Browse MBD5 in pancancer

Summary
Symbol	MBD5
Name	methyl-CpG binding domain protein 5
Aliases	FLJ11113; KIAA1461; MRD1; methyl-CpG-binding protein MBD5; Methyl-CpG-binding domain protein 5
Location	2q23.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

Domain

PF00855 PWWP domain

Function

Binds to heterochromatin. Does not interact with either methylated or unmethylated DNA (in vitro).

Classification

Class	Modification	Substrate	Product	PubMed
Chromatin remodelling	#	#	#	20700456

> Gene Ontology [ TOP ]
Biological Process	GO:0033500 carbohydrate homeostasis GO:0035264 multicellular organism growth GO:0040014 regulation of multicellular organism growth GO:0042593 glucose homeostasis GO:0043434 response to peptide hormone GO:0044708 single-organism behavior GO:0048638 regulation of developmental growth GO:0060396 growth hormone receptor signaling pathway GO:0060398 regulation of growth hormone receptor signaling pathway GO:0060399 positive regulation of growth hormone receptor signaling pathway GO:0060416 response to growth hormone GO:0071375 cellular response to peptide hormone stimulus GO:0071378 cellular response to growth hormone stimulus GO:0071417 cellular response to organonitrogen compound GO:1901652 response to peptide GO:1901653 cellular response to peptide
Molecular Function	GO:0003682 chromatin binding
Cellular Component	GO:0010369 chromocenter GO:0098687 chromosomal region

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	R-HSA-5688426: Deubiquitination R-HSA-392499: Metabolism of proteins R-HSA-597592: Post-translational protein modification R-HSA-5689603: UCH proteinases

Summary
Symbol	MBD5
Name	methyl-CpG binding domain protein 5
Aliases	FLJ11113; KIAA1461; MRD1; methyl-CpG-binding protein MBD5; Methyl-CpG-binding domain protein 5
Location	2q23.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM4820629	c.3588G>A	p.Q1196Q	Substitution - coding silent	Cervix
COSM1243395	c.3620G>A	p.R1207Q	Substitution - Missense	Oesophagus
COSM4398601	c.3784G>A	p.E1262K	Substitution - Missense	Skin
COSM4136066	c.1260G>C	p.G420G	Substitution - coding silent	Ovary
COSM3296126	c.1276G>A	p.V426I	Substitution - Missense	Upper_aerodigestive_tract
COSM3296151	c.1828G>A	p.G610S	Substitution - Missense	Upper_aerodigestive_tract
COSM3296117	c.1120G>A	p.V374I	Substitution - Missense	Upper_aerodigestive_tract
COSM3894918	c.2460C>T	p.S820S	Substitution - coding silent	Skin
COSM475989	c.2340T>G	p.L780L	Substitution - coding silent	Kidney
COSM1399838	c.87G>T	p.V29V	Substitution - coding silent	Large_intestine
COSM3296124	c.1248C>T	p.H416H	Substitution - coding silent	Upper_aerodigestive_tract
COSM3567436	c.1221C>T	p.L407L	Substitution - coding silent	Skin
COSM3961264	c.1096A>G	p.S366G	Substitution - Missense	Lung
COSM1007225	c.1991C>T	p.T664M	Substitution - Missense	Endometrium
COSM3296201	c.3237C>T	p.G1079G	Substitution - coding silent	Stomach
COSM5632349	c.2213A>G	p.H738R	Substitution - Missense	Oesophagus
COSM3743889	c.428C>T	p.A143V	Substitution - Missense	Liver
COSM1662712	c.1619C>A	p.A540D	Substitution - Missense	Kidney
COSM3567432	c.938C>T	p.P313L	Substitution - Missense	Skin
COSM4136067	c.1360G>C	p.E454Q	Substitution - Missense	Breast
COSM3296137	c.1536C>T	p.S512S	Substitution - coding silent	Skin
COSM4446469	c.114-3C>A	p.?	Unknown	Skin
COSM276010	c.3425C>T	p.A1142V	Substitution - Missense	Large_intestine
COSM570471	c.3598G>T	p.E1200*	Substitution - Nonsense	Breast
COSM4600201	c.3440G>T	p.R1147L	Substitution - Missense	Upper_aerodigestive_tract
COSM4544187	c.3518G>A	p.G1173E	Substitution - Missense	Skin
COSM3567463	c.3928C>T	p.Q1310*	Substitution - Nonsense	Skin
COSM1399840	c.790A>C	p.S264R	Substitution - Missense	Large_intestine
COSM5599907	c.2762C>T	p.S921F	Substitution - Missense	Skin
COSM5952854	c.3190G>C	p.D1064H	Substitution - Missense	Oesophagus
COSM3296117	c.1120G>A	p.V374I	Substitution - Missense	Upper_aerodigestive_tract
COSM5734126	c.1468C>T	p.P490S	Substitution - Missense	Pancreas
COSM5734679	c.3608C>A	p.P1203H	Substitution - Missense	Pancreas
COSM5641654	c.46C>G	p.L16V	Substitution - Missense	Oesophagus
COSM1726308	c.1419G>C	p.M473I	Substitution - Missense	Liver
COSM3567438	c.1306C>T	p.P436S	Substitution - Missense	Skin
COSM3567450	c.2417C>T	p.S806F	Substitution - Missense	Skin
COSM5994293	c.3284C>T	p.A1095V	Substitution - Missense	Prostate
COSM3567434	c.1102C>T	p.P368S	Substitution - Missense	Skin
COSM1007235	c.3009C>T	p.C1003C	Substitution - coding silent	Endometrium
COSM4544187	c.3518G>A	p.G1173E	Substitution - Missense	Skin
COSM4700978	c.124T>G	p.S42A	Substitution - Missense	Large_intestine
COSM1214642	c.2689G>A	p.A897T	Substitution - Missense	Biliary_tract
COSM5772401	c.3784G>C	p.E1262Q	Substitution - Missense	Breast
COSM3798026	c.4435G>A	p.D1479N	Substitution - Missense	Urinary_tract
COSM1305686	c.930G>C	p.M310I	Substitution - Missense	Urinary_tract
COSM3567457	c.3124C>T	p.P1042S	Substitution - Missense	Skin
COSM1007213	c.421C>T	p.R141W	Substitution - Missense	Endometrium
COSM4490676	c.3677C>T	p.P1226L	Substitution - Missense	Skin
COSM3296123	c.1224A>T	p.P408P	Substitution - coding silent	Upper_aerodigestive_tract
COSM124348	c.3253G>A	p.V1085I	Substitution - Missense	Pancreas
COSM3296126	c.1276G>A	p.V426I	Substitution - Missense	Upper_aerodigestive_tract
COSM334384	c.3427G>T	p.V1143F	Substitution - Missense	Lung
COSM3296124	c.1248C>T	p.H416H	Substitution - coding silent	Upper_aerodigestive_tract
COSM5650773	c.1918G>T	p.G640C	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1399843	c.1423C>T	p.P475S	Substitution - Missense	Large_intestine
COSM1007237	c.3498G>A	p.L1166L	Substitution - coding silent	Endometrium
COSM5572408	c.544T>C	p.Y182H	Substitution - Missense	Prostate
COSM5901150	c.2519-8C>T	p.?	Unknown	Skin
COSM3296117	c.1120G>A	p.V374I	Substitution - Missense	Upper_aerodigestive_tract
COSM3296120	c.1171A>G	p.M391V	Substitution - Missense	Upper_aerodigestive_tract
COSM3296124	c.1248C>T	p.H416H	Substitution - coding silent	Upper_aerodigestive_tract
COSM5713609	c.1255C>A	p.H419N	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3567470	c.4414-1G>A	p.?	Unknown	Skin
COSM3296123	c.1224A>T	p.P408P	Substitution - coding silent	Upper_aerodigestive_tract
COSM3425267	c.2762C>A	p.S921Y	Substitution - Missense	Large_intestine
COSM5572408	c.544T>C	p.Y182H	Substitution - Missense	Prostate
COSM173042	c.4158C>T	p.G1386G	Substitution - coding silent	Central_nervous_system
COSM397165	c.2010C>T	p.L670L	Substitution - coding silent	Lung
COSM5611993	c.904A>G	p.T302A	Substitution - Missense	Adrenal_gland
COSM378312	c.3337C>G	p.Q1113E	Substitution - Missense	Lung
COSM3567455	c.2933C>T	p.P978L	Substitution - Missense	Skin
COSM1257403	c.2023A>G	p.M675V	Substitution - Missense	Oesophagus
COSM288609	c.3755G>T	p.R1252I	Substitution - Missense	Stomach
COSM3567455	c.2933C>T	p.P978L	Substitution - Missense	Skin
COSM4979974	c.1367C>T	p.S456L	Substitution - Missense	Oesophagus
COSM1195766	c.2057A>G	p.D686G	Substitution - Missense	Lung
COSM3567449	c.2089C>T	p.P697S	Substitution - Missense	Skin
COSM1738679	c.709A>G	p.I237V	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM716475	c.1340G>A	p.G447E	Substitution - Missense	Lung
COSM3296117	c.1120G>A	p.V374I	Substitution - Missense	Upper_aerodigestive_tract
COSM5502537	c.1750G>T	p.A584S	Substitution - Missense	Biliary_tract
COSM1325882	c.4302G>A	p.L1434L	Substitution - coding silent	Ovary
COSM3296126	c.1276G>A	p.V426I	Substitution - Missense	Upper_aerodigestive_tract
COSM3567441	c.1385C>T	p.S462L	Substitution - Missense	Skin
COSM305524	c.863C>G	p.S288C	Substitution - Missense	Central_nervous_system
COSM1399839	c.317T>G	p.I106S	Substitution - Missense	Large_intestine
COSM4085340	c.646G>T	p.G216C	Substitution - Missense	Stomach
COSM4490676	c.3677C>T	p.P1226L	Substitution - Missense	Skin
COSM3296128	c.1326C>A	p.P442P	Substitution - coding silent	Upper_aerodigestive_tract
COSM4405669	c.2887C>T	p.L963L	Substitution - coding silent	Skin
COSM3296120	c.1171A>G	p.M391V	Substitution - Missense	Upper_aerodigestive_tract
COSM3296140	c.1587A>G	p.I529M	Substitution - Missense	Upper_aerodigestive_tract
COSM4085338	c.83G>A	p.R28H	Substitution - Missense	Stomach
COSM3296118	c.1142T>C	p.F381S	Substitution - Missense	Large_intestine
COSM3567433	c.1048C>T	p.P350S	Substitution - Missense	Skin
COSM3567467	c.4179C>T	p.I1393I	Substitution - coding silent	Skin
COSM1399849	c.3377T>C	p.F1126S	Substitution - Missense	Large_intestine
COSM3836954	c.2232G>T	p.M744I	Substitution - Missense	Breast
COSM5588255	c.31G>T	p.D11Y	Substitution - Missense	Skin
COSM3567431	c.355C>T	p.P119S	Substitution - Missense	Skin
COSM3836953	c.1439A>T	p.Q480L	Substitution - Missense	Breast
COSM3296114	c.852T>C	p.P284P	Substitution - coding silent	Upper_aerodigestive_tract
COSM1399845	c.1501A>C	p.R501R	Substitution - coding silent	Large_intestine
COSM3738079	c.2173G>A	p.A725T	Substitution - Missense	Soft_tissue
COSM1007233	c.2903C>T	p.S968L	Substitution - Missense	Endometrium
COSM225158	c.1625C>T	p.P542L	Substitution - Missense	Skin
COSM3296117	c.1120G>A	p.V374I	Substitution - Missense	Upper_aerodigestive_tract
COSM3296123	c.1224A>T	p.P408P	Substitution - coding silent	Upper_aerodigestive_tract
COSM5630077	c.1801A>T	p.S601C	Substitution - Missense	Oesophagus
COSM1691144	c.1204C>T	p.P402S	Substitution - Missense	Skin
COSM335156	c.842A>G	p.H281R	Substitution - Missense	Large_intestine
COSM716472	c.2749A>G	p.S917G	Substitution - Missense	Lung
COSM1257402	c.3605_3606insC	p.R1204fs*22	Insertion - Frameshift	Oesophagus
COSM3894920	c.4320C>T	p.V1440V	Substitution - coding silent	Skin
COSM213215	c.3843G>C	p.E1281D	Substitution - Missense	Breast
COSM3567444	c.1504C>T	p.P502S	Substitution - Missense	Skin
COSM3296137	c.1536C>T	p.S512S	Substitution - coding silent	Upper_aerodigestive_tract
COSM3296180	c.2415T>C	p.N805N	Substitution - coding silent	Large_intestine
COSM3567447	c.1976G>A	p.R659K	Substitution - Missense	Skin
COSM3567459	c.3197C>T	p.S1066F	Substitution - Missense	Skin
COSM4954651	c.967A>G	p.I323V	Substitution - Missense	Liver
COSM3567429	c.50C>T	p.P17L	Substitution - Missense	Skin
COSM4085344	c.2553G>A	p.A851A	Substitution - coding silent	Stomach
COSM3567456	c.3055G>A	p.V1019M	Substitution - Missense	Skin
COSM1007231	c.2584A>G	p.T862A	Substitution - Missense	Endometrium
COSM4405569	c.3146T>G	p.L1049R	Substitution - Missense	Skin
COSM1007215	c.952T>C	p.S318P	Substitution - Missense	Endometrium
COSM3567454	c.2896C>T	p.L966L	Substitution - coding silent	Skin
COSM4911931	c.498T>C	p.N166N	Substitution - coding silent	Liver
COSM3296137	c.1536C>T	p.S512S	Substitution - coding silent	Skin
COSM1631318	c.701A>G	p.D234G	Substitution - Missense	Liver
COSM3406921	c.169G>A	p.D57N	Substitution - Missense	Central_nervous_system
COSM1399851	c.3580delA	p.K1195fs*22	Deletion - Frameshift	Large_intestine
COSM5394455	c.1872C>T	p.F624F	Substitution - coding silent	Skin
COSM371386	c.280G>A	p.E94K	Substitution - Missense	Lung
COSM4765455	c.3520_3521insA	p.N1175fs*9	Insertion - Frameshift	Stomach
COSM4570373	c.2671T>C	p.F891L	Substitution - Missense	Skin
COSM1168896	c.1446T>A	p.T482T	Substitution - coding silent	Pancreas
COSM1243396	c.3752C>T	p.P1251L	Substitution - Missense	Oesophagus
COSM4136067	c.1360G>C	p.E454Q	Substitution - Missense	Ovary
COSM5707778	c.4297G>C	p.G1433R	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5951516	c.4189A>G	p.T1397A	Substitution - Missense	Oesophagus
COSM3567468	c.4183G>A	p.G1395R	Substitution - Missense	Skin
COSM1007234	c.2904G>A	p.S968S	Substitution - coding silent	Endometrium
COSM3296126	c.1276G>A	p.V426I	Substitution - Missense	Upper_aerodigestive_tract
COSM3379791	c.24C>T	p.D8D	Substitution - coding silent	Pancreas
COSM338697	c.3296G>T	p.G1099V	Substitution - Missense	Lung
COSM3296126	c.1276G>A	p.V426I	Substitution - Missense	Upper_aerodigestive_tract
COSM3836955	c.2759G>A	p.S920N	Substitution - Missense	Breast
COSM5035681	c.306T>A	p.H102Q	Substitution - Missense	Oesophagus
COSM1752045	c.1113G>C	p.Q371H	Substitution - Missense	Urinary_tract
COSM716468	c.3547G>C	p.E1183Q	Substitution - Missense	Lung
COSM3567440	c.1372C>T	p.Q458*	Substitution - Nonsense	Skin
COSM4601314	c.644G>A	p.R215H	Substitution - Missense	Upper_aerodigestive_tract
COSM4897661	c.3823A>C	p.S1275R	Substitution - Missense	Skin
COSM4488982	c.3410C>T	p.S1137F	Substitution - Missense	Skin
COSM3296137	c.1536C>T	p.S512S	Substitution - coding silent	Skin
COSM5599907	c.2762C>T	p.S921F	Substitution - Missense	Skin
COSM5629842	c.576A>G	p.Q192Q	Substitution - coding silent	Oesophagus
COSM1291312	c.4039G>A	p.G1347R	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5681836	c.387A>T	p.G129G	Substitution - coding silent	Soft_tissue
COSM3296124	c.1248C>T	p.H416H	Substitution - coding silent	Upper_aerodigestive_tract
COSM5812167	c.2401A>T	p.M801L	Substitution - Missense	Liver
COSM5665908	c.4079G>T	p.S1360I	Substitution - Missense	Soft_tissue
COSM4775970	c.3290G>T	p.S1097I	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM273743	c.3344_3345insC	p.I1117fs*16	Insertion - Frameshift	Large_intestine
COSM1007220	c.1457T>C	p.I486T	Substitution - Missense	Endometrium
COSM5749818	c.589G>C	p.V197L	Substitution - Missense	Genital_tract
COSM3379792	c.1371C>T	p.P457P	Substitution - coding silent	Pancreas
COSM5927232	c.1564C>T	p.P522S	Substitution - Missense	Skin
COSM124348	c.3253G>A	p.V1085I	Substitution - Missense	Upper_aerodigestive_tract
COSM3296120	c.1171A>G	p.M391V	Substitution - Missense	Upper_aerodigestive_tract
COSM3567449	c.2089C>T	p.P697S	Substitution - Missense	Skin
COSM5548412	c.3355G>T	p.A1119S	Substitution - Missense	Prostate
COSM3296120	c.1171A>G	p.M391V	Substitution - Missense	Upper_aerodigestive_tract
COSM4975356	c.2797C>T	p.L933F	Substitution - Missense	Oesophagus
COSM3836956	c.3532G>A	p.E1178K	Substitution - Missense	Breast
COSM3296123	c.1224A>T	p.P408P	Substitution - coding silent	Upper_aerodigestive_tract
COSM3296123	c.1224A>T	p.P408P	Substitution - coding silent	Upper_aerodigestive_tract
COSM3567466	c.4019T>G	p.F1340C	Substitution - Missense	Skin
COSM3296115	c.882G>A	p.R294R	Substitution - coding silent	Upper_aerodigestive_tract
COSM3567443	c.1486A>G	p.T496A	Substitution - Missense	Skin
COSM1214641	c.2158A>G	p.T720A	Substitution - Missense	Large_intestine
COSM3296145	c.1643G>A	p.S548N	Substitution - Missense	Upper_aerodigestive_tract
COSM1007236	c.3226G>A	p.V1076I	Substitution - Missense	Endometrium
COSM1007239	c.3660C>T	p.G1220G	Substitution - coding silent	Endometrium
COSM3296120	c.1171A>G	p.M391V	Substitution - Missense	Upper_aerodigestive_tract
COSM3567435	c.1125C>T	p.I375I	Substitution - coding silent	Skin
COSM1007229	c.2273C>T	p.A758V	Substitution - Missense	Endometrium
COSM5353908	c.467delT	p.T157fs*4	Deletion - Frameshift	Large_intestine
COSM5601790	c.3472C>T	p.L1158L	Substitution - coding silent	Skin
COSM3567448	c.2059T>C	p.L687L	Substitution - coding silent	Skin
COSM1186021	c.1150A>G	p.N384D	Substitution - Missense	Lung
COSM5599907	c.2762C>T	p.S921F	Substitution - Missense	Skin
COSM4085343	c.2306T>C	p.V769A	Substitution - Missense	Stomach
COSM5572408	c.544T>C	p.Y182H	Substitution - Missense	Prostate
COSM3296180	c.2415T>C	p.N805N	Substitution - coding silent	Upper_aerodigestive_tract
COSM371386	c.280G>A	p.E94K	Substitution - Missense	Skin
COSM3296128	c.1326C>A	p.P442P	Substitution - coding silent	Upper_aerodigestive_tract
COSM1007219	c.1424C>A	p.P475Q	Substitution - Missense	Endometrium
COSM3296140	c.1587A>G	p.I529M	Substitution - Missense	Upper_aerodigestive_tract
COSM3364300	c.1328T>C	p.V443A	Substitution - Missense	Kidney
COSM1641661	c.868G>T	p.A290S	Substitution - Missense	Stomach
COSM5889718	c.2651C>T	p.P884L	Substitution - Missense	Skin
COSM3372429	c.2716T>C	p.S906P	Substitution - Missense	Thyroid
COSM108209	c.4467G>A	p.R1489R	Substitution - coding silent	Skin
COSM3708940	c.30G>T	p.G10G	Substitution - coding silent	Liver
COSM1007222	c.1569C>A	p.N523K	Substitution - Missense	Endometrium
COSM4886108	c.3416C>A	p.A1139D	Substitution - Missense	Upper_aerodigestive_tract
COSM5917675	c.1466C>T	p.P489L	Substitution - Missense	Skin
COSM1007221	c.1476A>G	p.S492S	Substitution - coding silent	Prostate
COSM109568	c.1405C>T	p.H469Y	Substitution - Missense	Skin
COSM1007232	c.2604C>T	p.G868G	Substitution - coding silent	Large_intestine
COSM5648761	c.4437C>T	p.D1479D	Substitution - coding silent	Oesophagus
COSM5930937	c.3578C>T	p.S1193F	Substitution - Missense	Skin
COSM321602	c.1705C>T	p.H569Y	Substitution - Missense	Lung
COSM5922175	c.2510C>T	p.S837F	Substitution - Missense	Skin
COSM5423503	c.251_252delAG	p.R85fs*6	Deletion - Frameshift	Prostate
COSM3567455	c.2933C>T	p.P978L	Substitution - Missense	Skin
COSM3567446	c.1873C>T	p.P625S	Substitution - Missense	Skin
COSM1691146	c.1522C>T	p.P508S	Substitution - Missense	Skin
COSM5567742	c.678A>T	p.S226S	Substitution - coding silent	Prostate
COSM288609	c.3755G>T	p.R1252I	Substitution - Missense	Large_intestine
COSM441202	c.1173G>C	p.M391I	Substitution - Missense	Breast
COSM4085352	c.3865C>T	p.H1289Y	Substitution - Missense	Stomach
COSM1214646	c.1649C>A	p.S550Y	Substitution - Missense	Large_intestine
COSM3296124	c.1248C>T	p.H416H	Substitution - coding silent	Upper_aerodigestive_tract
COSM1007209	c.127T>G	p.L43V	Substitution - Missense	Endometrium
COSM1007212	c.257C>T	p.T86I	Substitution - Missense	Endometrium
COSM1752045	c.1113G>C	p.Q371H	Substitution - Missense	Urinary_tract
COSM3668821	c.3852G>A	p.V1284V	Substitution - coding silent	Liver
COSM299326	c.1695C>A	p.I565I	Substitution - coding silent	Large_intestine
COSM3296117	c.1120G>A	p.V374I	Substitution - Missense	Upper_aerodigestive_tract
COSM271384	c.3014C>A	p.A1005D	Substitution - Missense	Large_intestine
COSM3296209	c.3587A>G	p.Q1196R	Substitution - Missense	Lung
COSM1007228	c.2258C>A	p.P753H	Substitution - Missense	Endometrium
COSM3567455	c.2933C>T	p.P978L	Substitution - Missense	Skin
COSM4954651	c.967A>G	p.I323V	Substitution - Missense	Liver
COSM3296106	c.599G>A	p.R200Q	Substitution - Missense	Skin
COSM1286117	c.444A>T	p.V148V	Substitution - coding silent	Autonomic_ganglia
COSM3296123	c.1224A>T	p.P408P	Substitution - coding silent	Upper_aerodigestive_tract
COSM1007214	c.841C>T	p.H281Y	Substitution - Missense	Endometrium
COSM3894916	c.1093C>T	p.P365S	Substitution - Missense	Skin
COSM5507087	c.1890G>C	p.M630I	Substitution - Missense	Biliary_tract
COSM3296123	c.1224A>T	p.P408P	Substitution - coding silent	Upper_aerodigestive_tract
COSM3296181	c.2418C>A	p.S806S	Substitution - coding silent	Upper_aerodigestive_tract
COSM5520645	c.3887G>T	p.R1296L	Substitution - Missense	Biliary_tract
COSM5005659	c.3896G>A	p.R1299Q	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4085339	c.541C>T	p.L181L	Substitution - coding silent	Stomach
COSM3296146	c.1645A>G	p.S549G	Substitution - Missense	Upper_aerodigestive_tract
COSM350382	c.2599G>A	p.D867N	Substitution - Missense	Lung
COSM1257405	c.4403T>C	p.M1468T	Substitution - Missense	Oesophagus
COSM4799888	c.3471G>T	p.R1157S	Substitution - Missense	Liver
COSM1305685	c.400G>C	p.A134P	Substitution - Missense	Urinary_tract
COSM3296181	c.2418C>A	p.S806S	Substitution - coding silent	Upper_aerodigestive_tract
COSM4085342	c.2305G>A	p.V769I	Substitution - Missense	Stomach
COSM5505138	c.2162C>T	p.P721L	Substitution - Missense	Biliary_tract
COSM5465117	c.2474C>T	p.P825L	Substitution - Missense	Large_intestine
COSM1007224	c.1982A>T	p.Q661L	Substitution - Missense	Endometrium
COSM716476	c.969A>G	p.I323M	Substitution - Missense	Lung
COSM716468	c.3547G>C	p.E1183Q	Substitution - Missense	Lung
COSM5394454	c.64C>T	p.P22S	Substitution - Missense	Skin
COSM5665909	c.4133A>G	p.Y1378C	Substitution - Missense	Soft_tissue
COSM3296124	c.1248C>T	p.H416H	Substitution - coding silent	Stomach
COSM297240	c.2982G>A	p.A994A	Substitution - coding silent	Large_intestine
COSM3668821	c.3852G>A	p.V1284V	Substitution - coding silent	Liver
COSM3296137	c.1536C>T	p.S512S	Substitution - coding silent	Upper_aerodigestive_tract
COSM1007241	c.3887G>A	p.R1296Q	Substitution - Missense	Endometrium
COSM3894917	c.2084C>T	p.S695L	Substitution - Missense	Skin
COSM3296128	c.1326C>A	p.P442P	Substitution - coding silent	Upper_aerodigestive_tract
COSM1399841	c.930_931insA	p.P313fs*4	Insertion - Frameshift	Large_intestine
COSM1186022	c.1846G>A	p.G616R	Substitution - Missense	Lung
COSM3296144	c.1633T>C	p.S545P	Substitution - Missense	Upper_aerodigestive_tract
COSM1399844	c.1427C>T	p.P476L	Substitution - Missense	Large_intestine
COSM3567438	c.1306C>T	p.P436S	Substitution - Missense	Skin
COSM3798025	c.4216G>C	p.E1406Q	Substitution - Missense	Urinary_tract
COSM5547378	c.2349_2352delAATA	p.N785fs*18	Deletion - Frameshift	Prostate
COSM124349	c.3494G>A	p.R1165Q	Substitution - Missense	Upper_aerodigestive_tract
COSM397683	c.1947G>A	p.M649I	Substitution - Missense	Lung
COSM1007238	c.3637G>A	p.E1213K	Substitution - Missense	Skin
COSM1007242	c.4167C>A	p.V1389V	Substitution - coding silent	Endometrium
COSM5729201	c.8G>A	p.G3E	Substitution - Missense	Skin
COSM1007230	c.2294A>G	p.N765S	Substitution - Missense	Endometrium
COSM4550740	c.507G>T	p.K169N	Substitution - Missense	Skin
COSM4846907	c.2845+9G>C	p.?	Unknown	Cervix
COSM5772401	c.3784G>C	p.E1262Q	Substitution - Missense	Breast
COSM1325883	c.3239C>T	p.P1080L	Substitution - Missense	Ovary
COSM4700981	c.3562G>A	p.A1188T	Substitution - Missense	Large_intestine
COSM1007211	c.158A>G	p.Y53C	Substitution - Missense	Endometrium
COSM81410	c.3906A>C	p.G1302G	Substitution - coding silent	Ovary
COSM3296120	c.1171A>G	p.M391V	Substitution - Missense	Upper_aerodigestive_tract
COSM3296141	c.1588A>G	p.S530G	Substitution - Missense	Large_intestine
COSM240613	c.2308C>T	p.H770Y	Substitution - Missense	Prostate
COSM1691145	c.1205C>T	p.P402L	Substitution - Missense	Skin
COSM3296180	c.2415T>C	p.N805N	Substitution - coding silent	Upper_aerodigestive_tract
COSM5599907	c.2762C>T	p.S921F	Substitution - Missense	Skin
COSM3971606	c.2275G>A	p.V759M	Substitution - Missense	Central_nervous_system
COSM1214642	c.2689G>A	p.A897T	Substitution - Missense	Large_intestine
COSM3567437	c.1296C>T	p.T432T	Substitution - coding silent	Skin
COSM1007216	c.1005C>A	p.G335G	Substitution - coding silent	Endometrium
COSM1007238	c.3637G>A	p.E1213K	Substitution - Missense	Endometrium
COSM3296126	c.1276G>A	p.V426I	Substitution - Missense	Upper_aerodigestive_tract
COSM3567465	c.4002C>T	p.I1334I	Substitution - coding silent	Skin
COSM4136068	c.4337A>T	p.K1446I	Substitution - Missense	Ovary
COSM3990639	c.3832G>A	p.E1278K	Substitution - Missense	Kidney
COSM1481992	c.2205C>T	p.N735N	Substitution - coding silent	Breast
COSM5598485	c.2929C>T	p.P977S	Substitution - Missense	Skin
COSM1644766	c.2660G>A	p.S887N	Substitution - Missense	Salivary_gland
COSM3567439	c.1313C>T	p.P438L	Substitution - Missense	Skin
COSM4085347	c.3183G>A	p.P1061P	Substitution - coding silent	Stomach
COSM380161	c.2238T>C	p.S746S	Substitution - coding silent	Lung
COSM124347	c.2960A>C	p.Q987P	Substitution - Missense	Upper_aerodigestive_tract
COSM3296211	c.3609C>T	p.P1203P	Substitution - coding silent	Skin
COSM4085349	c.3520A>G	p.K1174E	Substitution - Missense	Stomach
COSM1214640	c.1562T>A	p.I521N	Substitution - Missense	Large_intestine
COSM3567461	c.3666C>T	p.I1222I	Substitution - coding silent	Skin
COSM5887704	c.771T>A	p.F257L	Substitution - Missense	Upper_aerodigestive_tract
COSM3894919	c.2668C>T	p.P890S	Substitution - Missense	Skin
COSM266905	c.1456A>G	p.I486V	Substitution - Missense	Large_intestine
COSM4569527	c.1815T>C	p.S605S	Substitution - coding silent	Skin
COSM1257404	c.1519A>T	p.S507C	Substitution - Missense	Oesophagus
COSM1727928	c.4249C>T	p.P1417S	Substitution - Missense	Liver
COSM3296152	c.1833T>C	p.S611S	Substitution - coding silent	Upper_aerodigestive_tract
COSM3567452	c.2731C>T	p.P911S	Substitution - Missense	Skin
COSM3296117	c.1120G>A	p.V374I	Substitution - Missense	Upper_aerodigestive_tract
COSM3296199	c.3140C>G	p.T1047S	Substitution - Missense	Large_intestine
COSM3567458	c.3134C>T	p.P1045L	Substitution - Missense	Skin
COSM5927233	c.2464C>T	p.P822S	Substitution - Missense	Skin
COSM3296200	c.3209A>G	p.Q1070R	Substitution - Missense	Large_intestine
COSM3567451	c.2695C>T	p.H899Y	Substitution - Missense	Skin
COSM1305685	c.400G>C	p.A134P	Substitution - Missense	Urinary_tract
COSM5572408	c.544T>C	p.Y182H	Substitution - Missense	Prostate
COSM5353908	c.467delT	p.T157fs*4	Deletion - Frameshift	Large_intestine
COSM3296119	c.1164G>T	p.Q388H	Substitution - Missense	Large_intestine
COSM3296180	c.2415T>C	p.N805N	Substitution - coding silent	Upper_aerodigestive_tract
COSM4799888	c.3471G>T	p.R1157S	Substitution - Missense	Liver
COSM3567453	c.2772C>T	p.I924I	Substitution - coding silent	Skin
COSM3296139	c.1574T>A	p.L525*	Substitution - Nonsense	Large_intestine
COSM1691148	c.3652C>T	p.H1218Y	Substitution - Missense	Skin
COSM3296117	c.1120G>A	p.V374I	Substitution - Missense	Upper_aerodigestive_tract
COSM4085346	c.2743A>T	p.N915Y	Substitution - Missense	Stomach
COSM331261	c.2725C>T	p.H909Y	Substitution - Missense	Lung
COSM5684688	c.2736C>A	p.H912Q	Substitution - Missense	Soft_tissue
COSM3296123	c.1224A>T	p.P408P	Substitution - coding silent	Upper_aerodigestive_tract
COSM3296114	c.852T>C	p.P284P	Substitution - coding silent	Upper_aerodigestive_tract
COSM3567469	c.4207T>A	p.L1403I	Substitution - Missense	Skin
COSM1214645	c.337C>A	p.H113N	Substitution - Missense	Large_intestine
COSM716469	c.3463G>T	p.D1155Y	Substitution - Missense	Lung
COSM3296115	c.882G>A	p.R294R	Substitution - coding silent	Upper_aerodigestive_tract
COSM1399853	c.3983C>A	p.S1328Y	Substitution - Missense	Large_intestine
COSM716471	c.2903C>A	p.S968*	Substitution - Nonsense	Lung
COSM4919177	c.3624C>A	p.N1208K	Substitution - Missense	Liver
COSM1007221	c.1476A>G	p.S492S	Substitution - coding silent	Endometrium
COSM4700980	c.3153delT	p.Q1053fs*19	Deletion - Frameshift	Large_intestine
COSM1007218	c.1231A>G	p.T411A	Substitution - Missense	Endometrium
COSM1399850	c.3579_3580insA	p.Q1196fs*30	Insertion - Frameshift	Large_intestine
COSM3567462	c.3792C>T	p.F1264F	Substitution - coding silent	Skin
COSM4085345	c.2605G>A	p.V869I	Substitution - Missense	Stomach
COSM1007227	c.2235C>A	p.N745K	Substitution - Missense	Endometrium
COSM5733487	c.1012C>T	p.P338S	Substitution - Missense	Pancreas
COSM3743890	c.4365A>C	p.E1455D	Substitution - Missense	Liver
COSM4488547	c.3348C>T	p.P1116P	Substitution - coding silent	Skin
COSM3296137	c.1536C>T	p.S512S	Substitution - coding silent	Skin
COSM5394456	c.2225C>T	p.P742L	Substitution - Missense	Skin
COSM3296142	c.1599A>C	p.L533L	Substitution - coding silent	Upper_aerodigestive_tract
COSM3296137	c.1536C>T	p.S512S	Substitution - coding silent	Upper_aerodigestive_tract
COSM3296208	c.3373G>A	p.A1125T	Substitution - Missense	Large_intestine
COSM3713462	c.2884C>T	p.Q962*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM3567445	c.1537G>A	p.D513N	Substitution - Missense	Skin
COSM1007217	c.1081C>T	p.L361F	Substitution - Missense	Endometrium
COSM3296115	c.882G>A	p.R294R	Substitution - coding silent	Upper_aerodigestive_tract
COSM5973369	c.103C>T	p.L35F	Substitution - Missense	Upper_aerodigestive_tract
COSM4085348	c.3383C>T	p.A1128V	Substitution - Missense	Stomach
COSM3567442	c.1416C>T	p.F472F	Substitution - coding silent	Skin
COSM3567434	c.1102C>T	p.P368S	Substitution - Missense	Skin
COSM5394458	c.2537C>T	p.S846F	Substitution - Missense	Skin
COSM3296128	c.1326C>A	p.P442P	Substitution - coding silent	Upper_aerodigestive_tract
COSM71586	c.3244G>T	p.D1082Y	Substitution - Missense	Ovary
COSM3296120	c.1171A>G	p.M391V	Substitution - Missense	Upper_aerodigestive_tract
COSM3296145	c.1643G>A	p.S548N	Substitution - Missense	Upper_aerodigestive_tract
COSM4085353	c.4408G>T	p.G1470W	Substitution - Missense	Stomach
COSM4085351	c.3808A>G	p.K1270E	Substitution - Missense	Stomach
COSM716473	c.2482A>T	p.I828F	Substitution - Missense	Lung
COSM4085341	c.1736T>G	p.L579*	Substitution - Nonsense	Stomach
COSM5966029	c.3547G>A	p.E1183K	Substitution - Missense	Breast
COSM3296168	c.2175C>A	p.A725A	Substitution - coding silent	Upper_aerodigestive_tract
COSM1691147	c.3092G>A	p.R1031K	Substitution - Missense	Skin
COSM3296126	c.1276G>A	p.V426I	Substitution - Missense	Upper_aerodigestive_tract
COSM5572408	c.544T>C	p.Y182H	Substitution - Missense	Prostate
COSM3296167	c.2174C>G	p.A725G	Substitution - Missense	Upper_aerodigestive_tract
COSM3296115	c.882G>A	p.R294R	Substitution - coding silent	Upper_aerodigestive_tract
COSM441204	c.3400T>C	p.L1134L	Substitution - coding silent	Breast
COSM282694	c.4028A>G	p.K1343R	Substitution - Missense	Large_intestine
COSM3567462	c.3792C>T	p.F1264F	Substitution - coding silent	Skin
COSM5497656	c.2552C>T	p.A851V	Substitution - Missense	Biliary_tract
COSM1007223	c.1896C>T	p.L632L	Substitution - coding silent	Endometrium
COSM3708940	c.30G>T	p.G10G	Substitution - coding silent	Liver
COSM4582684	c.2964G>T	p.G988G	Substitution - coding silent	Bone
COSM3567451	c.2695C>T	p.H899Y	Substitution - Missense	Skin
COSM321603	c.1834G>T	p.G612C	Substitution - Missense	Lung
COSM5994068	c.340A>G	p.K114E	Substitution - Missense	Prostate
COSM4516090	c.1570_1571CC>TT	p.P524L	Substitution - Missense	Skin
COSM3713462	c.2884C>T	p.Q962*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM5058122	c.3778C>A	p.L1260I	Substitution - Missense	Stomach
COSM4403229	c.433C>T	p.P145S	Substitution - Missense	Skin
COSM1186023	c.3253G>C	p.V1085L	Substitution - Missense	Lung
COSM108512	c.3043C>T	p.Q1015*	Substitution - Nonsense	Skin
COSM3296115	c.882G>A	p.R294R	Substitution - coding silent	Upper_aerodigestive_tract
COSM299325	c.208C>A	p.L70I	Substitution - Missense	Large_intestine
COSM4136069	c.4422A>G	p.Q1474Q	Substitution - coding silent	Ovary
COSM4975355	c.2701C>A	p.P901T	Substitution - Missense	Oesophagus
COSM5394459	c.3845A>G	p.N1282S	Substitution - Missense	Skin
COSM4637864	c.3252C>T	p.S1084S	Substitution - coding silent	Large_intestine
COSM1399853	c.3983C>A	p.S1328Y	Substitution - Missense	Large_intestine
COSM1318176	c.2940G>A	p.Q980Q	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM4844932	c.635C>G	p.S212C	Substitution - Missense	Cervix
COSM4700979	c.751A>G	p.T251A	Substitution - Missense	Large_intestine
COSM5458876	c.2457C>T	p.S819S	Substitution - coding silent	Large_intestine
COSM4085350	c.3633G>A	p.K1211K	Substitution - coding silent	Stomach
COSM5465116	c.1246C>A	p.H416N	Substitution - Missense	Large_intestine
COSM4833838	c.3727G>A	p.E1243K	Substitution - Missense	Cervix
COSM5597069	c.37G>A	p.E13K	Substitution - Missense	Skin
COSM3567455	c.2933C>T	p.P978L	Substitution - Missense	Skin
COSM3296142	c.1599A>C	p.L533L	Substitution - coding silent	Upper_aerodigestive_tract
COSM3567460	c.3210G>A	p.Q1070Q	Substitution - coding silent	Skin
COSM371827	c.2207A>T	p.Q736L	Substitution - Missense	Lung
COSM1157748	c.923C>T	p.P308L	Substitution - Missense	Pancreas
COSM4569288	c.1647T>C	p.S549S	Substitution - coding silent	Skin
COSM1691148	c.3652C>T	p.H1218Y	Substitution - Missense	Skin
COSM3296137	c.1536C>T	p.S512S	Substitution - coding silent	Upper_aerodigestive_tract
COSM716467	c.4099C>G	p.P1367A	Substitution - Missense	Lung
COSM3567430	c.354C>T	p.A118A	Substitution - coding silent	Skin
COSM5454911	c.3684T>C	p.H1228H	Substitution - coding silent	Large_intestine
COSM4840285	c.788C>A	p.S263Y	Substitution - Missense	Cervix
COSM1214643	c.990C>A	p.H330Q	Substitution - Missense	Large_intestine
COSM1186020	c.664C>T	p.P222S	Substitution - Missense	Lung
COSM1481993	c.3374C>T	p.A1125V	Substitution - Missense	Breast
COSM5803183	c.1525T>A	p.S509T	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3990638	c.526A>G	p.N176D	Substitution - Missense	Kidney
COSM3296176	c.2324T>C	p.V775A	Substitution - Missense	Large_intestine
COSM312766	c.547G>T	p.V183L	Substitution - Missense	Lung
COSM4918422	c.2034T>C	p.S678S	Substitution - coding silent	Liver
COSM4393836	c.2839G>A	p.G947R	Substitution - Missense	Skin
COSM3296120	c.1171A>G	p.M391V	Substitution - Missense	Upper_aerodigestive_tract
COSM1305687	c.1484C>G	p.S495*	Substitution - Nonsense	Urinary_tract
COSM3296139	c.1574T>A	p.L525*	Substitution - Nonsense	Large_intestine
COSM716477	c.956C>G	p.T319S	Substitution - Missense	Lung
COSM1399844	c.1427C>T	p.P476L	Substitution - Missense	Skin
COSM4387954	c.1084G>C	p.D362H	Substitution - Missense	Pancreas
COSM5599907	c.2762C>T	p.S921F	Substitution - Missense	Skin
COSM3567471	c.4425C>T	p.I1475I	Substitution - coding silent	Skin
COSM716474	c.2171G>A	p.G724E	Substitution - Missense	Lung
COSM3296124	c.1248C>T	p.H416H	Substitution - coding silent	Upper_aerodigestive_tract
COSM282695	c.4183G>T	p.G1395*	Substitution - Nonsense	Large_intestine
COSM3296128	c.1326C>A	p.P442P	Substitution - coding silent	Upper_aerodigestive_tract
COSM3296117	c.1120G>A	p.V374I	Substitution - Missense	Upper_aerodigestive_tract
COSM1007226	c.2105C>A	p.S702Y	Substitution - Missense	Endometrium
COSM3296114	c.852T>C	p.P284P	Substitution - coding silent	Upper_aerodigestive_tract
COSM4975354	c.2644C>T	p.Q882*	Substitution - Nonsense	Oesophagus
COSM272930	c.3720G>A	p.L1240L	Substitution - coding silent	Large_intestine
COSM3296105	c.591C>A	p.V197V	Substitution - coding silent	Large_intestine
COSM3296181	c.2418C>A	p.S806S	Substitution - coding silent	Upper_aerodigestive_tract
COSM3296240	c.4315C>A	p.R1439S	Substitution - Missense	Central_nervous_system
COSM3296115	c.882G>A	p.R294R	Substitution - coding silent	Upper_aerodigestive_tract
COSM4492873	c.4054C>T	p.P1352S	Substitution - Missense	Skin
COSM5394457	c.2378G>C	p.C793S	Substitution - Missense	Skin
COSM1691146	c.1522C>T	p.P508S	Substitution - Missense	Skin
COSM3990640	c.4140A>C	p.P1380P	Substitution - coding silent	Kidney
COSM390152	c.3057G>A	p.V1019V	Substitution - coding silent	Lung
COSM1007210	c.145C>T	p.Q49*	Substitution - Nonsense	Endometrium
COSM716478	c.760A>T	p.N254Y	Substitution - Missense	Lung
COSM3567450	c.2417C>T	p.S806F	Substitution - Missense	Skin
COSM5685302	c.3597G>C	p.G1199G	Substitution - coding silent	Soft_tissue
COSM4388398	c.668G>A	p.S223N	Substitution - Missense	Pancreas
COSM1325884	c.1145A>C	p.H382P	Substitution - Missense	Ovary
COSM335156	c.842A>G	p.H281R	Substitution - Missense	Lung
COSM3296128	c.1326C>A	p.P442P	Substitution - coding silent	Upper_aerodigestive_tract
COSM124348	c.3253G>A	p.V1085I	Substitution - Missense	Oesophagus
COSM3296120	c.1171A>G	p.M391V	Substitution - Missense	Upper_aerodigestive_tract
COSM3971606	c.2275G>A	p.V759M	Substitution - Missense	Large_intestine
COSM1007232	c.2604C>T	p.G868G	Substitution - coding silent	Endometrium
COSM4483255	c.2688C>T	p.H896H	Substitution - coding silent	Skin
COSM4489621	c.3501C>T	p.P1167P	Substitution - coding silent	Skin
COSM166111	c.2371delG	p.N792fs*12	Deletion - Frameshift	Breast
COSM3296124	c.1248C>T	p.H416H	Substitution - coding silent	Upper_aerodigestive_tract
COSM3567464	c.3962C>T	p.S1321F	Substitution - Missense	Skin
COSM1007240	c.3690G>A	p.R1230R	Substitution - coding silent	Endometrium
COSM3567433	c.1048C>T	p.P350S	Substitution - Missense	Stomach
COSM1214644	c.3260C>T	p.A1087V	Substitution - Missense	Large_intestine

> Text Mining based Variations [ TOP ]
There is no record for MBD5.

Summary
Symbol	MBD5
Name	methyl-CpG binding domain protein 5
Aliases	FLJ11113; KIAA1461; MRD1; methyl-CpG-binding protein MBD5; Methyl-CpG-binding domain protein 5
Location	2q23.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM) [ TOP ]
There is no PTM data

Summary
Symbol	MBD5
Name	methyl-CpG binding domain protein 5
Aliases	FLJ11113; KIAA1461; MRD1; methyl-CpG-binding protein MBD5; Methyl-CpG-binding domain protein 5
Location	2q23.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	4.192	3.076	-1.155	7.65e-10	Under
BRCA	Breast invasive carcinoma	112	1100	4.336	3.939	-0.38	6.81e-10	NS
CESC	Cervical and endocervical cancers	3	306	3.765	2.89	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	3.284	2.952	-0.415	1.04e-05	NS
ESCA	Esophageal carcinoma	11	185	4.448	3.979	-0.716	0.00538	Under
GBM	Glioblastoma multiforme	5	166	4.328	3.973	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	3.073	2.894	-0.249	0.0297	NS
KIRC	Kidney renal clear cell carcinoma	72	534	4.517	4.336	-0.175	0.00835	NS
KIRP	Kidney renal papillary cell carcinoma	32	291	4.317	4.191	-0.144	0.269	NS
LAML	Acute Myeloid Leukemia	0	173	NA	4.308	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	4.561	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	1.834	1.919	0.086	0.516	NS
LUAD	Lung adenocarcinoma	59	517	3.743	3.479	-0.222	0.0062	NS
LUSC	Lung squamous cell carcinoma	51	501	3.768	3.156	-0.613	8.91e-09	Under
OV	Ovarian serous cystadenocarcinoma	0	307	NA	4.332	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	3.684	3.659	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	3.906	4.437	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	3.999	3.591	-0.504	8.96e-09	NS
READ	Rectum adenocarcinoma	10	167	3.595	3.07	-0.613	0.00211	Under
SARC	Sarcoma	2	263	4.207	3.566	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	3.304	3.492	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	4.082	3.929	-0.437	0.000261	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	2.166	NA	NA	NA
THCA	Thyroid carcinoma	59	509	4.086	3.698	-0.367	2.45e-09	NS
THYM	Thymoma	2	120	4.073	3.777	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	3.864	3.505	-0.443	0.000141	NS

> Cancer Cell Line Encyclopedia (CCLE)

Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	6.9
Autonomic ganglia	CHP212	6.2
Autonomic ganglia	IMR32	4.9
Autonomic ganglia	KELLY	6.1
Autonomic ganglia	KPNRTBM1	7
Autonomic ganglia	KPNSI9S	6
Autonomic ganglia	KPNYN	6.3
Autonomic ganglia	MHHNB11	5
Autonomic ganglia	NB1	5.3
Autonomic ganglia	NH6	6.8
Autonomic ganglia	SHSY5Y	7.4
Autonomic ganglia	SIMA	6.4
Autonomic ganglia	SKNAS	6.5
Autonomic ganglia	SKNBE2	6.6
Autonomic ganglia	SKNDZ	5.8
Autonomic ganglia	SKNFI	6.3
Autonomic ganglia	SKNSH	5.6
Biliary tract	HUCCT1	4.5
Biliary tract	HUH28	5.3
Biliary tract	SNU1079	5.8
Biliary tract	SNU1196	4.2
Biliary tract	SNU245	4.2
Biliary tract	SNU308	5.3
Biliary tract	SNU478	4.1
Bone	143B	4.9
Bone	A673	5.1
Bone	CADOES1	5.8
Bone	CAL78	6.3
Bone	G292CLONEA141B1	7.4
Bone	HOS	5.3
Bone	HS706T	5.3
Bone	HS737T	6.8
Bone	HS819T	6.7
Bone	HS821T	6
Bone	HS822T	6.7
Bone	HS863T	6
Bone	HS870T	5.9
Bone	HS888T	6.2
Bone	MG63	5.8
Bone	MHHES1	7.5
Bone	OUMS27	4.9
Bone	RDES	5.8
Bone	SJSA1	5.4
Bone	SKES1	6
Bone	SKNMC	6.1
Bone	SW1353	6.5
Bone	T173	6.2
Bone	TC71	5
Bone	U2OS	4.4
Breast	AU565	4.5
Breast	BT20	3.9
Breast	BT474	5.3
Breast	BT483	5.9
Breast	BT549	4.6
Breast	CAL120	4.9
Breast	CAL148	5.7
Breast	CAL51	6.1
Breast	CAL851	4.6
Breast	CAMA1	7.1
Breast	DU4475	7.5
Breast	EFM192A	5.8
Breast	EFM19	3.9
Breast	EVSAT	4
Breast	HCC1143	4.6
Breast	HCC1187	5.7
Breast	HCC1395	3.9
Breast	HCC1419	5
Breast	HCC1428	4.3
Breast	HCC1500	4.8
Breast	HCC1569	4.8
Breast	HCC1599	4.6
Breast	HCC1806	4.8
Breast	HCC1937	4.1
Breast	HCC1954	5.4
Breast	HCC202	5
Breast	HCC2157	5.6
Breast	HCC2218	4.6
Breast	HCC38	4.7
Breast	HCC70	5.2
Breast	HDQP1	6.1
Breast	HMC18	4.5
Breast	HS274T	6
Breast	HS281T	5.8
Breast	HS343T	4.9
Breast	HS578T	4.4
Breast	HS606T	6.7
Breast	HS739T	5.6
Breast	HS742T	6.4
Breast	JIMT1	4
Breast	KPL1	5.5
Breast	MCF7	4.7
Breast	MDAMB134VI	5.9
Breast	MDAMB157	5.2
Breast	MDAMB175VII	4.7
Breast	MDAMB231	4.9
Breast	MDAMB361	4.1
Breast	MDAMB415	4.1
Breast	MDAMB436	4.3
Breast	MDAMB453	5.5
Breast	MDAMB468	5.9
Breast	SKBR3	4
Breast	T47D	4
Breast	UACC812	4.9
Breast	UACC893	4.4
Breast	YMB1	5.3
Breast	ZR751	5.5
Breast	ZR7530	5.8
Central nervous system	1321N1	4.6
Central nervous system	42MGBA	7
Central nervous system	8MGBA	5.2
Central nervous system	A172	7.3
Central nervous system	AM38	4.6
Central nervous system	BECKER	6.2
Central nervous system	CAS1	6.1
Central nervous system	CCFSTTG1	6.3
Central nervous system	D283MED	4.9
Central nervous system	D341MED	7.8
Central nervous system	DAOY	5.1
Central nervous system	DBTRG05MG	4.8
Central nervous system	DKMG	6.9
Central nervous system	GAMG	4.3
Central nervous system	GB1	4.2
Central nervous system	GI1	5.3
Central nervous system	GMS10	6.5
Central nervous system	GOS3	5.9
Central nervous system	H4	5.2
Central nervous system	HS683	6.3
Central nervous system	KALS1	6
Central nervous system	KG1C	6.9
Central nervous system	KNS42	6.7
Central nervous system	KNS60	4.2
Central nervous system	KNS81	5.9
Central nervous system	KS1	6.8
Central nervous system	LN18	4.5
Central nervous system	LN229	6.4
Central nervous system	M059K	6
Central nervous system	MOGGCCM	5.1
Central nervous system	MOGGUVW	4.1
Central nervous system	NMCG1	4.5
Central nervous system	ONS76	5.2
Central nervous system	SF126	4.5
Central nervous system	SF295	5
Central nervous system	SNB19	5.9
Central nervous system	SNU1105	5.9
Central nervous system	SNU201	6.5
Central nervous system	SNU466	4.9
Central nervous system	SNU489	5.6
Central nervous system	SNU626	5.8
Central nervous system	SNU738	4.4
Central nervous system	SW1088	5.5
Central nervous system	SW1783	6.3
Central nervous system	T98G	6
Central nervous system	TM31	5.4
Central nervous system	U118MG	4.5
Central nervous system	U138MG	5.6
Central nervous system	U251MG	7.2
Central nervous system	U87MG	5.7
Central nervous system	YH13	5.9
Central nervous system	YKG1	6.6
Endometrium	AN3CA	5.8
Endometrium	COLO684	6
Endometrium	EFE184	4.6
Endometrium	EN	4.9
Endometrium	ESS1	5.4
Endometrium	HEC108	5.9
Endometrium	HEC151	6.2
Endometrium	HEC1A	6.6
Endometrium	HEC1B	7.9
Endometrium	HEC251	4.4
Endometrium	HEC265	4.4
Endometrium	HEC50B	4.2
Endometrium	HEC59	5.3
Endometrium	HEC6	6.7
Endometrium	ISHIKAWAHERAKLIO02ER	5.4
Endometrium	JHUEM1	5
Endometrium	JHUEM2	5.3
Endometrium	JHUEM3	6.5
Endometrium	KLE	4.7
Endometrium	MFE280	5.2
Endometrium	MFE296	5.7
Endometrium	MFE319	5.7
Endometrium	RL952	5.3
Endometrium	SNGM	7.2
Endometrium	SNU1077	7.6
Endometrium	SNU685	5
Endometrium	TEN	5.8
Haematopoietic and lymphoid	697	5.6
Haematopoietic and lymphoid	A3KAW	5.7
Haematopoietic and lymphoid	A4FUK	5.7
Haematopoietic and lymphoid	ALLSIL	6.6
Haematopoietic and lymphoid	AML193	5.6
Haematopoietic and lymphoid	AMO1	4.4
Haematopoietic and lymphoid	BCP1	4.6
Haematopoietic and lymphoid	BDCM	7
Haematopoietic and lymphoid	BL41	4.3
Haematopoietic and lymphoid	BL70	4.5
Haematopoietic and lymphoid	BV173	4.1
Haematopoietic and lymphoid	CA46	6
Haematopoietic and lymphoid	CI1	5.3
Haematopoietic and lymphoid	CMK115	6.1
Haematopoietic and lymphoid	CMK86	6.4
Haematopoietic and lymphoid	CMK	5.6
Haematopoietic and lymphoid	CMLT1	6.4
Haematopoietic and lymphoid	COLO775	4.6
Haematopoietic and lymphoid	DAUDI	4.4
Haematopoietic and lymphoid	DB	5.2
Haematopoietic and lymphoid	DEL	5.3
Haematopoietic and lymphoid	DND41	5.7
Haematopoietic and lymphoid	DOHH2	4.9
Haematopoietic and lymphoid	EB1	5.6
Haematopoietic and lymphoid	EB2	6.4
Haematopoietic and lymphoid	EHEB	5.1
Haematopoietic and lymphoid	EJM	4
Haematopoietic and lymphoid	EM2	4.6
Haematopoietic and lymphoid	EOL1	4.3
Haematopoietic and lymphoid	F36P	6
Haematopoietic and lymphoid	GA10	5
Haematopoietic and lymphoid	GDM1	6.1
Haematopoietic and lymphoid	GRANTA519	5.9
Haematopoietic and lymphoid	HDLM2	5.1
Haematopoietic and lymphoid	HDMYZ	5.1
Haematopoietic and lymphoid	HEL9217	5.3
Haematopoietic and lymphoid	HEL	5.8
Haematopoietic and lymphoid	HH	4.3
Haematopoietic and lymphoid	HL60	4.2
Haematopoietic and lymphoid	HPBALL	6.2
Haematopoietic and lymphoid	HS604T	6.5
Haematopoietic and lymphoid	HS611T	5.2
Haematopoietic and lymphoid	HS616T	6.9
Haematopoietic and lymphoid	HS751T	5.9
Haematopoietic and lymphoid	HT	4.6
Haematopoietic and lymphoid	HTK	4.2
Haematopoietic and lymphoid	HUNS1	5.5
Haematopoietic and lymphoid	HUT102	5.2
Haematopoietic and lymphoid	HUT78	4.2
Haematopoietic and lymphoid	JEKO1	6
Haematopoietic and lymphoid	JK1	5.6
Haematopoietic and lymphoid	JM1	4.7
Haematopoietic and lymphoid	JURKAT	6.1
Haematopoietic and lymphoid	JURLMK1	4.6
Haematopoietic and lymphoid	JVM2	4.6
Haematopoietic and lymphoid	JVM3	5.3
Haematopoietic and lymphoid	K562	3.7
Haematopoietic and lymphoid	KARPAS299	6.6
Haematopoietic and lymphoid	KARPAS422	6
Haematopoietic and lymphoid	KARPAS620	3.9
Haematopoietic and lymphoid	KASUMI1	4.9
Haematopoietic and lymphoid	KASUMI2	5.8
Haematopoietic and lymphoid	KASUMI6	6
Haematopoietic and lymphoid	KCL22	5.6
Haematopoietic and lymphoid	KE37	5.8
Haematopoietic and lymphoid	KE97	5.8
Haematopoietic and lymphoid	KG1	5.7
Haematopoietic and lymphoid	KHM1B	4
Haematopoietic and lymphoid	KIJK	5.3
Haematopoietic and lymphoid	KMH2	4.7
Haematopoietic and lymphoid	KMM1	4.9
Haematopoietic and lymphoid	KMS11	4.6
Haematopoietic and lymphoid	KMS12BM	4.3
Haematopoietic and lymphoid	KMS18	6.7
Haematopoietic and lymphoid	KMS20	4.7
Haematopoietic and lymphoid	KMS21BM	7
Haematopoietic and lymphoid	KMS26	4.7
Haematopoietic and lymphoid	KMS27	4
Haematopoietic and lymphoid	KMS28BM	4.8
Haematopoietic and lymphoid	KMS34	5.3
Haematopoietic and lymphoid	KO52	7
Haematopoietic and lymphoid	KOPN8	3.9
Haematopoietic and lymphoid	KU812	6.9
Haematopoietic and lymphoid	KYO1	4
Haematopoietic and lymphoid	L1236	5.9
Haematopoietic and lymphoid	L363	6.6
Haematopoietic and lymphoid	L428	4.2
Haematopoietic and lymphoid	L540	4.1
Haematopoietic and lymphoid	LAMA84	4.9
Haematopoietic and lymphoid	LOUCY	6.6
Haematopoietic and lymphoid	LP1	4.4
Haematopoietic and lymphoid	M07E	6.3
Haematopoietic and lymphoid	MC116	4.1
Haematopoietic and lymphoid	ME1	4.8
Haematopoietic and lymphoid	MEC1	6.1
Haematopoietic and lymphoid	MEC2	4.9
Haematopoietic and lymphoid	MEG01	5.7
Haematopoietic and lymphoid	MHHCALL2	4.5
Haematopoietic and lymphoid	MHHCALL3	5.8
Haematopoietic and lymphoid	MHHCALL4	6.1
Haematopoietic and lymphoid	MINO	4.4
Haematopoietic and lymphoid	MJ	4.5
Haematopoietic and lymphoid	MM1S	5
Haematopoietic and lymphoid	MOLM13	4.1
Haematopoietic and lymphoid	MOLM16	6.2
Haematopoietic and lymphoid	MOLM6	6.2
Haematopoietic and lymphoid	MOLP2	4.4
Haematopoietic and lymphoid	MOLP8	6.3
Haematopoietic and lymphoid	MOLT13	6.4
Haematopoietic and lymphoid	MOLT16	5.9
Haematopoietic and lymphoid	MOLT4	5.2
Haematopoietic and lymphoid	MONOMAC1	5.3
Haematopoietic and lymphoid	MONOMAC6	4.7
Haematopoietic and lymphoid	MOTN1	4.8
Haematopoietic and lymphoid	MUTZ5	6.1
Haematopoietic and lymphoid	MV411	3.9
Haematopoietic and lymphoid	NALM19	4.9
Haematopoietic and lymphoid	NALM1	5.3
Haematopoietic and lymphoid	NALM6	5
Haematopoietic and lymphoid	NAMALWA	5.9
Haematopoietic and lymphoid	NB4	5.4
Haematopoietic and lymphoid	NCIH929	5.1
Haematopoietic and lymphoid	NCO2	6.5
Haematopoietic and lymphoid	NOMO1	5.6
Haematopoietic and lymphoid	NUDHL1	5.7
Haematopoietic and lymphoid	NUDUL1	5.2
Haematopoietic and lymphoid	OCIAML2	4.4
Haematopoietic and lymphoid	OCIAML3	6.2
Haematopoietic and lymphoid	OCIAML5	5
Haematopoietic and lymphoid	OCILY10	4.3
Haematopoietic and lymphoid	OCILY19	5.7
Haematopoietic and lymphoid	OCILY3	5.1
Haematopoietic and lymphoid	OCIM1	6.8
Haematopoietic and lymphoid	OPM2	6
Haematopoietic and lymphoid	P12ICHIKAWA	6.1
Haematopoietic and lymphoid	P31FUJ	5.1
Haematopoietic and lymphoid	P3HR1	3.9
Haematopoietic and lymphoid	PCM6	5.1
Haematopoietic and lymphoid	PEER	5
Haematopoietic and lymphoid	PF382	6
Haematopoietic and lymphoid	PFEIFFER	4.1
Haematopoietic and lymphoid	PL21	6.1
Haematopoietic and lymphoid	RAJI	4
Haematopoietic and lymphoid	RCHACV	6.5
Haematopoietic and lymphoid	REC1	4.7
Haematopoietic and lymphoid	REH	6.2
Haematopoietic and lymphoid	RI1	4.4
Haematopoietic and lymphoid	RL	4.8
Haematopoietic and lymphoid	RPMI8226	3.9
Haematopoietic and lymphoid	RPMI8402	6.1
Haematopoietic and lymphoid	RS411	4.7
Haematopoietic and lymphoid	SEM	4.5
Haematopoietic and lymphoid	SET2	7.5
Haematopoietic and lymphoid	SIGM5	4.1
Haematopoietic and lymphoid	SKM1	6.1
Haematopoietic and lymphoid	SKMM2	5.1
Haematopoietic and lymphoid	SR786	5.8
Haematopoietic and lymphoid	ST486	5
Haematopoietic and lymphoid	SUDHL10	4.6
Haematopoietic and lymphoid	SUDHL1	4.1
Haematopoietic and lymphoid	SUDHL4	4.7
Haematopoietic and lymphoid	SUDHL5	4.1
Haematopoietic and lymphoid	SUDHL6	4.1
Haematopoietic and lymphoid	SUDHL8	5.5
Haematopoietic and lymphoid	SUPB15	5
Haematopoietic and lymphoid	SUPHD1	3.6
Haematopoietic and lymphoid	SUPM2	6.5
Haematopoietic and lymphoid	SUPT11	7.7
Haematopoietic and lymphoid	SUPT1	5.4
Haematopoietic and lymphoid	TALL1	7.1
Haematopoietic and lymphoid	TF1	5.9
Haematopoietic and lymphoid	THP1	5.6
Haematopoietic and lymphoid	TO175T	6.3
Haematopoietic and lymphoid	TOLEDO	5.1
Haematopoietic and lymphoid	U266B1	4
Haematopoietic and lymphoid	U937	5.8
Haematopoietic and lymphoid	UT7	7.8
Haematopoietic and lymphoid	WSUDLCL2	4.4
Kidney	769P	7
Kidney	786O	5
Kidney	A498	6.4
Kidney	A704	6.4
Kidney	ACHN	5.9
Kidney	BFTC909	4.4
Kidney	CAKI1	7.2
Kidney	CAKI2	5
Kidney	CAL54	7.4
Kidney	KMRC1	5.2
Kidney	KMRC20	7
Kidney	KMRC2	6.7
Kidney	KMRC3	6.5
Kidney	OSRC2	5.9
Kidney	RCC10RGB	6.8
Kidney	SNU1272	7
Kidney	SNU349	7.1
Kidney	TUHR10TKB	6.7
Kidney	TUHR14TKB	7.9
Kidney	TUHR4TKB	7.6
Kidney	VMRCRCW	7.6
Kidney	VMRCRCZ	7.3
Large intestine	C2BBE1	3.6
Large intestine	CCK81	4
Large intestine	CL11	4.7
Large intestine	CL14	4.3
Large intestine	CL34	5
Large intestine	CL40	4.7
Large intestine	COLO205	5.2
Large intestine	COLO320	5.1
Large intestine	COLO678	4.9
Large intestine	CW2	5.3
Large intestine	DLD1	4.4
Large intestine	GP2D	5.5
Large intestine	HCC56	4.5
Large intestine	HCT116	4.6
Large intestine	HCT15	4.2
Large intestine	HS675T	6.7
Large intestine	HS698T	6.4
Large intestine	HT115	4.5
Large intestine	HT29	4.4
Large intestine	HT55	4.7
Large intestine	KM12	4.2
Large intestine	LOVO	4.6
Large intestine	LS1034	4.3
Large intestine	LS123	4.1
Large intestine	LS180	4.7
Large intestine	LS411N	4
Large intestine	LS513	5
Large intestine	MDST8	5.3
Large intestine	NCIH508	5.4
Large intestine	NCIH716	3.9
Large intestine	NCIH747	4.5
Large intestine	OUMS23	5.4
Large intestine	RCM1	4.4
Large intestine	RKO	4.2
Large intestine	SKCO1	4.3
Large intestine	SNU1040	4.5
Large intestine	SNU1197	6.3
Large intestine	SNU175	5.3
Large intestine	SNU283	4.2
Large intestine	SNU407	5.4
Large intestine	SNU503	3.9
Large intestine	SNU61	4
Large intestine	SNU81	6.1
Large intestine	SNUC1	4.4
Large intestine	SNUC2A	6.7
Large intestine	SNUC4	5.2
Large intestine	SNUC5	6.3
Large intestine	SW1116	3.7
Large intestine	SW1417	4.3
Large intestine	SW1463	4.3
Large intestine	SW403	4.2
Large intestine	SW480	4
Large intestine	SW48	5.3
Large intestine	SW620	4
Large intestine	SW837	4.5
Large intestine	SW948	4.9
Large intestine	T84	4.1
Liver	ALEXANDERCELLS	5.3
Liver	C3A	4.7
Liver	HEP3B217	4.8
Liver	HEPG2	4.5
Liver	HLE	4.4
Liver	HLF	4.7
Liver	HUH1	4.2
Liver	HUH6	4.3
Liver	HUH7	5.8
Liver	JHH1	5.1
Liver	JHH2	4.8
Liver	JHH4	4.9
Liver	JHH5	3.8
Liver	JHH6	4.7
Liver	JHH7	3.6
Liver	LI7	4.9
Liver	PLCPRF5	5.4
Liver	SKHEP1	4.2
Liver	SNU182	4.2
Liver	SNU387	5.8
Liver	SNU398	4.2
Liver	SNU423	4.4
Liver	SNU449	6.9
Liver	SNU475	4.9
Liver	SNU761	5.9
Liver	SNU878	4.7
Liver	SNU886	4.8
Lung	A549	4.2
Lung	ABC1	4.6
Lung	BEN	6.9
Lung	CAL12T	4.3
Lung	CALU1	5
Lung	CALU3	4.2
Lung	CALU6	4.2
Lung	CHAGOK1	5.5
Lung	COLO668	6.2
Lung	COLO699	4.3
Lung	CORL105	4.2
Lung	CORL23	4.2
Lung	CORL24	7.3
Lung	CORL279	5.8
Lung	CORL311	7.1
Lung	CORL47	7
Lung	CORL51	7.6
Lung	CORL88	6.3
Lung	CORL95	6
Lung	CPCN	6.2
Lung	DMS114	5.4
Lung	DMS153	6.5
Lung	DMS273	5.1
Lung	DMS454	5.2
Lung	DMS53	4.6
Lung	DMS79	7.6
Lung	DV90	4.2
Lung	EBC1	4.6
Lung	EPLC272H	3.7
Lung	HARA	4.3
Lung	HCC1171	7.2
Lung	HCC1195	4.9
Lung	HCC15	4.2
Lung	HCC2279	5.8
Lung	HCC2935	4.4
Lung	HCC33	6.9
Lung	HCC366	5.9
Lung	HCC4006	4.2
Lung	HCC44	4.4
Lung	HCC78	5.7
Lung	HCC827	4.4
Lung	HCC95	4.4
Lung	HLC1	5.3
Lung	HLFA	5.3
Lung	HS229T	5.3
Lung	HS618T	5.4
Lung	IALM	4.5
Lung	KNS62	4.3
Lung	LC1F	5.7
Lung	LC1SQSF	5.5
Lung	LCLC103H	4.1
Lung	LCLC97TM1	6
Lung	LK2	4.9
Lung	LOUNH91	5.2
Lung	LU65	5
Lung	LU99	4.6
Lung	LUDLU1	4.7
Lung	LXF289	5.8
Lung	MORCPR	4.8
Lung	NCIH1048	7.1
Lung	NCIH1092	7.3
Lung	NCIH1105	6.4
Lung	NCIH1155	5.5
Lung	NCIH1184	6.4
Lung	NCIH1299	5.4
Lung	NCIH1339	6.1
Lung	NCIH1341	4.5
Lung	NCIH1355	4.5
Lung	NCIH1373	5.5
Lung	NCIH1385	4.7
Lung	NCIH1395	4.3
Lung	NCIH1435	4.7
Lung	NCIH1436	6.3
Lung	NCIH1437	4.1
Lung	NCIH146	6.1
Lung	NCIH1563	6.1
Lung	NCIH1568	4.3
Lung	NCIH1573	6.2
Lung	NCIH1581	4.9
Lung	NCIH1618	7.2
Lung	NCIH1623	5.3
Lung	NCIH1648	4.6
Lung	NCIH1650	4.5
Lung	NCIH1651	4.7
Lung	NCIH1666	5.6
Lung	NCIH1693	5.3
Lung	NCIH1694	7.1
Lung	NCIH1703	6.6
Lung	NCIH1734	5.5
Lung	NCIH1755	5.6
Lung	NCIH1781	5.8
Lung	NCIH1792	4.2
Lung	NCIH1793	4.4
Lung	NCIH1836	7.4
Lung	NCIH1838	4.3
Lung	NCIH1869	4.4
Lung	NCIH1876	7.5
Lung	NCIH1915	4.8
Lung	NCIH1930	5.9
Lung	NCIH1944	3.9
Lung	NCIH1963	7.3
Lung	NCIH196	6.4
Lung	NCIH1975	4.2
Lung	NCIH2009	5.2
Lung	NCIH2023	4.9
Lung	NCIH2029	6
Lung	NCIH2030	5
Lung	NCIH2066	5.1
Lung	NCIH2081	7.4
Lung	NCIH2085	4.9
Lung	NCIH2087	4.6
Lung	NCIH209	6.6
Lung	NCIH2106	5.9
Lung	NCIH2110	4.4
Lung	NCIH211	6.1
Lung	NCIH2122	4.6
Lung	NCIH2126	4.7
Lung	NCIH2141	6.4
Lung	NCIH2170	4.3
Lung	NCIH2171	4.3
Lung	NCIH2172	4.3
Lung	NCIH2196	5.6
Lung	NCIH2227	6.4
Lung	NCIH2228	6.1
Lung	NCIH226	5.1
Lung	NCIH2286	5.2
Lung	NCIH2291	4.3
Lung	NCIH2342	4.9
Lung	NCIH2347	4.6
Lung	NCIH23	4.8
Lung	NCIH2405	4.2
Lung	NCIH2444	5.4
Lung	NCIH292	4.3
Lung	NCIH322	4.4
Lung	NCIH3255	5.2
Lung	NCIH358	6.5
Lung	NCIH441	5
Lung	NCIH446	5.2
Lung	NCIH460	4.1
Lung	NCIH510	5
Lung	NCIH520	4.5
Lung	NCIH522	5.9
Lung	NCIH524	5
Lung	NCIH526	5.6
Lung	NCIH596	6.2
Lung	NCIH647	5.6
Lung	NCIH650	5.1
Lung	NCIH661	4.8
Lung	NCIH69	4.6
Lung	NCIH727	4.6
Lung	NCIH810	5.9
Lung	NCIH82	5.3
Lung	NCIH838	4.9
Lung	NCIH841	5.4
Lung	NCIH854	5.6
Lung	NCIH889	5.3
Lung	PC14	4.6
Lung	RERFLCAD1	5.5
Lung	RERFLCAD2	4.5
Lung	RERFLCAI	4.6
Lung	RERFLCKJ	4.8
Lung	RERFLCMS	5.7
Lung	RERFLCSQ1	5.1
Lung	SBC5	6.6
Lung	SCLC21H	6.3
Lung	SHP77	4.5
Lung	SKLU1	5
Lung	SKMES1	5.6
Lung	SQ1	4.5
Lung	SW1271	5.7
Lung	SW1573	4.6
Lung	SW900	5.5
Lung	VMRCLCD	4.7
Lung	VMRCLCP	4.1
Oesophagus	COLO680N	4.6
Oesophagus	ECGI10	6.4
Oesophagus	KYSE140	4.5
Oesophagus	KYSE150	3.9
Oesophagus	KYSE180	4.5
Oesophagus	KYSE270	4.1
Oesophagus	KYSE30	6.1
Oesophagus	KYSE410	4.4
Oesophagus	KYSE450	4.4
Oesophagus	KYSE510	4.3
Oesophagus	KYSE520	4.8
Oesophagus	KYSE70	4.3
Oesophagus	OE19	5.6
Oesophagus	OE33	3.9
Oesophagus	TE10	4.4
Oesophagus	TE11	4.1
Oesophagus	TE14	4.7
Oesophagus	TE15	4.9
Oesophagus	TE1	4.8
Oesophagus	TE4	4.7
Oesophagus	TE5	4
Oesophagus	TE6	4.2
Oesophagus	TE8	5.8
Oesophagus	TE9	5
Oesophagus	TT	5
Ovary	59M	5.9
Ovary	A2780	5.5
Ovary	CAOV3	4.4
Ovary	CAOV4	6.4
Ovary	COLO704	6.2
Ovary	COV318	5.9
Ovary	COV362	5.1
Ovary	COV434	5.7
Ovary	COV504	6.3
Ovary	COV644	4.9
Ovary	EFO21	5.7
Ovary	EFO27	4.5
Ovary	ES2	4.7
Ovary	FUOV1	4.2
Ovary	HEYA8	4.3
Ovary	HS571T	6.7
Ovary	IGROV1	5.8
Ovary	JHOC5	4.5
Ovary	JHOM1	5.1
Ovary	JHOM2B	4.6
Ovary	JHOS2	5.7
Ovary	JHOS4	5.3
Ovary	KURAMOCHI	7
Ovary	MCAS	4.9
Ovary	NIHOVCAR3	5.2
Ovary	OAW28	5.2
Ovary	OAW42	6.2
Ovary	OC314	5.5
Ovary	OC316	5.4
Ovary	ONCODG1	5.2
Ovary	OV56	6.4
Ovary	OV7	5.4
Ovary	OV90	4.4
Ovary	OVCAR4	5.3
Ovary	OVCAR8	5.3
Ovary	OVISE	5.4
Ovary	OVK18	6.3
Ovary	OVKATE	6.7
Ovary	OVMANA	6.4
Ovary	OVSAHO	5.1
Ovary	OVTOKO	4.9
Ovary	RMGI	4.8
Ovary	RMUGS	5.5
Ovary	SKOV3	5.8
Ovary	SNU119	7.7
Ovary	SNU840	4.3
Ovary	SNU8	5.3
Ovary	TOV112D	5.1
Ovary	TOV21G	6.9
Ovary	TYKNU	5.1
Pancreas	ASPC1	5.1
Pancreas	BXPC3	4.7
Pancreas	CAPAN1	4
Pancreas	CAPAN2	5.4
Pancreas	CFPAC1	4.7
Pancreas	DANG	4.1
Pancreas	HPAC	6.1
Pancreas	HPAFII	4.8
Pancreas	HS766T	5
Pancreas	HUPT3	5.3
Pancreas	HUPT4	4.5
Pancreas	KCIMOH1	6
Pancreas	KLM1	4.5
Pancreas	KP2	6.4
Pancreas	KP3	5.5
Pancreas	KP4	4.8
Pancreas	L33	4.4
Pancreas	MIAPACA2	4.8
Pancreas	PANC0203	5.4
Pancreas	PANC0213	5.9
Pancreas	PANC0327	4.8
Pancreas	PANC0403	5.1
Pancreas	PANC0504	5.6
Pancreas	PANC0813	4.3
Pancreas	PANC1005	4.6
Pancreas	PANC1	4.2
Pancreas	PATU8902	4.7
Pancreas	PATU8988S	4.2
Pancreas	PATU8988T	3.9
Pancreas	PK1	4.2
Pancreas	PK45H	5.3
Pancreas	PK59	4.2
Pancreas	PL45	5.8
Pancreas	PSN1	4.1
Pancreas	QGP1	7
Pancreas	SNU213	6.6
Pancreas	SNU324	6.9
Pancreas	SNU410	4.5
Pancreas	SU8686	6.1
Pancreas	SUIT2	5.6
Pancreas	SW1990	4.4
Pancreas	T3M4	5
Pancreas	TCCPAN2	4.3
Pancreas	YAPC	5.5
Pleura	ACCMESO1	4.8
Pleura	DM3	6.3
Pleura	ISTMES1	3.8
Pleura	ISTMES2	4.8
Pleura	JL1	6
Pleura	MPP89	4.3
Pleura	MSTO211H	5
Pleura	NCIH2052	4.3
Pleura	NCIH2452	6.5
Pleura	NCIH28	7.6
Prostate	22RV1	5.1
Prostate	DU145	5.3
Prostate	LNCAPCLONEFGC	4.9
Prostate	MDAPCA2B	5.5
Prostate	NCIH660	5
Prostate	PC3	5
Prostate	VCAP	4.4
Salivary gland	A253	4
Salivary gland	YD15	4.4
Skin	A101D	5.6
Skin	A2058	5.3
Skin	A375	3.8
Skin	C32	5.5
Skin	CHL1	5.8
Skin	CJM	5.1
Skin	COLO679	5.4
Skin	COLO741	3.9
Skin	COLO783	4.9
Skin	COLO792	4.4
Skin	COLO800	4.4
Skin	COLO818	4.8
Skin	COLO829	5.7
Skin	COLO849	5.2
Skin	G361	4.4
Skin	GRM	4.2
Skin	HMCB	6.7
Skin	HS294T	5.4
Skin	HS600T	6.5
Skin	HS688AT	6.2
Skin	HS695T	5.2
Skin	HS839T	5.8
Skin	HS852T	5.6
Skin	HS895T	6.4
Skin	HS934T	5
Skin	HS936T	5.1
Skin	HS939T	6
Skin	HS940T	6.2
Skin	HS944T	5
Skin	HT144	4.2
Skin	IGR1	4.6
Skin	IGR37	4.1
Skin	IGR39	4
Skin	IPC298	4.7
Skin	K029AX	4.3
Skin	LOXIMVI	4.8
Skin	MALME3M	5.1
Skin	MDAMB435S	4.4
Skin	MELHO	3.9
Skin	MELJUSO	4.5
Skin	MEWO	4.2
Skin	RPMI7951	5.3
Skin	RVH421	4.1
Skin	SH4	4.5
Skin	SKMEL1	4.8
Skin	SKMEL24	5.7
Skin	SKMEL28	4.1
Skin	SKMEL2	4.5
Skin	SKMEL30	4.5
Skin	SKMEL31	6.9
Skin	SKMEL3	3.8
Skin	SKMEL5	3.9
Skin	UACC257	4
Skin	UACC62	4.7
Skin	WM115	7.1
Skin	WM1799	4.6
Skin	WM2664	5.4
Skin	WM793	6.2
Skin	WM88	4.9
Skin	WM983B	5.2
Small intestine	HUTU80	6.3
Soft tissue	A204	5.1
Soft tissue	G401	5.5
Soft tissue	G402	6
Soft tissue	GCT	4.8
Soft tissue	HS729	6.3
Soft tissue	HT1080	4.9
Soft tissue	KYM1	5.2
Soft tissue	MESSA	5.5
Soft tissue	RD	5.2
Soft tissue	RH30	4.2
Soft tissue	RH41	5.2
Soft tissue	RKN	5.1
Soft tissue	S117	5.3
Soft tissue	SJRH30	5.4
Soft tissue	SKLMS1	6.2
Soft tissue	SKUT1	4.2
Soft tissue	TE125T	5.7
Soft tissue	TE159T	6.5
Soft tissue	TE441T	4.4
Soft tissue	TE617T	5.6
Stomach	2313287	4.1
Stomach	AGS	4.3
Stomach	AZ521	4.5
Stomach	ECC10	6.6
Stomach	ECC12	6.8
Stomach	FU97	4.4
Stomach	GCIY	5.8
Stomach	GSS	5.4
Stomach	GSU	4.7
Stomach	HGC27	5.5
Stomach	HS746T	5
Stomach	HUG1N	4.6
Stomach	IM95	4.7
Stomach	KATOIII	4.2
Stomach	KE39	4.5
Stomach	LMSU	4.4
Stomach	MKN1	4.9
Stomach	MKN45	4
Stomach	MKN74	7.6
Stomach	MKN7	4.3
Stomach	NCCSTCK140	4.6
Stomach	NCIN87	5
Stomach	NUGC2	5.3
Stomach	NUGC3	4.5
Stomach	NUGC4	7.5
Stomach	OCUM1	3.9
Stomach	RERFGC1B	4.6
Stomach	SH10TC	4.2
Stomach	SNU16	3.9
Stomach	SNU1	4.8
Stomach	SNU216	4.7
Stomach	SNU520	7.1
Stomach	SNU5	3.7
Stomach	SNU601	4.1
Stomach	SNU620	4
Stomach	SNU668	4.2
Stomach	SNU719	3.9
Stomach	TGBC11TKB	5.2
Thyroid	8305C	5.7
Thyroid	8505C	4.1
Thyroid	BCPAP	5.9
Thyroid	BHT101	5.9
Thyroid	CAL62	5.5
Thyroid	CGTHW1	6.8
Thyroid	FTC133	5.8
Thyroid	FTC238	4.7
Thyroid	ML1	6.8
Thyroid	SW579	5.6
Thyroid	TT2609C02	4.6
Thyroid	TT	6.5
Upper aerodigestive tract	BHY	4
Upper aerodigestive tract	BICR16	4.3
Upper aerodigestive tract	BICR18	5
Upper aerodigestive tract	BICR22	5.3
Upper aerodigestive tract	BICR31	5
Upper aerodigestive tract	BICR56	6
Upper aerodigestive tract	BICR6	4.5
Upper aerodigestive tract	CAL27	4.1
Upper aerodigestive tract	CAL33	4.5
Upper aerodigestive tract	DETROIT562	4.3
Upper aerodigestive tract	FADU	4.1
Upper aerodigestive tract	HS840T	5.5
Upper aerodigestive tract	HSC2	4.3
Upper aerodigestive tract	HSC3	4.5
Upper aerodigestive tract	HSC4	4.3
Upper aerodigestive tract	PECAPJ15	4.3
Upper aerodigestive tract	PECAPJ34CLONEC12	4
Upper aerodigestive tract	PECAPJ41CLONED2	5.4
Upper aerodigestive tract	PECAPJ49	4.4
Upper aerodigestive tract	SCC15	4.5
Upper aerodigestive tract	SCC25	4.1
Upper aerodigestive tract	SCC4	4.8
Upper aerodigestive tract	SCC9	4.7
Upper aerodigestive tract	SNU1076	5.3
Upper aerodigestive tract	SNU1214	4.9
Upper aerodigestive tract	SNU46	4.9
Upper aerodigestive tract	SNU899	4.6
Upper aerodigestive tract	YD10B	4.2
Upper aerodigestive tract	YD38	4.2
Upper aerodigestive tract	YD8	5.8
Urinary tract	5637	4.1
Urinary tract	639V	4.2
Urinary tract	647V	4.4
Urinary tract	BC3C	4
Urinary tract	BFTC905	3.8
Urinary tract	CAL29	4
Urinary tract	HS172T	6.1
Urinary tract	HT1197	4
Urinary tract	HT1376	4.3
Urinary tract	J82	4.1
Urinary tract	JMSU1	6.2
Urinary tract	KMBC2	5.2
Urinary tract	KU1919	5.1
Urinary tract	RT11284	4.4
Urinary tract	RT112	4.4
Urinary tract	RT4	5.7
Urinary tract	SCABER	4.2
Urinary tract	SW1710	7.6
Urinary tract	SW780	4.3
Urinary tract	T24	4.5
Urinary tract	TCCSUP	4.9
Urinary tract	UMUC1	4.3
Urinary tract	UMUC3	4
Urinary tract	VMCUB1	5.1

> The Human Protein Atlas (HPA)

Tissue	Expression Level (TPM)
Adipose tissue	3.1
Adrenal gland	4.6
Appendix	3.6
Bone marrow	1.3
Breast	3.7
Cerebral cortex	7.3
Cervix, uterine	6.6
Colon	2.5
Duodenum	2.4
Endometrium	6.4
Epididymis	3.2
Esophagus	3.4
Fallopian tube	4.8
Gallbladder	6.9
Heart muscle	2.2
Kidney	4.9
Liver	1.1
Lung	4
Lymph node	3.4
Ovary	5.8
Pancreas	0.4
Parathyroid gland	12
Placenta	4.9
Prostate	6.2
Rectum	2.9
Salivary gland	1
Seminal vesicle	4.8
Skeletal muscle	1
Skin	2.7
Small intestine	2.1
Smooth muscle	5.7
Spleen	4.8
Stomach	2.2
Testis	6.9
Thyroid gland	6.8
Tonsil	2.6
Urinary bladder	4.2

> Text Mining based Expression

PMID	Expression	Cancer	Evidence
19603017	Overexpression	Ovarian Carcinoma	Our results suggest that the overexpression of uPA, CD44 and MRD1 is correlated with EOC progression; both uPA and CD44 are related with drug resistance during EOC metastasis and could be useful therapeutically.
26137238	Overexpression	Acute Lymphoblastic Leukemia	The high level expression of BAALC had a significant association with the pre-B-ALL subtype, leukocytosis and positive MRD after one year of treatment in leukemic patients. In addition, a positive correlation between BAALC and MDR1 mRNA expression was shown in this group.

Summary
Symbol	MBD5
Name	methyl-CpG binding domain protein 5
Aliases	FLJ11113; KIAA1461; MRD1; methyl-CpG-binding protein MBD5; Methyl-CpG-binding domain protein 5
Location	2q23.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.221	7e-06	28.5	59.9	11.6	Neutral
BRCA	Breast invasive carcinoma	1075	0.179	3.48e-09	24.5	67.9	7.6	Neutral
CESC	Cervical and endocervical cancers	292	0.181	0.00191	16.1	71.9	12	Neutral
COAD	Colon adenocarcinoma	449	0.305	3.93e-11	5.3	77.1	17.6	Neutral
ESCA	Esophageal carcinoma	183	0.188	0.0108	14.2	59	26.8	Neutral
GBM	Glioblastoma multiforme	147	0.195	0.0181	6.1	87.1	6.8	Neutral
HNSC	Head and Neck squamous cell carcinoma	514	0.121	0.00616	10.7	73.9	15.4	Neutral
KIRC	Kidney renal clear cell carcinoma	525	0.327	1.43e-14	2.9	81.9	15.2	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	0.217	0.000202	2.4	81.2	16.3	Neutral
LAML	Acute Myeloid Leukemia	166	0.147	0.0581	0	100	0	Neutral
LGG	Brain Lower Grade Glioma	513	0.091	0.0399	4.5	93	2.5	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.261	4.39e-07	18.7	70.6	10.7	Neutral
LUAD	Lung adenocarcinoma	512	0.214	1.04e-06	7.2	64.1	28.7	Neutral
LUSC	Lung squamous cell carcinoma	498	0.16	0.000329	13.3	58.8	27.9	Neutral
OV	Ovarian serous cystadenocarcinoma	300	0.53	3.77e-23	18.7	49	32.3	Neutral
PAAD	Pancreatic adenocarcinoma	177	0.154	0.0403	7.3	81.4	11.3	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	0.225	0.004	8	90.7	1.2	Neutral
PRAD	Prostate adenocarcinoma	491	0.43	1.65e-23	17.1	81.7	1.2	Neutral
READ	Rectum adenocarcinoma	164	0.244	0.00163	4.9	70.7	24.4	Neutral
SARC	Sarcoma	255	0.289	2.7e-06	25.9	60.4	13.7	Neutral
SKCM	Skin Cutaneous Melanoma	367	0.336	4.18e-11	13.9	65.1	21	Neutral
STAD	Stomach adenocarcinoma	413	0.135	0.00583	13.3	70.9	15.7	Neutral
TGCT	Testicular Germ Cell Tumors	150	0.096	0.242	6	66.7	27.3	Neutral
THCA	Thyroid carcinoma	497	0.125	0.00537	2	97.8	0.2	Neutral
THYM	Thymoma	119	0.213	0.0201	2.5	97.5	0	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.308	3.1e-13	3.9	80.3	15.8	Neutral

Summary
Symbol	MBD5
Name	methyl-CpG binding domain protein 5
Aliases	FLJ11113; KIAA1461; MRD1; methyl-CpG-binding protein MBD5; Methyl-CpG-binding domain protein 5
Location	2q23.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	0.248	2.34e-07	17	408	-0.016	8.23e-09	NS/NA
BRCA	Breast invasive carcinoma	0.188	2.6e-08	83	785	-0.007	1.57e-09	NS/NA
CESC	Cervical and endocervical cancers	0.095	0.0944	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	0.135	0.0165	19	297	-0.003	0.000249	NS/NA
ESCA	Esophageal carcinoma	0.059	0.411	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.015	0.906	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	0.129	0.00266	20	522	-0.009	1.65e-12	NS/NA
KIRC	Kidney renal clear cell carcinoma	0.099	0.0668	24	319	-0.004	0.00925	NS/NA
KIRP	Kidney renal papillary cell carcinoma	0.177	0.00225	23	275	-0.009	0.00952	NS/NA
LAML	Acute Myeloid Leukemia	-0.077	0.318	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	0.145	0.000818	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	0.256	1.44e-07	41	373	-0.14	1.96e-47	NS/NA
LUAD	Lung adenocarcinoma	0.1	0.0288	21	456	-0.003	0.0655	NS/NA
LUSC	Lung squamous cell carcinoma	0.088	0.0874	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	-0.033	0.948	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	0.174	0.0183	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.038	0.601	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	0.14	0.00117	35	498	-0.012	5.98e-07	NS/NA
READ	Rectum adenocarcinoma	0.192	0.0548	2	99	NA	NA	NS/NA
SARC	Sarcoma	0.241	8.48e-05	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	0.128	0.0054	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	0.047	0.365	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	0.287	0.00029	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.062	0.145	50	509	0.002	0.31	NS/NA
THYM	Thymoma	-0.014	0.878	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.065	0.159	34	431	-0.004	0.0293	NS/NA

Summary
Symbol	MBD5
Name	methyl-CpG binding domain protein 5
Aliases	FLJ11113; KIAA1461; MRD1; methyl-CpG-binding protein MBD5; Methyl-CpG-binding domain protein 5
Location	2q23.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA) [ TOP ]
There is no antibody staining data.

Summary
Symbol	MBD5
Name	methyl-CpG binding domain protein 5
Aliases	FLJ11113; KIAA1461; MRD1; methyl-CpG-binding protein MBD5; Methyl-CpG-binding domain protein 5
Location	2q23.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.0532	NS	24476821
BRCA	Breast invasive carcinoma	521	3.18e-12	Significant	23000897
COAD	Colon adenocarcinoma	149	0.0274	Significant	22810696
GBM	Glioblastoma multiforme	157	0.0451	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	0.000531	Significant	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.215	NS	26536169
LGG	Brain Lower Grade Glioma	513	1.64e-14	Significant	26824661
LUAD	Lung adenocarcinoma	230	0.121	NS	25079552
LUSC	Lung squamous cell carcinoma	178	0.0227	Significant	22960745
OV	Ovarian serous cystadenocarcinoma	287	0.731	NS	21720365
PRAD	Prostate adenocarcinoma	333	3.12e-12	Significant	26544944
READ	Rectum adenocarcinoma	67	0.464	NS	22810696
SKCM	Skin Cutaneous Melanoma	315	0.0144	Significant	26091043
STAD	Stomach adenocarcinoma	277	0.00169	Significant	25079317
THCA	Thyroid carcinoma	391	0.346	NS	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	0.00751	Significant	23636398

> Overall survival

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	0.734	0.139	NS
BRCA	Breast invasive carcinoma	1079	1.643	0.0338	Shorter
CESC	Cervical and endocervical cancers	291	2.131	0.0336	Shorter
COAD	Colon adenocarcinoma	439	1.611	0.0957	NS
ESCA	Esophageal carcinoma	184	0.91	0.772	NS
GBM	Glioblastoma multiforme	158	0.879	0.6	NS
HNSC	Head and Neck squamous cell carcinoma	518	1.07	0.722	NS
KIRC	Kidney renal clear cell carcinoma	531	0.43	5.2e-05	Longer
KIRP	Kidney renal papillary cell carcinoma	287	1.1	0.803	NS
LAML	Acute Myeloid Leukemia	149	0.978	0.96	NS
LGG	Brain Lower Grade Glioma	511	0.403	0.000278	Longer
LIHC	Liver hepatocellular carcinoma	365	1.12	0.641	NS
LUAD	Lung adenocarcinoma	502	1.098	0.645	NS
LUSC	Lung squamous cell carcinoma	494	1.251	0.266	NS
OV	Ovarian serous cystadenocarcinoma	303	1.338	0.159	NS
PAAD	Pancreatic adenocarcinoma	177	0.902	0.71	NS
PCPG	Pheochromocytoma and Paraganglioma	179	1.823	0.619	NS
PRAD	Prostate adenocarcinoma	497	0.424	0.449	NS
READ	Rectum adenocarcinoma	159	1.573	0.454	NS
SARC	Sarcoma	259	0.808	0.435	NS
SKCM	Skin Cutaneous Melanoma	459	0.65	0.0194	Longer
STAD	Stomach adenocarcinoma	388	1.41	0.12	NS
TGCT	Testicular Germ Cell Tumors	134	0	0.317	NS
THCA	Thyroid carcinoma	500	2.664	0.213	NS
THYM	Thymoma	119	1.165	0.852	NS
UCEC	Uterine Corpus Endometrial Carcinoma	543	2.164	0.00866	Shorter

> Stage

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	-0.048	0.339	NS
BRCA	Breast invasive carcinoma	1071	-0.055	0.0737	NS
CESC	Cervical and endocervical cancers	167	-0.06	0.441	NS
COAD	Colon adenocarcinoma	445	0.09	0.0576	NS
ESCA	Esophageal carcinoma	162	-0.034	0.667	NS
HNSC	Head and Neck squamous cell carcinoma	448	0.07	0.137	NS
KIRC	Kidney renal clear cell carcinoma	531	-0.154	0.000373	Lower
KIRP	Kidney renal papillary cell carcinoma	260	-0.05	0.42	NS
LIHC	Liver hepatocellular carcinoma	347	0.107	0.0462	Higher
LUAD	Lung adenocarcinoma	507	0.048	0.282	NS
LUSC	Lung squamous cell carcinoma	497	-0.082	0.0686	NS
OV	Ovarian serous cystadenocarcinoma	302	0.009	0.87	NS
PAAD	Pancreatic adenocarcinoma	176	-0.037	0.628	NS
READ	Rectum adenocarcinoma	156	0.151	0.0601	NS
SKCM	Skin Cutaneous Melanoma	410	-0.068	0.167	NS
STAD	Stomach adenocarcinoma	392	0.067	0.185	NS
TGCT	Testicular Germ Cell Tumors	81	-0.057	0.612	NS
THCA	Thyroid carcinoma	499	0.001	0.985	NS
UCEC	Uterine Corpus Endometrial Carcinoma	501	0.039	0.388	NS

> Grade

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	0.027	0.659	NS
HNSC	Head and Neck squamous cell carcinoma	498	0.103	0.0212	Higher
KIRC	Kidney renal clear cell carcinoma	525	-0.171	7.95e-05	Lower
LGG	Brain Lower Grade Glioma	514	-0.134	0.00226	Lower
LIHC	Liver hepatocellular carcinoma	366	-0.005	0.925	NS
OV	Ovarian serous cystadenocarcinoma	296	-0.046	0.433	NS
PAAD	Pancreatic adenocarcinoma	176	-0.067	0.374	NS
STAD	Stomach adenocarcinoma	406	0.006	0.908	NS
UCEC	Uterine Corpus Endometrial Carcinoma	534	0.119	0.00604	Higher

Summary
Symbol	MBD5
Name	methyl-CpG binding domain protein 5
Aliases	FLJ11113; KIAA1461; MRD1; methyl-CpG-binding protein MBD5; Methyl-CpG-binding domain protein 5
Location	2q23.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	MBD5
Name	methyl-CpG binding domain protein 5
Aliases	FLJ11113; KIAA1461; MRD1; methyl-CpG-binding protein MBD5; Methyl-CpG-binding domain protein 5
Location	2q23.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for MBD5.

Summary
Symbol	MBD5
Name	methyl-CpG binding domain protein 5
Aliases	FLJ11113; KIAA1461; MRD1; methyl-CpG-binding protein MBD5; Methyl-CpG-binding domain protein 5
Location	2q23.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining

PMID	Cancer	Hierarchy	Gene	Relation to CR	Evidence
26137238	Acute Lymphoblastic Leukemia	partner	BAALC	positive correlation	In addition, a positive correlation between BAALC and MDR1 mRNA expression was shown in this group.