CR2Cancer

Summary
Symbol	TDRD5
Name	tudor domain containing 5
Aliases	FLJ34823; TUDOR3; Tudor domain-containing protein 5
Location	1q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

[ TOP ]

Domain

PF12872 OST-HTH/LOTUS domain
PF00567 Tudor domain

Function

Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity).

Classification

Class	Modification	Substrate	Product	PubMed
#	#	#	#	#

> Gene Ontology [ TOP ]
Biological Process	GO:0000578 embryonic axis specification GO:0003002 regionalization GO:0006304 DNA modification GO:0006305 DNA alkylation GO:0006306 DNA methylation GO:0007028 cytoplasm organization GO:0007281 germ cell development GO:0007283 spermatogenesis GO:0007286 spermatid development GO:0007292 female gamete generation GO:0007308 oocyte construction GO:0007309 oocyte axis specification GO:0007314 oocyte anterior/posterior axis specification GO:0007315 pole plasm assembly GO:0007350 blastoderm segmentation GO:0007351 tripartite regional subdivision GO:0007389 pattern specification process GO:0008358 maternal determination of anterior/posterior axis, embryo GO:0008595 anterior/posterior axis specification, embryo GO:0009798 axis specification GO:0009880 embryonic pattern specification GO:0009948 anterior/posterior axis specification GO:0009952 anterior/posterior pattern specification GO:0009994 oocyte differentiation GO:0021700 developmental maturation GO:0022412 cellular process involved in reproduction in multicellular organism GO:0030719 P granule organization GO:0032259 methylation GO:0035282 segmentation GO:0043046 DNA methylation involved in gamete generation GO:0043414 macromolecule methylation GO:0044728 DNA methylation or demethylation GO:0048232 male gamete generation GO:0048469 cell maturation GO:0048477 oogenesis GO:0048515 spermatid differentiation GO:0048599 oocyte development GO:0071826 ribonucleoprotein complex subunit organization
Molecular Function	-
Cellular Component	GO:0033391 chromatoid body GO:0035770 ribonucleoprotein granule GO:0036464 cytoplasmic ribonucleoprotein granule GO:0043186 P granule GO:0045495 pole plasm GO:0060293 germ plasm GO:0071546 pi-body

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	-

Summary
Symbol	TDRD5
Name	tudor domain containing 5
Aliases	FLJ34823; TUDOR3; Tudor domain-containing protein 5
Location	1q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM226478	c.1663G>A	p.E555K	Substitution - Missense	Skin
COSM2095541	c.1953G>C	p.L651F	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4956739	c.356G>T	p.R119L	Substitution - Missense	Liver
COSM677837	c.1665A>T	p.E555D	Substitution - Missense	Lung
COSM3705284	c.2343+9C>T	p.?	Unknown	Liver
COSM385009	c.1409G>A	p.S470N	Substitution - Missense	Lung
COSM1668244	c.1484C>T	p.S495L	Substitution - Missense	Large_intestine
COSM5630237	c.344C>T	p.P115L	Substitution - Missense	Oesophagus
COSM5378673	c.2687C>T	p.P896L	Substitution - Missense	Skin
COSM404394	c.1172C>G	p.P391R	Substitution - Missense	Lung
COSM3479301	c.1553G>A	p.R518Q	Substitution - Missense	Skin
COSM3724902	c.2174C>A	p.T725N	Substitution - Missense	Lung
COSM3479289	c.1027G>A	p.E343K	Substitution - Missense	Skin
COSM5965185	c.864G>A	p.Q288Q	Substitution - coding silent	Breast
COSM463498	c.1631G>A	p.R544Q	Substitution - Missense	Kidney
COSM3360521	c.124C>A	p.H42N	Substitution - Missense	Kidney
COSM3479348	c.2901G>A	p.R967R	Substitution - coding silent	Skin
COSM5705055	c.2516C>T	p.S839F	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1336716	c.1901delT	p.L636fs*16	Deletion - Frameshift	Large_intestine
COSM5427676	c.1630C>T	p.R544W	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1228829	c.542C>T	p.A181V	Substitution - Missense	Prostate
COSM677844	c.1021G>C	p.V341L	Substitution - Missense	Lung
COSM2095547	c.2128C>T	p.P710S	Substitution - Missense	Skin
COSM4940406	c.2238T>A	p.P746P	Substitution - coding silent	Liver
COSM5480950	c.1838A>G	p.K613R	Substitution - Missense	Large_intestine
COSM3976625	c.1293A>G	p.L431L	Substitution - coding silent	Lung
COSM3976621	c.915+10T>A	p.?	Unknown	Lung
COSM4732904	c.1570T>C	p.C524R	Substitution - Missense	Large_intestine
COSM4941895	c.1092A>T	p.L364L	Substitution - coding silent	Liver
COSM3418419	c.1552C>T	p.R518*	Substitution - Nonsense	Skin
COSM5723508	c.2092C>T	p.Q698*	Substitution - Nonsense	Skin
COSM900301	c.1593C>A	p.L531L	Substitution - coding silent	Endometrium
COSM1689314	c.1480G>A	p.D494N	Substitution - Missense	Skin
COSM3418417	c.136C>T	p.R46*	Substitution - Nonsense	Large_intestine
COSM1127243	c.2502T>C	p.N834N	Substitution - coding silent	Prostate
COSM285641	c.1810A>G	p.T604A	Substitution - Missense	Large_intestine
COSM5825019	c.915+1G>C	p.?	Unknown	Pancreas
COSM3863723	c.488G>A	p.R163Q	Substitution - Missense	Skin
COSM225830	c.1579C>T	p.Q527*	Substitution - Nonsense	Skin
COSM677839	c.1605G>T	p.R535S	Substitution - Missense	Lung
COSM4025607	c.795G>A	p.E265E	Substitution - coding silent	Stomach
COSM1689314	c.1480G>A	p.D494N	Substitution - Missense	Skin
COSM340540	c.1511T>C	p.I504T	Substitution - Missense	Lung
COSM4978974	c.1043T>C	p.L348P	Substitution - Missense	Oesophagus
COSM900300	c.1498G>A	p.E500K	Substitution - Missense	Endometrium
COSM3479279	c.747G>A	p.P249P	Substitution - coding silent	Oesophagus
COSM900308	c.2477G>T	p.R826M	Substitution - Missense	Endometrium
COSM3479291	c.1115C>T	p.P372L	Substitution - Missense	Skin
COSM4732906	c.1645C>T	p.R549*	Substitution - Nonsense	Large_intestine
COSM5378663	c.792G>A	p.V264V	Substitution - coding silent	Skin
COSM5496812	c.629G>A	p.G210E	Substitution - Missense	Biliary_tract
COSM5687161	c.2545T>A	p.C849S	Substitution - Missense	Soft_tissue
COSM1336717	c.1927G>A	p.E643K	Substitution - Missense	Central_nervous_system
COSM3863725	c.575G>A	p.R192K	Substitution - Missense	Skin
COSM4956739	c.356G>T	p.R119L	Substitution - Missense	Liver
COSM424702	c.1440C>A	p.I480I	Substitution - coding silent	Large_intestine
COSM3479279	c.747G>A	p.P249P	Substitution - coding silent	Skin
COSM463497	c.702A>G	p.V234V	Substitution - coding silent	Kidney
COSM342319	c.828C>A	p.N276K	Substitution - Missense	Lung
COSM3479293	c.1225C>T	p.P409S	Substitution - Missense	Skin
COSM677832	c.2482C>T	p.Q828*	Substitution - Nonsense	Lung
COSM2095524	c.1677C>A	p.F559L	Substitution - Missense	Large_intestine
COSM3976617	c.123C>A	p.N41K	Substitution - Missense	Lung
COSM5037935	c.345G>A	p.P115P	Substitution - coding silent	Skin
COSM3803004	c.851C>T	p.S284L	Substitution - Missense	Breast
COSM343273	c.70G>A	p.D24N	Substitution - Missense	Lung
COSM4399827	c.1844G>A	p.C615Y	Substitution - Missense	Skin
COSM5894236	c.1753C>T	p.P585S	Substitution - Missense	Skin
COSM228823	c.2161-1G>A	p.?	Unknown	Skin
COSM2095543	c.2002-1G>A	p.?	Unknown	Skin
COSM3803008	c.1014C>A	p.F338L	Substitution - Missense	Breast
COSM3863721	c.244G>A	p.E82K	Substitution - Missense	Skin
COSM3863736	c.1941C>T	p.F647F	Substitution - coding silent	Skin
COSM900302	c.1814C>T	p.S605L	Substitution - Missense	Large_intestine
COSM39390	c.2774G>A	p.R925H	Substitution - Missense	Central_nervous_system
COSM3750651	c.1362C>T	p.D454D	Substitution - coding silent	Large_intestine
COSM3479325	c.2344G>A	p.D782N	Substitution - Missense	Skin
COSM900299	c.1458C>A	p.F486L	Substitution - Missense	Endometrium
COSM5723506	c.1217G>A	p.W406*	Substitution - Nonsense	Skin
COSM3934295	c.665G>C	p.R222T	Substitution - Missense	Oesophagus
COSM1336706	c.193C>T	p.R65C	Substitution - Missense	Central_nervous_system
COSM1295552	c.1798G>C	p.E600Q	Substitution - Missense	Urinary_tract
COSM3479277	c.616G>A	p.E206K	Substitution - Missense	Skin
COSM3479277	c.616G>A	p.E206K	Substitution - Missense	Biliary_tract
COSM463499	c.1975G>C	p.V659L	Substitution - Missense	Kidney
COSM900304	c.2130A>G	p.P710P	Substitution - coding silent	Endometrium
COSM1689314	c.1480G>A	p.D494N	Substitution - Missense	Skin
COSM3479327	c.2380G>A	p.D794N	Substitution - Missense	Skin
COSM4025614	c.1845C>T	p.C615C	Substitution - coding silent	Stomach
COSM5605107	c.624G>A	p.P208P	Substitution - coding silent	Skin
COSM1689318	c.2768A>T	p.D923V	Substitution - Missense	Skin
COSM531051	c.2190G>T	p.L730L	Substitution - coding silent	Skin
COSM900298	c.950C>A	p.S317Y	Substitution - Missense	Endometrium
COSM3479342	c.2700G>A	p.V900V	Substitution - coding silent	Skin
COSM4788734	c.1955G>A	p.R652K	Substitution - Missense	Liver
COSM5378659	c.271G>A	p.V91I	Substitution - Missense	Skin
COSM5723506	c.1217G>A	p.W406*	Substitution - Nonsense	Skin
COSM221930	c.2536G>A	p.E846K	Substitution - Missense	Skin
COSM3369432	c.1600G>A	p.V534I	Substitution - Missense	Thyroid
COSM2095476	c.87G>T	p.Q29H	Substitution - Missense	Large_intestine
COSM677838	c.1654G>C	p.E552Q	Substitution - Missense	Lung
COSM900290	c.12A>C	p.Q4H	Substitution - Missense	Endometrium
COSM3479334	c.2675C>T	p.S892F	Substitution - Missense	Skin
COSM4788457	c.2063T>C	p.I688T	Substitution - Missense	Liver
COSM4919465	c.1130A>T	p.Q377L	Substitution - Missense	Liver
COSM5673924	c.386C>A	p.P129H	Substitution - Missense	Soft_tissue
COSM3479295	c.1257G>T	p.K419N	Substitution - Missense	Skin
COSM1689315	c.1834C>T	p.Q612*	Substitution - Nonsense	Skin
COSM5671946	c.1567G>T	p.E523*	Substitution - Nonsense	Soft_tissue
COSM5631222	c.2208T>G	p.G736G	Substitution - coding silent	Oesophagus
COSM5719423	c.2007C>T	p.F669F	Substitution - coding silent	Skin
COSM677833	c.2272G>A	p.A758T	Substitution - Missense	Lung
COSM1336716	c.1901delT	p.L636fs*16	Deletion - Frameshift	Biliary_tract
COSM1668243	c.1207G>T	p.E403*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM386187	c.2435C>A	p.P812Q	Substitution - Missense	Lung
COSM3803006	c.860C>T	p.A287V	Substitution - Missense	Breast
COSM5719423	c.2007C>T	p.F669F	Substitution - coding silent	Skin
COSM677842	c.1497C>A	p.L499L	Substitution - coding silent	Lung
COSM3863736	c.1941C>T	p.F647F	Substitution - coding silent	Skin
COSM383755	c.2685G>T	p.K895N	Substitution - Missense	Lung
COSM1560417	c.1229_1230insA	p.Q413fs*13	Insertion - Frameshift	Large_intestine
COSM5719425	c.2886G>T	p.R962R	Substitution - coding silent	Skin
COSM677828	c.2788G>T	p.D930Y	Substitution - Missense	Lung
COSM3750649	c.378G>C	p.R126S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5723508	c.2092C>T	p.Q698*	Substitution - Nonsense	Skin
COSM146701	c.2164G>A	p.E722K	Substitution - Missense	Stomach
COSM3771539	c.137G>A	p.R46Q	Substitution - Missense	Pancreas
COSM5052844	c.1230delA	p.K412fs*17	Deletion - Frameshift	Stomach
COSM4576628	c.1470C>A	p.I490I	Substitution - coding silent	Bone
COSM3479283	c.878G>A	p.G293E	Substitution - Missense	Skin
COSM5427676	c.1630C>T	p.R544W	Substitution - Missense	Breast
COSM290619	c.2885G>A	p.R962Q	Substitution - Missense	Large_intestine
COSM4788457	c.2063T>C	p.I688T	Substitution - Missense	Liver
COSM4025616	c.1846G>A	p.G616S	Substitution - Missense	Stomach
COSM4470136	c.1642C>T	p.H548Y	Substitution - Missense	Skin
COSM5556799	c.294T>A	p.H98Q	Substitution - Missense	Prostate
COSM4140979	c.1976T>A	p.V659E	Substitution - Missense	Kidney
COSM229898	c.1532C>T	p.S511F	Substitution - Missense	Skin
COSM5605105	c.198C>T	p.V66V	Substitution - coding silent	Skin
COSM1668244	c.1484C>T	p.S495L	Substitution - Missense	Skin
COSM3976619	c.248C>T	p.S83F	Substitution - Missense	Lung
COSM1336706	c.193C>T	p.R65C	Substitution - Missense	Skin
COSM344898	c.2835G>T	p.K945N	Substitution - Missense	Lung
COSM900292	c.246A>G	p.E82E	Substitution - coding silent	Endometrium
COSM4635877	c.2037G>A	p.T679T	Substitution - coding silent	Large_intestine
COSM5819706	c.2509T>A	p.S837T	Substitution - Missense	Liver
COSM900303	c.1994C>A	p.S665Y	Substitution - Missense	Endometrium
COSM5496810	c.460G>A	p.E154K	Substitution - Missense	Biliary_tract
COSM5378671	c.1767C>T	p.I589I	Substitution - coding silent	Skin
COSM5562951	c.2237C>G	p.P746R	Substitution - Missense	Prostate
COSM5431046	c.796A>C	p.T266P	Substitution - Missense	Oesophagus
COSM3479271	c.302G>A	p.R101Q	Substitution - Missense	Skin
COSM3479346	c.2897C>T	p.S966F	Substitution - Missense	Skin
COSM221311	c.622C>A	p.P208T	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM2095548	c.2152C>T	p.R718C	Substitution - Missense	Urinary_tract
COSM3479342	c.2700G>A	p.V900V	Substitution - coding silent	Skin
COSM4895927	c.846C>T	p.F282F	Substitution - coding silent	Skin
COSM5719425	c.2886G>T	p.R962R	Substitution - coding silent	Skin
COSM5072049	c.2593G>A	p.E865K	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5930765	c.2011G>A	p.E671K	Substitution - Missense	Skin
COSM677847	c.193C>A	p.R65S	Substitution - Missense	Lung
COSM3863716	c.47G>A	p.R16K	Substitution - Missense	Skin
COSM3479269	c.142C>T	p.L48F	Substitution - Missense	Skin
COSM4025618	c.2343+1G>T	p.?	Unknown	Stomach
COSM3976623	c.973-5G>T	p.?	Unknown	Lung
COSM1228830	c.1614G>T	p.E538D	Substitution - Missense	Kidney
COSM3997097	c.1596T>C	p.C532C	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM4572411	c.737T>G	p.M246R	Substitution - Missense	Skin
COSM2095567	c.2548A>G	p.T850A	Substitution - Missense	Large_intestine
COSM4852826	c.2815G>C	p.E939Q	Substitution - Missense	Cervix
COSM5378661	c.739G>A	p.E247K	Substitution - Missense	Skin
COSM386186	c.1539G>C	p.Q513H	Substitution - Missense	Lung
COSM3479287	c.981T>C	p.F327F	Substitution - coding silent	Skin
COSM4945224	c.1005A>C	p.K335N	Substitution - Missense	Testis
COSM1336717	c.1927G>A	p.E643K	Substitution - Missense	Skin
COSM3479285	c.880A>G	p.T294A	Substitution - Missense	Skin
COSM3732000	c.2858C>T	p.A953V	Substitution - Missense	Stomach
COSM1166319	c.301C>T	p.R101*	Substitution - Nonsense	Large_intestine
COSM3479269	c.142C>T	p.L48F	Substitution - Missense	Skin
COSM1689310	c.40G>A	p.E14K	Substitution - Missense	Skin
COSM1336706	c.193C>T	p.R65C	Substitution - Missense	Large_intestine
COSM4836979	c.228G>A	p.L76L	Substitution - coding silent	Cervix
COSM129642	c.2780A>T	p.E927V	Substitution - Missense	Upper_aerodigestive_tract
COSM2095514	c.1006T>A	p.L336I	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1267584	c.2731G>A	p.D911N	Substitution - Missense	Oesophagus
COSM5960728	c.1962G>A	p.E654E	Substitution - coding silent	Breast
COSM3479323	c.2307G>A	p.K769K	Substitution - coding silent	Skin
COSM900310	c.2884C>T	p.R962W	Substitution - Missense	Endometrium
COSM4915573	c.2153G>A	p.R718H	Substitution - Missense	Liver
COSM1689311	c.118G>A	p.G40S	Substitution - Missense	Skin
COSM3863734	c.1691G>A	p.G564E	Substitution - Missense	Skin
COSM1336719	c.2209G>A	p.D737N	Substitution - Missense	Skin
COSM5723506	c.1217G>A	p.W406*	Substitution - Nonsense	Skin
COSM3863731	c.1284A>T	p.V428V	Substitution - coding silent	Skin
COSM3479277	c.616G>A	p.E206K	Substitution - Missense	Skin
COSM334219	c.421G>T	p.D141Y	Substitution - Missense	Lung
COSM4416798	c.1072A>G	p.K358E	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1228829	c.542C>T	p.A181V	Substitution - Missense	Large_intestine
COSM4416352	c.1113G>A	p.K371K	Substitution - coding silent	Thyroid
COSM1336719	c.2209G>A	p.D737N	Substitution - Missense	Large_intestine
COSM900309	c.2745C>T	p.S915S	Substitution - coding silent	Endometrium
COSM3705284	c.2343+9C>T	p.?	Unknown	Liver
COSM5378667	c.1126+1G>A	p.?	Unknown	Skin
COSM3863727	c.1129C>T	p.Q377*	Substitution - Nonsense	Skin
COSM129643	c.2881G>C	p.A961P	Substitution - Missense	Upper_aerodigestive_tract
COSM677848	c.190G>T	p.V64F	Substitution - Missense	Lung
COSM4418969	c.2397A>G	p.S799S	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM2095492	c.584C>A	p.S195Y	Substitution - Missense	Large_intestine
COSM677843	c.1467G>T	p.R489R	Substitution - coding silent	Lung
COSM677826	c.2921C>A	p.P974H	Substitution - Missense	Lung
COSM39390	c.2774G>A	p.R925H	Substitution - Missense	Ovary
COSM4025612	c.1077A>G	p.G359G	Substitution - coding silent	Stomach
COSM4938991	c.800C>G	p.S267*	Substitution - Nonsense	Liver
COSM108352	c.39G>A	p.K13K	Substitution - coding silent	Skin
COSM4429359	c.699G>A	p.P233P	Substitution - coding silent	Oesophagus
COSM5586772	c.634C>T	p.P212S	Substitution - Missense	Skin
COSM5037935	c.345G>A	p.P115P	Substitution - coding silent	Large_intestine
COSM1664511	c.2711C>G	p.P904R	Substitution - Missense	Kidney
COSM3479297	c.1412C>T	p.S471F	Substitution - Missense	Skin
COSM5593412	c.495C>T	p.F165F	Substitution - coding silent	Skin
COSM4438245	c.1253A>T	p.Q418L	Substitution - Missense	Oesophagus
COSM4554629	c.626G>A	p.R209K	Substitution - Missense	Skin
COSM1288405	c.1501G>T	p.D501Y	Substitution - Missense	Autonomic_ganglia
COSM424704	c.2368G>A	p.D790N	Substitution - Missense	Breast
COSM3479313	c.2190G>A	p.L730L	Substitution - coding silent	Skin
COSM3418419	c.1552C>T	p.R518*	Substitution - Nonsense	Skin
COSM1336716	c.1901delT	p.L636fs*16	Deletion - Frameshift	Large_intestine
COSM3479342	c.2700G>A	p.V900V	Substitution - coding silent	Skin
COSM3479303	c.1876G>A	p.E626K	Substitution - Missense	Skin
COSM3418419	c.1552C>T	p.R518*	Substitution - Nonsense	Large_intestine
COSM4998999	c.2836C>T	p.L946F	Substitution - Missense	Pancreas
COSM5582741	c.1464C>T	p.I488I	Substitution - coding silent	Skin
COSM463500	c.2193G>T	p.E731D	Substitution - Missense	Kidney
COSM3479318	c.2220G>A	p.W740*	Substitution - Nonsense	Skin
COSM5926312	c.2183C>T	p.P728L	Substitution - Missense	Skin
COSM5694528	c.1434G>T	p.E478D	Substitution - Missense	Soft_tissue
COSM5378665	c.937G>A	p.G313S	Substitution - Missense	Skin
COSM349882	c.2593G>C	p.E865Q	Substitution - Missense	Lung
COSM36638	c.1482T>C	p.D494D	Substitution - coding silent	Skin
COSM323775	c.2632C>A	p.L878I	Substitution - Missense	Lung
COSM3479297	c.1412C>T	p.S471F	Substitution - Missense	Skin
COSM5719423	c.2007C>T	p.F669F	Substitution - coding silent	Skin
COSM5723508	c.2092C>T	p.Q698*	Substitution - Nonsense	Skin
COSM5659825	c.2321C>G	p.S774*	Substitution - Nonsense	Soft_tissue
COSM1668243	c.1207G>T	p.E403*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM3479342	c.2700G>A	p.V900V	Substitution - coding silent	Skin
COSM3385471	c.2747G>A	p.R916H	Substitution - Missense	Pancreas
COSM3479265	c.100G>A	p.E34K	Substitution - Missense	Skin
COSM3479316	c.2212G>A	p.D738N	Substitution - Missense	Skin
COSM677845	c.637G>C	p.A213P	Substitution - Missense	Lung
COSM5723506	c.1217G>A	p.W406*	Substitution - Nonsense	Skin
COSM3750649	c.378G>C	p.R126S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3849335	c.1583C>T	p.P528L	Substitution - Missense	Pancreas
COSM1336710	c.1049A>T	p.D350V	Substitution - Missense	Large_intestine
COSM3479283	c.878G>A	p.G293E	Substitution - Missense	Skin
COSM3479344	c.2718C>T	p.I906I	Substitution - coding silent	Skin
COSM3479307	c.1992C>T	p.I664I	Substitution - coding silent	Skin
COSM5074000	c.1356G>A	p.P452P	Substitution - coding silent	Oesophagus
COSM221930	c.2536G>A	p.E846K	Substitution - Missense	Skin
COSM300813	c.2662G>T	p.A888S	Substitution - Missense	Large_intestine
COSM4622317	c.2668G>T	p.D890Y	Substitution - Missense	Large_intestine
COSM343273	c.70G>A	p.D24N	Substitution - Missense	Skin
COSM5649079	c.2928G>A	p.V976V	Substitution - coding silent	Oesophagus
COSM4545176	c.371G>A	p.R124Q	Substitution - Missense	Skin
COSM5637728	c.1982G>A	p.R661Q	Substitution - Missense	Oesophagus
COSM3479275	c.439C>T	p.P147S	Substitution - Missense	Skin
COSM137792	c.1243G>A	p.E415K	Substitution - Missense	Skin
COSM3479279	c.747G>A	p.P249P	Substitution - coding silent	Skin
COSM5993374	c.51A>T	p.S17S	Substitution - coding silent	Prostate
COSM1689313	c.1478G>A	p.R493K	Substitution - Missense	Skin
COSM677849	c.20T>C	p.I7T	Substitution - Missense	Lung
COSM5562325	c.1173A>G	p.P391P	Substitution - coding silent	Prostate
COSM677841	c.1604G>A	p.R535K	Substitution - Missense	Lung
COSM4935549	c.357G>A	p.R119R	Substitution - coding silent	Liver
COSM1582219	c.640+4C>T	p.?	Unknown	Stomach
COSM3750651	c.1362C>T	p.D454D	Substitution - coding silent	Thyroid
COSM3984512	c.1589A>C	p.H530P	Substitution - Missense	Kidney
COSM3479309	c.2169C>T	p.I723I	Substitution - coding silent	Skin
COSM5352568	c.767delA	p.K257fs*5	Deletion - Frameshift	Large_intestine
COSM4846960	c.885C>G	p.I295M	Substitution - Missense	Cervix
COSM3976627	c.2153G>T	p.R718L	Substitution - Missense	Lung
COSM1668244	c.1484C>T	p.S495L	Substitution - Missense	Large_intestine
COSM1689319	c.2849G>A	p.R950Q	Substitution - Missense	Skin
COSM1290056	c.2272G>C	p.A758P	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3418417	c.136C>T	p.R46*	Substitution - Nonsense	Oesophagus
COSM4476671	c.2086C>T	p.P696S	Substitution - Missense	Skin
COSM1336717	c.1927G>A	p.E643K	Substitution - Missense	Large_intestine
COSM3943152	c.961G>A	p.G321R	Substitution - Missense	Ovary
COSM3479342	c.2700G>A	p.V900V	Substitution - coding silent	Skin
COSM3479329	c.2401C>T	p.L801F	Substitution - Missense	Skin
COSM1689312	c.869G>A	p.G290E	Substitution - Missense	Skin
COSM1288406	c.377G>T	p.R126M	Substitution - Missense	Autonomic_ganglia
COSM4451215	c.1109A>G	p.K370R	Substitution - Missense	Skin
COSM4143074	c.394C>T	p.P132S	Substitution - Missense	Thyroid
COSM3479332	c.2649C>T	p.P883P	Substitution - coding silent	Skin
COSM3863734	c.1691G>A	p.G564E	Substitution - Missense	Skin
COSM3479321	c.2294G>A	p.S765N	Substitution - Missense	Skin
COSM3479305	c.1893C>T	p.I631I	Substitution - coding silent	Skin
COSM4416352	c.1113G>A	p.K371K	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM1689317	c.2410G>A	p.G804R	Substitution - Missense	Skin
COSM80621	c.1728C>T	p.F576F	Substitution - coding silent	Ovary
COSM4902918	c.1509G>A	p.M503I	Substitution - Missense	Skin
COSM3360519	c.15G>T	p.E5D	Substitution - Missense	Kidney
COSM4576630	c.2204T>C	p.I735T	Substitution - Missense	Bone
COSM900302	c.1814C>T	p.S605L	Substitution - Missense	Large_intestine
COSM3730597	c.1981C>T	p.R661*	Substitution - Nonsense	Stomach
COSM1320700	c.1885G>A	p.D629N	Substitution - Missense	Ovary
COSM1668244	c.1484C>T	p.S495L	Substitution - Missense	Skin
COSM677827	c.2807T>A	p.L936*	Substitution - Nonsense	Lung
COSM5468902	c.751C>T	p.Q251*	Substitution - Nonsense	Large_intestine
COSM3479299	c.1445C>T	p.S482F	Substitution - Missense	Skin
COSM3479316	c.2212G>A	p.D738N	Substitution - Missense	Skin
COSM1185669	c.2710C>A	p.P904T	Substitution - Missense	Lung
COSM424703	c.1734G>A	p.K578K	Substitution - coding silent	Breast
COSM5423151	c.1370C>T	p.P457L	Substitution - Missense	Prostate
COSM1166319	c.301C>T	p.R101*	Substitution - Nonsense	Large_intestine
COSM900293	c.539A>G	p.N180S	Substitution - Missense	Endometrium
COSM677841	c.1604G>A	p.R535K	Substitution - Missense	Skin
COSM424702	c.1440C>A	p.I480I	Substitution - coding silent	Breast
COSM1336720	c.2773C>T	p.R925C	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4896387	c.1392C>T	p.L464L	Substitution - coding silent	Skin
COSM5577796	c.2533T>A	p.L845M	Substitution - Missense	Skin
COSM3479281	c.768A>T	p.E256D	Substitution - Missense	Skin
COSM900302	c.1814C>T	p.S605L	Substitution - Missense	Endometrium
COSM5993374	c.51A>T	p.S17S	Substitution - coding silent	Prostate
COSM2095561	c.2260G>A	p.G754R	Substitution - Missense	Skin
COSM5930767	c.731C>T	p.S244L	Substitution - Missense	Skin
COSM4920448	c.2751T>C	p.A917A	Substitution - coding silent	Liver
COSM4999664	c.2663C>A	p.A888E	Substitution - Missense	Pancreas
COSM424705	c.2437G>C	p.E813Q	Substitution - Missense	Breast
COSM1336717	c.1927G>A	p.E643K	Substitution - Missense	Skin
COSM1733634	c.1483T>C	p.S495P	Substitution - Missense	Pancreas
COSM3479267	c.115G>A	p.V39I	Substitution - Missense	Skin
COSM3849335	c.1583C>T	p.P528L	Substitution - Missense	Pancreas
COSM226478	c.1663G>A	p.E555K	Substitution - Missense	Skin
COSM3803010	c.1247C>T	p.P416L	Substitution - Missense	Breast
COSM5605103	c.1057C>T	p.H353Y	Substitution - Missense	Skin
COSM3479283	c.878G>A	p.G293E	Substitution - Missense	Skin
COSM5723508	c.2092C>T	p.Q698*	Substitution - Nonsense	Skin
COSM900307	c.2452C>T	p.Q818*	Substitution - Nonsense	Endometrium
COSM5378669	c.1425C>T	p.V475V	Substitution - coding silent	Skin
COSM5491234	c.2616G>A	p.Q872Q	Substitution - coding silent	Biliary_tract
COSM1166319	c.301C>T	p.R101*	Substitution - Nonsense	Large_intestine
COSM4788734	c.1955G>A	p.R652K	Substitution - Missense	Liver
COSM1336707	c.452C>A	p.S151Y	Substitution - Missense	Large_intestine
COSM5820673	c.117T>A	p.V39V	Substitution - coding silent	Liver
COSM347443	c.1985A>G	p.E662G	Substitution - Missense	Lung
COSM4185679	c.2193G>C	p.E731D	Substitution - Missense	Kidney
COSM3479283	c.878G>A	p.G293E	Substitution - Missense	Skin
COSM146701	c.2164G>A	p.E722K	Substitution - Missense	Thyroid
COSM4841123	c.550G>A	p.D184N	Substitution - Missense	Cervix
COSM1689316	c.2254G>A	p.G752R	Substitution - Missense	Skin
COSM4541313	c.2819G>A	p.C940Y	Substitution - Missense	Skin
COSM5597711	c.141C>T	p.I47I	Substitution - coding silent	Skin
COSM3479303	c.1876G>A	p.E626K	Substitution - Missense	Skin
COSM1336718	c.2182C>A	p.P728T	Substitution - Missense	Large_intestine
COSM424710	c.2758T>C	p.L920L	Substitution - coding silent	Breast
COSM3750649	c.378G>C	p.R126S	Substitution - Missense	Large_intestine
COSM1336717	c.1927G>A	p.E643K	Substitution - Missense	Skin
COSM346558	c.544G>T	p.A182S	Substitution - Missense	Lung
COSM5719423	c.2007C>T	p.F669F	Substitution - coding silent	Skin
COSM3863729	c.1184C>T	p.S395L	Substitution - Missense	Skin
COSM4619669	c.2675C>G	p.S892C	Substitution - Missense	Large_intestine
COSM5719425	c.2886G>T	p.R962R	Substitution - coding silent	Skin
COSM5719425	c.2886G>T	p.R962R	Substitution - coding silent	Skin
COSM463501	c.2596C>T	p.P866S	Substitution - Missense	Kidney
COSM4732901	c.1093G>A	p.V365M	Substitution - Missense	Large_intestine
COSM1336717	c.1927G>A	p.E643K	Substitution - Missense	Skin
COSM1689317	c.2410G>A	p.G804R	Substitution - Missense	Skin
COSM4418678	c.2052G>A	p.G684G	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM5656589	c.1519C>T	p.R507W	Substitution - Missense	Soft_tissue
COSM5025451	c.1497C>T	p.L499L	Substitution - coding silent	Breast
COSM1228830	c.1614G>T	p.E538D	Substitution - Missense	Large_intestine
COSM1747977	c.1172C>T	p.P391L	Substitution - Missense	Urinary_tract
COSM4943957	c.774T>A	p.T258T	Substitution - coding silent	Liver
COSM5612201	c.1435T>C	p.Y479H	Substitution - Missense	Adrenal_gland
COSM333350	c.1724G>A	p.R575K	Substitution - Missense	Lung
COSM3984514	c.2126G>T	p.S709I	Substitution - Missense	Kidney
COSM3863719	c.88G>A	p.E30K	Substitution - Missense	Skin
COSM900305	c.2208T>C	p.G736G	Substitution - coding silent	Endometrium
COSM900306	c.2344-1G>T	p.?	Unknown	Endometrium
COSM2095589	c.2746C>T	p.R916C	Substitution - Missense	Stomach
COSM3789166	c.1110G>A	p.K370K	Substitution - coding silent	Urinary_tract
COSM146701	c.2164G>A	p.E722K	Substitution - Missense	Large_intestine
COSM5378683	c.2846C>T	p.P949L	Substitution - Missense	Skin
COSM4464562	c.133C>G	p.L45V	Substitution - Missense	Skin
COSM4539112	c.2487G>A	p.K829K	Substitution - coding silent	Skin
COSM3479273	c.320G>A	p.G107E	Substitution - Missense	Skin
COSM1290055	c.2117G>A	p.R706Q	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM2095564	c.2415G>A	p.T805T	Substitution - coding silent	Stomach
COSM5507586	c.2236C>T	p.P746S	Substitution - Missense	Biliary_tract
COSM3479342	c.2700G>A	p.V900V	Substitution - coding silent	Skin
COSM5477829	c.1465C>T	p.R489W	Substitution - Missense	Large_intestine
COSM3479318	c.2220G>A	p.W740*	Substitution - Nonsense	Skin
COSM140391	c.214G>T	p.G72C	Substitution - Missense	Skin
COSM1747977	c.1172C>T	p.P391L	Substitution - Missense	Urinary_tract
COSM5452283	c.658C>A	p.P220T	Substitution - Missense	Large_intestine
COSM5993374	c.51A>T	p.S17S	Substitution - coding silent	Prostate
COSM3863738	c.2020C>T	p.P674S	Substitution - Missense	Skin
COSM4913065	c.1467G>C	p.R489R	Substitution - coding silent	Liver
COSM3479311	c.2187C>T	p.C729C	Substitution - coding silent	Skin
COSM5636659	c.2871A>C	p.L957F	Substitution - Missense	Oesophagus
COSM5676996	c.1716C>A	p.S572S	Substitution - coding silent	Soft_tissue
COSM5353790	c.1485G>A	p.S495S	Substitution - coding silent	Large_intestine
COSM900291	c.96G>T	p.E32D	Substitution - Missense	Endometrium

> Text Mining based Variations [ TOP ]
There is no record for TDRD5.

Summary
Symbol	TDRD5
Name	tudor domain containing 5
Aliases	FLJ34823; TUDOR3; Tudor domain-containing protein 5
Location	1q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

[ TOP ]

Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant

Summary
Symbol	TDRD5
Name	tudor domain containing 5
Aliases	FLJ34823; TUDOR3; Tudor domain-containing protein 5
Location	1q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	-2.021	0.999	2.489	0.00299	Over
BRCA	Breast invasive carcinoma	112	1100	2.629	3.186	0.638	0.00268	Over
CESC	Cervical and endocervical cancers	3	306	-4.489	0.027	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	-0.259	0.461	0.545	0.143	NS
ESCA	Esophageal carcinoma	11	185	-1.707	1.885	3.283	0.00167	Over
HNSC	Head and Neck squamous cell carcinoma	44	522	-2.124	-1.597	0.945	0.124	NS
KIRC	Kidney renal clear cell carcinoma	72	534	1.409	-4.253	-5.177	2.3e-60	Under
KIRP	Kidney renal papillary cell carcinoma	32	291	1.149	-2.357	-3.587	1.28e-13	Under
LGG	Brain Lower Grade Glioma	0	530	NA	-1.995	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	-5.999	-5.758	0.851	0.0229	Over
LUAD	Lung adenocarcinoma	59	517	-3.079	0.012	2.499	1.93e-08	Over
LUSC	Lung squamous cell carcinoma	51	501	-2.925	2.22	3.97	2.78e-18	Over
OV	Ovarian serous cystadenocarcinoma	0	307	NA	1.626	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	-1.443	-0.187	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	-3.306	-3.465	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	0.084	-0.135	-0.572	0.0656	NS
READ	Rectum adenocarcinoma	10	167	-0.994	0.541	1.087	0.154	NS
SARC	Sarcoma	2	263	-2.885	-5.279	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	-4.513	-5.628	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	-1.837	0.56	2.138	8.17e-05	Over
TGCT	Testicular Germ Cell Tumors	0	156	NA	1.882	NA	NA	NA
THCA	Thyroid carcinoma	59	509	0.376	-0.826	-1.484	6.1e-11	Under
THYM	Thymoma	2	120	-1.237	0.278	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	-2.24	0.266	1.963	4.03e-05	Over

> Cancer Cell Line Encyclopedia (CCLE)

[ TOP ]

Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	4.1
Autonomic ganglia	CHP212	3.9
Autonomic ganglia	IMR32	4.2
Autonomic ganglia	KELLY	4
Autonomic ganglia	KPNRTBM1	3.9
Autonomic ganglia	KPNSI9S	4
Autonomic ganglia	KPNYN	4
Autonomic ganglia	MHHNB11	4
Autonomic ganglia	NB1	4.3
Autonomic ganglia	NH6	3.9
Autonomic ganglia	SHSY5Y	4.2
Autonomic ganglia	SIMA	4.3
Autonomic ganglia	SKNAS	4.4
Autonomic ganglia	SKNBE2	4.2
Autonomic ganglia	SKNDZ	4.2
Autonomic ganglia	SKNFI	4.2
Autonomic ganglia	SKNSH	4.1
Biliary tract	HUCCT1	4.5
Biliary tract	HUH28	4.1
Biliary tract	SNU1079	4.3
Biliary tract	SNU1196	4.4
Biliary tract	SNU245	4.1
Biliary tract	SNU308	4.2
Biliary tract	SNU478	4.2
Bone	143B	4.1
Bone	A673	4.3
Bone	CADOES1	4.1
Bone	CAL78	3.8
Bone	G292CLONEA141B1	4.2
Bone	HOS	4.1
Bone	HS706T	4
Bone	HS737T	4.6
Bone	HS819T	4.4
Bone	HS821T	4.2
Bone	HS822T	4.1
Bone	HS863T	4
Bone	HS870T	4.2
Bone	HS888T	3.7
Bone	MG63	3.9
Bone	MHHES1	4
Bone	OUMS27	4
Bone	RDES	4
Bone	SJSA1	3.9
Bone	SKES1	4
Bone	SKNMC	4.7
Bone	SW1353	4.2
Bone	T173	4.1
Bone	TC71	4.6
Bone	U2OS	4.9
Breast	AU565	5.2
Breast	BT20	5.6
Breast	BT474	4.2
Breast	BT483	5.2
Breast	BT549	4.3
Breast	CAL120	4.2
Breast	CAL148	5.4
Breast	CAL51	4.2
Breast	CAL851	5.2
Breast	CAMA1	5.5
Breast	DU4475	7.2
Breast	EFM192A	4.6
Breast	EFM19	5.9
Breast	EVSAT	4.6
Breast	HCC1143	4
Breast	HCC1187	4.9
Breast	HCC1395	3.9
Breast	HCC1419	4.2
Breast	HCC1428	5
Breast	HCC1500	4.1
Breast	HCC1569	4
Breast	HCC1599	4.2
Breast	HCC1806	4
Breast	HCC1937	4.4
Breast	HCC1954	4.3
Breast	HCC202	6.4
Breast	HCC2157	6.1
Breast	HCC2218	4.6
Breast	HCC38	6.5
Breast	HCC70	4.8
Breast	HDQP1	4.8
Breast	HMC18	4.3
Breast	HS274T	4.1
Breast	HS281T	3.8
Breast	HS343T	4.1
Breast	HS578T	4.4
Breast	HS606T	4
Breast	HS739T	3.9
Breast	HS742T	4.3
Breast	JIMT1	4.1
Breast	KPL1	5.7
Breast	MCF7	5.2
Breast	MDAMB134VI	4.3
Breast	MDAMB157	4.2
Breast	MDAMB175VII	4.9
Breast	MDAMB231	4.2
Breast	MDAMB361	4.4
Breast	MDAMB415	5
Breast	MDAMB436	3.7
Breast	MDAMB453	5.2
Breast	MDAMB468	5
Breast	SKBR3	5.4
Breast	T47D	7
Breast	UACC812	5.7
Breast	UACC893	6.9
Breast	YMB1	5.9
Breast	ZR751	5.4
Breast	ZR7530	4.5
Central nervous system	1321N1	4
Central nervous system	42MGBA	4.2
Central nervous system	8MGBA	3.8
Central nervous system	A172	3.9
Central nervous system	AM38	4
Central nervous system	BECKER	4
Central nervous system	CAS1	4
Central nervous system	CCFSTTG1	4.3
Central nervous system	D283MED	4.5
Central nervous system	D341MED	4.2
Central nervous system	DAOY	3.9
Central nervous system	DBTRG05MG	4.2
Central nervous system	DKMG	3.7
Central nervous system	GAMG	4.1
Central nervous system	GB1	4
Central nervous system	GI1	4.2
Central nervous system	GMS10	4
Central nervous system	GOS3	4.1
Central nervous system	H4	4.4
Central nervous system	HS683	3.9
Central nervous system	KALS1	4
Central nervous system	KG1C	4.1
Central nervous system	KNS42	4.4
Central nervous system	KNS60	5
Central nervous system	KNS81	3.9
Central nervous system	KS1	4.2
Central nervous system	LN18	4
Central nervous system	LN229	4.3
Central nervous system	M059K	4.6
Central nervous system	MOGGCCM	4.3
Central nervous system	MOGGUVW	4
Central nervous system	NMCG1	3.8
Central nervous system	ONS76	5.7
Central nervous system	SF126	4.4
Central nervous system	SF295	4.2
Central nervous system	SNB19	4
Central nervous system	SNU1105	4.1
Central nervous system	SNU201	3.8
Central nervous system	SNU466	3.9
Central nervous system	SNU489	3.9
Central nervous system	SNU626	3.9
Central nervous system	SNU738	3.9
Central nervous system	SW1088	4.1
Central nervous system	SW1783	3.8
Central nervous system	T98G	4.3
Central nervous system	TM31	4.1
Central nervous system	U118MG	3.9
Central nervous system	U138MG	4
Central nervous system	U251MG	3.8
Central nervous system	U87MG	4.3
Central nervous system	YH13	4
Central nervous system	YKG1	4
Endometrium	AN3CA	4.5
Endometrium	COLO684	4.1
Endometrium	EFE184	4.8
Endometrium	EN	4
Endometrium	ESS1	3.7
Endometrium	HEC108	3.9
Endometrium	HEC151	4.2
Endometrium	HEC1A	4
Endometrium	HEC1B	4.1
Endometrium	HEC251	6.2
Endometrium	HEC265	4.7
Endometrium	HEC50B	4.1
Endometrium	HEC59	3.9
Endometrium	HEC6	4
Endometrium	ISHIKAWAHERAKLIO02ER	4.2
Endometrium	JHUEM1	5
Endometrium	JHUEM2	4.2
Endometrium	JHUEM3	4.1
Endometrium	KLE	4.3
Endometrium	MFE280	4
Endometrium	MFE296	4.3
Endometrium	MFE319	4.1
Endometrium	RL952	4.1
Endometrium	SNGM	3.8
Endometrium	SNU1077	3.9
Endometrium	SNU685	3.8
Endometrium	TEN	4.2
Haematopoietic and lymphoid	697	3.9
Haematopoietic and lymphoid	A3KAW	4.5
Haematopoietic and lymphoid	A4FUK	4.2
Haematopoietic and lymphoid	ALLSIL	4.2
Haematopoietic and lymphoid	AML193	4
Haematopoietic and lymphoid	AMO1	4
Haematopoietic and lymphoid	BCP1	4.1
Haematopoietic and lymphoid	BDCM	4
Haematopoietic and lymphoid	BL41	4.1
Haematopoietic and lymphoid	BL70	4.4
Haematopoietic and lymphoid	BV173	4.4
Haematopoietic and lymphoid	CA46	4.4
Haematopoietic and lymphoid	CI1	4.1
Haematopoietic and lymphoid	CMK115	3.8
Haematopoietic and lymphoid	CMK86	3.9
Haematopoietic and lymphoid	CMK	4.2
Haematopoietic and lymphoid	CMLT1	7.2
Haematopoietic and lymphoid	COLO775	4.4
Haematopoietic and lymphoid	DAUDI	4
Haematopoietic and lymphoid	DB	4.3
Haematopoietic and lymphoid	DEL	3.9
Haematopoietic and lymphoid	DND41	4
Haematopoietic and lymphoid	DOHH2	4.5
Haematopoietic and lymphoid	EB1	4.5
Haematopoietic and lymphoid	EB2	4.2
Haematopoietic and lymphoid	EHEB	4.2
Haematopoietic and lymphoid	EJM	4.1
Haematopoietic and lymphoid	EM2	4.1
Haematopoietic and lymphoid	EOL1	4
Haematopoietic and lymphoid	F36P	3.7
Haematopoietic and lymphoid	GA10	4.3
Haematopoietic and lymphoid	GDM1	4.1
Haematopoietic and lymphoid	GRANTA519	4.2
Haematopoietic and lymphoid	HDLM2	4.1
Haematopoietic and lymphoid	HDMYZ	4.1
Haematopoietic and lymphoid	HEL9217	4.3
Haematopoietic and lymphoid	HEL	4.1
Haematopoietic and lymphoid	HH	4.3
Haematopoietic and lymphoid	HL60	4.4
Haematopoietic and lymphoid	HPBALL	4.3
Haematopoietic and lymphoid	HS604T	4.2
Haematopoietic and lymphoid	HS611T	4
Haematopoietic and lymphoid	HS616T	4.3
Haematopoietic and lymphoid	HS751T	3.8
Haematopoietic and lymphoid	HT	4.4
Haematopoietic and lymphoid	HTK	4.2
Haematopoietic and lymphoid	HUNS1	4.4
Haematopoietic and lymphoid	HUT102	3.7
Haematopoietic and lymphoid	HUT78	4.6
Haematopoietic and lymphoid	JEKO1	4
Haematopoietic and lymphoid	JK1	4.3
Haematopoietic and lymphoid	JM1	4.2
Haematopoietic and lymphoid	JURKAT	3.8
Haematopoietic and lymphoid	JURLMK1	4.3
Haematopoietic and lymphoid	JVM2	3.8
Haematopoietic and lymphoid	JVM3	4.2
Haematopoietic and lymphoid	K562	5.1
Haematopoietic and lymphoid	KARPAS299	4.2
Haematopoietic and lymphoid	KARPAS422	4.3
Haematopoietic and lymphoid	KARPAS620	4
Haematopoietic and lymphoid	KASUMI1	3.9
Haematopoietic and lymphoid	KASUMI2	4
Haematopoietic and lymphoid	KASUMI6	4.2
Haematopoietic and lymphoid	KCL22	4
Haematopoietic and lymphoid	KE37	4.3
Haematopoietic and lymphoid	KE97	3.8
Haematopoietic and lymphoid	KG1	4.4
Haematopoietic and lymphoid	KHM1B	4.7
Haematopoietic and lymphoid	KIJK	4.5
Haematopoietic and lymphoid	KMH2	5.2
Haematopoietic and lymphoid	KMM1	4.7
Haematopoietic and lymphoid	KMS11	4
Haematopoietic and lymphoid	KMS12BM	4
Haematopoietic and lymphoid	KMS18	3.7
Haematopoietic and lymphoid	KMS20	6.8
Haematopoietic and lymphoid	KMS21BM	5.9
Haematopoietic and lymphoid	KMS26	4.5
Haematopoietic and lymphoid	KMS27	4
Haematopoietic and lymphoid	KMS28BM	4.2
Haematopoietic and lymphoid	KMS34	4.2
Haematopoietic and lymphoid	KO52	3.8
Haematopoietic and lymphoid	KOPN8	4.4
Haematopoietic and lymphoid	KU812	4.1
Haematopoietic and lymphoid	KYO1	4.2
Haematopoietic and lymphoid	L1236	4.2
Haematopoietic and lymphoid	L363	4.4
Haematopoietic and lymphoid	L428	4.3
Haematopoietic and lymphoid	L540	4
Haematopoietic and lymphoid	LAMA84	4.2
Haematopoietic and lymphoid	LOUCY	4.1
Haematopoietic and lymphoid	LP1	4.1
Haematopoietic and lymphoid	M07E	3.8
Haematopoietic and lymphoid	MC116	4.5
Haematopoietic and lymphoid	ME1	4.3
Haematopoietic and lymphoid	MEC1	4.3
Haematopoietic and lymphoid	MEC2	4.3
Haematopoietic and lymphoid	MEG01	4.2
Haematopoietic and lymphoid	MHHCALL2	4.1
Haematopoietic and lymphoid	MHHCALL3	3.8
Haematopoietic and lymphoid	MHHCALL4	3.9
Haematopoietic and lymphoid	MINO	3.9
Haematopoietic and lymphoid	MJ	4.2
Haematopoietic and lymphoid	MM1S	4.1
Haematopoietic and lymphoid	MOLM13	4
Haematopoietic and lymphoid	MOLM16	3.9
Haematopoietic and lymphoid	MOLM6	4.3
Haematopoietic and lymphoid	MOLP2	6.4
Haematopoietic and lymphoid	MOLP8	4.3
Haematopoietic and lymphoid	MOLT13	4.2
Haematopoietic and lymphoid	MOLT16	3.7
Haematopoietic and lymphoid	MOLT4	3.8
Haematopoietic and lymphoid	MONOMAC1	4.1
Haematopoietic and lymphoid	MONOMAC6	4.1
Haematopoietic and lymphoid	MOTN1	4.6
Haematopoietic and lymphoid	MUTZ5	4
Haematopoietic and lymphoid	MV411	4.2
Haematopoietic and lymphoid	NALM19	3.9
Haematopoietic and lymphoid	NALM1	3.9
Haematopoietic and lymphoid	NALM6	3.9
Haematopoietic and lymphoid	NAMALWA	4
Haematopoietic and lymphoid	NB4	4.2
Haematopoietic and lymphoid	NCIH929	4.8
Haematopoietic and lymphoid	NCO2	4.3
Haematopoietic and lymphoid	NOMO1	4
Haematopoietic and lymphoid	NUDHL1	4.2
Haematopoietic and lymphoid	NUDUL1	3.7
Haematopoietic and lymphoid	OCIAML2	6.1
Haematopoietic and lymphoid	OCIAML3	4.2
Haematopoietic and lymphoid	OCIAML5	4
Haematopoietic and lymphoid	OCILY10	4.4
Haematopoietic and lymphoid	OCILY19	4.4
Haematopoietic and lymphoid	OCILY3	4.3
Haematopoietic and lymphoid	OCIM1	3.7
Haematopoietic and lymphoid	OPM2	4.5
Haematopoietic and lymphoid	P12ICHIKAWA	4.6
Haematopoietic and lymphoid	P31FUJ	4
Haematopoietic and lymphoid	P3HR1	4.4
Haematopoietic and lymphoid	PCM6	4.1
Haematopoietic and lymphoid	PEER	4
Haematopoietic and lymphoid	PF382	4.1
Haematopoietic and lymphoid	PFEIFFER	4.1
Haematopoietic and lymphoid	PL21	3.7
Haematopoietic and lymphoid	RAJI	4.5
Haematopoietic and lymphoid	RCHACV	4.4
Haematopoietic and lymphoid	REC1	4.1
Haematopoietic and lymphoid	REH	4.4
Haematopoietic and lymphoid	RI1	4.1
Haematopoietic and lymphoid	RL	4.4
Haematopoietic and lymphoid	RPMI8226	4
Haematopoietic and lymphoid	RPMI8402	4.1
Haematopoietic and lymphoid	RS411	4
Haematopoietic and lymphoid	SEM	3.9
Haematopoietic and lymphoid	SET2	4
Haematopoietic and lymphoid	SIGM5	3.9
Haematopoietic and lymphoid	SKM1	4.4
Haematopoietic and lymphoid	SKMM2	4.1
Haematopoietic and lymphoid	SR786	4.2
Haematopoietic and lymphoid	ST486	4.8
Haematopoietic and lymphoid	SUDHL10	4.6
Haematopoietic and lymphoid	SUDHL1	4.4
Haematopoietic and lymphoid	SUDHL4	4.4
Haematopoietic and lymphoid	SUDHL5	3.9
Haematopoietic and lymphoid	SUDHL6	4.2
Haematopoietic and lymphoid	SUDHL8	4.6
Haematopoietic and lymphoid	SUPB15	4
Haematopoietic and lymphoid	SUPHD1	4.4
Haematopoietic and lymphoid	SUPM2	4
Haematopoietic and lymphoid	SUPT11	4.2
Haematopoietic and lymphoid	SUPT1	4.6
Haematopoietic and lymphoid	TALL1	3.9
Haematopoietic and lymphoid	TF1	4
Haematopoietic and lymphoid	THP1	4.1
Haematopoietic and lymphoid	TO175T	4.3
Haematopoietic and lymphoid	TOLEDO	4.2
Haematopoietic and lymphoid	U266B1	7.3
Haematopoietic and lymphoid	U937	4
Haematopoietic and lymphoid	UT7	3.9
Haematopoietic and lymphoid	WSUDLCL2	4.2
Kidney	769P	4
Kidney	786O	4.3
Kidney	A498	4.4
Kidney	A704	4.3
Kidney	ACHN	3.9
Kidney	BFTC909	4.1
Kidney	CAKI1	3.8
Kidney	CAKI2	3.8
Kidney	CAL54	3.7
Kidney	KMRC1	4.3
Kidney	KMRC20	3.9
Kidney	KMRC2	4
Kidney	KMRC3	3.9
Kidney	OSRC2	4.1
Kidney	RCC10RGB	3.9
Kidney	SNU1272	3.9
Kidney	SNU349	4.3
Kidney	TUHR10TKB	3.8
Kidney	TUHR14TKB	4.2
Kidney	TUHR4TKB	3.9
Kidney	VMRCRCW	4.8
Kidney	VMRCRCZ	4
Large intestine	C2BBE1	4
Large intestine	CCK81	4.3
Large intestine	CL11	4.8
Large intestine	CL14	4.4
Large intestine	CL34	4
Large intestine	CL40	4.8
Large intestine	COLO205	4.6
Large intestine	COLO320	4.6
Large intestine	COLO678	4
Large intestine	CW2	5.3
Large intestine	DLD1	4.1
Large intestine	GP2D	7.2
Large intestine	HCC56	4.1
Large intestine	HCT116	4.6
Large intestine	HCT15	4
Large intestine	HS675T	4.3
Large intestine	HS698T	4
Large intestine	HT115	4.1
Large intestine	HT29	4
Large intestine	HT55	4.2
Large intestine	KM12	4.4
Large intestine	LOVO	3.9
Large intestine	LS1034	3.9
Large intestine	LS123	3.9
Large intestine	LS180	3.9
Large intestine	LS411N	4.1
Large intestine	LS513	4.1
Large intestine	MDST8	4.1
Large intestine	NCIH508	4.2
Large intestine	NCIH716	3.8
Large intestine	NCIH747	4.3
Large intestine	OUMS23	4.3
Large intestine	RCM1	4
Large intestine	RKO	4.3
Large intestine	SKCO1	4.1
Large intestine	SNU1040	4.3
Large intestine	SNU1197	4
Large intestine	SNU175	4.4
Large intestine	SNU283	4
Large intestine	SNU407	4.9
Large intestine	SNU503	4.4
Large intestine	SNU61	4
Large intestine	SNU81	4.1
Large intestine	SNUC1	5
Large intestine	SNUC2A	5.5
Large intestine	SNUC4	4
Large intestine	SNUC5	4
Large intestine	SW1116	4
Large intestine	SW1417	3.9
Large intestine	SW1463	4.4
Large intestine	SW403	4.1
Large intestine	SW480	4.2
Large intestine	SW48	4
Large intestine	SW620	3.9
Large intestine	SW837	3.8
Large intestine	SW948	4.3
Large intestine	T84	3.9
Liver	ALEXANDERCELLS	4.2
Liver	C3A	4
Liver	HEP3B217	3.9
Liver	HEPG2	4.2
Liver	HLE	3.8
Liver	HLF	3.9
Liver	HUH1	4.1
Liver	HUH6	4.5
Liver	HUH7	3.9
Liver	JHH1	3.9
Liver	JHH2	4
Liver	JHH4	4
Liver	JHH5	5.4
Liver	JHH6	3.7
Liver	JHH7	4.5
Liver	LI7	4.3
Liver	PLCPRF5	4
Liver	SKHEP1	3.8
Liver	SNU182	4.3
Liver	SNU387	4.1
Liver	SNU398	4.2
Liver	SNU423	4
Liver	SNU449	4.3
Liver	SNU475	4
Liver	SNU761	3.9
Liver	SNU878	4.1
Liver	SNU886	4
Lung	A549	4.1
Lung	ABC1	4.5
Lung	BEN	3.9
Lung	CAL12T	4.5
Lung	CALU1	4.1
Lung	CALU3	4.2
Lung	CALU6	4.4
Lung	CHAGOK1	5.5
Lung	COLO668	3.6
Lung	COLO699	4.1
Lung	CORL105	3.8
Lung	CORL23	4.7
Lung	CORL24	4.8
Lung	CORL279	4.2
Lung	CORL311	4
Lung	CORL47	4.4
Lung	CORL51	4.3
Lung	CORL88	4.5
Lung	CORL95	4.3
Lung	CPCN	4.2
Lung	DMS114	5
Lung	DMS153	5.3
Lung	DMS273	4.2
Lung	DMS454	4.3
Lung	DMS53	6
Lung	DMS79	3.8
Lung	DV90	4.8
Lung	EBC1	4
Lung	EPLC272H	4.1
Lung	HARA	4.1
Lung	HCC1171	3.7
Lung	HCC1195	4.1
Lung	HCC15	4.1
Lung	HCC2279	4
Lung	HCC2935	4
Lung	HCC33	4.3
Lung	HCC366	4.4
Lung	HCC4006	3.9
Lung	HCC44	4.1
Lung	HCC78	4
Lung	HCC827	4
Lung	HCC95	3.9
Lung	HLC1	4
Lung	HLFA	3.8
Lung	HS229T	3.9
Lung	HS618T	4.2
Lung	IALM	4.2
Lung	KNS62	4.1
Lung	LC1F	4.9
Lung	LC1SQSF	5.8
Lung	LCLC103H	4
Lung	LCLC97TM1	4.2
Lung	LK2	4.6
Lung	LOUNH91	4.3
Lung	LU65	4.4
Lung	LU99	4.2
Lung	LUDLU1	4.1
Lung	LXF289	4
Lung	MORCPR	4.1
Lung	NCIH1048	4
Lung	NCIH1092	3.7
Lung	NCIH1105	6.8
Lung	NCIH1155	4
Lung	NCIH1184	4.2
Lung	NCIH1299	4.3
Lung	NCIH1339	4
Lung	NCIH1341	5.2
Lung	NCIH1355	5.2
Lung	NCIH1373	4.3
Lung	NCIH1385	4.3
Lung	NCIH1395	4.4
Lung	NCIH1435	3.9
Lung	NCIH1436	4.1
Lung	NCIH1437	4.3
Lung	NCIH146	4.2
Lung	NCIH1563	3.9
Lung	NCIH1568	4.8
Lung	NCIH1573	5.5
Lung	NCIH1581	4.5
Lung	NCIH1618	3.9
Lung	NCIH1623	5.9
Lung	NCIH1648	3.8
Lung	NCIH1650	4.1
Lung	NCIH1651	4
Lung	NCIH1666	4.5
Lung	NCIH1693	7.5
Lung	NCIH1694	4.3
Lung	NCIH1703	4.8
Lung	NCIH1734	4.8
Lung	NCIH1755	4.6
Lung	NCIH1781	4
Lung	NCIH1792	4.3
Lung	NCIH1793	3.9
Lung	NCIH1836	4
Lung	NCIH1838	3.9
Lung	NCIH1869	4
Lung	NCIH1876	3.9
Lung	NCIH1915	3.9
Lung	NCIH1930	6.2
Lung	NCIH1944	4.8
Lung	NCIH1963	4.2
Lung	NCIH196	4.1
Lung	NCIH1975	4.1
Lung	NCIH2009	4.5
Lung	NCIH2023	4.5
Lung	NCIH2029	4.8
Lung	NCIH2030	4
Lung	NCIH2066	4.1
Lung	NCIH2081	3.6
Lung	NCIH2085	4.7
Lung	NCIH2087	4.6
Lung	NCIH209	4.9
Lung	NCIH2106	5.1
Lung	NCIH2110	6.4
Lung	NCIH211	4.4
Lung	NCIH2122	5.1
Lung	NCIH2126	7.4
Lung	NCIH2141	3.9
Lung	NCIH2170	4.1
Lung	NCIH2171	4.5
Lung	NCIH2172	3.8
Lung	NCIH2196	4.3
Lung	NCIH2227	5.1
Lung	NCIH2228	3.6
Lung	NCIH226	4.2
Lung	NCIH2286	5.3
Lung	NCIH2291	5.9
Lung	NCIH2342	5.3
Lung	NCIH2347	5.7
Lung	NCIH23	4.7
Lung	NCIH2405	4
Lung	NCIH2444	4
Lung	NCIH292	3.6
Lung	NCIH322	5.1
Lung	NCIH3255	3.9
Lung	NCIH358	4
Lung	NCIH441	4.3
Lung	NCIH446	4.1
Lung	NCIH460	3.9
Lung	NCIH510	5.8
Lung	NCIH520	3.8
Lung	NCIH522	4.3
Lung	NCIH524	3.9
Lung	NCIH526	4.6
Lung	NCIH596	3.8
Lung	NCIH647	4.7
Lung	NCIH650	4.2
Lung	NCIH661	4
Lung	NCIH69	4.2
Lung	NCIH727	7.2
Lung	NCIH810	3.8
Lung	NCIH82	3.8
Lung	NCIH838	3.8
Lung	NCIH841	4.2
Lung	NCIH854	5.7
Lung	NCIH889	4.2
Lung	PC14	4
Lung	RERFLCAD1	5.5
Lung	RERFLCAD2	3.9
Lung	RERFLCAI	4.1
Lung	RERFLCKJ	3.9
Lung	RERFLCMS	4.1
Lung	RERFLCSQ1	4.1
Lung	SBC5	4.1
Lung	SCLC21H	4.2
Lung	SHP77	4.4
Lung	SKLU1	4
Lung	SKMES1	4.2
Lung	SQ1	4
Lung	SW1271	3.9
Lung	SW1573	4
Lung	SW900	4.2
Lung	VMRCLCD	4.1
Lung	VMRCLCP	4
Oesophagus	COLO680N	4
Oesophagus	ECGI10	4
Oesophagus	KYSE140	5.3
Oesophagus	KYSE150	4.2
Oesophagus	KYSE180	4.3
Oesophagus	KYSE270	3.9
Oesophagus	KYSE30	3.9
Oesophagus	KYSE410	5.2
Oesophagus	KYSE450	7
Oesophagus	KYSE510	4.5
Oesophagus	KYSE520	4.6
Oesophagus	KYSE70	3.9
Oesophagus	OE19	4.3
Oesophagus	OE33	3.9
Oesophagus	TE10	5
Oesophagus	TE11	6.4
Oesophagus	TE14	4.2
Oesophagus	TE15	7.5
Oesophagus	TE1	5.2
Oesophagus	TE4	7.6
Oesophagus	TE5	4.1
Oesophagus	TE6	4.2
Oesophagus	TE8	4.1
Oesophagus	TE9	7.3
Oesophagus	TT	4.6
Ovary	59M	4
Ovary	A2780	3.9
Ovary	CAOV3	4.6
Ovary	CAOV4	4.3
Ovary	COLO704	4
Ovary	COV318	4
Ovary	COV362	3.9
Ovary	COV434	4.1
Ovary	COV504	4
Ovary	COV644	4.3
Ovary	EFO21	4.2
Ovary	EFO27	3.8
Ovary	ES2	4.3
Ovary	FUOV1	3.9
Ovary	HEYA8	4.2
Ovary	HS571T	3.9
Ovary	IGROV1	4.2
Ovary	JHOC5	4.3
Ovary	JHOM1	4.1
Ovary	JHOM2B	4.2
Ovary	JHOS2	5.3
Ovary	JHOS4	4.5
Ovary	KURAMOCHI	3.5
Ovary	MCAS	4
Ovary	NIHOVCAR3	5.4
Ovary	OAW28	4
Ovary	OAW42	4.4
Ovary	OC314	4.3
Ovary	OC316	4
Ovary	ONCODG1	4.9
Ovary	OV56	4.9
Ovary	OV7	3.8
Ovary	OV90	5.1
Ovary	OVCAR4	3.9
Ovary	OVCAR8	4.3
Ovary	OVISE	4.1
Ovary	OVK18	4.6
Ovary	OVKATE	3.8
Ovary	OVMANA	4.1
Ovary	OVSAHO	4.1
Ovary	OVTOKO	3.8
Ovary	RMGI	4.1
Ovary	RMUGS	4.5
Ovary	SKOV3	4.4
Ovary	SNU119	4.1
Ovary	SNU840	4
Ovary	SNU8	3.8
Ovary	TOV112D	4.1
Ovary	TOV21G	4.2
Ovary	TYKNU	4.3
Pancreas	ASPC1	4.1
Pancreas	BXPC3	4.2
Pancreas	CAPAN1	4
Pancreas	CAPAN2	4.9
Pancreas	CFPAC1	4.2
Pancreas	DANG	4
Pancreas	HPAC	5.2
Pancreas	HPAFII	4.5
Pancreas	HS766T	3.9
Pancreas	HUPT3	3.9
Pancreas	HUPT4	4.1
Pancreas	KCIMOH1	5.4
Pancreas	KLM1	5.5
Pancreas	KP2	3.9
Pancreas	KP3	4.3
Pancreas	KP4	4.8
Pancreas	L33	6.3
Pancreas	MIAPACA2	4.5
Pancreas	PANC0203	3.9
Pancreas	PANC0213	4.2
Pancreas	PANC0327	3.9
Pancreas	PANC0403	4.2
Pancreas	PANC0504	3.7
Pancreas	PANC0813	4.3
Pancreas	PANC1005	4.2
Pancreas	PANC1	4.5
Pancreas	PATU8902	5.5
Pancreas	PATU8988S	3.9
Pancreas	PATU8988T	4.4
Pancreas	PK1	4.3
Pancreas	PK45H	3.8
Pancreas	PK59	3.9
Pancreas	PL45	4.3
Pancreas	PSN1	3.8
Pancreas	QGP1	4
Pancreas	SNU213	3.8
Pancreas	SNU324	3.8
Pancreas	SNU410	4.3
Pancreas	SU8686	5.5
Pancreas	SUIT2	4
Pancreas	SW1990	4.1
Pancreas	T3M4	6.4
Pancreas	TCCPAN2	4.1
Pancreas	YAPC	3.8
Pleura	ACCMESO1	4.3
Pleura	DM3	3.9
Pleura	ISTMES1	4.2
Pleura	ISTMES2	4.6
Pleura	JL1	3.9
Pleura	MPP89	4.2
Pleura	MSTO211H	4
Pleura	NCIH2052	4.1
Pleura	NCIH2452	4.1
Pleura	NCIH28	4
Prostate	22RV1	4.1
Prostate	DU145	4.5
Prostate	LNCAPCLONEFGC	3.8
Prostate	MDAPCA2B	4.2
Prostate	NCIH660	3.8
Prostate	PC3	4.3
Prostate	VCAP	4.7
Salivary gland	A253	4.2
Salivary gland	YD15	6.7
Skin	A101D	4
Skin	A2058	3.8
Skin	A375	4.2
Skin	C32	4.5
Skin	CHL1	4.1
Skin	CJM	4.2
Skin	COLO679	4.2
Skin	COLO741	4
Skin	COLO783	4.1
Skin	COLO792	4
Skin	COLO800	4.2
Skin	COLO818	3.8
Skin	COLO829	4.2
Skin	COLO849	4
Skin	G361	4.2
Skin	GRM	4
Skin	HMCB	3.8
Skin	HS294T	4.4
Skin	HS600T	4.2
Skin	HS688AT	4.4
Skin	HS695T	4.5
Skin	HS839T	3.8
Skin	HS852T	4.2
Skin	HS895T	4.5
Skin	HS934T	3.9
Skin	HS936T	3.9
Skin	HS939T	3.8
Skin	HS940T	4.1
Skin	HS944T	4.8
Skin	HT144	4
Skin	IGR1	4.1
Skin	IGR37	4
Skin	IGR39	4.2
Skin	IPC298	4.2
Skin	K029AX	3.9
Skin	LOXIMVI	4
Skin	MALME3M	4
Skin	MDAMB435S	3.9
Skin	MELHO	4.3
Skin	MELJUSO	4.3
Skin	MEWO	4
Skin	RPMI7951	3.7
Skin	RVH421	4
Skin	SH4	4.1
Skin	SKMEL1	4.3
Skin	SKMEL24	3.8
Skin	SKMEL28	3.8
Skin	SKMEL2	4.1
Skin	SKMEL30	4.4
Skin	SKMEL31	4
Skin	SKMEL3	3.8
Skin	SKMEL5	3.9
Skin	UACC257	4.3
Skin	UACC62	3.8
Skin	WM115	3.9
Skin	WM1799	4
Skin	WM2664	4
Skin	WM793	4.1
Skin	WM88	4.4
Skin	WM983B	4
Small intestine	HUTU80	4.4
Soft tissue	A204	4
Soft tissue	G401	4.2
Soft tissue	G402	4.2
Soft tissue	GCT	3.8
Soft tissue	HS729	4.3
Soft tissue	HT1080	4.2
Soft tissue	KYM1	3.9
Soft tissue	MESSA	4.5
Soft tissue	RD	3.8
Soft tissue	RH30	3.7
Soft tissue	RH41	4
Soft tissue	RKN	4.4
Soft tissue	S117	4.5
Soft tissue	SJRH30	4.3
Soft tissue	SKLMS1	4.1
Soft tissue	SKUT1	4.1
Soft tissue	TE125T	4
Soft tissue	TE159T	3.9
Soft tissue	TE441T	3.8
Soft tissue	TE617T	4.2
Stomach	2313287	4.5
Stomach	AGS	4.3
Stomach	AZ521	4
Stomach	ECC10	4.1
Stomach	ECC12	4.3
Stomach	FU97	4.1
Stomach	GCIY	3.9
Stomach	GSS	4
Stomach	GSU	4.2
Stomach	HGC27	3.9
Stomach	HS746T	4.2
Stomach	HUG1N	3.9
Stomach	IM95	5.2
Stomach	KATOIII	4.3
Stomach	KE39	4.3
Stomach	LMSU	4.1
Stomach	MKN1	4.2
Stomach	MKN45	4
Stomach	MKN74	4
Stomach	MKN7	4.1
Stomach	NCCSTCK140	4.3
Stomach	NCIN87	4.2
Stomach	NUGC2	4
Stomach	NUGC3	4.2
Stomach	NUGC4	4.5
Stomach	OCUM1	4.5
Stomach	RERFGC1B	4.6
Stomach	SH10TC	4.2
Stomach	SNU16	4
Stomach	SNU1	4.1
Stomach	SNU216	4.3
Stomach	SNU520	4.4
Stomach	SNU5	4
Stomach	SNU601	3.9
Stomach	SNU620	4.2
Stomach	SNU668	3.9
Stomach	SNU719	5.6
Stomach	TGBC11TKB	4.7
Thyroid	8305C	3.9
Thyroid	8505C	4.4
Thyroid	BCPAP	4
Thyroid	BHT101	4
Thyroid	CAL62	5.7
Thyroid	CGTHW1	3.8
Thyroid	FTC133	4.2
Thyroid	FTC238	3.8
Thyroid	ML1	3.9
Thyroid	SW579	4
Thyroid	TT2609C02	4
Thyroid	TT	4.9
Upper aerodigestive tract	BHY	4.4
Upper aerodigestive tract	BICR16	4.3
Upper aerodigestive tract	BICR18	4.2
Upper aerodigestive tract	BICR22	7.3
Upper aerodigestive tract	BICR31	7
Upper aerodigestive tract	BICR56	4.2
Upper aerodigestive tract	BICR6	4.9
Upper aerodigestive tract	CAL27	4
Upper aerodigestive tract	CAL33	3.8
Upper aerodigestive tract	DETROIT562	4
Upper aerodigestive tract	FADU	7.3
Upper aerodigestive tract	HS840T	4.2
Upper aerodigestive tract	HSC2	4.1
Upper aerodigestive tract	HSC3	4.2
Upper aerodigestive tract	HSC4	3.9
Upper aerodigestive tract	PECAPJ15	4.2
Upper aerodigestive tract	PECAPJ34CLONEC12	4
Upper aerodigestive tract	PECAPJ41CLONED2	3.9
Upper aerodigestive tract	PECAPJ49	3.9
Upper aerodigestive tract	SCC15	4
Upper aerodigestive tract	SCC25	4.2
Upper aerodigestive tract	SCC4	4.1
Upper aerodigestive tract	SCC9	4.1
Upper aerodigestive tract	SNU1076	4.5
Upper aerodigestive tract	SNU1214	3.8
Upper aerodigestive tract	SNU46	4.5
Upper aerodigestive tract	SNU899	3.9
Upper aerodigestive tract	YD10B	4
Upper aerodigestive tract	YD38	6.4
Upper aerodigestive tract	YD8	4.1
Urinary tract	5637	4
Urinary tract	639V	4.1
Urinary tract	647V	3.8
Urinary tract	BC3C	4.7
Urinary tract	BFTC905	7.1
Urinary tract	CAL29	3.8
Urinary tract	HS172T	3.8
Urinary tract	HT1197	4
Urinary tract	HT1376	3.9
Urinary tract	J82	4.1
Urinary tract	JMSU1	4.7
Urinary tract	KMBC2	3.8
Urinary tract	KU1919	4.1
Urinary tract	RT11284	4.2
Urinary tract	RT112	4.1
Urinary tract	RT4	4.2
Urinary tract	SCABER	4.2
Urinary tract	SW1710	3.7
Urinary tract	SW780	4.9
Urinary tract	T24	3.8
Urinary tract	TCCSUP	4
Urinary tract	UMUC1	3.8
Urinary tract	UMUC3	4
Urinary tract	VMCUB1	3.9

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	0
Adrenal gland	0
Appendix	0.1
Bone marrow	0.2
Breast	4.5
Cerebral cortex	0.5
Cervix, uterine	0.1
Colon	0.6
Duodenum	0.5
Endometrium	0
Epididymis	7.8
Esophagus	0.6
Fallopian tube	1.4
Gallbladder	0.4
Heart muscle	0
Kidney	1.1
Liver	0
Lung	0.1
Lymph node	0
Ovary	0
Pancreas	0
Parathyroid gland	0.3
Placenta	0.3
Prostate	1.2
Rectum	0.8
Salivary gland	0.3
Seminal vesicle	0.5
Skeletal muscle	0
Skin	0.2
Small intestine	0.5
Smooth muscle	0
Spleen	0
Stomach	0.4
Testis	42.4
Thyroid gland	1.1
Tonsil	0.4
Urinary bladder	0.1

> Text Mining based Expression [ TOP ]
There is no record.

Summary
Symbol	TDRD5
Name	tudor domain containing 5
Aliases	FLJ34823; TUDOR3; Tudor domain-containing protein 5
Location	1q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.181	0.000251	7.2	51	41.8	Gain
BRCA	Breast invasive carcinoma	1075	0.216	8.62e-13	2.3	24.1	73.6	Gain
CESC	Cervical and endocervical cancers	292	0.145	0.0134	3.1	44.9	52.1	Gain
COAD	Colon adenocarcinoma	449	0.088	0.0615	9.4	69.3	21.4	Neutral
ESCA	Esophageal carcinoma	183	0.16	0.031	9.3	44.3	46.4	Gain
HNSC	Head and Neck squamous cell carcinoma	514	0.229	1.49e-07	7	67.1	25.9	Neutral
KIRC	Kidney renal clear cell carcinoma	525	0.011	0.804	6.3	82.3	11.4	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	0.277	1.74e-06	7.3	86.5	6.2	Neutral
LGG	Brain Lower Grade Glioma	513	-0.012	0.779	2.5	91.4	6	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.036	0.489	1.6	26.6	71.7	Gain
LUAD	Lung adenocarcinoma	512	0.068	0.124	2.5	27.1	70.3	Gain
LUSC	Lung squamous cell carcinoma	498	0.228	2.56e-07	5.4	43.6	51	Gain
OV	Ovarian serous cystadenocarcinoma	300	0.279	8.99e-07	4.3	40.3	55.3	Gain
PAAD	Pancreatic adenocarcinoma	177	0.318	1.65e-05	4	64.4	31.6	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	-0.106	0.181	8.6	76.5	14.8	Neutral
PRAD	Prostate adenocarcinoma	491	0.013	0.777	2.4	91.9	5.7	Neutral
READ	Rectum adenocarcinoma	164	0.034	0.668	9.1	60.4	30.5	Neutral
SARC	Sarcoma	255	0.151	0.016	14.9	55.7	29.4	Neutral
SKCM	Skin Cutaneous Melanoma	367	0.164	0.00166	6	40.3	53.7	Gain
STAD	Stomach adenocarcinoma	413	0.295	9.36e-10	4.1	62.7	33.2	Neutral
TGCT	Testicular Germ Cell Tumors	150	-0.057	0.487	0.7	52.7	46.7	Gain
THCA	Thyroid carcinoma	497	-0.008	0.858	0.6	94	5.4	Neutral
THYM	Thymoma	119	0.292	0.00126	0	79	21	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.294	3.52e-12	1.5	55.3	43.2	Gain

Summary
Symbol	TDRD5
Name	tudor domain containing 5
Aliases	FLJ34823; TUDOR3; Tudor domain-containing protein 5
Location	1q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

[ TOP ]

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.42	0	17	408	-0.05	0.117	NS/NA
BRCA	Breast invasive carcinoma	-0.368	0	83	785	0.001	0.161	NS/NA
CESC	Cervical and endocervical cancers	-0.597	0	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.358	7.46e-11	19	297	-0.027	0.475	NS/NA
ESCA	Esophageal carcinoma	-0.342	1.21e-06	9	185	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.321	2.31e-14	20	522	0.205	3.51e-05	Increased
KIRC	Kidney renal clear cell carcinoma	-0.15	0.00555	24	319	0.155	1.07e-28	NS/NA
KIRP	Kidney renal papillary cell carcinoma	-0.364	1.28e-10	23	275	0.004	1.82e-11	NS/NA
LGG	Brain Lower Grade Glioma	-0.05	0.252	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.187	0.000133	41	373	0.351	2.59e-58	Increased
LUAD	Lung adenocarcinoma	-0.511	0	21	456	0.046	5.09e-07	NS/NA
LUSC	Lung squamous cell carcinoma	-0.432	0	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	-0.783	0.0172	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.377	1.81e-07	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.338	2.63e-06	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.571	0	35	498	0.086	1.22e-08	NS/NA
READ	Rectum adenocarcinoma	-0.325	0.000971	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.179	0.00371	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.229	5.13e-07	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.511	0	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.68	0	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.307	1.44e-13	50	509	-0.042	0.00253	NS/NA
THYM	Thymoma	-0.477	4.13e-08	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.18	1e-04	34	431	-0.05	0.0589	NS/NA

Summary
Symbol	TDRD5
Name	tudor domain containing 5
Aliases	FLJ34823; TUDOR3; Tudor domain-containing protein 5
Location	1q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Level	Level Name
Adrenal gland	0	Not detected
Appendix	0	Not detected
Bone marrow	0	Not detected
Breast	0	Not detected
Bronchus	0	Not detected
Caudate	0	Not detected
Cerebellum	0	Not detected
Cerebral cortex	0	Not detected
Cervix, uterine	0	Not detected
Colon	0	Not detected
Duodenum	0	Not detected
Endometrium	0	Not detected
Epididymis	0	Not detected
Esophagus	0	Not detected
Fallopian tube	0	Not detected
Gallbladder	0	Not detected
Heart muscle	0	Not detected
Hippocampus	0	Not detected
Kidney	0	Not detected
Liver	0	Not detected
Lung	0	Not detected
Lymph node	0	Not detected
Oral mucosa	0	Not detected
Ovary	0	Not detected
Pancreas	0	Not detected
Parathyroid gland	0	Not detected
Placenta	0	Not detected
Prostate	0	Not detected
Rectum	0	Not detected
Salivary gland	0	Not detected
Seminal vesicle	0	Not detected
Skeletal muscle	0	Not detected
Skin	0	Not detected
Small intestine	0	Not detected
Smooth muscle	0	Not detected
Soft tissue	0	Not detected
Spleen	0	Not detected
Stomach	0	Not detected
Testis	3	High
Thyroid gland	0	Not detected
Tonsil	0	Not detected
Urinary bladder	0	Not detected
Vagina	0	Not detected

Summary
Symbol	TDRD5
Name	tudor domain containing 5
Aliases	FLJ34823; TUDOR3; Tudor domain-containing protein 5
Location	1q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.444	NS	24476821
BRCA	Breast invasive carcinoma	521	0.0725	NS	23000897
COAD	Colon adenocarcinoma	149	0.0104	Significant	22810696
HNSC	Head and Neck squamous cell carcinoma	279	5.23e-10	Significant	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.143	NS	26536169
LGG	Brain Lower Grade Glioma	513	4.68e-05	Significant	26824661
LUAD	Lung adenocarcinoma	230	3.28e-06	Significant	25079552
LUSC	Lung squamous cell carcinoma	178	0.00227	Significant	22960745
OV	Ovarian serous cystadenocarcinoma	287	5.62e-07	Significant	21720365
PRAD	Prostate adenocarcinoma	333	0.142	NS	26544944
READ	Rectum adenocarcinoma	67	0.506	NS	22810696
SKCM	Skin Cutaneous Melanoma	315	0.205	NS	26091043
STAD	Stomach adenocarcinoma	277	3.19e-11	Significant	25079317
THCA	Thyroid carcinoma	391	0.927	NS	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	3.46e-05	Significant	23636398

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	0.996	0.985	NS
BRCA	Breast invasive carcinoma	1079	0.901	0.638	NS
CESC	Cervical and endocervical cancers	291	1.328	0.406	NS
COAD	Colon adenocarcinoma	439	1.289	0.393	NS
ESCA	Esophageal carcinoma	184	0.707	0.314	NS
HNSC	Head and Neck squamous cell carcinoma	518	1.33	0.129	NS
KIRC	Kidney renal clear cell carcinoma	531	1.051	0.814	NS
KIRP	Kidney renal papillary cell carcinoma	287	0.775	0.542	NS
LGG	Brain Lower Grade Glioma	511	0.661	0.113	NS
LIHC	Liver hepatocellular carcinoma	365	1.554	0.0677	NS
LUAD	Lung adenocarcinoma	502	0.919	0.69	NS
LUSC	Lung squamous cell carcinoma	494	0.993	0.97	NS
OV	Ovarian serous cystadenocarcinoma	303	0.688	0.0801	NS
PAAD	Pancreatic adenocarcinoma	177	0.712	0.272	NS
PCPG	Pheochromocytoma and Paraganglioma	179	0.674	0.752	NS
PRAD	Prostate adenocarcinoma	497	1.706	0.555	NS
READ	Rectum adenocarcinoma	159	0.62	0.353	NS
SARC	Sarcoma	259	0.965	0.896	NS
SKCM	Skin Cutaneous Melanoma	459	1.012	0.945	NS
STAD	Stomach adenocarcinoma	388	1.255	0.338	NS
TGCT	Testicular Germ Cell Tumors	134	0	0.119	NS
THCA	Thyroid carcinoma	500	2.571	0.231	NS
THYM	Thymoma	119	1.035	0.981	NS
UCEC	Uterine Corpus Endometrial Carcinoma	543	2.566	0.0035	Shorter

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	0.044	0.371	NS
BRCA	Breast invasive carcinoma	1071	-0.112	0.00025	Lower
CESC	Cervical and endocervical cancers	167	0.012	0.877	NS
COAD	Colon adenocarcinoma	445	-0.07	0.141	NS
ESCA	Esophageal carcinoma	162	0.07	0.375	NS
HNSC	Head and Neck squamous cell carcinoma	448	0.126	0.00778	Higher
KIRC	Kidney renal clear cell carcinoma	531	0.137	0.0016	Higher
KIRP	Kidney renal papillary cell carcinoma	260	-0.038	0.54	NS
LIHC	Liver hepatocellular carcinoma	347	0.057	0.289	NS
LUAD	Lung adenocarcinoma	507	0.013	0.775	NS
LUSC	Lung squamous cell carcinoma	497	0.066	0.144	NS
OV	Ovarian serous cystadenocarcinoma	302	-0.077	0.184	NS
PAAD	Pancreatic adenocarcinoma	176	0.072	0.343	NS
READ	Rectum adenocarcinoma	156	0.035	0.668	NS
SKCM	Skin Cutaneous Melanoma	410	-0.006	0.911	NS
STAD	Stomach adenocarcinoma	392	-0.069	0.174	NS
TGCT	Testicular Germ Cell Tumors	81	-0.331	0.00251	Lower
THCA	Thyroid carcinoma	499	-0.003	0.949	NS
UCEC	Uterine Corpus Endometrial Carcinoma	501	0.154	0.000549	Higher

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	-0.056	0.359	NS
HNSC	Head and Neck squamous cell carcinoma	498	0.16	0.000341	Higher
KIRC	Kidney renal clear cell carcinoma	525	0.179	3.58e-05	Higher
LGG	Brain Lower Grade Glioma	514	-0.162	0.000227	Lower
LIHC	Liver hepatocellular carcinoma	366	0.082	0.117	NS
OV	Ovarian serous cystadenocarcinoma	296	-0.022	0.711	NS
PAAD	Pancreatic adenocarcinoma	176	-0.021	0.787	NS
STAD	Stomach adenocarcinoma	406	-0.207	2.66e-05	Lower
UCEC	Uterine Corpus Endometrial Carcinoma	534	0.217	4.28e-07	Higher

Summary
Symbol	TDRD5
Name	tudor domain containing 5
Aliases	FLJ34823; TUDOR3; Tudor domain-containing protein 5
Location	1q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	TDRD5
Name	tudor domain containing 5
Aliases	FLJ34823; TUDOR3; Tudor domain-containing protein 5
Location	1q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for TDRD5.

Summary
Symbol	TDRD5
Name	tudor domain containing 5
Aliases	FLJ34823; TUDOR3; Tudor domain-containing protein 5
Location	1q25.2
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining [ TOP ]
There is no record for TDRD5.