CR2Cancer

Summary
Symbol	UBR7
Name	ubiquitin protein ligase E3 component n-recognin 7 (putative)
Aliases	C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7
Location	14q32.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

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Domain

PF02207 Putative zinc finger in N-recognin (UBR box)

Function

E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

Classification

Class	Modification	Substrate	Product	PubMed
DNA modification cofactor	DNA methylation	#	#	21745816

> Gene Ontology [ TOP ]
Biological Process	-
Molecular Function	GO:0016874 ligase activity
Cellular Component	-

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	-

Summary
Symbol	UBR7
Name	ubiquitin protein ligase E3 component n-recognin 7 (putative)
Aliases	C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7
Location	14q32.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM958930	c.379A>G	p.N127D	Substitution - Missense	Endometrium
COSM4738967	c.960+1G>A	p.?	Unknown	Large_intestine
COSM5905972	c.805C>T	p.L269F	Substitution - Missense	Skin
COSM699054	c.162G>A	p.K54K	Substitution - coding silent	Lung
COSM2252223	c.292C>T	p.R98C	Substitution - Missense	Breast
COSM3499056	c.918C>G	p.P306P	Substitution - coding silent	Skin
COSM958938	c.1047G>T	p.Q349H	Substitution - Missense	Endometrium
COSM2252223	c.292C>T	p.R98C	Substitution - Missense	Skin
COSM958931	c.473G>A	p.C158Y	Substitution - Missense	Endometrium
COSM1749023	c.788C>G	p.S263C	Substitution - Missense	Urinary_tract
COSM958934	c.675A>G	p.K225K	Substitution - coding silent	Endometrium
COSM1563044	c.424C>G	p.P142A	Substitution - Missense	Large_intestine
COSM5727286	c.919C>T	p.L307L	Substitution - coding silent	Skin
COSM699053	c.340C>T	p.L114F	Substitution - Missense	Lung
COSM267719	c.838G>A	p.A280T	Substitution - Missense	Large_intestine
COSM5101037	c.30G>A	p.R10R	Substitution - coding silent	Large_intestine
COSM3744483	c.745C>T	p.R249W	Substitution - Missense	Liver
COSM2252223	c.292C>T	p.R98C	Substitution - Missense	Skin
COSM5043184	c.853G>T	p.G285C	Substitution - Missense	Liver
COSM3420106	c.608A>G	p.K203R	Substitution - Missense	Large_intestine
COSM4578070	c.466G>A	p.V156I	Substitution - Missense	Upper_aerodigestive_tract
COSM5470314	c.503G>A	p.G168D	Substitution - Missense	Large_intestine
COSM433506	c.999T>C	p.D333D	Substitution - coding silent	Breast
COSM1188897	c.13G>T	p.E5*	Substitution - Nonsense	Lung
COSM3754179	c.19G>A	p.A7T	Substitution - Missense	Large_intestine
COSM1269669	c.35delC	p.S12fs*42	Deletion - Frameshift	Stomach
COSM4793000	c.151G>T	p.G51C	Substitution - Missense	Liver
COSM4053102	c.1006G>A	p.D336N	Substitution - Missense	Stomach
COSM2252223	c.292C>T	p.R98C	Substitution - Missense	Skin
COSM5806446	c.777A>G	p.P259P	Substitution - coding silent	Liver
COSM4053101	c.942T>C	p.C314C	Substitution - coding silent	Stomach
COSM5462420	c.967T>C	p.Y323H	Substitution - Missense	Large_intestine
COSM699051	c.686G>T	p.G229V	Substitution - Missense	Lung
COSM1749024	c.952G>A	p.D318N	Substitution - Missense	Urinary_tract
COSM699049	c.1006G>T	p.D336Y	Substitution - Missense	Lung
COSM699050	c.783C>T	p.A261A	Substitution - coding silent	Lung
COSM4578070	c.466G>A	p.V156I	Substitution - Missense	Bone
COSM214069	c.285-1G>C	p.?	Unknown	Breast
COSM1749023	c.788C>G	p.S263C	Substitution - Missense	Urinary_tract
COSM1707741	c.230C>T	p.A77V	Substitution - Missense	Skin
COSM958935	c.900C>G	p.D300E	Substitution - Missense	Endometrium
COSM5015260	c.875A>G	p.K292R	Substitution - Missense	Kidney
COSM5614181	c.484T>G	p.F162V	Substitution - Missense	Lung
COSM3420105	c.244T>G	p.C82G	Substitution - Missense	Large_intestine
COSM1371642	c.470T>A	p.V157D	Substitution - Missense	Large_intestine
COSM1470749	c.690G>A	p.E230E	Substitution - coding silent	Prostate
COSM5692551	c.1009A>T	p.T337S	Substitution - Missense	Soft_tissue
COSM3499055	c.708C>T	p.L236L	Substitution - coding silent	Skin
COSM433505	c.990delC	p.L331fs*1	Deletion - Frameshift	Breast
COSM1323326	c.564_594del31	p.C189fs*3	Deletion - Frameshift	Ovary
COSM4053102	c.1006G>A	p.D336N	Substitution - Missense	Large_intestine
COSM4793000	c.151G>T	p.G51C	Substitution - Missense	Liver
COSM5624280	c.466G>T	p.V156L	Substitution - Missense	Oesophagus
COSM324167	c.1069C>G	p.L357V	Substitution - Missense	Lung
COSM2252223	c.292C>T	p.R98C	Substitution - Missense	Skin
COSM4779904	c.1058G>A	p.R353K	Substitution - Missense	Liver
COSM3361280	c.352G>A	p.A118T	Substitution - Missense	Kidney
COSM958933	c.638G>A	p.R213Q	Substitution - Missense	Endometrium
COSM699052	c.345+1G>C	p.?	Unknown	Lung
COSM958933	c.638G>A	p.R213Q	Substitution - Missense	Large_intestine
COSM2252223	c.292C>T	p.R98C	Substitution - Missense	Skin
COSM958932	c.602-1G>A	p.?	Unknown	Endometrium
COSM1231637	c.268G>T	p.E90*	Substitution - Nonsense	Large_intestine
COSM1749024	c.952G>A	p.D318N	Substitution - Missense	Urinary_tract
COSM958936	c.1012G>A	p.V338I	Substitution - Missense	Endometrium
COSM958937	c.1024G>T	p.E342*	Substitution - Nonsense	Endometrium
COSM2252223	c.292C>T	p.R98C	Substitution - Missense	Skin
COSM5882538	c.961-1G>A	p.?	Unknown	Large_intestine
COSM699048	c.1116C>G	p.L372L	Substitution - coding silent	Lung
COSM4497546	c.499C>T	p.L167F	Substitution - Missense	Skin
COSM5681638	c.1199A>G	p.E400G	Substitution - Missense	Soft_tissue
COSM4578070	c.466G>A	p.V156I	Substitution - Missense	Upper_aerodigestive_tract
COSM416564	c.1278G>C	p.*426Y	Nonstop extension	Urinary_tract
COSM296643	c.1161C>T	p.L387L	Substitution - coding silent	Large_intestine
COSM5165290	c.960+4_960+7delAAGT	p.?	Unknown	Large_intestine
COSM1563043	c.465C>T	p.C155C	Substitution - coding silent	Large_intestine
COSM2252223	c.292C>T	p.R98C	Substitution - Missense	Skin
COSM5184924	c.438C>T	p.D146D	Substitution - coding silent	Large_intestine
COSM958929	c.151-2A>G	p.?	Unknown	Endometrium

> Text Mining based Variations [ TOP ]
There is no record for UBR7.

Summary
Symbol	UBR7
Name	ubiquitin protein ligase E3 component n-recognin 7 (putative)
Aliases	C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7
Location	14q32.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

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Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant
Q8N806	354	S	Phosphoserine	-	No	None detected

Summary
Symbol	UBR7
Name	ubiquitin protein ligase E3 component n-recognin 7 (putative)
Aliases	C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7
Location	14q32.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

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Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	5.452	5.363	-0.091	0.578	NS
BRCA	Breast invasive carcinoma	112	1100	5.868	6.163	0.307	4.63e-08	NS
CESC	Cervical and endocervical cancers	3	306	5.539	6.065	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	5.775	5.436	-0.412	2.77e-08	NS
ESCA	Esophageal carcinoma	11	185	5.582	5.466	-0.114	0.582	NS
GBM	Glioblastoma multiforme	5	166	6.24	6.483	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	5.341	5.441	0.134	0.0757	NS
KIRC	Kidney renal clear cell carcinoma	72	534	5.769	5.995	0.117	0.0254	NS
KIRP	Kidney renal papillary cell carcinoma	32	291	5.578	5.757	0.124	0.142	NS
LAML	Acute Myeloid Leukemia	0	173	NA	6.122	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	6.213	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	4.538	4.511	-0.023	0.773	NS
LUAD	Lung adenocarcinoma	59	517	5.345	5.381	0.02	0.767	NS
LUSC	Lung squamous cell carcinoma	51	501	5.33	5.644	0.316	2.09e-05	NS
OV	Ovarian serous cystadenocarcinoma	0	307	NA	5.482	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	5.429	5.3	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	5.148	5.548	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	5.641	5.599	-0.03	0.574	NS
READ	Rectum adenocarcinoma	10	167	5.807	5.306	-0.556	0.000208	NS
SARC	Sarcoma	2	263	5.341	5.843	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	5.796	5.704	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	5.437	5.381	-0.025	0.783	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	5.479	NA	NA	NA
THCA	Thyroid carcinoma	59	509	5.618	5.49	-0.103	0.00203	NS
THYM	Thymoma	2	120	6.165	6.157	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	5.518	5.325	-0.141	0.13	NS

> Cancer Cell Line Encyclopedia (CCLE)

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Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	10.3
Autonomic ganglia	CHP212	9.7
Autonomic ganglia	IMR32	10.3
Autonomic ganglia	KELLY	9.8
Autonomic ganglia	KPNRTBM1	10.3
Autonomic ganglia	KPNSI9S	9.2
Autonomic ganglia	KPNYN	10.3
Autonomic ganglia	MHHNB11	8.3
Autonomic ganglia	NB1	9.6
Autonomic ganglia	NH6	9.9
Autonomic ganglia	SHSY5Y	9.5
Autonomic ganglia	SIMA	10
Autonomic ganglia	SKNAS	9.6
Autonomic ganglia	SKNBE2	9.9
Autonomic ganglia	SKNDZ	9.6
Autonomic ganglia	SKNFI	10.2
Autonomic ganglia	SKNSH	9.8
Biliary tract	HUCCT1	9.8
Biliary tract	HUH28	8.7
Biliary tract	SNU1079	9.6
Biliary tract	SNU1196	10.4
Biliary tract	SNU245	9.7
Biliary tract	SNU308	9.7
Biliary tract	SNU478	9.2
Bone	143B	10.3
Bone	A673	10.7
Bone	CADOES1	9.7
Bone	CAL78	10.9
Bone	G292CLONEA141B1	9.6
Bone	HOS	9.7
Bone	HS706T	9
Bone	HS737T	8.6
Bone	HS819T	8.3
Bone	HS821T	9.1
Bone	HS822T	8.5
Bone	HS863T	9.3
Bone	HS870T	9
Bone	HS888T	9.5
Bone	MG63	9.4
Bone	MHHES1	9.5
Bone	OUMS27	9.3
Bone	RDES	9.4
Bone	SJSA1	9.4
Bone	SKES1	10.6
Bone	SKNMC	10.8
Bone	SW1353	8.9
Bone	T173	9.1
Bone	TC71	10
Bone	U2OS	9.1
Breast	AU565	9.7
Breast	BT20	9.2
Breast	BT474	10
Breast	BT483	9
Breast	BT549	9.4
Breast	CAL120	8.8
Breast	CAL148	10.6
Breast	CAL51	10.1
Breast	CAL851	8.8
Breast	CAMA1	9.8
Breast	DU4475	10.1
Breast	EFM192A	10.8
Breast	EFM19	9.6
Breast	EVSAT	10
Breast	HCC1143	9.4
Breast	HCC1187	9.6
Breast	HCC1395	10.4
Breast	HCC1419	9.9
Breast	HCC1428	11
Breast	HCC1500	10.1
Breast	HCC1569	8.6
Breast	HCC1599	8.6
Breast	HCC1806	8.6
Breast	HCC1937	9.6
Breast	HCC1954	9.5
Breast	HCC202	10.2
Breast	HCC2157	8.7
Breast	HCC2218	10.2
Breast	HCC38	9.4
Breast	HCC70	9.5
Breast	HDQP1	8.6
Breast	HMC18	8.8
Breast	HS274T	9.4
Breast	HS281T	9.2
Breast	HS343T	9.4
Breast	HS578T	7.7
Breast	HS606T	8.6
Breast	HS739T	8.5
Breast	HS742T	8.2
Breast	JIMT1	8.6
Breast	KPL1	10.5
Breast	MCF7	10
Breast	MDAMB134VI	10.2
Breast	MDAMB157	9.9
Breast	MDAMB175VII	9.7
Breast	MDAMB231	10.1
Breast	MDAMB361	9.7
Breast	MDAMB415	9.5
Breast	MDAMB436	9.8
Breast	MDAMB453	10.7
Breast	MDAMB468	8.8
Breast	SKBR3	9.7
Breast	T47D	10.1
Breast	UACC812	9.3
Breast	UACC893	8.9
Breast	YMB1	10
Breast	ZR751	10
Breast	ZR7530	10.7
Central nervous system	1321N1	9.3
Central nervous system	42MGBA	9.7
Central nervous system	8MGBA	9.7
Central nervous system	A172	9.3
Central nervous system	AM38	10.4
Central nervous system	BECKER	9.6
Central nervous system	CAS1	9.2
Central nervous system	CCFSTTG1	10.3
Central nervous system	D283MED	9.7
Central nervous system	D341MED	8.7
Central nervous system	DAOY	10.4
Central nervous system	DBTRG05MG	9.5
Central nervous system	DKMG	9.3
Central nervous system	GAMG	9.3
Central nervous system	GB1	10.1
Central nervous system	GI1	9.1
Central nervous system	GMS10	10.5
Central nervous system	GOS3	8.7
Central nervous system	H4	9
Central nervous system	HS683	9.5
Central nervous system	KALS1	9.8
Central nervous system	KG1C	8.3
Central nervous system	KNS42	9.4
Central nervous system	KNS60	10.1
Central nervous system	KNS81	8.7
Central nervous system	KS1	9.6
Central nervous system	LN18	10.2
Central nervous system	LN229	9.7
Central nervous system	M059K	10
Central nervous system	MOGGCCM	9.7
Central nervous system	MOGGUVW	9.3
Central nervous system	NMCG1	11
Central nervous system	ONS76	8.4
Central nervous system	SF126	9.5
Central nervous system	SF295	9.1
Central nervous system	SNB19	9.8
Central nervous system	SNU1105	9.7
Central nervous system	SNU201	9.4
Central nervous system	SNU466	9
Central nervous system	SNU489	9.1
Central nervous system	SNU626	9.8
Central nervous system	SNU738	8.7
Central nervous system	SW1088	9.6
Central nervous system	SW1783	9.7
Central nervous system	T98G	8.8
Central nervous system	TM31	9.7
Central nervous system	U118MG	9.7
Central nervous system	U138MG	9
Central nervous system	U251MG	9.3
Central nervous system	U87MG	9.9
Central nervous system	YH13	10
Central nervous system	YKG1	9.4
Endometrium	AN3CA	10.1
Endometrium	COLO684	11.3
Endometrium	EFE184	7.6
Endometrium	EN	8.7
Endometrium	ESS1	9.6
Endometrium	HEC108	8.4
Endometrium	HEC151	8.9
Endometrium	HEC1A	9.5
Endometrium	HEC1B	9.3
Endometrium	HEC251	8.5
Endometrium	HEC265	9.3
Endometrium	HEC50B	9.5
Endometrium	HEC59	9.8
Endometrium	HEC6	9.5
Endometrium	ISHIKAWAHERAKLIO02ER	9.8
Endometrium	JHUEM1	9.3
Endometrium	JHUEM2	9.5
Endometrium	JHUEM3	8.9
Endometrium	KLE	8.9
Endometrium	MFE280	10
Endometrium	MFE296	9.8
Endometrium	MFE319	9.4
Endometrium	RL952	9.1
Endometrium	SNGM	8.8
Endometrium	SNU1077	7.8
Endometrium	SNU685	8.6
Endometrium	TEN	9.2
Haematopoietic and lymphoid	697	10.4
Haematopoietic and lymphoid	A3KAW	10
Haematopoietic and lymphoid	A4FUK	9.7
Haematopoietic and lymphoid	ALLSIL	11.2
Haematopoietic and lymphoid	AML193	10.3
Haematopoietic and lymphoid	AMO1	10
Haematopoietic and lymphoid	BCP1	10.3
Haematopoietic and lymphoid	BDCM	9.9
Haematopoietic and lymphoid	BL41	10.2
Haematopoietic and lymphoid	BL70	10.2
Haematopoietic and lymphoid	BV173	9.7
Haematopoietic and lymphoid	CA46	10.3
Haematopoietic and lymphoid	CI1	10.3
Haematopoietic and lymphoid	CMK115	9.6
Haematopoietic and lymphoid	CMK86	9.7
Haematopoietic and lymphoid	CMK	9.3
Haematopoietic and lymphoid	CMLT1	10.4
Haematopoietic and lymphoid	COLO775	8.8
Haematopoietic and lymphoid	DAUDI	10.9
Haematopoietic and lymphoid	DB	9.9
Haematopoietic and lymphoid	DEL	9.4
Haematopoietic and lymphoid	DND41	11.2
Haematopoietic and lymphoid	DOHH2	10.4
Haematopoietic and lymphoid	EB1	9.8
Haematopoietic and lymphoid	EB2	9.8
Haematopoietic and lymphoid	EHEB	9.7
Haematopoietic and lymphoid	EJM	11.3
Haematopoietic and lymphoid	EM2	9.5
Haematopoietic and lymphoid	EOL1	10.1
Haematopoietic and lymphoid	F36P	9.7
Haematopoietic and lymphoid	GA10	10.1
Haematopoietic and lymphoid	GDM1	10.1
Haematopoietic and lymphoid	GRANTA519	10.6
Haematopoietic and lymphoid	HDLM2	10.1
Haematopoietic and lymphoid	HDMYZ	8.7
Haematopoietic and lymphoid	HEL9217	9.6
Haematopoietic and lymphoid	HEL	9.4
Haematopoietic and lymphoid	HH	9.8
Haematopoietic and lymphoid	HL60	9.9
Haematopoietic and lymphoid	HPBALL	11
Haematopoietic and lymphoid	HS604T	8.3
Haematopoietic and lymphoid	HS611T	9.8
Haematopoietic and lymphoid	HS616T	8.5
Haematopoietic and lymphoid	HS751T	9.1
Haematopoietic and lymphoid	HT	9.9
Haematopoietic and lymphoid	HTK	10.3
Haematopoietic and lymphoid	HUNS1	9.6
Haematopoietic and lymphoid	HUT102	9.4
Haematopoietic and lymphoid	HUT78	10.1
Haematopoietic and lymphoid	JEKO1	11.2
Haematopoietic and lymphoid	JK1	9.4
Haematopoietic and lymphoid	JM1	10.3
Haematopoietic and lymphoid	JURKAT	10.5
Haematopoietic and lymphoid	JURLMK1	9.6
Haematopoietic and lymphoid	JVM2	9.8
Haematopoietic and lymphoid	JVM3	9.5
Haematopoietic and lymphoid	K562	9.5
Haematopoietic and lymphoid	KARPAS299	9.6
Haematopoietic and lymphoid	KARPAS422	10
Haematopoietic and lymphoid	KARPAS620	10.5
Haematopoietic and lymphoid	KASUMI1	10
Haematopoietic and lymphoid	KASUMI2	9.3
Haematopoietic and lymphoid	KASUMI6	10
Haematopoietic and lymphoid	KCL22	10.5
Haematopoietic and lymphoid	KE37	10.7
Haematopoietic and lymphoid	KE97	9.8
Haematopoietic and lymphoid	KG1	10.1
Haematopoietic and lymphoid	KHM1B	9.7
Haematopoietic and lymphoid	KIJK	9.6
Haematopoietic and lymphoid	KMH2	11
Haematopoietic and lymphoid	KMM1	9.6
Haematopoietic and lymphoid	KMS11	9.3
Haematopoietic and lymphoid	KMS12BM	10.6
Haematopoietic and lymphoid	KMS18	9.6
Haematopoietic and lymphoid	KMS20	10.4
Haematopoietic and lymphoid	KMS21BM	9.3
Haematopoietic and lymphoid	KMS26	9.9
Haematopoietic and lymphoid	KMS27	10.1
Haematopoietic and lymphoid	KMS28BM	10
Haematopoietic and lymphoid	KMS34	9.3
Haematopoietic and lymphoid	KO52	9.2
Haematopoietic and lymphoid	KOPN8	10.7
Haematopoietic and lymphoid	KU812	10.4
Haematopoietic and lymphoid	KYO1	9
Haematopoietic and lymphoid	L1236	9.3
Haematopoietic and lymphoid	L363	9.1
Haematopoietic and lymphoid	L428	9.9
Haematopoietic and lymphoid	L540	10.5
Haematopoietic and lymphoid	LAMA84	9.7
Haematopoietic and lymphoid	LOUCY	10.3
Haematopoietic and lymphoid	LP1	9.3
Haematopoietic and lymphoid	M07E	10.1
Haematopoietic and lymphoid	MC116	10.2
Haematopoietic and lymphoid	ME1	10
Haematopoietic and lymphoid	MEC1	10.4
Haematopoietic and lymphoid	MEC2	10.7
Haematopoietic and lymphoid	MEG01	9.4
Haematopoietic and lymphoid	MHHCALL2	10.1
Haematopoietic and lymphoid	MHHCALL3	10.4
Haematopoietic and lymphoid	MHHCALL4	10.4
Haematopoietic and lymphoid	MINO	10.1
Haematopoietic and lymphoid	MJ	10
Haematopoietic and lymphoid	MM1S	9.5
Haematopoietic and lymphoid	MOLM13	10.1
Haematopoietic and lymphoid	MOLM16	9.9
Haematopoietic and lymphoid	MOLM6	9.8
Haematopoietic and lymphoid	MOLP2	8.8
Haematopoietic and lymphoid	MOLP8	9.6
Haematopoietic and lymphoid	MOLT13	10.6
Haematopoietic and lymphoid	MOLT16	10.2
Haematopoietic and lymphoid	MOLT4	10.9
Haematopoietic and lymphoid	MONOMAC1	10.1
Haematopoietic and lymphoid	MONOMAC6	10.4
Haematopoietic and lymphoid	MOTN1	10
Haematopoietic and lymphoid	MUTZ5	10.7
Haematopoietic and lymphoid	MV411	10.2
Haematopoietic and lymphoid	NALM19	10.5
Haematopoietic and lymphoid	NALM1	10.3
Haematopoietic and lymphoid	NALM6	10.6
Haematopoietic and lymphoid	NAMALWA	9.9
Haematopoietic and lymphoid	NB4	9.8
Haematopoietic and lymphoid	NCIH929	9.1
Haematopoietic and lymphoid	NCO2	9.9
Haematopoietic and lymphoid	NOMO1	9.7
Haematopoietic and lymphoid	NUDHL1	9.3
Haematopoietic and lymphoid	NUDUL1	9.3
Haematopoietic and lymphoid	OCIAML2	10.2
Haematopoietic and lymphoid	OCIAML3	9.9
Haematopoietic and lymphoid	OCIAML5	9.9
Haematopoietic and lymphoid	OCILY10	10.5
Haematopoietic and lymphoid	OCILY19	10.1
Haematopoietic and lymphoid	OCILY3	9.8
Haematopoietic and lymphoid	OCIM1	9.5
Haematopoietic and lymphoid	OPM2	10.5
Haematopoietic and lymphoid	P12ICHIKAWA	10.4
Haematopoietic and lymphoid	P31FUJ	10.1
Haematopoietic and lymphoid	P3HR1	10.1
Haematopoietic and lymphoid	PCM6	10
Haematopoietic and lymphoid	PEER	10.5
Haematopoietic and lymphoid	PF382	11.3
Haematopoietic and lymphoid	PFEIFFER	10.2
Haematopoietic and lymphoid	PL21	10.1
Haematopoietic and lymphoid	RAJI	9.7
Haematopoietic and lymphoid	RCHACV	10.6
Haematopoietic and lymphoid	REC1	9.7
Haematopoietic and lymphoid	REH	10.8
Haematopoietic and lymphoid	RI1	10.4
Haematopoietic and lymphoid	RL	9.8
Haematopoietic and lymphoid	RPMI8226	9.4
Haematopoietic and lymphoid	RPMI8402	10.3
Haematopoietic and lymphoid	RS411	10.6
Haematopoietic and lymphoid	SEM	10.8
Haematopoietic and lymphoid	SET2	9.9
Haematopoietic and lymphoid	SIGM5	10.1
Haematopoietic and lymphoid	SKM1	9.6
Haematopoietic and lymphoid	SKMM2	10.3
Haematopoietic and lymphoid	SR786	10
Haematopoietic and lymphoid	ST486	10.4
Haematopoietic and lymphoid	SUDHL10	10.3
Haematopoietic and lymphoid	SUDHL1	9.6
Haematopoietic and lymphoid	SUDHL4	10.2
Haematopoietic and lymphoid	SUDHL5	10.6
Haematopoietic and lymphoid	SUDHL6	10.6
Haematopoietic and lymphoid	SUDHL8	10.5
Haematopoietic and lymphoid	SUPB15	10.4
Haematopoietic and lymphoid	SUPHD1	10.2
Haematopoietic and lymphoid	SUPM2	9.4
Haematopoietic and lymphoid	SUPT11	10.6
Haematopoietic and lymphoid	SUPT1	10.4
Haematopoietic and lymphoid	TALL1	11.1
Haematopoietic and lymphoid	TF1	10
Haematopoietic and lymphoid	THP1	10
Haematopoietic and lymphoid	TO175T	8.9
Haematopoietic and lymphoid	TOLEDO	10.2
Haematopoietic and lymphoid	U266B1	10.9
Haematopoietic and lymphoid	U937	9.9
Haematopoietic and lymphoid	UT7	9.5
Haematopoietic and lymphoid	WSUDLCL2	11.1
Kidney	769P	8.8
Kidney	786O	8.8
Kidney	A498	9.2
Kidney	A704	8.9
Kidney	ACHN	8.6
Kidney	BFTC909	8.5
Kidney	CAKI1	7.9
Kidney	CAKI2	9.1
Kidney	CAL54	8.8
Kidney	KMRC1	9.5
Kidney	KMRC20	8.9
Kidney	KMRC2	9.3
Kidney	KMRC3	9.9
Kidney	OSRC2	8.9
Kidney	RCC10RGB	8.7
Kidney	SNU1272	8.4
Kidney	SNU349	9.4
Kidney	TUHR10TKB	9.5
Kidney	TUHR14TKB	9.3
Kidney	TUHR4TKB	7.9
Kidney	VMRCRCW	8.4
Kidney	VMRCRCZ	8.5
Large intestine	C2BBE1	8.4
Large intestine	CCK81	9.6
Large intestine	CL11	9.3
Large intestine	CL14	8.1
Large intestine	CL34	9.7
Large intestine	CL40	8.8
Large intestine	COLO205	9.6
Large intestine	COLO320	9.4
Large intestine	COLO678	9.6
Large intestine	CW2	9.6
Large intestine	DLD1	9.7
Large intestine	GP2D	9.7
Large intestine	HCC56	8.4
Large intestine	HCT116	9.7
Large intestine	HCT15	9.8
Large intestine	HS675T	9
Large intestine	HS698T	9.4
Large intestine	HT115	9.4
Large intestine	HT29	9
Large intestine	HT55	9.4
Large intestine	KM12	9.4
Large intestine	LOVO	9.2
Large intestine	LS1034	9
Large intestine	LS123	8.7
Large intestine	LS180	9.1
Large intestine	LS411N	9.6
Large intestine	LS513	9.3
Large intestine	MDST8	10.1
Large intestine	NCIH508	8
Large intestine	NCIH716	10.3
Large intestine	NCIH747	8.8
Large intestine	OUMS23	7.6
Large intestine	RCM1	8.5
Large intestine	RKO	9.9
Large intestine	SKCO1	9.6
Large intestine	SNU1040	9.5
Large intestine	SNU1197	8.6
Large intestine	SNU175	9.6
Large intestine	SNU283	9.5
Large intestine	SNU407	9.5
Large intestine	SNU503	9.7
Large intestine	SNU61	9.9
Large intestine	SNU81	9.3
Large intestine	SNUC1	9.3
Large intestine	SNUC2A	9.9
Large intestine	SNUC4	9.6
Large intestine	SNUC5	9.4
Large intestine	SW1116	8.4
Large intestine	SW1417	9.4
Large intestine	SW1463	9.6
Large intestine	SW403	9.5
Large intestine	SW480	9.6
Large intestine	SW48	9.3
Large intestine	SW620	9.8
Large intestine	SW837	9.3
Large intestine	SW948	9.2
Large intestine	T84	9.5
Liver	ALEXANDERCELLS	8.6
Liver	C3A	8.8
Liver	HEP3B217	8.3
Liver	HEPG2	9.2
Liver	HLE	9.3
Liver	HLF	8.8
Liver	HUH1	8
Liver	HUH6	8.7
Liver	HUH7	8.1
Liver	JHH1	9.2
Liver	JHH2	8.2
Liver	JHH4	9
Liver	JHH5	8.7
Liver	JHH6	9.3
Liver	JHH7	8.2
Liver	LI7	9.2
Liver	PLCPRF5	8.9
Liver	SKHEP1	9.4
Liver	SNU182	8.8
Liver	SNU387	9.2
Liver	SNU398	10.8
Liver	SNU423	9.5
Liver	SNU449	9.3
Liver	SNU475	9.5
Liver	SNU761	7.8
Liver	SNU878	8
Liver	SNU886	8.8
Lung	A549	9
Lung	ABC1	9.1
Lung	BEN	9.1
Lung	CAL12T	9.9
Lung	CALU1	10.1
Lung	CALU3	8.6
Lung	CALU6	9.6
Lung	CHAGOK1	9.9
Lung	COLO668	11.2
Lung	COLO699	9.5
Lung	CORL105	9.7
Lung	CORL23	8.6
Lung	CORL24	10.9
Lung	CORL279	10.1
Lung	CORL311	10
Lung	CORL47	11.5
Lung	CORL51	10.7
Lung	CORL88	10.9
Lung	CORL95	10.9
Lung	CPCN	10.6
Lung	DMS114	9.2
Lung	DMS153	10.1
Lung	DMS273	10.1
Lung	DMS454	10.5
Lung	DMS53	8.8
Lung	DMS79	11.3
Lung	DV90	9.1
Lung	EBC1	10.1
Lung	EPLC272H	8.9
Lung	HARA	10.3
Lung	HCC1171	9.9
Lung	HCC1195	9
Lung	HCC15	9.7
Lung	HCC2279	9
Lung	HCC2935	10.6
Lung	HCC33	11.4
Lung	HCC366	9.5
Lung	HCC4006	11.1
Lung	HCC44	9
Lung	HCC78	9.6
Lung	HCC827	8.9
Lung	HCC95	9.4
Lung	HLC1	9.4
Lung	HLFA	8.8
Lung	HS229T	9.5
Lung	HS618T	9.3
Lung	IALM	9.6
Lung	KNS62	9
Lung	LC1F	9.1
Lung	LC1SQSF	9.3
Lung	LCLC103H	9.3
Lung	LCLC97TM1	9.6
Lung	LK2	9.4
Lung	LOUNH91	8.3
Lung	LU65	9.6
Lung	LU99	9.7
Lung	LUDLU1	9.6
Lung	LXF289	8.5
Lung	MORCPR	8.7
Lung	NCIH1048	10.3
Lung	NCIH1092	11
Lung	NCIH1105	11.1
Lung	NCIH1155	10.5
Lung	NCIH1184	10.4
Lung	NCIH1299	10.6
Lung	NCIH1339	9.7
Lung	NCIH1341	10.2
Lung	NCIH1355	9.1
Lung	NCIH1373	9.2
Lung	NCIH1385	10.2
Lung	NCIH1395	9.8
Lung	NCIH1435	8.9
Lung	NCIH1436	10.3
Lung	NCIH1437	9.8
Lung	NCIH146	10.1
Lung	NCIH1563	9.6
Lung	NCIH1568	9.7
Lung	NCIH1573	8.6
Lung	NCIH1581	9.9
Lung	NCIH1618	10.3
Lung	NCIH1623	9.4
Lung	NCIH1648	8.4
Lung	NCIH1650	8.8
Lung	NCIH1651	8.5
Lung	NCIH1666	8.4
Lung	NCIH1693	8.6
Lung	NCIH1694	11.3
Lung	NCIH1703	9
Lung	NCIH1734	10.1
Lung	NCIH1755	9.1
Lung	NCIH1781	10.4
Lung	NCIH1792	9.5
Lung	NCIH1793	9.5
Lung	NCIH1836	10.9
Lung	NCIH1838	9
Lung	NCIH1869	9.2
Lung	NCIH1876	10.8
Lung	NCIH1915	9.7
Lung	NCIH1930	9.7
Lung	NCIH1944	8.8
Lung	NCIH1963	10.9
Lung	NCIH196	10.4
Lung	NCIH1975	9.6
Lung	NCIH2009	9
Lung	NCIH2023	8.5
Lung	NCIH2029	9.6
Lung	NCIH2030	9.8
Lung	NCIH2066	9.4
Lung	NCIH2081	11.1
Lung	NCIH2085	8.2
Lung	NCIH2087	8.9
Lung	NCIH209	10.6
Lung	NCIH2106	11.1
Lung	NCIH2110	9.2
Lung	NCIH211	10.3
Lung	NCIH2122	9
Lung	NCIH2126	9
Lung	NCIH2141	11.8
Lung	NCIH2170	9.4
Lung	NCIH2171	10.7
Lung	NCIH2172	9.9
Lung	NCIH2196	9.4
Lung	NCIH2227	10.6
Lung	NCIH2228	10.3
Lung	NCIH226	8.8
Lung	NCIH2286	9.4
Lung	NCIH2291	8.5
Lung	NCIH2342	8.5
Lung	NCIH2347	9.7
Lung	NCIH23	8.5
Lung	NCIH2405	9.4
Lung	NCIH2444	9.7
Lung	NCIH292	9.2
Lung	NCIH322	8.7
Lung	NCIH3255	9.8
Lung	NCIH358	9.9
Lung	NCIH441	9.2
Lung	NCIH446	10.4
Lung	NCIH460	10.2
Lung	NCIH510	9.9
Lung	NCIH520	9.4
Lung	NCIH522	9.6
Lung	NCIH524	11.2
Lung	NCIH526	10.1
Lung	NCIH596	9.8
Lung	NCIH647	9.5
Lung	NCIH650	8.7
Lung	NCIH661	9.3
Lung	NCIH69	10.9
Lung	NCIH727	10
Lung	NCIH810	10
Lung	NCIH82	9.5
Lung	NCIH838	9.5
Lung	NCIH841	9.1
Lung	NCIH854	9.3
Lung	NCIH889	11.3
Lung	PC14	7.8
Lung	RERFLCAD1	9
Lung	RERFLCAD2	9
Lung	RERFLCAI	9.7
Lung	RERFLCKJ	9.3
Lung	RERFLCMS	8.9
Lung	RERFLCSQ1	9.6
Lung	SBC5	8.7
Lung	SCLC21H	10.5
Lung	SHP77	10.3
Lung	SKLU1	9.8
Lung	SKMES1	9
Lung	SQ1	8.9
Lung	SW1271	10.1
Lung	SW1573	9.9
Lung	SW900	9.8
Lung	VMRCLCD	9.2
Lung	VMRCLCP	9.8
Oesophagus	COLO680N	9.4
Oesophagus	ECGI10	8.1
Oesophagus	KYSE140	9.4
Oesophagus	KYSE150	9.4
Oesophagus	KYSE180	10.2
Oesophagus	KYSE270	9.6
Oesophagus	KYSE30	6.4
Oesophagus	KYSE410	9
Oesophagus	KYSE450	8.2
Oesophagus	KYSE510	8.4
Oesophagus	KYSE520	9.1
Oesophagus	KYSE70	8.6
Oesophagus	OE19	9.5
Oesophagus	OE33	9
Oesophagus	TE10	10.6
Oesophagus	TE11	10
Oesophagus	TE14	10
Oesophagus	TE15	9.6
Oesophagus	TE1	8.9
Oesophagus	TE4	9.1
Oesophagus	TE5	9.7
Oesophagus	TE6	10.2
Oesophagus	TE8	9.7
Oesophagus	TE9	9.8
Oesophagus	TT	8.5
Ovary	59M	7.6
Ovary	A2780	9.6
Ovary	CAOV3	10.1
Ovary	CAOV4	8.1
Ovary	COLO704	10.6
Ovary	COV318	8.9
Ovary	COV362	9.6
Ovary	COV434	9.6
Ovary	COV504	8.8
Ovary	COV644	8.9
Ovary	EFO21	9.3
Ovary	EFO27	8.7
Ovary	ES2	9.6
Ovary	FUOV1	10.1
Ovary	HEYA8	9.1
Ovary	HS571T	8.9
Ovary	IGROV1	9.7
Ovary	JHOC5	9
Ovary	JHOM1	9.2
Ovary	JHOM2B	9.6
Ovary	JHOS2	9.2
Ovary	JHOS4	9.4
Ovary	KURAMOCHI	8.3
Ovary	MCAS	9.2
Ovary	NIHOVCAR3	9.2
Ovary	OAW28	9.8
Ovary	OAW42	10.1
Ovary	OC314	9.3
Ovary	OC316	9.1
Ovary	ONCODG1	9
Ovary	OV56	8.5
Ovary	OV7	9.9
Ovary	OV90	9
Ovary	OVCAR4	9.1
Ovary	OVCAR8	9.1
Ovary	OVISE	8.5
Ovary	OVK18	10.1
Ovary	OVKATE	9.8
Ovary	OVMANA	7.7
Ovary	OVSAHO	8.8
Ovary	OVTOKO	9.3
Ovary	RMGI	9.2
Ovary	RMUGS	9.4
Ovary	SKOV3	9.2
Ovary	SNU119	8.7
Ovary	SNU840	9.5
Ovary	SNU8	9.3
Ovary	TOV112D	10.1
Ovary	TOV21G	8.7
Ovary	TYKNU	9.1
Pancreas	ASPC1	7.5
Pancreas	BXPC3	9.4
Pancreas	CAPAN1	9.4
Pancreas	CAPAN2	9.3
Pancreas	CFPAC1	8.9
Pancreas	DANG	8.9
Pancreas	HPAC	8.1
Pancreas	HPAFII	9.2
Pancreas	HS766T	8.9
Pancreas	HUPT3	9
Pancreas	HUPT4	9.7
Pancreas	KCIMOH1	7.7
Pancreas	KLM1	9.6
Pancreas	KP2	8.7
Pancreas	KP3	8.4
Pancreas	KP4	9.4
Pancreas	L33	9.8
Pancreas	MIAPACA2	9.3
Pancreas	PANC0203	9.1
Pancreas	PANC0213	8.6
Pancreas	PANC0327	9.3
Pancreas	PANC0403	9.3
Pancreas	PANC0504	9.7
Pancreas	PANC0813	8.9
Pancreas	PANC1005	9.7
Pancreas	PANC1	9
Pancreas	PATU8902	8.8
Pancreas	PATU8988S	9.8
Pancreas	PATU8988T	10.1
Pancreas	PK1	9.6
Pancreas	PK45H	9.4
Pancreas	PK59	8.8
Pancreas	PL45	9.4
Pancreas	PSN1	9.5
Pancreas	QGP1	8.9
Pancreas	SNU213	9.2
Pancreas	SNU324	9.7
Pancreas	SNU410	9.2
Pancreas	SU8686	8
Pancreas	SUIT2	9.5
Pancreas	SW1990	9.5
Pancreas	T3M4	8.8
Pancreas	TCCPAN2	9.9
Pancreas	YAPC	10.1
Pleura	ACCMESO1	8.6
Pleura	DM3	9
Pleura	ISTMES1	9.5
Pleura	ISTMES2	9.6
Pleura	JL1	8
Pleura	MPP89	9.3
Pleura	MSTO211H	9.3
Pleura	NCIH2052	9.5
Pleura	NCIH2452	9
Pleura	NCIH28	8.9
Prostate	22RV1	10.4
Prostate	DU145	9.9
Prostate	LNCAPCLONEFGC	9.3
Prostate	MDAPCA2B	9.7
Prostate	NCIH660	10.5
Prostate	PC3	9.6
Prostate	VCAP	9.3
Salivary gland	A253	9.7
Salivary gland	YD15	9.5
Skin	A101D	9.3
Skin	A2058	10.1
Skin	A375	9.7
Skin	C32	10
Skin	CHL1	9.3
Skin	CJM	8.6
Skin	COLO679	9
Skin	COLO741	8.8
Skin	COLO783	9.1
Skin	COLO792	9.1
Skin	COLO800	9.2
Skin	COLO818	8.7
Skin	COLO829	9.3
Skin	COLO849	9.7
Skin	G361	8.5
Skin	GRM	9.2
Skin	HMCB	9.9
Skin	HS294T	9.3
Skin	HS600T	8
Skin	HS688AT	8.7
Skin	HS695T	9.1
Skin	HS839T	9.3
Skin	HS852T	10
Skin	HS895T	8.8
Skin	HS934T	9.7
Skin	HS936T	9.4
Skin	HS939T	9.4
Skin	HS940T	8.3
Skin	HS944T	9.8
Skin	HT144	9.3
Skin	IGR1	9.3
Skin	IGR37	9.3
Skin	IGR39	9.7
Skin	IPC298	9.5
Skin	K029AX	8.5
Skin	LOXIMVI	9.1
Skin	MALME3M	9.1
Skin	MDAMB435S	10
Skin	MELHO	9.4
Skin	MELJUSO	9.1
Skin	MEWO	9.7
Skin	RPMI7951	9.6
Skin	RVH421	8.9
Skin	SH4	9.5
Skin	SKMEL1	8.2
Skin	SKMEL24	9.4
Skin	SKMEL28	9
Skin	SKMEL2	9.8
Skin	SKMEL30	9.6
Skin	SKMEL31	8.6
Skin	SKMEL3	9.3
Skin	SKMEL5	9.6
Skin	UACC257	9.5
Skin	UACC62	9.5
Skin	WM115	9
Skin	WM1799	10
Skin	WM2664	9.8
Skin	WM793	9.3
Skin	WM88	9.6
Skin	WM983B	9.1
Small intestine	HUTU80	9
Soft tissue	A204	9.2
Soft tissue	G401	10
Soft tissue	G402	9.4
Soft tissue	GCT	9.5
Soft tissue	HS729	8.9
Soft tissue	HT1080	10
Soft tissue	KYM1	9.6
Soft tissue	MESSA	9.8
Soft tissue	RD	9.3
Soft tissue	RH30	10.6
Soft tissue	RH41	9.9
Soft tissue	RKN	9.4
Soft tissue	S117	9.8
Soft tissue	SJRH30	9.5
Soft tissue	SKLMS1	10.1
Soft tissue	SKUT1	9.7
Soft tissue	TE125T	9.1
Soft tissue	TE159T	9.1
Soft tissue	TE441T	10
Soft tissue	TE617T	9.2
Stomach	2313287	9.6
Stomach	AGS	9.2
Stomach	AZ521	9.4
Stomach	ECC10	9.9
Stomach	ECC12	10.1
Stomach	FU97	8.6
Stomach	GCIY	8.5
Stomach	GSS	8.3
Stomach	GSU	9.5
Stomach	HGC27	10.4
Stomach	HS746T	10.3
Stomach	HUG1N	8.6
Stomach	IM95	9.7
Stomach	KATOIII	9.4
Stomach	KE39	9.3
Stomach	LMSU	9.9
Stomach	MKN1	9.7
Stomach	MKN45	9.9
Stomach	MKN74	8.1
Stomach	MKN7	8.2
Stomach	NCCSTCK140	8.7
Stomach	NCIN87	8.7
Stomach	NUGC2	9
Stomach	NUGC3	9.4
Stomach	NUGC4	8.7
Stomach	OCUM1	9.8
Stomach	RERFGC1B	8.7
Stomach	SH10TC	9.4
Stomach	SNU16	9.9
Stomach	SNU1	9.5
Stomach	SNU216	9.1
Stomach	SNU520	10.2
Stomach	SNU5	9.5
Stomach	SNU601	9.7
Stomach	SNU620	10.1
Stomach	SNU668	9.9
Stomach	SNU719	9.6
Stomach	TGBC11TKB	8.6
Thyroid	8305C	10.3
Thyroid	8505C	10.3
Thyroid	BCPAP	8.7
Thyroid	BHT101	8.1
Thyroid	CAL62	8.8
Thyroid	CGTHW1	9.8
Thyroid	FTC133	10.3
Thyroid	FTC238	9.4
Thyroid	ML1	8.6
Thyroid	SW579	9.8
Thyroid	TT2609C02	10.4
Thyroid	TT	9.7
Upper aerodigestive tract	BHY	8.6
Upper aerodigestive tract	BICR16	9.8
Upper aerodigestive tract	BICR18	8.8
Upper aerodigestive tract	BICR22	7.9
Upper aerodigestive tract	BICR31	9.2
Upper aerodigestive tract	BICR56	6.8
Upper aerodigestive tract	BICR6	9.4
Upper aerodigestive tract	CAL27	9.1
Upper aerodigestive tract	CAL33	8.7
Upper aerodigestive tract	DETROIT562	9.8
Upper aerodigestive tract	FADU	11.4
Upper aerodigestive tract	HS840T	9.3
Upper aerodigestive tract	HSC2	8.6
Upper aerodigestive tract	HSC3	9.9
Upper aerodigestive tract	HSC4	9.4
Upper aerodigestive tract	PECAPJ15	9
Upper aerodigestive tract	PECAPJ34CLONEC12	10.3
Upper aerodigestive tract	PECAPJ41CLONED2	7.7
Upper aerodigestive tract	PECAPJ49	9.1
Upper aerodigestive tract	SCC15	8.2
Upper aerodigestive tract	SCC25	9.7
Upper aerodigestive tract	SCC4	9.5
Upper aerodigestive tract	SCC9	8.6
Upper aerodigestive tract	SNU1076	8.8
Upper aerodigestive tract	SNU1214	10
Upper aerodigestive tract	SNU46	10.3
Upper aerodigestive tract	SNU899	8.9
Upper aerodigestive tract	YD10B	8.6
Upper aerodigestive tract	YD38	9.1
Upper aerodigestive tract	YD8	9.2
Urinary tract	5637	9.3
Urinary tract	639V	10.3
Urinary tract	647V	9.5
Urinary tract	BC3C	9.9
Urinary tract	BFTC905	9.2
Urinary tract	CAL29	9.6
Urinary tract	HS172T	9.1
Urinary tract	HT1197	8.6
Urinary tract	HT1376	9.2
Urinary tract	J82	9.4
Urinary tract	JMSU1	10.1
Urinary tract	KMBC2	10.4
Urinary tract	KU1919	9.6
Urinary tract	RT11284	9.9
Urinary tract	RT112	9.8
Urinary tract	RT4	9.9
Urinary tract	SCABER	8.5
Urinary tract	SW1710	8
Urinary tract	SW780	9.5
Urinary tract	T24	10.2
Urinary tract	TCCSUP	8.9
Urinary tract	UMUC1	9
Urinary tract	UMUC3	9.8
Urinary tract	VMCUB1	8.6

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	7
Adrenal gland	6.5
Appendix	8.9
Bone marrow	6.7
Breast	11.3
Cerebral cortex	19.5
Cervix, uterine	12.8
Colon	8.6
Duodenum	6.1
Endometrium	11.9
Epididymis	8
Esophagus	6.9
Fallopian tube	11.2
Gallbladder	9.8
Heart muscle	7
Kidney	8.4
Liver	3.6
Lung	9.1
Lymph node	12.5
Ovary	10.6
Pancreas	2.3
Parathyroid gland	22.8
Placenta	7
Prostate	11.2
Rectum	9.9
Salivary gland	2.5
Seminal vesicle	10.1
Skeletal muscle	2.5
Skin	8.9
Small intestine	7.2
Smooth muscle	10.7
Spleen	9.6
Stomach	6.6
Testis	14.6
Thyroid gland	13.4
Tonsil	12.4
Urinary bladder	7.8

> Text Mining based Expression [ TOP ]
There is no record.

Summary
Symbol	UBR7
Name	ubiquitin protein ligase E3 component n-recognin 7 (putative)
Aliases	C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7
Location	14q32.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.622	1.1e-44	30.7	52.2	17.1	Neutral
BRCA	Breast invasive carcinoma	1075	0.536	4.97e-81	30	56.7	13.3	Neutral
CESC	Cervical and endocervical cancers	292	0.7	2.25e-44	16.4	66.1	17.5	Neutral
COAD	Colon adenocarcinoma	449	0.557	6.25e-38	33.4	59.5	7.1	Loss
ESCA	Esophageal carcinoma	183	0.671	2.44e-25	32.2	41	26.8	Neutral
GBM	Glioblastoma multiforme	147	0.701	4.37e-23	33.3	61.2	5.4	Neutral
HNSC	Head and Neck squamous cell carcinoma	514	0.474	4.32e-30	13.6	55.3	31.1	Neutral
KIRC	Kidney renal clear cell carcinoma	525	0.611	4.25e-55	42.5	54.5	3	Loss
KIRP	Kidney renal papillary cell carcinoma	288	0.458	2.28e-16	17	81.9	1	Neutral
LAML	Acute Myeloid Leukemia	166	-0.022	0.783	0	98.8	1.2	Neutral
LGG	Brain Lower Grade Glioma	513	0.659	3.6e-65	22	77.2	0.8	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.525	3.49e-27	35.2	58.8	6	Loss
LUAD	Lung adenocarcinoma	512	0.656	3.27e-64	27.9	48.4	23.6	Neutral
LUSC	Lung squamous cell carcinoma	498	0.601	2.6e-50	32.3	38.8	28.9	Neutral
OV	Ovarian serous cystadenocarcinoma	300	0.664	1.41e-39	40.3	38.7	21	Loss
PAAD	Pancreatic adenocarcinoma	177	0.57	1.14e-16	9.6	74.6	15.8	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	0.567	3.47e-15	13.6	82.1	4.3	Neutral
PRAD	Prostate adenocarcinoma	491	0.474	7.21e-29	8.8	87.8	3.5	Neutral
READ	Rectum adenocarcinoma	164	0.543	6.02e-14	41.5	51.8	6.7	Loss
SARC	Sarcoma	255	0.518	6.16e-19	27.1	48.6	24.3	Neutral
SKCM	Skin Cutaneous Melanoma	367	0.605	4.85e-38	31.9	55.6	12.5	Neutral
STAD	Stomach adenocarcinoma	413	0.529	3.22e-31	29.1	62.2	8.7	Neutral
TGCT	Testicular Germ Cell Tumors	150	0.435	2.66e-08	15.3	48.7	36	Gain
THCA	Thyroid carcinoma	497	0.194	1.31e-05	0.2	97.6	2.2	Neutral
THYM	Thymoma	119	0.246	0.00711	1.7	87.4	10.9	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.405	1.17e-22	11.5	77.3	11.2	Neutral

Summary
Symbol	UBR7
Name	ubiquitin protein ligase E3 component n-recognin 7 (putative)
Aliases	C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7
Location	14q32.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

[ TOP ]

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.256	9.16e-08	17	408	-0.261	1.43e-07	Decreased
BRCA	Breast invasive carcinoma	-0.33	0	83	785	0.001	3.23e-07	NS/NA
CESC	Cervical and endocervical cancers	-0.253	7.26e-06	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.212	0.000151	19	297	-0.049	0.0249	NS/NA
ESCA	Esophageal carcinoma	-0.193	0.00724	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.166	0.186	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.366	0	20	522	-0.139	1.89e-06	NS/NA
KIRC	Kidney renal clear cell carcinoma	-0.175	0.00118	24	319	0.002	2.3e-10	NS/NA
KIRP	Kidney renal papillary cell carcinoma	-0.181	0.00174	23	275	0.002	0.989	NS/NA
LAML	Acute Myeloid Leukemia	-0.009	0.904	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	-0.129	0.00295	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.231	2.09e-06	41	373	-0.351	3.07e-21	Decreased
LUAD	Lung adenocarcinoma	-0.165	0.000311	21	456	-0.205	2.39e-13	Decreased
LUSC	Lung squamous cell carcinoma	-0.397	2.22e-16	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	-0.667	0.0589	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.21	0.00448	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.162	0.0269	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.333	3.79e-15	35	498	-0.211	9.97e-10	Decreased
READ	Rectum adenocarcinoma	-0.401	3.85e-05	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.268	1.17e-05	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.34	4.4e-14	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.129	0.0126	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.151	0.0607	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.091	0.0312	50	509	0	0.965	NS/NA
THYM	Thymoma	-0.086	0.347	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.129	0.0052	34	431	-0.343	6.25e-18	Decreased

Summary
Symbol	UBR7
Name	ubiquitin protein ligase E3 component n-recognin 7 (putative)
Aliases	C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7
Location	14q32.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Level	Level Name
Adrenal gland	2	Medium
Appendix	3	High
Bone marrow	3	High
Breast	2	Medium
Bronchus	3	High
Caudate	2	Medium
Cerebellum	2	Medium
Cerebral cortex	2	Medium
Cervix, uterine	2	Medium
Colon	2	Medium
Duodenum	3	High
Endometrium	3	High
Epididymis	3	High
Esophagus	3	High
Fallopian tube	2	Medium
Gallbladder	2	Medium
Heart muscle	0	Not detected
Hippocampus	2	Medium
Kidney	2	Medium
Liver	1	Low
Lung	3	High
Lymph node	2	Medium
Nasopharynx	2	Medium
Oral mucosa	3	High
Ovary	2	Medium
Pancreas	2	Medium
Parathyroid gland	3	High
Placenta	3	High
Prostate	2	Medium
Rectum	3	High
Salivary gland	3	High
Seminal vesicle	3	High
Skeletal muscle	0	Not detected
Skin	2	Medium
Small intestine	2	Medium
Smooth muscle	2	Medium
Soft tissue	2	Medium
Spleen	2	Medium
Stomach	3	High
Testis	3	High
Thyroid gland	2	Medium
Tonsil	3	High
Urinary bladder	2	Medium
Vagina	2	Medium

Summary
Symbol	UBR7
Name	ubiquitin protein ligase E3 component n-recognin 7 (putative)
Aliases	C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7
Location	14q32.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.0103	Significant	24476821
BRCA	Breast invasive carcinoma	521	9.67e-15	Significant	23000897
COAD	Colon adenocarcinoma	149	3.07e-05	Significant	22810696
GBM	Glioblastoma multiforme	157	2.34e-05	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	0.00866	Significant	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.973	NS	26536169
LGG	Brain Lower Grade Glioma	513	6.57e-07	Significant	26824661
LUAD	Lung adenocarcinoma	230	0.255	NS	25079552
LUSC	Lung squamous cell carcinoma	178	0.00219	Significant	22960745
OV	Ovarian serous cystadenocarcinoma	287	0.188	NS	21720365
PRAD	Prostate adenocarcinoma	333	0.000852	Significant	26544944
READ	Rectum adenocarcinoma	67	0.392	NS	22810696
SKCM	Skin Cutaneous Melanoma	315	0.182	NS	26091043
STAD	Stomach adenocarcinoma	277	2.09e-09	Significant	25079317
THCA	Thyroid carcinoma	391	0.0415	Significant	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	3.8e-06	Significant	23636398

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	1.111	0.622	NS
BRCA	Breast invasive carcinoma	1079	1.12	0.606	NS
CESC	Cervical and endocervical cancers	291	0.675	0.285	NS
COAD	Colon adenocarcinoma	439	0.612	0.0821	NS
ESCA	Esophageal carcinoma	184	0.971	0.933	NS
GBM	Glioblastoma multiforme	158	0.845	0.504	NS
HNSC	Head and Neck squamous cell carcinoma	518	1.149	0.476	NS
KIRC	Kidney renal clear cell carcinoma	531	0.443	0.000118	Longer
KIRP	Kidney renal papillary cell carcinoma	287	0.355	0.0156	Longer
LAML	Acute Myeloid Leukemia	149	0.965	0.907	NS
LGG	Brain Lower Grade Glioma	511	1.002	0.992	NS
LIHC	Liver hepatocellular carcinoma	365	1.241	0.373	NS
LUAD	Lung adenocarcinoma	502	1.087	0.703	NS
LUSC	Lung squamous cell carcinoma	494	0.752	0.147	NS
OV	Ovarian serous cystadenocarcinoma	303	0.833	0.382	NS
PAAD	Pancreatic adenocarcinoma	177	0.865	0.612	NS
PCPG	Pheochromocytoma and Paraganglioma	179	673966449.887	0.0659	NS
PRAD	Prostate adenocarcinoma	497	1.031	0.971	NS
READ	Rectum adenocarcinoma	159	1.346	0.601	NS
SARC	Sarcoma	259	1.104	0.742	NS
SKCM	Skin Cutaneous Melanoma	459	1.103	0.596	NS
STAD	Stomach adenocarcinoma	388	0.944	0.8	NS
TGCT	Testicular Germ Cell Tumors	134	574088867.025	0.326	NS
THCA	Thyroid carcinoma	500	1.147	0.837	NS
THYM	Thymoma	119	0.217	0.175	NS
UCEC	Uterine Corpus Endometrial Carcinoma	543	0.778	0.408	NS

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	-0.001	0.98	NS
BRCA	Breast invasive carcinoma	1071	0.005	0.859	NS
CESC	Cervical and endocervical cancers	167	0.026	0.737	NS
COAD	Colon adenocarcinoma	445	-0.158	0.00083	Lower
ESCA	Esophageal carcinoma	162	-0.046	0.563	NS
HNSC	Head and Neck squamous cell carcinoma	448	-0.008	0.87	NS
KIRC	Kidney renal clear cell carcinoma	531	-0.152	0.000435	Lower
KIRP	Kidney renal papillary cell carcinoma	260	0.004	0.95	NS
LIHC	Liver hepatocellular carcinoma	347	0.105	0.0517	NS
LUAD	Lung adenocarcinoma	507	0.005	0.917	NS
LUSC	Lung squamous cell carcinoma	497	0.083	0.063	NS
OV	Ovarian serous cystadenocarcinoma	302	-0.008	0.894	NS
PAAD	Pancreatic adenocarcinoma	176	-0.093	0.221	NS
READ	Rectum adenocarcinoma	156	-0.023	0.774	NS
SKCM	Skin Cutaneous Melanoma	410	-0.111	0.0246	Lower
STAD	Stomach adenocarcinoma	392	-0.028	0.576	NS
TGCT	Testicular Germ Cell Tumors	81	0.057	0.615	NS
THCA	Thyroid carcinoma	499	0.051	0.26	NS
UCEC	Uterine Corpus Endometrial Carcinoma	501	0.037	0.411	NS

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	-0.115	0.0588	NS
HNSC	Head and Neck squamous cell carcinoma	498	0.14	0.0017	Higher
KIRC	Kidney renal clear cell carcinoma	525	-0.218	4.83e-07	Lower
LGG	Brain Lower Grade Glioma	514	0.003	0.947	NS
LIHC	Liver hepatocellular carcinoma	366	-0.087	0.0977	NS
OV	Ovarian serous cystadenocarcinoma	296	-0.029	0.624	NS
PAAD	Pancreatic adenocarcinoma	176	-0.141	0.0624	NS
STAD	Stomach adenocarcinoma	406	-0.051	0.303	NS
UCEC	Uterine Corpus Endometrial Carcinoma	534	0.197	4.32e-06	Higher

Summary
Symbol	UBR7
Name	ubiquitin protein ligase E3 component n-recognin 7 (putative)
Aliases	C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7
Location	14q32.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	UBR7
Name	ubiquitin protein ligase E3 component n-recognin 7 (putative)
Aliases	C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7
Location	14q32.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for UBR7.

Summary
Symbol	UBR7
Name	ubiquitin protein ligase E3 component n-recognin 7 (putative)
Aliases	C14orf130; chromosome 14 open reading frame 130; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7
Location	14q32.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining [ TOP ]
There is no record for UBR7.