Browse ZMYM3 in pancancer

Summary
Symbol	ZMYM3
Name	zinc finger MYM-type containing 3
Aliases	ZNF198L2; DXS6673E; KIAA0385; ZNF261; zinc finger protein 261; XFIM; Zinc finger MYM-type protein 3
Location	Xq13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

Domain

PF12012 Domain of unknown function (DUF3504)
PF06467 MYM-type Zinc finger with FCS sequence motif

Function

Plays a role in the regulation of cell morphology and cytoskeletal organization.

Classification

Class	Modification	Substrate	Product	PubMed
Histone modification erase cofactor	Histone acetylation	#	#	12493763

> Gene Ontology [ TOP ]
Biological Process	GO:0022604 regulation of cell morphogenesis
Molecular Function	-
Cellular Component	-

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	-

Summary
Symbol	ZMYM3
Name	zinc finger MYM-type containing 3
Aliases	ZNF198L2; DXS6673E; KIAA0385; ZNF261; zinc finger protein 261; XFIM; Zinc finger MYM-type protein 3
Location	Xq13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM3724250	c.2661G>A	p.P887P	Substitution - coding silent	Upper_aerodigestive_tract
COSM1178926	c.143_144insC	p.G49fs*13	Insertion - Frameshift	Autonomic_ganglia
COSM273498	c.3064C>T	p.P1022S	Substitution - Missense	Large_intestine
COSM3737488	c.2229C>A	p.C743*	Substitution - Nonsense	Soft_tissue
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM457977	c.3908A>G	p.Y1303C	Substitution - Missense	Breast
COSM3095629	c.193G>A	p.G65S	Substitution - Missense	Large_intestine
COSM1735242	c.143delC	p.P48fs*65	Deletion - Frameshift	Large_intestine
COSM1124807	c.2685G>A	p.P895P	Substitution - coding silent	Endometrium
COSM1293056	c.3905T>C	p.F1302S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3719816	c.3899A>G	p.Y1300C	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1124800	c.3250A>C	p.T1084P	Substitution - Missense	Endometrium
COSM2153280	c.1409T>C	p.L470P	Substitution - Missense	Central_nervous_system
COSM5413026	c.1754G>A	p.G585E	Substitution - Missense	Skin
COSM4435593	c.772G>A	p.E258K	Substitution - Missense	Oesophagus
COSM1469185	c.252delG	p.L85fs*28	Deletion - Frameshift	Breast
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM3563106	c.2809G>A	p.E937K	Substitution - Missense	Skin
COSM5030636	c.245_246insG	p.L85fs*4	Insertion - Frameshift	Bone
COSM1315668	c.881C>G	p.S294*	Substitution - Nonsense	Urinary_tract
COSM1715114	c.2719G>A	p.E907K	Substitution - Missense	Skin
COSM1233530	c.3205A>G	p.N1069D	Substitution - Missense	Large_intestine
COSM5715829	c.3450C>T	p.N1150N	Substitution - coding silent	Skin
COSM3965483	c.802G>C	p.D268H	Substitution - Missense	Lung
COSM255663	c.1939C>T	p.R647*	Substitution - Nonsense	Endometrium
COSM1757283	c.3602G>A	p.G1201E	Substitution - Missense	Urinary_tract
COSM5030636	c.245_246insG	p.L85fs*4	Insertion - Frameshift	Bone
COSM146125	c.2542G>A	p.V848M	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3379677	c.3317G>C	p.C1106S	Substitution - Missense	Pancreas
COSM248485	c.4064G>A	p.R1355H	Substitution - Missense	Prostate
COSM4381993	c.1300G>C	p.D434H	Substitution - Missense	Large_intestine
COSM5005363	c.2843_2844insCT	p.S950fs*8	Insertion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM5701738	c.1186_1187CC>AA	p.P396K	Substitution - Missense	Soft_tissue
COSM1124815	c.1487A>G	p.Y496C	Substitution - Missense	Endometrium
COSM1124819	c.683C>T	p.A228V	Substitution - Missense	Endometrium
COSM3767043	c.1068C>T	p.C356C	Substitution - coding silent	Liver
COSM1132268	c.199G>T	p.E67*	Substitution - Nonsense	Prostate
COSM4457338	c.1040C>T	p.P347L	Substitution - Missense	Skin
COSM4742912	c.3987G>A	p.E1329E	Substitution - coding silent	Large_intestine
COSM146124	c.3418C>G	p.L1140V	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1124808	c.2638C>T	p.H880Y	Substitution - Missense	Endometrium
COSM255676	c.3595C>G	p.Q1199E	Substitution - Missense	Central_nervous_system
COSM1469179	c.3271C>T	p.R1091C	Substitution - Missense	Large_intestine
COSM1124810	c.2242C>A	p.L748I	Substitution - Missense	Endometrium
COSM4879339	c.2923C>T	p.R975*	Substitution - Nonsense	Prostate
COSM4742913	c.3970C>T	p.R1324W	Substitution - Missense	Large_intestine
COSM1315671	c.515C>T	p.S172F	Substitution - Missense	Urinary_tract
COSM248486	c.3080delC	p.T1027fs*9	Deletion - Frameshift	Prostate
COSM3563109	c.2052G>T	p.Q684H	Substitution - Missense	Skin
COSM4742917	c.647C>G	p.P216R	Substitution - Missense	Large_intestine
COSM1469185	c.252delG	p.L85fs*28	Deletion - Frameshift	Prostate
COSM1124821	c.443C>A	p.S148Y	Substitution - Missense	Endometrium
COSM383655	c.1649G>T	p.R550L	Substitution - Missense	Lung
COSM3708718	c.724C>T	p.R242C	Substitution - Missense	Liver
COSM5702439	c.1656_1657CC>AA	p.S552_L553>RI	Complex - compound substitution	Soft_tissue
COSM1469183	c.1416C>T	p.H472H	Substitution - coding silent	Large_intestine
COSM4495125	c.446C>T	p.P149L	Substitution - Missense	Skin
COSM255320	c.3332delT	p.L1111fs*9	Deletion - Frameshift	Central_nervous_system
COSM3765033	c.3611C>T	p.S1204L	Substitution - Missense	Central_nervous_system
COSM292119	c.1489C>A	p.P497T	Substitution - Missense	Large_intestine
COSM1124809	c.2249G>A	p.R750H	Substitution - Missense	Endometrium
COSM1469185	c.252delG	p.L85fs*28	Deletion - Frameshift	Breast
COSM5715829	c.3450C>T	p.N1150N	Substitution - coding silent	Skin
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM4152566	c.491C>T	p.S164F	Substitution - Missense	Kidney
COSM757658	c.1286A>C	p.H429P	Substitution - Missense	Lung
COSM4742913	c.3970C>T	p.R1324W	Substitution - Missense	Small_intestine
COSM4436956	c.3247G>C	p.E1083Q	Substitution - Missense	Oesophagus
COSM4769937	c.1254C>T	p.V418V	Substitution - coding silent	Biliary_tract
COSM1715115	c.1321C>T	p.R441W	Substitution - Missense	Skin
COSM5715829	c.3450C>T	p.N1150N	Substitution - coding silent	Skin
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM4390073	c.721G>T	p.E241*	Substitution - Nonsense	Urinary_tract
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM4950261	c.634_635insG	p.S213fs*2	Insertion - Frameshift	Liver
COSM4110861	c.750A>G	p.K250K	Substitution - coding silent	Stomach
COSM1729897	c.472G>T	p.E158*	Substitution - Nonsense	Liver
COSM1178128	c.974A>G	p.Y325C	Substitution - Missense	Central_nervous_system
COSM4423478	c.397A>G	p.N133D	Substitution - Missense	Central_nervous_system
COSM1469184	c.1364G>T	p.G455V	Substitution - Missense	Large_intestine
COSM4837754	c.1909C>T	p.R637W	Substitution - Missense	Cervix
COSM316700	c.162G>T	p.S54S	Substitution - coding silent	Soft_tissue
COSM1124823	c.24T>C	p.S8S	Substitution - coding silent	Endometrium
COSM2150924	c.2219G>A	p.R740H	Substitution - Missense	Central_nervous_system
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM457977	c.3908A>G	p.Y1303C	Substitution - Missense	Prostate
COSM3973835	c.3222G>T	p.W1074C	Substitution - Missense	Central_nervous_system
COSM385747	c.1903C>G	p.H635D	Substitution - Missense	Lung
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM3670287	c.1648C>T	p.R550C	Substitution - Missense	Large_intestine
COSM1469185	c.252delG	p.L85fs*28	Deletion - Frameshift	Prostate
COSM4742919	c.252_253insG	p.L85fs*4	Insertion - Frameshift	Breast
COSM79112	c.2649C>A	p.C883*	Substitution - Nonsense	Ovary
COSM1270991	c.2174G>A	p.R725H	Substitution - Missense	Stomach
COSM5420997	c.140_143delCCCC	p.P47fs*65	Deletion - Frameshift	Prostate
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM1682715	c.3736C>A	p.P1246T	Substitution - Missense	Large_intestine
COSM3845307	c.2214G>C	p.Q738H	Substitution - Missense	Breast
COSM255663	c.1939C>T	p.R647*	Substitution - Nonsense	Central_nervous_system
COSM5100802	c.1757_1758insG	p.I587fs*17	Insertion - Frameshift	Large_intestine
COSM4765831	c.253_254insG	p.L85fs*4	Insertion - Frameshift	Stomach
COSM4742919	c.252_253insG	p.L85fs*4	Insertion - Frameshift	Large_intestine
COSM3845306	c.3562C>T	p.R1188*	Substitution - Nonsense	Breast
COSM757657	c.1278C>T	p.S426S	Substitution - coding silent	Lung
COSM1124796	c.3827G>T	p.R1276I	Substitution - Missense	Endometrium
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM1124813	c.1831G>C	p.V611L	Substitution - Missense	Endometrium
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM757662	c.3057G>T	p.L1019L	Substitution - coding silent	Lung
COSM1178926	c.143_144insC	p.G49fs*13	Insertion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM1124803	c.3154T>G	p.S1052A	Substitution - Missense	Endometrium
COSM4005163	c.1976G>T	p.G659V	Substitution - Missense	Urinary_tract
COSM4110857	c.3537C>T	p.L1179L	Substitution - coding silent	Stomach
COSM146124	c.3418C>G	p.L1140V	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4950261	c.634_635insG	p.S213fs*2	Insertion - Frameshift	Liver
COSM3800739	c.2827G>A	p.E943K	Substitution - Missense	Urinary_tract
COSM5366928	c.3385C>T	p.R1129*	Substitution - Nonsense	Large_intestine
COSM5693979	c.762A>T	p.V254V	Substitution - coding silent	Soft_tissue
COSM5508241	c.1077G>C	p.E359D	Substitution - Missense	Biliary_tract
COSM1757284	c.1199C>G	p.S400C	Substitution - Missense	Urinary_tract
COSM2153280	c.1409T>C	p.L470P	Substitution - Missense	Central_nervous_system
COSM3694792	c.162G>A	p.S54S	Substitution - coding silent	Large_intestine
COSM5546969	c.591_592delGA	p.E197fs*17	Deletion - Frameshift	Prostate
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM1293058	c.1195C>T	p.Q399*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM316701	c.1178A>T	p.Q393L	Substitution - Missense	Lung
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM3364098	c.1472A>C	p.K491T	Substitution - Missense	Kidney
COSM305337	c.166G>T	p.A56S	Substitution - Missense	Central_nervous_system
COSM5413025	c.1879C>T	p.R627W	Substitution - Missense	Skin
COSM372350	c.2387C>A	p.P796Q	Substitution - Missense	Lung
COSM5813029	c.645C>G	p.P215P	Substitution - coding silent	Liver
COSM307173	c.702G>A	p.P234P	Substitution - coding silent	Central_nervous_system
COSM303614	c.3292delC	p.R1098fs*22	Deletion - Frameshift	Central_nervous_system
COSM1293057	c.3337_3339delTAC	p.Y1113delY	Deletion - In frame	Haematopoietic_and_lymphoid_tissue
COSM5681151	c.1380C>A	p.T460T	Substitution - coding silent	Soft_tissue
COSM488568	c.2269C>A	p.Q757K	Substitution - Missense	Kidney
COSM757660	c.2384C>G	p.T795S	Substitution - Missense	Lung
COSM316699	c.1389G>T	p.G463G	Substitution - coding silent	Lung
COSM4522292	c.1154G>T	p.C385F	Substitution - Missense	Skin
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM5004851	c.1073+4C>T	p.?	Unknown	Haematopoietic_and_lymphoid_tissue
COSM4980593	c.3382G>T	p.E1128*	Substitution - Nonsense	Oesophagus
COSM4828446	c.877C>T	p.R293C	Substitution - Missense	Small_intestine
COSM1132269	c.778+1G>T	p.?	Unknown	Prostate
COSM3737488	c.2229C>A	p.C743*	Substitution - Nonsense	Soft_tissue
COSM1757284	c.1199C>G	p.S400C	Substitution - Missense	Urinary_tract
COSM3670287	c.1648C>T	p.R550C	Substitution - Missense	Central_nervous_system
COSM1472314	c.3886_3887CC>AG	p.P1296S	Substitution - Missense	Prostate
COSM5498463	c.1470+6G>A	p.?	Unknown	Biliary_tract
COSM1270990	c.2350C>G	p.Q784E	Substitution - Missense	Oesophagus
COSM248487	c.2548A>G	p.M850V	Substitution - Missense	Prostate
COSM5910116	c.2412G>A	p.K804K	Substitution - coding silent	Skin
COSM5413024	c.3276T>C	p.F1092F	Substitution - coding silent	Skin
COSM5731903	c.2308delC	p.L770fs*1	Deletion - Frameshift	Pancreas
COSM5437781	c.2454T>C	p.P818P	Substitution - coding silent	Oesophagus
COSM255663	c.1939C>T	p.R647*	Substitution - Nonsense	Stomach
COSM4881556	c.3750C>A	p.T1250T	Substitution - coding silent	Upper_aerodigestive_tract
COSM5419315	c.3631A>G	p.T1211A	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM5557979	c.1038G>C	p.K346N	Substitution - Missense	Prostate
COSM457978	c.3121C>T	p.R1041W	Substitution - Missense	Breast
COSM1124795	c.4018G>A	p.D1340N	Substitution - Missense	Endometrium
COSM1756657	c.3297C>T	p.I1099I	Substitution - coding silent	Urinary_tract
COSM5417986	c.2686-13_2686-2delTTCGTGCCTCCA	p.?	Unknown	Haematopoietic_and_lymphoid_tissue
COSM4742914	c.3492delT	p.F1164fs*9	Deletion - Frameshift	Large_intestine
COSM5497345	c.420_435del16	p.L141fs*5	Deletion - Frameshift	Biliary_tract
COSM5413028	c.908C>T	p.S303F	Substitution - Missense	Skin
COSM3563108	c.2400G>A	p.G800G	Substitution - coding silent	Skin
COSM3406562	c.1288C>A	p.R430R	Substitution - coding silent	Central_nervous_system
COSM4839655	c.46C>A	p.P16T	Substitution - Missense	Cervix
COSM4340380	c.619C>T	p.Q207*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM4830111	c.3912C>T	p.L1304L	Substitution - coding silent	Cervix
COSM4110856	c.3551C>T	p.T1184M	Substitution - Missense	Stomach
COSM316701	c.1178A>T	p.Q393L	Substitution - Missense	Soft_tissue
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM3563105	c.2910G>T	p.L970L	Substitution - coding silent	Skin
COSM1124816	c.1350T>C	p.C450C	Substitution - coding silent	Endometrium
COSM3708718	c.724C>T	p.R242C	Substitution - Missense	Small_intestine
COSM5988913	c.2575G>T	p.E859*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM757661	c.2493G>C	p.K831N	Substitution - Missense	Lung
COSM1756658	c.1253T>G	p.V418G	Substitution - Missense	Urinary_tract
COSM1124817	c.1092G>T	p.K364N	Substitution - Missense	Endometrium
COSM1469185	c.252delG	p.L85fs*28	Deletion - Frameshift	Large_intestine
COSM3682160	c.258C>T	p.L86L	Substitution - coding silent	Haematopoietic_and_lymphoid_tissue
COSM5894190	c.1735C>T	p.Q579*	Substitution - Nonsense	Skin
COSM3563110	c.1938C>T	p.L646L	Substitution - coding silent	Skin
COSM5646109	c.1349G>C	p.C450S	Substitution - Missense	Oesophagus
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM1124802	c.3180C>A	p.T1060T	Substitution - coding silent	Endometrium
COSM3765033	c.3611C>T	p.S1204L	Substitution - Missense	Central_nervous_system
COSM1178926	c.143_144insC	p.G49fs*13	Insertion - Frameshift	Prostate
COSM422498	c.945G>A	p.R315R	Substitution - coding silent	Urinary_tract
COSM1124820	c.558C>T	p.S186S	Substitution - coding silent	Endometrium
COSM4791908	c.2261A>C	p.Q754P	Substitution - Missense	Liver
COSM3563114	c.224G>A	p.G75E	Substitution - Missense	Skin
COSM388318	c.386G>T	p.G129V	Substitution - Missense	Lung
COSM3563111	c.1932G>A	p.E644E	Substitution - coding silent	Skin
COSM3563107	c.2437C>T	p.P813S	Substitution - Missense	Skin
COSM1497337	c.2960A>G	p.N987S	Substitution - Missense	Kidney
COSM1124798	c.3485T>C	p.L1162P	Substitution - Missense	Endometrium
COSM1469185	c.252delG	p.L85fs*28	Deletion - Frameshift	Large_intestine
COSM2150924	c.2219G>A	p.R740H	Substitution - Missense	Central_nervous_system
COSM4167359	c.1279G>A	p.V427M	Substitution - Missense	Breast
COSM757654	c.144T>A	p.P48P	Substitution - coding silent	Lung
COSM3379678	c.1097C>T	p.S366L	Substitution - Missense	Large_intestine
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM1469185	c.252delG	p.L85fs*28	Deletion - Frameshift	Large_intestine
COSM3095621	c.405T>C	p.C135C	Substitution - coding silent	Large_intestine
COSM4970096	c.1258C>A	p.H420N	Substitution - Missense	Central_nervous_system
COSM3973834	c.3313G>A	p.A1105T	Substitution - Missense	Central_nervous_system
COSM1240713	c.1276A>G	p.S426G	Substitution - Missense	Oesophagus
COSM1132271	c.3887C>G	p.P1296R	Substitution - Missense	Prostate
COSM1124799	c.3280+1G>T	p.?	Unknown	Endometrium
COSM1469181	c.2791G>A	p.D931N	Substitution - Missense	Large_intestine
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM242345	c.204_205delAG	p.D69fs*9	Deletion - Frameshift	Prostate
COSM3095603	c.1613G>T	p.G538V	Substitution - Missense	Large_intestine
COSM4110860	c.1235G>A	p.C412Y	Substitution - Missense	Stomach
COSM4889763	c.1864G>T	p.D622Y	Substitution - Missense	Upper_aerodigestive_tract
COSM3563113	c.410C>T	p.P137L	Substitution - Missense	Skin
COSM4983369	c.410C>G	p.P137R	Substitution - Missense	Oesophagus
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM5413027	c.1207C>T	p.P403S	Substitution - Missense	Skin
COSM3095566	c.4071T>A	p.I1357I	Substitution - coding silent	Large_intestine
COSM4110856	c.3551C>T	p.T1184M	Substitution - Missense	Upper_aerodigestive_tract
COSM146125	c.2542G>A	p.V848M	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM255676	c.3595C>G	p.Q1199E	Substitution - Missense	Central_nervous_system
COSM757656	c.481G>A	p.E161K	Substitution - Missense	Lung
COSM2156506	c.2532C>A	p.V844V	Substitution - coding silent	Central_nervous_system
COSM4655147	c.2865T>G	p.L955L	Substitution - coding silent	Large_intestine
COSM5435217	c.727G>A	p.V243I	Substitution - Missense	Oesophagus
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM3379707	c.3502C>G	p.L1168V	Substitution - Missense	Pancreas
COSM1124794	c.4049G>A	p.R1350H	Substitution - Missense	Endometrium
COSM4773570	c.3411T>G	p.Y1137*	Substitution - Nonsense	Stomach
COSM4808384	c.2863C>T	p.L955F	Substitution - Missense	Pancreas
COSM2156506	c.2532C>A	p.V844V	Substitution - coding silent	Central_nervous_system
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM1497338	c.3619G>A	p.V1207I	Substitution - Missense	Kidney
COSM4340433	c.3965C>T	p.P1322L	Substitution - Missense	Bone
COSM4921634	c.2671T>C	p.S891P	Substitution - Missense	Liver
COSM3095571	c.3712C>T	p.R1238W	Substitution - Missense	Large_intestine
COSM5043992	c.3111+1G>C	p.?	Unknown	Liver
COSM457981	c.275C>T	p.P92L	Substitution - Missense	Breast
COSM4742915	c.3004A>G	p.K1002E	Substitution - Missense	Large_intestine
COSM4167359	c.1279G>A	p.V427M	Substitution - Missense	Meninges
COSM5475355	c.3946G>A	p.D1316N	Substitution - Missense	Large_intestine
COSM5900441	c.1160C>T	p.S387F	Substitution - Missense	Skin
COSM1124818	c.699G>A	p.K233K	Substitution - coding silent	Endometrium
COSM255663	c.1939C>T	p.R647*	Substitution - Nonsense	Central_nervous_system
COSM1735242	c.143delC	p.P48fs*65	Deletion - Frameshift	Pancreas
COSM3095571	c.3712C>T	p.R1238W	Substitution - Missense	Large_intestine
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM4110858	c.2383A>T	p.T795S	Substitution - Missense	Stomach
COSM4171962	c.2204G>A	p.W735*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM4806297	c.3593A>T	p.K1198M	Substitution - Missense	Liver
COSM3390769	c.3331C>T	p.L1111F	Substitution - Missense	Pancreas
COSM294974	c.3068A>G	p.E1023G	Substitution - Missense	Large_intestine
COSM1124804	c.3130C>T	p.L1044F	Substitution - Missense	Endometrium
COSM4962090	c.4088G>A	p.R1363H	Substitution - Missense	Pancreas
COSM4828446	c.877C>T	p.R293C	Substitution - Missense	Cervix
COSM4928146	c.1989G>A	p.L663L	Substitution - coding silent	Liver
COSM3095605	c.1575C>T	p.S525S	Substitution - coding silent	Large_intestine
COSM4492840	c.4048C>T	p.R1350C	Substitution - Missense	Skin
COSM1315670	c.754G>A	p.E252K	Substitution - Missense	Urinary_tract
COSM1682715	c.3736C>A	p.P1246T	Substitution - Missense	Large_intestine
COSM1124806	c.2794A>G	p.I932V	Substitution - Missense	Endometrium
COSM303613	c.120C>A	p.A40A	Substitution - coding silent	Central_nervous_system
COSM1293059	c.159delC	p.S54fs*59	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM4791908	c.2261A>C	p.Q754P	Substitution - Missense	Liver
COSM146125	c.2542G>A	p.V848M	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3390770	c.1739G>A	p.R580H	Substitution - Missense	Pancreas
COSM5513819	c.1433G>A	p.R478Q	Substitution - Missense	Biliary_tract
COSM1316858	c.1477A>T	p.T493S	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1756657	c.3297C>T	p.I1099I	Substitution - coding silent	Urinary_tract
COSM1124808	c.2638C>T	p.H880Y	Substitution - Missense	Oesophagus
COSM1124805	c.3011C>A	p.P1004H	Substitution - Missense	Endometrium
COSM1469182	c.2530G>A	p.V844I	Substitution - Missense	Large_intestine
COSM5789573	c.3871A>C	p.N1291H	Substitution - Missense	Breast
COSM4806297	c.3593A>T	p.K1198M	Substitution - Missense	Liver
COSM757659	c.1509C>G	p.T503T	Substitution - coding silent	Lung
COSM3095590	c.2391G>T	p.E797D	Substitution - Missense	Large_intestine
COSM1735242	c.143delC	p.P48fs*65	Deletion - Frameshift	Biliary_tract
COSM5419561	c.2579_2580GG>AA	p.W860*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM5894190	c.1735C>T	p.Q579*	Substitution - Nonsense	Skin
COSM5064853	c.583G>A	p.V195M	Substitution - Missense	Stomach
COSM3845308	c.1172C>T	p.A391V	Substitution - Missense	Breast
COSM457979	c.2041_2044delTACT	p.Y681fs*89	Deletion - Frameshift	Breast
COSM3379678	c.1097C>T	p.S366L	Substitution - Missense	Pancreas
COSM3694704	c.2555C>G	p.S852C	Substitution - Missense	Large_intestine
COSM4835800	c.1338G>C	p.L446L	Substitution - coding silent	Cervix
COSM3965482	c.3312C>T	p.L1104L	Substitution - coding silent	Lung
COSM1178926	c.143_144insC	p.G49fs*13	Insertion - Frameshift	Breast
COSM757655	c.364G>A	p.E122K	Substitution - Missense	Lung
COSM1491237	c.3634C>G	p.L1212V	Substitution - Missense	Breast
COSM4381993	c.1300G>C	p.D434H	Substitution - Missense	Large_intestine
COSM1124822	c.136G>C	p.A46P	Substitution - Missense	Endometrium
COSM1491239	c.3111G>A	p.K1037K	Substitution - coding silent	Breast
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM3973836	c.3080C>G	p.T1027S	Substitution - Missense	Central_nervous_system
COSM5631384	c.2637G>A	p.M879I	Substitution - Missense	Oesophagus
COSM4831808	c.186C>A	p.T62T	Substitution - coding silent	Cervix
COSM1124801	c.3239C>T	p.A1080V	Substitution - Missense	Endometrium
COSM5589420	c.110C>T	p.S37F	Substitution - Missense	Skin
COSM248484	c.3407A>C	p.Y1136S	Substitution - Missense	Prostate
COSM5941155	c.1737+7C>T	p.?	Unknown	Skin
COSM5616360	c.667G>T	p.G223*	Substitution - Nonsense	Lung
COSM1124797	c.3821G>A	p.R1274Q	Substitution - Missense	Endometrium
COSM1315669	c.763G>C	p.D255H	Substitution - Missense	Urinary_tract
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM4110859	c.1695A>C	p.T565T	Substitution - coding silent	Stomach
COSM4888117	c.1445C>A	p.T482K	Substitution - Missense	Upper_aerodigestive_tract
COSM5023333	c.94G>A	p.E32K	Substitution - Missense	Bone
COSM5715829	c.3450C>T	p.N1150N	Substitution - coding silent	Skin
COSM4608193	c.962G>A	p.G321E	Substitution - Missense	Adrenal_gland
COSM1735242	c.143delC	p.P48fs*65	Deletion - Frameshift	Large_intestine
COSM1637772	c.1287C>T	p.H429H	Substitution - coding silent	Bone
COSM4742916	c.2173C>T	p.R725C	Substitution - Missense	Large_intestine
COSM1178128	c.974A>G	p.Y325C	Substitution - Missense	Prostate
COSM4886952	c.1143C>T	p.C381C	Substitution - coding silent	Upper_aerodigestive_tract
COSM1316859	c.1475A>T	p.N492I	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM488569	c.150T>C	p.P50P	Substitution - coding silent	Kidney
COSM1124812	c.1849C>T	p.R617C	Substitution - Missense	Endometrium
COSM5511337	c.3433-1G>A	p.?	Unknown	Biliary_tract
COSM1331711	c.277C>G	p.P93A	Substitution - Missense	Ovary
COSM3563112	c.1385C>T	p.T462I	Substitution - Missense	Skin
COSM5748960	c.2206C>T	p.R736C	Substitution - Missense	Pancreas
COSM3563104	c.3039C>T	p.F1013F	Substitution - coding silent	Skin
COSM5366928	c.3385C>T	p.R1129*	Substitution - Nonsense	Large_intestine
COSM1124814	c.1786A>G	p.S596G	Substitution - Missense	Endometrium
COSM130349	c.2342C>G	p.T781R	Substitution - Missense	Upper_aerodigestive_tract
COSM1491238	c.3483C>T	p.Y1161Y	Substitution - coding silent	Breast
COSM316700	c.162G>T	p.S54S	Substitution - coding silent	Lung
COSM4742918	c.451A>C	p.T151P	Substitution - Missense	Large_intestine
COSM1757283	c.3602G>A	p.G1201E	Substitution - Missense	Urinary_tract
COSM1469185	c.252delG	p.L85fs*28	Deletion - Frameshift	Breast
COSM1469185	c.252delG	p.L85fs*28	Deletion - Frameshift	Large_intestine
COSM1233531	c.1243A>G	p.T415A	Substitution - Missense	Large_intestine
COSM3670287	c.1648C>T	p.R550C	Substitution - Missense	Central_nervous_system
COSM1124811	c.1986G>A	p.L662L	Substitution - coding silent	Endometrium
COSM1132270	c.3886C>A	p.P1296T	Substitution - Missense	Prostate

> Text Mining based Variations

PMID	Variation	Cancer	Evidence
27959900	mutation	Chronic Lymphocytic Leukemia	Mutation frequencies of MYD88, SAMHD1, EGR2, DDX3X, ZMYM3, and MED12 showed similar incidence with Caucasians, while mutation frequencies of ATM, TP53, KLHL6, BCOR and CDKN2A tend to be higher in Koreans than in Caucasians.
27060156	Mutation	Chronic Lymphocytic Leukemia	In contrast, mutations in NOTCH1, SF3B1, POT1, FBXW7, MYD88, NXF1, XPO1, ZMYM3, or CHD2 were predominantly already clonal prior to therapy indicative of a pretreatment pathogenetic driver role in CLL.
25030029	Mutation	Medulloblastoma	The data show gene mutations associated with i17q tumors in previous studies (KMD6A, ZMYM3, MLL3 and GPS2) were correlated with significantly worse outcomes despite not being specific to i17q in this set.
22722829	Mutation	Medulloblastoma	Recurrent mutations were detected in 41 genes not yet implicated in medulloblastoma; several target distinct components of the epigenetic machinery in different disease subgroups, such as regulators of H3K27 and H3K4 trimethylation in subgroups 3 and 4 (for example, KDM6A and ZMYM3), and CTNNB1-associated chromatin re-modellers in WNT-subgroup tumours (for example, SMARCA4 and CREBBP).
22150006	Mutation	Chronic Lymphocytic Leukemia	Nine genes that are mutated at significant frequencies were identified, including four with established roles in chronic lymphocytic leukemia (TP53 in 15% of patients, ATM in 9%, MYD88 in 10%, and NOTCH1 in 4%) and five with unestablished roles (SF3B1, ZMYM3, MAPK1, FBXW7, and DDX3X).
24710217	Mutation	Childhood Malignant Neoplasm	The most frequently mutated genes are H3F3A, PHF6, ATRX, KDM6A, SMARCA4, ASXL2, CREBBP, EZH2, MLL2, USP7, ASXL1, NSD2, SETD2, SMC1A and ZMYM3.

Summary
Symbol	ZMYM3
Name	zinc finger MYM-type containing 3
Aliases	ZNF198L2; DXS6673E; KIAA0385; ZNF261; zinc finger protein 261; XFIM; Zinc finger MYM-type protein 3
Location	Xq13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant
Q14202	267	S	Phosphoserine	-	No	None detected
Q14202	464	S	Phosphoserine	-	No	None detected
Q14202	795	T	Phosphothreonine	-	Yes	p.T795S (cancer: LUSC, STAD)
Q14202	817	T	Phosphothreonine	-	No	None detected
Q14202	826	T	Phosphothreonine	-	No	None detected

Summary
Symbol	ZMYM3
Name	zinc finger MYM-type containing 3
Aliases	ZNF198L2; DXS6673E; KIAA0385; ZNF261; zinc finger protein 261; XFIM; Zinc finger MYM-type protein 3
Location	Xq13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	5.548	5.427	0.069	0.669	NS
BRCA	Breast invasive carcinoma	112	1100	5.671	5.737	0.062	0.198	NS
CESC	Cervical and endocervical cancers	3	306	5.403	5.145	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	4.904	5.405	0.466	9.16e-09	NS
ESCA	Esophageal carcinoma	11	185	5.585	5.574	0.032	0.908	NS
GBM	Glioblastoma multiforme	5	166	6.633	6.099	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	4.921	4.769	-0.145	0.13	NS
KIRC	Kidney renal clear cell carcinoma	72	534	5.87	5.47	-0.398	1.74e-16	NS
KIRP	Kidney renal papillary cell carcinoma	32	291	5.94	5.786	-0.152	0.0355	NS
LAML	Acute Myeloid Leukemia	0	173	NA	7.207	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	6.315	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	4.228	4.712	0.572	4.36e-10	NS
LUAD	Lung adenocarcinoma	59	517	5.499	5.846	0.486	5.67e-11	NS
LUSC	Lung squamous cell carcinoma	51	501	5.403	5.558	0.257	0.00306	NS
OV	Ovarian serous cystadenocarcinoma	0	307	NA	7.024	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	5.551	5.169	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	6.048	5.527	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	5.878	5.885	-0.011	0.884	NS
READ	Rectum adenocarcinoma	10	167	4.995	5.474	0.512	0.00169	NS
SARC	Sarcoma	2	263	5.512	5.501	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	5.601	6.067	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	5.594	5.613	0.188	0.0948	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	6.794	NA	NA	NA
THCA	Thyroid carcinoma	59	509	5.925	6.07	0.185	8.74e-05	NS
THYM	Thymoma	2	120	6.107	6.076	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	5.858	6.101	0.088	0.396	NS

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

Tissue	Expression Level (TPM)
Adipose tissue	7.7
Adrenal gland	18.7
Appendix	11.8
Bone marrow	4.5
Breast	9.1
Cerebral cortex	26.4
Cervix, uterine	15.3
Colon	7
Duodenum	7.4
Endometrium	22.9
Epididymis	22.2
Esophagus	8.7
Fallopian tube	31.3
Gallbladder	15.4
Heart muscle	6.8
Kidney	10
Liver	4.3
Lung	16.5
Lymph node	14.3
Ovary	43.8
Pancreas	1.7
Parathyroid gland	23.3
Placenta	11.2
Prostate	21.5
Rectum	8.7
Salivary gland	5.1
Seminal vesicle	23.6
Skeletal muscle	3.7
Skin	13.5
Small intestine	8.2
Smooth muscle	21.5
Spleen	18.3
Stomach	8.6
Testis	31.4
Thyroid gland	21
Tonsil	10.4
Urinary bladder	10.8

> Text Mining based Expression [ TOP ]
There is no record.

Summary
Symbol	ZMYM3
Name	zinc finger MYM-type containing 3
Aliases	ZNF198L2; DXS6673E; KIAA0385; ZNF261; zinc finger protein 261; XFIM; Zinc finger MYM-type protein 3
Location	Xq13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.205	3.18e-05	20.8	66.3	12.9	Neutral
BRCA	Breast invasive carcinoma	1075	0.107	0.000456	18.1	67.6	14.2	Neutral
CESC	Cervical and endocervical cancers	292	0.171	0.00335	22.3	65.8	12	Neutral
COAD	Colon adenocarcinoma	449	0.011	0.819	12.5	70.8	16.7	Neutral
ESCA	Esophageal carcinoma	183	0.211	0.0041	18	55.2	26.8	Neutral
GBM	Glioblastoma multiforme	147	0.076	0.361	24.5	69.4	6.1	Neutral
HNSC	Head and Neck squamous cell carcinoma	514	0.147	0.00084	15.6	64.8	19.6	Neutral
KIRC	Kidney renal clear cell carcinoma	525	0.038	0.39	9.7	85.9	4.4	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	0.064	0.276	10.4	54.9	34.7	Gain
LAML	Acute Myeloid Leukemia	166	-0.018	0.821	3	95.8	1.2	Neutral
LGG	Brain Lower Grade Glioma	513	-0.022	0.624	12.7	76.6	10.7	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.117	0.025	20.6	61.8	17.6	Neutral
LUAD	Lung adenocarcinoma	512	0.086	0.0527	16.4	70.1	13.5	Neutral
LUSC	Lung squamous cell carcinoma	498	0.06	0.185	25.3	60	14.7	Neutral
OV	Ovarian serous cystadenocarcinoma	300	0.182	0.00156	37.7	32.3	30	Loss
PAAD	Pancreatic adenocarcinoma	177	0.102	0.176	12.4	80.8	6.8	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	-0.137	0.082	29.6	67.3	3.1	Neutral
PRAD	Prostate adenocarcinoma	491	-0.291	5.11e-11	6.3	91.2	2.4	Neutral
READ	Rectum adenocarcinoma	164	0.338	9.31e-06	17.7	62.8	19.5	Neutral
SARC	Sarcoma	255	0.101	0.108	34.5	43.5	22	Loss
SKCM	Skin Cutaneous Melanoma	367	0.025	0.637	24	61.3	14.7	Neutral
STAD	Stomach adenocarcinoma	413	0.16	0.00108	13.6	74.8	11.6	Neutral
TGCT	Testicular Germ Cell Tumors	150	-0.084	0.307	18.7	64.7	16.7	Neutral
THCA	Thyroid carcinoma	497	-0.042	0.351	0.8	97.6	1.6	Neutral
THYM	Thymoma	119	0.119	0.196	5	94.1	0.8	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.1	0.0209	11.4	72.4	16.2	Neutral

Summary
Symbol	ZMYM3
Name	zinc finger MYM-type containing 3
Aliases	ZNF198L2; DXS6673E; KIAA0385; ZNF261; zinc finger protein 261; XFIM; Zinc finger MYM-type protein 3
Location	Xq13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.233	1.32e-06	17	408	-0.005	0.0801	NS/NA
BRCA	Breast invasive carcinoma	-0.157	3.41e-06	83	785	-0.089	4.29e-13	NS/NA
CESC	Cervical and endocervical cancers	-0.359	1.1e-10	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.289	1.95e-07	19	297	0.001	0.764	NS/NA
ESCA	Esophageal carcinoma	-0.263	0.000218	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	0.046	0.718	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.225	1.32e-07	20	522	-0.052	0.895	NS/NA
KIRC	Kidney renal clear cell carcinoma	-0.071	0.187	24	319	0.01	7.53e-05	NS/NA
KIRP	Kidney renal papillary cell carcinoma	-0.004	0.944	23	275	0.002	0.954	NS/NA
LAML	Acute Myeloid Leukemia	-0.093	0.227	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	-0.077	0.0784	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.1	0.0417	41	373	-0.003	0.0349	NS/NA
LUAD	Lung adenocarcinoma	-0.152	0.000883	21	456	0.134	0.212	NS/NA
LUSC	Lung squamous cell carcinoma	-0.173	0.000726	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	-0.45	0.23	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.154	0.0377	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.057	0.441	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.178	3.84e-05	35	498	-0.015	0.64	NS/NA
READ	Rectum adenocarcinoma	-0.209	0.0365	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.123	0.0459	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.163	0.000392	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.291	1.3e-08	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.363	3.83e-06	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.1	0.0186	50	509	-0.005	0.489	NS/NA
THYM	Thymoma	-0.138	0.129	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.293	1.43e-10	34	431	0.149	3.43e-07	NS/NA

Summary
Symbol	ZMYM3
Name	zinc finger MYM-type containing 3
Aliases	ZNF198L2; DXS6673E; KIAA0385; ZNF261; zinc finger protein 261; XFIM; Zinc finger MYM-type protein 3
Location	Xq13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

Tissue	Level	Level Name
Adrenal gland	3	High
Appendix	3	High
Bone marrow	3	High
Breast	3	High
Bronchus	3	High
Caudate	3	High
Cerebellum	3	High
Cerebral cortex	3	High
Cervix, uterine	3	High
Colon	3	High
Duodenum	3	High
Endometrium	3	High
Epididymis	3	High
Esophagus	3	High
Fallopian tube	3	High
Gallbladder	3	High
Heart muscle	3	High
Hippocampus	3	High
Kidney	3	High
Liver	2	Medium
Lung	3	High
Lymph node	3	High
Oral mucosa	3	High
Ovary	3	High
Pancreas	3	High
Parathyroid gland	2	Medium
Placenta	3	High
Prostate	3	High
Rectum	3	High
Salivary gland	3	High
Seminal vesicle	3	High
Skeletal muscle	1	Low
Skin	3	High
Small intestine	3	High
Smooth muscle	3	High
Soft tissue	2	Medium
Spleen	3	High
Stomach	3	High
Testis	3	High
Thyroid gland	3	High
Tonsil	3	High
Urinary bladder	3	High
Vagina	3	High

Summary
Symbol	ZMYM3
Name	zinc finger MYM-type containing 3
Aliases	ZNF198L2; DXS6673E; KIAA0385; ZNF261; zinc finger protein 261; XFIM; Zinc finger MYM-type protein 3
Location	Xq13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.0369	Significant	24476821
BRCA	Breast invasive carcinoma	521	0.00184	Significant	23000897
COAD	Colon adenocarcinoma	149	0.0128	Significant	22810696
GBM	Glioblastoma multiforme	157	0.0069	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	0.000757	Significant	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.349	NS	26536169
LGG	Brain Lower Grade Glioma	513	1.83e-05	Significant	26824661
LUAD	Lung adenocarcinoma	230	0.00427	Significant	25079552
LUSC	Lung squamous cell carcinoma	178	8.29e-05	Significant	22960745
OV	Ovarian serous cystadenocarcinoma	287	1.77e-10	Significant	21720365
PRAD	Prostate adenocarcinoma	333	0.0332	Significant	26544944
READ	Rectum adenocarcinoma	67	0.0415	Significant	22810696
SKCM	Skin Cutaneous Melanoma	315	0.141	NS	26091043
STAD	Stomach adenocarcinoma	277	8.25e-06	Significant	25079317
THCA	Thyroid carcinoma	391	0.221	NS	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	3.11e-10	Significant	23636398

> Overall survival

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	0.679	0.0645	NS
BRCA	Breast invasive carcinoma	1079	1.476	0.106	NS
CESC	Cervical and endocervical cancers	291	1.259	0.498	NS
COAD	Colon adenocarcinoma	439	1.521	0.141	NS
ESCA	Esophageal carcinoma	184	1.048	0.888	NS
GBM	Glioblastoma multiforme	158	0.807	0.406	NS
HNSC	Head and Neck squamous cell carcinoma	518	1.167	0.436	NS
KIRC	Kidney renal clear cell carcinoma	531	1.478	0.0713	NS
KIRP	Kidney renal papillary cell carcinoma	287	1.009	0.981	NS
LAML	Acute Myeloid Leukemia	149	0.789	0.427	NS
LGG	Brain Lower Grade Glioma	511	0.595	0.0388	Longer
LIHC	Liver hepatocellular carcinoma	365	1.219	0.457	NS
LUAD	Lung adenocarcinoma	502	0.761	0.187	NS
LUSC	Lung squamous cell carcinoma	494	0.87	0.474	NS
OV	Ovarian serous cystadenocarcinoma	303	0.927	0.721	NS
PAAD	Pancreatic adenocarcinoma	177	0.666	0.187	NS
PCPG	Pheochromocytoma and Paraganglioma	179	1	1	NS
PRAD	Prostate adenocarcinoma	497	0.329	0.305	NS
READ	Rectum adenocarcinoma	159	1.359	0.541	NS
SARC	Sarcoma	259	2.082	0.0176	Shorter
SKCM	Skin Cutaneous Melanoma	459	1.07	0.728	NS
STAD	Stomach adenocarcinoma	388	0.912	0.694	NS
TGCT	Testicular Germ Cell Tumors	134	0	0.317	NS
THCA	Thyroid carcinoma	500	1.96	0.264	NS
THYM	Thymoma	119	0.337	0.211	NS
UCEC	Uterine Corpus Endometrial Carcinoma	543	1.809	0.0381	Shorter

> Stage

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	-0.153	0.00194	Lower
BRCA	Breast invasive carcinoma	1071	0.008	0.786	NS
CESC	Cervical and endocervical cancers	167	0.05	0.523	NS
COAD	Colon adenocarcinoma	445	0.001	0.98	NS
ESCA	Esophageal carcinoma	162	0.091	0.25	NS
HNSC	Head and Neck squamous cell carcinoma	448	-0.003	0.944	NS
KIRC	Kidney renal clear cell carcinoma	531	-0.016	0.709	NS
KIRP	Kidney renal papillary cell carcinoma	260	0.057	0.364	NS
LIHC	Liver hepatocellular carcinoma	347	0.136	0.0112	Higher
LUAD	Lung adenocarcinoma	507	-0.015	0.733	NS
LUSC	Lung squamous cell carcinoma	497	0.01	0.823	NS
OV	Ovarian serous cystadenocarcinoma	302	-0.087	0.13	NS
PAAD	Pancreatic adenocarcinoma	176	-0.157	0.0372	Lower
READ	Rectum adenocarcinoma	156	-0.035	0.666	NS
SKCM	Skin Cutaneous Melanoma	410	-0.019	0.707	NS
STAD	Stomach adenocarcinoma	392	-0.012	0.81	NS
TGCT	Testicular Germ Cell Tumors	81	0.204	0.0672	NS
THCA	Thyroid carcinoma	499	0.033	0.463	NS
UCEC	Uterine Corpus Endometrial Carcinoma	501	0.095	0.0332	Higher

> Grade

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	0.068	0.267	NS
HNSC	Head and Neck squamous cell carcinoma	498	0.208	2.75e-06	Higher
KIRC	Kidney renal clear cell carcinoma	525	0.012	0.784	NS
LGG	Brain Lower Grade Glioma	514	-0.108	0.0142	Lower
LIHC	Liver hepatocellular carcinoma	366	0.156	0.00274	Higher
OV	Ovarian serous cystadenocarcinoma	296	0.094	0.107	NS
PAAD	Pancreatic adenocarcinoma	176	0.037	0.622	NS
STAD	Stomach adenocarcinoma	406	-0.028	0.577	NS
UCEC	Uterine Corpus Endometrial Carcinoma	534	0.307	3.87e-13	Higher

Summary
Symbol	ZMYM3
Name	zinc finger MYM-type containing 3
Aliases	ZNF198L2; DXS6673E; KIAA0385; ZNF261; zinc finger protein 261; XFIM; Zinc finger MYM-type protein 3
Location	Xq13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	ZMYM3
Name	zinc finger MYM-type containing 3
Aliases	ZNF198L2; DXS6673E; KIAA0385; ZNF261; zinc finger protein 261; XFIM; Zinc finger MYM-type protein 3
Location	Xq13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for ZMYM3.

Summary
Symbol	ZMYM3
Name	zinc finger MYM-type containing 3
Aliases	ZNF198L2; DXS6673E; KIAA0385; ZNF261; zinc finger protein 261; XFIM; Zinc finger MYM-type protein 3
Location	Xq13.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining [ TOP ]
There is no record for ZMYM3.