Summary | |
---|---|
Symbol | UBR7 |
Name | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
Aliases | C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7 |
Location | 14q32.12 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway |
Domain |
PF02207 Putative zinc finger in N-recognin (UBR box) |
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Function |
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. |
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Classification |
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Biological Process | - |
Molecular Function |
GO:0016874 ligase activity |
Cellular Component | - |
KEGG | - |
Reactome | - |
Summary | |
---|---|
Symbol | UBR7 |
Name | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
Aliases | C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7 |
Location | 14q32.12 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining |
There is no record. |
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There is no record for UBR7. |
Summary | |
---|---|
Symbol | UBR7 |
Name | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
Aliases | C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7 |
Location | 14q32.12 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Post-translational modification (PTM) |
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Summary | |
---|---|
Symbol | UBR7 |
Name | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
Aliases | C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7 |
Location | 14q32.12 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change |
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There is no record. |
Summary | |
---|---|
Symbol | UBR7 |
Name | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
Aliases | C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7 |
Location | 14q32.12 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Somatic copy number alteration in primary tomur tissue |
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Summary | |
---|---|
Symbol | UBR7 |
Name | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
Aliases | C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7 |
Location | 14q32.12 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Methylation level in the promoter region of CR |
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Summary | |
---|---|
Symbol | UBR7 |
Name | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
Aliases | C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7 |
Location | 14q32.12 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Primary tumor tissue from TCGA > Normal tumor tissue from HPA |
There is no record. |
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Summary | |
---|---|
Symbol | UBR7 |
Name | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
Aliases | C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7 |
Location | 14q32.12 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade |
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Showing 1 to 9 of 9 rows |
Summary | |
---|---|
Symbol | UBR7 |
Name | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
Aliases | C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7 |
Location | 14q32.12 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data |
Summary | |
---|---|
Symbol | UBR7 |
Name | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
Aliases | C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7 |
Location | 14q32.12 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Drugs from DrugBank database |
There is no record for UBR7. |
Summary | |
---|---|
Symbol | UBR7 |
Name | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
Aliases | C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7 |
Location | 14q32.12 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Cancer Gene Databases | ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes) |
Content |
> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining |
There is no record for UBR7. |