PROTEIN IMPORT 25 183 0.00023 0.00179
599 REGULATION OF DEFENSE RESPONSE 73 759 0.0002314 0.001798
600 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 19 122 0.0002357 0.001828
601 REGULATION OF INFLAMMATORY RESPONSE 35 294 0.0002428 0.00188
602 INORGANIC ION TRANSMEMBRANE TRANSPORT 59 583 0.0002477 0.001915
603 REGULATION OF CYTOKINE BIOSYNTHETIC PROCESS 16 94 0.0002555 0.001965
604 RESPONSE TO BMP 16 94 0.0002555 0.001965
605 CELLULAR RESPONSE TO BMP STIMULUS 16 94 0.0002555 0.001965
606 REGULATION OF ADAPTIVE IMMUNE RESPONSE 19 123 0.0002625 0.002013
607 REGULATION OF STRIATED MUSCLE CELL DIFFERENTIATION 15 85 0.0002626 0.002013
608 VASCULOGENESIS 12 59 0.0002738 0.002096
609 NEGATIVE REGULATION OF MOLECULAR FUNCTION 97 1079 0.0002775 0.00212
610 CERAMIDE BIOSYNTHETIC PROCESS 10 43 0.0002795 0.002132
611 NEURAL CREST CELL MIGRATION 11 51 0.0002849 0.002166
612 NEGATIVE REGULATION OF CHEMOTAXIS 11 51 0.0002849 0.002166
613 NEGATIVE REGULATION OF MUSCLE CONTRACTION 7 22 0.0002939 0.002209
614 NEGATIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION 6 16 0.0002933 0.002209
615 POSITIVE REGULATION OF INTERLEUKIN 4 PRODUCTION 7 22 0.0002939 0.002209
616 PROTEIN LOCALIZATION TO CELL SURFACE 7 22 0.0002939 0.002209
617 RETINA VASCULATURE DEVELOPMENT IN CAMERA TYPE EYE 6 16 0.0002933 0.002209
618 RESPONSE TO EPINEPHRINE 6 16 0.0002933 0.002209
619 CELLULAR RESPONSE TO INTERLEUKIN 6 7 22 0.0002939 0.002209
620 NERVE DEVELOPMENT 13 68 0.0002949 0.002213
621 RESPIRATORY SYSTEM DEVELOPMENT 26 197 0.0003033 0.002272
622 GASTRULATION 22 155 0.0003104 0.002322
623 POSITIVE REGULATION OF AXON EXTENSION 9 36 0.0003143 0.002343
624 RHYTHMIC PROCESS 35 298 0.0003142 0.002343
625 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 18 115 0.0003194 0.002378
626 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 12 60 0.0003228 0.0024
627 NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS 20 135 0.0003236 0.002402
628 REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 8 29 0.0003266 0.002416
629 MUSCLE ADAPTATION 8 29 0.0003266 0.002416
630 REGULATION OF LEUKOCYTE CHEMOTAXIS 16 96 0.0003273 0.002417
631 REGULATION OF T HELPER 2 CELL DIFFERENTIATION 5 11 0.0003375 0.002489
632 POSITIVE REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 11 52 0.0003409 0.002502
633 POSITIVE REGULATION OF IMMUNE EFFECTOR PROCESS 22 156 0.0003402 0.002502
634 POSITIVE REGULATION OF STRIATED MUSCLE CELL DIFFERENTIATION 11 52 0.0003409 0.002502
635 PERIPHERAL NERVOUS SYSTEM DEVELOPMENT 13 69 0.0003426 0.00251
636 RESPONSE TO BACTERIUM 54 528 0.0003454 0.002522
637 ADAPTIVE IMMUNE RESPONSE 34 288 0.0003455 0.002522
638 FAT CELL DIFFERENTIATION 17 106 0.0003458 0.002522
639 EMBRYONIC ORGAN DEVELOPMENT 44 406 0.0003518 0.002562
640 RESPONSE TO INORGANIC SUBSTANCE 50 479 0.0003524 0.002562
641 NEGATIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 20 136 0.0003573 0.002594
642 OSTEOBLAST DIFFERENTIATION 19 126 0.0003596 0.002606
643 REGULATION OF INTERFERON GAMMA PRODUCTION 16 97 0.0003693 0.002669
644 POSITIVE REGULATION OF CATION TRANSMEMBRANE TRANSPORT 16 97 0.0003693 0.002669
645 REGULATION OF T CELL PROLIFERATION 21 147 0.000385 0.002777
646 OVULATION CYCLE PROCESS 15 88 0.0003878 0.002793
647 CORONARY VASCULATURE DEVELOPMENT 9 37 0.0003922 0.002812
648 GLIAL CELL MIGRATION 9 37 0.0003922 0.002812
649 CAMP MEDIATED SIGNALING 9 37 0.0003922 0.002812
650 REGULATION OF RECEPTOR ACTIVITY 18 117 0.0003965 0.002834
651 LEUKOCYTE CHEMOTAXIS 18 117 0.0003965 0.002834
652 NEGATIVE REGULATION OF ION TRANSPORT 19 127 0.0003982 0.002842
653 REGULATION OF METANEPHROS DEVELOPMENT 7 23 0.0003995 0.002842
654 INNERVATION 7 23 0.0003995 0.002842
655 REGULATION OF NITRIC OXIDE BIOSYNTHETIC PROCESS 11 53 0.0004059 0.002884
656 PROTEIN DEPHOSPHORYLATION 25 190 0.000411 0.002915
657 SMOOTH MUSCLE CONTRACTION 10 45 0.0004143 0.002921
658 REGULATION OF PLASMA LIPOPROTEIN PARTICLE LEVELS 10 45 0.0004143 0.002921
659 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 49 470 0.0004132 0.002921
660 REGULATION OF ALCOHOL BIOSYNTHETIC PROCESS 10 45 0.0004143 0.002921
661 MEMORY 16 98 0.0004159 0.002928
662 MEMBRANE BIOGENESIS 8 30 0.0004208 0.002944
663 CHONDROITIN SULFATE PROTEOGLYCAN BIOSYNTHETIC PROCESS 8 30 0.0004208 0.002944
664 POSITIVE REGULATION OF SMOOTH MUSCLE CONTRACTION 8 30 0.0004208 0.002944
665 REGULATION OF MEMBRANE REPOLARIZATION 8 30 0.0004208 0.002944
666 NEGATIVE REGULATION OF PLATELET ACTIVATION 6 17 0.0004291 0.002984
667 REGULATION OF RECEPTOR BINDING 6 17 0.0004291 0.002984
668 NEGATIVE REGULATION OF ANOIKIS 6 17 0.0004291 0.002984
669 MATURE B CELL DIFFERENTIATION 6 17 0.0004291 0.002984
670 POSITIVE REGULATION OF CAMP METABOLIC PROCESS 15 89 0.0004396 0.003048
671 POST EMBRYONIC DEVELOPMENT 15 89 0.0004396 0.003048
672 NEGATIVE REGULATION OF SYNAPTIC TRANSMISSION 12 62 0.0004433 0.003065
673 CARDIAC VENTRICLE MORPHOGENESIS 12 62 0.0004433 0.003065
674 REGULATION OF CYTOKINE SECRETION 21 149 0.000463 0.003197
675 SYNAPTIC SIGNALING 45 424 0.0004776 0.003287
676 REGULATION OF IMMUNE EFFECTOR PROCESS 45 424 0.0004776 0.003287
677 REGULATION OF NEURON APOPTOTIC PROCESS 25 192 0.0004817 0.00331
678 POSITIVE REGULATION OF CYCLIC NUCLEOTIDE METABOLIC PROCESS 17 109 0.0004834 0.003317
679 CELLULAR RESPONSE TO GLUCAGON STIMULUS 9 38 0.0004853 0.003321
680 REGULATION OF CD4 POSITIVE ALPHA BETA T CELL ACTIVATION 9 38 0.0004853 0.003321
681 REGULATION OF MUSCLE ADAPTATION 12 63 0.0005166 0.00353
682 BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 7 24 0.0005334 0.003639
683 REGULATION OF INTERLEUKIN 4 PRODUCTION 8 31 0.000536 0.003651
684 NEURON PROJECTION EXTENSION INVOLVED IN NEURON PROJECTION GUIDANCE 5 12 0.0005485 0.003694
685 AXON EXTENSION INVOLVED IN AXON GUIDANCE 5 12 0.0005485 0.003694
686 HEMATOPOIETIC STEM CELL DIFFERENTIATION 5 12 0.0005485 0.003694
687 REGULATION OF CELL SIZE 23 172 0.0005464 0.003694
688 POSITIVE REGULATION OF GROWTH 29 238 0.0005458 0.003694
689 CELL ADHESION MEDIATED BY INTEGRIN 5 12 0.0005485 0.003694
690 MECHANOSENSORY BEHAVIOR 5 12 0.0005485 0.003694
691 POSITIVE REGULATION OF INTERLEUKIN 2 BIOSYNTHETIC PROCESS 5 12 0.0005485 0.003694
692 ACTIVATION OF IMMUNE RESPONSE 45 427 0.0005552 0.003733
693 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 27 216 0.000561 0.003767
694 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 34 296 0.0005695 0.003819
695 REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 16 101 0.0005872 0.003931
696 NEGATIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 14 82 0.0005895 0.003941
697 POSITIVE REGULATION OF TRANSMEMBRANE TRANSPORT 19 131 0.0005912 0.003945
698 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 60 616 0.0005917 0.003945
699 REGULATION OF PHOSPHOLIPASE C ACTIVITY 9 39 0.0005959 0.003961
700 EMBRYO IMPLANTATION 9 39 0.0005959 0.003961
701 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 17 111 0.0005993 0.003972
702 POSITIVE REGULATION OF GLIOGENESIS 10 47 0.0005993 0.003972
703 CELLULAR RESPONSE TO OXIDATIVE STRESS 24 184 0.0006031 0.003992
704 REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 13 73 0.0006045 0.003996
705 ANTIGEN RECEPTOR MEDIATED SIGNALING PATHWAY 25 195 0.0006076 0.00401
706 POSITIVE REGULATION OF T HELPER CELL DIFFERENTIATION 6 18 0.0006093 0.004016
707 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 55 554 0.0006289 0.004136
708 DEPHOSPHORYLATION 33 286 0.0006293 0.004136
709 EXOCYTOSIS 35 310 0.000653 0.004286
710 LOCALIZATION WITHIN MEMBRANE 18 122 0.0006628 0.004344
711 REGULATION OF DENDRITIC SPINE DEVELOPMENT 11 56 0.0006663 0.00436
712 PHOSPHOLIPASE C ACTIVATING G PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY 14 83 0.0006685 0.004369
713 REGULATION OF ORGAN FORMATION 8 32 0.0006754 0.004389
714 NEGATIVE REGULATION OF POTASSIUM ION TRANSPORT 8 32 0.0006754 0.004389
715 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 8 32 0.0006754 0.004389
716 NEGATIVE REGULATION OF SIGNAL TRANSDUCTION IN ABSENCE OF LIGAND 8 32 0.0006754 0.004389
717 NEGATIVE REGULATION OF HORMONE SECRETION 13 74 0.0006916 0.004476
718 CELL CELL JUNCTION ASSEMBLY 13 74 0.0006916 0.004476
719 NEGATIVE REGULATION OF INTRACELLULAR TRANSPORT 20 143 0.0006906 0.004476
720 REGULATION OF CHEMOKINE PRODUCTION 12 65 0.0006938 0.004478
721 POSITIVE REGULATION OF INTERFERON GAMMA PRODUCTION 12 65 0.0006938 0.004478
722 RESPONSE TO PROSTAGLANDIN E 7 25 0.0007006 0.00449
723 MEMBRANE ASSEMBLY 7 25 0.0007006 0.00449
724 POSTSYNAPTIC MEMBRANE ORGANIZATION 7 25 0.0007006 0.00449
725 HOMEOSTASIS OF NUMBER OF CELLS 23 175 0.0006976 0.00449
726 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL BY SARCOPLASMIC RETICULUM 7 25 0.0007006 0.00449
727 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 25 197 0.0007067 0.004523
728 POSITIVE REGULATION OF ADENYLATE CYCLASE ACTIVITY 10 48 0.0007146 0.004567
729 REPRODUCTIVE SYSTEM DEVELOPMENT 43 408 0.0007277 0.004645
730 OVULATION CYCLE 17 113 0.0007383 0.004706
731 REGULATION OF SYSTEMIC ARTERIAL BLOOD PRESSURE 14 84 0.0007563 0.004808
732 TRANSMEMBRANE TRANSPORT 96 1098 0.0007558 0.004808
733 REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 13 75 0.000789 0.005008
734 MESODERM MORPHOGENESIS 12 66 8e-04 0.005071
735 REGULATION OF INTERLEUKIN 6 PRODUCTION 16 104 0.0008155 0.005163
736 FIBRIL ORGANIZATION 6 19 0.0008431 0.005292
737 PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 5 13 0.000845 0.005292
738 KIDNEY VASCULATURE DEVELOPMENT 6 19 0.0008431 0.005292
739 PERIPHERAL NERVOUS SYSTEM NEURON DIFFERENTIATION 5 13 0.000845 0.005292
740 CARDIOBLAST DIFFERENTIATION 5 13 0.000845 0.005292
741 PERIPHERAL NERVOUS SYSTEM NEURON DEVELOPMENT 5 13 0.000845 0.005292
742 RENAL SYSTEM VASCULATURE DEVELOPMENT 6 19 0.0008431 0.005292
743 GLIAL CELL FATE COMMITMENT 5 13 0.000845 0.005292
744 REGULATION OF TOLL LIKE RECEPTOR SIGNALING PATHWAY 10 49 0.0008476 0.005294
745 POSITIVE REGULATION OF CHEMOKINE PRODUCTION 10 49 0.0008476 0.005294
746 IMMUNE EFFECTOR PROCESS 49 486 0.0008698 0.005425
747 REGULATION OF ANTIGEN RECEPTOR MEDIATED SIGNALING PATHWAY 9 41 0.0008789 0.005475
748 REGULATION OF T HELPER CELL DIFFERENTIATION 7 26 0.0009069 0.005606
749 NEGATIVE REGULATION OF WOUND HEALING 11 58 0.0009073 0.005606
750 NEGATIVE REGULATION OF CARTILAGE DEVELOPMENT 7 26 0.0009069 0.005606
751 RESPONSE TO INTERLEUKIN 6 7 26 0.0009069 0.005606
752 POSITIVE REGULATION OF CYTOKINE BIOSYNTHETIC PROCESS 11 58 0.0009073 0.005606
753 REGULATION OF P38MAPK CASCADE 7 26 0.0009069 0.005606
754 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 12 67 0.0009193 0.005673
755 POSITIVE REGULATION OF DEFENSE RESPONSE 39 364 0.0009215 0.005679
756 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 58 602 0.000942 0.005798
757 REGULATION OF NEUROTRANSMITTER LEVELS 24 190 0.000955 0.00587
758 REGULATION OF HEART RATE 14 86 0.0009614 0.005894
759 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 14 86 0.0009614 0.005894
760 GLYCOPROTEIN METABOLIC PROCESS 38 353 0.0009754 0.005964
761 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 18 126 0.0009751 0.005964
762 REGULATION OF SKELETAL MUSCLE TISSUE DEVELOPMENT 10 50 0.001 0.006076
763 REGULATION OF ADHERENS JUNCTION ORGANIZATION 10 50 0.001 0.006076
764 STAT CASCADE 10 50 0.001 0.006076
765 JAK STAT CASCADE 10 50 0.001 0.006076
766 POSITIVE REGULATION OF CYTOKINE SECRETION 15 96 0.0009959 0.006076
767 SPINAL CORD DEVELOPMENT 16 106 0.001006 0.006106
768 RESPONSE TO NUTRIENT 24 191 0.001028 0.00623
769 RESPONSE TO FLUID SHEAR STRESS 8 34 0.001041 0.006285
770 POSITIVE REGULATION OF SODIUM ION TRANSPORT 8 34 0.001041 0.006285
771 CYCLIC NUCLEOTIDE BIOSYNTHETIC PROCESS 8 34 0.001041 0.006285
772 REGULATION OF TYROSINE PHOSPHORYLATION OF STAT PROTEIN 12 68 0.001053 0.006347
773 NEGATIVE REGULATION OF CYCLIC NUCLEOTIDE METABOLIC PROCESS 9 42 0.001057 0.00636
774 TISSUE REMODELING 14 87 0.00108 0.006494
775 CALCIUM ION TRANSMEMBRANE TRANSPORT 21 159 0.001095 0.006573
776 REGULATION OF AUTOPHAGY 29 249 0.001125 0.006748
777 NEGATIVE REGULATION OF CELL JUNCTION ASSEMBLY 6 20 0.00114 0.006794
778 RESPONSE TO PROTOZOAN 6 20 0.00114 0.006794
779 RELAXATION OF MUSCLE 6 20 0.00114 0.006794
780 PARTURITION 6 20 0.00114 0.006794
781 NEGATIVE REGULATION OF ANTIGEN RECEPTOR MEDIATED SIGNALING PATHWAY 6 20 0.00114 0.006794
782 SARCOMERE ORGANIZATION 7 27 0.001158 0.006864
783 CALCIUM DEPENDENT CELL CELL ADHESION VIA PLASMA MEMBRANE CELL ADHESION MOLECULES 7 27 0.001158 0.006864
784 SUBSTRATE DEPENDENT CELL MIGRATION 7 27 0.001158 0.006864
785 AXIS ELONGATION 7 27 0.001158 0.006864
786 NEGATIVE REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 10 51 0.001175 0.006946
787 NEGATIVE REGULATION OF CALCIUM ION TRANSPORT 10 51 0.001175 0.006946
788 REGULATION OF COAGULATION 14 88 0.001211 0.007134
789 LEUKOCYTE PROLIFERATION 14 88 0.001211 0.007134
790 REGULATION OF CATION CHANNEL ACTIVITY 14 88 0.001211 0.007134
791 REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 11 60 0.001216 0.007145
792 MATERNAL PROCESS INVOLVED IN FEMALE PREGNANCY 11 60 0.001216 0.007145
793 REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 16 108 0.001234 0.00724
794 POSITIVE REGULATION OF METANEPHROS DEVELOPMENT 5 14 0.001246 0.007267
795 SENSORY ORGAN MORPHOGENESIS 28 239 0.001241 0.007267
796 CELLULAR RESPONSE TO VITAMIN D 5 14 0.001246 0.007267
797 ANGIOGENESIS INVOLVED IN WOUND HEALING 5 14 0.001246 0.007267
798 POSITIVE REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION INVOLVED IN PHOSPHOLIPASE C ACTIVATING G PROTEIN COUPLED SIGNALING PATHWAY 5 14 0.001246 0.007267
799 REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 9 43 0.001262 0.007342
800 CEREBRAL CORTEX CELL MIGRATION 9 43 0.001262 0.007342
801 ANTERIOR POSTERIOR PATTERN SPECIFICATION 24 194 0.001278 0.007424
802 REGULATION OF CARBOHYDRATE METABOLIC PROCESS 22 172 0.001294 0.007505
803 DENDRITE DEVELOPMENT 13 79 0.001301 0.007531
804 REGULATION OF STRIATED MUSCLE CONTRACTION 13 79 0.001301 0.007531
805 IMMUNE RESPONSE REGULATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 35 323 0.001352 0.007812
806 RESPONSE TO HEAT 14 89 0.001355 0.007815
807 EPITHELIAL CELL PROLIFERATION 14 89 0.001355 0.007815
808 MYELOID LEUKOCYTE MIGRATION 15 99 0.001373 0.00785
809 REGULATION OF ADENYLATE CYCLASE ACTIVITY 12 70 0.001369 0.00785
810 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 15 99 0.001373 0.00785
811 MUSCLE ORGAN MORPHOGENESIS 12 70 0.001369 0.00785
812 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 15 99 0.001373 0.00785
813 INTERFERON GAMMA MEDIATED SIGNALING PATHWAY 12 70 0.001369 0.00785
814 LIPID PHOSPHORYLATION 15 99 0.001373 0.00785
815 POSITIVE REGULATION OF LYASE ACTIVITY 11 61 0.0014 0.007966
816 POSITIVE REGULATION OF CYCLASE ACTIVITY 11 61 0.0014 0.007966
817 REGULATION OF POTASSIUM ION TRANSMEMBRANE TRANSPORT 11 61 0.0014 0.007966
818 POSITIVE REGULATION OF STEM CELL PROLIFERATION 11 61 0.0014 0.007966
819 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 26 218 0.001407 0.007994
820 POSITIVE REGULATION OF ACUTE INFLAMMATORY RESPONSE 7 28 0.001461 0.008256
821 MUSCLE HYPERTROPHY 7 28 0.001461 0.008256
822 POSITIVE REGULATION OF CHEMOTAXIS 17 120 0.001462 0.008256
823 REGULATION OF DENDRITE DEVELOPMENT 17 120 0.001462 0.008256
824 POSITIVE REGULATION OF PHOSPHATASE ACTIVITY 7 28 0.001461 0.008256
825 CALCIUM MEDIATED SIGNALING 14 90 0.001513 0.008464
826 DECIDUALIZATION 6 21 0.001512 0.008464
827 NEGATIVE REGULATION OF ORGAN GROWTH 6 21 0.001512 0.008464
828 PLASMA LIPOPROTEIN PARTICLE CLEARANCE 6 21 0.001512 0.008464
829 POSITIVE T CELL SELECTION 6 21 0.001512 0.008464
830 POSITIVE REGULATION OF EXCITATORY POSTSYNAPTIC POTENTIAL 6 21 0.001512 0.008464
831 REGULATION OF CELL MATRIX ADHESION 14 90 0.001513 0.008464
832 REGULATION OF GLIOGENESIS 14 90 0.001513 0.008464
833 POSITIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 15 100 0.001523 0.008498
834 PEPTIDYL TYROSINE DEPHOSPHORYLATION 15 100 0.001523 0.008498
835 RETINA DEVELOPMENT IN CAMERA TYPE EYE 18 131 0.001535 0.008552
836 NEUROMUSCULAR JUNCTION DEVELOPMENT 8 36 0.001551 0.008621
837 CORTICAL CYTOSKELETON ORGANIZATION 8 36 0.001551 0.008621
838 SEX DIFFERENTIATION 30 266 0.001556 0.008639
839 POSITIVE REGULATION OF PHOSPHOLIPASE ACTIVITY 10 53 0.001598 0.008843
840 NEGATIVE REGULATION OF AUTOPHAGY 10 53 0.001598 0.008843
841 SKELETAL MUSCLE CELL DIFFERENTIATION 10 53 0.001598 0.008843
842 NEGATIVE REGULATION OF IMMUNE RESPONSE 17 121 0.001603 0.008858
843 GLYCOLIPID BIOSYNTHETIC PROCESS 11 62 0.001607 0.008869
844 REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION 15 101 0.001686 0.009297
845 CELLULAR RESPONSE TO OXYGEN LEVELS 19 143 0.001721 0.009477
846 REGULATION OF CYTOSKELETON ORGANIZATION 49 502 0.001728 0.009503
847 POTASSIUM ION TRANSPORT 20 154 0.001746 0.009581
848 RESPONSE TO STARVATION 20 154 0.001746 0.009581
849 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 17 122 0.001755 0.009619
850 REGULATION OF B CELL RECEPTOR SIGNALING PATHWAY 5 15 0.001773 0.009624
851 ENDOTHELIAL CELL DEVELOPMENT 9 45 0.00177 0.009624
852 REGULATION OF HEAT GENERATION 5 15 0.001773 0.009624
853 REGULATION OF N METHYL D ASPARTATE SELECTIVE GLUTAMATE RECEPTOR ACTIVITY 5 15 0.001773 0.009624
854 NEGATIVE REGULATION OF SMOOTH MUSCLE CONTRACTION 5 15 0.001773 0.009624
855 RESPONSE TO TUMOR NECROSIS FACTOR 27 233 0.001762 0.009624
856 POSITIVE REGULATION OF MONOCYTE CHEMOTAXIS 5 15 0.001773 0.009624
857 REGULATION OF SYSTEMIC ARTERIAL BLOOD PRESSURE MEDIATED BY A CHEMICAL SIGNAL 9 45 0.00177 0.009624
858 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 38 365 0.00179 0.009707
859 REGULATION OF EXTRACELLULAR MATRIX ORGANIZATION 7 29 0.001822 0.009832
860 CARBOHYDRATE DERIVATIVE METABOLIC PROCESS 90 1047 0.001819 0.009832
861 PIGMENT CELL DIFFERENTIATION 7 29 0.001822 0.009832
862 POSITIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 7 29 0.001822 0.009832
863 NEUROEPITHELIAL CELL DIFFERENTIATION 11 63 0.001837 0.009907
864 CELLULAR RESPONSE TO EXTRACELLULAR STIMULUS 23 188 0.001848 0.009952
865 ALPHA BETA T CELL ACTIVATION 10 54 0.001852 0.009952
866 POSITIVE REGULATION OF CALCIUM ION IMPORT 10 54 0.001852 0.009952
867 REGULATION OF JAK STAT CASCADE 19 144 0.001868 0.009992
868 REGULATION OF MUSCLE HYPERTROPHY 8 37 0.00187 0.009992
869 POSITIVE REGULATION OF TYROSINE PHOSPHORYLATION OF STAT3 PROTEIN 8 37 0.00187 0.009992
870 REGULATION OF RESPONSE TO CYTOKINE STIMULUS 19 144 0.001868 0.009992
871 REGULATION OF STAT CASCADE 19 144 0.001868 0.009992
NumGOOverlapSizeP ValueAdj. P Value
1 RECEPTOR BINDING 183 1476 2.164e-19 2.01e-16
2 CALCIUM ION BINDING 101 697 3.126e-15 1.452e-12
3 CYTOKINE BINDING 26 92 5.255e-11 1.585e-08
4 CYTOSKELETAL PROTEIN BINDING 101 819 6.824e-11 1.585e-08
5 ACTIN BINDING 58 393 1.416e-09 1.986e-07
6 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 80 629 1.71e-09 1.986e-07
7 ENZYME BINDING 172 1737 1.323e-09 1.986e-07
8 CELL ADHESION MOLECULE BINDING 36 186 1.508e-09 1.986e-07
9 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 49 315 4.683e-09 4.834e-07
10 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 50 328 6.511e-09 6.049e-07
11 KINASE BINDING 76 606 8.178e-09 6.907e-07
12 GROWTH FACTOR BINDING 27 123 1.022e-08 7.912e-07
13 PROTEIN COMPLEX BINDING 103 935 2.176e-08 1.555e-06
14 CORECEPTOR ACTIVITY 14 38 3.545e-08 2.352e-06
15 MOLECULAR FUNCTION REGULATOR 135 1353 6.265e-08 3.88e-06
16 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 37 226 9.411e-08 5.464e-06
17 INTEGRIN BINDING 23 105 1.296e-07 6.69e-06
18 CYTOKINE ACTIVITY 36 219 1.259e-07 6.69e-06
19 REGULATORY REGION NUCLEIC ACID BINDING 89 818 3.546e-07 1.734e-05
20 MACROMOLECULAR COMPLEX BINDING 135 1399 4.277e-07 1.987e-05
21 METALLOENDOPEPTIDASE ACTIVITY 23 113 5.253e-07 2.324e-05
22 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 43 303 5.625e-07 2.375e-05
23 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 35 228 1.001e-06 4.042e-05
24 CYTOKINE RECEPTOR BINDING 39 271 1.312e-06 5.078e-05
25 HEPARIN BINDING 27 157 1.885e-06 7.005e-05
26 GLYCOSAMINOGLYCAN BINDING 32 205 1.989e-06 7.063e-05
27 TRANSFORMING GROWTH FACTOR BETA BINDING 8 16 2.053e-06 7.063e-05
28 SIALYLTRANSFERASE ACTIVITY 9 21 2.326e-06 7.719e-05
29 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 116 1199 2.611e-06 8.364e-05
30 GLYCOPROTEIN BINDING 20 101 4.45e-06 0.0001378
31 GROWTH FACTOR RECEPTOR BINDING 23 129 5.73e-06 0.0001717
32 SIGNAL TRANSDUCER ACTIVITY 154 1731 7.482e-06 0.0002106
33 G PROTEIN COUPLED RECEPTOR BINDING 36 259 7.387e-06 0.0002106
34 SULFUR COMPOUND BINDING 33 234 1.288e-05 0.000352
35 CATION CHANNEL ACTIVITY 39 298 1.327e-05 0.0003523
36 PROTEIN DOMAIN SPECIFIC BINDING 67 624 1.55e-05 0.0003999
37 EXTRACELLULAR MATRIX STRUCTURAL CONSTITUENT 16 76 1.766e-05 0.0004434
38 ION CHANNEL BINDING 20 111 1.949e-05 0.0004765
39 METALLOPEPTIDASE ACTIVITY 28 188 2.083e-05 0.0004963
40 METAL ION TRANSMEMBRANE TRANSPORTER ACTIVITY 49 417 2.186e-05 0.0005077
41 PASSIVE TRANSMEMBRANE TRANSPORTER ACTIVITY 53 464 2.264e-05 0.000513
42 VOLTAGE GATED ION CHANNEL ACTIVITY 28 190 2.539e-05 0.0005615
43 PHOSPHORIC ESTER HYDROLASE ACTIVITY 44 368 3.722e-05 0.0008042
44 ACTIVATING TRANSCRIPTION FACTOR BINDING 13 57 4.402e-05 0.0009294
45 TUBULIN BINDING 35 273 5.545e-05 0.001145
46 PROTEIN HOMODIMERIZATION ACTIVITY 72 722 8.532e-05 0.001723
47 GATED CHANNEL ACTIVITY 39 325 9.31e-05 0.001809
48 CORE PROMOTER PROXIMAL REGION DNA BINDING 43 371 9.346e-05 0.001809
49 VIRUS RECEPTOR ACTIVITY 14 70 0.0001053 0.001956
50 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 14 70 0.0001053 0.001956
51 SMAD BINDING 14 72 0.0001446 0.002635
52 VOLTAGE GATED SODIUM CHANNEL ACTIVITY 7 20 0.0001494 0.002669
53 COLLAGEN BINDING 13 65 0.0001842 0.003168
54 RECEPTOR ACTIVITY 140 1649 0.0001818 0.003168
55 GABA RECEPTOR BINDING 6 15 0.0001936 0.003271
56 PROTEIN DIMERIZATION ACTIVITY 103 1149 0.0002001 0.00332
57 CHEMOKINE BINDING 7 21 0.0002119 0.003453
58 RECEPTOR SIGNALING PROTEIN ACTIVITY 24 172 0.0002202 0.003528
59 SEQUENCE SPECIFIC DNA BINDING 94 1037 0.0002596 0.004087
60 PROTEASE BINDING 17 104 0.0002742 0.004245
61 DOUBLE STRANDED DNA BINDING 73 764 0.0002811 0.004281
62 CYCLASE ACTIVITY 7 22 0.0002939 0.004403
63 SH3 DOMAIN BINDING 18 116 0.0003561 0.005252
64 IDENTICAL PROTEIN BINDING 106 1209 0.0003669 0.005326
65 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE ACTIVITY 6 17 0.0004291 0.006132
66 CYTOKINE RECEPTOR ACTIVITY 15 89 0.0004396 0.006187
67 GROWTH FACTOR ACTIVITY 22 160 0.0004859 0.006737
68 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II DISTAL ENHANCER SEQUENCE SPECIFIC BINDING 15 90 0.0004972 0.006792
69 WNT PROTEIN BINDING 8 31 0.000536 0.007216
70 PROTEIN KINASE ACTIVITY 62 640 0.0005557 0.007375
71 ACTIN FILAMENT BINDING 18 121 0.0005998 0.007848
72 TRANSMEMBRANE TRANSPORTER ACTIVITY 89 997 0.0006149 0.007934
73 KINASE ACTIVITY 77 842 0.0007145 0.009093
NumGOOverlapSizeP ValueAdj. P Value
1 INTRINSIC COMPONENT OF PLASMA MEMBRANE 203 1649 3.596e-21 2.1e-18
2 MEMBRANE REGION 154 1134 4.765e-20 1.391e-17
3 CELL PROJECTION 206 1786 3.497e-18 6.808e-16
4 NEURON PROJECTION 131 942 5.517e-18 8.055e-16
5 NEURON PART 160 1265 8.636e-18 1.009e-15
6 PROTEINACEOUS EXTRACELLULAR MATRIX 69 356 4.316e-17 4.201e-15
7 SYNAPSE 110 754 1.024e-16 8.54e-15
8 CELL JUNCTION 146 1151 2.218e-16 1.619e-14
9 CELL SURFACE 109 757 3.65e-16 2.368e-14
10 EXTRACELLULAR MATRIX 73 426 5.002e-15 2.921e-13
11 PLASMA MEMBRANE REGION 122 929 6.6e-15 3.504e-13
12 SOMATODENDRITIC COMPARTMENT 95 650 1.274e-14 6.198e-13
13 PLASMA MEMBRANE PROTEIN COMPLEX 80 510 3.719e-14 1.671e-12
14 MEMBRANE MICRODOMAIN 55 288 1.318e-13 5.496e-12
15 CELL LEADING EDGE 60 350 1.381e-12 5.378e-11
16 SIDE OF MEMBRANE 66 428 1.467e-11 5.354e-10
17 SYNAPSE PART 83 610 2.874e-11 9.875e-10
18 GOLGI APPARATUS 154 1445 5.969e-11 1.937e-09
19 CELL BODY 71 494 6.838e-11 2.102e-09
20 POSTSYNAPSE 59 378 1.095e-10 3.198e-09
21 EXTRACELLULAR SPACE 147 1376 1.453e-10 4.041e-09
22 EXTRACELLULAR MATRIX COMPONENT 30 125 1.56e-10 4.142e-09
23 DENDRITE 65 451 3.933e-10 9.986e-09
24 RECEPTOR COMPLEX 52 327 7.162e-10 1.743e-08
25 CELL PROJECTION PART 106 946 5.389e-09 1.259e-07
26 EXTERNAL SIDE OF PLASMA MEMBRANE 40 238 1.35e-08 3.032e-07
27 FILOPODIUM 23 94 1.426e-08 3.079e-07
28 CONTRACTILE FIBER 37 211 1.476e-08 3.079e-07
29 LEADING EDGE MEMBRANE 28 134 1.73e-08 3.484e-07
30 EXCITATORY SYNAPSE 35 197 2.555e-08 4.975e-07
31 SARCOLEMMA 26 125 6.128e-08 1.154e-06
32 CELL SUBSTRATE JUNCTION 54 398 9.541e-08 1.741e-06
33 PROTEIN COMPLEX INVOLVED IN CELL ADHESION 12 30 1.168e-07 2.068e-06
34 RUFFLE 29 156 1.445e-07 2.482e-06
35 CELL CELL JUNCTION 52 383 1.609e-07 2.685e-06
36 AXON 55 418 2.031e-07 3.295e-06
37 ENDOPLASMIC RETICULUM 154 1631 2.344e-07 3.699e-06
38 CELL CELL CONTACT ZONE 17 64 3.038e-07 4.549e-06
39 PLASMA MEMBRANE RAFT 20 86 3.025e-07 4.549e-06
40 INTERCALATED DISC 15 51 3.54e-07 5.168e-06
41 ACTIN BASED CELL PROJECTION 31 181 3.677e-07 5.238e-06
42 ACTIN CYTOSKELETON 56 444 6.367e-07 8.853e-06
43 SYNAPTIC MEMBRANE 38 261 1.339e-06 1.819e-05
44 ANCHORING JUNCTION 59 489 1.403e-06 1.862e-05
45 I BAND 23 121 1.845e-06 2.394e-05
46 CATION CHANNEL COMPLEX 28 167 2.058e-06 2.613e-05
47 T TUBULE 13 45 2.672e-06 3.32e-05
48 NEURON SPINE 22 121 6.548e-06 7.966e-05
49 GOLGI APPARATUS PART 90 893 7.495e-06 8.858e-05
50 MEMBRANE PROTEIN COMPLEX 100 1020 7.584e-06 8.858e-05
51 AXON PART 32 219 8.286e-06 9.488e-05
52 RUFFLE MEMBRANE 17 80 8.529e-06 9.579e-05
53 PRESYNAPSE 38 283 9.429e-06 0.0001039
54 LAMELLIPODIUM 27 172 1.102e-05 0.0001192
55 ENDOSOME 81 793 1.327e-05 0.0001409
56 PLASMA MEMBRANE RECEPTOR COMPLEX 27 175 1.522e-05 0.0001561
57 VACUOLE 111 1180 1.524e-05 0.0001561
58 BASEMENT MEMBRANE 18 93 1.834e-05 0.0001847
59 SITE OF POLARIZED GROWTH 24 149 2.155e-05 0.0002133
60 ENDOPLASMIC RETICULUM LUMEN 29 201 2.749e-05 0.0002676
61 CYTOPLASMIC VESICLE PART 64 601 3.08e-05 0.0002948
62 INTRACELLULAR VESICLE 115 1259 3.87e-05 0.0003645
63 COMPLEX OF COLLAGEN TRIMERS 8 23 5.244e-05 0.0004861
64 NEURON PROJECTION TERMINUS 21 129 5.881e-05 0.0005366
65 GOLGI MEMBRANE 71 703 6.437e-05 0.0005783
66 CELL PROJECTION MEMBRANE 37 298 6.852e-05 0.0006063
67 COSTAMERE 7 19 0.0001027 0.0008951
68 ACTIN FILAMENT 14 70 0.0001053 0.0009043
69 COLLAGEN TRIMER 16 88 0.0001152 0.0009754
70 VOLTAGE GATED SODIUM CHANNEL COMPLEX 6 14 0.0001228 0.00101
71 FIBRIL 6 14 0.0001228 0.00101
72 PRESYNAPTIC MEMBRANE 12 55 0.0001357 0.0011
73 PERIKARYON 18 108 0.0001424 0.001139
74 CYTOPLASMIC REGION 35 287 0.000152 0.001199
75 MAIN AXON 12 58 0.0002313 0.001801
76 CELL CORTEX 30 238 0.0002467 0.001895
77 BASAL PART OF CELL 11 51 0.0002849 0.002161
78 VESICLE MEMBRANE 53 512 0.0002916 0.002184
79 NEURON PROJECTION MEMBRANE 9 36 0.0003143 0.002323
80 PRESYNAPTIC ACTIVE ZONE 8 29 0.0003266 0.002384
81 PLATELET DENSE TUBULAR NETWORK 5 11 0.0003375 0.002434
82 APICAL PART OF CELL 40 361 0.0004106 0.002924
83 SODIUM CHANNEL COMPLEX 6 17 0.0004291 0.003019
84 POSTSYNAPTIC MEMBRANE 26 205 0.0005638 0.00392
85 ENDOPLASMIC RETICULUM PART 101 1163 0.000696 0.004782
86 MYELIN SHEATH 22 168 0.0009468 0.006429
87 LYTIC VACUOLE 52 526 0.0009594 0.00644
88 PERINUCLEAR REGION OF CYTOPLASM 61 642 0.0009932 0.006591
89 CYTOPLASMIC SIDE OF MEMBRANE 22 170 0.001109 0.007274
90 TRANS GOLGI NETWORK 24 193 0.001189 0.007718
91 TRANSPORTER COMPLEX 35 321 0.001214 0.007788
92 EXTRINSIC COMPONENT OF CYTOPLASMIC SIDE OF PLASMA MEMBRANE 15 98 0.001236 0.007846
93 CELL CORTEX PART 17 119 0.001332 0.008362
94 ENDOCYTIC VESICLE MEMBRANE 20 152 0.001489 0.009248
95 SECRETORY VESICLE 46 461 0.00152 0.009344
96 ACTOMYOSIN 11 62 0.001607 0.009775
97 CORTICAL CYTOSKELETON 13 81 0.001646 0.009913

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 PI3K_Akt_signaling_pathway_hsa04151 57 352 5.253e-11 2.732e-09
2 Focal_adhesion_hsa04510 39 199 2.147e-10 3.82e-09
3 Cytokine_cytokine_receptor_interaction_hsa04060 47 270 2.204e-10 3.82e-09
4 Cell_adhesion_molecules_.CAMs._hsa04514 32 145 3.907e-10 5.079e-09
5 ECM_receptor_interaction_hsa04512 22 82 4.637e-09 4.823e-08
6 MAPK_signaling_pathway_hsa04010 46 295 1.281e-08 1.11e-07
7 Regulation_of_actin_cytoskeleton_hsa04810 35 208 1.041e-07 7.734e-07
8 cGMP_PKG_signaling_pathway_hsa04022 28 163 1.252e-06 8.141e-06
9 Apelin_signaling_pathway_hsa04371 24 137 4.968e-06 2.87e-05
10 Rap1_signaling_pathway_hsa04015 29 206 4.36e-05 0.0002267
11 Hippo_signaling_pathway_hsa04390 23 154 0.0001056 0.0004992
12 Jak_STAT_signaling_pathway_hsa04630 23 162 0.0002281 0.0009886
13 Gap_junction_hsa04540 15 88 0.0003878 0.001551
14 Wnt_signaling_pathway_hsa04310 20 146 0.0009006 0.003345
15 Calcium_signaling_pathway_hsa04020 23 182 0.001198 0.004154
16 Ras_signaling_pathway_hsa04014 27 232 0.001655 0.005377
17 Phospholipase_D_signaling_pathway_hsa04072 19 146 0.002193 0.006655
18 TGF_beta_signaling_pathway_hsa04350 13 84 0.002304 0.006655
19 cAMP_signaling_pathway_hsa04024 23 198 0.003594 0.009836
20 HIF_1_signaling_pathway_hsa04066 14 100 0.004118 0.01071
21 NF_kappa_B_signaling_pathway_hsa04064 13 95 0.006774 0.01677
22 Hippo_signaling_pathway_multiple_species_hsa04392 6 29 0.008578 0.02028
23 Neuroactive_ligand_receptor_interaction_hsa04080 28 278 0.01029 0.02327
24 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 16 139 0.0148 0.03098
25 Adherens_junction_hsa04520 10 72 0.01489 0.03098
26 Sphingolipid_signaling_pathway_hsa04071 14 118 0.01706 0.03412
27 ErbB_signaling_pathway_hsa04012 11 85 0.01804 0.03475
28 TNF_signaling_pathway_hsa04668 13 108 0.01886 0.03503
29 FoxO_signaling_pathway_hsa04068 15 132 0.01989 0.03567
30 ABC_transporters_hsa02010 7 45 0.022 0.03814
31 Cellular_senescence_hsa04218 17 160 0.02509 0.04208
32 Ferroptosis_hsa04216 6 40 0.03853 0.0626
33 Apoptosis_hsa04210 14 138 0.05453 0.08593
34 Phagosome_hsa04145 15 152 0.05825 0.08908
35 Lysosome_hsa04142 11 123 0.1559 0.2316
36 Phosphatidylinositol_signaling_system_hsa04070 9 99 0.1745 0.2454
37 Hedgehog_signaling_pathway_hsa04340 5 47 0.1746 0.2454
38 Necroptosis_hsa04217 13 164 0.2397 0.328
39 Oocyte_meiosis_hsa04114 10 124 0.2597 0.3463
40 Tight_junction_hsa04530 13 170 0.2804 0.3645
41 Autophagy_animal_hsa04140 10 128 0.292 0.3703
42 VEGF_signaling_pathway_hsa04370 5 59 0.3176 0.3932
43 Apoptosis_multiple_species_hsa04215 3 33 0.3481 0.4087
44 AMPK_signaling_pathway_hsa04152 9 121 0.3582 0.4087
45 mTOR_signaling_pathway_hsa04150 11 151 0.3598 0.4087
46 Notch_signaling_pathway_hsa04330 4 48 0.3616 0.4087
47 Mitophagy_animal_hsa04137 5 65 0.3942 0.4361
48 Endocytosis_hsa04144 16 244 0.4791 0.5191
49 p53_signaling_pathway_hsa04115 4 68 0.6317 0.6704
50 Peroxisome_hsa04146 4 83 0.7787 0.8098
51 Cell_cycle_hsa04110 6 124 0.8044 0.8202

Quest ID: 7c31ca91a1bea06adf310efe7f4e2def