CR2Cancer

Summary
Symbol	SETD1A
Name	SET domain containing 1A
Aliases	KIAA0339; Set1; KMT2F; Set1A; SET domain-containing protein 1A; hSET1A; lysine N-methyltransferase 2F; set1/ ......
Location	16p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

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Domain

PF11764 COMPASS (Complex proteins associated with Set1p) component N
PF00076 RNA recognition motif. (a.k.a. RRM
PF00856 SET domain

Function

Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overlapping localization with SETD1B suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression.

Classification

Class	Modification	Substrate	Product	PubMed
Histone modification write	Histone methylation	H3K4	H3K4me	17355966

> Gene Ontology [ TOP ]
Biological Process	GO:0006479 protein methylation GO:0008213 protein alkylation GO:0016570 histone modification GO:0016571 histone methylation GO:0018022 peptidyl-lysine methylation GO:0018205 peptidyl-lysine modification GO:0019827 stem cell population maintenance GO:0032259 methylation GO:0034968 histone lysine methylation GO:0043414 macromolecule methylation GO:0051568 histone H3-K4 methylation GO:0061351 neural precursor cell proliferation GO:0072089 stem cell proliferation GO:0072091 regulation of stem cell proliferation GO:0098727 maintenance of cell number GO:2000177 regulation of neural precursor cell proliferation GO:2000179 positive regulation of neural precursor cell proliferation GO:2000648 positive regulation of stem cell proliferation
Molecular Function	GO:0003682 chromatin binding GO:0008013 beta-catenin binding GO:0008168 methyltransferase activity GO:0008170 N-methyltransferase activity GO:0008276 protein methyltransferase activity GO:0008757 S-adenosylmethionine-dependent methyltransferase activity GO:0016278 lysine N-methyltransferase activity GO:0016279 protein-lysine N-methyltransferase activity GO:0016741 transferase activity, transferring one-carbon groups GO:0018024 histone-lysine N-methyltransferase activity GO:0042054 histone methyltransferase activity GO:0042800 histone methyltransferase activity (H3-K4 specific) GO:1990188 euchromatin binding
Cellular Component	GO:0000785 chromatin GO:0000790 nuclear chromatin GO:0000791 euchromatin GO:0005719 nuclear euchromatin GO:0016604 nuclear body GO:0016607 nuclear speck GO:0034708 methyltransferase complex GO:0035097 histone methyltransferase complex GO:0044454 nuclear chromosome part GO:0048188 Set1C/COMPASS complex

> KEGG and Reactome Pathway [ TOP ]
KEGG	hsa00310 Lysine degradation
Reactome	R-HSA-3247509: Chromatin modifying enzymes R-HSA-4839726: Chromatin organization R-HSA-3214841: PKMTs methylate histone lysines

Summary
Symbol	SETD1A
Name	SET domain containing 1A
Aliases	KIAA0339; Set1; KMT2F; Set1A; SET domain-containing protein 1A; hSET1A; lysine N-methyltransferase 2F; set1/ ......
Location	16p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM5726266	c.3543C>T	p.P1181P	Substitution - coding silent	Skin
COSM970042	c.1925C>T	p.P642L	Substitution - Missense	Endometrium
COSM3113521	c.1926G>A	p.P642P	Substitution - coding silent	Stomach
COSM4642009	c.3771C>G	p.A1257A	Substitution - coding silent	Large_intestine
COSM394655	c.2031C>T	p.P677P	Substitution - coding silent	Lung
COSM4489072	c.3428C>T	p.P1143L	Substitution - Missense	Skin
COSM1377525	c.576_577delTG	p.V193fs*9	Deletion - Frameshift	Large_intestine
COSM126104	c.1733C>T	p.S578F	Substitution - Missense	Upper_aerodigestive_tract
COSM263602	c.3328G>A	p.E1110K	Substitution - Missense	Large_intestine
COSM5680016	c.5054A>G	p.K1685R	Substitution - Missense	Soft_tissue
COSM970036	c.527G>A	p.R176Q	Substitution - Missense	Endometrium
COSM5740625	c.3647C>T	p.S1216F	Substitution - Missense	Small_intestine
COSM4945388	c.3031A>T	p.S1011C	Substitution - Missense	Liver
COSM4975313	c.2551G>C	p.E851Q	Substitution - Missense	Oesophagus
COSM3508988	c.3007G>T	p.V1003L	Substitution - Missense	Skin
COSM5722439	c.1109A>T	p.Y370F	Substitution - Missense	Skin
COSM4934479	c.1774G>A	p.G592S	Substitution - Missense	Liver
COSM5923172	c.235C>T	p.P79S	Substitution - Missense	Skin
COSM4928982	c.994G>A	p.A332T	Substitution - Missense	Liver
COSM5038462	c.3969A>C	p.A1323A	Substitution - coding silent	Skin
COSM4517630	c.3872_3873CC>TT	p.P1291L	Substitution - Missense	Skin
COSM3113491	c.1013C>A	p.S338Y	Substitution - Missense	Large_intestine
COSM1478811	c.1246G>A	p.E416K	Substitution - Missense	Breast
COSM5722439	c.1109A>T	p.Y370F	Substitution - Missense	Skin
COSM4392165	c.344G>A	p.R115H	Substitution - Missense	Prostate
COSM1377537	c.3537G>A	p.P1179P	Substitution - coding silent	Stomach
COSM703234	c.115G>A	p.V39M	Substitution - Missense	Lung
COSM3737073	c.4511_4513delAGA	p.K1505delK	Deletion - In frame	Soft_tissue
COSM5722438	c.895C>T	p.R299W	Substitution - Missense	Skin
COSM970046	c.2123G>C	p.G708A	Substitution - Missense	Endometrium
COSM970049	c.2969G>A	p.R990Q	Substitution - Missense	Large_intestine
COSM4982208	c.2755G>A	p.E919K	Substitution - Missense	Oesophagus
COSM4501120	c.580C>T	p.P194S	Substitution - Missense	Skin
COSM1720387	c.3889C>T	p.L1297F	Substitution - Missense	Skin
COSM4509652	c.813C>A	p.T271T	Substitution - coding silent	Skin
COSM1724645	c.928_929insC	p.R311fs*51	Insertion - Frameshift	Skin
COSM4980540	c.1129C>T	p.Q377*	Substitution - Nonsense	Oesophagus
COSM145919	c.1109A>G	p.Y370C	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM340087	c.2119C>T	p.P707S	Substitution - Missense	Lung
COSM78472	c.5029G>C	p.D1677H	Substitution - Missense	Ovary
COSM4725144	c.3475C>T	p.P1159S	Substitution - Missense	Large_intestine
COSM5773401	c.3519C>T	p.I1173I	Substitution - coding silent	Breast
COSM5054850	c.3797G>A	p.R1266H	Substitution - Missense	Stomach
COSM5777900	c.4980C>T	p.I1660I	Substitution - coding silent	Breast
COSM3690710	c.3208C>T	p.R1070W	Substitution - Missense	Large_intestine
COSM1493627	c.1605G>A	p.G535G	Substitution - coding silent	Kidney
COSM1324488	c.3460C>G	p.P1154A	Substitution - Missense	Ovary
COSM1290511	c.5069A>C	p.D1690A	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4507599	c.750C>T	p.S250S	Substitution - coding silent	Skin
COSM2153183	c.131G>A	p.G44E	Substitution - Missense	Central_nervous_system
COSM1679027	c.4651G>A	p.A1551T	Substitution - Missense	Central_nervous_system
COSM273229	c.967G>A	p.A323T	Substitution - Missense	Large_intestine
COSM4494916	c.4427C>T	p.P1476L	Substitution - Missense	Skin
COSM4725141	c.2713G>A	p.E905K	Substitution - Missense	Large_intestine
COSM4834365	c.4506C>T	p.I1502I	Substitution - coding silent	Cervix
COSM376259	c.1386A>T	p.P462P	Substitution - coding silent	Lung
COSM4538107	c.2500G>A	p.A834T	Substitution - Missense	Skin
COSM126103	c.1472G>T	p.R491L	Substitution - Missense	Upper_aerodigestive_tract
COSM1744343	c.3580C>A	p.P1194T	Substitution - Missense	Biliary_tract
COSM4494916	c.4427C>T	p.P1476L	Substitution - Missense	Skin
COSM5759032	c.4134_4136delCAG	p.S1383delS	Deletion - In frame	Bone
COSM2153183	c.131G>A	p.G44E	Substitution - Missense	Central_nervous_system
COSM3508992	c.5115C>T	p.S1705S	Substitution - coding silent	Skin
COSM3712014	c.1280C>A	p.P427H	Substitution - Missense	Upper_aerodigestive_tract
COSM4477894	c.2194C>T	p.L732L	Substitution - coding silent	Skin
COSM970037	c.919G>T	p.D307Y	Substitution - Missense	Endometrium
COSM5384768	c.2929-1G>A	p.?	Unknown	Skin
COSM703226	c.3927G>C	p.T1309T	Substitution - coding silent	Lung
COSM4774332	c.3435A>C	p.P1145P	Substitution - coding silent	Stomach
COSM3508973	c.1142C>T	p.S381F	Substitution - Missense	Skin
COSM3817841	c.1254C>T	p.S418S	Substitution - coding silent	Breast
COSM4647919	c.3973G>A	p.A1325T	Substitution - Missense	Large_intestine
COSM6002316	c.97C>T	p.R33C	Substitution - Missense	Prostate
COSM3672238	c.4807C>A	p.R1603S	Substitution - Missense	Prostate
COSM5890939	c.3506C>T	p.S1169F	Substitution - Missense	Skin
COSM3508987	c.2961T>G	p.D987E	Substitution - Missense	Skin
COSM703232	c.1268A>T	p.Q423L	Substitution - Missense	Lung
COSM703229	c.2866C>T	p.R956C	Substitution - Missense	Lung
COSM126106	c.4915G>A	p.G1639S	Substitution - Missense	Upper_aerodigestive_tract
COSM4789608	c.4233G>A	p.P1411P	Substitution - coding silent	Liver
COSM3508991	c.4458C>T	p.P1486P	Substitution - coding silent	Skin
COSM5722438	c.895C>T	p.R299W	Substitution - Missense	Skin
COSM4607637	c.904G>T	p.E302*	Substitution - Nonsense	Adrenal_gland
COSM5913795	c.2129C>T	p.A710V	Substitution - Missense	Skin
COSM3113477	c.618C>T	p.G206G	Substitution - coding silent	Large_intestine
COSM703228	c.3800G>A	p.G1267E	Substitution - Missense	Lung
COSM135706	c.5072A>G	p.N1691S	Substitution - Missense	Skin
COSM4792832	c.2208G>A	p.G736G	Substitution - coding silent	Liver
COSM3113465	c.220delT	p.S75fs*19	Deletion - Frameshift	Large_intestine
COSM4610764	c.4861A>C	p.S1621R	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM970047	c.2323G>A	p.E775K	Substitution - Missense	Endometrium
COSM1377536	c.3449G>A	p.R1150H	Substitution - Missense	Large_intestine
COSM4060274	c.1248G>A	p.E416E	Substitution - coding silent	Stomach
COSM970041	c.1610G>T	p.G537V	Substitution - Missense	Endometrium
COSM3420946	c.2835C>T	p.D945D	Substitution - coding silent	Large_intestine
COSM5635340	c.4954A>G	p.N1652D	Substitution - Missense	Oesophagus
COSM4060268	c.119A>G	p.Y40C	Substitution - Missense	Stomach
COSM3508965	c.408C>T	p.G136G	Substitution - coding silent	Skin
COSM4725145	c.3947G>A	p.R1316Q	Substitution - Missense	Large_intestine
COSM5497420	c.523C>T	p.Q175*	Substitution - Nonsense	Biliary_tract
COSM1724646	c.3127_3129delTCC	p.S1058delS	Deletion - In frame	Skin
COSM3113521	c.1926G>A	p.P642P	Substitution - coding silent	Large_intestine
COSM4516074	c.1560_1561CC>TT	p.L521F	Substitution - Missense	Skin
COSM6002006	c.1663G>A	p.G555R	Substitution - Missense	Prostate
COSM1324491	c.674C>G	p.A225G	Substitution - Missense	Ovary
COSM3707009	c.1769G>A	p.R590Q	Substitution - Missense	Liver
COSM4474138	c.1899C>T	p.L633L	Substitution - coding silent	Skin
COSM5604835	c.1860C>T	p.S620S	Substitution - coding silent	Skin
COSM3113557	c.3236C>T	p.P1079L	Substitution - Missense	Biliary_tract
COSM1324490	c.3176A>G	p.E1059G	Substitution - Missense	Ovary
COSM5602270	c.362A>C	p.E121A	Substitution - Missense	Skin
COSM4595612	c.2689C>G	p.R897G	Substitution - Missense	Upper_aerodigestive_tract
COSM970050	c.3761C>T	p.A1254V	Substitution - Missense	Endometrium
COSM5732592	c.535T>C	p.Y179H	Substitution - Missense	Pancreas
COSM5621803	c.4011G>T	p.E1337D	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3937047	c.1054T>C	p.S352P	Substitution - Missense	Oesophagus
COSM5968484	c.4017C>A	p.P1339P	Substitution - coding silent	Genital_tract
COSM1609216	c.4254C>G	p.R1418R	Substitution - coding silent	Liver
COSM3817840	c.383A>C	p.H128P	Substitution - Missense	Breast
COSM4060275	c.1382G>A	p.R461H	Substitution - Missense	Stomach
COSM970035	c.217G>T	p.D73Y	Substitution - Missense	Endometrium
COSM107398	c.929C>T	p.S310F	Substitution - Missense	Skin
COSM4788872	c.1055C>G	p.S352C	Substitution - Missense	Liver
COSM362889	c.3119G>C	p.S1040T	Substitution - Missense	Lung
COSM4060276	c.2122G>A	p.G708S	Substitution - Missense	Stomach
COSM3508985	c.2586C>T	p.S862S	Substitution - coding silent	Skin
COSM3508986	c.2711C>T	p.S904F	Substitution - Missense	Skin
COSM3707011	c.2630C>T	p.A877V	Substitution - Missense	Liver
COSM417037	c.4312G>C	p.E1438Q	Substitution - Missense	Urinary_tract
COSM3719196	c.1145A>G	p.Y382C	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4060283	c.4037C>T	p.A1346V	Substitution - Missense	Stomach
COSM4060281	c.3849G>A	p.S1283S	Substitution - coding silent	Stomach
COSM4752071	c.2162C>T	p.P721L	Substitution - Missense	Stomach
COSM5384766	c.1846C>T	p.P616S	Substitution - Missense	Biliary_tract
COSM1377530	c.2115delC	p.G708fs*95	Deletion - Frameshift	Large_intestine
COSM3508989	c.3044C>T	p.S1015F	Substitution - Missense	Skin
COSM3690711	c.3338C>T	p.A1113V	Substitution - Missense	Large_intestine
COSM3741891	c.3141C>T	p.S1047S	Substitution - coding silent	Liver
COSM1301899	c.4739G>T	p.W1580L	Substitution - Missense	Urinary_tract
COSM3508973	c.1142C>T	p.S381F	Substitution - Missense	Skin
COSM4780076	c.3505T>G	p.S1169A	Substitution - Missense	Liver
COSM315106	c.4484G>T	p.R1495L	Substitution - Missense	Lung
COSM1377529	c.2049G>T	p.Q683H	Substitution - Missense	Large_intestine
COSM1709089	c.1903C>T	p.P635S	Substitution - Missense	Skin
COSM5658239	c.1305G>A	p.P435P	Substitution - coding silent	Soft_tissue
COSM4129001	c.994G>T	p.A332S	Substitution - Missense	Thyroid
COSM3707011	c.2630C>T	p.A877V	Substitution - Missense	Liver
COSM5886933	c.568C>T	p.P190S	Substitution - Missense	Skin
COSM293576	c.3643G>A	p.A1215T	Substitution - Missense	Large_intestine
COSM3734330	c.4433G>A	p.R1478H	Substitution - Missense	Pancreas
COSM3690945	c.3972C>T	p.P1324P	Substitution - coding silent	Large_intestine
COSM970036	c.527G>A	p.R176Q	Substitution - Missense	Biliary_tract
COSM970048	c.2358G>A	p.P786P	Substitution - coding silent	Endometrium
COSM3988434	c.49T>C	p.W17R	Substitution - Missense	Kidney
COSM1324492	c.639G>C	p.T213T	Substitution - coding silent	Ovary
COSM1377533	c.3039G>A	p.S1013S	Substitution - coding silent	Large_intestine
COSM3508984	c.2585C>T	p.S862F	Substitution - Missense	Skin
COSM1225341	c.935G>A	p.R312H	Substitution - Missense	Large_intestine
COSM140761	c.634G>T	p.E212*	Substitution - Nonsense	Skin
COSM3402286	c.1323T>C	p.G441G	Substitution - coding silent	Central_nervous_system
COSM3113499	c.1154G>A	p.R385H	Substitution - Missense	Large_intestine
COSM4788872	c.1055C>G	p.S352C	Substitution - Missense	Liver
COSM5567450	c.4650C>T	p.S1550S	Substitution - coding silent	Prostate
COSM1377527	c.1174delC	p.P393fs*104	Deletion - Frameshift	Large_intestine
COSM3508968	c.612C>T	p.F204F	Substitution - coding silent	Skin
COSM397515	c.2753C>T	p.A918V	Substitution - Missense	Lung
COSM263602	c.3328G>A	p.E1110K	Substitution - Missense	Large_intestine
COSM4725140	c.1678G>T	p.G560W	Substitution - Missense	Large_intestine
COSM5015370	c.680A>G	p.Y227C	Substitution - Missense	Kidney
COSM263602	c.3328G>A	p.E1110K	Substitution - Missense	Large_intestine
COSM703225	c.4838G>A	p.R1613H	Substitution - Missense	Lung
COSM5384770	c.4877G>A	p.R1626Q	Substitution - Missense	Skin
COSM1709088	c.1046C>T	p.S349L	Substitution - Missense	Skin
COSM349183	c.5082G>T	p.P1694P	Substitution - coding silent	Lung
COSM1324489	c.3199G>T	p.E1067*	Substitution - Nonsense	Ovary
COSM5985952	c.3032G>C	p.S1011T	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3888418	c.3311C>T	p.P1104L	Substitution - Missense	Skin
COSM118429	c.1743C>T	p.D581D	Substitution - coding silent	Ovary
COSM5722439	c.1109A>T	p.Y370F	Substitution - Missense	Skin
COSM5886932	c.569C>T	p.P190L	Substitution - Missense	Skin
COSM1724646	c.3127_3129delTCC	p.S1058delS	Deletion - In frame	Urinary_tract
COSM3113498	c.1133G>A	p.R378H	Substitution - Missense	Large_intestine
COSM4129002	c.3622C>A	p.R1208S	Substitution - Missense	Thyroid
COSM4432604	c.4660G>T	p.D1554Y	Substitution - Missense	Oesophagus
COSM6016150	c.224C>T	p.S75F	Substitution - Missense	Skin
COSM4789608	c.4233G>A	p.P1411P	Substitution - coding silent	Liver
COSM3690944	c.3713G>A	p.R1238H	Substitution - Missense	Large_intestine
COSM397516	c.4218A>C	p.P1406P	Substitution - coding silent	Lung
COSM1225342	c.2665C>T	p.R889W	Substitution - Missense	Large_intestine
COSM1749567	c.1733C>G	p.S578C	Substitution - Missense	Urinary_tract
COSM1128978	c.4240G>A	p.A1414T	Substitution - Missense	Prostate
COSM137642	c.1160C>T	p.A387V	Substitution - Missense	Skin
COSM5363424	c.1381C>T	p.R461C	Substitution - Missense	Large_intestine
COSM6002006	c.1663G>A	p.G555R	Substitution - Missense	Prostate
COSM3690942	c.3350G>T	p.R1117M	Substitution - Missense	Large_intestine
COSM5638645	c.5000T>C	p.V1667A	Substitution - Missense	Oesophagus
COSM3370398	c.4382A>G	p.N1461S	Substitution - Missense	Thyroid
COSM3508979	c.2021G>C	p.G674A	Substitution - Missense	Skin
COSM5500155	c.1719+10G>T	p.?	Unknown	Biliary_tract
COSM1377539	c.4372G>T	p.D1458Y	Substitution - Missense	Large_intestine
COSM3707008	c.1654G>C	p.A552P	Substitution - Missense	Liver
COSM315106	c.4484G>T	p.R1495L	Substitution - Missense	Soft_tissue
COSM3707010	c.2234G>A	p.R745Q	Substitution - Missense	Liver
COSM3508982	c.2102C>T	p.A701V	Substitution - Missense	Skin
COSM1582314	c.4712G>A	p.R1571Q	Substitution - Missense	Stomach
COSM347051	c.437G>C	p.R146P	Substitution - Missense	Lung
COSM3707012	c.2739T>A	p.R913R	Substitution - coding silent	Liver
COSM5002574	c.2002C>T	p.R668*	Substitution - Nonsense	Pancreas
COSM1265336	c.4387A>G	p.T1463A	Substitution - Missense	Oesophagus
COSM1749567	c.1733C>G	p.S578C	Substitution - Missense	Urinary_tract
COSM4060279	c.3129C>A	p.S1043S	Substitution - coding silent	Stomach
COSM4060271	c.932G>A	p.R311H	Substitution - Missense	Stomach
COSM4060278	c.3076G>A	p.E1026K	Substitution - Missense	Stomach
COSM3734330	c.4433G>A	p.R1478H	Substitution - Missense	Pancreas
COSM3113545	c.2717C>T	p.A906V	Substitution - Missense	Large_intestine
COSM5668041	c.597C>T	p.A199A	Substitution - coding silent	Soft_tissue
COSM1225343	c.2233C>T	p.R745W	Substitution - Missense	Large_intestine
COSM1377530	c.2115delC	p.G708fs*95	Deletion - Frameshift	Large_intestine
COSM4060282	c.3951C>A	p.P1317P	Substitution - coding silent	Stomach
COSM5604834	c.815C>T	p.P272L	Substitution - Missense	Skin
COSM1709090	c.5080C>T	p.P1694S	Substitution - Missense	Skin
COSM1377530	c.2115delC	p.G708fs*95	Deletion - Frameshift	Large_intestine
COSM3113552	c.2987C>A	p.T996N	Substitution - Missense	Large_intestine
COSM1377526	c.801C>A	p.S267S	Substitution - coding silent	Large_intestine
COSM4060284	c.4330C>T	p.R1444W	Substitution - Missense	Stomach
COSM3937048	c.1860C>A	p.S620S	Substitution - coding silent	Oesophagus
COSM5384766	c.1846C>T	p.P616S	Substitution - Missense	Skin
COSM5728417	c.3098C>T	p.S1033F	Substitution - Missense	Skin
COSM1377534	c.3141C>G	p.S1047S	Substitution - coding silent	Skin
COSM4060285	c.4625G>A	p.R1542Q	Substitution - Missense	Stomach
COSM3817842	c.1951C>G	p.P651A	Substitution - Missense	Breast
COSM225371	c.3575C>T	p.P1192L	Substitution - Missense	Skin
COSM970043	c.1962G>A	p.P654P	Substitution - coding silent	Endometrium
COSM126105	c.2065C>T	p.R689W	Substitution - Missense	Upper_aerodigestive_tract
COSM4913489	c.2003G>T	p.R668L	Substitution - Missense	Liver
COSM4725147	c.4615G>A	p.E1539K	Substitution - Missense	Large_intestine
COSM3113476	c.541G>C	p.E181Q	Substitution - Missense	Lung
COSM5722439	c.1109A>T	p.Y370F	Substitution - Missense	Skin
COSM5484019	c.1041C>A	p.S347S	Substitution - coding silent	Large_intestine
COSM4986330	c.2278C>T	p.P760S	Substitution - Missense	Soft_tissue
COSM3508980	c.2023G>A	p.G675R	Substitution - Missense	Skin
COSM5929683	c.1627C>T	p.P543S	Substitution - Missense	Skin
COSM4060269	c.207C>T	p.S69S	Substitution - coding silent	Stomach
COSM397516	c.4218A>C	p.P1406P	Substitution - coding silent	Soft_tissue
COSM1377530	c.2115delC	p.G708fs*95	Deletion - Frameshift	Biliary_tract
COSM3508981	c.2085G>C	p.Q695H	Substitution - Missense	Skin
COSM703233	c.814C>T	p.P272S	Substitution - Missense	Lung
COSM4917352	c.1586A>G	p.E529G	Substitution - Missense	Liver
COSM3508966	c.465C>T	p.L155L	Substitution - coding silent	Skin
COSM4060273	c.1174C>A	p.P392T	Substitution - Missense	Stomach
COSM4725142	c.2842C>T	p.R948*	Substitution - Nonsense	Large_intestine
COSM3932332	c.4352T>G	p.L1451R	Substitution - Missense	Urinary_tract
COSM5595297	c.3507C>T	p.S1169S	Substitution - coding silent	Skin
COSM4390534	c.3785C>A	p.T1262N	Substitution - Missense	Urinary_tract
COSM1749566	c.513C>G	p.I171M	Substitution - Missense	Urinary_tract
COSM1563138	c.4383C>T	p.N1461N	Substitution - coding silent	Large_intestine
COSM1377537	c.3537G>A	p.P1179P	Substitution - coding silent	Large_intestine
COSM1709087	c.776C>T	p.S259F	Substitution - Missense	Skin
COSM4725146	c.4594G>A	p.V1532M	Substitution - Missense	Large_intestine
COSM3508991	c.4458C>T	p.P1486P	Substitution - coding silent	Skin
COSM1377534	c.3141C>G	p.S1047S	Substitution - coding silent	Large_intestine
COSM3508971	c.946G>T	p.A316S	Substitution - Missense	Skin
COSM1324487	c.4245C>G	p.Y1415*	Substitution - Nonsense	Ovary
COSM5621802	c.503A>T	p.Q168L	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM970052	c.5026G>A	p.V1676M	Substitution - Missense	Endometrium
COSM5787476	c.4409-10C>T	p.?	Unknown	Breast
COSM1377538	c.3576C>A	p.P1192P	Substitution - coding silent	Large_intestine
COSM5462531	c.4508G>A	p.S1503N	Substitution - Missense	Large_intestine
COSM241570	c.2456C>G	p.A819G	Substitution - Missense	Prostate
COSM1225344	c.4337C>T	p.T1446M	Substitution - Missense	Large_intestine
COSM5925884	c.1216C>T	p.P406S	Substitution - Missense	Skin
COSM4949919	c.719G>A	p.G240D	Substitution - Missense	Liver
COSM3508970	c.931C>T	p.R311C	Substitution - Missense	Skin
COSM3707012	c.2739T>A	p.R913R	Substitution - coding silent	Liver
COSM118429	c.1743C>T	p.D581D	Substitution - coding silent	Stomach
COSM4941755	c.1456A>G	p.S486G	Substitution - Missense	Liver
COSM4060277	c.3000G>C	p.E1000D	Substitution - Missense	Stomach
COSM970038	c.1056T>G	p.S352S	Substitution - coding silent	Endometrium
COSM3113510	c.1511C>T	p.S504F	Substitution - Missense	Skin
COSM3690943	c.3688C>T	p.R1230W	Substitution - Missense	Large_intestine
COSM970036	c.527G>A	p.R176Q	Substitution - Missense	Large_intestine
COSM3508974	c.1212C>T	p.R404R	Substitution - coding silent	Skin
COSM5384764	c.224_225CC>TT	p.S75F	Substitution - Missense	Skin
COSM1377531	c.2435G>T	p.R812L	Substitution - Missense	Large_intestine
COSM4725145	c.3947G>A	p.R1316Q	Substitution - Missense	Prostate
COSM4725137	c.1157G>A	p.R386Q	Substitution - Missense	Large_intestine
COSM970045	c.2035T>C	p.S679P	Substitution - Missense	Endometrium
COSM3508977	c.1931C>T	p.P644L	Substitution - Missense	Skin
COSM4792832	c.2208G>A	p.G736G	Substitution - coding silent	Liver
COSM4490391	c.3632C>T	p.P1211L	Substitution - Missense	Skin
COSM107398	c.929C>T	p.S310F	Substitution - Missense	Skin
COSM4515881	c.1398_1399CC>TT	p.R467C	Substitution - Missense	Skin
COSM3690941	c.1986C>A	p.S662S	Substitution - coding silent	Large_intestine
COSM3957484	c.1549A>G	p.S517G	Substitution - Missense	Lung
COSM2149922	c.4627_4628delCT	p.L1543fs*13	Deletion - Frameshift	Central_nervous_system
COSM5985385	c.727T>C	p.C243R	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1316596	c.2936A>G	p.E979G	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4060272	c.1079G>A	p.R360H	Substitution - Missense	Stomach
COSM3988435	c.1223C>A	p.S408Y	Substitution - Missense	Kidney
COSM5722438	c.895C>T	p.R299W	Substitution - Missense	Skin
COSM5431545	c.4943G>A	p.C1648Y	Substitution - Missense	Oesophagus
COSM355064	c.2690G>A	p.R897Q	Substitution - Missense	Lung
COSM3113566	c.3601C>T	p.R1201W	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3957485	c.2289A>T	p.S763S	Substitution - coding silent	Lung
COSM4510456	c.837C>T	p.T279T	Substitution - coding silent	Skin
COSM1709086	c.196C>T	p.H66Y	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5759547	c.3809C>T	p.A1270V	Substitution - Missense	Bone
COSM970049	c.2969G>A	p.R990Q	Substitution - Missense	Endometrium
COSM1478810	c.789C>T	p.F263F	Substitution - coding silent	Breast
COSM349183	c.5082G>T	p.P1694P	Substitution - coding silent	Oesophagus
COSM5001428	c.3529C>A	p.P1177T	Substitution - Missense	Pancreas
COSM3707010	c.2234G>A	p.R745Q	Substitution - Missense	Liver
COSM4885231	c.3476C>A	p.P1159H	Substitution - Missense	Upper_aerodigestive_tract
COSM703230	c.2741C>T	p.P914L	Substitution - Missense	Lung
COSM970039	c.1104G>A	p.A368A	Substitution - coding silent	Endometrium
COSM3508975	c.1282C>T	p.P428S	Substitution - Missense	Skin
COSM1609216	c.4254C>G	p.R1418R	Substitution - coding silent	Liver
COSM471652	c.2175C>G	p.A725A	Substitution - coding silent	Kidney
COSM970051	c.4676A>G	p.K1559R	Substitution - Missense	Endometrium
COSM703231	c.2040C>T	p.F680F	Substitution - coding silent	Lung
COSM435144	c.1950T>A	p.P650P	Substitution - coding silent	Breast
COSM1709086	c.196C>T	p.H66Y	Substitution - Missense	Skin
COSM3508972	c.1078C>T	p.R360C	Substitution - Missense	Skin
COSM5722438	c.895C>T	p.R299W	Substitution - Missense	Skin
COSM1189256	c.3532G>T	p.A1178S	Substitution - Missense	Lung
COSM970044	c.1992G>A	p.E664E	Substitution - coding silent	Endometrium
COSM3508976	c.1303C>T	p.P435S	Substitution - Missense	Skin
COSM471655	c.3862C>A	p.R1288S	Substitution - Missense	Kidney
COSM3113583	c.4602C>T	p.S1534S	Substitution - coding silent	Oesophagus
COSM4884102	c.4551G>T	p.S1517S	Substitution - coding silent	Upper_aerodigestive_tract
COSM5574220	c.1783C>T	p.P595S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5384767	c.2352C>T	p.T784T	Substitution - coding silent	Skin
COSM5440487	c.4230A>C	p.P1410P	Substitution - coding silent	Oesophagus
COSM376258	c.280A>G	p.K94E	Substitution - Missense	Lung
COSM1749566	c.513C>G	p.I171M	Substitution - Missense	Urinary_tract
COSM3707009	c.1769G>A	p.R590Q	Substitution - Missense	Liver
COSM5574218	c.1832C>T	p.P611L	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM215644	c.1787C>T	p.P596L	Substitution - Missense	Central_nervous_system
COSM3707008	c.1654G>C	p.A552P	Substitution - Missense	Liver
COSM3508969	c.731C>T	p.S244F	Substitution - Missense	Skin
COSM4387728	c.2517C>T	p.N839N	Substitution - coding silent	Pancreas
COSM4490948	c.3719C>T	p.T1240I	Substitution - Missense	Skin
COSM3402287	c.1931C>G	p.P644R	Substitution - Missense	Central_nervous_system
COSM145919	c.1109A>G	p.Y370C	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4725136	c.653G>A	p.R218H	Substitution - Missense	Large_intestine
COSM4767954	c.1519G>A	p.A507T	Substitution - Missense	Biliary_tract
COSM6006145	c.1918G>C	p.G640R	Substitution - Missense	Small_intestine
COSM3508978	c.1951C>T	p.P651S	Substitution - Missense	Skin
COSM4725143	c.3143C>T	p.S1048L	Substitution - Missense	Large_intestine
COSM5888301	c.2929-6C>T	p.?	Unknown	Upper_aerodigestive_tract
COSM323276	c.764A>C	p.D255A	Substitution - Missense	Lung
COSM4538033	c.2496G>A	p.E832E	Substitution - coding silent	Skin
COSM398477	c.4347G>T	p.R1449R	Substitution - coding silent	Lung
COSM4495979	c.4652C>T	p.A1551V	Substitution - Missense	Skin
COSM1377534	c.3141C>G	p.S1047S	Substitution - coding silent	Prostate
COSM3113521	c.1926G>A	p.P642P	Substitution - coding silent	Oesophagus
COSM4889039	c.928T>C	p.S310P	Substitution - Missense	Upper_aerodigestive_tract
COSM1679025	c.122G>A	p.R41H	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5384769	c.3234C>T	p.S1078S	Substitution - coding silent	Skin
COSM4970220	c.2626G>T	p.E876*	Substitution - Nonsense	Central_nervous_system
COSM4515667	c.1241_1242CC>TT	p.P414L	Substitution - Missense	Skin
COSM4794469	c.1038G>A	p.S346S	Substitution - coding silent	Liver
COSM1377534	c.3141C>G	p.S1047S	Substitution - coding silent	Large_intestine
COSM3794807	c.4995G>A	p.K1665K	Substitution - coding silent	Urinary_tract
COSM3712014	c.1280C>A	p.P427H	Substitution - Missense	Upper_aerodigestive_tract
COSM5984476	c.279G>A	p.L93L	Substitution - coding silent	Upper_aerodigestive_tract
COSM3690709	c.3033C>T	p.S1011S	Substitution - coding silent	Large_intestine
COSM1720387	c.3889C>T	p.L1297F	Substitution - Missense	Skin
COSM435143	c.69C>T	p.I23I	Substitution - coding silent	Breast
COSM4426229	c.3012G>A	p.S1004S	Substitution - coding silent	Oesophagus
COSM970053	c.5086C>T	p.L1696L	Substitution - coding silent	Endometrium
COSM1377528	c.1926_1927insC	p.E645fs*1	Insertion - Frameshift	Large_intestine
COSM1709088	c.1046C>T	p.S349L	Substitution - Missense	Skin
COSM4768304	c.141C>T	p.F47F	Substitution - coding silent	Biliary_tract
COSM1377534	c.3141C>G	p.S1047S	Substitution - coding silent	Stomach
COSM5054849	c.164T>C	p.I55T	Substitution - Missense	Stomach
COSM4060280	c.3144G>A	p.S1048S	Substitution - coding silent	Stomach
COSM4794469	c.1038G>A	p.S346S	Substitution - coding silent	Liver
COSM5985386	c.730T>C	p.S244P	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1679027	c.4651G>A	p.A1551T	Substitution - Missense	Central_nervous_system
COSM5706112	c.884C>T	p.S295F	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM970040	c.1421A>G	p.E474G	Substitution - Missense	Endometrium
COSM5384765	c.351C>T	p.Y117Y	Substitution - coding silent	Skin
COSM3948488	c.3802C>T	p.L1268L	Substitution - coding silent	Ovary
COSM3113592	c.4935C>T	p.I1645I	Substitution - coding silent	Large_intestine
COSM5634295	c.365A>T	p.E122V	Substitution - Missense	Oesophagus
COSM703227	c.3883C>T	p.H1295Y	Substitution - Missense	Lung
COSM1679026	c.1123C>T	p.R375C	Substitution - Missense	Ovary
COSM3737073	c.4511_4513delAGA	p.K1505delK	Deletion - In frame	Soft_tissue
COSM3772196	c.3772G>A	p.D1258N	Substitution - Missense	Pancreas
COSM4630201	c.3694C>T	p.R1232W	Substitution - Missense	Large_intestine
COSM164274	c.1072C>T	p.Q358*	Substitution - Nonsense	Breast
COSM970049	c.2969G>A	p.R990Q	Substitution - Missense	Breast
COSM5074342	c.1039_1041delTCC	p.S357delS	Deletion - In frame	Large_intestine
COSM4949919	c.719G>A	p.G240D	Substitution - Missense	Liver
COSM107398	c.929C>T	p.S310F	Substitution - Missense	Skin
COSM4725139	c.1499G>A	p.R500H	Substitution - Missense	Large_intestine
COSM4151315	c.1607A>G	p.H536R	Substitution - Missense	Kidney
COSM5493422	c.4514_4516delAGG	p.E1506delE	Deletion - In frame	Biliary_tract
COSM5574219	c.1211G>A	p.R404H	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5980968	c.4073G>A	p.R1358Q	Substitution - Missense	Upper_aerodigestive_tract
COSM471654	c.3198G>A	p.E1066E	Substitution - coding silent	Kidney
COSM4725138	c.1188T>G	p.P396P	Substitution - coding silent	Large_intestine
COSM4602565	c.2416A>G	p.M806V	Substitution - Missense	Upper_aerodigestive_tract
COSM1377530	c.2115delC	p.G708fs*95	Deletion - Frameshift	Large_intestine
COSM3508983	c.2390T>A	p.M797K	Substitution - Missense	Skin
COSM3508990	c.3131C>T	p.S1044F	Substitution - Missense	Skin
COSM80508	c.3282G>T	p.V1094V	Substitution - coding silent	Ovary
COSM3508969	c.731C>T	p.S244F	Substitution - Missense	Skin
COSM268338	c.2290G>C	p.V764L	Substitution - Missense	Large_intestine
COSM3402285	c.704G>A	p.G235D	Substitution - Missense	Central_nervous_system

> Text Mining based Variations [ TOP ]
There is no record for SETD1A.

Summary
Symbol	SETD1A
Name	SET domain containing 1A
Aliases	KIAA0339; Set1; KMT2F; Set1A; SET domain-containing protein 1A; hSET1A; lysine N-methyltransferase 2F; set1/ ......
Location	16p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

[ TOP ]

Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant
O15047	464	S	Phosphoserine	-	Yes	p.S464F (cancer: LUAD)
O15047	508	S	Phosphoserine	-	No	None detected
O15047	565	S	Phosphoserine	-	No	None detected
O15047	915	S	Phosphoserine	-	No	None detected
O15047	1103	S	Phosphoserine	-	No	None detected

Summary
Symbol	SETD1A
Name	SET domain containing 1A
Aliases	KIAA0339; Set1; KMT2F; Set1A; SET domain-containing protein 1A; hSET1A; lysine N-methyltransferase 2F; set1/ ......
Location	16p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	5.421	5.675	0.276	0.00859	NS
BRCA	Breast invasive carcinoma	112	1100	5.314	5.606	0.321	1.54e-14	NS
CESC	Cervical and endocervical cancers	3	306	5.655	5.725	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	5.171	5.544	0.333	0.000281	NS
ESCA	Esophageal carcinoma	11	185	6.015	6.299	0.266	0.0756	NS
GBM	Glioblastoma multiforme	5	166	5.531	5.288	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	5.25	5.553	0.283	3.43e-05	NS
KIRC	Kidney renal clear cell carcinoma	72	534	4.939	5.269	0.364	2.49e-10	NS
KIRP	Kidney renal papillary cell carcinoma	32	291	5.363	5.894	0.541	8.59e-12	NS
LAML	Acute Myeloid Leukemia	0	173	NA	6.461	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	5.795	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	4.377	4.706	0.296	1.06e-05	NS
LUAD	Lung adenocarcinoma	59	517	5.251	5.501	0.352	2.33e-06	NS
LUSC	Lung squamous cell carcinoma	51	501	5.169	5.612	0.425	9.04e-07	NS
OV	Ovarian serous cystadenocarcinoma	0	307	NA	6.34	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	5.371	5.354	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	5.518	5.613	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	5.378	5.447	0.112	0.0159	NS
READ	Rectum adenocarcinoma	10	167	5.177	5.642	0.557	0.00271	NS
SARC	Sarcoma	2	263	5.053	5.735	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	5.237	5.881	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	5.897	6.026	0.229	0.0114	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	6.478	NA	NA	NA
THCA	Thyroid carcinoma	59	509	5.497	5.539	0.068	0.085	NS
THYM	Thymoma	2	120	6.339	6.123	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	5.804	5.884	0.047	0.626	NS

> Cancer Cell Line Encyclopedia (CCLE)

[ TOP ]

Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	5.7
Autonomic ganglia	CHP212	5.3
Autonomic ganglia	IMR32	5.9
Autonomic ganglia	KELLY	5.7
Autonomic ganglia	KPNRTBM1	5.6
Autonomic ganglia	KPNSI9S	5.4
Autonomic ganglia	KPNYN	6.1
Autonomic ganglia	MHHNB11	5.9
Autonomic ganglia	NB1	5.7
Autonomic ganglia	NH6	5.5
Autonomic ganglia	SHSY5Y	5.7
Autonomic ganglia	SIMA	5.8
Autonomic ganglia	SKNAS	5.6
Autonomic ganglia	SKNBE2	5.8
Autonomic ganglia	SKNDZ	5.7
Autonomic ganglia	SKNFI	5.4
Autonomic ganglia	SKNSH	5.3
Biliary tract	HUCCT1	5.2
Biliary tract	HUH28	5.7
Biliary tract	SNU1079	5.4
Biliary tract	SNU1196	5.6
Biliary tract	SNU245	5.8
Biliary tract	SNU308	6
Biliary tract	SNU478	5.2
Bone	143B	6.4
Bone	A673	5.7
Bone	CADOES1	5.4
Bone	CAL78	5.2
Bone	G292CLONEA141B1	5.5
Bone	HOS	5.7
Bone	HS706T	5.1
Bone	HS737T	5.1
Bone	HS819T	6.4
Bone	HS821T	5
Bone	HS822T	5.3
Bone	HS863T	5
Bone	HS870T	5.3
Bone	HS888T	5
Bone	MG63	6
Bone	MHHES1	5.7
Bone	OUMS27	5.6
Bone	RDES	5.5
Bone	SJSA1	5
Bone	SKES1	5.6
Bone	SKNMC	6
Bone	SW1353	5.5
Bone	T173	4.8
Bone	TC71	6
Bone	U2OS	5.3
Breast	AU565	5.2
Breast	BT20	5.5
Breast	BT474	5.4
Breast	BT483	5.4
Breast	BT549	5.8
Breast	CAL120	5.5
Breast	CAL148	5.8
Breast	CAL51	5.9
Breast	CAL851	4.9
Breast	CAMA1	5.8
Breast	DU4475	5.6
Breast	EFM192A	5.5
Breast	EFM19	5.7
Breast	EVSAT	5.4
Breast	HCC1143	6.2
Breast	HCC1187	5.1
Breast	HCC1395	5.7
Breast	HCC1419	5.5
Breast	HCC1428	5.6
Breast	HCC1500	5.3
Breast	HCC1569	5.4
Breast	HCC1599	5.5
Breast	HCC1806	5.7
Breast	HCC1937	5.7
Breast	HCC1954	5.2
Breast	HCC202	5.9
Breast	HCC2157	5.6
Breast	HCC2218	5.5
Breast	HCC38	5.6
Breast	HCC70	6.4
Breast	HDQP1	5.3
Breast	HMC18	5.6
Breast	HS274T	5
Breast	HS281T	5.4
Breast	HS343T	5.2
Breast	HS578T	5.4
Breast	HS606T	4.9
Breast	HS739T	5.1
Breast	HS742T	4.5
Breast	JIMT1	5.4
Breast	KPL1	5.5
Breast	MCF7	5.4
Breast	MDAMB134VI	5
Breast	MDAMB157	5.4
Breast	MDAMB175VII	5.7
Breast	MDAMB231	5.2
Breast	MDAMB361	5.2
Breast	MDAMB415	5.9
Breast	MDAMB436	5.8
Breast	MDAMB453	5.8
Breast	MDAMB468	5.1
Breast	SKBR3	5.3
Breast	T47D	5.7
Breast	UACC812	5.9
Breast	UACC893	5.9
Breast	YMB1	5.6
Breast	ZR751	5.2
Breast	ZR7530	5.6
Central nervous system	1321N1	5.3
Central nervous system	42MGBA	5.4
Central nervous system	8MGBA	5.5
Central nervous system	A172	5.3
Central nervous system	AM38	5.4
Central nervous system	BECKER	5.7
Central nervous system	CAS1	5.4
Central nervous system	CCFSTTG1	5.7
Central nervous system	D283MED	5.5
Central nervous system	D341MED	5.9
Central nervous system	DAOY	5.2
Central nervous system	DBTRG05MG	4.8
Central nervous system	DKMG	5
Central nervous system	GAMG	4.9
Central nervous system	GB1	6.1
Central nervous system	GI1	5.1
Central nervous system	GMS10	5.3
Central nervous system	GOS3	5.3
Central nervous system	H4	5.1
Central nervous system	HS683	5.4
Central nervous system	KALS1	5.4
Central nervous system	KG1C	5.8
Central nervous system	KNS42	5.1
Central nervous system	KNS60	5.5
Central nervous system	KNS81	5.3
Central nervous system	KS1	5.2
Central nervous system	LN18	5.4
Central nervous system	LN229	5.2
Central nervous system	M059K	5.1
Central nervous system	MOGGCCM	5.1
Central nervous system	MOGGUVW	5.4
Central nervous system	NMCG1	5.7
Central nervous system	ONS76	5.9
Central nervous system	SF126	5.5
Central nervous system	SF295	5.5
Central nervous system	SNB19	5.1
Central nervous system	SNU1105	4.9
Central nervous system	SNU201	5.2
Central nervous system	SNU466	5
Central nervous system	SNU489	5.5
Central nervous system	SNU626	5.2
Central nervous system	SNU738	5.6
Central nervous system	SW1088	5.6
Central nervous system	SW1783	5
Central nervous system	T98G	5.3
Central nervous system	TM31	5.7
Central nervous system	U118MG	6.7
Central nervous system	U138MG	5.7
Central nervous system	U251MG	4.9
Central nervous system	U87MG	5
Central nervous system	YH13	5.4
Central nervous system	YKG1	5.3
Endometrium	AN3CA	5.5
Endometrium	COLO684	5.8
Endometrium	EFE184	6.1
Endometrium	EN	5
Endometrium	ESS1	5.5
Endometrium	HEC108	6
Endometrium	HEC151	5.9
Endometrium	HEC1A	5.2
Endometrium	HEC1B	5.7
Endometrium	HEC251	5.3
Endometrium	HEC265	5.6
Endometrium	HEC50B	5.4
Endometrium	HEC59	5
Endometrium	HEC6	5.9
Endometrium	ISHIKAWAHERAKLIO02ER	5.5
Endometrium	JHUEM1	5.4
Endometrium	JHUEM2	6.1
Endometrium	JHUEM3	5.5
Endometrium	KLE	5.4
Endometrium	MFE280	5.2
Endometrium	MFE296	5.6
Endometrium	MFE319	5.8
Endometrium	RL952	5.5
Endometrium	SNGM	5.5
Endometrium	SNU1077	6.2
Endometrium	SNU685	5.8
Endometrium	TEN	5.7
Haematopoietic and lymphoid	697	6
Haematopoietic and lymphoid	A3KAW	5.7
Haematopoietic and lymphoid	A4FUK	6
Haematopoietic and lymphoid	ALLSIL	6.3
Haematopoietic and lymphoid	AML193	6.3
Haematopoietic and lymphoid	AMO1	5.7
Haematopoietic and lymphoid	BCP1	5.9
Haematopoietic and lymphoid	BDCM	5.7
Haematopoietic and lymphoid	BL41	6.7
Haematopoietic and lymphoid	BL70	6.4
Haematopoietic and lymphoid	BV173	5.9
Haematopoietic and lymphoid	CA46	5.9
Haematopoietic and lymphoid	CI1	6.4
Haematopoietic and lymphoid	CMK115	5.8
Haematopoietic and lymphoid	CMK86	6.9
Haematopoietic and lymphoid	CMK	6
Haematopoietic and lymphoid	CMLT1	5.6
Haematopoietic and lymphoid	COLO775	6.9
Haematopoietic and lymphoid	DAUDI	5.7
Haematopoietic and lymphoid	DB	5.6
Haematopoietic and lymphoid	DEL	5.2
Haematopoietic and lymphoid	DND41	5.9
Haematopoietic and lymphoid	DOHH2	6.4
Haematopoietic and lymphoid	EB1	5.6
Haematopoietic and lymphoid	EB2	5.5
Haematopoietic and lymphoid	EHEB	5.1
Haematopoietic and lymphoid	EJM	6.1
Haematopoietic and lymphoid	EM2	6.2
Haematopoietic and lymphoid	EOL1	6
Haematopoietic and lymphoid	F36P	5.6
Haematopoietic and lymphoid	GA10	6
Haematopoietic and lymphoid	GDM1	5.6
Haematopoietic and lymphoid	GRANTA519	5.9
Haematopoietic and lymphoid	HDLM2	5.5
Haematopoietic and lymphoid	HDMYZ	5.1
Haematopoietic and lymphoid	HEL9217	5.7
Haematopoietic and lymphoid	HEL	5.6
Haematopoietic and lymphoid	HH	5.9
Haematopoietic and lymphoid	HL60	6.5
Haematopoietic and lymphoid	HPBALL	6.2
Haematopoietic and lymphoid	HS604T	5.1
Haematopoietic and lymphoid	HS611T	5.8
Haematopoietic and lymphoid	HS616T	5.5
Haematopoietic and lymphoid	HS751T	4.7
Haematopoietic and lymphoid	HT	6.3
Haematopoietic and lymphoid	HTK	5.5
Haematopoietic and lymphoid	HUNS1	5.5
Haematopoietic and lymphoid	HUT102	5.6
Haematopoietic and lymphoid	HUT78	5.8
Haematopoietic and lymphoid	JEKO1	6.4
Haematopoietic and lymphoid	JK1	5.8
Haematopoietic and lymphoid	JM1	5.9
Haematopoietic and lymphoid	JURKAT	5.1
Haematopoietic and lymphoid	JURLMK1	5.9
Haematopoietic and lymphoid	JVM2	5.4
Haematopoietic and lymphoid	JVM3	5.5
Haematopoietic and lymphoid	K562	5.4
Haematopoietic and lymphoid	KARPAS299	5.9
Haematopoietic and lymphoid	KARPAS422	6
Haematopoietic and lymphoid	KARPAS620	6.2
Haematopoietic and lymphoid	KASUMI1	5.3
Haematopoietic and lymphoid	KASUMI2	6.1
Haematopoietic and lymphoid	KASUMI6	5.8
Haematopoietic and lymphoid	KCL22	5.5
Haematopoietic and lymphoid	KE37	6.1
Haematopoietic and lymphoid	KE97	5.5
Haematopoietic and lymphoid	KG1	5.8
Haematopoietic and lymphoid	KHM1B	5.6
Haematopoietic and lymphoid	KIJK	5.4
Haematopoietic and lymphoid	KMH2	6
Haematopoietic and lymphoid	KMM1	6
Haematopoietic and lymphoid	KMS11	6.1
Haematopoietic and lymphoid	KMS12BM	5.9
Haematopoietic and lymphoid	KMS18	5.8
Haematopoietic and lymphoid	KMS20	6.1
Haematopoietic and lymphoid	KMS21BM	5.3
Haematopoietic and lymphoid	KMS26	5.6
Haematopoietic and lymphoid	KMS27	5.7
Haematopoietic and lymphoid	KMS28BM	5.4
Haematopoietic and lymphoid	KMS34	5.7
Haematopoietic and lymphoid	KO52	5.9
Haematopoietic and lymphoid	KOPN8	5.8
Haematopoietic and lymphoid	KU812	5.9
Haematopoietic and lymphoid	KYO1	5.6
Haematopoietic and lymphoid	L1236	5.4
Haematopoietic and lymphoid	L363	5.8
Haematopoietic and lymphoid	L428	5.8
Haematopoietic and lymphoid	L540	5.8
Haematopoietic and lymphoid	LAMA84	5.9
Haematopoietic and lymphoid	LOUCY	5.7
Haematopoietic and lymphoid	LP1	6.1
Haematopoietic and lymphoid	M07E	6.1
Haematopoietic and lymphoid	MC116	5.6
Haematopoietic and lymphoid	ME1	6.1
Haematopoietic and lymphoid	MEC1	5.5
Haematopoietic and lymphoid	MEC2	6.2
Haematopoietic and lymphoid	MEG01	5.9
Haematopoietic and lymphoid	MHHCALL2	6
Haematopoietic and lymphoid	MHHCALL3	5.9
Haematopoietic and lymphoid	MHHCALL4	6.2
Haematopoietic and lymphoid	MINO	6.3
Haematopoietic and lymphoid	MJ	5.5
Haematopoietic and lymphoid	MM1S	5.7
Haematopoietic and lymphoid	MOLM13	5.4
Haematopoietic and lymphoid	MOLM16	6.4
Haematopoietic and lymphoid	MOLM6	5.6
Haematopoietic and lymphoid	MOLP2	5.8
Haematopoietic and lymphoid	MOLP8	5.3
Haematopoietic and lymphoid	MOLT13	5.9
Haematopoietic and lymphoid	MOLT16	5.6
Haematopoietic and lymphoid	MOLT4	5.8
Haematopoietic and lymphoid	MONOMAC1	5.7
Haematopoietic and lymphoid	MONOMAC6	5.8
Haematopoietic and lymphoid	MOTN1	5.6
Haematopoietic and lymphoid	MUTZ5	5.9
Haematopoietic and lymphoid	MV411	6.1
Haematopoietic and lymphoid	NALM19	6.2
Haematopoietic and lymphoid	NALM1	5.8
Haematopoietic and lymphoid	NALM6	6.1
Haematopoietic and lymphoid	NAMALWA	6.7
Haematopoietic and lymphoid	NB4	6.4
Haematopoietic and lymphoid	NCIH929	5.7
Haematopoietic and lymphoid	NCO2	5.3
Haematopoietic and lymphoid	NOMO1	5.7
Haematopoietic and lymphoid	NUDHL1	5.8
Haematopoietic and lymphoid	NUDUL1	6.2
Haematopoietic and lymphoid	OCIAML2	5.9
Haematopoietic and lymphoid	OCIAML3	6
Haematopoietic and lymphoid	OCIAML5	5.7
Haematopoietic and lymphoid	OCILY10	5.7
Haematopoietic and lymphoid	OCILY19	6.1
Haematopoietic and lymphoid	OCILY3	6
Haematopoietic and lymphoid	OCIM1	5.9
Haematopoietic and lymphoid	OPM2	5.9
Haematopoietic and lymphoid	P12ICHIKAWA	6.1
Haematopoietic and lymphoid	P31FUJ	5.2
Haematopoietic and lymphoid	P3HR1	6
Haematopoietic and lymphoid	PCM6	5.9
Haematopoietic and lymphoid	PEER	6.7
Haematopoietic and lymphoid	PF382	5.6
Haematopoietic and lymphoid	PFEIFFER	5.6
Haematopoietic and lymphoid	PL21	5.7
Haematopoietic and lymphoid	RAJI	5.8
Haematopoietic and lymphoid	RCHACV	5.8
Haematopoietic and lymphoid	REC1	6.2
Haematopoietic and lymphoid	REH	6.3
Haematopoietic and lymphoid	RI1	6.1
Haematopoietic and lymphoid	RL	5.7
Haematopoietic and lymphoid	RPMI8226	5.6
Haematopoietic and lymphoid	RPMI8402	5.8
Haematopoietic and lymphoid	RS411	5.9
Haematopoietic and lymphoid	SEM	5.8
Haematopoietic and lymphoid	SET2	6
Haematopoietic and lymphoid	SIGM5	6.2
Haematopoietic and lymphoid	SKM1	5.8
Haematopoietic and lymphoid	SKMM2	6
Haematopoietic and lymphoid	SR786	5.2
Haematopoietic and lymphoid	ST486	6.5
Haematopoietic and lymphoid	SUDHL10	5.7
Haematopoietic and lymphoid	SUDHL1	5.7
Haematopoietic and lymphoid	SUDHL4	5.9
Haematopoietic and lymphoid	SUDHL5	6.4
Haematopoietic and lymphoid	SUDHL6	6.1
Haematopoietic and lymphoid	SUDHL8	5.7
Haematopoietic and lymphoid	SUPB15	6.3
Haematopoietic and lymphoid	SUPHD1	5.6
Haematopoietic and lymphoid	SUPM2	4.8
Haematopoietic and lymphoid	SUPT11	6.5
Haematopoietic and lymphoid	SUPT1	5.9
Haematopoietic and lymphoid	TALL1	6.5
Haematopoietic and lymphoid	TF1	6
Haematopoietic and lymphoid	THP1	5.5
Haematopoietic and lymphoid	TO175T	5.7
Haematopoietic and lymphoid	TOLEDO	5.6
Haematopoietic and lymphoid	U266B1	6.3
Haematopoietic and lymphoid	U937	5.7
Haematopoietic and lymphoid	UT7	6
Haematopoietic and lymphoid	WSUDLCL2	5.2
Kidney	769P	5.6
Kidney	786O	5.5
Kidney	A498	5.5
Kidney	A704	5.5
Kidney	ACHN	5.7
Kidney	BFTC909	4.9
Kidney	CAKI1	5.8
Kidney	CAKI2	5.6
Kidney	CAL54	5.6
Kidney	KMRC1	5.2
Kidney	KMRC20	5.4
Kidney	KMRC2	5.8
Kidney	KMRC3	5.4
Kidney	OSRC2	5.5
Kidney	RCC10RGB	5.7
Kidney	SNU1272	5.6
Kidney	SNU349	5.7
Kidney	TUHR10TKB	6
Kidney	TUHR14TKB	5.6
Kidney	TUHR4TKB	5.5
Kidney	VMRCRCW	5.5
Kidney	VMRCRCZ	5.8
Large intestine	C2BBE1	5.5
Large intestine	CCK81	6.1
Large intestine	CL11	5.5
Large intestine	CL14	5.7
Large intestine	CL34	5.6
Large intestine	CL40	5.4
Large intestine	COLO205	6
Large intestine	COLO320	5.8
Large intestine	COLO678	5.4
Large intestine	CW2	5.6
Large intestine	DLD1	5.4
Large intestine	GP2D	5.7
Large intestine	HCC56	6
Large intestine	HCT116	5.9
Large intestine	HCT15	5.5
Large intestine	HS675T	4.9
Large intestine	HS698T	5.8
Large intestine	HT115	6.1
Large intestine	HT29	5.2
Large intestine	HT55	5.9
Large intestine	KM12	4.9
Large intestine	LOVO	5.6
Large intestine	LS1034	5.6
Large intestine	LS123	6.1
Large intestine	LS180	5.6
Large intestine	LS411N	5.5
Large intestine	LS513	5.3
Large intestine	MDST8	5.2
Large intestine	NCIH508	5.3
Large intestine	NCIH716	6
Large intestine	NCIH747	5.5
Large intestine	OUMS23	5.6
Large intestine	RCM1	5.7
Large intestine	RKO	5.7
Large intestine	SKCO1	5.1
Large intestine	SNU1040	5.5
Large intestine	SNU1197	5.5
Large intestine	SNU175	5.5
Large intestine	SNU283	5.5
Large intestine	SNU407	5.2
Large intestine	SNU503	5.6
Large intestine	SNU61	5.8
Large intestine	SNU81	5.6
Large intestine	SNUC1	5.8
Large intestine	SNUC2A	5.4
Large intestine	SNUC4	5.7
Large intestine	SNUC5	5.9
Large intestine	SW1116	6.1
Large intestine	SW1417	5.5
Large intestine	SW1463	5.3
Large intestine	SW403	5.8
Large intestine	SW480	5.2
Large intestine	SW48	5.4
Large intestine	SW620	5.6
Large intestine	SW837	5.3
Large intestine	SW948	5.3
Large intestine	T84	6
Liver	ALEXANDERCELLS	4.7
Liver	C3A	5.9
Liver	HEP3B217	5.9
Liver	HEPG2	5.9
Liver	HLE	5.1
Liver	HLF	5.7
Liver	HUH1	5.3
Liver	HUH6	5.9
Liver	HUH7	5.7
Liver	JHH1	5.7
Liver	JHH2	5.2
Liver	JHH4	5.6
Liver	JHH5	5.4
Liver	JHH6	5.1
Liver	JHH7	5.1
Liver	LI7	5.5
Liver	PLCPRF5	5.6
Liver	SKHEP1	5.1
Liver	SNU182	5.7
Liver	SNU387	5.4
Liver	SNU398	5.5
Liver	SNU423	5.4
Liver	SNU449	5.5
Liver	SNU475	5.2
Liver	SNU761	5.6
Liver	SNU878	5.1
Liver	SNU886	6
Lung	A549	5.4
Lung	ABC1	5.6
Lung	BEN	5.8
Lung	CAL12T	5.6
Lung	CALU1	5.2
Lung	CALU3	5.1
Lung	CALU6	5.3
Lung	CHAGOK1	5.2
Lung	COLO668	5.8
Lung	COLO699	5.7
Lung	CORL105	6.1
Lung	CORL23	5.5
Lung	CORL24	4.9
Lung	CORL279	5.8
Lung	CORL311	5.6
Lung	CORL47	5.4
Lung	CORL51	5.3
Lung	CORL88	5.8
Lung	CORL95	5.4
Lung	CPCN	5.9
Lung	DMS114	5.7
Lung	DMS153	5.6
Lung	DMS273	5.7
Lung	DMS454	5.4
Lung	DMS53	5.7
Lung	DMS79	5.3
Lung	DV90	5.8
Lung	EBC1	6
Lung	EPLC272H	5.1
Lung	HARA	5.7
Lung	HCC1171	5.9
Lung	HCC1195	5.5
Lung	HCC15	5.1
Lung	HCC2279	5.8
Lung	HCC2935	5.5
Lung	HCC33	6.1
Lung	HCC366	5.7
Lung	HCC4006	5.6
Lung	HCC44	5.8
Lung	HCC78	5.5
Lung	HCC827	5.4
Lung	HCC95	5
Lung	HLC1	5.9
Lung	HLFA	5.1
Lung	HS229T	5.2
Lung	HS618T	5.1
Lung	IALM	5.7
Lung	KNS62	5.4
Lung	LC1F	6
Lung	LC1SQSF	5.8
Lung	LCLC103H	5.3
Lung	LCLC97TM1	5.6
Lung	LK2	5.4
Lung	LOUNH91	5.6
Lung	LU65	5.6
Lung	LU99	5.6
Lung	LUDLU1	5.5
Lung	LXF289	5.4
Lung	MORCPR	5.8
Lung	NCIH1048	5.6
Lung	NCIH1092	5.6
Lung	NCIH1105	5.7
Lung	NCIH1155	5.2
Lung	NCIH1184	5.3
Lung	NCIH1299	5.7
Lung	NCIH1339	5.5
Lung	NCIH1341	5.3
Lung	NCIH1355	5.2
Lung	NCIH1373	6
Lung	NCIH1385	5.7
Lung	NCIH1395	5.5
Lung	NCIH1435	5.6
Lung	NCIH1436	5.6
Lung	NCIH1437	5.9
Lung	NCIH146	5.5
Lung	NCIH1563	5.5
Lung	NCIH1568	5.2
Lung	NCIH1573	6
Lung	NCIH1581	5.7
Lung	NCIH1618	5.5
Lung	NCIH1623	5.5
Lung	NCIH1648	5.6
Lung	NCIH1650	5.3
Lung	NCIH1651	5.4
Lung	NCIH1666	5.8
Lung	NCIH1693	5.7
Lung	NCIH1694	5.4
Lung	NCIH1703	5.4
Lung	NCIH1734	5.2
Lung	NCIH1755	5.7
Lung	NCIH1781	5.5
Lung	NCIH1792	5.2
Lung	NCIH1793	5.2
Lung	NCIH1836	5.7
Lung	NCIH1838	5.8
Lung	NCIH1869	5.6
Lung	NCIH1876	6.1
Lung	NCIH1915	5.6
Lung	NCIH1930	5.7
Lung	NCIH1944	5
Lung	NCIH1963	5.8
Lung	NCIH196	5.2
Lung	NCIH1975	5.4
Lung	NCIH2009	5.4
Lung	NCIH2023	5.8
Lung	NCIH2029	5.6
Lung	NCIH2030	5.5
Lung	NCIH2066	5.3
Lung	NCIH2081	5.3
Lung	NCIH2085	5.6
Lung	NCIH2087	5.4
Lung	NCIH209	5.3
Lung	NCIH2106	6.3
Lung	NCIH2110	4.9
Lung	NCIH211	5.4
Lung	NCIH2122	5.2
Lung	NCIH2126	5.1
Lung	NCIH2141	5.6
Lung	NCIH2170	5.8
Lung	NCIH2171	5.5
Lung	NCIH2172	5.4
Lung	NCIH2196	5.3
Lung	NCIH2227	6.2
Lung	NCIH2228	5.1
Lung	NCIH226	5.6
Lung	NCIH2286	6
Lung	NCIH2291	5.7
Lung	NCIH2342	5.8
Lung	NCIH2347	4.9
Lung	NCIH23	6.2
Lung	NCIH2405	5.7
Lung	NCIH2444	5.2
Lung	NCIH292	5.8
Lung	NCIH322	5.2
Lung	NCIH3255	5.8
Lung	NCIH358	5.4
Lung	NCIH441	5.6
Lung	NCIH446	5
Lung	NCIH460	5.6
Lung	NCIH510	6
Lung	NCIH520	5.8
Lung	NCIH522	5.4
Lung	NCIH524	5.7
Lung	NCIH526	5.2
Lung	NCIH596	5.4
Lung	NCIH647	5
Lung	NCIH650	5.4
Lung	NCIH661	5.3
Lung	NCIH69	6
Lung	NCIH727	5.4
Lung	NCIH810	6.5
Lung	NCIH82	5.7
Lung	NCIH838	5.7
Lung	NCIH841	5.5
Lung	NCIH854	5.6
Lung	NCIH889	5.5
Lung	PC14	6
Lung	RERFLCAD1	5.5
Lung	RERFLCAD2	5.9
Lung	RERFLCAI	5.4
Lung	RERFLCKJ	5
Lung	RERFLCMS	5.1
Lung	RERFLCSQ1	5.4
Lung	SBC5	5.2
Lung	SCLC21H	5.4
Lung	SHP77	5.1
Lung	SKLU1	5.1
Lung	SKMES1	5.4
Lung	SQ1	5.8
Lung	SW1271	5.5
Lung	SW1573	5.6
Lung	SW900	5.2
Lung	VMRCLCD	6.4
Lung	VMRCLCP	5.8
Oesophagus	COLO680N	5.6
Oesophagus	ECGI10	5.6
Oesophagus	KYSE140	5.8
Oesophagus	KYSE150	5.4
Oesophagus	KYSE180	6.3
Oesophagus	KYSE270	6
Oesophagus	KYSE30	5.6
Oesophagus	KYSE410	5.8
Oesophagus	KYSE450	5.8
Oesophagus	KYSE510	5.5
Oesophagus	KYSE520	5.8
Oesophagus	KYSE70	5.1
Oesophagus	OE19	5
Oesophagus	OE33	5.4
Oesophagus	TE10	6
Oesophagus	TE11	5.9
Oesophagus	TE14	5.6
Oesophagus	TE15	5.4
Oesophagus	TE1	5.4
Oesophagus	TE4	6.1
Oesophagus	TE5	5.9
Oesophagus	TE6	5.6
Oesophagus	TE8	5.7
Oesophagus	TE9	5.6
Oesophagus	TT	5.7
Ovary	59M	6
Ovary	A2780	6.1
Ovary	CAOV3	5.6
Ovary	CAOV4	5.8
Ovary	COLO704	5.3
Ovary	COV318	5.7
Ovary	COV362	5.1
Ovary	COV434	5.7
Ovary	COV504	5.6
Ovary	COV644	5.3
Ovary	EFO21	5.4
Ovary	EFO27	5
Ovary	ES2	5.2
Ovary	FUOV1	5.6
Ovary	HEYA8	5
Ovary	HS571T	4.9
Ovary	IGROV1	5.2
Ovary	JHOC5	5.6
Ovary	JHOM1	5.3
Ovary	JHOM2B	5.5
Ovary	JHOS2	5.3
Ovary	JHOS4	5.6
Ovary	KURAMOCHI	6.5
Ovary	MCAS	5.4
Ovary	NIHOVCAR3	5.3
Ovary	OAW28	5.7
Ovary	OAW42	5.8
Ovary	OC314	5.5
Ovary	OC316	5.7
Ovary	ONCODG1	5.4
Ovary	OV56	5.8
Ovary	OV7	5.6
Ovary	OV90	5.8
Ovary	OVCAR4	5.6
Ovary	OVCAR8	5.3
Ovary	OVISE	5.4
Ovary	OVK18	6.1
Ovary	OVKATE	5.3
Ovary	OVMANA	5.6
Ovary	OVSAHO	4.7
Ovary	OVTOKO	5.2
Ovary	RMGI	6.2
Ovary	RMUGS	5.5
Ovary	SKOV3	5
Ovary	SNU119	5.3
Ovary	SNU840	5.6
Ovary	SNU8	5.5
Ovary	TOV112D	5.4
Ovary	TOV21G	4.9
Ovary	TYKNU	5.2
Pancreas	ASPC1	5.4
Pancreas	BXPC3	5.1
Pancreas	CAPAN1	5.4
Pancreas	CAPAN2	5.1
Pancreas	CFPAC1	5.2
Pancreas	DANG	5.4
Pancreas	HPAC	5.8
Pancreas	HPAFII	5.4
Pancreas	HS766T	5.4
Pancreas	HUPT3	5.5
Pancreas	HUPT4	5.5
Pancreas	KCIMOH1	4.9
Pancreas	KLM1	6.5
Pancreas	KP2	5.2
Pancreas	KP3	5.4
Pancreas	KP4	5.6
Pancreas	L33	5.8
Pancreas	MIAPACA2	6.5
Pancreas	PANC0203	6
Pancreas	PANC0213	5.5
Pancreas	PANC0327	5.6
Pancreas	PANC0403	4.9
Pancreas	PANC0504	5.4
Pancreas	PANC0813	5.4
Pancreas	PANC1005	5.8
Pancreas	PANC1	5.8
Pancreas	PATU8902	5.8
Pancreas	PATU8988S	5.9
Pancreas	PATU8988T	5.4
Pancreas	PK1	5.2
Pancreas	PK45H	5.2
Pancreas	PK59	5.2
Pancreas	PL45	5.7
Pancreas	PSN1	5.3
Pancreas	QGP1	5.4
Pancreas	SNU213	5.3
Pancreas	SNU324	5.8
Pancreas	SNU410	5.7
Pancreas	SU8686	5.4
Pancreas	SUIT2	5.3
Pancreas	SW1990	5.5
Pancreas	T3M4	5.6
Pancreas	TCCPAN2	5.3
Pancreas	YAPC	5.4
Pleura	ACCMESO1	5
Pleura	DM3	5.3
Pleura	ISTMES1	5.5
Pleura	ISTMES2	6.2
Pleura	JL1	5.5
Pleura	MPP89	5
Pleura	MSTO211H	5.1
Pleura	NCIH2052	4.9
Pleura	NCIH2452	5.9
Pleura	NCIH28	5.7
Prostate	22RV1	5.2
Prostate	DU145	5.4
Prostate	LNCAPCLONEFGC	5.2
Prostate	MDAPCA2B	5.2
Prostate	NCIH660	5.9
Prostate	PC3	5.7
Prostate	VCAP	5.3
Salivary gland	A253	5.4
Salivary gland	YD15	6
Skin	A101D	5.4
Skin	A2058	5.8
Skin	A375	5.5
Skin	C32	5.3
Skin	CHL1	5.3
Skin	CJM	5.6
Skin	COLO679	5.3
Skin	COLO741	5.2
Skin	COLO783	5.3
Skin	COLO792	5.5
Skin	COLO800	5.4
Skin	COLO818	4.7
Skin	COLO829	5.4
Skin	COLO849	5.6
Skin	G361	5.3
Skin	GRM	6.3
Skin	HMCB	5.8
Skin	HS294T	5.1
Skin	HS600T	5.9
Skin	HS688AT	5.3
Skin	HS695T	5.3
Skin	HS839T	5.5
Skin	HS852T	5.2
Skin	HS895T	5
Skin	HS934T	4.9
Skin	HS936T	5.5
Skin	HS939T	5.5
Skin	HS940T	5.3
Skin	HS944T	4.8
Skin	HT144	5.9
Skin	IGR1	5.4
Skin	IGR37	5.8
Skin	IGR39	5.5
Skin	IPC298	5.5
Skin	K029AX	5.1
Skin	LOXIMVI	5.4
Skin	MALME3M	5.3
Skin	MDAMB435S	5.2
Skin	MELHO	5.1
Skin	MELJUSO	5.2
Skin	MEWO	5.3
Skin	RPMI7951	5.1
Skin	RVH421	5.1
Skin	SH4	5.3
Skin	SKMEL1	5.5
Skin	SKMEL24	5.3
Skin	SKMEL28	5.6
Skin	SKMEL2	5.2
Skin	SKMEL30	5.4
Skin	SKMEL31	5.6
Skin	SKMEL3	5.1
Skin	SKMEL5	5.3
Skin	UACC257	5.2
Skin	UACC62	5.2
Skin	WM115	5.1
Skin	WM1799	5.1
Skin	WM2664	5.1
Skin	WM793	5.2
Skin	WM88	5.4
Skin	WM983B	5.2
Small intestine	HUTU80	5.8
Soft tissue	A204	5.4
Soft tissue	G401	5.8
Soft tissue	G402	5.7
Soft tissue	GCT	5.4
Soft tissue	HS729	5.3
Soft tissue	HT1080	5.6
Soft tissue	KYM1	5.5
Soft tissue	MESSA	5.6
Soft tissue	RD	5.3
Soft tissue	RH30	6.3
Soft tissue	RH41	5.9
Soft tissue	RKN	5.3
Soft tissue	S117	5.3
Soft tissue	SJRH30	5.7
Soft tissue	SKLMS1	5.4
Soft tissue	SKUT1	5.7
Soft tissue	TE125T	5.2
Soft tissue	TE159T	6
Soft tissue	TE441T	5.7
Soft tissue	TE617T	6
Stomach	2313287	5.4
Stomach	AGS	6
Stomach	AZ521	6
Stomach	ECC10	5.7
Stomach	ECC12	6
Stomach	FU97	5.3
Stomach	GCIY	5.7
Stomach	GSS	5.8
Stomach	GSU	5.9
Stomach	HGC27	6.4
Stomach	HS746T	5.6
Stomach	HUG1N	6
Stomach	IM95	5.5
Stomach	KATOIII	5.5
Stomach	KE39	5.4
Stomach	LMSU	5.4
Stomach	MKN1	5.7
Stomach	MKN45	5.6
Stomach	MKN74	5.7
Stomach	MKN7	5.6
Stomach	NCCSTCK140	6.3
Stomach	NCIN87	5.7
Stomach	NUGC2	5.8
Stomach	NUGC3	5.2
Stomach	NUGC4	5.7
Stomach	OCUM1	5.6
Stomach	RERFGC1B	5.4
Stomach	SH10TC	5.7
Stomach	SNU16	5.4
Stomach	SNU1	6.2
Stomach	SNU216	5.3
Stomach	SNU520	5.9
Stomach	SNU5	5.5
Stomach	SNU601	6
Stomach	SNU620	5.5
Stomach	SNU668	6.6
Stomach	SNU719	6.1
Stomach	TGBC11TKB	5.7
Thyroid	8305C	5.5
Thyroid	8505C	5.4
Thyroid	BCPAP	5.7
Thyroid	BHT101	5.5
Thyroid	CAL62	5.4
Thyroid	CGTHW1	5.4
Thyroid	FTC133	5.1
Thyroid	FTC238	5.2
Thyroid	ML1	5.6
Thyroid	SW579	5.4
Thyroid	TT2609C02	5.6
Thyroid	TT	5.3
Upper aerodigestive tract	BHY	5.6
Upper aerodigestive tract	BICR16	5.5
Upper aerodigestive tract	BICR18	5.4
Upper aerodigestive tract	BICR22	6
Upper aerodigestive tract	BICR31	5.6
Upper aerodigestive tract	BICR56	6.1
Upper aerodigestive tract	BICR6	5.5
Upper aerodigestive tract	CAL27	4.7
Upper aerodigestive tract	CAL33	6
Upper aerodigestive tract	DETROIT562	5.3
Upper aerodigestive tract	FADU	5.8
Upper aerodigestive tract	HS840T	5.1
Upper aerodigestive tract	HSC2	5.8
Upper aerodigestive tract	HSC3	5.1
Upper aerodigestive tract	HSC4	5.5
Upper aerodigestive tract	PECAPJ15	5.4
Upper aerodigestive tract	PECAPJ34CLONEC12	5.1
Upper aerodigestive tract	PECAPJ41CLONED2	6
Upper aerodigestive tract	PECAPJ49	5.6
Upper aerodigestive tract	SCC15	5.2
Upper aerodigestive tract	SCC25	5.4
Upper aerodigestive tract	SCC4	5.8
Upper aerodigestive tract	SCC9	5.5
Upper aerodigestive tract	SNU1076	5.3
Upper aerodigestive tract	SNU1214	5.6
Upper aerodigestive tract	SNU46	5.2
Upper aerodigestive tract	SNU899	5.5
Upper aerodigestive tract	YD10B	5.8
Upper aerodigestive tract	YD38	5.1
Upper aerodigestive tract	YD8	5.6
Urinary tract	5637	5.8
Urinary tract	639V	5.8
Urinary tract	647V	5.4
Urinary tract	BC3C	5.7
Urinary tract	BFTC905	5.6
Urinary tract	CAL29	5.3
Urinary tract	HS172T	5.2
Urinary tract	HT1197	5.3
Urinary tract	HT1376	6
Urinary tract	J82	5.6
Urinary tract	JMSU1	6.2
Urinary tract	KMBC2	5.4
Urinary tract	KU1919	5.6
Urinary tract	RT11284	5.5
Urinary tract	RT112	5.2
Urinary tract	RT4	5.3
Urinary tract	SCABER	6.2
Urinary tract	SW1710	5.5
Urinary tract	SW780	5.8
Urinary tract	T24	5.3
Urinary tract	TCCSUP	5.8
Urinary tract	UMUC1	5.6
Urinary tract	UMUC3	5.7
Urinary tract	VMCUB1	5.3

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	8.6
Adrenal gland	7.2
Appendix	9.5
Bone marrow	12
Breast	5
Cerebral cortex	10
Cervix, uterine	8.6
Colon	5.4
Duodenum	6.2
Endometrium	13
Epididymis	3
Esophagus	7.4
Fallopian tube	12.7
Gallbladder	8.2
Heart muscle	3.9
Kidney	4.4
Liver	2.1
Lung	9.2
Lymph node	10.1
Ovary	12
Pancreas	1.8
Parathyroid gland	21.7
Placenta	8
Prostate	7.7
Rectum	6.1
Salivary gland	3.1
Seminal vesicle	8.4
Skeletal muscle	3.6
Skin	8.8
Small intestine	6.9
Smooth muscle	13.7
Spleen	10.9
Stomach	5.3
Testis	24.7
Thyroid gland	12
Tonsil	7.4
Urinary bladder	6

> Text Mining based Expression [ TOP ]
There is no record.

Summary
Symbol	SETD1A
Name	SET domain containing 1A
Aliases	KIAA0339; Set1; KMT2F; Set1A; SET domain-containing protein 1A; hSET1A; lysine N-methyltransferase 2F; set1/ ......
Location	16p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.526	3.48e-30	23.5	54.5	22	Neutral
BRCA	Breast invasive carcinoma	1075	0.611	7.29e-111	8.4	40.7	51	Gain
CESC	Cervical and endocervical cancers	292	0.539	2.26e-23	12.3	73.6	14	Neutral
COAD	Colon adenocarcinoma	449	0.266	1.01e-08	4.7	67.5	27.8	Neutral
ESCA	Esophageal carcinoma	183	0.515	8.35e-14	24.6	50.3	25.1	Neutral
GBM	Glioblastoma multiforme	147	0.274	0.000797	15.6	78.9	5.4	Neutral
HNSC	Head and Neck squamous cell carcinoma	514	0.405	1.11e-21	10.9	67.3	21.8	Neutral
KIRC	Kidney renal clear cell carcinoma	525	0.187	1.65e-05	2.3	77.1	20.6	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	0.517	4.57e-21	1	45.5	53.5	Gain
LAML	Acute Myeloid Leukemia	166	0.197	0.011	2.4	97.6	0	Neutral
LGG	Brain Lower Grade Glioma	513	0.222	3.99e-07	3.5	93.6	2.9	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.531	6.36e-28	24.5	64.3	11.3	Neutral
LUAD	Lung adenocarcinoma	512	0.364	1.82e-17	15.4	52	32.6	Neutral
LUSC	Lung squamous cell carcinoma	498	0.337	1.11e-14	25.7	50.4	23.9	Neutral
OV	Ovarian serous cystadenocarcinoma	300	0.508	3.99e-21	36.7	45.3	18	Loss
PAAD	Pancreatic adenocarcinoma	177	0.037	0.63	4.5	81.9	13.6	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	0.382	5.14e-07	4.9	91.4	3.7	Neutral
PRAD	Prostate adenocarcinoma	491	0.338	1.35e-14	6.7	86.8	6.5	Neutral
READ	Rectum adenocarcinoma	164	0.421	1.95e-08	4.9	67.1	28	Neutral
SARC	Sarcoma	255	0.602	1.59e-26	23.1	56.5	20.4	Neutral
SKCM	Skin Cutaneous Melanoma	367	0.393	5.24e-15	16.3	66.2	17.4	Neutral
STAD	Stomach adenocarcinoma	413	0.478	5.65e-25	17.7	64.2	18.2	Neutral
TGCT	Testicular Germ Cell Tumors	150	0.141	0.0841	28	60	12	Neutral
THCA	Thyroid carcinoma	497	0.219	8.29e-07	0.2	97.2	2.6	Neutral
THYM	Thymoma	119	0.197	0.0321	2.5	94.1	3.4	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.55	9.99e-44	10.6	77.1	12.3	Neutral

Summary
Symbol	SETD1A
Name	SET domain containing 1A
Aliases	KIAA0339; Set1; KMT2F; Set1A; SET domain-containing protein 1A; hSET1A; lysine N-methyltransferase 2F; set1/ ......
Location	16p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

[ TOP ]

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.392	0	17	408	-0.158	1.27e-13	NS/NA
BRCA	Breast invasive carcinoma	-0.179	1.23e-07	83	785	0.001	0.833	NS/NA
CESC	Cervical and endocervical cancers	-0.226	6.34e-05	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.232	3.23e-05	19	297	-0.055	0.0501	NS/NA
ESCA	Esophageal carcinoma	-0.236	0.000966	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.311	0.0119	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.179	2.84e-05	20	522	0.003	7.47e-06	NS/NA
KIRC	Kidney renal clear cell carcinoma	-0.145	0.007	24	319	-0.039	6.63e-20	NS/NA
KIRP	Kidney renal papillary cell carcinoma	-0.275	1.6e-06	23	275	-0.001	0.0151	NS/NA
LAML	Acute Myeloid Leukemia	-0.065	0.401	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	-0.064	0.138	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.232	2.02e-06	41	373	-0.188	3.29e-27	NS/NA
LUAD	Lung adenocarcinoma	-0.286	2.45e-10	21	456	-0.111	1.13e-08	NS/NA
LUSC	Lung squamous cell carcinoma	-0.382	1.51e-14	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	-0.833	0.00827	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.218	0.00303	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.118	0.107	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.117	0.00667	35	498	0.003	0.000254	NS/NA
READ	Rectum adenocarcinoma	-0.147	0.143	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.346	9.86e-09	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.192	2.72e-05	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.186	0.000313	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.755	0	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.179	2.15e-05	50	509	-0.077	0.0214	NS/NA
THYM	Thymoma	-0.179	0.0484	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.094	0.0419	34	431	-0.024	9.85e-12	NS/NA

Summary
Symbol	SETD1A
Name	SET domain containing 1A
Aliases	KIAA0339; Set1; KMT2F; Set1A; SET domain-containing protein 1A; hSET1A; lysine N-methyltransferase 2F; set1/ ......
Location	16p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Level	Level Name
Adrenal gland	2	Medium
Appendix	2	Medium
Bone marrow	3	High
Breast	2	Medium
Bronchus	3	High
Caudate	2	Medium
Cerebellum	2	Medium
Cerebral cortex	2	Medium
Cervix, uterine	3	High
Colon	2	Medium
Duodenum	2	Medium
Endometrium	2	Medium
Epididymis	2	Medium
Esophagus	2	Medium
Fallopian tube	2	Medium
Gallbladder	2	Medium
Heart muscle	2	Medium
Hippocampus	2	Medium
Kidney	2	Medium
Liver	1	Low
Lung	2	Medium
Lymph node	2	Medium
Nasopharynx	3	High
Oral mucosa	2	Medium
Ovary	1	Low
Pancreas	2	Medium
Parathyroid gland	1	Low
Placenta	2	Medium
Prostate	1	Low
Rectum	2	Medium
Salivary gland	2	Medium
Seminal vesicle	2	Medium
Skeletal muscle	2	Medium
Skin	2	Medium
Small intestine	2	Medium
Smooth muscle	2	Medium
Soft tissue	2	Medium
Spleen	2	Medium
Stomach	2	Medium
Testis	3	High
Thyroid gland	2	Medium
Tonsil	2	Medium
Urinary bladder	2	Medium
Vagina	2	Medium

Summary
Symbol	SETD1A
Name	SET domain containing 1A
Aliases	KIAA0339; Set1; KMT2F; Set1A; SET domain-containing protein 1A; hSET1A; lysine N-methyltransferase 2F; set1/ ......
Location	16p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.939	NS	24476821
BRCA	Breast invasive carcinoma	521	0.0544	NS	23000897
COAD	Colon adenocarcinoma	149	0.000788	Significant	22810696
GBM	Glioblastoma multiforme	157	0.0113	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	0.00427	Significant	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.288	NS	26536169
LGG	Brain Lower Grade Glioma	513	1.8e-10	Significant	26824661
LUAD	Lung adenocarcinoma	230	0.239	NS	25079552
LUSC	Lung squamous cell carcinoma	178	0.00486	Significant	22960745
OV	Ovarian serous cystadenocarcinoma	287	0.000781	Significant	21720365
PRAD	Prostate adenocarcinoma	333	0.000566	Significant	26544944
READ	Rectum adenocarcinoma	67	0.324	NS	22810696
SKCM	Skin Cutaneous Melanoma	315	0.0572	NS	26091043
STAD	Stomach adenocarcinoma	277	0.0714	NS	25079317
THCA	Thyroid carcinoma	391	0.055	NS	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	5.66e-07	Significant	23636398

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	1.007	0.976	NS
BRCA	Breast invasive carcinoma	1079	1.169	0.513	NS
CESC	Cervical and endocervical cancers	291	0.699	0.323	NS
COAD	Colon adenocarcinoma	439	1.243	0.474	NS
ESCA	Esophageal carcinoma	184	0.37	0.00439	Longer
GBM	Glioblastoma multiforme	158	0.917	0.715	NS
HNSC	Head and Neck squamous cell carcinoma	518	0.751	0.145	NS
KIRC	Kidney renal clear cell carcinoma	531	1.844	0.00489	Shorter
KIRP	Kidney renal papillary cell carcinoma	287	1.129	0.775	NS
LAML	Acute Myeloid Leukemia	149	1.401	0.258	NS
LGG	Brain Lower Grade Glioma	511	0.698	0.144	NS
LIHC	Liver hepatocellular carcinoma	365	1.02	0.937	NS
LUAD	Lung adenocarcinoma	502	1.104	0.63	NS
LUSC	Lung squamous cell carcinoma	494	0.859	0.462	NS
OV	Ovarian serous cystadenocarcinoma	303	0.996	0.985	NS
PAAD	Pancreatic adenocarcinoma	177	0.701	0.218	NS
PCPG	Pheochromocytoma and Paraganglioma	179	0.341	0.378	NS
PRAD	Prostate adenocarcinoma	497	2.612	0.39	NS
READ	Rectum adenocarcinoma	159	1.482	0.477	NS
SARC	Sarcoma	259	0.943	0.83	NS
SKCM	Skin Cutaneous Melanoma	459	1.652	0.00977	Shorter
STAD	Stomach adenocarcinoma	388	0.841	0.433	NS
TGCT	Testicular Germ Cell Tumors	134	0.705	0.779	NS
THCA	Thyroid carcinoma	500	1.134	0.835	NS
THYM	Thymoma	119	0.146	0.0416	Longer
UCEC	Uterine Corpus Endometrial Carcinoma	543	1.125	0.702	NS

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	-0.108	0.0289	Lower
BRCA	Breast invasive carcinoma	1071	-0.036	0.242	NS
CESC	Cervical and endocervical cancers	167	0.038	0.629	NS
COAD	Colon adenocarcinoma	445	0.098	0.0379	Higher
ESCA	Esophageal carcinoma	162	-0.197	0.0118	Lower
HNSC	Head and Neck squamous cell carcinoma	448	0.088	0.0632	NS
KIRC	Kidney renal clear cell carcinoma	531	0.072	0.0995	NS
KIRP	Kidney renal papillary cell carcinoma	260	0.097	0.12	NS
LIHC	Liver hepatocellular carcinoma	347	0.109	0.0423	Higher
LUAD	Lung adenocarcinoma	507	0.009	0.837	NS
LUSC	Lung squamous cell carcinoma	497	0.049	0.275	NS
OV	Ovarian serous cystadenocarcinoma	302	-0.145	0.0115	Lower
PAAD	Pancreatic adenocarcinoma	176	-0.11	0.146	NS
READ	Rectum adenocarcinoma	156	0.019	0.812	NS
SKCM	Skin Cutaneous Melanoma	410	-0.108	0.0294	Lower
STAD	Stomach adenocarcinoma	392	-0.031	0.545	NS
TGCT	Testicular Germ Cell Tumors	81	-0.331	0.00252	Lower
THCA	Thyroid carcinoma	499	0.091	0.0417	Higher
UCEC	Uterine Corpus Endometrial Carcinoma	501	0.082	0.0675	NS

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	0.001	0.985	NS
HNSC	Head and Neck squamous cell carcinoma	498	0.019	0.68	NS
KIRC	Kidney renal clear cell carcinoma	525	0.092	0.0358	Higher
LGG	Brain Lower Grade Glioma	514	0.028	0.532	NS
LIHC	Liver hepatocellular carcinoma	366	-0.002	0.97	NS
OV	Ovarian serous cystadenocarcinoma	296	0.059	0.312	NS
PAAD	Pancreatic adenocarcinoma	176	0.07	0.357	NS
STAD	Stomach adenocarcinoma	406	-0.039	0.437	NS
UCEC	Uterine Corpus Endometrial Carcinoma	534	0.173	5.78e-05	Higher

Summary
Symbol	SETD1A
Name	SET domain containing 1A
Aliases	KIAA0339; Set1; KMT2F; Set1A; SET domain-containing protein 1A; hSET1A; lysine N-methyltransferase 2F; set1/ ......
Location	16p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	SETD1A
Name	SET domain containing 1A
Aliases	KIAA0339; Set1; KMT2F; Set1A; SET domain-containing protein 1A; hSET1A; lysine N-methyltransferase 2F; set1/ ......
Location	16p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for SETD1A.

Summary
Symbol	SETD1A
Name	SET domain containing 1A
Aliases	KIAA0339; Set1; KMT2F; Set1A; SET domain-containing protein 1A; hSET1A; lysine N-methyltransferase 2F; set1/ ......
Location	16p11.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining [ TOP ]
There is no record for SETD1A.