CR2Cancer

Summary
Symbol	BAZ1A
Name	bromodomain adjacent to zinc finger domain 1A
Aliases	hACF1; ACF1; WALp1; WCRF180; ATP-dependent chromatin remodeling protein; ATP-dependent chromatin-remodeling ......
Location	14q13.1-q13.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

[ TOP ]

Domain

PF00439 Bromodomain
PF02791 DDT domain
PF00628 PHD-finger
PF10537 ATP-utilising chromatin assembly and remodelling N-terminal
PF15612 WSTF
PF15613 Williams-Beuren syndrome DDT (WSD)

Function

Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase. Moves end-positioned nucleosomes to a predominantly central position. May have a role in nuclear receptor-mediated transcription repression.; FUNCTION: Component of the histone-fold protein complex CHRAC complex which faciliates nucleosome sliding by the ACF complex and enhances ACF-mediated chromatin assembly. The C-terminal regions of both CHRAC1 and POLE1 are required for these functions.

Classification

Class	Modification	Substrate	Product	PubMed
Histone chaperone	#	#	#	14759371

> Gene Ontology [ TOP ]
Biological Process	GO:0006260 DNA replication GO:0006261 DNA-dependent DNA replication GO:0006338 chromatin remodeling
Molecular Function	-
Cellular Component	GO:0008623 CHRAC GO:0016590 ACF complex GO:0031010 ISWI-type complex GO:0070603 SWI/SNF superfamily-type complex

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	-

Summary
Symbol	BAZ1A
Name	bromodomain adjacent to zinc finger domain 1A
Aliases	hACF1; ACF1; WALp1; WCRF180; ATP-dependent chromatin remodeling protein; ATP-dependent chromatin-remodeling ......
Location	14q13.1-q13.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM4541182	c.2959G>A	p.E987K	Substitution - Missense	Skin
COSM4880186	c.2885A>G	p.N962S	Substitution - Missense	Prostate
COSM1369654	c.1427delT	p.F476fs*3	Deletion - Frameshift	Large_intestine
COSM3495805	c.3520C>T	p.H1174Y	Substitution - Missense	Skin
COSM4927841	c.826A>G	p.R276G	Substitution - Missense	Liver
COSM5897874	c.59C>T	p.P20L	Substitution - Missense	Skin
COSM147764	c.4653G>A	p.A1551A	Substitution - coding silent	Stomach
COSM4577839	c.2599T>C	p.S867P	Substitution - Missense	Bone
COSM955454	c.4438C>T	p.R1480C	Substitution - Missense	Large_intestine
COSM5784800	c.3947G>C	p.R1316T	Substitution - Missense	Breast
COSM2195870	c.4016G>A	p.S1339N	Substitution - Missense	Upper_aerodigestive_tract
COSM955477	c.296C>T	p.S99L	Substitution - Missense	Large_intestine
COSM1369660	c.167T>C	p.V56A	Substitution - Missense	Large_intestine
COSM697916	c.1193C>A	p.P398H	Substitution - Missense	Lung
COSM955455	c.4033G>A	p.A1345T	Substitution - Missense	Endometrium
COSM1607641	c.2067G>T	p.L689L	Substitution - coding silent	Liver
COSM223686	c.4048G>A	p.E1350K	Substitution - Missense	Skin
COSM5606345	c.343C>T	p.R115*	Substitution - Nonsense	Skin
COSM3401297	c.344G>A	p.R115Q	Substitution - Missense	Central_nervous_system
COSM697921	c.3409G>C	p.D1137H	Substitution - Missense	Lung
COSM1184473	c.2819A>C	p.K940T	Substitution - Missense	Large_intestine
COSM274117	c.128G>A	p.R43Q	Substitution - Missense	Large_intestine
COSM1369652	c.2606C>T	p.S869F	Substitution - Missense	Large_intestine
COSM5382224	c.587C>T	p.P196L	Substitution - Missense	Skin
COSM955464	c.2467C>T	p.L823F	Substitution - Missense	Skin
COSM4493271	c.4122C>T	p.F1374F	Substitution - coding silent	Skin
COSM1323508	c.4320A>G	p.Q1440Q	Substitution - coding silent	Stomach
COSM3706248	c.553A>G	p.I185V	Substitution - Missense	Liver
COSM955473	c.869A>G	p.N290S	Substitution - Missense	Endometrium
COSM1369647	c.4054C>T	p.L1352F	Substitution - Missense	Large_intestine
COSM4791474	c.3319C>T	p.R1107C	Substitution - Missense	Liver
COSM5445334	c.1467_1469delAGA	p.E491delE	Deletion - In frame	Oesophagus
COSM1184474	c.1590G>A	p.W530*	Substitution - Nonsense	Large_intestine
COSM1707264	c.1768C>T	p.R590C	Substitution - Missense	Skin
COSM2195887	c.2627G>A	p.R876H	Substitution - Missense	Large_intestine
COSM3814729	c.1248G>A	p.V416V	Substitution - coding silent	Breast
COSM3700854	c.464G>T	p.S155I	Substitution - Missense	Liver
COSM697913	c.506C>G	p.S169*	Substitution - Nonsense	Lung
COSM3729594	c.590C>T	p.T197I	Substitution - Missense	Stomach
COSM4245462	c.420C>A	p.L140L	Substitution - coding silent	Large_intestine
COSM5637364	c.2720C>G	p.A907G	Substitution - Missense	Oesophagus
COSM4050620	c.3854G>A	p.R1285H	Substitution - Missense	Stomach
COSM4050625	c.1241C>A	p.T414K	Substitution - Missense	Stomach
COSM3495802	c.4508C>T	p.S1503L	Substitution - Missense	Stomach
COSM5802856	c.2242A>G	p.R748G	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1707261	c.3599G>A	p.R1200H	Substitution - Missense	Skin
COSM4050621	c.3446C>T	p.A1149V	Substitution - Missense	Stomach
COSM4995507	c.3856G>T	p.G1286C	Substitution - Missense	Upper_aerodigestive_tract
COSM3495803	c.4389C>T	p.V1463V	Substitution - coding silent	Skin
COSM1748819	c.1651G>C	p.E551Q	Substitution - Missense	Urinary_tract
COSM4803347	c.2734G>C	p.G912R	Substitution - Missense	Liver
COSM4928948	c.3831A>C	p.K1277N	Substitution - Missense	Liver
COSM955456	c.3753C>T	p.D1251D	Substitution - coding silent	Endometrium
COSM3814727	c.2194G>A	p.E732K	Substitution - Missense	Breast
COSM4451285	c.1143A>G	p.L381L	Substitution - coding silent	Skin
COSM5046900	c.2567C>T	p.S856F	Substitution - Missense	Oesophagus
COSM955467	c.2267T>G	p.F756C	Substitution - Missense	Endometrium
COSM1580560	c.2693G>C	p.C898S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM697920	c.3295C>G	p.P1099A	Substitution - Missense	Lung
COSM5500575	c.4387-9A>G	p.?	Unknown	Biliary_tract
COSM459180	c.2939G>C	p.R980T	Substitution - Missense	Cervix
COSM1184470	c.3356C>A	p.S1119Y	Substitution - Missense	Large_intestine
COSM5606345	c.343C>T	p.R115*	Substitution - Nonsense	Skin
COSM5735078	c.4072C>T	p.R1358C	Substitution - Missense	Pancreas
COSM5606345	c.343C>T	p.R115*	Substitution - Nonsense	Skin
COSM5547266	c.1137_1138delGA	p.K380fs*3	Deletion - Frameshift	Prostate
COSM4533349	c.1970G>A	p.R657Q	Substitution - Missense	Skin
COSM416706	c.4268G>A	p.R1423Q	Substitution - Missense	Urinary_tract
COSM1188795	c.2642A>G	p.Q881R	Substitution - Missense	Lung
COSM4591229	c.2116G>A	p.E706K	Substitution - Missense	Upper_aerodigestive_tract
COSM5382223	c.1925G>A	p.R642Q	Substitution - Missense	Skin
COSM4791474	c.3319C>T	p.R1107C	Substitution - Missense	Large_intestine
COSM3814731	c.141C>T	p.C47C	Substitution - coding silent	Breast
COSM5606345	c.343C>T	p.R115*	Substitution - Nonsense	Skin
COSM3744313	c.3543G>A	p.K1181K	Substitution - coding silent	Liver
COSM3744312	c.4267C>G	p.R1423G	Substitution - Missense	Liver
COSM1369649	c.3763G>T	p.E1255*	Substitution - Nonsense	Large_intestine
COSM955458	c.3695A>G	p.D1232G	Substitution - Missense	Endometrium
COSM955469	c.2002C>T	p.R668C	Substitution - Missense	Endometrium
COSM955477	c.296C>T	p.S99L	Substitution - Missense	Skin
COSM697922	c.4094A>G	p.N1365S	Substitution - Missense	Lung
COSM955454	c.4438C>T	p.R1480C	Substitution - Missense	Stomach
COSM4599434	c.1459G>A	p.E487K	Substitution - Missense	Upper_aerodigestive_tract
COSM3419783	c.2071G>C	p.E691Q	Substitution - Missense	Large_intestine
COSM3495804	c.4114C>T	p.P1372S	Substitution - Missense	Skin
COSM4805205	c.3262G>C	p.E1088Q	Substitution - Missense	Liver
COSM5382220	c.3252C>T	p.L1084L	Substitution - coding silent	Skin
COSM469924	c.1248G>T	p.V416V	Substitution - coding silent	Kidney
COSM73809	c.212A>T	p.E71V	Substitution - Missense	Ovary
COSM3987627	c.3000T>C	p.V1000V	Substitution - coding silent	Kidney
COSM5630001	c.2356G>A	p.E786K	Substitution - Missense	Oesophagus
COSM1579291	c.1591C>G	p.P531A	Substitution - Missense	Fallopian_tube
COSM5890797	c.3666G>A	p.M1222I	Substitution - Missense	Skin
COSM955476	c.475G>T	p.E159*	Substitution - Nonsense	Endometrium
COSM955477	c.296C>T	p.S99L	Substitution - Missense	Endometrium
COSM1369659	c.219delA	p.A74fs*12	Deletion - Frameshift	Large_intestine
COSM1184474	c.1590G>A	p.W530*	Substitution - Nonsense	Prostate
COSM3706248	c.553A>G	p.I185V	Substitution - Missense	Liver
COSM1580558	c.4652C>T	p.A1551V	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1677940	c.3371C>A	p.A1124D	Substitution - Missense	Large_intestine
COSM400342	c.3352G>A	p.E1118K	Substitution - Missense	Lung
COSM5606345	c.343C>T	p.R115*	Substitution - Nonsense	Skin
COSM3764493	c.521G>C	p.C174S	Substitution - Missense	Central_nervous_system
COSM955475	c.598G>T	p.E200*	Substitution - Nonsense	Endometrium
COSM697918	c.1399G>A	p.E467K	Substitution - Missense	Lung
COSM1677940	c.3371C>A	p.A1124D	Substitution - Missense	Large_intestine
COSM4791474	c.3319C>T	p.R1107C	Substitution - Missense	Liver
COSM1188796	c.58C>G	p.P20A	Substitution - Missense	Lung
COSM2195898	c.1808C>T	p.T603I	Substitution - Missense	Upper_aerodigestive_tract
COSM5045601	c.3587G>A	p.R1196Q	Substitution - Missense	Oesophagus
COSM5382222	c.2411C>T	p.P804L	Substitution - Missense	Skin
COSM4665205	c.3044A>G	p.Y1015C	Substitution - Missense	Large_intestine
COSM955452	c.4509G>A	p.S1503S	Substitution - coding silent	Large_intestine
COSM1162779	c.136C>G	p.L46V	Substitution - Missense	Pancreas
COSM1369656	c.1261C>T	p.P421S	Substitution - Missense	Large_intestine
COSM1607640	c.2361A>G	p.K787K	Substitution - coding silent	Liver
COSM223687	c.710G>A	p.G237E	Substitution - Missense	Skin
COSM5684538	c.224G>T	p.R75I	Substitution - Missense	Soft_tissue
COSM4445417	c.1225-3C>T	p.?	Unknown	Skin
COSM433031	c.4169C>T	p.S1390F	Substitution - Missense	Breast
COSM5475770	c.2140A>G	p.S714G	Substitution - Missense	Large_intestine
COSM955463	c.2494C>A	p.L832I	Substitution - Missense	Endometrium
COSM4776701	c.3736G>C	p.E1246Q	Substitution - Missense	Breast
COSM697919	c.3252C>G	p.L1084L	Substitution - coding silent	Lung
COSM3814730	c.1014G>T	p.K338N	Substitution - Missense	Breast
COSM5637363	c.2762C>A	p.T921N	Substitution - Missense	Oesophagus
COSM697923	c.4124C>T	p.P1375L	Substitution - Missense	Lung
COSM5909358	c.3620G>A	p.R1207K	Substitution - Missense	Skin
COSM4777020	c.1915G>C	p.D639H	Substitution - Missense	Breast
COSM4665204	c.3271A>G	p.I1091V	Substitution - Missense	Large_intestine
COSM433033	c.2848G>C	p.D950H	Substitution - Missense	Breast
COSM3706247	c.1129-9A>C	p.?	Unknown	Liver
COSM955459	c.2947C>A	p.L983I	Substitution - Missense	Endometrium
COSM4479656	c.2347C>T	p.Q783*	Substitution - Nonsense	Skin
COSM5690203	c.4081A>T	p.R1361W	Substitution - Missense	Soft_tissue
COSM955474	c.743C>T	p.T248M	Substitution - Missense	Stomach
COSM1607642	c.165T>C	p.A55A	Substitution - coding silent	Liver
COSM5053928	c.1924C>T	p.R642*	Substitution - Nonsense	Stomach
COSM4622945	c.196G>A	p.E66K	Substitution - Missense	Large_intestine
COSM4430024	c.3828G>A	p.G1276G	Substitution - coding silent	Oesophagus
COSM397478	c.734C>G	p.S245C	Substitution - Missense	Lung
COSM1748820	c.1467A>G	p.E489E	Substitution - coding silent	Urinary_tract
COSM6001378	c.3449G>A	p.R1150H	Substitution - Missense	Prostate
COSM955453	c.4438C>A	p.R1480S	Substitution - Missense	Endometrium
COSM955454	c.4438C>T	p.R1480C	Substitution - Missense	Skin
COSM5882495	c.1016A>C	p.K339T	Substitution - Missense	Skin
COSM4921854	c.4085A>G	p.K1362R	Substitution - Missense	Liver
COSM955472	c.929A>G	p.K310R	Substitution - Missense	Endometrium
COSM127422	c.171G>T	p.T57T	Substitution - coding silent	Upper_aerodigestive_tract
COSM955468	c.2102T>C	p.I701T	Substitution - Missense	Endometrium
COSM3793674	c.3658G>C	p.D1220H	Substitution - Missense	Urinary_tract
COSM4917858	c.4325T>C	p.V1442A	Substitution - Missense	Liver
COSM3886027	c.1781C>T	p.P594L	Substitution - Missense	Skin
COSM4665203	c.4200A>G	p.Q1400Q	Substitution - coding silent	Large_intestine
COSM4136247	c.4009C>T	p.R1337C	Substitution - Missense	Pancreas
COSM279119	c.749A>C	p.K250T	Substitution - Missense	Large_intestine
COSM4405953	c.2990C>T	p.A997V	Substitution - Missense	Skin
COSM433032	c.3244A>G	p.M1082V	Substitution - Missense	Breast
COSM955462	c.2758G>A	p.E920K	Substitution - Missense	Endometrium
COSM1369646	c.4226delG	p.R1409fs*11	Deletion - Frameshift	Large_intestine
COSM5589790	c.3853C>T	p.R1285C	Substitution - Missense	Skin
COSM213023	c.2489C>T	p.S830F	Substitution - Missense	Breast
COSM955451	c.4609G>A	p.V1537I	Substitution - Missense	Endometrium
COSM3753948	c.1335A>G	p.Q445Q	Substitution - coding silent	Breast
COSM433035	c.2362G>A	p.E788K	Substitution - Missense	Breast
COSM25442	c.491G>A	p.S164N	Substitution - Missense	Skin
COSM4665207	c.2481G>T	p.E827D	Substitution - Missense	Large_intestine
COSM2195893	c.1967A>G	p.H656R	Substitution - Missense	Large_intestine
COSM5625760	c.1544C>T	p.P515L	Substitution - Missense	Oesophagus
COSM697924	c.4291G>A	p.G1431R	Substitution - Missense	Lung
COSM1369648	c.3764A>T	p.E1255V	Substitution - Missense	Large_intestine
COSM1300578	c.4330G>C	p.E1444Q	Substitution - Missense	Urinary_tract
COSM5689398	c.189delG	p.Y64fs*22	Deletion - Frameshift	Soft_tissue
COSM1707264	c.1768C>T	p.R590C	Substitution - Missense	Skin
COSM4973477	c.4571C>T	p.A1524V	Substitution - Missense	Oesophagus
COSM1607642	c.165T>C	p.A55A	Substitution - coding silent	Liver
COSM955478	c.161G>A	p.C54Y	Substitution - Missense	Endometrium
COSM2195928	c.102C>T	p.F34F	Substitution - coding silent	Large_intestine
COSM5462380	c.4283G>A	p.R1428Q	Substitution - Missense	Large_intestine
COSM3495808	c.1345C>T	p.P449S	Substitution - Missense	Skin
COSM697915	c.851A>G	p.H284R	Substitution - Missense	Lung
COSM4800598	c.3297A>C	p.P1099P	Substitution - coding silent	Liver
COSM4508563	c.780C>T	p.F260F	Substitution - coding silent	Skin
COSM4983413	c.1986A>T	p.E662D	Substitution - Missense	Oesophagus
COSM1184471	c.4532G>A	p.R1511H	Substitution - Missense	Large_intestine
COSM955454	c.4438C>T	p.R1480C	Substitution - Missense	Large_intestine
COSM1600364	c.1558_1565delCTGTCTGC	p.L520fs*23	Deletion - Frameshift	Central_nervous_system
COSM3690061	c.4608C>T	p.H1536H	Substitution - coding silent	Stomach
COSM3706248	c.553A>G	p.I185V	Substitution - Missense	Liver
COSM4600362	c.3437T>A	p.I1146K	Substitution - Missense	Upper_aerodigestive_tract
COSM39870	c.1341G>A	p.E447E	Substitution - coding silent	Central_nervous_system
COSM1369651	c.2830delT	p.S944fs*34	Deletion - Frameshift	Large_intestine
COSM3814726	c.3035G>C	p.S1012T	Substitution - Missense	Breast
COSM5500576	c.1652A>C	p.E551A	Substitution - Missense	Biliary_tract
COSM2195863	c.4578delT	p.H1527fs*>30	Deletion - Frameshift	Large_intestine
COSM3495810	c.953A>G	p.K318R	Substitution - Missense	Skin
COSM5980569	c.546_547insA	p.D183fs*4	Insertion - Frameshift	Upper_aerodigestive_tract
COSM5554593	c.4080C>T	p.G1360G	Substitution - coding silent	Prostate
COSM3495802	c.4508C>T	p.S1503L	Substitution - Missense	Skin
COSM1707264	c.1768C>T	p.R590C	Substitution - Missense	Skin
COSM4050627	c.714C>T	p.V238V	Substitution - coding silent	Stomach
COSM955461	c.2841T>A	p.P947P	Substitution - coding silent	Endometrium
COSM32529	c.4268delG	p.R1423fs*21	Deletion - Frameshift	Breast
COSM955474	c.743C>T	p.T248M	Substitution - Missense	Endometrium
COSM3814732	c.36G>A	p.Q12Q	Substitution - coding silent	Breast
COSM4665208	c.2345A>G	p.H782R	Substitution - Missense	Large_intestine
COSM3690061	c.4608C>T	p.H1536H	Substitution - coding silent	Large_intestine
COSM4050622	c.3277C>T	p.R1093W	Substitution - Missense	Stomach
COSM1748818	c.3083T>C	p.I1028T	Substitution - Missense	Urinary_tract
COSM5647278	c.372C>T	p.V124V	Substitution - coding silent	Oesophagus
COSM88162	c.113+2T>G	p.?	Unknown	Central_nervous_system
COSM4050623	c.2546A>G	p.Q849R	Substitution - Missense	Stomach
COSM4805205	c.3262G>C	p.E1088Q	Substitution - Missense	Liver
COSM955464	c.2467C>T	p.L823F	Substitution - Missense	Endometrium
COSM1323508	c.4320A>G	p.Q1440Q	Substitution - coding silent	Ovary
COSM3495806	c.1863T>G	p.C621W	Substitution - Missense	Skin
COSM3720949	c.282C>T	p.S94S	Substitution - coding silent	Upper_aerodigestive_tract
COSM955457	c.3751G>A	p.D1251N	Substitution - Missense	Endometrium
COSM341707	c.4561A>G	p.R1521G	Substitution - Missense	Lung
COSM1369661	c.123delT	p.F41fs*16	Deletion - Frameshift	Large_intestine
COSM5423480	c.1572A>G	p.A524A	Substitution - coding silent	Prostate
COSM469923	c.2798T>C	p.L933P	Substitution - Missense	Kidney
COSM5647277	c.3721G>A	p.E1241K	Substitution - Missense	Oesophagus
COSM4791474	c.3319C>T	p.R1107C	Substitution - Missense	Large_intestine
COSM4803347	c.2734G>C	p.G912R	Substitution - Missense	Liver
COSM955466	c.2350C>T	p.R784*	Substitution - Nonsense	Endometrium
COSM955454	c.4438C>T	p.R1480C	Substitution - Missense	Endometrium
COSM5630006	c.2358delG	p.E788fs*3	Deletion - Frameshift	Oesophagus
COSM1707263	c.3274G>A	p.E1092K	Substitution - Missense	Skin
COSM1369655	c.1318_1319insG	p.E440fs*4	Insertion - Frameshift	Large_intestine
COSM1607641	c.2067G>T	p.L689L	Substitution - coding silent	Liver
COSM955465	c.2406C>A	p.I802I	Substitution - coding silent	Endometrium
COSM4912906	c.1624T>C	p.L542L	Substitution - coding silent	Liver
COSM3753948	c.1335A>G	p.Q445Q	Substitution - coding silent	Large_intestine
COSM3495809	c.1231C>T	p.P411S	Substitution - Missense	Skin
COSM3955999	c.572A>G	p.K191R	Substitution - Missense	Lung
COSM4516403	c.1893_1894GG>AA	p.D632N	Substitution - Missense	Skin
COSM5987891	c.4207G>A	p.E1403K	Substitution - Missense	Salivary_gland
COSM1748819	c.1651G>C	p.E551Q	Substitution - Missense	Urinary_tract
COSM955460	c.2941G>T	p.D981Y	Substitution - Missense	Endometrium
COSM1607642	c.165T>C	p.A55A	Substitution - coding silent	Liver
COSM5429866	c.3274G>C	p.E1092Q	Substitution - Missense	Oesophagus
COSM5795490	c.4616C>A	p.P1539H	Substitution - Missense	Breast
COSM1707264	c.1768C>T	p.R590C	Substitution - Missense	Skin
COSM25441	c.4241C>T	p.P1414L	Substitution - Missense	Lung
COSM4577840	c.2514G>A	p.L838L	Substitution - coding silent	Bone
COSM697926	c.4292G>A	p.G1431E	Substitution - Missense	Lung
COSM4665206	c.2568C>A	p.S856S	Substitution - coding silent	Large_intestine
COSM2195863	c.4578delT	p.H1527fs*>30	Deletion - Frameshift	Large_intestine
COSM2195898	c.1808C>T	p.T603I	Substitution - Missense	Large_intestine
COSM4540640	c.2873G>A	p.G958E	Substitution - Missense	Skin
COSM1748820	c.1467A>G	p.E489E	Substitution - coding silent	Urinary_tract
COSM4800598	c.3297A>C	p.P1099P	Substitution - coding silent	Liver
COSM955452	c.4509G>A	p.S1503S	Substitution - coding silent	Endometrium
COSM3814728	c.1384G>C	p.V462L	Substitution - Missense	Breast
COSM1629279	c.2426G>A	p.R809H	Substitution - Missense	Liver
COSM4050621	c.3446C>T	p.A1149V	Substitution - Missense	Large_intestine
COSM1748818	c.3083T>C	p.I1028T	Substitution - Missense	Urinary_tract
COSM433034	c.2765T>A	p.L922*	Substitution - Nonsense	Breast
COSM5382221	c.2560C>T	p.Q854*	Substitution - Nonsense	Skin
COSM3983237	c.3265C>G	p.Q1089E	Substitution - Missense	Ovary
COSM1184472	c.1725A>C	p.K575N	Substitution - Missense	Large_intestine
COSM3495811	c.744G>A	p.T248T	Substitution - coding silent	Stomach
COSM955471	c.1145G>A	p.R382H	Substitution - Missense	Endometrium
COSM5002357	c.4098T>A	p.N1366K	Substitution - Missense	Pancreas
COSM4050624	c.2387C>T	p.A796V	Substitution - Missense	Stomach
COSM4050624	c.2387C>T	p.A796V	Substitution - Missense	Skin
COSM3793673	c.4365G>C	p.L1455F	Substitution - Missense	Urinary_tract
COSM4050626	c.1139A>G	p.K380R	Substitution - Missense	Stomach
COSM697914	c.624A>G	p.K208K	Substitution - coding silent	Lung
COSM1580559	c.3661A>G	p.S1221G	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5803859	c.685A>G	p.K229E	Substitution - Missense	Liver
COSM4887787	c.4457G>T	p.C1486F	Substitution - Missense	Upper_aerodigestive_tract
COSM697917	c.1327G>C	p.D443H	Substitution - Missense	Lung
COSM119883	c.1325T>C	p.F442S	Substitution - Missense	Ovary
COSM3495807	c.1860C>T	p.L620L	Substitution - coding silent	Skin
COSM2195917	c.777C>A	p.F259L	Substitution - Missense	Large_intestine
COSM25406	c.244C>T	p.P82S	Substitution - Missense	Lung
COSM955470	c.1471G>T	p.E491*	Substitution - Nonsense	Endometrium
COSM3495811	c.744G>A	p.T248T	Substitution - coding silent	Skin
COSM4572497	c.766T>A	p.F256I	Substitution - Missense	Skin
COSM1607640	c.2361A>G	p.K787K	Substitution - coding silent	Liver
COSM1707262	c.3412C>T	p.R1138C	Substitution - Missense	Skin

> Text Mining based Variations [ TOP ]
There is no record for BAZ1A.

Summary
Symbol	BAZ1A
Name	bromodomain adjacent to zinc finger domain 1A
Aliases	hACF1; ACF1; WALp1; WCRF180; ATP-dependent chromatin remodeling protein; ATP-dependent chromatin-remodeling ......
Location	14q13.1-q13.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

[ TOP ]

Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant
Q9NRL2	702	S	Phosphoserine	-	No	None detected
Q9NRL2	731	T	Phosphothreonine	-	No	None detected
Q9NRL2	960	S	Phosphoserine	-	No	None detected
Q9NRL2	961	S	Phosphoserine	-	Yes	p.S961Y (cancer: LUAD)
Q9NRL2	1281	S	Phosphoserine	-	No	None detected
Q9NRL2	1320	S	Phosphoserine	-	No	None detected
Q9NRL2	1339	S	Phosphoserine	-	No	None detected
Q9NRL2	1353	S	Phosphoserine	-	No	None detected
Q9NRL2	1363	S	Phosphoserine	-	No	None detected
Q9NRL2	1371	S	Phosphoserine	-	No	None detected
Q9NRL2	1402	S	Phosphoserine	-	No	None detected
Q9NRL2	1413	S	Phosphoserine	-	No	None detected
Q9NRL2	1417	S	Phosphoserine	-	No	None detected
Q9NRL2	1547	T	Phosphothreonine	-	No	None detected

Summary
Symbol	BAZ1A
Name	bromodomain adjacent to zinc finger domain 1A
Aliases	hACF1; ACF1; WALp1; WCRF180; ATP-dependent chromatin remodeling protein; ATP-dependent chromatin-remodeling ......
Location	14q13.1-q13.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	5.681	6.047	0.402	0.0226	NS
BRCA	Breast invasive carcinoma	112	1100	5.58	6.059	0.487	2.42e-15	NS
CESC	Cervical and endocervical cancers	3	306	4.499	6.323	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	5.563	5.717	0.098	0.358	NS
ESCA	Esophageal carcinoma	11	185	6.048	6.963	0.917	3.14e-05	Over
GBM	Glioblastoma multiforme	5	166	2.386	4.812	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	6.164	6.322	0.35	0.00161	NS
KIRC	Kidney renal clear cell carcinoma	72	534	3.888	5.237	1.2	2.51e-49	Over
KIRP	Kidney renal papillary cell carcinoma	32	291	3.53	4.895	1.138	8.62e-19	Over
LAML	Acute Myeloid Leukemia	0	173	NA	8.198	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	4.718	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	3.97	3.972	-0.072	0.562	NS
LUAD	Lung adenocarcinoma	59	517	5.73	6.185	0.412	2.9e-05	NS
LUSC	Lung squamous cell carcinoma	51	501	5.768	6.274	0.408	3.56e-06	NS
OV	Ovarian serous cystadenocarcinoma	0	307	NA	5.547	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	5.639	5.603	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	4.263	3.413	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	5.028	5.438	0.376	4.25e-06	NS
READ	Rectum adenocarcinoma	10	167	5.318	5.605	0.164	0.493	NS
SARC	Sarcoma	2	263	3.465	5.169	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	5.828	5.282	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	5.913	6.55	0.653	1.22e-07	Over
TGCT	Testicular Germ Cell Tumors	0	156	NA	4.389	NA	NA	NA
THCA	Thyroid carcinoma	59	509	4.283	5.035	0.579	9.84e-13	NS
THYM	Thymoma	2	120	5.827	5.459	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	4.625	5.566	0.787	3.16e-10	Over

> Cancer Cell Line Encyclopedia (CCLE)

[ TOP ]

Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	10
Autonomic ganglia	CHP212	10.6
Autonomic ganglia	IMR32	10.5
Autonomic ganglia	KELLY	10.8
Autonomic ganglia	KPNRTBM1	10.3
Autonomic ganglia	KPNSI9S	9.6
Autonomic ganglia	KPNYN	10.6
Autonomic ganglia	MHHNB11	8.3
Autonomic ganglia	NB1	10.5
Autonomic ganglia	NH6	10
Autonomic ganglia	SHSY5Y	9.2
Autonomic ganglia	SIMA	10.6
Autonomic ganglia	SKNAS	10.1
Autonomic ganglia	SKNBE2	10.9
Autonomic ganglia	SKNDZ	10.9
Autonomic ganglia	SKNFI	9
Autonomic ganglia	SKNSH	9.6
Biliary tract	HUCCT1	8.3
Biliary tract	HUH28	8.1
Biliary tract	SNU1079	9.6
Biliary tract	SNU1196	9.9
Biliary tract	SNU245	9.4
Biliary tract	SNU308	9.9
Biliary tract	SNU478	9.9
Bone	143B	10.1
Bone	A673	9.7
Bone	CADOES1	9.2
Bone	CAL78	8
Bone	G292CLONEA141B1	9.6
Bone	HOS	10.2
Bone	HS706T	8.7
Bone	HS737T	8.3
Bone	HS819T	8.6
Bone	HS821T	8.8
Bone	HS822T	7.9
Bone	HS863T	9.1
Bone	HS870T	8.8
Bone	HS888T	9.3
Bone	MG63	8.9
Bone	MHHES1	10
Bone	OUMS27	9
Bone	RDES	9.9
Bone	SJSA1	9.4
Bone	SKES1	10.7
Bone	SKNMC	10.6
Bone	SW1353	9.2
Bone	T173	8.1
Bone	TC71	10.1
Bone	U2OS	8.6
Breast	AU565	10.4
Breast	BT20	9.5
Breast	BT474	11.1
Breast	BT483	10.3
Breast	BT549	9.6
Breast	CAL120	9.4
Breast	CAL148	10.4
Breast	CAL51	9.3
Breast	CAL851	9.1
Breast	CAMA1	9.6
Breast	DU4475	7.6
Breast	EFM192A	9.5
Breast	EFM19	10.3
Breast	EVSAT	9.1
Breast	HCC1143	9.5
Breast	HCC1187	10.1
Breast	HCC1395	9.9
Breast	HCC1419	10.3
Breast	HCC1428	10
Breast	HCC1500	10.4
Breast	HCC1569	8.9
Breast	HCC1599	10
Breast	HCC1806	8.9
Breast	HCC1937	9.7
Breast	HCC1954	10.4
Breast	HCC202	10
Breast	HCC2157	10.7
Breast	HCC2218	10
Breast	HCC38	9.8
Breast	HCC70	10.1
Breast	HDQP1	9.2
Breast	HMC18	9.3
Breast	HS274T	9.2
Breast	HS281T	9.4
Breast	HS343T	9.3
Breast	HS578T	8.3
Breast	HS606T	8.7
Breast	HS739T	8.6
Breast	HS742T	8.6
Breast	JIMT1	8.9
Breast	KPL1	10.8
Breast	MCF7	9.8
Breast	MDAMB134VI	9.2
Breast	MDAMB157	9.2
Breast	MDAMB175VII	9.4
Breast	MDAMB231	8.8
Breast	MDAMB361	9.5
Breast	MDAMB415	8.7
Breast	MDAMB436	9.1
Breast	MDAMB453	10.1
Breast	MDAMB468	9.4
Breast	SKBR3	10.3
Breast	T47D	9.5
Breast	UACC812	9.8
Breast	UACC893	11.3
Breast	YMB1	9.6
Breast	ZR751	9.8
Breast	ZR7530	9.5
Central nervous system	1321N1	9.8
Central nervous system	42MGBA	9.8
Central nervous system	8MGBA	9.1
Central nervous system	A172	8.7
Central nervous system	AM38	9.6
Central nervous system	BECKER	9.4
Central nervous system	CAS1	9.4
Central nervous system	CCFSTTG1	9
Central nervous system	D283MED	10
Central nervous system	D341MED	9.6
Central nervous system	DAOY	10.7
Central nervous system	DBTRG05MG	7.8
Central nervous system	DKMG	8.6
Central nervous system	GAMG	9.1
Central nervous system	GB1	10.1
Central nervous system	GI1	9.3
Central nervous system	GMS10	10
Central nervous system	GOS3	7.5
Central nervous system	H4	9.4
Central nervous system	HS683	9
Central nervous system	KALS1	9.6
Central nervous system	KG1C	8.3
Central nervous system	KNS42	9.3
Central nervous system	KNS60	8.7
Central nervous system	KNS81	8
Central nervous system	KS1	9
Central nervous system	LN18	9
Central nervous system	LN229	8.7
Central nervous system	M059K	9.5
Central nervous system	MOGGCCM	8.7
Central nervous system	MOGGUVW	10.1
Central nervous system	NMCG1	8.7
Central nervous system	ONS76	10
Central nervous system	SF126	9.6
Central nervous system	SF295	8.8
Central nervous system	SNB19	8.9
Central nervous system	SNU1105	8.3
Central nervous system	SNU201	7.8
Central nervous system	SNU466	7.1
Central nervous system	SNU489	8.3
Central nervous system	SNU626	9.2
Central nervous system	SNU738	8.3
Central nervous system	SW1088	8.8
Central nervous system	SW1783	9.4
Central nervous system	T98G	8.5
Central nervous system	TM31	9.4
Central nervous system	U118MG	9.1
Central nervous system	U138MG	8.8
Central nervous system	U251MG	8.9
Central nervous system	U87MG	7.8
Central nervous system	YH13	9.1
Central nervous system	YKG1	9.4
Endometrium	AN3CA	9.7
Endometrium	COLO684	9.8
Endometrium	EFE184	10.3
Endometrium	EN	9.5
Endometrium	ESS1	9.4
Endometrium	HEC108	9.8
Endometrium	HEC151	10.2
Endometrium	HEC1A	9.7
Endometrium	HEC1B	9
Endometrium	HEC251	9.9
Endometrium	HEC265	9.6
Endometrium	HEC50B	10
Endometrium	HEC59	9
Endometrium	HEC6	10.3
Endometrium	ISHIKAWAHERAKLIO02ER	9.5
Endometrium	JHUEM1	8.6
Endometrium	JHUEM2	10.4
Endometrium	JHUEM3	9.4
Endometrium	KLE	8
Endometrium	MFE280	8.1
Endometrium	MFE296	9.1
Endometrium	MFE319	10
Endometrium	RL952	9.5
Endometrium	SNGM	10.1
Endometrium	SNU1077	9.7
Endometrium	SNU685	9.2
Endometrium	TEN	10.4
Haematopoietic and lymphoid	697	10.6
Haematopoietic and lymphoid	A3KAW	10.6
Haematopoietic and lymphoid	A4FUK	10.8
Haematopoietic and lymphoid	ALLSIL	10.4
Haematopoietic and lymphoid	AML193	10.6
Haematopoietic and lymphoid	AMO1	8.8
Haematopoietic and lymphoid	BCP1	10.2
Haematopoietic and lymphoid	BDCM	9.9
Haematopoietic and lymphoid	BL41	10.7
Haematopoietic and lymphoid	BL70	10.4
Haematopoietic and lymphoid	BV173	10.1
Haematopoietic and lymphoid	CA46	9.3
Haematopoietic and lymphoid	CI1	10.7
Haematopoietic and lymphoid	CMK115	10.2
Haematopoietic and lymphoid	CMK86	10.5
Haematopoietic and lymphoid	CMK	9.8
Haematopoietic and lymphoid	CMLT1	10.2
Haematopoietic and lymphoid	COLO775	9.3
Haematopoietic and lymphoid	DAUDI	10.6
Haematopoietic and lymphoid	DB	10.4
Haematopoietic and lymphoid	DEL	10.4
Haematopoietic and lymphoid	DND41	9.7
Haematopoietic and lymphoid	DOHH2	11
Haematopoietic and lymphoid	EB1	10.3
Haematopoietic and lymphoid	EB2	10.2
Haematopoietic and lymphoid	EHEB	10.6
Haematopoietic and lymphoid	EJM	8.4
Haematopoietic and lymphoid	EM2	9.6
Haematopoietic and lymphoid	EOL1	10.5
Haematopoietic and lymphoid	F36P	9.6
Haematopoietic and lymphoid	GA10	10.4
Haematopoietic and lymphoid	GDM1	9.7
Haematopoietic and lymphoid	GRANTA519	10.1
Haematopoietic and lymphoid	HDLM2	9.4
Haematopoietic and lymphoid	HDMYZ	8.8
Haematopoietic and lymphoid	HEL9217	10
Haematopoietic and lymphoid	HEL	10.3
Haematopoietic and lymphoid	HH	10.4
Haematopoietic and lymphoid	HL60	10.8
Haematopoietic and lymphoid	HPBALL	9.7
Haematopoietic and lymphoid	HS604T	8.6
Haematopoietic and lymphoid	HS611T	10.2
Haematopoietic and lymphoid	HS616T	8.8
Haematopoietic and lymphoid	HS751T	9.5
Haematopoietic and lymphoid	HT	10.6
Haematopoietic and lymphoid	HTK	9.9
Haematopoietic and lymphoid	HUNS1	10.2
Haematopoietic and lymphoid	HUT102	9.8
Haematopoietic and lymphoid	HUT78	8.6
Haematopoietic and lymphoid	JEKO1	9.7
Haematopoietic and lymphoid	JK1	10.5
Haematopoietic and lymphoid	JM1	10.3
Haematopoietic and lymphoid	JURKAT	10.5
Haematopoietic and lymphoid	JURLMK1	10.2
Haematopoietic and lymphoid	JVM2	10.7
Haematopoietic and lymphoid	JVM3	9.9
Haematopoietic and lymphoid	K562	8.8
Haematopoietic and lymphoid	KARPAS299	9.9
Haematopoietic and lymphoid	KARPAS422	11.7
Haematopoietic and lymphoid	KARPAS620	10.6
Haematopoietic and lymphoid	KASUMI1	11
Haematopoietic and lymphoid	KASUMI2	10.6
Haematopoietic and lymphoid	KASUMI6	10.2
Haematopoietic and lymphoid	KCL22	10.1
Haematopoietic and lymphoid	KE37	10.8
Haematopoietic and lymphoid	KE97	9.7
Haematopoietic and lymphoid	KG1	10.1
Haematopoietic and lymphoid	KHM1B	9.8
Haematopoietic and lymphoid	KIJK	9.9
Haematopoietic and lymphoid	KMH2	10.2
Haematopoietic and lymphoid	KMM1	8.5
Haematopoietic and lymphoid	KMS11	9
Haematopoietic and lymphoid	KMS12BM	8.7
Haematopoietic and lymphoid	KMS18	9.6
Haematopoietic and lymphoid	KMS20	9.8
Haematopoietic and lymphoid	KMS21BM	8.8
Haematopoietic and lymphoid	KMS26	8.3
Haematopoietic and lymphoid	KMS27	9.7
Haematopoietic and lymphoid	KMS28BM	9.5
Haematopoietic and lymphoid	KMS34	9.1
Haematopoietic and lymphoid	KO52	10.3
Haematopoietic and lymphoid	KOPN8	9.4
Haematopoietic and lymphoid	KU812	10.8
Haematopoietic and lymphoid	KYO1	9.1
Haematopoietic and lymphoid	L1236	10.3
Haematopoietic and lymphoid	L363	10
Haematopoietic and lymphoid	L428	10.8
Haematopoietic and lymphoid	L540	9.8
Haematopoietic and lymphoid	LAMA84	10.5
Haematopoietic and lymphoid	LOUCY	9.9
Haematopoietic and lymphoid	LP1	8.7
Haematopoietic and lymphoid	M07E	11
Haematopoietic and lymphoid	MC116	10.1
Haematopoietic and lymphoid	ME1	9.2
Haematopoietic and lymphoid	MEC1	10.3
Haematopoietic and lymphoid	MEC2	11
Haematopoietic and lymphoid	MEG01	10.9
Haematopoietic and lymphoid	MHHCALL2	10.5
Haematopoietic and lymphoid	MHHCALL3	10.4
Haematopoietic and lymphoid	MHHCALL4	10.8
Haematopoietic and lymphoid	MINO	10.5
Haematopoietic and lymphoid	MJ	9.9
Haematopoietic and lymphoid	MM1S	8.6
Haematopoietic and lymphoid	MOLM13	10.7
Haematopoietic and lymphoid	MOLM16	10.6
Haematopoietic and lymphoid	MOLM6	9.7
Haematopoietic and lymphoid	MOLP2	8.1
Haematopoietic and lymphoid	MOLP8	9.7
Haematopoietic and lymphoid	MOLT13	10.6
Haematopoietic and lymphoid	MOLT16	10.7
Haematopoietic and lymphoid	MOLT4	10.6
Haematopoietic and lymphoid	MONOMAC1	11.2
Haematopoietic and lymphoid	MONOMAC6	11.3
Haematopoietic and lymphoid	MOTN1	9.7
Haematopoietic and lymphoid	MUTZ5	10.7
Haematopoietic and lymphoid	MV411	11
Haematopoietic and lymphoid	NALM19	9.9
Haematopoietic and lymphoid	NALM1	11
Haematopoietic and lymphoid	NALM6	10.8
Haematopoietic and lymphoid	NAMALWA	9.9
Haematopoietic and lymphoid	NB4	10.5
Haematopoietic and lymphoid	NCIH929	9.1
Haematopoietic and lymphoid	NCO2	10.6
Haematopoietic and lymphoid	NOMO1	10.5
Haematopoietic and lymphoid	NUDHL1	9.6
Haematopoietic and lymphoid	NUDUL1	11.2
Haematopoietic and lymphoid	OCIAML2	11.7
Haematopoietic and lymphoid	OCIAML3	10.2
Haematopoietic and lymphoid	OCIAML5	10.9
Haematopoietic and lymphoid	OCILY10	11.2
Haematopoietic and lymphoid	OCILY19	10.3
Haematopoietic and lymphoid	OCILY3	10.6
Haematopoietic and lymphoid	OCIM1	9.8
Haematopoietic and lymphoid	OPM2	9.2
Haematopoietic and lymphoid	P12ICHIKAWA	10.3
Haematopoietic and lymphoid	P31FUJ	9.8
Haematopoietic and lymphoid	P3HR1	10.4
Haematopoietic and lymphoid	PCM6	9.5
Haematopoietic and lymphoid	PEER	9.8
Haematopoietic and lymphoid	PF382	10.4
Haematopoietic and lymphoid	PFEIFFER	10.3
Haematopoietic and lymphoid	PL21	10.7
Haematopoietic and lymphoid	RAJI	10.3
Haematopoietic and lymphoid	RCHACV	10.8
Haematopoietic and lymphoid	REC1	10.5
Haematopoietic and lymphoid	REH	10.4
Haematopoietic and lymphoid	RI1	9.8
Haematopoietic and lymphoid	RL	10.7
Haematopoietic and lymphoid	RPMI8226	9.4
Haematopoietic and lymphoid	RPMI8402	10.2
Haematopoietic and lymphoid	RS411	10.3
Haematopoietic and lymphoid	SEM	10.4
Haematopoietic and lymphoid	SET2	10.6
Haematopoietic and lymphoid	SIGM5	11.6
Haematopoietic and lymphoid	SKM1	10.1
Haematopoietic and lymphoid	SKMM2	9.7
Haematopoietic and lymphoid	SR786	9.4
Haematopoietic and lymphoid	ST486	10.2
Haematopoietic and lymphoid	SUDHL10	9.7
Haematopoietic and lymphoid	SUDHL1	9.9
Haematopoietic and lymphoid	SUDHL4	9.7
Haematopoietic and lymphoid	SUDHL5	10.9
Haematopoietic and lymphoid	SUDHL6	10.7
Haematopoietic and lymphoid	SUDHL8	9.7
Haematopoietic and lymphoid	SUPB15	10.6
Haematopoietic and lymphoid	SUPHD1	9.7
Haematopoietic and lymphoid	SUPM2	9.7
Haematopoietic and lymphoid	SUPT11	8.8
Haematopoietic and lymphoid	SUPT1	10.5
Haematopoietic and lymphoid	TALL1	10.4
Haematopoietic and lymphoid	TF1	9.9
Haematopoietic and lymphoid	THP1	11.3
Haematopoietic and lymphoid	TO175T	8.5
Haematopoietic and lymphoid	TOLEDO	10.1
Haematopoietic and lymphoid	U266B1	7.5
Haematopoietic and lymphoid	U937	9.3
Haematopoietic and lymphoid	UT7	9.8
Haematopoietic and lymphoid	WSUDLCL2	9.9
Kidney	769P	9.2
Kidney	786O	8.9
Kidney	A498	8.6
Kidney	A704	8.2
Kidney	ACHN	9.9
Kidney	BFTC909	8.7
Kidney	CAKI1	8.3
Kidney	CAKI2	8.2
Kidney	CAL54	9.5
Kidney	KMRC1	9.5
Kidney	KMRC20	8.4
Kidney	KMRC2	8.9
Kidney	KMRC3	9.7
Kidney	OSRC2	9.2
Kidney	RCC10RGB	8.6
Kidney	SNU1272	8.4
Kidney	SNU349	8
Kidney	TUHR10TKB	8.5
Kidney	TUHR14TKB	8.4
Kidney	TUHR4TKB	8.2
Kidney	VMRCRCW	7.7
Kidney	VMRCRCZ	8.5
Large intestine	C2BBE1	9.1
Large intestine	CCK81	9.4
Large intestine	CL11	10.1
Large intestine	CL14	8.4
Large intestine	CL34	9.1
Large intestine	CL40	9.2
Large intestine	COLO205	9.3
Large intestine	COLO320	9.8
Large intestine	COLO678	9.2
Large intestine	CW2	6.5
Large intestine	DLD1	9.8
Large intestine	GP2D	9.7
Large intestine	HCC56	9.8
Large intestine	HCT116	9.8
Large intestine	HCT15	9.8
Large intestine	HS675T	9
Large intestine	HS698T	9.2
Large intestine	HT115	9.6
Large intestine	HT29	8.7
Large intestine	HT55	9.6
Large intestine	KM12	9.5
Large intestine	LOVO	9.7
Large intestine	LS1034	9.4
Large intestine	LS123	9.9
Large intestine	LS180	9.5
Large intestine	LS411N	9.7
Large intestine	LS513	9.9
Large intestine	MDST8	9.2
Large intestine	NCIH508	9.6
Large intestine	NCIH716	10.3
Large intestine	NCIH747	9.6
Large intestine	OUMS23	8.9
Large intestine	RCM1	9.3
Large intestine	RKO	10
Large intestine	SKCO1	10.6
Large intestine	SNU1040	9.3
Large intestine	SNU1197	9.6
Large intestine	SNU175	9
Large intestine	SNU283	9.5
Large intestine	SNU407	9.2
Large intestine	SNU503	10
Large intestine	SNU61	10.1
Large intestine	SNU81	9.8
Large intestine	SNUC1	9.6
Large intestine	SNUC2A	9.3
Large intestine	SNUC4	9.6
Large intestine	SNUC5	9.4
Large intestine	SW1116	9.4
Large intestine	SW1417	9.3
Large intestine	SW1463	9.9
Large intestine	SW403	9.6
Large intestine	SW480	8.8
Large intestine	SW48	10.1
Large intestine	SW620	9.7
Large intestine	SW837	9.6
Large intestine	SW948	9.6
Large intestine	T84	10.4
Liver	ALEXANDERCELLS	9.1
Liver	C3A	8.1
Liver	HEP3B217	10.8
Liver	HEPG2	9.4
Liver	HLE	9
Liver	HLF	9.2
Liver	HUH1	9.8
Liver	HUH6	8.3
Liver	HUH7	9.1
Liver	JHH1	8.5
Liver	JHH2	10.2
Liver	JHH4	9.4
Liver	JHH5	9.8
Liver	JHH6	9.9
Liver	JHH7	9.9
Liver	LI7	9.2
Liver	PLCPRF5	8.3
Liver	SKHEP1	9.9
Liver	SNU182	9.3
Liver	SNU387	8.3
Liver	SNU398	9.6
Liver	SNU423	9.3
Liver	SNU449	9.8
Liver	SNU475	10.1
Liver	SNU761	10
Liver	SNU878	8.3
Liver	SNU886	9.2
Lung	A549	9.7
Lung	ABC1	9.7
Lung	BEN	9.1
Lung	CAL12T	9.5
Lung	CALU1	8.8
Lung	CALU3	9.7
Lung	CALU6	9.5
Lung	CHAGOK1	8.9
Lung	COLO668	9.6
Lung	COLO699	8.6
Lung	CORL105	9.3
Lung	CORL23	10.6
Lung	CORL24	10.4
Lung	CORL279	10.2
Lung	CORL311	9.4
Lung	CORL47	9.4
Lung	CORL51	9.8
Lung	CORL88	10.2
Lung	CORL95	9
Lung	CPCN	10.2
Lung	DMS114	9.6
Lung	DMS153	9.4
Lung	DMS273	10.1
Lung	DMS454	8.4
Lung	DMS53	8.6
Lung	DMS79	11.4
Lung	DV90	9.6
Lung	EBC1	10.4
Lung	EPLC272H	9.6
Lung	HARA	10.6
Lung	HCC1171	9.8
Lung	HCC1195	12.7
Lung	HCC15	10.3
Lung	HCC2279	9.1
Lung	HCC2935	10.9
Lung	HCC33	10.9
Lung	HCC366	9.7
Lung	HCC4006	11.2
Lung	HCC44	10.7
Lung	HCC78	10.3
Lung	HCC827	11
Lung	HCC95	9.3
Lung	HLC1	8.8
Lung	HLFA	9.3
Lung	HS229T	9.5
Lung	HS618T	9.5
Lung	IALM	10.7
Lung	KNS62	9.5
Lung	LC1F	10.5
Lung	LC1SQSF	10.6
Lung	LCLC103H	9.3
Lung	LCLC97TM1	10.2
Lung	LK2	10.2
Lung	LOUNH91	7.9
Lung	LU65	9.7
Lung	LU99	9.2
Lung	LUDLU1	10
Lung	LXF289	9.6
Lung	MORCPR	9
Lung	NCIH1048	10.7
Lung	NCIH1092	10.1
Lung	NCIH1105	10.3
Lung	NCIH1155	9.8
Lung	NCIH1184	10.7
Lung	NCIH1299	9.4
Lung	NCIH1339	9.7
Lung	NCIH1341	9.4
Lung	NCIH1355	8.8
Lung	NCIH1373	9.3
Lung	NCIH1385	6.9
Lung	NCIH1395	9
Lung	NCIH1435	9.9
Lung	NCIH1436	9.8
Lung	NCIH1437	9.7
Lung	NCIH146	9.2
Lung	NCIH1563	8.3
Lung	NCIH1568	9.5
Lung	NCIH1573	7.9
Lung	NCIH1581	9.5
Lung	NCIH1618	9.5
Lung	NCIH1623	8.5
Lung	NCIH1648	10.6
Lung	NCIH1650	9
Lung	NCIH1651	10.3
Lung	NCIH1666	10
Lung	NCIH1693	9.3
Lung	NCIH1694	10.1
Lung	NCIH1703	9.3
Lung	NCIH1734	10.2
Lung	NCIH1755	9.3
Lung	NCIH1781	12.9
Lung	NCIH1792	10.3
Lung	NCIH1793	9.7
Lung	NCIH1836	10
Lung	NCIH1838	10
Lung	NCIH1869	10
Lung	NCIH1876	10.1
Lung	NCIH1915	9.8
Lung	NCIH1930	9.9
Lung	NCIH1944	9.3
Lung	NCIH1963	10.2
Lung	NCIH196	9.9
Lung	NCIH1975	9.8
Lung	NCIH2009	10.2
Lung	NCIH2023	9.3
Lung	NCIH2029	10.8
Lung	NCIH2030	9.1
Lung	NCIH2066	10.2
Lung	NCIH2081	10
Lung	NCIH2085	9.2
Lung	NCIH2087	10.5
Lung	NCIH209	9.3
Lung	NCIH2106	10.7
Lung	NCIH2110	10.4
Lung	NCIH211	11.1
Lung	NCIH2122	9.5
Lung	NCIH2126	8.8
Lung	NCIH2141	10.7
Lung	NCIH2170	10.8
Lung	NCIH2171	10.6
Lung	NCIH2172	9.9
Lung	NCIH2196	9.2
Lung	NCIH2227	9.7
Lung	NCIH2228	9.3
Lung	NCIH226	9.5
Lung	NCIH2286	9.8
Lung	NCIH2291	10
Lung	NCIH2342	11
Lung	NCIH2347	10
Lung	NCIH23	9.7
Lung	NCIH2405	9.4
Lung	NCIH2444	9.6
Lung	NCIH292	9.7
Lung	NCIH322	10.3
Lung	NCIH3255	10.8
Lung	NCIH358	10.6
Lung	NCIH441	9.6
Lung	NCIH446	10.9
Lung	NCIH460	10.6
Lung	NCIH510	10.1
Lung	NCIH520	9.3
Lung	NCIH522	10
Lung	NCIH524	10.9
Lung	NCIH526	10
Lung	NCIH596	10.1
Lung	NCIH647	9.6
Lung	NCIH650	9.8
Lung	NCIH661	11.4
Lung	NCIH69	10.7
Lung	NCIH727	9.1
Lung	NCIH810	10.5
Lung	NCIH82	10.1
Lung	NCIH838	10.3
Lung	NCIH841	9.2
Lung	NCIH854	9
Lung	NCIH889	9.4
Lung	PC14	8.3
Lung	RERFLCAD1	10.3
Lung	RERFLCAD2	8.2
Lung	RERFLCAI	9.8
Lung	RERFLCKJ	8.6
Lung	RERFLCMS	9.4
Lung	RERFLCSQ1	9.4
Lung	SBC5	8.7
Lung	SCLC21H	10.5
Lung	SHP77	10.4
Lung	SKLU1	9.4
Lung	SKMES1	8.4
Lung	SQ1	9.8
Lung	SW1271	8.9
Lung	SW1573	8.9
Lung	SW900	9
Lung	VMRCLCD	10.3
Lung	VMRCLCP	10.6
Oesophagus	COLO680N	9.2
Oesophagus	ECGI10	10.6
Oesophagus	KYSE140	10.9
Oesophagus	KYSE150	9.9
Oesophagus	KYSE180	11
Oesophagus	KYSE270	8.9
Oesophagus	KYSE30	8.8
Oesophagus	KYSE410	10.1
Oesophagus	KYSE450	9.5
Oesophagus	KYSE510	9.6
Oesophagus	KYSE520	8.7
Oesophagus	KYSE70	9
Oesophagus	OE19	9.2
Oesophagus	OE33	10.8
Oesophagus	TE10	11
Oesophagus	TE11	10.5
Oesophagus	TE14	10.2
Oesophagus	TE15	9.9
Oesophagus	TE1	9.9
Oesophagus	TE4	12
Oesophagus	TE5	10.4
Oesophagus	TE6	10.5
Oesophagus	TE8	10
Oesophagus	TE9	10.1
Oesophagus	TT	11.3
Ovary	59M	9.2
Ovary	A2780	9.1
Ovary	CAOV3	8
Ovary	CAOV4	8.4
Ovary	COLO704	10.2
Ovary	COV318	8.6
Ovary	COV362	8.1
Ovary	COV434	10.3
Ovary	COV504	7.8
Ovary	COV644	9.3
Ovary	EFO21	9.1
Ovary	EFO27	8.9
Ovary	ES2	9.9
Ovary	FUOV1	8.6
Ovary	HEYA8	10.1
Ovary	HS571T	8.2
Ovary	IGROV1	9.7
Ovary	JHOC5	10
Ovary	JHOM1	9.7
Ovary	JHOM2B	10.1
Ovary	JHOS2	9.5
Ovary	JHOS4	9.8
Ovary	KURAMOCHI	9.8
Ovary	MCAS	9.3
Ovary	NIHOVCAR3	9.7
Ovary	OAW28	8.1
Ovary	OAW42	9
Ovary	OC314	10.2
Ovary	OC316	10.1
Ovary	ONCODG1	9.6
Ovary	OV56	9
Ovary	OV7	9.3
Ovary	OV90	9.2
Ovary	OVCAR4	9.1
Ovary	OVCAR8	10.4
Ovary	OVISE	8.8
Ovary	OVK18	8.4
Ovary	OVKATE	9.6
Ovary	OVMANA	9.8
Ovary	OVSAHO	8.3
Ovary	OVTOKO	9.4
Ovary	RMGI	8.5
Ovary	RMUGS	8.6
Ovary	SKOV3	8.9
Ovary	SNU119	9.3
Ovary	SNU840	9.9
Ovary	SNU8	10.5
Ovary	TOV112D	8.9
Ovary	TOV21G	9.2
Ovary	TYKNU	9.5
Pancreas	ASPC1	9.3
Pancreas	BXPC3	9.6
Pancreas	CAPAN1	9.6
Pancreas	CAPAN2	9.5
Pancreas	CFPAC1	9.9
Pancreas	DANG	10.1
Pancreas	HPAC	9.5
Pancreas	HPAFII	10.5
Pancreas	HS766T	8.9
Pancreas	HUPT3	10.4
Pancreas	HUPT4	9.8
Pancreas	KCIMOH1	9.2
Pancreas	KLM1	9.2
Pancreas	KP2	8.8
Pancreas	KP3	9.2
Pancreas	KP4	9.7
Pancreas	L33	9.2
Pancreas	MIAPACA2	10.4
Pancreas	PANC0203	10.1
Pancreas	PANC0213	10.1
Pancreas	PANC0327	10.2
Pancreas	PANC0403	9.8
Pancreas	PANC0504	9.8
Pancreas	PANC0813	11.3
Pancreas	PANC1005	8.8
Pancreas	PANC1	9.3
Pancreas	PATU8902	8.8
Pancreas	PATU8988S	9.2
Pancreas	PATU8988T	9.4
Pancreas	PK1	9.7
Pancreas	PK45H	10
Pancreas	PK59	9.5
Pancreas	PL45	8.8
Pancreas	PSN1	10.5
Pancreas	QGP1	8
Pancreas	SNU213	10.1
Pancreas	SNU324	10.1
Pancreas	SNU410	9.1
Pancreas	SU8686	9.2
Pancreas	SUIT2	9.6
Pancreas	SW1990	9.6
Pancreas	T3M4	9.7
Pancreas	TCCPAN2	9.3
Pancreas	YAPC	10
Pleura	ACCMESO1	8.5
Pleura	DM3	8.9
Pleura	ISTMES1	10.2
Pleura	ISTMES2	9.8
Pleura	JL1	9.7
Pleura	MPP89	9.5
Pleura	MSTO211H	10
Pleura	NCIH2052	9.1
Pleura	NCIH2452	9.2
Pleura	NCIH28	8.8
Prostate	22RV1	10.4
Prostate	DU145	11.2
Prostate	LNCAPCLONEFGC	9.7
Prostate	MDAPCA2B	9.5
Prostate	NCIH660	9.6
Prostate	PC3	9.5
Prostate	VCAP	8.8
Salivary gland	A253	10.1
Salivary gland	YD15	9.9
Skin	A101D	9
Skin	A2058	9.7
Skin	A375	9.3
Skin	C32	9.3
Skin	CHL1	9.4
Skin	CJM	10.6
Skin	COLO679	9
Skin	COLO741	8.1
Skin	COLO783	10.4
Skin	COLO792	7.1
Skin	COLO800	8.9
Skin	COLO818	9.3
Skin	COLO829	9.1
Skin	COLO849	9.8
Skin	G361	9.2
Skin	GRM	10.2
Skin	HMCB	9.9
Skin	HS294T	8.1
Skin	HS600T	8.6
Skin	HS688AT	8.5
Skin	HS695T	7.7
Skin	HS839T	8.8
Skin	HS852T	9.5
Skin	HS895T	9.1
Skin	HS934T	8.7
Skin	HS936T	8.4
Skin	HS939T	9.6
Skin	HS940T	8.6
Skin	HS944T	8.6
Skin	HT144	9.4
Skin	IGR1	9.2
Skin	IGR37	7.9
Skin	IGR39	9.2
Skin	IPC298	9
Skin	K029AX	8.5
Skin	LOXIMVI	10
Skin	MALME3M	8.8
Skin	MDAMB435S	9.6
Skin	MELHO	9.3
Skin	MELJUSO	9.1
Skin	MEWO	9.5
Skin	RPMI7951	9.3
Skin	RVH421	8.7
Skin	SH4	9.2
Skin	SKMEL1	8.4
Skin	SKMEL24	8.7
Skin	SKMEL28	8.4
Skin	SKMEL2	9.1
Skin	SKMEL30	9.3
Skin	SKMEL31	8.4
Skin	SKMEL3	8.4
Skin	SKMEL5	8.7
Skin	UACC257	8.9
Skin	UACC62	9.9
Skin	WM115	9.5
Skin	WM1799	9.3
Skin	WM2664	9.1
Skin	WM793	9.8
Skin	WM88	9.2
Skin	WM983B	9.6
Small intestine	HUTU80	9.9
Soft tissue	A204	9
Soft tissue	G401	8.2
Soft tissue	G402	9.9
Soft tissue	GCT	9.2
Soft tissue	HS729	9.1
Soft tissue	HT1080	9.3
Soft tissue	KYM1	10
Soft tissue	MESSA	9.2
Soft tissue	RD	9.8
Soft tissue	RH30	9.2
Soft tissue	RH41	10.2
Soft tissue	RKN	10
Soft tissue	S117	9.9
Soft tissue	SJRH30	9.7
Soft tissue	SKLMS1	9.4
Soft tissue	SKUT1	9.8
Soft tissue	TE125T	8.7
Soft tissue	TE159T	8
Soft tissue	TE441T	9.1
Soft tissue	TE617T	9
Stomach	2313287	9.1
Stomach	AGS	10.1
Stomach	AZ521	10.3
Stomach	ECC10	9.8
Stomach	ECC12	10.1
Stomach	FU97	6.8
Stomach	GCIY	9.2
Stomach	GSS	8.8
Stomach	GSU	11.3
Stomach	HGC27	10.2
Stomach	HS746T	9.7
Stomach	HUG1N	9.1
Stomach	IM95	9.7
Stomach	KATOIII	9.6
Stomach	KE39	9.2
Stomach	LMSU	10.1
Stomach	MKN1	9
Stomach	MKN45	9.9
Stomach	MKN74	9.5
Stomach	MKN7	9.7
Stomach	NCCSTCK140	9.6
Stomach	NCIN87	8.7
Stomach	NUGC2	8.6
Stomach	NUGC3	9.5
Stomach	NUGC4	9.5
Stomach	OCUM1	10.1
Stomach	RERFGC1B	9
Stomach	SH10TC	8.7
Stomach	SNU16	10.3
Stomach	SNU1	9.9
Stomach	SNU216	10.2
Stomach	SNU520	9.4
Stomach	SNU5	9.5
Stomach	SNU601	9.9
Stomach	SNU620	9.9
Stomach	SNU668	10
Stomach	SNU719	9.1
Stomach	TGBC11TKB	9.7
Thyroid	8305C	9.1
Thyroid	8505C	9.8
Thyroid	BCPAP	8
Thyroid	BHT101	10.2
Thyroid	CAL62	10
Thyroid	CGTHW1	9.5
Thyroid	FTC133	9.7
Thyroid	FTC238	9.9
Thyroid	ML1	10.2
Thyroid	SW579	9.3
Thyroid	TT2609C02	10.3
Thyroid	TT	7.8
Upper aerodigestive tract	BHY	10.2
Upper aerodigestive tract	BICR16	7.5
Upper aerodigestive tract	BICR18	9.9
Upper aerodigestive tract	BICR22	10.1
Upper aerodigestive tract	BICR31	10.5
Upper aerodigestive tract	BICR56	10.3
Upper aerodigestive tract	BICR6	10.4
Upper aerodigestive tract	CAL27	9.9
Upper aerodigestive tract	CAL33	10.3
Upper aerodigestive tract	DETROIT562	10.2
Upper aerodigestive tract	FADU	10.6
Upper aerodigestive tract	HS840T	9.4
Upper aerodigestive tract	HSC2	9.5
Upper aerodigestive tract	HSC3	10.3
Upper aerodigestive tract	HSC4	9.7
Upper aerodigestive tract	PECAPJ15	10.2
Upper aerodigestive tract	PECAPJ34CLONEC12	10.2
Upper aerodigestive tract	PECAPJ41CLONED2	9.8
Upper aerodigestive tract	PECAPJ49	9.2
Upper aerodigestive tract	SCC15	9.7
Upper aerodigestive tract	SCC25	10.6
Upper aerodigestive tract	SCC4	9.8
Upper aerodigestive tract	SCC9	9.8
Upper aerodigestive tract	SNU1076	9.9
Upper aerodigestive tract	SNU1214	8.9
Upper aerodigestive tract	SNU46	9.4
Upper aerodigestive tract	SNU899	9.9
Upper aerodigestive tract	YD10B	9.6
Upper aerodigestive tract	YD38	10.2
Upper aerodigestive tract	YD8	9.5
Urinary tract	5637	9.6
Urinary tract	639V	10
Urinary tract	647V	9.8
Urinary tract	BC3C	10.1
Urinary tract	BFTC905	10
Urinary tract	CAL29	9.8
Urinary tract	HS172T	9.4
Urinary tract	HT1197	9.6
Urinary tract	HT1376	9.1
Urinary tract	J82	9.3
Urinary tract	JMSU1	9.8
Urinary tract	KMBC2	9.5
Urinary tract	KU1919	9.2
Urinary tract	RT11284	9.7
Urinary tract	RT112	9.3
Urinary tract	RT4	10
Urinary tract	SCABER	10
Urinary tract	SW1710	9.1
Urinary tract	SW780	9.8
Urinary tract	T24	9.3
Urinary tract	TCCSUP	9.5
Urinary tract	UMUC1	9.1
Urinary tract	UMUC3	9.9
Urinary tract	VMCUB1	10.7

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	16.7
Adrenal gland	6.9
Appendix	31.1
Bone marrow	47.5
Breast	14.6
Cerebral cortex	5.1
Cervix, uterine	12.1
Colon	12.5
Duodenum	10.5
Endometrium	12.6
Epididymis	8.8
Esophagus	14.2
Fallopian tube	10.2
Gallbladder	21.5
Heart muscle	2.3
Kidney	4.4
Liver	6.1
Lung	18.6
Lymph node	29.5
Ovary	6.9
Pancreas	1.4
Parathyroid gland	15.6
Placenta	18.1
Prostate	12.2
Rectum	14.6
Salivary gland	2.4
Seminal vesicle	8.2
Skeletal muscle	1.2
Skin	25.6
Small intestine	13.9
Smooth muscle	13
Spleen	28.1
Stomach	12.2
Testis	55.8
Thyroid gland	9.8
Tonsil	19.9
Urinary bladder	17

> Text Mining based Expression

[ TOP ]

PMID	Expression	Cancer	Evidence
11550278	overexpression (copy number gain)	Esophageal Squamous Cell Carcinoma	Five known genes (BAZ1A, SRP54, NFKBIA, MBIP, and HNF3A) and two uncharacterized ESTs (GenBank Accession numbers AA991861 and AA167732) within the amplicon showed amplification and consequent overexpression.

Summary
Symbol	BAZ1A
Name	bromodomain adjacent to zinc finger domain 1A
Aliases	hACF1; ACF1; WALp1; WCRF180; ATP-dependent chromatin remodeling protein; ATP-dependent chromatin-remodeling ......
Location	14q13.1-q13.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

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Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.349	5.56e-13	31.9	51.7	16.3	Neutral
BRCA	Breast invasive carcinoma	1075	0.417	1.79e-46	22	57.8	20.2	Neutral
CESC	Cervical and endocervical cancers	292	0.388	6.31e-12	11.6	72.9	15.4	Neutral
COAD	Colon adenocarcinoma	449	0.411	1.1e-19	31.8	59.7	8.5	Neutral
ESCA	Esophageal carcinoma	183	0.601	2.49e-19	25.7	43.7	30.6	Neutral
GBM	Glioblastoma multiforme	147	0.536	2.66e-12	35.4	59.9	4.8	Loss
HNSC	Head and Neck squamous cell carcinoma	514	0.465	7.15e-29	12.3	57.4	30.4	Neutral
KIRC	Kidney renal clear cell carcinoma	525	0.253	4.12e-09	40	56.8	3.2	Loss
KIRP	Kidney renal papillary cell carcinoma	288	0.191	0.0011	17	81.6	1.4	Neutral
LAML	Acute Myeloid Leukemia	166	-0.094	0.231	0	98.8	1.2	Neutral
LGG	Brain Lower Grade Glioma	513	0.268	6.79e-10	13.3	84.8	1.9	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.218	2.78e-05	24.2	65.9	9.9	Neutral
LUAD	Lung adenocarcinoma	512	0.685	3.2e-72	15.8	42.4	41.8	Gain
LUSC	Lung squamous cell carcinoma	498	0.545	8.5e-40	34.7	34.5	30.7	Loss
OV	Ovarian serous cystadenocarcinoma	300	0.448	3.16e-16	37	46.3	16.7	Loss
PAAD	Pancreatic adenocarcinoma	177	0.051	0.501	9	74	16.9	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	0.23	0.00328	13.6	84	2.5	Neutral
PRAD	Prostate adenocarcinoma	491	0.236	1.2e-07	6.3	91	2.6	Neutral
READ	Rectum adenocarcinoma	164	0.368	1.26e-06	39	53.7	7.3	Loss
SARC	Sarcoma	255	0.494	4.22e-17	20	50.2	29.8	Neutral
SKCM	Skin Cutaneous Melanoma	367	0.173	0.000891	29.7	58.3	12	Neutral
STAD	Stomach adenocarcinoma	413	0.368	1e-14	22	65.9	12.1	Neutral
TGCT	Testicular Germ Cell Tumors	150	0.109	0.186	12	54	34	Gain
THCA	Thyroid carcinoma	497	-0.022	0.618	0.2	97.6	2.2	Neutral
THYM	Thymoma	119	0.214	0.0192	2.5	86.6	10.9	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.289	9.38e-12	11.9	79.1	8.9	Neutral

Summary
Symbol	BAZ1A
Name	bromodomain adjacent to zinc finger domain 1A
Aliases	hACF1; ACF1; WALp1; WCRF180; ATP-dependent chromatin remodeling protein; ATP-dependent chromatin-remodeling ......
Location	14q13.1-q13.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

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Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.29	1.32e-09	17	408	-0.003	0.378	NS/NA
BRCA	Breast invasive carcinoma	-0.205	1.17e-09	83	785	-0.005	0.103	NS/NA
CESC	Cervical and endocervical cancers	-0.125	0.0282	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.227	4.84e-05	19	297	0.009	9.66e-06	NS/NA
ESCA	Esophageal carcinoma	-0.322	5.26e-06	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.489	4.56e-05	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.263	5.92e-10	20	522	-0.006	0.484	NS/NA
KIRC	Kidney renal clear cell carcinoma	-0.092	0.0881	24	319	-0.019	0.265	NS/NA
KIRP	Kidney renal papillary cell carcinoma	-0.155	0.00752	23	275	-0.001	0.496	NS/NA
LAML	Acute Myeloid Leukemia	-0.155	0.0433	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	-0.19	1.06e-05	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.228	3.1e-06	41	373	0.025	2.12e-28	NS/NA
LUAD	Lung adenocarcinoma	-0.155	0.000703	21	456	-0.004	0.674	NS/NA
LUSC	Lung squamous cell carcinoma	-0.208	4.66e-05	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	-0.633	0.076	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.158	0.033	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.072	0.326	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.153	4e-04	35	498	0.009	1.93e-13	NS/NA
READ	Rectum adenocarcinoma	-0.216	0.0302	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.282	3.85e-06	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.191	3.11e-05	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.271	1.22e-07	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.057	0.483	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.064	0.129	50	509	-0.001	0.0263	NS/NA
THYM	Thymoma	-0.115	0.208	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.136	0.0034	34	431	-0.002	0.0359	NS/NA

Summary
Symbol	BAZ1A
Name	bromodomain adjacent to zinc finger domain 1A
Aliases	hACF1; ACF1; WALp1; WCRF180; ATP-dependent chromatin remodeling protein; ATP-dependent chromatin-remodeling ......
Location	14q13.1-q13.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Level	Level Name
Adrenal gland	2	Medium
Appendix	3	High
Bone marrow	3	High
Breast	2	Medium
Bronchus	2	Medium
Caudate	2	Medium
Cerebellum	2	Medium
Cerebral cortex	2	Medium
Cervix, uterine	3	High
Colon	2	Medium
Duodenum	2	Medium
Endometrium	2	Medium
Epididymis	2	Medium
Esophagus	2	Medium
Fallopian tube	2	Medium
Gallbladder	2	Medium
Heart muscle	2	Medium
Hippocampus	0	Not detected
Kidney	1	Low
Liver	1	Low
Lung	3	High
Lymph node	2	Medium
Nasopharynx	2	Medium
Oral mucosa	3	High
Ovary	2	Medium
Pancreas	1	Low
Parathyroid gland	2	Medium
Placenta	3	High
Prostate	1	Low
Rectum	3	High
Salivary gland	1	Low
Seminal vesicle	1	Low
Skeletal muscle	2	Medium
Skin	3	High
Small intestine	2	Medium
Smooth muscle	2	Medium
Soft tissue	2	Medium
Spleen	1	Low
Stomach	3	High
Testis	3	High
Thyroid gland	1	Low
Tonsil	2	Medium
Urinary bladder	2	Medium
Vagina	3	High

Summary
Symbol	BAZ1A
Name	bromodomain adjacent to zinc finger domain 1A
Aliases	hACF1; ACF1; WALp1; WCRF180; ATP-dependent chromatin remodeling protein; ATP-dependent chromatin-remodeling ......
Location	14q13.1-q13.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

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Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.988	NS	24476821
BRCA	Breast invasive carcinoma	521	2.18e-13	Significant	23000897
COAD	Colon adenocarcinoma	149	0.00198	Significant	22810696
GBM	Glioblastoma multiforme	157	0.00274	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	0.000732	Significant	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.432	NS	26536169
LGG	Brain Lower Grade Glioma	513	1.37e-08	Significant	26824661
LUAD	Lung adenocarcinoma	230	0.0276	Significant	25079552
LUSC	Lung squamous cell carcinoma	178	0.00202	Significant	22960745
OV	Ovarian serous cystadenocarcinoma	287	0.000344	Significant	21720365
PRAD	Prostate adenocarcinoma	333	0.00267	Significant	26544944
READ	Rectum adenocarcinoma	67	0.352	NS	22810696
SKCM	Skin Cutaneous Melanoma	315	0.152	NS	26091043
STAD	Stomach adenocarcinoma	277	0.000181	Significant	25079317
THCA	Thyroid carcinoma	391	1.82e-11	Significant	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	5.1e-06	Significant	23636398

> Overall survival

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Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	1.035	0.864	NS
BRCA	Breast invasive carcinoma	1079	0.95	0.819	NS
CESC	Cervical and endocervical cancers	291	0.899	0.747	NS
COAD	Colon adenocarcinoma	439	0.862	0.629	NS
ESCA	Esophageal carcinoma	184	1.328	0.397	NS
GBM	Glioblastoma multiforme	158	0.644	0.0917	NS
HNSC	Head and Neck squamous cell carcinoma	518	0.899	0.584	NS
KIRC	Kidney renal clear cell carcinoma	531	1.83	0.00576	Shorter
KIRP	Kidney renal papillary cell carcinoma	287	2.718	0.0137	Shorter
LAML	Acute Myeloid Leukemia	149	0.803	0.459	NS
LGG	Brain Lower Grade Glioma	511	1.219	0.443	NS
LIHC	Liver hepatocellular carcinoma	365	1.707	0.0352	Shorter
LUAD	Lung adenocarcinoma	502	1.096	0.664	NS
LUSC	Lung squamous cell carcinoma	494	0.806	0.274	NS
OV	Ovarian serous cystadenocarcinoma	303	1.127	0.582	NS
PAAD	Pancreatic adenocarcinoma	177	2.48	0.00188	Shorter
PCPG	Pheochromocytoma and Paraganglioma	179	569450957.946	0.0507	NS
PRAD	Prostate adenocarcinoma	497	1.817	0.474	NS
READ	Rectum adenocarcinoma	159	1.203	0.793	NS
SARC	Sarcoma	259	1.643	0.103	NS
SKCM	Skin Cutaneous Melanoma	459	0.616	0.013	Longer
STAD	Stomach adenocarcinoma	388	1.004	0.987	NS
TGCT	Testicular Germ Cell Tumors	134	1.295	0.858	NS
THCA	Thyroid carcinoma	500	0.724	0.694	NS
THYM	Thymoma	119	1274886273.119	0.38	NS
UCEC	Uterine Corpus Endometrial Carcinoma	543	0.728	0.289	NS

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	-0.113	0.023	Lower
BRCA	Breast invasive carcinoma	1071	-0.022	0.478	NS
CESC	Cervical and endocervical cancers	167	-0.029	0.709	NS
COAD	Colon adenocarcinoma	445	-0.067	0.159	NS
ESCA	Esophageal carcinoma	162	-0.002	0.981	NS
HNSC	Head and Neck squamous cell carcinoma	448	-0.021	0.656	NS
KIRC	Kidney renal clear cell carcinoma	531	0.193	7.27e-06	Higher
KIRP	Kidney renal papillary cell carcinoma	260	0.125	0.0436	Higher
LIHC	Liver hepatocellular carcinoma	347	0.017	0.746	NS
LUAD	Lung adenocarcinoma	507	-0.007	0.878	NS
LUSC	Lung squamous cell carcinoma	497	0.045	0.312	NS
OV	Ovarian serous cystadenocarcinoma	302	0.022	0.7	NS
PAAD	Pancreatic adenocarcinoma	176	0.217	0.00388	Higher
READ	Rectum adenocarcinoma	156	0.004	0.961	NS
SKCM	Skin Cutaneous Melanoma	410	-0.043	0.382	NS
STAD	Stomach adenocarcinoma	392	0.055	0.28	NS
TGCT	Testicular Germ Cell Tumors	81	0.024	0.832	NS
THCA	Thyroid carcinoma	499	0.028	0.537	NS
UCEC	Uterine Corpus Endometrial Carcinoma	501	-0.085	0.0562	NS

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	-0.123	0.0428	Lower
HNSC	Head and Neck squamous cell carcinoma	498	-0.033	0.462	NS
KIRC	Kidney renal clear cell carcinoma	525	0.084	0.0552	NS
LGG	Brain Lower Grade Glioma	514	0.201	4.46e-06	Higher
LIHC	Liver hepatocellular carcinoma	366	0.061	0.247	NS
OV	Ovarian serous cystadenocarcinoma	296	0.029	0.625	NS
PAAD	Pancreatic adenocarcinoma	176	0.154	0.0411	Higher
STAD	Stomach adenocarcinoma	406	-0.012	0.813	NS
UCEC	Uterine Corpus Endometrial Carcinoma	534	-0.117	0.00657	Lower

Summary
Symbol	BAZ1A
Name	bromodomain adjacent to zinc finger domain 1A
Aliases	hACF1; ACF1; WALp1; WCRF180; ATP-dependent chromatin remodeling protein; ATP-dependent chromatin-remodeling ......
Location	14q13.1-q13.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	BAZ1A
Name	bromodomain adjacent to zinc finger domain 1A
Aliases	hACF1; ACF1; WALp1; WCRF180; ATP-dependent chromatin remodeling protein; ATP-dependent chromatin-remodeling ......
Location	14q13.1-q13.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for BAZ1A.

Summary
Symbol	BAZ1A
Name	bromodomain adjacent to zinc finger domain 1A
Aliases	hACF1; ACF1; WALp1; WCRF180; ATP-dependent chromatin remodeling protein; ATP-dependent chromatin-remodeling ......
Location	14q13.1-q13.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining [ TOP ]
There is no record for BAZ1A.