Browse ING3 in pancancer

Summary
SymbolING3
Nameinhibitor of growth family member 3
Aliases p47ING3; FLJ20089; Eaf4; MEAF4; Inhibitor of growth protein 3
Location7q31.31
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Domain, Function and Classification
> Gene Ontology
> KEGG and Reactome Pathway
> Domain, Function and Classification
 
Domain PF12998 Inhibitor of growth proteins N-terminal histone-binding
Function

Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.

Classification
Class Modification Substrate Product PubMed
Chromatin remodelling, Histone modification write cofactor #, Histone acetylation H2A, H4 # 12545155
> Gene Ontology
 
Biological Process GO:0006473 protein acetylation
GO:0006475 internal protein amino acid acetylation
GO:0016570 histone modification
GO:0016573 histone acetylation
GO:0018205 peptidyl-lysine modification
GO:0018393 internal peptidyl-lysine acetylation
GO:0018394 peptidyl-lysine acetylation
GO:0043543 protein acylation
GO:0043967 histone H4 acetylation
GO:0043968 histone H2A acetylation
Molecular Function GO:0004402 histone acetyltransferase activity
GO:0008080 N-acetyltransferase activity
GO:0016407 acetyltransferase activity
GO:0016410 N-acyltransferase activity
GO:0016746 transferase activity, transferring acyl groups
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
GO:0034212 peptide N-acetyltransferase activity
GO:0035064 methylated histone binding
GO:0042393 histone binding
GO:0061733 peptide-lysine-N-acetyltransferase activity
Cellular Component GO:0000123 histone acetyltransferase complex
GO:0000785 chromatin
GO:0000790 nuclear chromatin
GO:0000812 Swr1 complex
GO:0031248 protein acetyltransferase complex
GO:0032777 Piccolo NuA4 histone acetyltransferase complex
GO:0035267 NuA4 histone acetyltransferase complex
GO:0043189 H4/H2A histone acetyltransferase complex
GO:0044454 nuclear chromosome part
GO:0070603 SWI/SNF superfamily-type complex
GO:0097346 INO80-type complex
GO:1902493 acetyltransferase complex
GO:1902562 H4 histone acetyltransferase complex
> KEGG and Reactome Pathway
 
KEGG -
Reactome R-HSA-3247509: Chromatin modifying enzymes
R-HSA-4839726: Chromatin organization
R-HSA-3214847: HATs acetylate histones
Summary
SymbolING3
Nameinhibitor of growth family member 3
Aliases p47ING3; FLJ20089; Eaf4; MEAF4; Inhibitor of growth protein 3
Location7q31.31
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Mutation landscape in primary tumor tissue from TCGA
> Mutation landscape in cancer cell line from CCLE
> All mutations from COSMIC database V81
> Variations from text mining
> The Cancer Genome Atlas (TCGA)
 
> Cancer Cell Line Encyclopedia (CCLE)
 
There is no record.
> Catalogue of Somatic Mutations in Cancer (COSMIC)
 
COSMIC ID CDS change AA change Mutation Type Anatomical Site
COSM3995306c.209A>Gp.Y70CSubstitution - MissenseKidney
COSM1312605c.966A>Tp.L322FSubstitution - MissenseUrinary_tract
COSM1635076c.557-2A>Tp.?UnknownLiver
COSM1666235c.967T>Ap.S323TSubstitution - MissenseEye
COSM3922569c.872C>Tp.S291LSubstitution - MissenseSkin
COSM3877553c.138C>Ap.F46LSubstitution - MissenseStomach
COSM1084551c.872C>Ap.S291*Substitution - NonsenseEndometrium
COSM6012873c.427C>Tp.P143SSubstitution - MissenseSkin
COSM4760691c.364C>Tp.R122*Substitution - NonsenseStomach
COSM4927839c.477T>Cp.D159DSubstitution - coding silentLiver
COSM1084552c.1027C>Tp.P343SSubstitution - MissenseEndometrium
COSM1447555c.706A>Gp.T236ASubstitution - MissenseLarge_intestine
COSM5776403c.288G>Cp.K96NSubstitution - MissenseBreast
COSM3632395c.896G>Tp.G299VSubstitution - MissenseSkin
COSM5710325c.1081C>Tp.R361*Substitution - NonsenseHaematopoietic_and_lymphoid_tissue
COSM5552766c.373G>Tp.E125*Substitution - NonsenseProstate
COSM5006371c.890G>Ap.R297QSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM1732978c.677C>Ap.T226NSubstitution - MissensePancreas
COSM5095977c.639T>Cp.I213ISubstitution - coding silentLarge_intestine
COSM1084549c.728G>Ap.R243QSubstitution - MissenseEndometrium
COSM744881c.118G>Cp.E40QSubstitution - MissenseLung
COSM1084548c.630_641del12p.Y211_G214delYNIGDeletion - In frameEndometrium
COSM1730605c.44C>Tp.P15LSubstitution - MissenseLiver
COSM1084550c.739A>Cp.S247RSubstitution - MissenseEndometrium
COSM3257620c.271G>Ap.D91NSubstitution - MissenseLarge_intestine
COSM4655997c.1051G>Ap.V351ISubstitution - MissenseLarge_intestine
COSM404627c.243G>Tp.Q81HSubstitution - MissenseLung
COSM275569c.563G>Ap.R188QSubstitution - MissenseLarge_intestine
COSM5884467c.138C>Gp.F46LSubstitution - MissenseLarge_intestine
COSM4422880c.34G>Cp.E12QSubstitution - MissenseKidney
COSM3632394c.10C>Tp.L4LSubstitution - coding silentSkin
COSM744879c.593A>Gp.N198SSubstitution - MissenseLung
COSM1622254c.557-4A>Gp.?UnknownLiver
COSM5997662c.1242C>Tp.G414GSubstitution - coding silentProstate
COSM275569c.563G>Ap.R188QSubstitution - MissenseBreast
COSM5062140c.679A>Gp.M227VSubstitution - MissenseStomach
COSM5824418c.138C>Tp.F46FSubstitution - coding silentLiver
COSM5696258c.464A>Gp.H155RSubstitution - MissenseSoft_tissue
COSM4692496c.171G>Ap.W57*Substitution - NonsenseLarge_intestine
COSM4155387c.424A>Tp.T142SSubstitution - MissenseKidney
COSM1254833c.219G>Tp.L73FSubstitution - MissenseOesophagus
COSM5894435c.700C>Tp.Q234*Substitution - NonsenseSkin
COSM338371c.608A>Tp.N203ISubstitution - MissenseLung
COSM275569c.563G>Ap.R188QSubstitution - MissenseEndometrium
COSM5033190c.84G>Ap.M28ISubstitution - MissenseOesophagus
COSM3632396c.898C>Tp.R300*Substitution - NonsenseSkin
COSM3877554c.162A>Gp.K54KSubstitution - coding silentStomach
COSM3745498c.1048C>Gp.Q350ESubstitution - MissenseLiver
COSM5976188c.858A>Gp.T286TSubstitution - coding silentUpper_aerodigestive_tract
COSM5710324c.920A>Cp.K307TSubstitution - MissenseHaematopoietic_and_lymphoid_tissue
COSM5421615c.455C>Gp.T152SSubstitution - MissenseProstate
COSM4155386c.312T>Ap.F104LSubstitution - MissenseKidney
COSM744880c.368C>Ap.S123YSubstitution - MissenseLung
COSM1236446c.1124G>Tp.G375VSubstitution - MissenseAutonomic_ganglia
COSM1622254c.557-4A>Gp.?UnknownLiver
COSM3725811c.1046G>Tp.S349ISubstitution - MissenseLung
COSM744879c.593A>Gp.N198SSubstitution - MissenseLiver
COSM292021c.72A>Tp.E24DSubstitution - MissenseLarge_intestine
COSM5710323c.910_912delAACp.N306delNDeletion - In frameHaematopoietic_and_lymphoid_tissue
COSM378500c.475G>Tp.D159YSubstitution - MissenseLung
COSM1239134c.528G>Ap.T176TSubstitution - coding silentOesophagus
COSM3394495c.773A>Gp.N258SSubstitution - MissensePancreas
COSM1662276c.337G>Tp.A113SSubstitution - MissenseKidney
COSM4514102c.962C>Tp.S321FSubstitution - MissenseSkin
COSM1312604c.85G>Ap.D29NSubstitution - MissenseUrinary_tract
COSM3381778c.282G>Cp.L94FSubstitution - MissensePancreas
COSM3922568c.622C>Tp.L208LSubstitution - coding silentSkin
COSM421626c.1160A>Cp.H387PSubstitution - MissenseUrinary_tract
COSM1447554c.542A>Cp.K181TSubstitution - MissenseLarge_intestine
COSM5039783c.787G>Ap.G263RSubstitution - MissenseLiver
COSM3257619c.215_216insTp.L73fs*6Insertion - FrameshiftLarge_intestine
COSM4499181c.536C>Tp.A179VSubstitution - MissenseSkin
COSM5507798c.565_567delAATp.N191delNDeletion - In frameBiliary_tract
COSM1084547c.49G>Tp.D17YSubstitution - MissenseEndometrium
COSM5585477c.385C>Tp.P129SSubstitution - MissenseSkin
COSM5954530c.1170C>Tp.C390CSubstitution - coding silentUpper_aerodigestive_tract
COSM225605c.503C>Tp.S168FSubstitution - MissenseSkin
COSM1236445c.1154G>Tp.W385LSubstitution - MissenseAutonomic_ganglia
COSM71166c.809G>Cp.R270TSubstitution - MissenseOvary
COSM1254834c.96G>Tp.V32VSubstitution - coding silentOesophagus
COSM5919341c.389C>Tp.S130LSubstitution - MissenseSkin
COSM5039783c.787G>Ap.G263RSubstitution - MissenseSkin
COSM3632397c.947C>Tp.S316FSubstitution - MissenseSkin
COSM4635468c.720G>Ap.K240KSubstitution - coding silentLarge_intestine
> Text Mining based Variations
 
There is no record for ING3.
Summary
SymbolING3
Nameinhibitor of growth family member 3
Aliases p47ING3; FLJ20089; Eaf4; MEAF4; Inhibitor of growth protein 3
Location7q31.31
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Post-translational modification (PTM)
> Post-translational modification (PTM)
 
 Filter By:
Uniprot ID Position Amino Acid Description Upstream Enzyme Affected By Mutation Amino Acid Sequence Variant
Q9NXR8264KN6-acetyllysine-NoNone detected
Summary
SymbolING3
Nameinhibitor of growth family member 3
Aliases p47ING3; FLJ20089; Eaf4; MEAF4; Inhibitor of growth protein 3
Location7q31.31
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Expression analysis in primary tumor tissue from TCGA
> Expression level in cancer cell line from CCLE
> Expression level in human normal tissue from HPA
> Text mining based expression change
> The Cancer Genome Atlas (TCGA)
 


  Differential expression analysis for cancers with more than 10 normal samples
Cancer Full Name # N # T Median (N) Median (T) LogFC Adj. P Status
BLCABladder urothelial carcinoma194083.6093.204-0.3880.00527NS
BRCABreast invasive carcinoma11211004.043.3-0.7091.34e-35Under
CESCCervical and endocervical cancers33064.2413.47NANANA
COADColon adenocarcinoma414593.7393.62-0.1860.0278NS
ESCAEsophageal carcinoma111853.8373.181-0.5730.00319NS
GBMGlioblastoma multiforme51663.4324.615NANANA
HNSCHead and Neck squamous cell carcinoma445223.172.819-0.2830.00789NS
KIRCKidney renal clear cell carcinoma725343.7734.2070.3713.54e-08NS
KIRPKidney renal papillary cell carcinoma322913.563.259-0.3210.00478NS
LAMLAcute Myeloid Leukemia0173NA4.639NANANA
LGGBrain Lower Grade Glioma0530NA4.243NANANA
LIHCLiver hepatocellular carcinoma503732.432.212-0.2190.0225NS
LUADLung adenocarcinoma595174.0313.528-0.4731.34e-12NS
LUSCLung squamous cell carcinoma515013.8353.446-0.4127.96e-07NS
OVOvarian serous cystadenocarcinoma0307NA3.707NANANA
PAADPancreatic adenocarcinoma41793.5393.206NANANA
PCPGPheochromocytoma and Paraganglioma31843.2973.627NANANA
PRADProstate adenocarcinoma524983.4473.5680.1480.104NS
READRectum adenocarcinoma101673.8323.551-0.4590.053NS
SARCSarcoma22633.2433.428NANANA
SKCMSkin Cutaneous Melanoma14723.643.427NANANA
STADStomach adenocarcinoma354153.5213.364-0.1090.249NS
TGCTTesticular Germ Cell Tumors0156NA3.908NANANA
THCAThyroid carcinoma595094.373.609-0.7584.3e-33Under
THYMThymoma21204.4764.126NANANA
UCECUterine Corpus Endometrial Carcinoma355463.8833.15-0.7635.36e-11Under
> Cancer Cell Line Encyclopedia (CCLE)
 



Tissue Cell Line Expression Level (Microarray)
Autonomic ganglia CHP126 8.1
Autonomic ganglia CHP212 8.1
Autonomic ganglia IMR32 7.8
Autonomic ganglia KELLY 8.6
Autonomic ganglia KPNRTBM1 8.1
Autonomic ganglia KPNSI9S 7.5
Autonomic ganglia KPNYN 8
Autonomic ganglia MHHNB11 6.9
Autonomic ganglia NB1 7
Autonomic ganglia NH6 7.7
Autonomic ganglia SHSY5Y 7.3
Autonomic ganglia SIMA 7.3
Autonomic ganglia SKNAS 7.3
Autonomic ganglia SKNBE2 7.2
Autonomic ganglia SKNDZ 8.6
Autonomic ganglia SKNFI 6.9
Autonomic ganglia SKNSH 7.8
Biliary tract HUCCT1 8.2
Biliary tract HUH28 6.5
Biliary tract SNU1079 6.4
Biliary tract SNU1196 7.2
Biliary tract SNU245 7.6
Biliary tract SNU308 7.3
Biliary tract SNU478 7.6
Bone 143B 7.5
Bone A673 7.1
Bone CADOES1 7.4
Bone CAL78 7.4
Bone G292CLONEA141B1 8
Bone HOS 7.3
Bone HS706T 7.4
Bone HS737T 7.1
Bone HS819T 7
Bone HS821T 7.3
Bone HS822T 7.2
Bone HS863T 7.4
Bone HS870T 7.6
Bone HS888T 7
Bone MG63 7.2
Bone MHHES1 8
Bone OUMS27 7.5
Bone RDES 7.1
Bone SJSA1 8
Bone SKES1 8.2
Bone SKNMC 7.4
Bone SW1353 7.9
Bone T173 7.2
Bone TC71 7.5
Bone U2OS 7
Breast AU565 7.4
Breast BT20 7.9
Breast BT474 7.2
Breast BT483 6.4
Breast BT549 7.3
Breast CAL120 7
Breast CAL148 7.2
Breast CAL51 7.5
Breast CAL851 7.7
Breast CAMA1 8
Breast DU4475 7.2
Breast EFM192A 7.4
Breast EFM19 7
Breast EVSAT 8.4
Breast HCC1143 7
Breast HCC1187 7.7
Breast HCC1395 8.5
Breast HCC1419 7.3
Breast HCC1428 6.5
Breast HCC1500 7.5
Breast HCC1569 8.2
Breast HCC1599 7.3
Breast HCC1806 6.8
Breast HCC1937 6.7
Breast HCC1954 7.1
Breast HCC202 6.8
Breast HCC2157 6.9
Breast HCC2218 6.6
Breast HCC38 7.9
Breast HCC70 7.5
Breast HDQP1 7.4
Breast HMC18 7.3
Breast HS274T 7
Breast HS281T 7.1
Breast HS343T 7.2
Breast HS578T 6.5
Breast HS606T 6.9
Breast HS739T 6.8
Breast HS742T 6.7
Breast JIMT1 6.3
Breast KPL1 7.1
Breast MCF7 7.1
Breast MDAMB134VI 7.7
Breast MDAMB157 8.2
Breast MDAMB175VII 7.1
Breast MDAMB231 7.8
Breast MDAMB361 7.2
Breast MDAMB415 7.8
Breast MDAMB436 7.7
Breast MDAMB453 7.2
Breast MDAMB468 8
Breast SKBR3 8.5
Breast T47D 6.3
Breast UACC812 6.3
Breast UACC893 6.7
Breast YMB1 6.9
Breast ZR751 7.4
Breast ZR7530 5.7
Central nervous system 1321N1 7.8
Central nervous system 42MGBA 6.9
Central nervous system 8MGBA 7.2
Central nervous system A172 7.3
Central nervous system AM38 7.7
Central nervous system BECKER 8.1
Central nervous system CAS1 7.2
Central nervous system CCFSTTG1 8
Central nervous system D283MED 6.1
Central nervous system D341MED 7.6
Central nervous system DAOY 7.9
Central nervous system DBTRG05MG 7.4
Central nervous system DKMG 8.1
Central nervous system GAMG 7.6
Central nervous system GB1 7.8
Central nervous system GI1 8
Central nervous system GMS10 7.2
Central nervous system GOS3 8.4
Central nervous system H4 7.1
Central nervous system HS683 8.3
Central nervous system KALS1 7.4
Central nervous system KG1C 7.6
Central nervous system KNS42 8.4
Central nervous system KNS60 7.1
Central nervous system KNS81 8.3
Central nervous system KS1 7.8
Central nervous system LN18 7.9
Central nervous system LN229 8.2
Central nervous system M059K 7.5
Central nervous system MOGGCCM 7.9
Central nervous system MOGGUVW 7.3
Central nervous system NMCG1 8.1
Central nervous system ONS76 7.6
Central nervous system SF126 7.4
Central nervous system SF295 7.9
Central nervous system SNB19 8.3
Central nervous system SNU1105 7.8
Central nervous system SNU201 7.5
Central nervous system SNU466 7.7
Central nervous system SNU489 7.2
Central nervous system SNU626 7.8
Central nervous system SNU738 7
Central nervous system SW1088 7.7
Central nervous system SW1783 7.9
Central nervous system T98G 7.3
Central nervous system TM31 6.8
Central nervous system U118MG 8.1
Central nervous system U138MG 7.9
Central nervous system U251MG 7.9
Central nervous system U87MG 7.1
Central nervous system YH13 7.5
Central nervous system YKG1 7.6
Endometrium AN3CA 7.2
Endometrium COLO684 6.9
Endometrium EFE184 7
Endometrium EN 6.7
Endometrium ESS1 7.6
Endometrium HEC108 6.8
Endometrium HEC151 7.4
Endometrium HEC1A 7.4
Endometrium HEC1B 7.9
Endometrium HEC251 7.9
Endometrium HEC265 7
Endometrium HEC50B 7.8
Endometrium HEC59 7.2
Endometrium HEC6 7.8
Endometrium ISHIKAWAHERAKLIO02ER 7.6
Endometrium JHUEM1 7.5
Endometrium JHUEM2 6.4
Endometrium JHUEM3 6.8
Endometrium KLE 7.2
Endometrium MFE280 7.1
Endometrium MFE296 7.2
Endometrium MFE319 7
Endometrium RL952 7
Endometrium SNGM 7.5
Endometrium SNU1077 6.3
Endometrium SNU685 6.9
Endometrium TEN 7.6
Haematopoietic and lymphoid 697 8.2
Haematopoietic and lymphoid A3KAW 8.1
Haematopoietic and lymphoid A4FUK 8.9
Haematopoietic and lymphoid ALLSIL 7.9
Haematopoietic and lymphoid AML193 8.3
Haematopoietic and lymphoid AMO1 8.6
Haematopoietic and lymphoid BCP1 8.1
Haematopoietic and lymphoid BDCM 8.1
Haematopoietic and lymphoid BL41 9.2
Haematopoietic and lymphoid BL70 9.6
Haematopoietic and lymphoid BV173 8.4
Haematopoietic and lymphoid CA46 8.8
Haematopoietic and lymphoid CI1 7.9
Haematopoietic and lymphoid CMK115 8.5
Haematopoietic and lymphoid CMK86 8.6
Haematopoietic and lymphoid CMK 8.1
Haematopoietic and lymphoid CMLT1 8.5
Haematopoietic and lymphoid COLO775 8
Haematopoietic and lymphoid DAUDI 8.7
Haematopoietic and lymphoid DB 8.3
Haematopoietic and lymphoid DEL 8.6
Haematopoietic and lymphoid DND41 7.5
Haematopoietic and lymphoid DOHH2 9.2
Haematopoietic and lymphoid EB1 8.3
Haematopoietic and lymphoid EB2 8.6
Haematopoietic and lymphoid EHEB 8
Haematopoietic and lymphoid EJM 8.6
Haematopoietic and lymphoid EM2 7.8
Haematopoietic and lymphoid EOL1 8.5
Haematopoietic and lymphoid F36P 8.6
Haematopoietic and lymphoid GA10 8.6
Haematopoietic and lymphoid GDM1 8.5
Haematopoietic and lymphoid GRANTA519 8.1
Haematopoietic and lymphoid HDLM2 7.4
Haematopoietic and lymphoid HDMYZ 7.5
Haematopoietic and lymphoid HEL9217 7.8
Haematopoietic and lymphoid HEL 7.7
Haematopoietic and lymphoid HH 8.1
Haematopoietic and lymphoid HL60 8.6
Haematopoietic and lymphoid HPBALL 8.2
Haematopoietic and lymphoid HS604T 7.1
Haematopoietic and lymphoid HS611T 8.1
Haematopoietic and lymphoid HS616T 7.2
Haematopoietic and lymphoid HS751T 7.3
Haematopoietic and lymphoid HT 8.7
Haematopoietic and lymphoid HTK 7.3
Haematopoietic and lymphoid HUNS1 7.6
Haematopoietic and lymphoid HUT102 8.5
Haematopoietic and lymphoid HUT78 7.9
Haematopoietic and lymphoid JEKO1 7.2
Haematopoietic and lymphoid JK1 8.4
Haematopoietic and lymphoid JM1 8.6
Haematopoietic and lymphoid JURKAT 7.5
Haematopoietic and lymphoid JURLMK1 8.1
Haematopoietic and lymphoid JVM2 8.4
Haematopoietic and lymphoid JVM3 7.4
Haematopoietic and lymphoid K562 9.1
Haematopoietic and lymphoid KARPAS299 7.9
Haematopoietic and lymphoid KARPAS422 7.6
Haematopoietic and lymphoid KARPAS620 8.6
Haematopoietic and lymphoid KASUMI1 7.7
Haematopoietic and lymphoid KASUMI2 8.9
Haematopoietic and lymphoid KASUMI6 7.4
Haematopoietic and lymphoid KCL22 7.5
Haematopoietic and lymphoid KE37 8.6
Haematopoietic and lymphoid KE97 7.7
Haematopoietic and lymphoid KG1 8.2
Haematopoietic and lymphoid KHM1B 8.7
Haematopoietic and lymphoid KIJK 8.8
Haematopoietic and lymphoid KMH2 7
Haematopoietic and lymphoid KMM1 8.6
Haematopoietic and lymphoid KMS11 8.7
Haematopoietic and lymphoid KMS12BM 8.3
Haematopoietic and lymphoid KMS18 8.1
Haematopoietic and lymphoid KMS20 7.4
Haematopoietic and lymphoid KMS21BM 8
Haematopoietic and lymphoid KMS26 8.3
Haematopoietic and lymphoid KMS27 8.1
Haematopoietic and lymphoid KMS28BM 8.6
Haematopoietic and lymphoid KMS34 8.9
Haematopoietic and lymphoid KO52 7.4
Haematopoietic and lymphoid KOPN8 7.2
Haematopoietic and lymphoid KU812 7.8
Haematopoietic and lymphoid KYO1 8.4
Haematopoietic and lymphoid L1236 7.9
Haematopoietic and lymphoid L363 8.8
Haematopoietic and lymphoid L428 8.4
Haematopoietic and lymphoid L540 9.2
Haematopoietic and lymphoid LAMA84 7.8
Haematopoietic and lymphoid LOUCY 8.2
Haematopoietic and lymphoid LP1 9
Haematopoietic and lymphoid M07E 8.7
Haematopoietic and lymphoid MC116 8.5
Haematopoietic and lymphoid ME1 7.1
Haematopoietic and lymphoid MEC1 8.4
Haematopoietic and lymphoid MEC2 8.1
Haematopoietic and lymphoid MEG01 7.7
Haematopoietic and lymphoid MHHCALL2 8.5
Haematopoietic and lymphoid MHHCALL3 8.5
Haematopoietic and lymphoid MHHCALL4 8.4
Haematopoietic and lymphoid MINO 8.7
Haematopoietic and lymphoid MJ 8.6
Haematopoietic and lymphoid MM1S 9.4
Haematopoietic and lymphoid MOLM13 8.2
Haematopoietic and lymphoid MOLM16 8.5
Haematopoietic and lymphoid MOLM6 7.3
Haematopoietic and lymphoid MOLP2 7.8
Haematopoietic and lymphoid MOLP8 8.2
Haematopoietic and lymphoid MOLT13 8.1
Haematopoietic and lymphoid MOLT16 8.7
Haematopoietic and lymphoid MOLT4 9
Haematopoietic and lymphoid MONOMAC1 7.6
Haematopoietic and lymphoid MONOMAC6 7.6
Haematopoietic and lymphoid MOTN1 8.4
Haematopoietic and lymphoid MUTZ5 8.3
Haematopoietic and lymphoid MV411 8.1
Haematopoietic and lymphoid NALM19 8.3
Haematopoietic and lymphoid NALM1 8.2
Haematopoietic and lymphoid NALM6 8.4
Haematopoietic and lymphoid NAMALWA 8.5
Haematopoietic and lymphoid NB4 8.6
Haematopoietic and lymphoid NCIH929 8.1
Haematopoietic and lymphoid NCO2 8.5
Haematopoietic and lymphoid NOMO1 6.7
Haematopoietic and lymphoid NUDHL1 7.5
Haematopoietic and lymphoid NUDUL1 8.3
Haematopoietic and lymphoid OCIAML2 8.4
Haematopoietic and lymphoid OCIAML3 8.4
Haematopoietic and lymphoid OCIAML5 8.1
Haematopoietic and lymphoid OCILY10 8
Haematopoietic and lymphoid OCILY19 8.3
Haematopoietic and lymphoid OCILY3 8.2
Haematopoietic and lymphoid OCIM1 8
Haematopoietic and lymphoid OPM2 8.3
Haematopoietic and lymphoid P12ICHIKAWA 7.7
Haematopoietic and lymphoid P31FUJ 8.2
Haematopoietic and lymphoid P3HR1 8.4
Haematopoietic and lymphoid PCM6 8.4
Haematopoietic and lymphoid PEER 9
Haematopoietic and lymphoid PF382 8.1
Haematopoietic and lymphoid PFEIFFER 7.8
Haematopoietic and lymphoid PL21 9.2
Haematopoietic and lymphoid RAJI 8.3
Haematopoietic and lymphoid RCHACV 8
Haematopoietic and lymphoid REC1 8.4
Haematopoietic and lymphoid REH 8.2
Haematopoietic and lymphoid RI1 8.4
Haematopoietic and lymphoid RL 8.7
Haematopoietic and lymphoid RPMI8226 8.5
Haematopoietic and lymphoid RPMI8402 8
Haematopoietic and lymphoid RS411 8.7
Haematopoietic and lymphoid SEM 8.5
Haematopoietic and lymphoid SET2 7
Haematopoietic and lymphoid SIGM5 7.9
Haematopoietic and lymphoid SKM1 7.7
Haematopoietic and lymphoid SKMM2 8.2
Haematopoietic and lymphoid SR786 7.8
Haematopoietic and lymphoid ST486 9.4
Haematopoietic and lymphoid SUDHL10 8.3
Haematopoietic and lymphoid SUDHL1 7.9
Haematopoietic and lymphoid SUDHL4 8.4
Haematopoietic and lymphoid SUDHL5 8.4
Haematopoietic and lymphoid SUDHL6 8.5
Haematopoietic and lymphoid SUDHL8 8.9
Haematopoietic and lymphoid SUPB15 8.7
Haematopoietic and lymphoid SUPHD1 7.6
Haematopoietic and lymphoid SUPM2 8.4
Haematopoietic and lymphoid SUPT11 6.8
Haematopoietic and lymphoid SUPT1 8.9
Haematopoietic and lymphoid TALL1 8.7
Haematopoietic and lymphoid TF1 8
Haematopoietic and lymphoid THP1 7.6
Haematopoietic and lymphoid TO175T 7.2
Haematopoietic and lymphoid TOLEDO 8.8
Haematopoietic and lymphoid U266B1 8.1
Haematopoietic and lymphoid U937 7.2
Haematopoietic and lymphoid UT7 7.7
Haematopoietic and lymphoid WSUDLCL2 8.2
Kidney 769P 7.9
Kidney 786O 7.9
Kidney A498 7.6
Kidney A704 8.8
Kidney ACHN 7.8
Kidney BFTC909 7
Kidney CAKI1 7.4
Kidney CAKI2 6.7
Kidney CAL54 7.8
Kidney KMRC1 7.3
Kidney KMRC20 8.9
Kidney KMRC2 7.5
Kidney KMRC3 6.7
Kidney OSRC2 6.8
Kidney RCC10RGB 6.8
Kidney SNU1272 6.7
Kidney SNU349 6.9
Kidney TUHR10TKB 7.5
Kidney TUHR14TKB 6.8
Kidney TUHR4TKB 7.3
Kidney VMRCRCW 7.1
Kidney VMRCRCZ 7.8
Large intestine C2BBE1 7.3
Large intestine CCK81 7
Large intestine CL11 7.4
Large intestine CL14 6.8
Large intestine CL34 7.4
Large intestine CL40 6.8
Large intestine COLO205 7.3
Large intestine COLO320 8.3
Large intestine COLO678 7
Large intestine CW2 7.2
Large intestine DLD1 7.3
Large intestine GP2D 6.9
Large intestine HCC56 7.6
Large intestine HCT116 7.2
Large intestine HCT15 7.9
Large intestine HS675T 7.3
Large intestine HS698T 7.3
Large intestine HT115 6.7
Large intestine HT29 7.9
Large intestine HT55 7.8
Large intestine KM12 8
Large intestine LOVO 8.4
Large intestine LS1034 8.2
Large intestine LS123 7.3
Large intestine LS180 6.8
Large intestine LS411N 8
Large intestine LS513 8.1
Large intestine MDST8 7.3
Large intestine NCIH508 7.7
Large intestine NCIH716 8.4
Large intestine NCIH747 7.7
Large intestine OUMS23 6.4
Large intestine RCM1 7.2
Large intestine RKO 8.4
Large intestine SKCO1 7.7
Large intestine SNU1040 6.5
Large intestine SNU1197 7.3
Large intestine SNU175 8.1
Large intestine SNU283 7.6
Large intestine SNU407 7
Large intestine SNU503 6.9
Large intestine SNU61 7.7
Large intestine SNU81 7.7
Large intestine SNUC1 7.6
Large intestine SNUC2A 7.9
Large intestine SNUC4 7.5
Large intestine SNUC5 7.7
Large intestine SW1116 7.5
Large intestine SW1417 8.5
Large intestine SW1463 7.2
Large intestine SW403 7.9
Large intestine SW480 7.7
Large intestine SW48 8.1
Large intestine SW620 8.2
Large intestine SW837 7.1
Large intestine SW948 7.6
Large intestine T84 6.7
Liver ALEXANDERCELLS 7.5
Liver C3A 6.5
Liver HEP3B217 7.8
Liver HEPG2 6.7
Liver HLE 7.2
Liver HLF 7.4
Liver HUH1 7
Liver HUH6 7.1
Liver HUH7 7.6
Liver JHH1 7.5
Liver JHH2 6.9
Liver JHH4 6.8
Liver JHH5 7.4
Liver JHH6 7.4
Liver JHH7 8
Liver LI7 7.2
Liver PLCPRF5 7.1
Liver SKHEP1 7.1
Liver SNU182 7.2
Liver SNU387 7.6
Liver SNU398 7.5
Liver SNU423 7.5
Liver SNU449 6.4
Liver SNU475 7.2
Liver SNU761 6.3
Liver SNU878 6.6
Liver SNU886 7.4
Lung A549 6.6
Lung ABC1 7.8
Lung BEN 7.1
Lung CAL12T 7
Lung CALU1 7.3
Lung CALU3 7
Lung CALU6 7.5
Lung CHAGOK1 8.2
Lung COLO668 8.4
Lung COLO699 8.5
Lung CORL105 7.3
Lung CORL23 7.3
Lung CORL24 8.8
Lung CORL279 7.5
Lung CORL311 7.9
Lung CORL47 8
Lung CORL51 7.9
Lung CORL88 7.9
Lung CORL95 8.3
Lung CPCN 8.8
Lung DMS114 6.9
Lung DMS153 8.4
Lung DMS273 7.8
Lung DMS454 8
Lung DMS53 8.5
Lung DMS79 7.3
Lung DV90 7.5
Lung EBC1 8.5
Lung EPLC272H 6.6
Lung HARA 7.7
Lung HCC1171 7.1
Lung HCC1195 6.8
Lung HCC15 7.5
Lung HCC2279 5.7
Lung HCC2935 8.5
Lung HCC33 7.5
Lung HCC366 7.6
Lung HCC4006 6.9
Lung HCC44 8.1
Lung HCC78 7.3
Lung HCC827 7.3
Lung HCC95 7.4
Lung HLC1 7.7
Lung HLFA 7.2
Lung HS229T 7.7
Lung HS618T 7.1
Lung IALM 7.6
Lung KNS62 6.7
Lung LC1F 6.8
Lung LC1SQSF 6.9
Lung LCLC103H 6.9
Lung LCLC97TM1 7.5
Lung LK2 8.7
Lung LOUNH91 7.8
Lung LU65 8.1
Lung LU99 6.3
Lung LUDLU1 7.6
Lung LXF289 6.9
Lung MORCPR 7.1
Lung NCIH1048 7.9
Lung NCIH1092 9
Lung NCIH1105 8.6
Lung NCIH1155 8.5
Lung NCIH1184 8.3
Lung NCIH1299 7.7
Lung NCIH1339 6.8
Lung NCIH1341 8.5
Lung NCIH1355 7
Lung NCIH1373 7.3
Lung NCIH1385 7.6
Lung NCIH1395 6.6
Lung NCIH1435 7.3
Lung NCIH1436 8.1
Lung NCIH1437 6
Lung NCIH146 8.4
Lung NCIH1563 6.2
Lung NCIH1568 6.8
Lung NCIH1573 6.5
Lung NCIH1581 8.2
Lung NCIH1618 8.2
Lung NCIH1623 7.1
Lung NCIH1648 7.5
Lung NCIH1650 6.3
Lung NCIH1651 7.3
Lung NCIH1666 7.3
Lung NCIH1693 7.9
Lung NCIH1694 7.9
Lung NCIH1703 7.1
Lung NCIH1734 8
Lung NCIH1755 7.4
Lung NCIH1781 7.8
Lung NCIH1792 7
Lung NCIH1793 7.1
Lung NCIH1836 8.7
Lung NCIH1838 7.9
Lung NCIH1869 7.9
Lung NCIH1876 8.1
Lung NCIH1915 7.4
Lung NCIH1930 8.4
Lung NCIH1944 7.7
Lung NCIH1963 7.9
Lung NCIH196 8
Lung NCIH1975 7.4
Lung NCIH2009 7.6
Lung NCIH2023 7.2
Lung NCIH2029 8.9
Lung NCIH2030 6.3
Lung NCIH2066 8.3
Lung NCIH2081 8.5
Lung NCIH2085 8
Lung NCIH2087 7.9
Lung NCIH209 7.2
Lung NCIH2106 7.9
Lung NCIH2110 7.4
Lung NCIH211 7.5
Lung NCIH2122 6.9
Lung NCIH2126 6.8
Lung NCIH2141 8.2
Lung NCIH2170 8.3
Lung NCIH2171 7.1
Lung NCIH2172 7
Lung NCIH2196 8.4
Lung NCIH2227 7.6
Lung NCIH2228 5.9
Lung NCIH226 7.4
Lung NCIH2286 7.8
Lung NCIH2291 7.6
Lung NCIH2342 6.5
Lung NCIH2347 8
Lung NCIH23 8.4
Lung NCIH2405 7.2
Lung NCIH2444 7.3
Lung NCIH292 7.3
Lung NCIH322 6.4
Lung NCIH3255 8.1
Lung NCIH358 7.3
Lung NCIH441 7.5
Lung NCIH446 7.8
Lung NCIH460 7.6
Lung NCIH510 7.6
Lung NCIH520 8.6
Lung NCIH522 8.6
Lung NCIH524 7.5
Lung NCIH526 8.1
Lung NCIH596 7
Lung NCIH647 7.3
Lung NCIH650 7.4
Lung NCIH661 8.1
Lung NCIH69 8.8
Lung NCIH727 7.5
Lung NCIH810 7.9
Lung NCIH82 8.1
Lung NCIH838 7.7
Lung NCIH841 7.3
Lung NCIH854 7
Lung NCIH889 8.9
Lung PC14 7.8
Lung RERFLCAD1 7.5
Lung RERFLCAD2 6.1
Lung RERFLCAI 8.1
Lung RERFLCKJ 6.7
Lung RERFLCMS 7.3
Lung RERFLCSQ1 6.3
Lung SBC5 7.7
Lung SCLC21H 8.5
Lung SHP77 7.8
Lung SKLU1 7.8
Lung SKMES1 6.7
Lung SQ1 7.2
Lung SW1271 8.2
Lung SW1573 7
Lung SW900 7.3
Lung VMRCLCD 8
Lung VMRCLCP 6.2
Oesophagus COLO680N 5.8
Oesophagus ECGI10 6.5
Oesophagus KYSE140 8.1
Oesophagus KYSE150 7.8
Oesophagus KYSE180 7.2
Oesophagus KYSE270 6.4
Oesophagus KYSE30 7.2
Oesophagus KYSE410 7.8
Oesophagus KYSE450 8.8
Oesophagus KYSE510 7
Oesophagus KYSE520 6.8
Oesophagus KYSE70 8.5
Oesophagus OE19 6.8
Oesophagus OE33 7.5
Oesophagus TE10 7
Oesophagus TE11 6.8
Oesophagus TE14 7.2
Oesophagus TE15 7.2
Oesophagus TE1 7.5
Oesophagus TE4 7.1
Oesophagus TE5 5.2
Oesophagus TE6 6.9
Oesophagus TE8 7
Oesophagus TE9 6.6
Oesophagus TT 6.7
Ovary 59M 5.3
Ovary A2780 7.5
Ovary CAOV3 7.4
Ovary CAOV4 7.4
Ovary COLO704 8.2
Ovary COV318 7.5
Ovary COV362 7.5
Ovary COV434 7.3
Ovary COV504 7.7
Ovary COV644 6.9
Ovary EFO21 7.4
Ovary EFO27 7.1
Ovary ES2 7.7
Ovary FUOV1 7
Ovary HEYA8 7.6
Ovary HS571T 6.8
Ovary IGROV1 7.2
Ovary JHOC5 6.7
Ovary JHOM1 6
Ovary JHOM2B 8
Ovary JHOS2 6.4
Ovary JHOS4 6.1
Ovary KURAMOCHI 8.4
Ovary MCAS 7.7
Ovary NIHOVCAR3 7.3
Ovary OAW28 7
Ovary OAW42 6.7
Ovary OC314 7.4
Ovary OC316 7.9
Ovary ONCODG1 7
Ovary OV56 6.2
Ovary OV7 6.6
Ovary OV90 7.7
Ovary OVCAR4 7.8
Ovary OVCAR8 6.4
Ovary OVISE 6.4
Ovary OVK18 7
Ovary OVKATE 7.8
Ovary OVMANA 6.3
Ovary OVSAHO 8.3
Ovary OVTOKO 7
Ovary RMGI 7.1
Ovary RMUGS 6.1
Ovary SKOV3 5.7
Ovary SNU119 6.9
Ovary SNU840 6.4
Ovary SNU8 7.5
Ovary TOV112D 6.8
Ovary TOV21G 7.1
Ovary TYKNU 8.5
Pancreas ASPC1 7
Pancreas BXPC3 7.4
Pancreas CAPAN1 6.7
Pancreas CAPAN2 7.7
Pancreas CFPAC1 7.1
Pancreas DANG 8.9
Pancreas HPAC 7.9
Pancreas HPAFII 6.2
Pancreas HS766T 7.8
Pancreas HUPT3 7.1
Pancreas HUPT4 8.1
Pancreas KCIMOH1 8
Pancreas KLM1 7
Pancreas KP2 7.8
Pancreas KP3 6.7
Pancreas KP4 7.6
Pancreas L33 6.2
Pancreas MIAPACA2 6.9
Pancreas PANC0203 7
Pancreas PANC0213 7.3
Pancreas PANC0327 8
Pancreas PANC0403 7.3
Pancreas PANC0504 7.7
Pancreas PANC0813 6.6
Pancreas PANC1005 7.6
Pancreas PANC1 7.5
Pancreas PATU8902 7.7
Pancreas PATU8988S 8
Pancreas PATU8988T 7.7
Pancreas PK1 7.4
Pancreas PK45H 7.8
Pancreas PK59 7.8
Pancreas PL45 8.2
Pancreas PSN1 6.5
Pancreas QGP1 8.5
Pancreas SNU213 6.7
Pancreas SNU324 8
Pancreas SNU410 7.3
Pancreas SU8686 6.2
Pancreas SUIT2 7.5
Pancreas SW1990 8
Pancreas T3M4 6.8
Pancreas TCCPAN2 6.9
Pancreas YAPC 7.6
Pleura ACCMESO1 7.4
Pleura DM3 6.3
Pleura ISTMES1 7
Pleura ISTMES2 7.6
Pleura JL1 6.7
Pleura MPP89 7
Pleura MSTO211H 7.7
Pleura NCIH2052 6.2
Pleura NCIH2452 6.9
Pleura NCIH28 7.9
Prostate 22RV1 8.5
Prostate DU145 7.3
Prostate LNCAPCLONEFGC 7.2
Prostate MDAPCA2B 8.8
Prostate NCIH660 8.1
Prostate PC3 7.5
Prostate VCAP 8.1
Salivary gland A253 7.4
Salivary gland YD15 7.6
Skin A101D 8.3
Skin A2058 7.7
Skin A375 8
Skin C32 9.2
Skin CHL1 7.4
Skin CJM 6.9
Skin COLO679 7.8
Skin COLO741 8.4
Skin COLO783 6.9
Skin COLO792 8.2
Skin COLO800 7.7
Skin COLO818 7.7
Skin COLO829 7.8
Skin COLO849 8.2
Skin G361 8.1
Skin GRM 7.5
Skin HMCB 8
Skin HS294T 7.7
Skin HS600T 7.2
Skin HS688AT 6.9
Skin HS695T 8.4
Skin HS839T 7.1
Skin HS852T 7
Skin HS895T 7.4
Skin HS934T 7.2
Skin HS936T 7.1
Skin HS939T 7.6
Skin HS940T 7.1
Skin HS944T 7.8
Skin HT144 7.7
Skin IGR1 7.3
Skin IGR37 7.7
Skin IGR39 7.9
Skin IPC298 7.3
Skin K029AX 7.6
Skin LOXIMVI 7.1
Skin MALME3M 7.8
Skin MDAMB435S 7.7
Skin MELHO 8.1
Skin MELJUSO 7.8
Skin MEWO 8
Skin RPMI7951 8
Skin RVH421 7.6
Skin SH4 8.1
Skin SKMEL1 8
Skin SKMEL24 7.7
Skin SKMEL28 6.7
Skin SKMEL2 7.4
Skin SKMEL30 7.3
Skin SKMEL31 8.1
Skin SKMEL3 7.9
Skin SKMEL5 8.1
Skin UACC257 7.4
Skin UACC62 6.7
Skin WM115 7.7
Skin WM1799 7.4
Skin WM2664 7.5
Skin WM793 8.3
Skin WM88 7.5
Skin WM983B 6.9
Small intestine HUTU80 7.7
Soft tissue A204 7
Soft tissue G401 7.4
Soft tissue G402 7.2
Soft tissue GCT 7.5
Soft tissue HS729 7.3
Soft tissue HT1080 8
Soft tissue KYM1 7.2
Soft tissue MESSA 5.9
Soft tissue RD 8.2
Soft tissue RH30 6.4
Soft tissue RH41 7.8
Soft tissue RKN 7.1
Soft tissue S117 6.8
Soft tissue SJRH30 8
Soft tissue SKLMS1 7.5
Soft tissue SKUT1 7.7
Soft tissue TE125T 7.6
Soft tissue TE159T 7
Soft tissue TE441T 8
Soft tissue TE617T 7.6
Stomach 2313287 7.7
Stomach AGS 7.8
Stomach AZ521 7.9
Stomach ECC10 8
Stomach ECC12 7.1
Stomach FU97 7
Stomach GCIY 7.4
Stomach GSS 7.7
Stomach GSU 7.4
Stomach HGC27 8.1
Stomach HS746T 7.4
Stomach HUG1N 7.9
Stomach IM95 7.8
Stomach KATOIII 7.8
Stomach KE39 8.1
Stomach LMSU 7.1
Stomach MKN1 7.7
Stomach MKN45 10.7
Stomach MKN74 7.6
Stomach MKN7 6.4
Stomach NCCSTCK140 6.6
Stomach NCIN87 6.8
Stomach NUGC2 6.2
Stomach NUGC3 6.9
Stomach NUGC4 7.5
Stomach OCUM1 7.4
Stomach RERFGC1B 7.6
Stomach SH10TC 6.6
Stomach SNU16 8.1
Stomach SNU1 8.5
Stomach SNU216 7.4
Stomach SNU520 8
Stomach SNU5 9.7
Stomach SNU601 7.1
Stomach SNU620 7.2
Stomach SNU668 7.3
Stomach SNU719 6.9
Stomach TGBC11TKB 7
Thyroid 8305C 6.7
Thyroid 8505C 7
Thyroid BCPAP 5.5
Thyroid BHT101 7.8
Thyroid CAL62 7.5
Thyroid CGTHW1 6.2
Thyroid FTC133 7.5
Thyroid FTC238 7.8
Thyroid ML1 7.1
Thyroid SW579 7.5
Thyroid TT2609C02 7.2
Thyroid TT 7.8
Upper aerodigestive tract BHY 6.9
Upper aerodigestive tract BICR16 5.4
Upper aerodigestive tract BICR18 7.1
Upper aerodigestive tract BICR22 6.7
Upper aerodigestive tract BICR31 6.7
Upper aerodigestive tract BICR56 6.5
Upper aerodigestive tract BICR6 6.6
Upper aerodigestive tract CAL27 7.4
Upper aerodigestive tract CAL33 6.6
Upper aerodigestive tract DETROIT562 7.2
Upper aerodigestive tract FADU 7.7
Upper aerodigestive tract HS840T 7.2
Upper aerodigestive tract HSC2 7.4
Upper aerodigestive tract HSC3 6.8
Upper aerodigestive tract HSC4 6.8
Upper aerodigestive tract PECAPJ15 6.6
Upper aerodigestive tract PECAPJ34CLONEC12 7.9
Upper aerodigestive tract PECAPJ41CLONED2 6.5
Upper aerodigestive tract PECAPJ49 6.5
Upper aerodigestive tract SCC15 6.7
Upper aerodigestive tract SCC25 6.5
Upper aerodigestive tract SCC4 6.4
Upper aerodigestive tract SCC9 6.5
Upper aerodigestive tract SNU1076 6.5
Upper aerodigestive tract SNU1214 6.6
Upper aerodigestive tract SNU46 7.2
Upper aerodigestive tract SNU899 7.7
Upper aerodigestive tract YD10B 6.5
Upper aerodigestive tract YD38 7.1
Upper aerodigestive tract YD8 6.8
Urinary tract 5637 7.8
Urinary tract 639V 7.2
Urinary tract 647V 7.7
Urinary tract BC3C 6.4
Urinary tract BFTC905 7.5
Urinary tract CAL29 6.5
Urinary tract HS172T 7.3
Urinary tract HT1197 6.7
Urinary tract HT1376 7.9
Urinary tract J82 7.5
Urinary tract JMSU1 7.7
Urinary tract KMBC2 8
Urinary tract KU1919 6.5
Urinary tract RT11284 7.8
Urinary tract RT112 7.3
Urinary tract RT4 8.2
Urinary tract SCABER 7.1
Urinary tract SW1710 7.2
Urinary tract SW780 7.1
Urinary tract T24 7.4
Urinary tract TCCSUP 6.3
Urinary tract UMUC1 7
Urinary tract UMUC3 7.7
Urinary tract VMCUB1 7.2
> The Human Protein Atlas (HPA)
 


Tissue Expression Level (TPM)
Adipose tissue 10.6
Adrenal gland 10.3
Appendix 13.5
Bone marrow 50.4
Breast 12.4
Cerebral cortex 12
Cervix, uterine 12.7
Colon 9.2
Duodenum 8.5
Endometrium 17.6
Epididymis 12.5
Esophagus 8.2
Fallopian tube 15.3
Gallbladder 13.5
Heart muscle 5.7
Kidney 10.2
Liver 4.7
Lung 16.3
Lymph node 17.6
Ovary 10.7
Pancreas 1.7
Parathyroid gland 13.2
Placenta 21.5
Prostate 12.2
Rectum 13.2
Salivary gland 3.4
Seminal vesicle 10.6
Skeletal muscle 1.6
Skin 5.5
Small intestine 8.3
Smooth muscle 18.6
Spleen 21.6
Stomach 8.9
Testis 15
Thyroid gland 19.2
Tonsil 12.7
Urinary bladder 11.5
> Text Mining based Expression
 
PMID Expression Cancer Evidence
28511652overexpressionProstate CarcinomaWe find that ING3 levels and AR activity positively correlate in prostate cancer.
28403887overexpressionProstate CarcinomaWe then ran a factorial discriminant analysis (FDA) and compared the enriched genes in prostate-tumor biopsies and normal biopsies using ANOVA to identify significantly differentially-enriched genes. The analysis identified ALG5, EXOSC8, CBX1, GRID2, GRIN3B, ING3, MYO1D, NPHP3-AS1, MSH6, FBXO11, SND1, SPATS2, TENM4 and TRA2A genes.
26803516UnderexpressionProstate CarcinomaING3 expression was highest in benign prostate tissues (mean 3.2±0.54) compared to PCa (mean 2.5±0.26) (p=0.437), advanced prostate cancer (AdvPCa) (mean 1.5±0.32) (p=0.004), and castration-resistant prostate cancer (CRPC) (mean 2.28±0.32) (p=0.285). Higher ING3 expression was marginally associated with lethal disease (p=0.052), and this was more pronounced in patients with ERG-negative status (p=0.018).
24927342UnderexpressionColorectal AdenocarcinomaCarcinomas showed significantly lower ING3 expression than matched NNM at mRNA level (P< 0.05), but not at protein level. Immunohistochemically, ING3 expression was significantly decreased from NNM, adenoma to adenocarcinoma (P< 0.05). Our study showed that downregulated ING3 expression might play an important role in colorectal adenoma-adenocarcinoma sequence.
22550337UnderexpressionHepatocellular CarcinomaBoth mRNA and protein concentrations of ING3 were found to be downregulated in the majority of HCC tumors in comparison with matched non-tumor hepatic tissues. Analysis of the relationship between ING3 staining and clinico-pathological characteristics of HCC showed that the low expression of ING3 protein is correlated with more aggressive behavior of the tumor.
18081876UnderexpressionHead and Neck CarcinomaAbout half of the 71 tumor samples demonstrated downregulation of ING3 compared to their matched normal counterparts.
17634537UnderexpressionHuman Cutaneous MelanomaNuclear ING3 expression was remarkably reduced in malignant melanomas compared with dysplastic nevi (P<0.001), which was significantly correlated with the increased ING3 level in cytoplasm (P<0.05).
12080476Underexpression; Loss of expressionHead and Neck Squamous Cell CarcinomaReverse-transcription-PCR analysis demonstrated decreased or no expression of ING3 mRNA in 50% of primary tumors as compared with that of matched normal samples. Especially, about 63% of tongue and larynx tumors showed the decrease and a tendency of higher mortality was observed in cases with decreased ING3 expression.
Summary
SymbolING3
Nameinhibitor of growth family member 3
Aliases p47ING3; FLJ20089; Eaf4; MEAF4; Inhibitor of growth protein 3
Location7q31.31
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Somatic copy number alteration in primary tomur tissue
> The Cancer Genome Atlas (TCGA)
 


  Correlation between expression and SCNA as well as percentage of patients in different status.
Cancer Full Name # Sample R P % Loss % Neutral % Gain Status
BLCABladder urothelial carcinoma4040.4134.4e-1810.655.234.2Gain
BRCABreast invasive carcinoma10750.3786.13e-3813.960.226Neutral
CESCCervical and endocervical cancers2920.3441.59e-0917.169.513.4Neutral
COADColon adenocarcinoma4490.2715.25e-091.149.749.2Gain
ESCAEsophageal carcinoma1830.5872.31e-1830.63534.4Gain
GBMGlioblastoma multiforme1470.391.06e-06017.782.3Gain
HNSCHead and Neck squamous cell carcinoma5140.4031.65e-2118.561.120.4Neutral
KIRCKidney renal clear cell carcinoma5250.261.49e-091.166.532.4Neutral
KIRPKidney renal papillary cell carcinoma2880.3943.78e-120.339.260.4Gain
LAMLAcute Myeloid Leukemia1660.545.92e-1411.4880.6Neutral
LGGBrain Lower Grade Glioma5130.4363.61e-25165.333.7Gain
LIHCLiver hepatocellular carcinoma3640.4085.03e-168.560.231.3Neutral
LUADLung adenocarcinoma5120.5024.31e-3411.747.540.8Gain
LUSCLung squamous cell carcinoma4980.5111.53e-3415.140.844.2Gain
OVOvarian serous cystadenocarcinoma3000.6993.1e-4515.742.741.7Gain
PAADPancreatic adenocarcinoma1770.321.42e-057.368.923.7Neutral
PCPGPheochromocytoma and Paraganglioma1620.4588.76e-105.682.112.3Neutral
PRADProstate adenocarcinoma4910.1998.75e-062.977.220Neutral
READRectum adenocarcinoma1640.3514.01e-06347.649.4Gain
SARCSarcoma2550.3965.37e-1114.557.627.8Neutral
SKCMSkin Cutaneous Melanoma3670.4261.41e-175.435.159.4Gain
STADStomach adenocarcinoma4130.5021.02e-2715.748.935.4Gain
TGCTTesticular Germ Cell Tumors1500.572.77e-145.328.766Gain
THCAThyroid carcinoma4970.1270.004710964Neutral
THYMThymoma119-0.0280.7662.583.214.3Neutral
UCECUterine Corpus Endometrial Carcinoma5370.3092.33e-1310.87613.2Neutral
Summary
SymbolING3
Nameinhibitor of growth family member 3
Aliases p47ING3; FLJ20089; Eaf4; MEAF4; Inhibitor of growth protein 3
Location7q31.31
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Methylation level in the promoter region of CR
> Methylation level in the promoter region of CR
 


  Correlation between expression and methylation as well as differential methylation analysis.
Cancer Full Name R P # N # T Delta beta (T vs N) P value (T vs N) Status
BLCABladder urothelial carcinoma-0.1850.00013117408-0.0020.375NS/NA
BRCABreast invasive carcinoma-0.1984.41e-09837850.0022.28e-07NS/NA
CESCCervical and endocervical cancers-0.2160.0001373306NANANS/NA
COADColon adenocarcinoma-0.1050.0619192970.0010.163NS/NA
ESCAEsophageal carcinoma-0.2992.43e-059185NANANS/NA
GBMGlioblastoma multiforme-0.3820.0018164NANANS/NA
HNSCHead and Neck squamous cell carcinoma-0.1983.52e-0620522-0.0240.182NS/NA
KIRCKidney renal clear cell carcinoma-0.0950.079124319-0.0040.11NS/NA
KIRPKidney renal papillary cell carcinoma-0.1290.0262327500.223NS/NA
LAMLAcute Myeloid Leukemia-0.190.01320170NANANS/NA
LGGBrain Lower Grade Glioma-0.1580.0002690530NANANS/NA
LIHCLiver hepatocellular carcinoma-0.2111.6e-05413730.0050.106NS/NA
LUADLung adenocarcinoma-0.0820.072321456-0.0170.0459NS/NA
LUSCLung squamous cell carcinoma-0.2142.84e-058370NANANS/NA
OVOvarian serous cystadenocarcinoma-0.750.025509NANANS/NA
PAADPancreatic adenocarcinoma-0.3315.42e-064179NANANS/NA
PCPGPheochromocytoma and Paraganglioma-0.1860.0113184NANANS/NA
PRADProstate adenocarcinoma-0.1520.00042735498-0.0050.0384NS/NA
READRectum adenocarcinoma-0.1650.0994299NANANS/NA
SARCSarcoma-0.2080.0007080263NANANS/NA
SKCMSkin Cutaneous Melanoma-0.2039.66e-061471NANANS/NA
STADStomach adenocarcinoma-0.1780.0005870372NANANS/NA
TGCTTesticular Germ Cell Tumors-0.0910.260156NANANS/NA
THCAThyroid carcinoma-0.0980.02065050900.495NS/NA
THYMThymoma-0.1630.07322120NANANS/NA
UCECUterine Corpus Endometrial Carcinoma-0.1640.000377344310.0110.0144NS/NA
Summary
SymbolING3
Nameinhibitor of growth family member 3
Aliases p47ING3; FLJ20089; Eaf4; MEAF4; Inhibitor of growth protein 3
Location7q31.31
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Primary tumor tissue from TCGA
> Normal tumor tissue from HPA
>The Cancer Genome Atlas (TCGA)
 
There is no record.
> The Human Protein Atlas (HPA)
 


Tissue Level Level Name
Adrenal gland 0 Not detected
Appendix 1 Low
Bone marrow 0 Not detected
Breast 0 Not detected
Bronchus 1 Low
Caudate 0 Not detected
Cerebellum 0 Not detected
Cerebral cortex 0 Not detected
Cervix, uterine 0 Not detected
Colon 0 Not detected
Duodenum 1 Low
Endometrium 1 Low
Epididymis 1 Low
Esophagus 0 Not detected
Fallopian tube 0 Not detected
Gallbladder 0 Not detected
Heart muscle 0 Not detected
Hippocampus 0 Not detected
Kidney 1 Low
Liver 0 Not detected
Lung 1 Low
Lymph node 1 Low
Nasopharynx 0 Not detected
Oral mucosa 0 Not detected
Ovary 0 Not detected
Pancreas 0 Not detected
Parathyroid gland 0 Not detected
Placenta 1 Low
Prostate 1 Low
Rectum 0 Not detected
Salivary gland 0 Not detected
Seminal vesicle 0 Not detected
Skeletal muscle 0 Not detected
Skin 1 Low
Small intestine 0 Not detected
Smooth muscle 0 Not detected
Soft tissue 0 Not detected
Spleen 0 Not detected
Stomach 1 Low
Testis 1 Low
Thyroid gland 0 Not detected
Tonsil 1 Low
Urinary bladder 0 Not detected
Vagina 0 Not detected
Summary
SymbolING3
Nameinhibitor of growth family member 3
Aliases p47ING3; FLJ20089; Eaf4; MEAF4; Inhibitor of growth protein 3
Location7q31.31
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Association between expresson and subtype
> Overall survival analysis based on expression
> Association between expresson and stage
> Association between expresson and grade
> Subtype
 


  Association between expresson and subtype.
Cancer Full Name # Patients P Value (Kruskal-Wallis) Association Source
BLCABladder urothelial carcinoma1280.252NS24476821
BRCABreast invasive carcinoma5212.46e-13Significant23000897
COADColon adenocarcinoma1490.669NS22810696
GBMGlioblastoma multiforme1574.22e-05Significant26824661
HNSCHead and Neck squamous cell carcinoma2797.47e-13Significant25631445
KIRPKidney renal papillary cell carcinoma1610.0356Significant26536169
LGGBrain Lower Grade Glioma5130.000106Significant26824661
LUADLung adenocarcinoma2300.419NS25079552
LUSCLung squamous cell carcinoma1780.00223Significant22960745
OVOvarian serous cystadenocarcinoma2870.249NS21720365
PRADProstate adenocarcinoma3331.24e-08Significant26544944
READRectum adenocarcinoma670.0476Significant22810696
SKCMSkin Cutaneous Melanoma3150.0114Significant26091043
STADStomach adenocarcinoma2774.8e-08Significant25079317
THCAThyroid carcinoma3911.53e-05Significant25417114
UCECUterine Corpus Endometrial Carcinoma2320.623NS23636398
> Overall survival
 

  Overall survival analysis based on expression.
Cancer Full Name # Patients Hazard Ratio P Value (Log Rank Test) Association
BLCABladder urothelial carcinoma405 0.7130.102NS
BRCABreast invasive carcinoma1079 1.0990.69NS
CESCCervical and endocervical cancers291 1.0970.792NS
COADColon adenocarcinoma439 0.8440.551NS
ESCAEsophageal carcinoma184 0.8220.541NS
GBMGlioblastoma multiforme158 0.9880.972NS
HNSCHead and Neck squamous cell carcinoma518 0.6770.0475Longer
KIRCKidney renal clear cell carcinoma531 0.4880.000592Longer
KIRPKidney renal papillary cell carcinoma287 0.8350.681NS
LAMLAcute Myeloid Leukemia149 0.6590.162NS
LGGBrain Lower Grade Glioma511 1.1320.613NS
LIHCLiver hepatocellular carcinoma365 0.7580.265NS
LUADLung adenocarcinoma502 0.6840.0629NS
LUSCLung squamous cell carcinoma494 0.950.799NS
OVOvarian serous cystadenocarcinoma303 0.9990.994NS
PAADPancreatic adenocarcinoma177 0.7130.28NS
PCPGPheochromocytoma and Paraganglioma179 0.3180.295NS
PRADProstate adenocarcinoma497 2.5860.3NS
READRectum adenocarcinoma159 0.6180.457NS
SARCSarcoma259 0.9250.786NS
SKCMSkin Cutaneous Melanoma459 0.770.162NS
STADStomach adenocarcinoma388 1.0160.939NS
TGCTTesticular Germ Cell Tumors134 946949227.0870.48NS
THCAThyroid carcinoma500 1.0180.979NS
THYMThymoma119 00.0215Longer
UCECUterine Corpus Endometrial Carcinoma543 1.2560.468NS
> Stage
 

  Association between expresson and stage.
Cancer Full Name # Patients R Value (Spearman) P Value (Spearman) Association
BLCABladder urothelial carcinoma406 -0.1640.000882Lower
BRCABreast invasive carcinoma1071 -0.0440.153NS
CESCCervical and endocervical cancers167 -0.0530.493NS
COADColon adenocarcinoma445 -0.0730.123NS
ESCAEsophageal carcinoma162 -0.010.899NS
HNSCHead and Neck squamous cell carcinoma448 -0.1080.0227Lower
KIRCKidney renal clear cell carcinoma531 -0.2051.9e-06Lower
KIRPKidney renal papillary cell carcinoma260 -0.0620.32NS
LIHCLiver hepatocellular carcinoma347 -0.0130.808NS
LUADLung adenocarcinoma507 -0.0280.527NS
LUSCLung squamous cell carcinoma497 -0.0330.469NS
OVOvarian serous cystadenocarcinoma302 0.0370.523NS
PAADPancreatic adenocarcinoma176 -0.1530.042Lower
READRectum adenocarcinoma156 0.0710.378NS
SKCMSkin Cutaneous Melanoma410 0.0410.402NS
STADStomach adenocarcinoma392 0.0010.985NS
TGCTTesticular Germ Cell Tumors81 0.3160.0041Higher
THCAThyroid carcinoma499 -0.1843.58e-05Lower
UCECUterine Corpus Endometrial Carcinoma501 0.0620.165NS
> Grade
 

  Association between expresson and grade.
Cancer Full Name # Patients R Value (Spearman) P Value (Spearman) Association
CESCCervical and endocervical cancers272 -0.0280.646NS
HNSCHead and Neck squamous cell carcinoma498 0.170.000136Higher
KIRCKidney renal clear cell carcinoma525 -0.2843.22e-11Lower
LGGBrain Lower Grade Glioma514 0.0710.106NS
LIHCLiver hepatocellular carcinoma366 -0.0160.765NS
OVOvarian serous cystadenocarcinoma296 0.0070.911NS
PAADPancreatic adenocarcinoma176 -0.1960.00902Lower
STADStomach adenocarcinoma406 -0.0350.481NS
UCECUterine Corpus Endometrial Carcinoma534 0.0740.0858NS
Summary
SymbolING3
Nameinhibitor of growth family member 3
Aliases p47ING3; FLJ20089; Eaf4; MEAF4; Inhibitor of growth protein 3
Location7q31.31
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Targets inferred by reverse engineering method
> Targets identified by ChIP-seq data
> Targets inferred by reverse engineering method
 
> Targets identified by ChIP-seq data
 
Summary
SymbolING3
Nameinhibitor of growth family member 3
Aliases p47ING3; FLJ20089; Eaf4; MEAF4; Inhibitor of growth protein 3
Location7q31.31
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Drugs from DrugBank database
> Drugs from DrugBank database
 
There is no record for ING3.
Summary
SymbolING3
Nameinhibitor of growth family member 3
Aliases p47ING3; FLJ20089; Eaf4; MEAF4; Inhibitor of growth protein 3
Location7q31.31
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content > Protein-Protein Interaction Network
> miRNA Regulatory Relationship
> Interactions from Text Mining
> Protein-Protein Interaction Network
 
> miRNA Regulatory Relationship
 
> Interactions from Text Mining
 
There is no record for ING3.