Browse BRD2 in pancancer

Summary
SymbolBRD2
Namebromodomain containing 2
Aliases KIAA9001; RING3; D6S113E; NAT; FSRG1; bromodomain-containing 2; FSH; O27.1.1; female sterile homeotic-relate ......
Location6p21.32
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Domain, Function and Classification
> Gene Ontology
> KEGG and Reactome Pathway
> Domain, Function and Classification
 
Domain PF17035 Bromodomain extra-terminal - transcription regulation
PF00439 Bromodomain
Function

May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.

Classification
Class Modification Substrate Product PubMed
Histone modification read # H3K9me2, H3K14me2, H4K5ac, H4K12ac # 18406326
> Gene Ontology
 
Biological Process GO:0006323 DNA packaging
GO:0006333 chromatin assembly or disassembly
GO:0006334 nucleosome assembly
GO:0007283 spermatogenesis
GO:0031497 chromatin assembly
GO:0034728 nucleosome organization
GO:0048232 male gamete generation
GO:0065004 protein-DNA complex assembly
GO:0071103 DNA conformation change
GO:0071824 protein-DNA complex subunit organization
Molecular Function GO:0003682 chromatin binding
GO:0042393 histone binding
GO:0070577 lysine-acetylated histone binding
Cellular Component -
> KEGG and Reactome Pathway
 
KEGG -
Reactome -
Summary
SymbolBRD2
Namebromodomain containing 2
Aliases KIAA9001; RING3; D6S113E; NAT; FSRG1; bromodomain-containing 2; FSH; O27.1.1; female sterile homeotic-relate ......
Location6p21.32
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Mutation landscape in primary tumor tissue from TCGA
> Mutation landscape in cancer cell line from CCLE
> All mutations from COSMIC database V81
> Variations from text mining
> The Cancer Genome Atlas (TCGA)
 
> Cancer Cell Line Encyclopedia (CCLE)
 
> Catalogue of Somatic Mutations in Cancer (COSMIC)
 
COSMIC ID CDS change AA change Mutation Type Anatomical Site
COSM13304c.89G>Ap.G30ESubstitution - MissenseCentral_nervous_system
COSM20582c.1672C>Gp.R558GSubstitution - MissenseStomach
COSM13306c.2141C>Tp.P714LSubstitution - MissenseCentral_nervous_system
COSM13306c.2141C>Tp.P714LSubstitution - MissenseCentral_nervous_system
COSM13304c.89G>Ap.G30ESubstitution - MissenseCentral_nervous_system
COSM21286c.550_552delGAAp.E184_Q185>QDeletion - In frameStomach
COSM13305c.273G>Ap.W91*Substitution - NonsenseCentral_nervous_system
COSM13305c.273G>Ap.W91*Substitution - NonsenseCentral_nervous_system
COSM21286c.550_552delGAAp.E184_Q185>QDeletion - In frameStomach
COSM20582c.1672C>Gp.R558GSubstitution - MissenseStomach
> Text Mining based Variations
 
There is no record for BRD2.
Summary
SymbolBRD2
Namebromodomain containing 2
Aliases KIAA9001; RING3; D6S113E; NAT; FSRG1; bromodomain-containing 2; FSH; O27.1.1; female sterile homeotic-relate ......
Location6p21.32
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Post-translational modification (PTM)
> Post-translational modification (PTM)
 
 Filter By:
Uniprot ID Position Amino Acid Description Upstream Enzyme Affected By Mutation Amino Acid Sequence Variant
P254406TPhosphothreonine-NoNone detected
P2544037SPhosphoserine-NoNone detected
P25440298SPhosphoserine-NoNone detected
P25440301SPhosphoserine-NoNone detected
P25440305SPhosphoserine-NoNone detected
P25440633SPhosphoserine-NoNone detected
Summary
SymbolBRD2
Namebromodomain containing 2
Aliases KIAA9001; RING3; D6S113E; NAT; FSRG1; bromodomain-containing 2; FSH; O27.1.1; female sterile homeotic-relate ......
Location6p21.32
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Expression analysis in primary tumor tissue from TCGA
> Expression level in cancer cell line from CCLE
> Expression level in human normal tissue from HPA
> Text mining based expression change
> The Cancer Genome Atlas (TCGA)
 


  Differential expression analysis for cancers with more than 10 normal samples
Cancer Full Name # N # T Median (N) Median (T) LogFC Adj. P Status
BLCABladder urothelial carcinoma194088.0077.95-0.0550.694NS
BRCABreast invasive carcinoma11211008.078.1860.1697.38e-05NS
CESCCervical and endocervical cancers33068.0038.221NANANA
COADColon adenocarcinoma414597.7067.80.0620.4NS
ESCAEsophageal carcinoma111858.0177.9860.0130.94NS
GBMGlioblastoma multiforme51667.827.812NANANA
HNSCHead and Neck squamous cell carcinoma445227.7397.8210.1440.064NS
KIRCKidney renal clear cell carcinoma725347.7917.846-0.0120.831NS
KIRPKidney renal papillary cell carcinoma322917.8837.508-0.4071.3e-07NS
LAMLAcute Myeloid Leukemia0173NA8.599NANANA
LGGBrain Lower Grade Glioma0530NA7.978NANANA
LIHCLiver hepatocellular carcinoma503737.127.1490.0450.62NS
LUADLung adenocarcinoma595178.0127.941-0.0010.99NS
LUSCLung squamous cell carcinoma515018.0538.1170.0670.312NS
OVOvarian serous cystadenocarcinoma0307NA8.22NANANA
PAADPancreatic adenocarcinoma41797.7997.759NANANA
PCPGPheochromocytoma and Paraganglioma31847.7448.165NANANA
PRADProstate adenocarcinoma524988.1138.3190.2399.81e-05NS
READRectum adenocarcinoma101677.5787.7940.2230.172NS
SARCSarcoma22637.3967.727NANANA
SKCMSkin Cutaneous Melanoma14728.1918.165NANANA
STADStomach adenocarcinoma354157.9337.922-0.0280.754NS
TGCTTesticular Germ Cell Tumors0156NA8.313NANANA
THCAThyroid carcinoma595098.6498.178-0.4455.49e-22NS
THYMThymoma21208.5028.452NANANA
UCECUterine Corpus Endometrial Carcinoma355467.9947.819-0.1730.0407NS
> Cancer Cell Line Encyclopedia (CCLE)
 



Tissue Cell Line Expression Level (Microarray)
Autonomic ganglia CHP126 9.2
Autonomic ganglia CHP212 9.6
Autonomic ganglia IMR32 11.4
Autonomic ganglia KELLY 9.8
Autonomic ganglia KPNRTBM1 10.1
Autonomic ganglia KPNSI9S 9.2
Autonomic ganglia KPNYN 10.2
Autonomic ganglia MHHNB11 9.7
Autonomic ganglia NB1 10.1
Autonomic ganglia NH6 9.6
Autonomic ganglia SHSY5Y 9.7
Autonomic ganglia SIMA 9.8
Autonomic ganglia SKNAS 9.5
Autonomic ganglia SKNBE2 10.1
Autonomic ganglia SKNDZ 9.5
Autonomic ganglia SKNFI 9.8
Autonomic ganglia SKNSH 9
Biliary tract HUCCT1 9.3
Biliary tract HUH28 8.7
Biliary tract SNU1079 9.8
Biliary tract SNU1196 9.7
Biliary tract SNU245 10.1
Biliary tract SNU308 10
Biliary tract SNU478 10.3
Bone 143B 9.7
Bone A673 10.2
Bone CADOES1 10.7
Bone CAL78 10
Bone G292CLONEA141B1 9.4
Bone HOS 9.8
Bone HS706T 9.3
Bone HS737T 9
Bone HS819T 9.2
Bone HS821T 9.8
Bone HS822T 9.3
Bone HS863T 9.8
Bone HS870T 9
Bone HS888T 10.1
Bone MG63 10.9
Bone MHHES1 10.8
Bone OUMS27 9
Bone RDES 10.2
Bone SJSA1 9.5
Bone SKES1 9.7
Bone SKNMC 10.7
Bone SW1353 9.4
Bone T173 9.4
Bone TC71 9.8
Bone U2OS 10.1
Breast AU565 10.6
Breast BT20 10.5
Breast BT474 10.2
Breast BT483 10.8
Breast BT549 9.8
Breast CAL120 9.9
Breast CAL148 10
Breast CAL51 10.4
Breast CAL851 9.6
Breast CAMA1 10.6
Breast DU4475 9.6
Breast EFM192A 10.6
Breast EFM19 10.6
Breast EVSAT 10.5
Breast HCC1143 10.2
Breast HCC1187 10
Breast HCC1395 10
Breast HCC1419 10.7
Breast HCC1428 10.2
Breast HCC1500 8.8
Breast HCC1569 10.2
Breast HCC1599 9.8
Breast HCC1806 10.5
Breast HCC1937 10.1
Breast HCC1954 10.3
Breast HCC202 9.8
Breast HCC2157 9.3
Breast HCC2218 9.7
Breast HCC38 10.3
Breast HCC70 9.5
Breast HDQP1 9.6
Breast HMC18 9.9
Breast HS274T 9.8
Breast HS281T 9.9
Breast HS343T 10
Breast HS578T 10.1
Breast HS606T 9.2
Breast HS739T 9.3
Breast HS742T 9.4
Breast JIMT1 9.9
Breast KPL1 10.4
Breast MCF7 10.5
Breast MDAMB134VI 9.5
Breast MDAMB157 9.4
Breast MDAMB175VII 9.1
Breast MDAMB231 9.9
Breast MDAMB361 10
Breast MDAMB415 10.5
Breast MDAMB436 9.5
Breast MDAMB453 10.3
Breast MDAMB468 10.1
Breast SKBR3 10.4
Breast T47D 9.5
Breast UACC812 10.4
Breast UACC893 9.4
Breast YMB1 9.7
Breast ZR751 8.9
Breast ZR7530 10.4
Central nervous system 1321N1 9.5
Central nervous system 42MGBA 9.6
Central nervous system 8MGBA 10.1
Central nervous system A172 9.1
Central nervous system AM38 9.2
Central nervous system BECKER 9.1
Central nervous system CAS1 9.5
Central nervous system CCFSTTG1 9.8
Central nervous system D283MED 10.5
Central nervous system D341MED 10.5
Central nervous system DAOY 9.9
Central nervous system DBTRG05MG 8.9
Central nervous system DKMG 9.3
Central nervous system GAMG 9.9
Central nervous system GB1 10.4
Central nervous system GI1 9.7
Central nervous system GMS10 10.6
Central nervous system GOS3 9.9
Central nervous system H4 9.8
Central nervous system HS683 9.7
Central nervous system KALS1 9.9
Central nervous system KG1C 8.5
Central nervous system KNS42 10.2
Central nervous system KNS60 9.5
Central nervous system KNS81 9.4
Central nervous system KS1 9.7
Central nervous system LN18 10.5
Central nervous system LN229 9.7
Central nervous system M059K 10
Central nervous system MOGGCCM 10
Central nervous system MOGGUVW 9.8
Central nervous system NMCG1 9.3
Central nervous system ONS76 9.4
Central nervous system SF126 9
Central nervous system SF295 9.7
Central nervous system SNB19 9.8
Central nervous system SNU1105 10
Central nervous system SNU201 10.4
Central nervous system SNU466 10
Central nervous system SNU489 10.5
Central nervous system SNU626 9.8
Central nervous system SNU738 9.9
Central nervous system SW1088 9.3
Central nervous system SW1783 9.2
Central nervous system T98G 9.8
Central nervous system TM31 10.2
Central nervous system U118MG 10
Central nervous system U138MG 10.3
Central nervous system U251MG 9.4
Central nervous system U87MG 9.2
Central nervous system YH13 10
Central nervous system YKG1 9.5
Endometrium AN3CA 10.3
Endometrium COLO684 10.8
Endometrium EFE184 9.3
Endometrium EN 10.5
Endometrium ESS1 10.7
Endometrium HEC108 9.9
Endometrium HEC151 10
Endometrium HEC1A 9.8
Endometrium HEC1B 10.6
Endometrium HEC251 10.1
Endometrium HEC265 9.9
Endometrium HEC50B 9.1
Endometrium HEC59 9.5
Endometrium HEC6 9.9
Endometrium ISHIKAWAHERAKLIO02ER 9.9
Endometrium JHUEM1 9.2
Endometrium JHUEM2 10.2
Endometrium JHUEM3 10
Endometrium KLE 9.7
Endometrium MFE280 10.4
Endometrium MFE296 10.4
Endometrium MFE319 10.1
Endometrium RL952 10.3
Endometrium SNGM 10
Endometrium SNU1077 9.6
Endometrium SNU685 9.8
Endometrium TEN 10.2
Haematopoietic and lymphoid 697 10.5
Haematopoietic and lymphoid A3KAW 9.8
Haematopoietic and lymphoid A4FUK 10.1
Haematopoietic and lymphoid ALLSIL 10.6
Haematopoietic and lymphoid AML193 10.9
Haematopoietic and lymphoid AMO1 10.1
Haematopoietic and lymphoid BCP1 10
Haematopoietic and lymphoid BDCM 9.9
Haematopoietic and lymphoid BL41 10.4
Haematopoietic and lymphoid BL70 10.1
Haematopoietic and lymphoid BV173 9.8
Haematopoietic and lymphoid CA46 10.7
Haematopoietic and lymphoid CI1 9.9
Haematopoietic and lymphoid CMK115 9.6
Haematopoietic and lymphoid CMK86 10.1
Haematopoietic and lymphoid CMK 10
Haematopoietic and lymphoid CMLT1 10.1
Haematopoietic and lymphoid COLO775 10.5
Haematopoietic and lymphoid DAUDI 10
Haematopoietic and lymphoid DB 9.7
Haematopoietic and lymphoid DEL 11
Haematopoietic and lymphoid DND41 10.1
Haematopoietic and lymphoid DOHH2 10.3
Haematopoietic and lymphoid EB1 10.2
Haematopoietic and lymphoid EB2 10.4
Haematopoietic and lymphoid EHEB 9.7
Haematopoietic and lymphoid EJM 10.7
Haematopoietic and lymphoid EM2 11.1
Haematopoietic and lymphoid EOL1 10.1
Haematopoietic and lymphoid F36P 10.4
Haematopoietic and lymphoid GA10 10.4
Haematopoietic and lymphoid GDM1 9.7
Haematopoietic and lymphoid GRANTA519 9.7
Haematopoietic and lymphoid HDLM2 9.9
Haematopoietic and lymphoid HDMYZ 9.3
Haematopoietic and lymphoid HEL9217 10
Haematopoietic and lymphoid HEL 10.4
Haematopoietic and lymphoid HH 9
Haematopoietic and lymphoid HL60 11.2
Haematopoietic and lymphoid HPBALL 10.1
Haematopoietic and lymphoid HS604T 9.7
Haematopoietic and lymphoid HS611T 9.8
Haematopoietic and lymphoid HS616T 9.4
Haematopoietic and lymphoid HS751T 9
Haematopoietic and lymphoid HT 10.3
Haematopoietic and lymphoid HTK 9.8
Haematopoietic and lymphoid HUNS1 9.9
Haematopoietic and lymphoid HUT102 9.9
Haematopoietic and lymphoid HUT78 10.1
Haematopoietic and lymphoid JEKO1 9.8
Haematopoietic and lymphoid JK1 10.4
Haematopoietic and lymphoid JM1 10.3
Haematopoietic and lymphoid JURKAT 10.8
Haematopoietic and lymphoid JURLMK1 9.6
Haematopoietic and lymphoid JVM2 10.2
Haematopoietic and lymphoid JVM3 10.7
Haematopoietic and lymphoid K562 10.1
Haematopoietic and lymphoid KARPAS299 10
Haematopoietic and lymphoid KARPAS422 10.7
Haematopoietic and lymphoid KARPAS620 10.5
Haematopoietic and lymphoid KASUMI1 9.5
Haematopoietic and lymphoid KASUMI2 9.8
Haematopoietic and lymphoid KASUMI6 9.2
Haematopoietic and lymphoid KCL22 10.6
Haematopoietic and lymphoid KE37 10
Haematopoietic and lymphoid KE97 9.8
Haematopoietic and lymphoid KG1 10
Haematopoietic and lymphoid KHM1B 10.4
Haematopoietic and lymphoid KIJK 10.1
Haematopoietic and lymphoid KMH2 10.7
Haematopoietic and lymphoid KMM1 10.7
Haematopoietic and lymphoid KMS11 10.1
Haematopoietic and lymphoid KMS12BM 10.4
Haematopoietic and lymphoid KMS18 10.3
Haematopoietic and lymphoid KMS20 10.3
Haematopoietic and lymphoid KMS21BM 9.9
Haematopoietic and lymphoid KMS26 9.9
Haematopoietic and lymphoid KMS27 9.8
Haematopoietic and lymphoid KMS28BM 9.9
Haematopoietic and lymphoid KMS34 10.2
Haematopoietic and lymphoid KO52 10.2
Haematopoietic and lymphoid KOPN8 10.2
Haematopoietic and lymphoid KU812 10.9
Haematopoietic and lymphoid KYO1 9.9
Haematopoietic and lymphoid L1236 10.5
Haematopoietic and lymphoid L363 10.6
Haematopoietic and lymphoid L428 10.1
Haematopoietic and lymphoid L540 10
Haematopoietic and lymphoid LAMA84 10.2
Haematopoietic and lymphoid LOUCY 10.5
Haematopoietic and lymphoid LP1 9.9
Haematopoietic and lymphoid M07E 10.2
Haematopoietic and lymphoid MC116 10.3
Haematopoietic and lymphoid ME1 9.6
Haematopoietic and lymphoid MEC1 10.2
Haematopoietic and lymphoid MEC2 10.1
Haematopoietic and lymphoid MEG01 10
Haematopoietic and lymphoid MHHCALL2 10.6
Haematopoietic and lymphoid MHHCALL3 10
Haematopoietic and lymphoid MHHCALL4 10.3
Haematopoietic and lymphoid MINO 10
Haematopoietic and lymphoid MJ 9.9
Haematopoietic and lymphoid MM1S 10.5
Haematopoietic and lymphoid MOLM13 10.5
Haematopoietic and lymphoid MOLM16 10
Haematopoietic and lymphoid MOLM6 9.4
Haematopoietic and lymphoid MOLP2 10.4
Haematopoietic and lymphoid MOLP8 10.6
Haematopoietic and lymphoid MOLT13 10.2
Haematopoietic and lymphoid MOLT16 10.8
Haematopoietic and lymphoid MOLT4 10.5
Haematopoietic and lymphoid MONOMAC1 9.6
Haematopoietic and lymphoid MONOMAC6 10.3
Haematopoietic and lymphoid MOTN1 10.6
Haematopoietic and lymphoid MUTZ5 10
Haematopoietic and lymphoid MV411 10.5
Haematopoietic and lymphoid NALM19 9.8
Haematopoietic and lymphoid NALM1 9.9
Haematopoietic and lymphoid NALM6 9.8
Haematopoietic and lymphoid NAMALWA 10.7
Haematopoietic and lymphoid NB4 10.3
Haematopoietic and lymphoid NCIH929 9.6
Haematopoietic and lymphoid NCO2 10.1
Haematopoietic and lymphoid NOMO1 9.9
Haematopoietic and lymphoid NUDHL1 10.5
Haematopoietic and lymphoid NUDUL1 10.2
Haematopoietic and lymphoid OCIAML2 9.2
Haematopoietic and lymphoid OCIAML3 10.2
Haematopoietic and lymphoid OCIAML5 9.3
Haematopoietic and lymphoid OCILY10 10.4
Haematopoietic and lymphoid OCILY19 10.2
Haematopoietic and lymphoid OCILY3 9.2
Haematopoietic and lymphoid OCIM1 10.6
Haematopoietic and lymphoid OPM2 10.6
Haematopoietic and lymphoid P12ICHIKAWA 10.8
Haematopoietic and lymphoid P31FUJ 9.4
Haematopoietic and lymphoid P3HR1 10.2
Haematopoietic and lymphoid PCM6 10.3
Haematopoietic and lymphoid PEER 10.1
Haematopoietic and lymphoid PF382 10
Haematopoietic and lymphoid PFEIFFER 10.4
Haematopoietic and lymphoid PL21 9.6
Haematopoietic and lymphoid RAJI 10.1
Haematopoietic and lymphoid RCHACV 10
Haematopoietic and lymphoid REC1 10.2
Haematopoietic and lymphoid REH 9.9
Haematopoietic and lymphoid RI1 10.4
Haematopoietic and lymphoid RL 9.8
Haematopoietic and lymphoid RPMI8226 9.6
Haematopoietic and lymphoid RPMI8402 10.9
Haematopoietic and lymphoid RS411 10.1
Haematopoietic and lymphoid SEM 9.7
Haematopoietic and lymphoid SET2 10.1
Haematopoietic and lymphoid SIGM5 10.3
Haematopoietic and lymphoid SKM1 9.4
Haematopoietic and lymphoid SKMM2 9.9
Haematopoietic and lymphoid SR786 9.9
Haematopoietic and lymphoid ST486 9.8
Haematopoietic and lymphoid SUDHL10 9.7
Haematopoietic and lymphoid SUDHL1 10.6
Haematopoietic and lymphoid SUDHL4 9.9
Haematopoietic and lymphoid SUDHL5 10.8
Haematopoietic and lymphoid SUDHL6 11.4
Haematopoietic and lymphoid SUDHL8 10.2
Haematopoietic and lymphoid SUPB15 10.3
Haematopoietic and lymphoid SUPHD1 9
Haematopoietic and lymphoid SUPM2 10.1
Haematopoietic and lymphoid SUPT11 10.4
Haematopoietic and lymphoid SUPT1 10.6
Haematopoietic and lymphoid TALL1 10.5
Haematopoietic and lymphoid TF1 10.1
Haematopoietic and lymphoid THP1 10.2
Haematopoietic and lymphoid TO175T 9.5
Haematopoietic and lymphoid TOLEDO 10
Haematopoietic and lymphoid U266B1 9.7
Haematopoietic and lymphoid U937 9.3
Haematopoietic and lymphoid UT7 9.5
Haematopoietic and lymphoid WSUDLCL2 10.1
Kidney 769P 9.8
Kidney 786O 9.6
Kidney A498 8.6
Kidney A704 9
Kidney ACHN 8.6
Kidney BFTC909 9.8
Kidney CAKI1 8.9
Kidney CAKI2 9.6
Kidney CAL54 9.3
Kidney KMRC1 8.5
Kidney KMRC20 9.5
Kidney KMRC2 9.4
Kidney KMRC3 9.5
Kidney OSRC2 9.1
Kidney RCC10RGB 9.7
Kidney SNU1272 9.6
Kidney SNU349 9.6
Kidney TUHR10TKB 9.5
Kidney TUHR14TKB 9.2
Kidney TUHR4TKB 9.5
Kidney VMRCRCW 9.5
Kidney VMRCRCZ 9.8
Large intestine C2BBE1 9.3
Large intestine CCK81 10.6
Large intestine CL11 9.7
Large intestine CL14 9.9
Large intestine CL34 10.1
Large intestine CL40 9.6
Large intestine COLO205 9.2
Large intestine COLO320 10.4
Large intestine COLO678 10.1
Large intestine CW2 9
Large intestine DLD1 10.1
Large intestine GP2D 9.6
Large intestine HCC56 10
Large intestine HCT116 10.5
Large intestine HCT15 10.3
Large intestine HS675T 9.2
Large intestine HS698T 9
Large intestine HT115 10.5
Large intestine HT29 10.2
Large intestine HT55 9
Large intestine KM12 9.1
Large intestine LOVO 9.7
Large intestine LS1034 9.9
Large intestine LS123 10.2
Large intestine LS180 9.9
Large intestine LS411N 9.7
Large intestine LS513 9.2
Large intestine MDST8 8.9
Large intestine NCIH508 10.3
Large intestine NCIH716 9.7
Large intestine NCIH747 9.8
Large intestine OUMS23 9.9
Large intestine RCM1 10.6
Large intestine RKO 9.7
Large intestine SKCO1 9.4
Large intestine SNU1040 10.7
Large intestine SNU1197 10.5
Large intestine SNU175 10.3
Large intestine SNU283 9.4
Large intestine SNU407 11
Large intestine SNU503 10.4
Large intestine SNU61 10.1
Large intestine SNU81 11.1
Large intestine SNUC1 9.5
Large intestine SNUC2A 9.7
Large intestine SNUC4 10.1
Large intestine SNUC5 10.4
Large intestine SW1116 9.8
Large intestine SW1417 9.9
Large intestine SW1463 10.1
Large intestine SW403 9.7
Large intestine SW480 9
Large intestine SW48 10.7
Large intestine SW620 9.9
Large intestine SW837 8.8
Large intestine SW948 9.3
Large intestine T84 10.3
Liver ALEXANDERCELLS 9.7
Liver C3A 9.6
Liver HEP3B217 10.1
Liver HEPG2 9.8
Liver HLE 9.3
Liver HLF 9.4
Liver HUH1 10.1
Liver HUH6 9.3
Liver HUH7 8.9
Liver JHH1 9.4
Liver JHH2 9.5
Liver JHH4 9.3
Liver JHH5 9.7
Liver JHH6 9.6
Liver JHH7 9.6
Liver LI7 9.8
Liver PLCPRF5 9.8
Liver SKHEP1 9.6
Liver SNU182 9.4
Liver SNU387 9.8
Liver SNU398 10.6
Liver SNU423 10
Liver SNU449 9.7
Liver SNU475 10.4
Liver SNU761 9.4
Liver SNU878 9.1
Liver SNU886 9.9
Lung A549 9.3
Lung ABC1 9.6
Lung BEN 10.2
Lung CAL12T 9.4
Lung CALU1 9.8
Lung CALU3 10.8
Lung CALU6 9.6
Lung CHAGOK1 9.4
Lung COLO668 10.3
Lung COLO699 10.4
Lung CORL105 10.2
Lung CORL23 10.1
Lung CORL24 10
Lung CORL279 10.4
Lung CORL311 9.8
Lung CORL47 10.9
Lung CORL51 10.9
Lung CORL88 10.6
Lung CORL95 10.5
Lung CPCN 10.8
Lung DMS114 10.4
Lung DMS153 9.7
Lung DMS273 10.3
Lung DMS454 9.7
Lung DMS53 10.1
Lung DMS79 10.3
Lung DV90 9.9
Lung EBC1 9.8
Lung EPLC272H 9.7
Lung HARA 9.7
Lung HCC1171 9.6
Lung HCC1195 9.1
Lung HCC15 10.1
Lung HCC2279 9.6
Lung HCC2935 10.9
Lung HCC33 10.8
Lung HCC366 9.9
Lung HCC4006 9.3
Lung HCC44 10.9
Lung HCC78 9.9
Lung HCC827 9.2
Lung HCC95 9.7
Lung HLC1 9.6
Lung HLFA 9.2
Lung HS229T 9.3
Lung HS618T 9.3
Lung IALM 9.8
Lung KNS62 10.2
Lung LC1F 10.1
Lung LC1SQSF 9.7
Lung LCLC103H 10.1
Lung LCLC97TM1 10.9
Lung LK2 10
Lung LOUNH91 9.8
Lung LU65 9.8
Lung LU99 10.1
Lung LUDLU1 10.2
Lung LXF289 10.3
Lung MORCPR 10.5
Lung NCIH1048 10.2
Lung NCIH1092 9.1
Lung NCIH1105 10.3
Lung NCIH1155 10.4
Lung NCIH1184 9.9
Lung NCIH1299 10.8
Lung NCIH1339 10.1
Lung NCIH1341 10
Lung NCIH1355 9.9
Lung NCIH1373 10.6
Lung NCIH1385 9.4
Lung NCIH1395 10.1
Lung NCIH1435 10.6
Lung NCIH1436 10.1
Lung NCIH1437 10
Lung NCIH146 9.5
Lung NCIH1563 10.1
Lung NCIH1568 9.8
Lung NCIH1573 9.6
Lung NCIH1581 10.8
Lung NCIH1618 10.3
Lung NCIH1623 9.9
Lung NCIH1648 9.9
Lung NCIH1650 9.6
Lung NCIH1651 8.8
Lung NCIH1666 9.6
Lung NCIH1693 9.4
Lung NCIH1694 9.7
Lung NCIH1703 10.1
Lung NCIH1734 10.3
Lung NCIH1755 9.7
Lung NCIH1781 10.3
Lung NCIH1792 9.5
Lung NCIH1793 8.9
Lung NCIH1836 10
Lung NCIH1838 9.4
Lung NCIH1869 10.6
Lung NCIH1876 10.3
Lung NCIH1915 9.9
Lung NCIH1930 10.1
Lung NCIH1944 10.2
Lung NCIH1963 9.9
Lung NCIH196 10
Lung NCIH1975 9.6
Lung NCIH2009 9.8
Lung NCIH2023 9.4
Lung NCIH2029 10.5
Lung NCIH2030 10.1
Lung NCIH2066 10.9
Lung NCIH2081 10.4
Lung NCIH2085 10.2
Lung NCIH2087 9.7
Lung NCIH209 10.6
Lung NCIH2106 8.3
Lung NCIH2110 9
Lung NCIH211 10.4
Lung NCIH2122 9.5
Lung NCIH2126 9.5
Lung NCIH2141 9.7
Lung NCIH2170 10.1
Lung NCIH2171 10.8
Lung NCIH2172 9.8
Lung NCIH2196 10.1
Lung NCIH2227 9.6
Lung NCIH2228 9.3
Lung NCIH226 9.4
Lung NCIH2286 9.5
Lung NCIH2291 9.8
Lung NCIH2342 10.4
Lung NCIH2347 9.6
Lung NCIH23 10.5
Lung NCIH2405 10.1
Lung NCIH2444 10.3
Lung NCIH292 10
Lung NCIH322 10.2
Lung NCIH3255 10.4
Lung NCIH358 10.1
Lung NCIH441 10.6
Lung NCIH446 10.2
Lung NCIH460 9.1
Lung NCIH510 10
Lung NCIH520 10.1
Lung NCIH522 10
Lung NCIH524 9.7
Lung NCIH526 10.3
Lung NCIH596 10.3
Lung NCIH647 9.8
Lung NCIH650 10.1
Lung NCIH661 9.6
Lung NCIH69 10.4
Lung NCIH727 9.8
Lung NCIH810 9.7
Lung NCIH82 10.2
Lung NCIH838 9.4
Lung NCIH841 10.2
Lung NCIH854 10.5
Lung NCIH889 10.3
Lung PC14 9.3
Lung RERFLCAD1 10.3
Lung RERFLCAD2 9.3
Lung RERFLCAI 9.9
Lung RERFLCKJ 10.3
Lung RERFLCMS 9.5
Lung RERFLCSQ1 9.6
Lung SBC5 9.6
Lung SCLC21H 11.5
Lung SHP77 9.7
Lung SKLU1 10.4
Lung SKMES1 9.2
Lung SQ1 10.5
Lung SW1271 10.4
Lung SW1573 9.6
Lung SW900 10
Lung VMRCLCD 10.8
Lung VMRCLCP 10.1
Oesophagus COLO680N 9.9
Oesophagus ECGI10 10.5
Oesophagus KYSE140 9.9
Oesophagus KYSE150 9.3
Oesophagus KYSE180 10
Oesophagus KYSE270 10.3
Oesophagus KYSE30 10
Oesophagus KYSE410 10
Oesophagus KYSE450 10.2
Oesophagus KYSE510 9.8
Oesophagus KYSE520 9.4
Oesophagus KYSE70 9.2
Oesophagus OE19 9.9
Oesophagus OE33 9.2
Oesophagus TE10 11
Oesophagus TE11 9.9
Oesophagus TE14 10.1
Oesophagus TE15 10
Oesophagus TE1 9.5
Oesophagus TE4 10.2
Oesophagus TE5 9.7
Oesophagus TE6 10.2
Oesophagus TE8 9.7
Oesophagus TE9 9.7
Oesophagus TT 10.2
Ovary 59M 9.7
Ovary A2780 10.4
Ovary CAOV3 9.8
Ovary CAOV4 9.4
Ovary COLO704 10.3
Ovary COV318 9.9
Ovary COV362 9.3
Ovary COV434 9.9
Ovary COV504 9
Ovary COV644 9.3
Ovary EFO21 10.7
Ovary EFO27 9.8
Ovary ES2 9.7
Ovary FUOV1 9.9
Ovary HEYA8 9.1
Ovary HS571T 9.5
Ovary IGROV1 10.1
Ovary JHOC5 10
Ovary JHOM1 10.5
Ovary JHOM2B 10.4
Ovary JHOS2 9.2
Ovary JHOS4 9.5
Ovary KURAMOCHI 10.5
Ovary MCAS 9.9
Ovary NIHOVCAR3 10
Ovary OAW28 9.8
Ovary OAW42 9.7
Ovary OC314 9.4
Ovary OC316 9.4
Ovary ONCODG1 9.3
Ovary OV56 10.5
Ovary OV7 9.6
Ovary OV90 10.4
Ovary OVCAR4 9.2
Ovary OVCAR8 10.1
Ovary OVISE 9.4
Ovary OVK18 10
Ovary OVKATE 8.5
Ovary OVMANA 9.5
Ovary OVSAHO 9.4
Ovary OVTOKO 8.7
Ovary RMGI 10
Ovary RMUGS 9.8
Ovary SKOV3 10.1
Ovary SNU119 10.2
Ovary SNU840 10.2
Ovary SNU8 9.6
Ovary TOV112D 10.6
Ovary TOV21G 9.1
Ovary TYKNU 9.4
Pancreas ASPC1 9.7
Pancreas BXPC3 9.4
Pancreas CAPAN1 10.5
Pancreas CAPAN2 9.2
Pancreas CFPAC1 10.6
Pancreas DANG 9.6
Pancreas HPAC 10.5
Pancreas HPAFII 9.7
Pancreas HS766T 9.2
Pancreas HUPT3 9.5
Pancreas HUPT4 10.2
Pancreas KCIMOH1 9.2
Pancreas KLM1 10.2
Pancreas KP2 9.9
Pancreas KP3 9.3
Pancreas KP4 9.9
Pancreas L33 10.1
Pancreas MIAPACA2 10.4
Pancreas PANC0203 10
Pancreas PANC0213 11
Pancreas PANC0327 9.9
Pancreas PANC0403 9.1
Pancreas PANC0504 9.7
Pancreas PANC0813 10.5
Pancreas PANC1005 10.6
Pancreas PANC1 9.5
Pancreas PATU8902 9.7
Pancreas PATU8988S 9.5
Pancreas PATU8988T 10.9
Pancreas PK1 9.2
Pancreas PK45H 9.2
Pancreas PK59 10.7
Pancreas PL45 10.2
Pancreas PSN1 9.4
Pancreas QGP1 9.8
Pancreas SNU213 10
Pancreas SNU324 10
Pancreas SNU410 10.4
Pancreas SU8686 10.6
Pancreas SUIT2 9.7
Pancreas SW1990 9.2
Pancreas T3M4 10.4
Pancreas TCCPAN2 10.2
Pancreas YAPC 9.7
Pleura ACCMESO1 9.1
Pleura DM3 9
Pleura ISTMES1 9.6
Pleura ISTMES2 9.6
Pleura JL1 9.7
Pleura MPP89 9.4
Pleura MSTO211H 9.4
Pleura NCIH2052 9
Pleura NCIH2452 9.6
Pleura NCIH28 9.8
Prostate 22RV1 9.3
Prostate DU145 9.7
Prostate LNCAPCLONEFGC 10.1
Prostate MDAPCA2B 10.5
Prostate NCIH660 10.3
Prostate PC3 9.4
Prostate VCAP 10.4
Salivary gland A253 8.3
Salivary gland YD15 10
Skin A101D 9.6
Skin A2058 10.6
Skin A375 9.7
Skin C32 10.2
Skin CHL1 10
Skin CJM 9.9
Skin COLO679 10.3
Skin COLO741 10.1
Skin COLO783 8.8
Skin COLO792 9.8
Skin COLO800 10.2
Skin COLO818 9.5
Skin COLO829 10.6
Skin COLO849 10.2
Skin G361 9.4
Skin GRM 9.6
Skin HMCB 10.2
Skin HS294T 9.9
Skin HS600T 9.2
Skin HS688AT 9.5
Skin HS695T 9.2
Skin HS839T 9.1
Skin HS852T 9.9
Skin HS895T 9.1
Skin HS934T 9.8
Skin HS936T 9
Skin HS939T 9.9
Skin HS940T 9.6
Skin HS944T 10.5
Skin HT144 9.8
Skin IGR1 9.6
Skin IGR37 9.4
Skin IGR39 9.2
Skin IPC298 9.8
Skin K029AX 9.7
Skin LOXIMVI 10.7
Skin MALME3M 9.8
Skin MDAMB435S 9.3
Skin MELHO 9.8
Skin MELJUSO 9.6
Skin MEWO 9.5
Skin RPMI7951 9.4
Skin RVH421 9.6
Skin SH4 10.7
Skin SKMEL1 9.3
Skin SKMEL24 9.8
Skin SKMEL28 9.7
Skin SKMEL2 9.1
Skin SKMEL30 9.9
Skin SKMEL31 9.6
Skin SKMEL3 9.5
Skin SKMEL5 10
Skin UACC257 10.1
Skin UACC62 9.6
Skin WM115 10.1
Skin WM1799 9.3
Skin WM2664 9.5
Skin WM793 10
Skin WM88 9.3
Skin WM983B 9.4
Small intestine HUTU80 9.9
Soft tissue A204 9.4
Soft tissue G401 9.8
Soft tissue G402 9.5
Soft tissue GCT 10.2
Soft tissue HS729 10
Soft tissue HT1080 9.9
Soft tissue KYM1 10.1
Soft tissue MESSA 9.8
Soft tissue RD 9.1
Soft tissue RH30 10.1
Soft tissue RH41 9.2
Soft tissue RKN 9.6
Soft tissue S117 10.4
Soft tissue SJRH30 10.3
Soft tissue SKLMS1 9.6
Soft tissue SKUT1 10.2
Soft tissue TE125T 9.2
Soft tissue TE159T 9.4
Soft tissue TE441T 10.4
Soft tissue TE617T 10
Stomach 2313287 10.7
Stomach AGS 9.6
Stomach AZ521 10.2
Stomach ECC10 10.2
Stomach ECC12 10.2
Stomach FU97 9.2
Stomach GCIY 9.3
Stomach GSS 10.8
Stomach GSU 10.5
Stomach HGC27 9.7
Stomach HS746T 10
Stomach HUG1N 10.5
Stomach IM95 9.9
Stomach KATOIII 9.7
Stomach KE39 9.7
Stomach LMSU 10.3
Stomach MKN1 8.8
Stomach MKN45 10.1
Stomach MKN74 10.2
Stomach MKN7 9.6
Stomach NCCSTCK140 10.3
Stomach NCIN87 9.2
Stomach NUGC2 9.5
Stomach NUGC3 10
Stomach NUGC4 9.8
Stomach OCUM1 10
Stomach RERFGC1B 10
Stomach SH10TC 9.3
Stomach SNU16 10
Stomach SNU1 10.2
Stomach SNU216 10.3
Stomach SNU520 10.2
Stomach SNU5 9.9
Stomach SNU601 10.4
Stomach SNU620 9.8
Stomach SNU668 9.1
Stomach SNU719 10.2
Stomach TGBC11TKB 10.4
Thyroid 8305C 9.5
Thyroid 8505C 9.8
Thyroid BCPAP 10.2
Thyroid BHT101 10.8
Thyroid CAL62 10.8
Thyroid CGTHW1 9.7
Thyroid FTC133 9
Thyroid FTC238 8.8
Thyroid ML1 9.3
Thyroid SW579 9.3
Thyroid TT2609C02 10
Thyroid TT 9.4
Upper aerodigestive tract BHY 10.3
Upper aerodigestive tract BICR16 10.3
Upper aerodigestive tract BICR18 9.5
Upper aerodigestive tract BICR22 10
Upper aerodigestive tract BICR31 9.1
Upper aerodigestive tract BICR56 10.5
Upper aerodigestive tract BICR6 9.8
Upper aerodigestive tract CAL27 10
Upper aerodigestive tract CAL33 10.6
Upper aerodigestive tract DETROIT562 9.7
Upper aerodigestive tract FADU 10
Upper aerodigestive tract HS840T 9.3
Upper aerodigestive tract HSC2 10
Upper aerodigestive tract HSC3 9.4
Upper aerodigestive tract HSC4 9.9
Upper aerodigestive tract PECAPJ15 9.5
Upper aerodigestive tract PECAPJ34CLONEC12 9.7
Upper aerodigestive tract PECAPJ41CLONED2 9.6
Upper aerodigestive tract PECAPJ49 9.9
Upper aerodigestive tract SCC15 10
Upper aerodigestive tract SCC25 9.9
Upper aerodigestive tract SCC4 10
Upper aerodigestive tract SCC9 10.5
Upper aerodigestive tract SNU1076 9.7
Upper aerodigestive tract SNU1214 9.6
Upper aerodigestive tract SNU46 10.1
Upper aerodigestive tract SNU899 10
Upper aerodigestive tract YD10B 10.3
Upper aerodigestive tract YD38 9.6
Upper aerodigestive tract YD8 9.2
Urinary tract 5637 9.4
Urinary tract 639V 10.6
Urinary tract 647V 10.7
Urinary tract BC3C 9.9
Urinary tract BFTC905 10.4
Urinary tract CAL29 9.1
Urinary tract HS172T 9
Urinary tract HT1197 9.5
Urinary tract HT1376 9.7
Urinary tract J82 9.6
Urinary tract JMSU1 10.3
Urinary tract KMBC2 10.5
Urinary tract KU1919 10.3
Urinary tract RT11284 9.5
Urinary tract RT112 9.7
Urinary tract RT4 9.7
Urinary tract SCABER 9.9
Urinary tract SW1710 8.7
Urinary tract SW780 9.9
Urinary tract T24 9.8
Urinary tract TCCSUP 8.7
Urinary tract UMUC1 9.6
Urinary tract UMUC3 9.5
Urinary tract VMCUB1 10.1
> The Human Protein Atlas (HPA)
 


Tissue Expression Level (TPM)
Adipose tissue 21.7
Adrenal gland 46.2
Appendix 41.5
Bone marrow 75.7
Breast 24.8
Cerebral cortex 41.6
Cervix, uterine 50.5
Colon 29
Duodenum 22.4
Endometrium 58.6
Epididymis 33.1
Esophagus 37.5
Fallopian tube 52.8
Gallbladder 33.3
Heart muscle 14.2
Kidney 16.9
Liver 12.8
Lung 38.4
Lymph node 37.4
Ovary 49.4
Pancreas 14.8
Parathyroid gland 44.1
Placenta 37.5
Prostate 34.3
Rectum 23.9
Salivary gland 10.5
Seminal vesicle 33.5
Skeletal muscle 8
Skin 12.6
Small intestine 21.6
Smooth muscle 25.5
Spleen 35
Stomach 32.3
Testis 98.1
Thyroid gland 101.5
Tonsil 32.7
Urinary bladder 33.7
> Text Mining based Expression
 
PMID Expression Cancer Evidence
27388964overexpressionGlioblastomaBRD2 and BRD4, members of the BET family, are significantly increased in glioblastoma multiforme (GBM), the most common primary adult brain cancer.
26791111overexpressionHepatocellular CarcinomaFSH and LH levels were significantly increased in the HCC group when compared to controls.
Summary
SymbolBRD2
Namebromodomain containing 2
Aliases KIAA9001; RING3; D6S113E; NAT; FSRG1; bromodomain-containing 2; FSH; O27.1.1; female sterile homeotic-relate ......
Location6p21.32
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Somatic copy number alteration in primary tomur tissue
> The Cancer Genome Atlas (TCGA)
 


  Correlation between expression and SCNA as well as percentage of patients in different status.
Cancer Full Name # Sample R P % Loss % Neutral % Gain Status
BLCABladder urothelial carcinoma4040.4637.39e-2320.355.724Neutral
BRCABreast invasive carcinoma10750.4627.1e-581461.624.4Neutral
CESCCervical and endocervical cancers2920.4441.44e-151263.424.7Neutral
COADColon adenocarcinoma4490.4044.97e-199.669.920.5Neutral
ESCAEsophageal carcinoma1830.591.55e-1821.350.827.9Neutral
GBMGlioblastoma multiforme1470.493.09e-1017.778.24.1Neutral
HNSCHead and Neck squamous cell carcinoma5140.4012.78e-211666.317.7Neutral
KIRCKidney renal clear cell carcinoma5250.4483.14e-2718.779.61.7Neutral
KIRPKidney renal papillary cell carcinoma2880.3432.36e-099.788.91.4Neutral
LAMLAcute Myeloid Leukemia1660.0880.26201000Neutral
LGGBrain Lower Grade Glioma5130.3172.02e-135.592.81.8Neutral
LIHCLiver hepatocellular carcinoma3640.6258.15e-41357.139.8Gain
LUADLung adenocarcinoma5120.5582.92e-4311.551.437.1Gain
LUSCLung squamous cell carcinoma4980.4324.37e-2424.751.423.9Neutral
OVOvarian serous cystadenocarcinoma3000.7111.58e-4721.33444.7Gain
PAADPancreatic adenocarcinoma1770.5445.36e-1531.162.16.8Neutral
PCPGPheochromocytoma and Paraganglioma1620.2790.0003171.290.18.6Neutral
PRADProstate adenocarcinoma4910.1010.02534.791.63.7Neutral
READRectum adenocarcinoma1640.4143.43e-089.862.827.4Neutral
SARCSarcoma2550.4944.6e-1727.151.821.2Neutral
SKCMSkin Cutaneous Melanoma3670.7036.25e-568.440.950.7Gain
STADStomach adenocarcinoma4130.4991.92e-2712.864.922.3Neutral
TGCTTesticular Germ Cell Tumors1500.2970.000221107218Neutral
THCAThyroid carcinoma4970.0960.03320.898.80.4Neutral
THYMThymoma1190.5431.74e-1016.883.20Neutral
UCECUterine Corpus Endometrial Carcinoma5370.3842.81e-202.878.418.8Neutral
Summary
SymbolBRD2
Namebromodomain containing 2
Aliases KIAA9001; RING3; D6S113E; NAT; FSRG1; bromodomain-containing 2; FSH; O27.1.1; female sterile homeotic-relate ......
Location6p21.32
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Methylation level in the promoter region of CR
> Methylation level in the promoter region of CR
 


  Correlation between expression and methylation as well as differential methylation analysis.
Cancer Full Name R P # N # T Delta beta (T vs N) P value (T vs N) Status
BLCABladder urothelial carcinoma-0.2596.83e-08174080.0020.293NS/NA
BRCABreast invasive carcinoma-0.2051.28e-09837850.0010.0956NS/NA
CESCCervical and endocervical cancers-0.3064.81e-083306NANANS/NA
COADColon adenocarcinoma-0.1720.00218192970.0010.206NS/NA
ESCAEsophageal carcinoma-0.3391.53e-069185NANANS/NA
GBMGlioblastoma multiforme-0.5091.98e-05164NANANS/NA
HNSCHead and Neck squamous cell carcinoma-0.2334.46e-08205220.0040.503NS/NA
KIRCKidney renal clear cell carcinoma-0.1530.00461243190.0030.000105NS/NA
KIRPKidney renal papillary cell carcinoma-0.3631.39e-10232750.0173.93e-12NS/NA
LAMLAcute Myeloid Leukemia-0.1840.01640170NANANS/NA
LGGBrain Lower Grade Glioma-0.1180.00640530NANANS/NA
LIHCLiver hepatocellular carcinoma-0.292.04e-0941373-0.0020.764NS/NA
LUADLung adenocarcinoma-0.170.000198214560.0090.269NS/NA
LUSCLung squamous cell carcinoma-0.2955.84e-098370NANANS/NA
OVOvarian serous cystadenocarcinoma-0.8170.010809NANANS/NA
PAADPancreatic adenocarcinoma-0.3791.53e-074179NANANS/NA
PCPGPheochromocytoma and Paraganglioma-0.2190.002683184NANANS/NA
PRADProstate adenocarcinoma-0.1490.000551354980.0520.00919NS/NA
READRectum adenocarcinoma-0.4621.5e-06299NANANS/NA
SARCSarcoma-0.3898.44e-110263NANANS/NA
SKCMSkin Cutaneous Melanoma-0.47401471NANANS/NA
STADStomach adenocarcinoma-0.2298.97e-060372NANANS/NA
TGCTTesticular Germ Cell Tumors-0.3575.63e-060156NANANS/NA
THCAThyroid carcinoma-0.1160.0060650509-0.0020.556NS/NA
THYMThymoma-0.30.0008192120NANANS/NA
UCECUterine Corpus Endometrial Carcinoma-0.1875.14e-0534431-0.0090.519NS/NA
Summary
SymbolBRD2
Namebromodomain containing 2
Aliases KIAA9001; RING3; D6S113E; NAT; FSRG1; bromodomain-containing 2; FSH; O27.1.1; female sterile homeotic-relate ......
Location6p21.32
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Primary tumor tissue from TCGA
> Normal tumor tissue from HPA
>The Cancer Genome Atlas (TCGA)
 
There is no record.
> The Human Protein Atlas (HPA)
 


Tissue Level Level Name
Adrenal gland 1 Low
Appendix 1 Low
Bone marrow 0 Not detected
Breast 2 Medium
Bronchus 1 Low
Caudate 0 Not detected
Cerebellum 0 Not detected
Cerebral cortex 1 Low
Cervix, uterine 0 Not detected
Colon 2 Medium
Duodenum 1 Low
Endometrium 1 Low
Epididymis 2 Medium
Esophagus 1 Low
Fallopian tube 1 Low
Gallbladder 2 Medium
Heart muscle 1 Low
Hippocampus 0 Not detected
Kidney 1 Low
Liver 0 Not detected
Lung 1 Low
Lymph node 2 Medium
Nasopharynx 0 Not detected
Oral mucosa 1 Low
Ovary 0 Not detected
Pancreas 1 Low
Parathyroid gland 0 Not detected
Placenta 2 Medium
Prostate 0 Not detected
Rectum 2 Medium
Salivary gland 0 Not detected
Seminal vesicle 1 Low
Skeletal muscle 2 Medium
Skin 0 Not detected
Small intestine 1 Low
Smooth muscle 2 Medium
Soft tissue 0 Not detected
Spleen 0 Not detected
Stomach 1 Low
Testis 3 High
Thyroid gland 1 Low
Tonsil 2 Medium
Urinary bladder 1 Low
Vagina 0 Not detected
Summary
SymbolBRD2
Namebromodomain containing 2
Aliases KIAA9001; RING3; D6S113E; NAT; FSRG1; bromodomain-containing 2; FSH; O27.1.1; female sterile homeotic-relate ......
Location6p21.32
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Association between expresson and subtype
> Overall survival analysis based on expression
> Association between expresson and stage
> Association between expresson and grade
> Subtype
 


  Association between expresson and subtype.
Cancer Full Name # Patients P Value (Kruskal-Wallis) Association Source
BLCABladder urothelial carcinoma1280.156NS24476821
BRCABreast invasive carcinoma5215.03e-07Significant23000897
COADColon adenocarcinoma1490.379NS22810696
GBMGlioblastoma multiforme1570.00258Significant26824661
HNSCHead and Neck squamous cell carcinoma2790.00366Significant25631445
KIRPKidney renal papillary cell carcinoma1610.639NS26536169
LGGBrain Lower Grade Glioma5132.83e-12Significant26824661
LUADLung adenocarcinoma2300.000432Significant25079552
LUSCLung squamous cell carcinoma1780.129NS22960745
OVOvarian serous cystadenocarcinoma2870.00191Significant21720365
PRADProstate adenocarcinoma3335.98e-08Significant26544944
READRectum adenocarcinoma670.96NS22810696
SKCMSkin Cutaneous Melanoma3153.81e-05Significant26091043
STADStomach adenocarcinoma2779.01e-07Significant25079317
THCAThyroid carcinoma3912.9e-12Significant25417114
UCECUterine Corpus Endometrial Carcinoma2320.00278Significant23636398
> Overall survival
 

  Overall survival analysis based on expression.
Cancer Full Name # Patients Hazard Ratio P Value (Log Rank Test) Association
BLCABladder urothelial carcinoma405 0.6980.0945NS
BRCABreast invasive carcinoma1079 1.4660.112NS
CESCCervical and endocervical cancers291 1.2180.583NS
COADColon adenocarcinoma439 1.7590.0742NS
ESCAEsophageal carcinoma184 1.0540.87NS
GBMGlioblastoma multiforme158 0.870.59NS
HNSCHead and Neck squamous cell carcinoma518 0.8470.4NS
KIRCKidney renal clear cell carcinoma531 0.6290.0425Longer
KIRPKidney renal papillary cell carcinoma287 1.170.703NS
LAMLAcute Myeloid Leukemia149 0.950.855NS
LGGBrain Lower Grade Glioma511 0.5880.038Longer
LIHCLiver hepatocellular carcinoma365 0.8990.655NS
LUADLung adenocarcinoma502 0.9990.997NS
LUSCLung squamous cell carcinoma494 0.9770.904NS
OVOvarian serous cystadenocarcinoma303 0.6340.0356Longer
PAADPancreatic adenocarcinoma177 0.9170.772NS
PCPGPheochromocytoma and Paraganglioma179 2.9860.32NS
PRADProstate adenocarcinoma497 1.8660.543NS
READRectum adenocarcinoma159 0.4320.129NS
SARCSarcoma259 1.7140.0483Shorter
SKCMSkin Cutaneous Melanoma459 1.2170.288NS
STADStomach adenocarcinoma388 0.6350.0478Longer
TGCTTesticular Germ Cell Tumors134 0.6110.688NS
THCAThyroid carcinoma500 1.5020.502NS
THYMThymoma119 0.4320.302NS
UCECUterine Corpus Endometrial Carcinoma543 1.730.0712NS
> Stage
 

  Association between expresson and stage.
Cancer Full Name # Patients R Value (Spearman) P Value (Spearman) Association
BLCABladder urothelial carcinoma406 -0.1250.012Lower
BRCABreast invasive carcinoma1071 0.050.105NS
CESCCervical and endocervical cancers167 0.0670.392NS
COADColon adenocarcinoma445 0.0820.0837NS
ESCAEsophageal carcinoma162 -0.0760.336NS
HNSCHead and Neck squamous cell carcinoma448 -0.0470.316NS
KIRCKidney renal clear cell carcinoma531 -0.1470.000694Lower
KIRPKidney renal papillary cell carcinoma260 0.0270.666NS
LIHCLiver hepatocellular carcinoma347 -0.0220.679NS
LUADLung adenocarcinoma507 0.050.259NS
LUSCLung squamous cell carcinoma497 -0.0470.295NS
OVOvarian serous cystadenocarcinoma302 -0.090.117NS
PAADPancreatic adenocarcinoma176 -0.0780.303NS
READRectum adenocarcinoma156 0.1420.0767NS
SKCMSkin Cutaneous Melanoma410 -0.0070.892NS
STADStomach adenocarcinoma392 00.998NS
TGCTTesticular Germ Cell Tumors81 -0.1030.36NS
THCAThyroid carcinoma499 -0.1140.0105Lower
UCECUterine Corpus Endometrial Carcinoma501 0.0380.397NS
> Grade
 

  Association between expresson and grade.
Cancer Full Name # Patients R Value (Spearman) P Value (Spearman) Association
CESCCervical and endocervical cancers272 -0.0460.449NS
HNSCHead and Neck squamous cell carcinoma498 0.0150.741NS
KIRCKidney renal clear cell carcinoma525 -0.2373.69e-08Lower
LGGBrain Lower Grade Glioma514 0.0550.212NS
LIHCLiver hepatocellular carcinoma366 -0.0560.282NS
OVOvarian serous cystadenocarcinoma296 0.0220.701NS
PAADPancreatic adenocarcinoma176 -0.1350.0742NS
STADStomach adenocarcinoma406 -0.0230.643NS
UCECUterine Corpus Endometrial Carcinoma534 0.2786.72e-11Higher
Summary
SymbolBRD2
Namebromodomain containing 2
Aliases KIAA9001; RING3; D6S113E; NAT; FSRG1; bromodomain-containing 2; FSH; O27.1.1; female sterile homeotic-relate ......
Location6p21.32
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Targets inferred by reverse engineering method
> Targets identified by ChIP-seq data
> Targets inferred by reverse engineering method
 
> Targets identified by ChIP-seq data
 
Summary
SymbolBRD2
Namebromodomain containing 2
Aliases KIAA9001; RING3; D6S113E; NAT; FSRG1; bromodomain-containing 2; FSH; O27.1.1; female sterile homeotic-relate ......
Location6p21.32
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Drugs from DrugBank database
> Drugs from DrugBank database
 
There is no record for BRD2.
Summary
SymbolBRD2
Namebromodomain containing 2
Aliases KIAA9001; RING3; D6S113E; NAT; FSRG1; bromodomain-containing 2; FSH; O27.1.1; female sterile homeotic-relate ......
Location6p21.32
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Protein-Protein Interaction Network
> miRNA Regulatory Relationship
> Interactions from Text Mining
> Protein-Protein Interaction Network
 
> miRNA Regulatory Relationship
 
> Interactions from Text Mining
 
There is no record for BRD2.