CR2Cancer

Summary
Symbol	MGA
Name	MGA, MAX dimerization protein
Aliases	KIAA0518; MAD5; MXD5; FLJ12634; MAX gene associated; MAX dimerization protein 5; MAX gene-associated protein
Location	15q15
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

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Domain

PF16059 Domain of unknown function (DUF4801)
PF00010 Helix-loop-helix DNA-binding domain
PF00907 T-box

Function

Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor (By similarity).

Classification

Class	Modification	Substrate	Product	PubMed
Histone modification write cofactor, Histone modification write cofactor	Histone methylation, Histone acetylation	DNA motif	#	#

> Gene Ontology [ TOP ]
Biological Process	-
Molecular Function	-
Cellular Component	GO:0034708 methyltransferase complex GO:0035097 histone methyltransferase complex GO:0044665 MLL1/2 complex GO:0071339 MLL1 complex

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	-

Summary
Symbol	MGA
Name	MGA, MAX dimerization protein
Aliases	KIAA0518; MAD5; MXD5; FLJ12634; MAX gene associated; MAX dimerization protein 5; MAX gene-associated protein
Location	15q15
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM4552407	c.558G>A	p.L186L	Substitution - coding silent	Skin
COSM1372837	c.7871_7872insA	p.D2627fs*45	Insertion - Frameshift	Large_intestine
COSM1662755	c.3439G>T	p.E1147*	Substitution - Nonsense	Kidney
COSM3420289	c.2422G>T	p.E808*	Substitution - Nonsense	Large_intestine
COSM1301113	c.400C>T	p.R134C	Substitution - Missense	Urinary_tract
COSM1372839	c.8728C>T	p.R2910W	Substitution - Missense	Large_intestine
COSM3816034	c.7531C>G	p.L2511V	Substitution - Missense	Breast
COSM961517	c.4415G>T	p.S1472I	Substitution - Missense	Endometrium
COSM5362855	c.2678C>A	p.P893H	Substitution - Missense	Large_intestine
COSM5621254	c.7840A>G	p.N2614D	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM961502	c.2596C>T	p.R866*	Substitution - Nonsense	Endometrium
COSM4826036	c.2422G>C	p.E808Q	Substitution - Missense	Cervix
COSM4054555	c.877C>A	p.R293S	Substitution - Missense	Stomach
COSM3956617	c.3589A>G	p.T1197A	Substitution - Missense	Lung
COSM266928	c.1881A>G	p.R627R	Substitution - coding silent	Large_intestine
COSM118435	c.3684C>G	p.V1228V	Substitution - coding silent	Ovary
COSM433837	c.7681A>G	p.K2561E	Substitution - Missense	Breast
COSM5986541	c.3523_3524insT	p.P1175fs*7	Insertion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM3501115	c.8161C>T	p.P2721S	Substitution - Missense	Skin
COSM4054554	c.196C>T	p.L66F	Substitution - Missense	Stomach
COSM1215013	c.4340G>A	p.G1447D	Substitution - Missense	Large_intestine
COSM3981494	c.3200A>T	p.Q1067L	Substitution - Missense	Ovary
COSM3749297	c.3451G>A	p.E1151K	Substitution - Missense	Large_intestine
COSM3711694	c.1110G>T	p.P370P	Substitution - coding silent	Upper_aerodigestive_tract
COSM5368593	c.155G>T	p.S52I	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5740297	c.4588T>A	p.S1530T	Substitution - Missense	Small_intestine
COSM3501111	c.7535T>A	p.I2512N	Substitution - Missense	Skin
COSM5667465	c.7216G>T	p.E2406*	Substitution - Nonsense	Soft_tissue
COSM3501119	c.9171C>T	p.L3057L	Substitution - coding silent	Skin
COSM5893829	c.926C>T	p.P309L	Substitution - Missense	Skin
COSM5367861	c.7726_7727insA	p.R2578fs*9	Insertion - Frameshift	Large_intestine
COSM5574753	c.6132_6136delGTCAG	p.S2045fs*7	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM700638	c.4193C>T	p.S1398F	Substitution - Missense	Lung
COSM5383266	c.1154C>T	p.P385L	Substitution - Missense	Skin
COSM1562942	c.2742T>G	p.S914S	Substitution - coding silent	Large_intestine
COSM355055	c.2515G>T	p.E839*	Substitution - Nonsense	Lung
COSM1372818	c.1836delA	p.R614fs*7	Deletion - Frameshift	Large_intestine
COSM3711694	c.1110G>T	p.P370P	Substitution - coding silent	Upper_aerodigestive_tract
COSM5416096	c.2689A>T	p.K897*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM1629540	c.6396T>C	p.V2132V	Substitution - coding silent	Liver
COSM3501109	c.6325C>T	p.Q2109*	Substitution - Nonsense	Skin
COSM961519	c.4878C>T	p.V1626V	Substitution - coding silent	Skin
COSM2270795	c.2686C>T	p.R896*	Substitution - Nonsense	Prostate
COSM4578218	c.5956A>T	p.I1986F	Substitution - Missense	Bone
COSM3886947	c.4265C>T	p.S1422F	Substitution - Missense	Skin
COSM71632	c.5905A>G	p.T1969A	Substitution - Missense	Ovary
COSM5383268	c.5810C>T	p.S1937F	Substitution - Missense	Skin
COSM5810830	c.1312G>T	p.A438S	Substitution - Missense	Liver
COSM4391632	c.8080T>G	p.L2694V	Substitution - Missense	Breast
COSM1188971	c.6175C>A	p.Q2059K	Substitution - Missense	Lung
COSM433838	c.8016C>G	p.L2672L	Substitution - coding silent	Breast
COSM1286176	c.9202G>T	p.A3068S	Substitution - Missense	Autonomic_ganglia
COSM433833	c.4621C>T	p.R1541C	Substitution - Missense	Central_nervous_system
COSM3501097	c.925C>T	p.P309S	Substitution - Missense	Skin
COSM470615	c.5174C>G	p.P1725R	Substitution - Missense	Kidney
COSM5454345	c.7928C>T	p.A2643V	Substitution - Missense	Large_intestine
COSM4768294	c.112C>G	p.Q38E	Substitution - Missense	Biliary_tract
COSM4054567	c.5174C>T	p.P1725L	Substitution - Missense	Stomach
COSM4408043	c.4106T>C	p.V1369A	Substitution - Missense	Oesophagus
COSM1242507	c.7407G>A	p.A2469A	Substitution - coding silent	Oesophagus
COSM3816026	c.424T>G	p.W142G	Substitution - Missense	Breast
COSM4502813	c.6377C>T	p.S2126F	Substitution - Missense	Skin
COSM282783	c.822G>T	p.K274N	Substitution - Missense	Large_intestine
COSM4829025	c.2125G>A	p.E709K	Substitution - Missense	Cervix
COSM1372836	c.7621C>T	p.R2541W	Substitution - Missense	Large_intestine
COSM2270906	c.7334G>A	p.R2445Q	Substitution - Missense	Pancreas
COSM4054569	c.5520T>C	p.P1840P	Substitution - coding silent	Stomach
COSM1608354	c.894G>A	p.Q298Q	Substitution - coding silent	Liver
COSM5716498	c.7511C>T	p.S2504F	Substitution - Missense	Skin
COSM4747068	c.7727delA	p.R2578fs*28	Deletion - Frameshift	Stomach
COSM4449445	c.2321-1G>A	p.?	Unknown	Skin
COSM2270837	c.4350G>A	p.L1450L	Substitution - coding silent	Upper_aerodigestive_tract
COSM5882568	c.478C>T	p.P160S	Substitution - Missense	Skin
COSM3816031	c.5924C>A	p.S1975*	Substitution - Nonsense	Breast
COSM3886948	c.8749C>T	p.P2917S	Substitution - Missense	Skin
COSM5574750	c.3224_3240del17	p.C1076fs*10	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM5705861	c.7650_7653delTCTT	p.L2551fs*9	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM5982809	c.4311G>A	p.L1437L	Substitution - coding silent	Upper_aerodigestive_tract
COSM961505	c.2860delT	p.F954fs*40	Deletion - Frameshift	Endometrium
COSM4607149	c.7615C>T	p.R2539*	Substitution - Nonsense	Skin
COSM302638	c.8907C>T	p.A2969A	Substitution - coding silent	Central_nervous_system
COSM4927653	c.603G>A	p.L201L	Substitution - coding silent	Liver
COSM1215014	c.7333C>T	p.R2445*	Substitution - Nonsense	Large_intestine
COSM961512	c.4010A>G	p.E1337G	Substitution - Missense	Endometrium
COSM3816033	c.7191G>A	p.E2397E	Substitution - coding silent	Breast
COSM5417712	c.3797delA	p.Q1266fs*25	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM961523	c.5877A>G	p.Q1959Q	Substitution - coding silent	Endometrium
COSM25669	c.3796C>T	p.Q1266*	Substitution - Nonsense	Kidney
COSM3706558	c.4435-3C>T	p.?	Unknown	Liver
COSM2270855	c.5062G>A	p.E1688K	Substitution - Missense	Large_intestine
COSM4390372	c.2738C>T	p.S913L	Substitution - Missense	Urinary_tract
COSM4557186	c.7329G>A	p.R2443R	Substitution - coding silent	Skin
COSM4981330	c.3568C>T	p.Q1190*	Substitution - Nonsense	Oesophagus
COSM5604088	c.6701A>T	p.K2234I	Substitution - Missense	Skin
COSM269578	c.8282C>T	p.T2761M	Substitution - Missense	Large_intestine
COSM1301116	c.6782C>G	p.S2261*	Substitution - Nonsense	Urinary_tract
COSM3501101	c.3472C>T	p.P1158S	Substitution - Missense	Skin
COSM1562940	c.6500A>T	p.K2167I	Substitution - Missense	Large_intestine
COSM1493380	c.1577C>T	p.S526L	Substitution - Missense	Kidney
COSM6008036	c.3344G>A	p.G1115E	Substitution - Missense	Prostate
COSM187703	c.7450C>T	p.R2484W	Substitution - Missense	Prostate
COSM2270837	c.4350G>A	p.L1450L	Substitution - coding silent	Upper_aerodigestive_tract
COSM5594881	c.5141G>A	p.G1714E	Substitution - Missense	Skin
COSM961526	c.6556G>T	p.E2186*	Substitution - Nonsense	Endometrium
COSM361796	c.6850A>T	p.R2284*	Substitution - Nonsense	Lung
COSM1188970	c.2437G>T	p.E813*	Substitution - Nonsense	Lung
COSM3981493	c.447A>T	p.E149D	Substitution - Missense	Ovary
COSM961509	c.3463C>T	p.R1155*	Substitution - Nonsense	Skin
COSM961516	c.4138C>T	p.R1380*	Substitution - Nonsense	Endometrium
COSM1372822	c.3738delA	p.E1249fs*42	Deletion - Frameshift	Large_intestine
COSM3794151	c.8830G>A	p.D2944N	Substitution - Missense	Urinary_tract
COSM3501104	c.5001T>A	p.I1667I	Substitution - coding silent	Skin
COSM5792435	c.3268G>T	p.V1090F	Substitution - Missense	Breast
COSM4647815	c.2785T>C	p.Y929H	Substitution - Missense	Large_intestine
COSM5581653	c.8958C>T	p.S2986S	Substitution - coding silent	Skin
COSM1161120	c.2075C>G	p.S692*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM4544443	c.3574G>A	p.E1192K	Substitution - Missense	Skin
COSM3794150	c.7845G>A	p.R2615R	Substitution - coding silent	Urinary_tract
COSM1215016	c.6366T>G	p.N2122K	Substitution - Missense	Large_intestine
COSM700637	c.4541C>T	p.S1514L	Substitution - Missense	Lung
COSM4054576	c.7995G>T	p.V2665V	Substitution - coding silent	Stomach
COSM961501	c.2568G>A	p.Q856Q	Substitution - coding silent	Endometrium
COSM1629540	c.6396T>C	p.V2132V	Substitution - coding silent	Liver
COSM3501099	c.2455C>T	p.R819C	Substitution - Missense	Skin
COSM961513	c.4042C>T	p.R1348W	Substitution - Missense	Endometrium
COSM961516	c.4138C>T	p.R1380*	Substitution - Nonsense	Stomach
COSM961520	c.4968A>C	p.E1656D	Substitution - Missense	Endometrium
COSM5038634	c.6965_6968delACTT	p.L2323fs*60	Deletion - Frameshift	Liver
COSM5650481	c.7445G>A	p.R2482Q	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5039779	c.7849G>A	p.G2617R	Substitution - Missense	Liver
COSM3667715	c.7093A>G	p.I2365V	Substitution - Missense	Liver
COSM270714	c.5599C>T	p.R1867*	Substitution - Nonsense	Large_intestine
COSM4054559	c.3211T>C	p.C1071R	Substitution - Missense	Stomach
COSM3816032	c.6028C>T	p.Q2010*	Substitution - Nonsense	Breast
COSM245670	c.8831A>G	p.D2944G	Substitution - Missense	Prostate
COSM961492	c.951A>G	p.S317S	Substitution - coding silent	Endometrium
COSM961515	c.4082G>A	p.S1361N	Substitution - Missense	Endometrium
COSM3706560	c.7660A>G	p.K2554E	Substitution - Missense	Liver
COSM961542	c.8726G>A	p.R2909Q	Substitution - Missense	Endometrium
COSM1478105	c.6194C>T	p.T2065I	Substitution - Missense	Breast
COSM2270790	c.2246G>A	p.G749E	Substitution - Missense	Skin
COSM370767	c.2806G>A	p.D936N	Substitution - Missense	Lung
COSM5383270	c.7523C>T	p.S2508F	Substitution - Missense	Skin
COSM5575227	c.8825A>C	p.E2942A	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4554017	c.608G>A	p.R203K	Substitution - Missense	Skin
COSM1734464	c.1852C>T	p.R618*	Substitution - Nonsense	Pancreas
COSM3377557	c.5849C>T	p.T1950I	Substitution - Missense	Pancreas
COSM3667715	c.7093A>G	p.I2365V	Substitution - Missense	Liver
COSM69207	c.5758_5759insA	p.V1920fs*22	Insertion - Frameshift	Ovary
COSM1372832	c.6597G>A	p.Q2199Q	Substitution - coding silent	Large_intestine
COSM4701979	c.6283delA	p.K2095fs*56	Deletion - Frameshift	Large_intestine
COSM261997	c.8096G>A	p.R2699Q	Substitution - Missense	Large_intestine
COSM3401718	c.8151C>T	p.G2717G	Substitution - coding silent	Central_nervous_system
COSM4510960	c.8677C>T	p.L2893L	Substitution - coding silent	Skin
COSM5906961	c.8029C>T	p.L2677F	Substitution - Missense	Skin
COSM4054563	c.4505G>T	p.R1502M	Substitution - Missense	Stomach
COSM4250928	c.4972A>G	p.T1658A	Substitution - Missense	Prostate
COSM4054570	c.5539A>G	p.M1847V	Substitution - Missense	Stomach
COSM5622554	c.2306A>C	p.N769T	Substitution - Missense	Oesophagus
COSM270714	c.5599C>T	p.R1867*	Substitution - Nonsense	Large_intestine
COSM961530	c.7286+1G>A	p.?	Unknown	Endometrium
COSM961521	c.5206A>G	p.T1736A	Substitution - Missense	Endometrium
COSM961522	c.5522T>C	p.V1841A	Substitution - Missense	Endometrium
COSM4890949	c.8884G>T	p.E2962*	Substitution - Nonsense	Upper_aerodigestive_tract
COSM5417675	c.2721_2722delCA	p.F907fs*5	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM1188972	c.8077G>T	p.D2693Y	Substitution - Missense	Lung
COSM4613391	c.4949delC	p.P1651fs*5	Deletion - Frameshift	Large_intestine
COSM961539	c.7651C>A	p.L2551I	Substitution - Missense	Endometrium
COSM4578217	c.5398T>C	p.S1800P	Substitution - Missense	Bone
COSM3987943	c.3147T>A	p.N1049K	Substitution - Missense	Kidney
COSM1658836	c.3980_3981insGTCA	p.P1329fs*10	Insertion - Frameshift	Salivary_gland
COSM4054553	c.130A>G	p.N44D	Substitution - Missense	Stomach
COSM5044237	c.2425G>T	p.G809C	Substitution - Missense	Liver
COSM1215014	c.7333C>T	p.R2445*	Substitution - Nonsense	Skin
COSM1372837	c.7871_7872insA	p.D2627fs*45	Insertion - Frameshift	Large_intestine
COSM2270834	c.4267C>T	p.P1423S	Substitution - Missense	Skin
COSM961534	c.7453C>T	p.R2485C	Substitution - Missense	Kidney
COSM4506446	c.7351C>T	p.P2451S	Substitution - Missense	Skin
COSM4054572	c.6125T>G	p.V2042G	Substitution - Missense	Stomach
COSM4701977	c.5787C>A	p.I1929I	Substitution - coding silent	Large_intestine
COSM4753650	c.7448G>A	p.R2483Q	Substitution - Missense	Stomach
COSM1963647	c.6858G>A	p.L2286L	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM6001794	c.2728C>T	p.R910*	Substitution - Nonsense	Prostate
COSM3794147	c.2873C>G	p.T958S	Substitution - Missense	Urinary_tract
COSM1372838	c.7893A>G	p.E2631E	Substitution - coding silent	Large_intestine
COSM961533	c.7446G>A	p.R2482R	Substitution - coding silent	Endometrium
COSM3936744	c.5141G>T	p.G1714V	Substitution - Missense	Oesophagus
COSM4914770	c.5005G>A	p.D1669N	Substitution - Missense	Liver
COSM3401717	c.7707A>G	p.K2569K	Substitution - coding silent	Central_nervous_system
COSM4250928	c.4972A>G	p.T1658A	Substitution - Missense	Large_intestine
COSM261995	c.3724C>T	p.R1242*	Substitution - Nonsense	Large_intestine
COSM4982201	c.7710G>A	p.Q2570Q	Substitution - coding silent	Oesophagus
COSM4571587	c.5126T>G	p.L1709R	Substitution - Missense	Skin
COSM3706559	c.4564A>T	p.S1522C	Substitution - Missense	Breast
COSM961490	c.264C>A	p.F88L	Substitution - Missense	Endometrium
COSM4841894	c.537C>G	p.L179L	Substitution - coding silent	Cervix
COSM5068875	c.6001C>A	p.Q2001K	Substitution - Missense	Large_intestine
COSM4825280	c.8197C>G	p.L2733V	Substitution - Missense	Cervix
COSM78083	c.1A>G	p.M1V	Substitution - Missense	Ovary
COSM392293	c.2897_2898delAG	p.K966fs*3	Deletion - Frameshift	Lung
COSM4926485	c.7421G>A	p.R2474H	Substitution - Missense	Liver
COSM1562939	c.7045G>C	p.D2349H	Substitution - Missense	Large_intestine
COSM4054566	c.5031T>A	p.Y1677*	Substitution - Nonsense	Stomach
COSM1301115	c.4333C>T	p.H1445Y	Substitution - Missense	Urinary_tract
COSM5920847	c.6782C>T	p.S2261L	Substitution - Missense	Skin
COSM4054578	c.9181C>T	p.P3061S	Substitution - Missense	Stomach
COSM5367861	c.7726_7727insA	p.R2578fs*9	Insertion - Frameshift	Large_intestine
COSM2270835	c.4281G>T	p.E1427D	Substitution - Missense	Upper_aerodigestive_tract
COSM5420113	c.3888C>T	p.D1296D	Substitution - coding silent	Pancreas
COSM961502	c.2596C>T	p.R866*	Substitution - Nonsense	Large_intestine
COSM3794148	c.7223C>T	p.S2408L	Substitution - Missense	Urinary_tract
COSM1193063	c.6229delA	p.R2077fs*74	Deletion - Frameshift	Lung
COSM361797	c.8726G>T	p.R2909L	Substitution - Missense	Lung
COSM1644772	c.3658-2A>T	p.?	Unknown	Salivary_gland
COSM354717	c.6300C>T	p.S2100S	Substitution - coding silent	Lung
COSM5417993	c.1180G>C	p.G394R	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM187703	c.7450C>T	p.R2484W	Substitution - Missense	Endometrium
COSM261995	c.3724C>T	p.R1242*	Substitution - Nonsense	Endometrium
COSM1301117	c.7141G>C	p.D2381H	Substitution - Missense	Urinary_tract
COSM3501114	c.8066C>A	p.P2689Q	Substitution - Missense	Skin
COSM4753634	c.1507G>A	p.A503T	Substitution - Missense	Stomach
COSM961507	c.3157C>T	p.R1053*	Substitution - Nonsense	Endometrium
COSM1286175	c.6862A>G	p.T2288A	Substitution - Missense	Autonomic_ganglia
COSM1741191	c.2553_2554insC	p.V853fs*8	Insertion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM1215014	c.7333C>T	p.R2445*	Substitution - Nonsense	Skin
COSM5021830	c.6054G>A	p.K2018K	Substitution - coding silent	Bone
COSM3377715	c.7454G>A	p.R2485H	Substitution - Missense	Large_intestine
COSM5520999	c.8187A>G	p.P2729P	Substitution - coding silent	Biliary_tract
COSM4054568	c.5487A>T	p.T1829T	Substitution - coding silent	Stomach
COSM5574753	c.6132_6136delGTCAG	p.S2045fs*7	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM4935362	c.4031G>A	p.W1344*	Substitution - Nonsense	Liver
COSM5574752	c.6425delC	p.S2143fs*8	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM4456167	c.3920_3921AG>GA	p.K1307R	Substitution - Missense	Skin
COSM1372823	c.4139G>A	p.R1380Q	Substitution - Missense	Large_intestine
COSM3794149	c.7243C>T	p.H2415Y	Substitution - Missense	Urinary_tract
COSM4185484	c.3175_3176delTC	p.S1059fs*32	Deletion - Frameshift	Kidney
COSM5418984	c.842G>A	p.G281E	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM2270908	c.7447C>T	p.R2483W	Substitution - Missense	Large_intestine
COSM3501096	c.801C>T	p.P267P	Substitution - coding silent	Skin
COSM1372834	c.7293T>C	p.C2431C	Substitution - coding silent	Large_intestine
COSM3501118	c.9133G>A	p.V3045I	Substitution - Missense	Skin
COSM282784	c.4230G>T	p.E1410D	Substitution - Missense	Large_intestine
COSM1741981	c.5003C>G	p.S1668C	Substitution - Missense	Urinary_tract
COSM2270752	c.308G>A	p.R103H	Substitution - Missense	Stomach
COSM5563240	c.3862C>T	p.Q1288*	Substitution - Nonsense	Prostate
COSM1608355	c.9026G>T	p.S3009I	Substitution - Missense	Liver
COSM5716498	c.7511C>T	p.S2504F	Substitution - Missense	Skin
COSM3501098	c.1581A>T	p.E527D	Substitution - Missense	Skin
COSM1372818	c.1836delA	p.R614fs*7	Deletion - Frameshift	Large_intestine
COSM961507	c.3157C>T	p.R1053*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM1516959	c.5717C>T	p.S1906L	Substitution - Missense	Skin
COSM5716498	c.7511C>T	p.S2504F	Substitution - Missense	Skin
COSM3744597	c.3541G>T	p.E1181*	Substitution - Nonsense	Liver
COSM961503	c.2605G>T	p.D869Y	Substitution - Missense	Endometrium
COSM961504	c.2671G>A	p.V891I	Substitution - Missense	Endometrium
COSM961532	c.7445G>T	p.R2482L	Substitution - Missense	Endometrium
COSM96806	c.3725G>C	p.R1242P	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM433834	c.4971T>A	p.N1657K	Substitution - Missense	Breast
COSM5595897	c.7473C>T	p.L2491L	Substitution - coding silent	Skin
COSM1372831	c.6448T>G	p.L2150V	Substitution - Missense	Cervix
COSM4054574	c.6630G>A	p.K2210K	Substitution - coding silent	Stomach
COSM5816882	c.3298C>T	p.Q1100*	Substitution - Nonsense	Liver
COSM433833	c.4621C>T	p.R1541C	Substitution - Missense	Breast
COSM4498236	c.5308C>T	p.P1770S	Substitution - Missense	Skin
COSM4854747	c.8523G>T	p.L2841L	Substitution - coding silent	Cervix
COSM5673521	c.8867A>T	p.D2956V	Substitution - Missense	Soft_tissue
COSM961506	c.3021A>G	p.K1007K	Substitution - coding silent	Endometrium
COSM5599929	c.4643C>T	p.S1548F	Substitution - Missense	Skin
COSM3786511	c.2061T>C	p.S687S	Substitution - coding silent	Pancreas
COSM3667774	c.8989G>T	p.G2997W	Substitution - Missense	Liver
COSM1629541	c.8068G>T	p.E2690*	Substitution - Nonsense	Liver
COSM1516963	c.3127C>T	p.R1043*	Substitution - Nonsense	Stomach
COSM5889275	c.2554C>T	p.P852S	Substitution - Missense	Skin
COSM5363123	c.3519T>C	p.Y1173Y	Substitution - coding silent	Large_intestine
COSM5368829	c.5566C>A	p.Q1856K	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5547301	c.7364_7368delAGCCT	p.K2455fs*5	Deletion - Frameshift	Prostate
COSM4607149	c.7615C>T	p.R2539*	Substitution - Nonsense	Adrenal_gland
COSM5716498	c.7511C>T	p.S2504F	Substitution - Missense	Skin
COSM187703	c.7450C>T	p.R2484W	Substitution - Missense	Prostate
COSM3744598	c.3802A>G	p.T1268A	Substitution - Missense	Liver
COSM5980721	c.8906C>G	p.A2969G	Substitution - Missense	Upper_aerodigestive_tract
COSM4942658	c.7743G>A	p.K2581K	Substitution - coding silent	Liver
COSM5812923	c.2122A>T	p.K708*	Substitution - Nonsense	Liver
COSM4578217	c.5398T>C	p.S1800P	Substitution - Missense	Bone
COSM270714	c.5599C>T	p.R1867*	Substitution - Nonsense	Large_intestine
COSM261995	c.3724C>T	p.R1242*	Substitution - Nonsense	Urinary_tract
COSM3501106	c.5811C>T	p.S1937S	Substitution - coding silent	Skin
COSM1215014	c.7333C>T	p.R2445*	Substitution - Nonsense	Large_intestine
COSM961511	c.3985C>A	p.P1329T	Substitution - Missense	Endometrium
COSM3886949	c.9116C>T	p.A3039V	Substitution - Missense	Skin
COSM4185614	c.7637G>A	p.R2546Q	Substitution - Missense	Kidney
COSM5599929	c.4643C>T	p.S1548F	Substitution - Missense	Skin
COSM5068876	c.6002A>C	p.Q2001P	Substitution - Missense	Large_intestine
COSM4601809	c.7186G>A	p.E2396K	Substitution - Missense	Upper_aerodigestive_tract
COSM4511686	c.876C>T	p.V292V	Substitution - coding silent	Skin
COSM4701975	c.1122C>T	p.N374N	Substitution - coding silent	Large_intestine
COSM2270790	c.2246G>A	p.G749E	Substitution - Missense	Large_intestine
COSM4944442	c.8082A>G	p.L2694L	Substitution - coding silent	Liver
COSM3501105	c.5556C>T	p.H1852H	Substitution - coding silent	Skin
COSM1372831	c.6448T>G	p.L2150V	Substitution - Missense	Large_intestine
COSM2270906	c.7334G>A	p.R2445Q	Substitution - Missense	Large_intestine
COSM4911951	c.9009C>A	p.L3003L	Substitution - coding silent	Liver
COSM5423563	c.3176delC	p.S1060fs*2	Deletion - Frameshift	Prostate
COSM261995	c.3724C>T	p.R1242*	Substitution - Nonsense	Large_intestine
COSM5478867	c.8373C>A	p.F2791L	Substitution - Missense	Large_intestine
COSM1323214	c.5067C>T	p.V1689V	Substitution - coding silent	Ovary
COSM5422230	c.3869T>G	p.L1290*	Substitution - Nonsense	Prostate
COSM261996	c.7459G>T	p.E2487*	Substitution - Nonsense	Large_intestine
COSM5452836	c.4804A>T	p.I1602L	Substitution - Missense	Large_intestine
COSM5783589	c.2950C>A	p.R984S	Substitution - Missense	Breast
COSM4412499	c.4414A>T	p.S1472C	Substitution - Missense	Oesophagus
COSM4553958	c.606G>A	p.P202P	Substitution - coding silent	Skin
COSM5015280	c.301G>A	p.G101R	Substitution - Missense	Kidney
COSM3377715	c.7454G>A	p.R2485H	Substitution - Missense	Pancreas
COSM1372835	c.7545+1G>T	p.?	Unknown	Large_intestine
COSM961529	c.6799G>T	p.E2267*	Substitution - Nonsense	Endometrium
COSM1290379	c.2745T>A	p.Y915*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM5461176	c.845A>G	p.N282S	Substitution - Missense	Large_intestine
COSM700639	c.3208C>A	p.H1070N	Substitution - Missense	Lung
COSM2270775	c.1497T>A	p.S499S	Substitution - coding silent	Central_nervous_system
COSM961509	c.3463C>T	p.R1155*	Substitution - Nonsense	Endometrium
COSM5559096	c.7907T>C	p.L2636S	Substitution - Missense	Prostate
COSM24288	c.6278C>T	p.T2093I	Substitution - Missense	Skin
COSM3706559	c.4564A>T	p.S1522C	Substitution - Missense	Liver
COSM5575226	c.8011G>C	p.D2671H	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5673520	c.8724T>C	p.A2908A	Substitution - coding silent	Soft_tissue
COSM1215014	c.7333C>T	p.R2445*	Substitution - Nonsense	Liver
COSM2270795	c.2686C>T	p.R896*	Substitution - Nonsense	Prostate
COSM5012865	c.2092+1G>T	p.?	Unknown	Kidney
COSM961528	c.6757G>T	p.E2253*	Substitution - Nonsense	Endometrium
COSM2270763	c.871C>T	p.R291W	Substitution - Missense	Biliary_tract
COSM5362852	c.699C>A	p.F233L	Substitution - Missense	Large_intestine
COSM5520225	c.8440G>A	p.G2814R	Substitution - Missense	Biliary_tract
COSM5599929	c.4643C>T	p.S1548F	Substitution - Missense	Skin
COSM4054575	c.7576C>T	p.Q2526*	Substitution - Nonsense	Stomach
COSM3706557	c.4022A>G	p.D1341G	Substitution - Missense	Liver
COSM4054556	c.1548T>C	p.N516N	Substitution - coding silent	Stomach
COSM5500112	c.8675G>T	p.G2892V	Substitution - Missense	Biliary_tract
COSM1372813	c.844_846delAAT	p.N283delN	Deletion - In frame	Large_intestine
COSM1323213	c.9283_9305del23	p.L3095fs*>13	Deletion - Frameshift	Ovary
COSM5893829	c.926C>T	p.P309L	Substitution - Missense	Skin
COSM261996	c.7459G>T	p.E2487*	Substitution - Nonsense	Endometrium
COSM433830	c.1279C>G	p.L427V	Substitution - Missense	Breast
COSM4054565	c.4691G>T	p.G1564V	Substitution - Missense	Stomach
COSM4841529	c.1030G>A	p.E344K	Substitution - Missense	Cervix
COSM5362855	c.2678C>A	p.P893H	Substitution - Missense	Large_intestine
COSM961538	c.7594G>T	p.G2532*	Substitution - Nonsense	Endometrium
COSM4512303	c.9142C>T	p.P3048S	Substitution - Missense	Skin
COSM961514	c.4058G>A	p.S1353N	Substitution - Missense	Endometrium
COSM3816030	c.5721C>G	p.S1907S	Substitution - coding silent	Breast
COSM2270914	c.7816_7832del17	p.D2606fs*3	Deletion - Frameshift	Large_intestine
COSM4927979	c.2649T>C	p.S883S	Substitution - coding silent	Liver
COSM187703	c.7450C>T	p.R2484W	Substitution - Missense	Prostate
COSM3726219	c.2863G>C	p.V955L	Substitution - Missense	Lung
COSM3706557	c.4022A>G	p.D1341G	Substitution - Missense	Liver
COSM4898483	c.1058C>T	p.S353F	Substitution - Missense	Skin
COSM187703	c.7450C>T	p.R2484W	Substitution - Missense	Large_intestine
COSM700636	c.6698G>T	p.R2233M	Substitution - Missense	Lung
COSM4701976	c.5630C>T	p.P1877L	Substitution - Missense	Large_intestine
COSM961497	c.1484G>A	p.R495Q	Substitution - Missense	Large_intestine
COSM3706560	c.7660A>G	p.K2554E	Substitution - Missense	Liver
COSM4893307	c.8729G>A	p.R2910Q	Substitution - Missense	Skin
COSM1215017	c.6751A>C	p.I2251L	Substitution - Missense	Large_intestine
COSM5568427	c.1452T>C	p.S484S	Substitution - coding silent	Prostate
COSM5623816	c.3490G>C	p.E1164Q	Substitution - Missense	Oesophagus
COSM1372821	c.3737_3738insA	p.E1249fs*25	Insertion - Frameshift	Large_intestine
COSM700632	c.7980A>G	p.L2660L	Substitution - coding silent	Lung
COSM1290380	c.4227delT	p.E1410fs*31	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM1608353	c.57A>G	p.G19G	Substitution - coding silent	Liver
COSM1372828	c.6206_6207delCT	p.L2070fs*2	Deletion - Frameshift	Large_intestine
COSM372790	c.4062C>G	p.I1354M	Substitution - Missense	Lung
COSM4894527	c.5752C>T	p.Q1918*	Substitution - Nonsense	Skin
COSM3501107	c.5981C>T	p.A1994V	Substitution - Missense	Skin
COSM2270811	c.3457C>T	p.P1153S	Substitution - Missense	Large_intestine
COSM270714	c.5599C>T	p.R1867*	Substitution - Nonsense	Endometrium
COSM3816024	c.350C>G	p.S117*	Substitution - Nonsense	Breast
COSM4562330	c.921G>A	p.L307L	Substitution - coding silent	Skin
COSM6015703	c.8564C>T	p.S2855F	Substitution - Missense	Skin
COSM3816028	c.1812G>A	p.Q604Q	Substitution - coding silent	Breast
COSM4850206	c.514C>T	p.Q172*	Substitution - Nonsense	Cervix
COSM349029	c.2578A>G	p.K860E	Substitution - Missense	Lung
COSM4608549	c.5550C>A	p.F1850L	Substitution - Missense	Adrenal_gland
COSM2270919	c.7947G>A	p.P2649P	Substitution - coding silent	Large_intestine
COSM1215014	c.7333C>T	p.R2445*	Substitution - Nonsense	Liver
COSM5793675	c.3000C>T	p.D1000D	Substitution - coding silent	Breast
COSM4509548	c.8255C>T	p.S2752F	Substitution - Missense	Skin
COSM187703	c.7450C>T	p.R2484W	Substitution - Missense	Large_intestine
COSM2270917	c.7864C>A	p.L2622I	Substitution - Missense	Large_intestine
COSM5986542	c.5129_5130insGACCCCA	p.K1711fs*18	Insertion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM5730889	c.3123G>A	p.R1041R	Substitution - coding silent	Breast
COSM5575227	c.8825A>C	p.E2942A	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM700640	c.2686C>A	p.R896R	Substitution - coding silent	Lung
COSM2270834	c.4267C>T	p.P1423S	Substitution - Missense	Skin
COSM4150931	c.308G>C	p.R103P	Substitution - Missense	Kidney
COSM4552174	c.5662G>A	p.G1888R	Substitution - Missense	Skin
COSM187703	c.7450C>T	p.R2484W	Substitution - Missense	Prostate
COSM71633	c.7451G>A	p.R2484Q	Substitution - Missense	Central_nervous_system
COSM700635	c.7464G>C	p.M2488I	Substitution - Missense	Lung
COSM961500	c.2211G>T	p.V737V	Substitution - coding silent	Endometrium
COSM961535	c.7479G>T	p.E2493D	Substitution - Missense	Endometrium
COSM147885	c.9259C>T	p.R3087W	Substitution - Missense	Stomach
COSM4054560	c.3736C>T	p.R1246*	Substitution - Nonsense	Stomach
COSM24290	c.4172A>T	p.Y1391F	Substitution - Missense	Upper_aerodigestive_tract
COSM1317796	c.7162_7163delTG	p.V2389fs*4	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM1629539	c.2981A>T	p.K994M	Substitution - Missense	Liver
COSM215605	c.5650G>C	p.G1884R	Substitution - Missense	Central_nervous_system
COSM3956616	c.1206G>A	p.V402V	Substitution - coding silent	Lung
COSM1215015	c.4306G>A	p.A1436T	Substitution - Missense	Large_intestine
COSM5599929	c.4643C>T	p.S1548F	Substitution - Missense	Skin
COSM961488	c.83T>C	p.L28S	Substitution - Missense	Endometrium
COSM1167852	c.6418_6419insA	p.A2142fs*3	Insertion - Frameshift	Skin
COSM75409	c.1935C>A	p.S645R	Substitution - Missense	Ovary
COSM4499992	c.5701C>T	p.P1901S	Substitution - Missense	Skin
COSM1168805	c.7194C>T	p.H2398H	Substitution - coding silent	Pancreas
COSM5982086	c.4660_4662delTCC	p.S1556delS	Deletion - In frame	Upper_aerodigestive_tract
COSM5383268	c.5810C>T	p.S1937F	Substitution - Missense	Skin
COSM5565144	c.7444C>T	p.R2482W	Substitution - Missense	Prostate
COSM5730492	c.3382G>C	p.E1128Q	Substitution - Missense	Breast
COSM416941	c.5650+1G>T	p.?	Unknown	Urinary_tract
COSM3501110	c.7035C>T	p.F2345F	Substitution - coding silent	Skin
COSM961509	c.3463C>T	p.R1155*	Substitution - Nonsense	Large_intestine
COSM4450626	c.7497delG	p.G2500fs*24	Deletion - Frameshift	Skin
COSM261995	c.3724C>T	p.R1242*	Substitution - Nonsense	Skin
COSM433835	c.5532A>T	p.P1844P	Substitution - coding silent	Breast
COSM1372817	c.1832C>A	p.P611H	Substitution - Missense	Large_intestine
COSM961496	c.1483C>T	p.R495*	Substitution - Nonsense	Endometrium
COSM3690636	c.2727C>T	p.G909G	Substitution - coding silent	Large_intestine
COSM1493381	c.430C>G	p.P144A	Substitution - Missense	Kidney
COSM961541	c.8384A>C	p.K2795T	Substitution - Missense	Endometrium
COSM961491	c.752A>G	p.Y251C	Substitution - Missense	Endometrium
COSM1372821	c.3737_3738insA	p.E1249fs*25	Insertion - Frameshift	Large_intestine
COSM1162119	c.8799G>A	p.L2933L	Substitution - coding silent	Kidney
COSM3501112	c.7683G>A	p.K2561K	Substitution - coding silent	Skin
COSM5604089	c.4748C>T	p.P1583L	Substitution - Missense	Skin
COSM4753646	c.4000A>C	p.K1334Q	Substitution - Missense	Stomach
COSM4491575	c.3828C>T	p.N1276N	Substitution - coding silent	Skin
COSM4935094	c.1594A>T	p.K532*	Substitution - Nonsense	Liver
COSM5417077	c.3757C>T	p.Q1253*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM4054573	c.6290C>T	p.S2097F	Substitution - Missense	Stomach
COSM3501100	c.3073C>T	p.L1025F	Substitution - Missense	Skin
COSM4419270	c.4714C>G	p.P1572A	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1562941	c.6117G>A	p.T2039T	Substitution - coding silent	Large_intestine
COSM700633	c.7960C>T	p.L2654F	Substitution - Missense	Lung
COSM4753651	c.9344G>T	p.*3115L	Nonstop extension	Stomach
COSM961494	c.1079G>T	p.S360I	Substitution - Missense	Endometrium
COSM4390713	c.7477G>A	p.E2493K	Substitution - Missense	Breast
COSM4054558	c.2846A>C	p.N949T	Substitution - Missense	Stomach
COSM1629542	c.8835T>G	p.S2945S	Substitution - coding silent	Liver
COSM5094976	c.2397T>G	p.F799L	Substitution - Missense	Thymus
COSM4701980	c.9338G>T	p.G3113V	Substitution - Missense	Large_intestine
COSM187703	c.7450C>T	p.R2484W	Substitution - Missense	Prostate
COSM25668	c.878G>A	p.R293H	Substitution - Missense	Kidney
COSM961498	c.1585G>T	p.G529C	Substitution - Missense	Endometrium
COSM1301114	c.4193C>G	p.S1398C	Substitution - Missense	Urinary_tract
COSM433833	c.4621C>T	p.R1541C	Substitution - Missense	Breast
COSM961496	c.1483C>T	p.R495*	Substitution - Nonsense	Endometrium
COSM266929	c.7273T>C	p.S2425P	Substitution - Missense	Large_intestine
COSM5444429	c.326G>A	p.R109H	Substitution - Missense	Oesophagus
COSM116052	c.8651A>C	p.Q2884P	Substitution - Missense	Ovary
COSM4578215	c.2367C>T	p.F789F	Substitution - coding silent	Bone
COSM405075	c.7587_7590delATTG	p.L2530fs*1	Deletion - Frameshift	Lung
COSM5456481	c.2293C>A	p.L765I	Substitution - Missense	Large_intestine
COSM700634	c.7582G>A	p.D2528N	Substitution - Missense	Lung
COSM961540	c.8076C>T	p.D2692D	Substitution - coding silent	Prostate
COSM3706555	c.2606A>G	p.D869G	Substitution - Missense	Liver
COSM1372824	c.4829C>T	p.T1610I	Substitution - Missense	Large_intestine
COSM5499210	c.8047G>A	p.G2683S	Substitution - Missense	Biliary_tract
COSM4701978	c.6219C>A	p.S2073S	Substitution - coding silent	Large_intestine
COSM4823701	c.8358G>C	p.Q2786H	Substitution - Missense	Cervix
COSM3816035	c.9193C>A	p.P3065T	Substitution - Missense	Breast
COSM4841056	c.8447G>T	p.R2816I	Substitution - Missense	Cervix
COSM5068877	c.6004A>T	p.K2002*	Substitution - Nonsense	Large_intestine
COSM1372812	c.748G>T	p.D250Y	Substitution - Missense	Large_intestine
COSM961510	c.3923G>A	p.S1308N	Substitution - Missense	Endometrium
COSM3501116	c.8300T>C	p.V2767A	Substitution - Missense	Skin
COSM5575226	c.8011G>C	p.D2671H	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3706556	c.3832A>G	p.N1278D	Substitution - Missense	Liver
COSM5035985	c.8096G>C	p.R2699P	Substitution - Missense	Oesophagus
COSM5635866	c.3974A>C	p.H1325P	Substitution - Missense	Oesophagus
COSM5383269	c.7518G>A	p.K2506K	Substitution - coding silent	Skin
COSM3706555	c.2606A>G	p.D869G	Substitution - Missense	Liver
COSM961531	c.7420C>T	p.R2474C	Substitution - Missense	Endometrium
COSM4547931	c.434G>A	p.S145N	Substitution - Missense	Skin
COSM416942	c.736C>G	p.Q246E	Substitution - Missense	Urinary_tract
COSM4054578	c.9181C>T	p.P3061S	Substitution - Missense	Skin
COSM433832	c.2789C>G	p.S930C	Substitution - Missense	Breast
COSM1629538	c.1277A>G	p.Q426R	Substitution - Missense	Liver
COSM2270762	c.827G>T	p.S276I	Substitution - Missense	Large_intestine
COSM4504299	c.661C>G	p.P221A	Substitution - Missense	Skin
COSM5435309	c.7622G>A	p.R2541Q	Substitution - Missense	Oesophagus
COSM5039232	c.5801C>A	p.S1934*	Substitution - Nonsense	Liver
COSM71633	c.7451G>A	p.R2484Q	Substitution - Missense	Ovary
COSM5574750	c.3224_3240del17	p.C1076fs*10	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM5780956	c.7871G>C	p.R2624T	Substitution - Missense	Breast
COSM1257665	c.4563C>A	p.L1521L	Substitution - coding silent	Oesophagus
COSM3501117	c.8961C>T	p.L2987L	Substitution - coding silent	Skin
COSM5504100	c.3943G>T	p.E1315*	Substitution - Nonsense	Biliary_tract
COSM3501113	c.7964C>T	p.T2655I	Substitution - Missense	Skin
COSM187703	c.7450C>T	p.R2484W	Substitution - Missense	Prostate
COSM4491264	c.3779C>T	p.P1260L	Substitution - Missense	Skin
COSM4054571	c.6055A>G	p.R2019G	Substitution - Missense	Stomach
COSM3936745	c.5428C>T	p.R1810*	Substitution - Nonsense	Oesophagus
COSM3370164	c.9209T>G	p.V3070G	Substitution - Missense	Thyroid
COSM5623817	c.3574G>T	p.E1192*	Substitution - Nonsense	Oesophagus
COSM961493	c.1054A>T	p.I352F	Substitution - Missense	Endometrium
COSM1188973	c.8683G>A	p.E2895K	Substitution - Missense	Lung
COSM3420290	c.5783T>C	p.V1928A	Substitution - Missense	Large_intestine
COSM71633	c.7451G>A	p.R2484Q	Substitution - Missense	Ovary
COSM1257664	c.587C>T	p.S196F	Substitution - Missense	Oesophagus
COSM1193063	c.6229delA	p.R2077fs*74	Deletion - Frameshift	Lung
COSM4837198	c.1529C>T	p.T510I	Substitution - Missense	Cervix
COSM3816024	c.350C>G	p.S117*	Substitution - Nonsense	Soft_tissue
COSM961508	c.3313C>T	p.H1105Y	Substitution - Missense	Endometrium
COSM2270923	c.8294C>T	p.T2765M	Substitution - Missense	Small_intestine
COSM700641	c.56G>C	p.G19A	Substitution - Missense	Lung
COSM1608355	c.9026G>T	p.S3009I	Substitution - Missense	Liver
COSM3501102	c.4352C>T	p.P1451L	Substitution - Missense	Skin
COSM5574751	c.6449_6452delTAAG	p.S2151fs*10	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM4970923	c.3611_3614delCTGG	p.T1204fs*15	Deletion - Frameshift	Central_nervous_system
COSM961524	c.6177A>C	p.Q2059H	Substitution - Missense	Endometrium
COSM1168804	c.597T>C	p.R199R	Substitution - coding silent	Pancreas
COSM2270795	c.2686C>T	p.R896*	Substitution - Nonsense	Prostate
COSM961519	c.4878C>T	p.V1626V	Substitution - coding silent	Upper_aerodigestive_tract
COSM5754684	c.7133A>G	p.E2378G	Substitution - Missense	Large_intestine
COSM3782871	c.5024C>T	p.T1675I	Substitution - Missense	Prostate
COSM4054562	c.4441G>A	p.G1481S	Substitution - Missense	Stomach
COSM5363055	c.9281C>T	p.T3094I	Substitution - Missense	Large_intestine
COSM1168007	c.2282C>T	p.P761L	Substitution - Missense	Skin
COSM4511038	c.8712C>T	p.F2904F	Substitution - coding silent	Skin
COSM5504101	c.5879G>A	p.S1960N	Substitution - Missense	Biliary_tract
COSM961519	c.4878C>T	p.V1626V	Substitution - coding silent	Endometrium
COSM4414821	c.3254G>C	p.R1085T	Substitution - Missense	Kidney
COSM5383267	c.2281C>T	p.P761S	Substitution - Missense	Skin
COSM187703	c.7450C>T	p.R2484W	Substitution - Missense	Large_intestine
COSM4494644	c.4372C>T	p.P1458S	Substitution - Missense	Skin
COSM2270913	c.7772C>T	p.P2591L	Substitution - Missense	Skin
COSM3706558	c.4435-3C>T	p.?	Unknown	Liver
COSM3816025	c.383C>A	p.S128Y	Substitution - Missense	Breast
COSM30242	c.2355_2356delAA	p.K785fs*3	Deletion - Frameshift	Kidney
COSM261994	c.2105G>T	p.R702I	Substitution - Missense	Large_intestine
COSM433839	c.8414A>G	p.Y2805C	Substitution - Missense	Breast
COSM5015280	c.301G>A	p.G101R	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3361607	c.1353A>G	p.S451S	Substitution - coding silent	Kidney
COSM4531498	c.1795G>A	p.V599I	Substitution - Missense	Skin
COSM1286176	c.9202G>T	p.A3068S	Substitution - Missense	Autonomic_ganglia
COSM433836	c.7354C>G	p.L2452V	Substitution - Missense	Breast
COSM4054577	c.8280G>A	p.V2760V	Substitution - coding silent	Stomach
COSM287385	c.7423C>G	p.R2475G	Substitution - Missense	Large_intestine
COSM5558155	c.1572G>T	p.K524N	Substitution - Missense	Prostate
COSM4054564	c.4635T>G	p.P1545P	Substitution - coding silent	Stomach
COSM1372826	c.5890delA	p.T1965fs*7	Deletion - Frameshift	Large_intestine
COSM1215018	c.7016G>T	p.G2339V	Substitution - Missense	Large_intestine
COSM3936743	c.3128G>A	p.R1043Q	Substitution - Missense	Oesophagus
COSM433831	c.2526delG	p.G843fs*30	Deletion - Frameshift	Breast
COSM1257663	c.6402A>C	p.E2134D	Substitution - Missense	Oesophagus
COSM5013946	c.5977T>C	p.F1993L	Substitution - Missense	Kidney
COSM4054561	c.4297C>T	p.Q1433*	Substitution - Nonsense	Stomach
COSM5749548	c.9046C>A	p.L3016I	Substitution - Missense	Genital_tract
COSM4847915	c.1715C>T	p.S572L	Substitution - Missense	Cervix
COSM1372825	c.5690C>T	p.P1897L	Substitution - Missense	Large_intestine
COSM71633	c.7451G>A	p.R2484Q	Substitution - Missense	Large_intestine
COSM4054557	c.2652T>G	p.Y884*	Substitution - Nonsense	Stomach
COSM961489	c.145G>A	p.A49T	Substitution - Missense	Endometrium
COSM1135651	c.6617A>G	p.E2206G	Substitution - Missense	Kidney
COSM961534	c.7453C>T	p.R2485C	Substitution - Missense	Endometrium
COSM961497	c.1484G>A	p.R495Q	Substitution - Missense	Endometrium
COSM4928749	c.8994G>A	p.K2998K	Substitution - coding silent	Liver
COSM5068055	c.5385T>A	p.A1795A	Substitution - coding silent	Large_intestine
COSM1372833	c.6824_6825insA	p.S2277fs*5	Insertion - Frameshift	Large_intestine
COSM4390899	c.1663G>A	p.D555N	Substitution - Missense	Breast
COSM961499	c.2053G>T	p.E685*	Substitution - Nonsense	Endometrium
COSM961527	c.6741C>T	p.D2247D	Substitution - coding silent	Endometrium
COSM4148750	c.7011G>T	p.K2337N	Substitution - Missense	Thyroid
COSM1165812	c.2877G>A	p.L959L	Substitution - coding silent	Large_intestine
COSM961525	c.6322G>T	p.D2108Y	Substitution - Missense	Endometrium
COSM3501103	c.4988C>T	p.P1663L	Substitution - Missense	Skin
COSM4578216	c.4980T>G	p.A1660A	Substitution - coding silent	Bone
COSM5916435	c.860C>T	p.S287F	Substitution - Missense	Skin
COSM261997	c.8096G>A	p.R2699Q	Substitution - Missense	Large_intestine
COSM2270925	c.8388T>G	p.I2796M	Substitution - Missense	Large_intestine
COSM1317796	c.7162_7163delTG	p.V2389fs*4	Deletion - Frameshift	Large_intestine
COSM3786511	c.2061T>C	p.S687S	Substitution - coding silent	Pancreas
COSM961540	c.8076C>T	p.D2692D	Substitution - coding silent	Endometrium
COSM961537	c.7583A>G	p.D2528G	Substitution - Missense	Endometrium
COSM261995	c.3724C>T	p.R1242*	Substitution - Nonsense	Breast
COSM5554959	c.6962G>A	p.G2321D	Substitution - Missense	Prostate
COSM5810314	c.6540A>T	p.P2180P	Substitution - coding silent	Liver
COSM5924641	c.2245G>A	p.G749R	Substitution - Missense	Skin
COSM1963647	c.6858G>A	p.L2286L	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM5042894	c.7913C>T	p.T2638I	Substitution - Missense	Liver
COSM5907658	c.8128G>A	p.G2710R	Substitution - Missense	Skin
COSM961518	c.4725G>A	p.R1575R	Substitution - coding silent	Endometrium
COSM3501108	c.6122A>C	p.K2041T	Substitution - Missense	Skin
COSM5980720	c.8326T>G	p.Y2776D	Substitution - Missense	Upper_aerodigestive_tract
COSM5896254	c.2093-1G>A	p.?	Unknown	Skin
COSM3706556	c.3832A>G	p.N1278D	Substitution - Missense	Liver
COSM3816029	c.5233A>C	p.T1745P	Substitution - Missense	Breast
COSM5430673	c.3344_3345delGA	p.E1116fs*31	Deletion - Frameshift	Oesophagus
COSM3816027	c.467T>G	p.V156G	Substitution - Missense	Breast
COSM5599929	c.4643C>T	p.S1548F	Substitution - Missense	Skin
COSM5383265	c.141C>T	p.A47A	Substitution - coding silent	Skin
COSM961536	c.7548C>A	p.A2516A	Substitution - coding silent	Endometrium
COSM961495	c.1272G>A	p.E424E	Substitution - coding silent	Endometrium
COSM1644773	c.3046C>T	p.R1016*	Substitution - Nonsense	Salivary_gland

> Text Mining based Variations

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PMID	Variation	Cancer	Evidence
26684240	Mutation	Pancreatic Gastrin-Producing Neuroendocrine Tumor	Among 12 GEP-NETs, eight showed mutations of more than one cancer-related gene, including TP53, CNBD1, RB1, APC, BCOR, BRAF, CTNNB1, EGFR, EP300, ERBB3, KDM6A, KRAS, MGA, MLL3, PTEN, RASA1, SMARCB1, SPEN, TBC1D12, and VHL.

Summary
Symbol	MGA
Name	MGA, MAX dimerization protein
Aliases	KIAA0518; MAD5; MXD5; FLJ12634; MAX gene associated; MAX dimerization protein 5; MAX gene-associated protein
Location	15q15
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

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Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant
Q8IWI9	607	S	Phosphoserine	-	No	None detected
Q8IWI9	645	S	Phosphoserine	-	No	None detected
Q8IWI9	851	S	Phosphoserine	-	No	None detected
Q8IWI9	924	S	Phosphoserine	-	No	None detected
Q8IWI9	1208	S	Phosphoserine	-	No	None detected
Q8IWI9	1430	S	Phosphoserine	-	No	None detected
Q8IWI9	1457	S	Phosphoserine	-	No	None detected
Q8IWI9	2226	R	Omega-N-methylarginine	-	No	None detected
Q8IWI9	2502	S	Phosphoserine	-	No	None detected
Q8IWI9	2871	S	Phosphoserine	-	No	None detected
Q8IWI9	2882	S	Phosphoserine	-	No	None detected
Q8IWI9	2939	S	Phosphoserine	-	No	None detected

Summary
Symbol	MGA
Name	MGA, MAX dimerization protein
Aliases	KIAA0518; MAD5; MXD5; FLJ12634; MAX gene associated; MAX dimerization protein 5; MAX gene-associated protein
Location	15q15
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

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Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	5.445	5.229	-0.158	0.379	NS
BRCA	Breast invasive carcinoma	112	1100	6.137	5.751	-0.357	1.77e-07	NS
CESC	Cervical and endocervical cancers	3	306	5.475	5.948	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	5.016	5.024	-0.026	0.852	NS
ESCA	Esophageal carcinoma	11	185	6.08	6.018	-0.032	0.894	NS
GBM	Glioblastoma multiforme	5	166	5.187	4.919	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	5.148	5.135	0.057	0.657	NS
KIRC	Kidney renal clear cell carcinoma	72	534	5.726	5.259	-0.417	1.64e-10	NS
KIRP	Kidney renal papillary cell carcinoma	32	291	5.38	4.877	-0.476	0.000407	NS
LAML	Acute Myeloid Leukemia	0	173	NA	7.845	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	5.296	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	3.933	3.852	-0.038	0.731	NS
LUAD	Lung adenocarcinoma	59	517	5.34	5.382	0.132	0.111	NS
LUSC	Lung squamous cell carcinoma	51	501	5.28	5.452	0.189	0.0159	NS
OV	Ovarian serous cystadenocarcinoma	0	307	NA	5.69	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	5.211	5.109	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	5.273	4.845	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	5.694	5.562	-0.08	0.361	NS
READ	Rectum adenocarcinoma	10	167	5.009	5.192	0.06	0.831	NS
SARC	Sarcoma	2	263	4.582	5.21	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	5.111	5.366	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	5.348	5.724	0.31	0.0166	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	6.237	NA	NA	NA
THCA	Thyroid carcinoma	59	509	5.852	5.327	-0.46	9.32e-12	NS
THYM	Thymoma	2	120	5.784	5.593	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	5.579	5.255	-0.364	0.000139	NS

> Cancer Cell Line Encyclopedia (CCLE)

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Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	8.4
Autonomic ganglia	CHP212	8.2
Autonomic ganglia	IMR32	8.5
Autonomic ganglia	KELLY	9.2
Autonomic ganglia	KPNRTBM1	8.8
Autonomic ganglia	KPNSI9S	7.8
Autonomic ganglia	KPNYN	8.8
Autonomic ganglia	MHHNB11	8.5
Autonomic ganglia	NB1	8.4
Autonomic ganglia	NH6	8.7
Autonomic ganglia	SHSY5Y	9.1
Autonomic ganglia	SIMA	9.1
Autonomic ganglia	SKNAS	8.6
Autonomic ganglia	SKNBE2	9.2
Autonomic ganglia	SKNDZ	8.9
Autonomic ganglia	SKNFI	8.9
Autonomic ganglia	SKNSH	8.3
Biliary tract	HUCCT1	6.9
Biliary tract	HUH28	7.7
Biliary tract	SNU1079	4.7
Biliary tract	SNU1196	8.6
Biliary tract	SNU245	8.2
Biliary tract	SNU308	8.7
Biliary tract	SNU478	8.2
Bone	143B	8.6
Bone	A673	8.4
Bone	CADOES1	8.3
Bone	CAL78	7.6
Bone	G292CLONEA141B1	7.9
Bone	HOS	8.6
Bone	HS706T	7.7
Bone	HS737T	7.6
Bone	HS819T	7.5
Bone	HS821T	7.3
Bone	HS822T	7.1
Bone	HS863T	7.7
Bone	HS870T	7.1
Bone	HS888T	8.2
Bone	MG63	7.6
Bone	MHHES1	8.9
Bone	OUMS27	7.5
Bone	RDES	9.1
Bone	SJSA1	7.3
Bone	SKES1	8.5
Bone	SKNMC	8.6
Bone	SW1353	7.2
Bone	T173	7.7
Bone	TC71	8.9
Bone	U2OS	8.8
Breast	AU565	8.3
Breast	BT20	9
Breast	BT474	8.5
Breast	BT483	8.4
Breast	BT549	7.6
Breast	CAL120	8.5
Breast	CAL148	8.1
Breast	CAL51	8.8
Breast	CAL851	7
Breast	CAMA1	7.3
Breast	DU4475	4.3
Breast	EFM192A	7.9
Breast	EFM19	8.3
Breast	EVSAT	8
Breast	HCC1143	8.7
Breast	HCC1187	8.4
Breast	HCC1395	8.1
Breast	HCC1419	8
Breast	HCC1428	8.6
Breast	HCC1500	7.2
Breast	HCC1569	7.5
Breast	HCC1599	8.2
Breast	HCC1806	8.1
Breast	HCC1937	8
Breast	HCC1954	7.5
Breast	HCC202	7.5
Breast	HCC2157	8.3
Breast	HCC2218	7.8
Breast	HCC38	8.8
Breast	HCC70	7.9
Breast	HDQP1	7.3
Breast	HMC18	7.9
Breast	HS274T	7.8
Breast	HS281T	7.7
Breast	HS343T	7.9
Breast	HS578T	7.2
Breast	HS606T	7.5
Breast	HS739T	7.5
Breast	HS742T	6.8
Breast	JIMT1	7.5
Breast	KPL1	8.3
Breast	MCF7	8.2
Breast	MDAMB134VI	6.3
Breast	MDAMB157	7.4
Breast	MDAMB175VII	6.8
Breast	MDAMB231	7.7
Breast	MDAMB361	8.1
Breast	MDAMB415	7.3
Breast	MDAMB436	8.7
Breast	MDAMB453	7.2
Breast	MDAMB468	8.3
Breast	SKBR3	8.3
Breast	T47D	7.5
Breast	UACC812	8.2
Breast	UACC893	7.4
Breast	YMB1	7.2
Breast	ZR751	6.9
Breast	ZR7530	9.1
Central nervous system	1321N1	7.8
Central nervous system	42MGBA	8.1
Central nervous system	8MGBA	8.3
Central nervous system	A172	7.1
Central nervous system	AM38	7
Central nervous system	BECKER	7.8
Central nervous system	CAS1	7.8
Central nervous system	CCFSTTG1	7.6
Central nervous system	D283MED	7.8
Central nervous system	D341MED	8.2
Central nervous system	DAOY	8.4
Central nervous system	DBTRG05MG	7.7
Central nervous system	DKMG	7.8
Central nervous system	GAMG	8.1
Central nervous system	GB1	7.9
Central nervous system	GI1	7.9
Central nervous system	GMS10	8.1
Central nervous system	GOS3	7
Central nervous system	H4	7.6
Central nervous system	HS683	7.6
Central nervous system	KALS1	7.7
Central nervous system	KG1C	6.9
Central nervous system	KNS42	7.9
Central nervous system	KNS60	8.3
Central nervous system	KNS81	7.8
Central nervous system	KS1	7.7
Central nervous system	LN18	8.8
Central nervous system	LN229	7.5
Central nervous system	M059K	8.1
Central nervous system	MOGGCCM	7.8
Central nervous system	MOGGUVW	7.8
Central nervous system	NMCG1	7.8
Central nervous system	ONS76	7.9
Central nervous system	SF126	7.9
Central nervous system	SF295	6.8
Central nervous system	SNB19	7.9
Central nervous system	SNU1105	7.7
Central nervous system	SNU201	7.6
Central nervous system	SNU466	6.9
Central nervous system	SNU489	7.7
Central nervous system	SNU626	7.4
Central nervous system	SNU738	8
Central nervous system	SW1088	7.3
Central nervous system	SW1783	7.3
Central nervous system	T98G	6.3
Central nervous system	TM31	7.9
Central nervous system	U118MG	7.7
Central nervous system	U138MG	7.8
Central nervous system	U251MG	7.1
Central nervous system	U87MG	7.7
Central nervous system	YH13	8.1
Central nervous system	YKG1	7.9
Endometrium	AN3CA	7.8
Endometrium	COLO684	7.8
Endometrium	EFE184	7.8
Endometrium	EN	8.9
Endometrium	ESS1	7.9
Endometrium	HEC108	8.5
Endometrium	HEC151	8
Endometrium	HEC1A	7.6
Endometrium	HEC1B	8.2
Endometrium	HEC251	9.3
Endometrium	HEC265	7.7
Endometrium	HEC50B	8.8
Endometrium	HEC59	8.4
Endometrium	HEC6	8.4
Endometrium	ISHIKAWAHERAKLIO02ER	8.7
Endometrium	JHUEM1	8.6
Endometrium	JHUEM2	8.3
Endometrium	JHUEM3	8.3
Endometrium	KLE	7.5
Endometrium	MFE280	8.2
Endometrium	MFE296	8
Endometrium	MFE319	8
Endometrium	RL952	7.2
Endometrium	SNGM	8.6
Endometrium	SNU1077	8.2
Endometrium	SNU685	8.3
Endometrium	TEN	7.8
Haematopoietic and lymphoid	697	8
Haematopoietic and lymphoid	A3KAW	8.7
Haematopoietic and lymphoid	A4FUK	8.7
Haematopoietic and lymphoid	ALLSIL	8.8
Haematopoietic and lymphoid	AML193	8
Haematopoietic and lymphoid	AMO1	8.8
Haematopoietic and lymphoid	BCP1	9
Haematopoietic and lymphoid	BDCM	8.1
Haematopoietic and lymphoid	BL41	9.1
Haematopoietic and lymphoid	BL70	9.2
Haematopoietic and lymphoid	BV173	7.4
Haematopoietic and lymphoid	CA46	9.8
Haematopoietic and lymphoid	CI1	8.5
Haematopoietic and lymphoid	CMK115	9.4
Haematopoietic and lymphoid	CMK86	9
Haematopoietic and lymphoid	CMK	9.1
Haematopoietic and lymphoid	CMLT1	8.9
Haematopoietic and lymphoid	COLO775	8.3
Haematopoietic and lymphoid	DAUDI	8.3
Haematopoietic and lymphoid	DB	9.1
Haematopoietic and lymphoid	DEL	7.5
Haematopoietic and lymphoid	DND41	7.3
Haematopoietic and lymphoid	DOHH2	8.6
Haematopoietic and lymphoid	EB1	8.6
Haematopoietic and lymphoid	EB2	8.8
Haematopoietic and lymphoid	EHEB	7.7
Haematopoietic and lymphoid	EJM	9
Haematopoietic and lymphoid	EM2	9.5
Haematopoietic and lymphoid	EOL1	9
Haematopoietic and lymphoid	F36P	8.9
Haematopoietic and lymphoid	GA10	9
Haematopoietic and lymphoid	GDM1	8.5
Haematopoietic and lymphoid	GRANTA519	8.5
Haematopoietic and lymphoid	HDLM2	7.2
Haematopoietic and lymphoid	HDMYZ	8.2
Haematopoietic and lymphoid	HEL9217	9.4
Haematopoietic and lymphoid	HEL	9.4
Haematopoietic and lymphoid	HH	8.4
Haematopoietic and lymphoid	HL60	10
Haematopoietic and lymphoid	HPBALL	8.4
Haematopoietic and lymphoid	HS604T	7.8
Haematopoietic and lymphoid	HS611T	8.5
Haematopoietic and lymphoid	HS616T	7.7
Haematopoietic and lymphoid	HS751T	7.7
Haematopoietic and lymphoid	HT	9
Haematopoietic and lymphoid	HTK	8.4
Haematopoietic and lymphoid	HUNS1	8.5
Haematopoietic and lymphoid	HUT102	7.1
Haematopoietic and lymphoid	HUT78	8.5
Haematopoietic and lymphoid	JEKO1	7.9
Haematopoietic and lymphoid	JK1	8
Haematopoietic and lymphoid	JM1	9.3
Haematopoietic and lymphoid	JURKAT	8.9
Haematopoietic and lymphoid	JURLMK1	8.3
Haematopoietic and lymphoid	JVM2	8.4
Haematopoietic and lymphoid	JVM3	8.5
Haematopoietic and lymphoid	K562	8.2
Haematopoietic and lymphoid	KARPAS299	5.9
Haematopoietic and lymphoid	KARPAS422	9
Haematopoietic and lymphoid	KARPAS620	9.4
Haematopoietic and lymphoid	KASUMI1	9.2
Haematopoietic and lymphoid	KASUMI2	8.5
Haematopoietic and lymphoid	KASUMI6	8.8
Haematopoietic and lymphoid	KCL22	8.2
Haematopoietic and lymphoid	KE37	8.3
Haematopoietic and lymphoid	KE97	7.6
Haematopoietic and lymphoid	KG1	8.5
Haematopoietic and lymphoid	KHM1B	8.1
Haematopoietic and lymphoid	KIJK	4.5
Haematopoietic and lymphoid	KMH2	8.9
Haematopoietic and lymphoid	KMM1	8.2
Haematopoietic and lymphoid	KMS11	8.2
Haematopoietic and lymphoid	KMS12BM	9.7
Haematopoietic and lymphoid	KMS18	7.7
Haematopoietic and lymphoid	KMS20	8.9
Haematopoietic and lymphoid	KMS21BM	8.7
Haematopoietic and lymphoid	KMS26	7.8
Haematopoietic and lymphoid	KMS27	7.6
Haematopoietic and lymphoid	KMS28BM	8.2
Haematopoietic and lymphoid	KMS34	8.1
Haematopoietic and lymphoid	KO52	8.8
Haematopoietic and lymphoid	KOPN8	8.3
Haematopoietic and lymphoid	KU812	9.4
Haematopoietic and lymphoid	KYO1	8.2
Haematopoietic and lymphoid	L1236	8.5
Haematopoietic and lymphoid	L363	9.6
Haematopoietic and lymphoid	L428	8.1
Haematopoietic and lymphoid	L540	6.9
Haematopoietic and lymphoid	LAMA84	8.2
Haematopoietic and lymphoid	LOUCY	9.4
Haematopoietic and lymphoid	LP1	7.7
Haematopoietic and lymphoid	M07E	9.4
Haematopoietic and lymphoid	MC116	8.8
Haematopoietic and lymphoid	ME1	7.6
Haematopoietic and lymphoid	MEC1	8.8
Haematopoietic and lymphoid	MEC2	9
Haematopoietic and lymphoid	MEG01	8.7
Haematopoietic and lymphoid	MHHCALL2	9.2
Haematopoietic and lymphoid	MHHCALL3	8.2
Haematopoietic and lymphoid	MHHCALL4	8.2
Haematopoietic and lymphoid	MINO	8.6
Haematopoietic and lymphoid	MJ	8.3
Haematopoietic and lymphoid	MM1S	8.7
Haematopoietic and lymphoid	MOLM13	8.9
Haematopoietic and lymphoid	MOLM16	9.7
Haematopoietic and lymphoid	MOLM6	8.2
Haematopoietic and lymphoid	MOLP2	8.2
Haematopoietic and lymphoid	MOLP8	8.8
Haematopoietic and lymphoid	MOLT13	8.9
Haematopoietic and lymphoid	MOLT16	8.8
Haematopoietic and lymphoid	MOLT4	9.3
Haematopoietic and lymphoid	MONOMAC1	8.8
Haematopoietic and lymphoid	MONOMAC6	9
Haematopoietic and lymphoid	MOTN1	7.5
Haematopoietic and lymphoid	MUTZ5	8.5
Haematopoietic and lymphoid	MV411	8.9
Haematopoietic and lymphoid	NALM19	7.9
Haematopoietic and lymphoid	NALM1	8.2
Haematopoietic and lymphoid	NALM6	8
Haematopoietic and lymphoid	NAMALWA	8.5
Haematopoietic and lymphoid	NB4	9.5
Haematopoietic and lymphoid	NCIH929	8.3
Haematopoietic and lymphoid	NCO2	8.9
Haematopoietic and lymphoid	NOMO1	9
Haematopoietic and lymphoid	NUDHL1	7.8
Haematopoietic and lymphoid	NUDUL1	9.2
Haematopoietic and lymphoid	OCIAML2	8.7
Haematopoietic and lymphoid	OCIAML3	8
Haematopoietic and lymphoid	OCIAML5	7.9
Haematopoietic and lymphoid	OCILY10	9.3
Haematopoietic and lymphoid	OCILY19	7.6
Haematopoietic and lymphoid	OCILY3	8.5
Haematopoietic and lymphoid	OCIM1	8.7
Haematopoietic and lymphoid	OPM2	9
Haematopoietic and lymphoid	P12ICHIKAWA	9.7
Haematopoietic and lymphoid	P31FUJ	8.8
Haematopoietic and lymphoid	P3HR1	9.1
Haematopoietic and lymphoid	PCM6	8.4
Haematopoietic and lymphoid	PEER	9
Haematopoietic and lymphoid	PF382	8.6
Haematopoietic and lymphoid	PFEIFFER	9
Haematopoietic and lymphoid	PL21	8.2
Haematopoietic and lymphoid	RAJI	8.6
Haematopoietic and lymphoid	RCHACV	9.1
Haematopoietic and lymphoid	REC1	9.2
Haematopoietic and lymphoid	REH	9.1
Haematopoietic and lymphoid	RI1	7.7
Haematopoietic and lymphoid	RL	8.9
Haematopoietic and lymphoid	RPMI8226	8.1
Haematopoietic and lymphoid	RPMI8402	9
Haematopoietic and lymphoid	RS411	8.6
Haematopoietic and lymphoid	SEM	8.7
Haematopoietic and lymphoid	SET2	9
Haematopoietic and lymphoid	SIGM5	8.9
Haematopoietic and lymphoid	SKM1	8.5
Haematopoietic and lymphoid	SKMM2	8.3
Haematopoietic and lymphoid	SR786	8
Haematopoietic and lymphoid	ST486	9.3
Haematopoietic and lymphoid	SUDHL10	7.6
Haematopoietic and lymphoid	SUDHL1	6.3
Haematopoietic and lymphoid	SUDHL4	7.8
Haematopoietic and lymphoid	SUDHL5	9.3
Haematopoietic and lymphoid	SUDHL6	8.7
Haematopoietic and lymphoid	SUDHL8	9.1
Haematopoietic and lymphoid	SUPB15	8.8
Haematopoietic and lymphoid	SUPHD1	6.9
Haematopoietic and lymphoid	SUPM2	7.3
Haematopoietic and lymphoid	SUPT11	9
Haematopoietic and lymphoid	SUPT1	8.4
Haematopoietic and lymphoid	TALL1	9.5
Haematopoietic and lymphoid	TF1	8.3
Haematopoietic and lymphoid	THP1	9.3
Haematopoietic and lymphoid	TO175T	7.3
Haematopoietic and lymphoid	TOLEDO	9.1
Haematopoietic and lymphoid	U266B1	8.6
Haematopoietic and lymphoid	U937	8.3
Haematopoietic and lymphoid	UT7	9.2
Haematopoietic and lymphoid	WSUDLCL2	7.6
Kidney	769P	6.9
Kidney	786O	6.9
Kidney	A498	8.8
Kidney	A704	6
Kidney	ACHN	7.1
Kidney	BFTC909	8.7
Kidney	CAKI1	7.8
Kidney	CAKI2	7.9
Kidney	CAL54	7
Kidney	KMRC1	8
Kidney	KMRC20	8.1
Kidney	KMRC2	6.5
Kidney	KMRC3	8.1
Kidney	OSRC2	8.2
Kidney	RCC10RGB	7
Kidney	SNU1272	4.3
Kidney	SNU349	6.5
Kidney	TUHR10TKB	6.7
Kidney	TUHR14TKB	7.7
Kidney	TUHR4TKB	6.7
Kidney	VMRCRCW	7.4
Kidney	VMRCRCZ	7.5
Large intestine	C2BBE1	7.9
Large intestine	CCK81	7.9
Large intestine	CL11	6
Large intestine	CL14	8
Large intestine	CL34	8.4
Large intestine	CL40	4.2
Large intestine	COLO205	8
Large intestine	COLO320	8.5
Large intestine	COLO678	7.8
Large intestine	CW2	8.5
Large intestine	DLD1	7.5
Large intestine	GP2D	8.3
Large intestine	HCC56	8.1
Large intestine	HCT116	8.2
Large intestine	HCT15	8
Large intestine	HS675T	7.1
Large intestine	HS698T	7
Large intestine	HT115	8.5
Large intestine	HT29	7.3
Large intestine	HT55	8.3
Large intestine	KM12	7.5
Large intestine	LOVO	7.8
Large intestine	LS1034	7.6
Large intestine	LS123	8.1
Large intestine	LS180	8.2
Large intestine	LS411N	7.3
Large intestine	LS513	7.6
Large intestine	MDST8	7
Large intestine	NCIH508	8
Large intestine	NCIH716	8.2
Large intestine	NCIH747	7.8
Large intestine	OUMS23	8.5
Large intestine	RCM1	8.1
Large intestine	RKO	7.9
Large intestine	SKCO1	8.3
Large intestine	SNU1040	8.6
Large intestine	SNU1197	8
Large intestine	SNU175	8.4
Large intestine	SNU283	7.7
Large intestine	SNU407	8.2
Large intestine	SNU503	7.8
Large intestine	SNU61	8.2
Large intestine	SNU81	7.4
Large intestine	SNUC1	7
Large intestine	SNUC2A	8.7
Large intestine	SNUC4	8.1
Large intestine	SNUC5	8.5
Large intestine	SW1116	8
Large intestine	SW1417	7.5
Large intestine	SW1463	8
Large intestine	SW403	7.9
Large intestine	SW480	8.1
Large intestine	SW48	7.8
Large intestine	SW620	8.3
Large intestine	SW837	9.1
Large intestine	SW948	7.7
Large intestine	T84	8.1
Liver	ALEXANDERCELLS	8.3
Liver	C3A	8.3
Liver	HEP3B217	8.8
Liver	HEPG2	8.4
Liver	HLE	8.4
Liver	HLF	8.1
Liver	HUH1	8.7
Liver	HUH6	7.9
Liver	HUH7	8.3
Liver	JHH1	7.7
Liver	JHH2	6.7
Liver	JHH4	8.1
Liver	JHH5	8.7
Liver	JHH6	8.5
Liver	JHH7	8.6
Liver	LI7	7.8
Liver	PLCPRF5	8.3
Liver	SKHEP1	8.1
Liver	SNU182	8.3
Liver	SNU387	7.6
Liver	SNU398	8.2
Liver	SNU423	8.2
Liver	SNU449	7.8
Liver	SNU475	8
Liver	SNU761	8.4
Liver	SNU878	7.4
Liver	SNU886	7.7
Lung	A549	8
Lung	ABC1	7.8
Lung	BEN	9.2
Lung	CAL12T	8
Lung	CALU1	7.4
Lung	CALU3	7.9
Lung	CALU6	8.4
Lung	CHAGOK1	8.3
Lung	COLO668	8.9
Lung	COLO699	7
Lung	CORL105	6.6
Lung	CORL23	9.1
Lung	CORL24	8.5
Lung	CORL279	6.8
Lung	CORL311	9.4
Lung	CORL47	8.1
Lung	CORL51	8.5
Lung	CORL88	9
Lung	CORL95	8.5
Lung	CPCN	9
Lung	DMS114	8.6
Lung	DMS153	7.1
Lung	DMS273	8.4
Lung	DMS454	8.6
Lung	DMS53	8.6
Lung	DMS79	8.2
Lung	DV90	7.9
Lung	EBC1	9.2
Lung	EPLC272H	7.5
Lung	HARA	8.1
Lung	HCC1171	8.3
Lung	HCC1195	8.1
Lung	HCC15	8.6
Lung	HCC2279	7.8
Lung	HCC2935	8.6
Lung	HCC33	9
Lung	HCC366	8.7
Lung	HCC4006	8.6
Lung	HCC44	8.7
Lung	HCC78	7.7
Lung	HCC827	7.9
Lung	HCC95	8.1
Lung	HLC1	8.1
Lung	HLFA	7.5
Lung	HS229T	7.8
Lung	HS618T	7.4
Lung	IALM	8.9
Lung	KNS62	7.9
Lung	LC1F	8.8
Lung	LC1SQSF	8.4
Lung	LCLC103H	8.8
Lung	LCLC97TM1	8.8
Lung	LK2	7.7
Lung	LOUNH91	7.4
Lung	LU65	8.2
Lung	LU99	8.3
Lung	LUDLU1	8.3
Lung	LXF289	7.9
Lung	MORCPR	8
Lung	NCIH1048	8.1
Lung	NCIH1092	8.5
Lung	NCIH1105	8.7
Lung	NCIH1155	8.2
Lung	NCIH1184	8.7
Lung	NCIH1299	8.5
Lung	NCIH1339	8.1
Lung	NCIH1341	9.3
Lung	NCIH1355	7.9
Lung	NCIH1373	8.2
Lung	NCIH1385	6.8
Lung	NCIH1395	7.7
Lung	NCIH1435	9
Lung	NCIH1436	9
Lung	NCIH1437	8.2
Lung	NCIH146	7.9
Lung	NCIH1563	7
Lung	NCIH1568	8
Lung	NCIH1573	8.3
Lung	NCIH1581	9.1
Lung	NCIH1618	8.4
Lung	NCIH1623	8.5
Lung	NCIH1648	8.4
Lung	NCIH1650	8.4
Lung	NCIH1651	7.8
Lung	NCIH1666	8.6
Lung	NCIH1693	8.6
Lung	NCIH1694	8.8
Lung	NCIH1703	7.8
Lung	NCIH1734	8.3
Lung	NCIH1755	8.4
Lung	NCIH1781	8.5
Lung	NCIH1792	8.6
Lung	NCIH1793	8.5
Lung	NCIH1836	8.9
Lung	NCIH1838	8.9
Lung	NCIH1869	8
Lung	NCIH1876	8.8
Lung	NCIH1915	8.2
Lung	NCIH1930	8.2
Lung	NCIH1944	8.2
Lung	NCIH1963	9.3
Lung	NCIH196	8.3
Lung	NCIH1975	9
Lung	NCIH2009	8.8
Lung	NCIH2023	8.2
Lung	NCIH2029	8.3
Lung	NCIH2030	8.8
Lung	NCIH2066	8.2
Lung	NCIH2081	8.5
Lung	NCIH2085	8.4
Lung	NCIH2087	8
Lung	NCIH209	8.7
Lung	NCIH2106	7.5
Lung	NCIH2110	7.7
Lung	NCIH211	8.6
Lung	NCIH2122	8
Lung	NCIH2126	8.1
Lung	NCIH2141	8.6
Lung	NCIH2170	8.5
Lung	NCIH2171	8.9
Lung	NCIH2172	8.6
Lung	NCIH2196	5.6
Lung	NCIH2227	9.4
Lung	NCIH2228	7.9
Lung	NCIH226	7.4
Lung	NCIH2286	8.9
Lung	NCIH2291	7
Lung	NCIH2342	8.4
Lung	NCIH2347	7.4
Lung	NCIH23	8.1
Lung	NCIH2405	8.2
Lung	NCIH2444	7.6
Lung	NCIH292	8.1
Lung	NCIH322	7.9
Lung	NCIH3255	8.1
Lung	NCIH358	9.3
Lung	NCIH441	8.5
Lung	NCIH446	8
Lung	NCIH460	7.9
Lung	NCIH510	9.1
Lung	NCIH520	8.5
Lung	NCIH522	8.7
Lung	NCIH524	9.1
Lung	NCIH526	8.9
Lung	NCIH596	8.3
Lung	NCIH647	8.1
Lung	NCIH650	8.5
Lung	NCIH661	8.6
Lung	NCIH69	8
Lung	NCIH727	8.3
Lung	NCIH810	8.4
Lung	NCIH82	8.7
Lung	NCIH838	8.6
Lung	NCIH841	8.8
Lung	NCIH854	4.2
Lung	NCIH889	9.3
Lung	PC14	8.1
Lung	RERFLCAD1	8.6
Lung	RERFLCAD2	8.2
Lung	RERFLCAI	8.2
Lung	RERFLCKJ	7.8
Lung	RERFLCMS	7.9
Lung	RERFLCSQ1	8.3
Lung	SBC5	9
Lung	SCLC21H	9.3
Lung	SHP77	9.5
Lung	SKLU1	7.7
Lung	SKMES1	8.5
Lung	SQ1	8.2
Lung	SW1271	8.4
Lung	SW1573	7.5
Lung	SW900	8.7
Lung	VMRCLCD	9
Lung	VMRCLCP	8
Oesophagus	COLO680N	8
Oesophagus	ECGI10	8.6
Oesophagus	KYSE140	7.4
Oesophagus	KYSE150	7.7
Oesophagus	KYSE180	8.6
Oesophagus	KYSE270	8.4
Oesophagus	KYSE30	8.1
Oesophagus	KYSE410	7.5
Oesophagus	KYSE450	7.9
Oesophagus	KYSE510	7.3
Oesophagus	KYSE520	7.9
Oesophagus	KYSE70	6.7
Oesophagus	OE19	8
Oesophagus	OE33	8.5
Oesophagus	TE10	9.2
Oesophagus	TE11	8.2
Oesophagus	TE14	8.5
Oesophagus	TE15	7.6
Oesophagus	TE1	8.4
Oesophagus	TE4	8.4
Oesophagus	TE5	6.3
Oesophagus	TE6	8.7
Oesophagus	TE8	8.3
Oesophagus	TE9	8.3
Oesophagus	TT	8.5
Ovary	59M	7.5
Ovary	A2780	8.6
Ovary	CAOV3	8.1
Ovary	CAOV4	8.6
Ovary	COLO704	8.8
Ovary	COV318	8.4
Ovary	COV362	7.8
Ovary	COV434	8.7
Ovary	COV504	8
Ovary	COV644	7.7
Ovary	EFO21	8.9
Ovary	EFO27	7.9
Ovary	ES2	7.4
Ovary	FUOV1	8.5
Ovary	HEYA8	7.6
Ovary	HS571T	7.4
Ovary	IGROV1	8.7
Ovary	JHOC5	8
Ovary	JHOM1	7.1
Ovary	JHOM2B	8.8
Ovary	JHOS2	7.6
Ovary	JHOS4	8.1
Ovary	KURAMOCHI	8.8
Ovary	MCAS	7.2
Ovary	NIHOVCAR3	9
Ovary	OAW28	7.7
Ovary	OAW42	7.8
Ovary	OC314	8.1
Ovary	OC316	8.1
Ovary	ONCODG1	7.6
Ovary	OV56	8
Ovary	OV7	7.8
Ovary	OV90	9.1
Ovary	OVCAR4	8.1
Ovary	OVCAR8	6.6
Ovary	OVISE	8.4
Ovary	OVK18	8.4
Ovary	OVKATE	8.3
Ovary	OVMANA	8
Ovary	OVSAHO	8.2
Ovary	OVTOKO	8.2
Ovary	RMGI	7.8
Ovary	RMUGS	7
Ovary	SKOV3	9.2
Ovary	SNU119	7.7
Ovary	SNU840	8
Ovary	SNU8	8.1
Ovary	TOV112D	8.8
Ovary	TOV21G	7.9
Ovary	TYKNU	8.5
Pancreas	ASPC1	8.3
Pancreas	BXPC3	7.9
Pancreas	CAPAN1	8.8
Pancreas	CAPAN2	8.4
Pancreas	CFPAC1	8.8
Pancreas	DANG	8.4
Pancreas	HPAC	8.1
Pancreas	HPAFII	7.2
Pancreas	HS766T	7.9
Pancreas	HUPT3	8.7
Pancreas	HUPT4	8
Pancreas	KCIMOH1	4.4
Pancreas	KLM1	7.2
Pancreas	KP2	7.7
Pancreas	KP3	7.9
Pancreas	KP4	8.7
Pancreas	L33	8.4
Pancreas	MIAPACA2	8.6
Pancreas	PANC0203	8.4
Pancreas	PANC0213	8.8
Pancreas	PANC0327	7.6
Pancreas	PANC0403	7.6
Pancreas	PANC0504	7.6
Pancreas	PANC0813	7.3
Pancreas	PANC1005	8
Pancreas	PANC1	8.3
Pancreas	PATU8902	6.9
Pancreas	PATU8988S	7.9
Pancreas	PATU8988T	7.9
Pancreas	PK1	8.1
Pancreas	PK45H	7.7
Pancreas	PK59	7.5
Pancreas	PL45	7.6
Pancreas	PSN1	8.7
Pancreas	QGP1	8.5
Pancreas	SNU213	7.9
Pancreas	SNU324	8.6
Pancreas	SNU410	7.9
Pancreas	SU8686	8.4
Pancreas	SUIT2	8.2
Pancreas	SW1990	7.3
Pancreas	T3M4	8.1
Pancreas	TCCPAN2	7.8
Pancreas	YAPC	8.6
Pleura	ACCMESO1	7.8
Pleura	DM3	6.6
Pleura	ISTMES1	6.9
Pleura	ISTMES2	7.5
Pleura	JL1	7.2
Pleura	MPP89	8.3
Pleura	MSTO211H	7.7
Pleura	NCIH2052	7.5
Pleura	NCIH2452	7.9
Pleura	NCIH28	7.7
Prostate	22RV1	8.6
Prostate	DU145	8.3
Prostate	LNCAPCLONEFGC	8.3
Prostate	MDAPCA2B	8.1
Prostate	NCIH660	8.1
Prostate	PC3	8.3
Prostate	VCAP	9
Salivary gland	A253	8.4
Salivary gland	YD15	7.7
Skin	A101D	7.9
Skin	A2058	7.7
Skin	A375	7.6
Skin	C32	8.1
Skin	CHL1	7.5
Skin	CJM	7.6
Skin	COLO679	6.5
Skin	COLO741	8
Skin	COLO783	8.3
Skin	COLO792	7.3
Skin	COLO800	8.1
Skin	COLO818	7.7
Skin	COLO829	8.1
Skin	COLO849	8.4
Skin	G361	8.2
Skin	GRM	8.3
Skin	HMCB	7.7
Skin	HS294T	7.7
Skin	HS600T	7.4
Skin	HS688AT	7.4
Skin	HS695T	8.2
Skin	HS839T	7.5
Skin	HS852T	8.5
Skin	HS895T	6.9
Skin	HS934T	7.9
Skin	HS936T	5.4
Skin	HS939T	6.8
Skin	HS940T	7.5
Skin	HS944T	7.6
Skin	HT144	7.5
Skin	IGR1	7.4
Skin	IGR37	7.9
Skin	IGR39	8.1
Skin	IPC298	7.6
Skin	K029AX	7.7
Skin	LOXIMVI	7.9
Skin	MALME3M	7.7
Skin	MDAMB435S	7.2
Skin	MELHO	8
Skin	MELJUSO	7.3
Skin	MEWO	7.8
Skin	RPMI7951	8.2
Skin	RVH421	6.9
Skin	SH4	7.2
Skin	SKMEL1	8.2
Skin	SKMEL24	6.6
Skin	SKMEL28	7.8
Skin	SKMEL2	8.2
Skin	SKMEL30	7.1
Skin	SKMEL31	6.9
Skin	SKMEL3	8.2
Skin	SKMEL5	7.7
Skin	UACC257	7.8
Skin	UACC62	7.7
Skin	WM115	7.1
Skin	WM1799	8
Skin	WM2664	7.7
Skin	WM793	7.3
Skin	WM88	8
Skin	WM983B	7.6
Small intestine	HUTU80	9
Soft tissue	A204	8.4
Soft tissue	G401	8.3
Soft tissue	G402	7.6
Soft tissue	GCT	8.3
Soft tissue	HS729	8.5
Soft tissue	HT1080	8
Soft tissue	KYM1	8.6
Soft tissue	MESSA	8.5
Soft tissue	RD	8.4
Soft tissue	RH30	7.3
Soft tissue	RH41	8.5
Soft tissue	RKN	7.7
Soft tissue	S117	8.2
Soft tissue	SJRH30	9.2
Soft tissue	SKLMS1	7.6
Soft tissue	SKUT1	8.5
Soft tissue	TE125T	7.2
Soft tissue	TE159T	7.8
Soft tissue	TE441T	7.6
Soft tissue	TE617T	8.7
Stomach	2313287	8.2
Stomach	AGS	7.6
Stomach	AZ521	8.7
Stomach	ECC10	8.9
Stomach	ECC12	8.9
Stomach	FU97	8.1
Stomach	GCIY	8.2
Stomach	GSS	8.6
Stomach	GSU	7.9
Stomach	HGC27	8.6
Stomach	HS746T	7.3
Stomach	HUG1N	8.3
Stomach	IM95	7.3
Stomach	KATOIII	6.3
Stomach	KE39	7.3
Stomach	LMSU	8.1
Stomach	MKN1	8.3
Stomach	MKN45	7.8
Stomach	MKN74	9.5
Stomach	MKN7	7.6
Stomach	NCCSTCK140	8
Stomach	NCIN87	8.7
Stomach	NUGC2	7.5
Stomach	NUGC3	7.5
Stomach	NUGC4	7.7
Stomach	OCUM1	8.4
Stomach	RERFGC1B	8.5
Stomach	SH10TC	7.8
Stomach	SNU16	8.8
Stomach	SNU1	4.1
Stomach	SNU216	8.3
Stomach	SNU520	8.6
Stomach	SNU5	7.5
Stomach	SNU601	7.6
Stomach	SNU620	7.5
Stomach	SNU668	8.3
Stomach	SNU719	4
Stomach	TGBC11TKB	8.1
Thyroid	8305C	7.1
Thyroid	8505C	7.5
Thyroid	BCPAP	8.3
Thyroid	BHT101	8.7
Thyroid	CAL62	9
Thyroid	CGTHW1	7.5
Thyroid	FTC133	8.2
Thyroid	FTC238	7.4
Thyroid	ML1	8.5
Thyroid	SW579	7.8
Thyroid	TT2609C02	8.1
Thyroid	TT	7.4
Upper aerodigestive tract	BHY	8.2
Upper aerodigestive tract	BICR16	7.2
Upper aerodigestive tract	BICR18	8.1
Upper aerodigestive tract	BICR22	7.6
Upper aerodigestive tract	BICR31	8.2
Upper aerodigestive tract	BICR56	8
Upper aerodigestive tract	BICR6	8.2
Upper aerodigestive tract	CAL27	7.5
Upper aerodigestive tract	CAL33	7.4
Upper aerodigestive tract	DETROIT562	7.1
Upper aerodigestive tract	FADU	8.1
Upper aerodigestive tract	HS840T	7.5
Upper aerodigestive tract	HSC2	7.7
Upper aerodigestive tract	HSC3	7.7
Upper aerodigestive tract	HSC4	8.8
Upper aerodigestive tract	PECAPJ15	8.2
Upper aerodigestive tract	PECAPJ34CLONEC12	8.4
Upper aerodigestive tract	PECAPJ41CLONED2	6.8
Upper aerodigestive tract	PECAPJ49	7.8
Upper aerodigestive tract	SCC15	7.4
Upper aerodigestive tract	SCC25	7.4
Upper aerodigestive tract	SCC4	8.6
Upper aerodigestive tract	SCC9	8.2
Upper aerodigestive tract	SNU1076	7.7
Upper aerodigestive tract	SNU1214	7.9
Upper aerodigestive tract	SNU46	8.1
Upper aerodigestive tract	SNU899	7.9
Upper aerodigestive tract	YD10B	8
Upper aerodigestive tract	YD38	7.8
Upper aerodigestive tract	YD8	8.2
Urinary tract	5637	7.4
Urinary tract	639V	8.6
Urinary tract	647V	8.2
Urinary tract	BC3C	8
Urinary tract	BFTC905	9.1
Urinary tract	CAL29	7.4
Urinary tract	HS172T	7.2
Urinary tract	HT1197	7.5
Urinary tract	HT1376	8.2
Urinary tract	J82	7.5
Urinary tract	JMSU1	8.7
Urinary tract	KMBC2	8.3
Urinary tract	KU1919	9.2
Urinary tract	RT11284	8.2
Urinary tract	RT112	7.9
Urinary tract	RT4	7.7
Urinary tract	SCABER	8
Urinary tract	SW1710	7.5
Urinary tract	SW780	8.1
Urinary tract	T24	8
Urinary tract	TCCSUP	7.6
Urinary tract	UMUC1	6.8
Urinary tract	UMUC3	7.5
Urinary tract	VMCUB1	8.2

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	4.4
Adrenal gland	6.9
Appendix	7.4
Bone marrow	5.8
Breast	8.7
Cerebral cortex	5.2
Cervix, uterine	11.3
Colon	4.5
Duodenum	3.8
Endometrium	12.3
Epididymis	7.8
Esophagus	5
Fallopian tube	9.5
Gallbladder	6.6
Heart muscle	2.9
Kidney	5.8
Liver	2.6
Lung	6.4
Lymph node	9.1
Ovary	14.8
Pancreas	1
Parathyroid gland	15
Placenta	9.8
Prostate	9.2
Rectum	5.8
Salivary gland	2.2
Seminal vesicle	7.6
Skeletal muscle	1.7
Skin	7.4
Small intestine	3.5
Smooth muscle	8.6
Spleen	9.5
Stomach	4.2
Testis	16
Thyroid gland	12.6
Tonsil	7.3
Urinary bladder	6.3

> Text Mining based Expression

[ TOP ]

PMID	Expression	Cancer	Evidence
26490322	Overexpression	Breast Carcinoma	MGA mRNA was expressed in the peripheral blood of 39 breast cancer patients and in none of the women from the control group.

Summary
Symbol	MGA
Name	MGA, MAX dimerization protein
Aliases	KIAA0518; MAD5; MXD5; FLJ12634; MAX gene associated; MAX dimerization protein 5; MAX gene-associated protein
Location	15q15
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.275	1.92e-08	39.4	52.7	7.9	Loss
BRCA	Breast invasive carcinoma	1075	0.168	3.25e-08	36.3	57.1	6.6	Loss
CESC	Cervical and endocervical cancers	292	0.538	2.74e-23	24.7	62	13.4	Neutral
COAD	Colon adenocarcinoma	449	0.267	9.47e-09	37.9	58.6	3.6	Loss
ESCA	Esophageal carcinoma	183	0.157	0.0339	37.2	49.2	13.7	Loss
GBM	Glioblastoma multiforme	147	0.337	3.03e-05	29.3	64.6	6.1	Neutral
HNSC	Head and Neck squamous cell carcinoma	514	0.11	0.0127	23.9	62.1	14	Neutral
KIRC	Kidney renal clear cell carcinoma	525	0.188	1.5e-05	7.4	87.8	4.8	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	0.078	0.187	11.8	86.5	1.7	Neutral
LAML	Acute Myeloid Leukemia	166	-0.031	0.688	2.4	97.6	0	Neutral
LGG	Brain Lower Grade Glioma	513	0.235	7.6e-08	12.3	86.2	1.6	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.108	0.0395	19.5	71.2	9.3	Neutral
LUAD	Lung adenocarcinoma	512	0.242	3.13e-08	53.3	40.4	6.2	Loss
LUSC	Lung squamous cell carcinoma	498	0.298	1.09e-11	35.5	44.6	19.9	Loss
OV	Ovarian serous cystadenocarcinoma	300	0.431	5.07e-15	63.7	33.3	3	Loss
PAAD	Pancreatic adenocarcinoma	177	0.298	5.56e-05	19.2	74.6	6.2	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	0.162	0.0398	2.5	89.5	8	Neutral
PRAD	Prostate adenocarcinoma	491	0.22	8.17e-07	12.8	85.5	1.6	Neutral
READ	Rectum adenocarcinoma	164	0.114	0.144	48.2	49.4	2.4	Loss
SARC	Sarcoma	255	0.288	2.85e-06	23.9	54.9	21.2	Neutral
SKCM	Skin Cutaneous Melanoma	367	0.312	9.87e-10	25.1	54.8	20.2	Neutral
STAD	Stomach adenocarcinoma	413	0.042	0.396	27.6	65.4	7	Neutral
TGCT	Testicular Germ Cell Tumors	150	0.483	3.96e-10	22.7	42	35.3	Gain
THCA	Thyroid carcinoma	497	0.056	0.213	1.8	98.2	0	Neutral
THYM	Thymoma	119	0.051	0.58	1.7	89.1	9.2	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.136	0.00165	25.7	72.4	1.9	Neutral

Summary
Symbol	MGA
Name	MGA, MAX dimerization protein
Aliases	KIAA0518; MAD5; MXD5; FLJ12634; MAX gene associated; MAX dimerization protein 5; MAX gene-associated protein
Location	15q15
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

[ TOP ]

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.282	3.81e-09	17	408	-0.004	1.11e-06	NS/NA
BRCA	Breast invasive carcinoma	-0.241	7.83e-13	83	785	0.002	1.6e-39	NS/NA
CESC	Cervical and endocervical cancers	-0.335	1.97e-09	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.318	8.62e-09	19	297	0.007	1.49e-25	NS/NA
ESCA	Esophageal carcinoma	-0.265	0.000201	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.307	0.0131	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.272	1.45e-10	20	522	0.005	6.83e-17	NS/NA
KIRC	Kidney renal clear cell carcinoma	-0.203	0.000161	24	319	0.098	6.35e-06	NS/NA
KIRP	Kidney renal papillary cell carcinoma	-0.348	8.7e-10	23	275	0.014	1.81e-09	NS/NA
LAML	Acute Myeloid Leukemia	-0.291	0.000127	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	-0.461	0	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.249	3.28e-07	41	373	0.185	2.88e-14	NS/NA
LUAD	Lung adenocarcinoma	-0.151	0.000984	21	456	-0.071	0.00311	NS/NA
LUSC	Lung squamous cell carcinoma	-0.153	0.00291	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	-0.367	0.336	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.411	1.08e-08	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.232	0.00145	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.309	3.84e-13	35	498	-0.001	0.00737	NS/NA
READ	Rectum adenocarcinoma	-0.277	0.0052	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.275	6.79e-06	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.328	3.56e-13	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.429	0	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.671	0	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.184	1.18e-05	50	509	0.009	0.0092	NS/NA
THYM	Thymoma	-0.275	0.00225	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.183	7.4e-05	34	431	-0.003	0.000133	NS/NA

Summary
Symbol	MGA
Name	MGA, MAX dimerization protein
Aliases	KIAA0518; MAD5; MXD5; FLJ12634; MAX gene associated; MAX dimerization protein 5; MAX gene-associated protein
Location	15q15
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Level	Level Name
Adrenal gland	1	Low
Appendix	1	Low
Bone marrow	2	Medium
Breast	2	Medium
Bronchus	2	Medium
Caudate	2	Medium
Cerebellum	2	Medium
Cerebral cortex	2	Medium
Cervix, uterine	2	Medium
Colon	2	Medium
Duodenum	1	Low
Endometrium	1	Low
Epididymis	2	Medium
Esophagus	2	Medium
Fallopian tube	2	Medium
Gallbladder	2	Medium
Heart muscle	0	Not detected
Hippocampus	2	Medium
Kidney	1	Low
Liver	0	Not detected
Lung	1	Low
Lymph node	1	Low
Nasopharynx	2	Medium
Oral mucosa	2	Medium
Ovary	0	Not detected
Pancreas	1	Low
Parathyroid gland	1	Low
Placenta	2	Medium
Prostate	0	Not detected
Rectum	1	Low
Salivary gland	2	Medium
Seminal vesicle	0	Not detected
Skeletal muscle	2	Medium
Skin	2	Medium
Small intestine	1	Low
Smooth muscle	2	Medium
Soft tissue	3	High
Spleen	0	Not detected
Stomach	2	Medium
Testis	2	Medium
Thyroid gland	1	Low
Tonsil	2	Medium
Urinary bladder	1	Low
Vagina	1	Low

Summary
Symbol	MGA
Name	MGA, MAX dimerization protein
Aliases	KIAA0518; MAD5; MXD5; FLJ12634; MAX gene associated; MAX dimerization protein 5; MAX gene-associated protein
Location	15q15
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.89	NS	24476821
BRCA	Breast invasive carcinoma	521	0.63	NS	23000897
COAD	Colon adenocarcinoma	149	0.105	NS	22810696
GBM	Glioblastoma multiforme	157	0.000143	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	1.06e-09	Significant	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.0202	Significant	26536169
LGG	Brain Lower Grade Glioma	513	5.15e-38	Significant	26824661
LUAD	Lung adenocarcinoma	230	0.00108	Significant	25079552
LUSC	Lung squamous cell carcinoma	178	0.0279	Significant	22960745
OV	Ovarian serous cystadenocarcinoma	287	0.00199	Significant	21720365
PRAD	Prostate adenocarcinoma	333	7.97e-05	Significant	26544944
READ	Rectum adenocarcinoma	67	0.155	NS	22810696
SKCM	Skin Cutaneous Melanoma	315	0.407	NS	26091043
STAD	Stomach adenocarcinoma	277	1.1e-09	Significant	25079317
THCA	Thyroid carcinoma	391	0.381	NS	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	0.174	NS	23636398

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	1.001	0.997	NS
BRCA	Breast invasive carcinoma	1079	1.256	0.299	NS
CESC	Cervical and endocervical cancers	291	0.904	0.77	NS
COAD	Colon adenocarcinoma	439	1.2	0.517	NS
ESCA	Esophageal carcinoma	184	0.768	0.374	NS
GBM	Glioblastoma multiforme	158	0.761	0.306	NS
HNSC	Head and Neck squamous cell carcinoma	518	0.693	0.0671	NS
KIRC	Kidney renal clear cell carcinoma	531	0.467	0.00101	Longer
KIRP	Kidney renal papillary cell carcinoma	287	1.18	0.686	NS
LAML	Acute Myeloid Leukemia	149	0.672	0.191	NS
LGG	Brain Lower Grade Glioma	511	2.753	0.000288	Shorter
LIHC	Liver hepatocellular carcinoma	365	0.97	0.902	NS
LUAD	Lung adenocarcinoma	502	0.834	0.403	NS
LUSC	Lung squamous cell carcinoma	494	1.07	0.723	NS
OV	Ovarian serous cystadenocarcinoma	303	1.367	0.134	NS
PAAD	Pancreatic adenocarcinoma	177	1.048	0.867	NS
PCPG	Pheochromocytoma and Paraganglioma	179	774289588.141	0.0511	NS
PRAD	Prostate adenocarcinoma	497	0.995	0.997	NS
READ	Rectum adenocarcinoma	159	0.537	0.411	NS
SARC	Sarcoma	259	1.135	0.674	NS
SKCM	Skin Cutaneous Melanoma	459	1.151	0.463	NS
STAD	Stomach adenocarcinoma	388	1.071	0.771	NS
TGCT	Testicular Germ Cell Tumors	134	1.255	0.872	NS
THCA	Thyroid carcinoma	500	0.581	0.474	NS
THYM	Thymoma	119	0.309	0.172	NS
UCEC	Uterine Corpus Endometrial Carcinoma	543	0.846	0.629	NS

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	-0.06	0.229	NS
BRCA	Breast invasive carcinoma	1071	0.001	0.974	NS
CESC	Cervical and endocervical cancers	167	-0.047	0.543	NS
COAD	Colon adenocarcinoma	445	0.014	0.765	NS
ESCA	Esophageal carcinoma	162	0.006	0.937	NS
HNSC	Head and Neck squamous cell carcinoma	448	0.036	0.445	NS
KIRC	Kidney renal clear cell carcinoma	531	-0.128	0.00315	Lower
KIRP	Kidney renal papillary cell carcinoma	260	-0.1	0.107	NS
LIHC	Liver hepatocellular carcinoma	347	0.097	0.0699	NS
LUAD	Lung adenocarcinoma	507	-0.007	0.872	NS
LUSC	Lung squamous cell carcinoma	497	0.017	0.7	NS
OV	Ovarian serous cystadenocarcinoma	302	-0.019	0.748	NS
PAAD	Pancreatic adenocarcinoma	176	-0.003	0.972	NS
READ	Rectum adenocarcinoma	156	0.05	0.536	NS
SKCM	Skin Cutaneous Melanoma	410	-0.05	0.31	NS
STAD	Stomach adenocarcinoma	392	0.068	0.182	NS
TGCT	Testicular Germ Cell Tumors	81	-0.29	0.00864	Lower
THCA	Thyroid carcinoma	499	-0.159	0.000376	Lower
UCEC	Uterine Corpus Endometrial Carcinoma	501	0.048	0.279	NS

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	-0.074	0.225	NS
HNSC	Head and Neck squamous cell carcinoma	498	0.213	1.59e-06	Higher
KIRC	Kidney renal clear cell carcinoma	525	-0.108	0.0131	Lower
LGG	Brain Lower Grade Glioma	514	0.086	0.0508	NS
LIHC	Liver hepatocellular carcinoma	366	0.153	0.00335	Higher
OV	Ovarian serous cystadenocarcinoma	296	0.07	0.233	NS
PAAD	Pancreatic adenocarcinoma	176	-0.046	0.547	NS
STAD	Stomach adenocarcinoma	406	-0.072	0.15	NS
UCEC	Uterine Corpus Endometrial Carcinoma	534	0.16	0.00021	Higher

Summary
Symbol	MGA
Name	MGA, MAX dimerization protein
Aliases	KIAA0518; MAD5; MXD5; FLJ12634; MAX gene associated; MAX dimerization protein 5; MAX gene-associated protein
Location	15q15
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	MGA
Name	MGA, MAX dimerization protein
Aliases	KIAA0518; MAD5; MXD5; FLJ12634; MAX gene associated; MAX dimerization protein 5; MAX gene-associated protein
Location	15q15
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for MGA.

Summary
Symbol	MGA
Name	MGA, MAX dimerization protein
Aliases	KIAA0518; MAD5; MXD5; FLJ12634; MAX gene associated; MAX dimerization protein 5; MAX gene-associated protein
Location	15q15
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining [ TOP ]
There is no record for MGA.