CR2Cancer

Summary
Symbol	ZMYND8
Name	zinc finger MYND-type containing 8
Aliases	RACK7; PRKCBP1; protein kinase C binding protein 1; PRO2893; CTCL tumor antigen se14-3; cutaneous T-cell lym ......
Location	20q13.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

[ TOP ]

Domain

PF00439 Bromodomain
PF12064 Domain of unknown function (DUF3544)
PF00855 PWWP domain

Function

May act as a transcriptional corepressor for KDM5D. Required for KDM5D-mediated down-regulation of diverse metastasis-associated genes; the function seems to involve the recognition of the dual histone signature H3K4me1-H3K14ac. Suppresses prostate cancer cell invasion.

Classification

Class	Modification	Substrate	Product	PubMed
Histone modification erase cofactor	Histone acetylation	#	#	25123934

> Gene Ontology [ TOP ]
Biological Process	GO:0001941 postsynaptic membrane organization GO:0010720 positive regulation of cell development GO:0010975 regulation of neuron projection development GO:0010976 positive regulation of neuron projection development GO:0016358 dendrite development GO:0030031 cell projection assembly GO:0031346 positive regulation of cell projection organization GO:0042391 regulation of membrane potential GO:0043954 cellular component maintenance GO:0044089 positive regulation of cellular component biogenesis GO:0045666 positive regulation of neuron differentiation GO:0046847 filopodium assembly GO:0050769 positive regulation of neurogenesis GO:0050773 regulation of dendrite development GO:0050803 regulation of synapse structure or activity GO:0050804 modulation of synaptic transmission GO:0050807 regulation of synapse organization GO:0050808 synapse organization GO:0051489 regulation of filopodium assembly GO:0051491 positive regulation of filopodium assembly GO:0051962 positive regulation of nervous system development GO:0060078 regulation of postsynaptic membrane potential GO:0060079 excitatory postsynaptic potential GO:0060491 regulation of cell projection assembly GO:0060996 dendritic spine development GO:0060998 regulation of dendritic spine development GO:0060999 positive regulation of dendritic spine development GO:0072657 protein localization to membrane GO:0097061 dendritic spine organization GO:0097062 dendritic spine maintenance GO:0097119 postsynaptic density protein 95 clustering GO:0098815 modulation of excitatory postsynaptic potential GO:0099565 chemical synaptic transmission, postsynaptic GO:1900006 positive regulation of dendrite development GO:1901626 regulation of postsynaptic membrane organization GO:1902897 regulation of postsynaptic density protein 95 clustering GO:1902950 regulation of dendritic spine maintenance GO:1902952 positive regulation of dendritic spine maintenance
Molecular Function	GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding GO:0001104 RNA polymerase II transcription cofactor activity GO:0001106 RNA polymerase II transcription corepressor activity GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding GO:0003682 chromatin binding GO:0003714 transcription corepressor activity GO:0008134 transcription factor binding GO:0042393 histone binding GO:0047485 protein N-terminus binding GO:0070491 repressing transcription factor binding
Cellular Component	GO:0030425 dendrite GO:0043197 dendritic spine GO:0043198 dendritic shaft GO:0044309 neuron spine GO:0098794 postsynapse

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	-

Summary
Symbol	ZMYND8
Name	zinc finger MYND-type containing 8
Aliases	RACK7; PRKCBP1; protein kinase C binding protein 1; PRO2893; CTCL tumor antigen se14-3; cutaneous T-cell lym ......
Location	20q13.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]
There is no record.

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM1027511	c.3515G>A	p.S1172N	Substitution - Missense	Endometrium
COSM4596701	c.3293C>T	p.S1098F	Substitution - Missense	Upper_aerodigestive_tract
COSM3547355	c.1826C>T	p.S609L	Substitution - Missense	Skin
COSM3294965	c.588C>T	p.P196P	Substitution - coding silent	Large_intestine
COSM5707467	c.1232T>G	p.I411R	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM25203	c.1314G>A	p.G438G	Substitution - coding silent	Skin
COSM3799615	c.1264G>C	p.D422H	Substitution - Missense	Urinary_tract
COSM255035	c.1175A>C	p.N392T	Substitution - Missense	Urinary_tract
COSM255036	c.1693C>T	p.L565F	Substitution - Missense	Breast
COSM3294965	c.588C>T	p.P196P	Substitution - coding silent	Large_intestine
COSM1665123	c.1664C>A	p.S555*	Substitution - Nonsense	Kidney
COSM1615687	c.3306G>T	p.E1102D	Substitution - Missense	Liver
COSM3770824	c.3119-9T>C	p.?	Unknown	Pancreas
COSM255037	c.469G>C	p.E157Q	Substitution - Missense	Urinary_tract
COSM3911512	c.3527T>G	p.L1176R	Substitution - Missense	Skin
COSM1027530	c.978A>G	p.R326R	Substitution - coding silent	Endometrium
COSM5392260	c.1254G>A	p.K418K	Substitution - coding silent	Skin
COSM1027512	c.3441G>A	p.R1147R	Substitution - coding silent	Endometrium
COSM1027534	c.254C>T	p.P85L	Substitution - Missense	Endometrium
COSM5660057	c.162G>C	p.P54P	Substitution - coding silent	Soft_tissue
COSM242348	c.134C>T	p.P45L	Substitution - Missense	Prostate
COSM253895	c.2074G>C	p.E692Q	Substitution - Missense	Urinary_tract
COSM4927679	c.621A>G	p.E207E	Substitution - coding silent	Liver
COSM3785411	c.1578G>A	p.T526T	Substitution - coding silent	Pancreas
COSM724360	c.1474A>G	p.S492G	Substitution - Missense	Lung
COSM6004419	c.3122C>T	p.T1041I	Substitution - Missense	Prostate
COSM1271002	c.3127C>T	p.P1043S	Substitution - Missense	Oesophagus
COSM4099068	c.2415C>T	p.V805V	Substitution - coding silent	Stomach
COSM5176403	c.3007G>A	p.A1003T	Substitution - Missense	Prostate
COSM5595599	c.2162T>A	p.V721D	Substitution - Missense	Skin
COSM724356	c.69C>T	p.I23I	Substitution - coding silent	Lung
COSM5923373	c.1391C>T	p.S464F	Substitution - Missense	Skin
COSM1233566	c.1391C>G	p.S464C	Substitution - Missense	Large_intestine
COSM3294832	c.2934C>T	p.I978I	Substitution - coding silent	Skin
COSM1233563	c.3033T>G	p.F1011L	Substitution - Missense	Large_intestine
COSM255036	c.1693C>T	p.L565F	Substitution - Missense	Urinary_tract
COSM4634541	c.2512G>A	p.V838M	Substitution - Missense	Large_intestine
COSM1027531	c.853A>G	p.K285E	Substitution - Missense	Endometrium
COSM1641364	c.1964delA	p.K655fs*14	Deletion - Frameshift	Large_intestine
COSM189262	c.2564C>T	p.T855M	Substitution - Missense	Large_intestine
COSM5571886	c.2457G>A	p.V819V	Substitution - coding silent	Prostate
COSM3841207	c.2645C>T	p.S882L	Substitution - Missense	Breast
COSM1027515	c.2860G>A	p.E954K	Substitution - Missense	Breast
COSM5646808	c.40G>A	p.E14K	Substitution - Missense	Oesophagus
COSM1713608	c.556A>C	p.K186Q	Substitution - Missense	Skin
COSM1027524	c.1774+2T>C	p.?	Unknown	Endometrium
COSM278226	c.2194G>A	p.E732K	Substitution - Missense	Large_intestine
COSM4099083	c.974C>T	p.A325V	Substitution - Missense	Stomach
COSM4403583	c.2337A>C	p.E779D	Substitution - Missense	Skin
COSM4747131	c.3034delT	p.Y1012fs*22	Deletion - Frameshift	Stomach
COSM211536	c.104G>C	p.R35T	Substitution - Missense	Upper_aerodigestive_tract
COSM1684621	c.1312delG	p.G439fs*16	Deletion - Frameshift	Large_intestine
COSM724357	c.1215C>T	p.S405S	Substitution - coding silent	Lung
COSM4136941	c.1480+3C>T	p.?	Unknown	Ovary
COSM5034919	c.100G>A	p.E34K	Substitution - Missense	Oesophagus
COSM5568866	c.2525C>G	p.S842*	Substitution - Nonsense	Prostate
COSM1027513	c.3197G>A	p.S1066N	Substitution - Missense	Endometrium
COSM3294913	c.1709G>A	p.R570H	Substitution - Missense	Large_intestine
COSM1615687	c.3306G>T	p.E1102D	Substitution - Missense	Liver
COSM724359	c.1437C>A	p.F479L	Substitution - Missense	Lung
COSM1027514	c.3195G>A	p.S1065S	Substitution - coding silent	Endometrium
COSM1027535	c.159G>A	p.S53S	Substitution - coding silent	Endometrium
COSM6004596	c.2800-4C>A	p.?	Unknown	Prostate
COSM3547347	c.3177C>T	p.S1059S	Substitution - coding silent	Skin
COSM5644689	c.2662C>T	p.P888S	Substitution - Missense	Oesophagus
COSM1027515	c.2860G>A	p.E954K	Substitution - Missense	Large_intestine
COSM1641364	c.1964delA	p.K655fs*14	Deletion - Frameshift	Stomach
COSM1027515	c.2860G>A	p.E954K	Substitution - Missense	Breast
COSM1326698	c.1510G>A	p.A504T	Substitution - Missense	Ovary
COSM3939385	c.2643C>G	p.S881S	Substitution - coding silent	Oesophagus
COSM5037164	c.478G>A	p.E160K	Substitution - Missense	Oesophagus
COSM3841209	c.1542C>G	p.F514L	Substitution - Missense	Breast
COSM4099070	c.2230C>T	p.R744W	Substitution - Missense	Stomach
COSM1027525	c.1718G>A	p.R573H	Substitution - Missense	Endometrium
COSM255036	c.1693C>T	p.L565F	Substitution - Missense	Urinary_tract
COSM5577218	c.2429C>T	p.P810L	Substitution - Missense	Skin
COSM248491	c.3164C>T	p.T1055I	Substitution - Missense	Prostate
COSM4581854	c.2191A>G	p.S731G	Substitution - Missense	Bone
COSM3693550	c.1385C>T	p.T462M	Substitution - Missense	Large_intestine
COSM5013612	c.1933A>T	p.M645L	Substitution - Missense	Kidney
COSM3707811	c.1879G>A	p.E627K	Substitution - Missense	Liver
COSM5366107	c.3249G>A	p.T1083T	Substitution - coding silent	Large_intestine
COSM255036	c.1693C>T	p.L565F	Substitution - Missense	Urinary_tract
COSM5761703	c.1306C>T	p.L436L	Substitution - coding silent	Pancreas
COSM1412230	c.3309G>A	p.T1103T	Substitution - coding silent	Large_intestine
COSM3547349	c.3045G>A	p.W1015*	Substitution - Nonsense	Skin
COSM1412243	c.1120C>T	p.R374C	Substitution - Missense	Large_intestine
COSM3547353	c.1996G>A	p.E666K	Substitution - Missense	Skin
COSM5626801	c.3420C>T	p.P1140P	Substitution - coding silent	Oesophagus
COSM3294850	c.2601G>A	p.S867S	Substitution - coding silent	Biliary_tract
COSM4099081	c.1442C>T	p.A481V	Substitution - Missense	Stomach
COSM278226	c.2194G>A	p.E732K	Substitution - Missense	Stomach
COSM3294975	c.420A>G	p.E140E	Substitution - coding silent	Upper_aerodigestive_tract
COSM4742990	c.788A>G	p.K263R	Substitution - Missense	Large_intestine
COSM3693548	c.3280-1G>C	p.?	Unknown	Large_intestine
COSM3547367	c.304C>T	p.P102S	Substitution - Missense	Skin
COSM253894	c.2140G>C	p.D714H	Substitution - Missense	Urinary_tract
COSM1233562	c.1216G>A	p.A406T	Substitution - Missense	Large_intestine
COSM1027517	c.2692G>A	p.A898T	Substitution - Missense	Large_intestine
COSM4596701	c.3293C>T	p.S1098F	Substitution - Missense	Upper_aerodigestive_tract
COSM4754233	c.3469G>T	p.D1157Y	Substitution - Missense	Stomach
COSM292120	c.1387G>T	p.G463C	Substitution - Missense	Large_intestine
COSM255037	c.469G>C	p.E157Q	Substitution - Missense	Urinary_tract
COSM3294915	c.1691C>A	p.P564H	Substitution - Missense	Large_intestine
COSM3724842	c.838C>G	p.L280V	Substitution - Missense	Lung
COSM4961310	c.2898G>A	p.M966I	Substitution - Missense	Liver
COSM3294828	c.2975C>T	p.A992V	Substitution - Missense	Large_intestine
COSM4391851	c.2312C>T	p.T771M	Substitution - Missense	Prostate
COSM5805446	c.3393A>T	p.T1131T	Substitution - coding silent	Liver
COSM4771082	c.1037A>G	p.K346R	Substitution - Missense	Pleura
COSM3423698	c.3449A>C	p.K1150T	Substitution - Missense	Large_intestine
COSM316706	c.679T>A	p.Y227N	Substitution - Missense	Soft_tissue
COSM3294907	c.1811T>C	p.V604A	Substitution - Missense	Stomach
COSM1179560	c.3498T>C	p.D1166D	Substitution - coding silent	Prostate
COSM3294891	c.2025C>T	p.S675S	Substitution - coding silent	Upper_aerodigestive_tract
COSM1307483	c.1989G>C	p.E663D	Substitution - Missense	Urinary_tract
COSM4742979	c.3080C>T	p.A1027V	Substitution - Missense	Large_intestine
COSM1233565	c.322G>T	p.D108Y	Substitution - Missense	Large_intestine
COSM3547357	c.1624C>T	p.R542*	Substitution - Nonsense	Skin
COSM3939383	c.3194C>T	p.S1065L	Substitution - Missense	Oesophagus
COSM211536	c.104G>C	p.R35T	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4099064	c.2472G>A	p.P824P	Substitution - coding silent	Stomach
COSM5648766	c.1491C>G	p.A497A	Substitution - coding silent	Oesophagus
COSM5016661	c.3119-2_3119delAGC	p.?	Unknown	Kidney
COSM1271003	c.393C>A	p.H131Q	Substitution - Missense	Oesophagus
COSM4742992	c.231G>A	p.E77E	Substitution - coding silent	Large_intestine
COSM1027534	c.254C>T	p.P85L	Substitution - Missense	Skin
COSM3294919	c.1597G>A	p.G533S	Substitution - Missense	Large_intestine
COSM5916859	c.1808C>T	p.A603V	Substitution - Missense	Skin
COSM255037	c.469G>C	p.E157Q	Substitution - Missense	Cervix
COSM5429200	c.620A>C	p.E207A	Substitution - Missense	Oesophagus
COSM443948	c.2435C>T	p.P812L	Substitution - Missense	Breast
COSM5151012	c.1664C>T	p.S555L	Substitution - Missense	Skin
COSM1027521	c.2206G>T	p.D736Y	Substitution - Missense	Endometrium
COSM3371705	c.1524C>T	p.S508S	Substitution - coding silent	Thyroid
COSM419361	c.469G>A	p.E157K	Substitution - Missense	Urinary_tract
COSM5423687	c.2353C>T	p.R785C	Substitution - Missense	Prostate
COSM4099056	c.3141G>A	p.A1047A	Substitution - coding silent	Stomach
COSM1615689	c.2638G>A	p.V880M	Substitution - Missense	Liver
COSM1615687	c.3306G>T	p.E1102D	Substitution - Missense	Prostate
COSM3379069	c.3486G>A	p.S1162S	Substitution - coding silent	Pancreas
COSM6004417	c.3228C>T	p.S1076S	Substitution - coding silent	Prostate
COSM5750324	c.1279C>A	p.P427T	Substitution - Missense	Stomach
COSM1233564	c.3545G>A	p.R1182Q	Substitution - Missense	Large_intestine
COSM5343618	c.255G>A	p.P85P	Substitution - coding silent	Large_intestine
COSM4099060	c.2972A>G	p.Q991R	Substitution - Missense	Stomach
COSM2153238	c.3393_3395delAGA	p.D1132delD	Deletion - In frame	Central_nervous_system
COSM3749714	c.774G>A	p.A258A	Substitution - coding silent	Large_intestine
COSM3547361	c.749-1G>A	p.?	Unknown	Skin
COSM3294868	c.2411C>T	p.T804M	Substitution - Missense	Large_intestine
COSM724361	c.1480G>T	p.A494S	Substitution - Missense	Lung
COSM3294859	c.2481G>A	p.P827P	Substitution - coding silent	Breast
COSM3547359	c.1334C>T	p.S445F	Substitution - Missense	Skin
COSM5605401	c.1798G>A	p.V600I	Substitution - Missense	Skin
COSM4954248	c.790A>G	p.I264V	Substitution - Missense	Liver
COSM350211	c.848G>T	p.C283F	Substitution - Missense	Lung
COSM135884	c.2335G>A	p.E779K	Substitution - Missense	Skin
COSM253896	c.2028G>A	p.E676E	Substitution - coding silent	Urinary_tract
COSM1027515	c.2860G>A	p.E954K	Substitution - Missense	Endometrium
COSM5805448	c.2443A>T	p.T815S	Substitution - Missense	Liver
COSM1641364	c.1964delA	p.K655fs*14	Deletion - Frameshift	Biliary_tract
COSM1027533	c.450T>C	p.C150C	Substitution - coding silent	Endometrium
COSM4405271	c.2705A>T	p.K902M	Substitution - Missense	Skin
COSM3799617	c.840A>G	p.L280L	Substitution - coding silent	Urinary_tract
COSM4099077	c.1652A>T	p.E551V	Substitution - Missense	Stomach
COSM4136943	c.261C>T	p.Y87Y	Substitution - coding silent	Ovary
COSM3911514	c.2299C>T	p.P767S	Substitution - Missense	Skin
COSM3294987	c.312T>C	p.D104D	Substitution - coding silent	Upper_aerodigestive_tract
COSM4961310	c.2898G>A	p.M966I	Substitution - Missense	Liver
COSM1641364	c.1964delA	p.K655fs*14	Deletion - Frameshift	Large_intestine
COSM4001922	c.2315T>C	p.V772A	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM3294899	c.1873G>T	p.D625Y	Substitution - Missense	Large_intestine
COSM4099087	c.853A>C	p.K285Q	Substitution - Missense	Stomach
COSM1190278	c.1805C>T	p.T602M	Substitution - Missense	Lung
COSM5649628	c.661-1G>T	p.?	Unknown	Oesophagus
COSM1495070	c.1348C>T	p.P450S	Substitution - Missense	Kidney
COSM4099079	c.1503G>A	p.T501T	Substitution - coding silent	Stomach
COSM1027515	c.2860G>A	p.E954K	Substitution - Missense	Breast
COSM5891210	c.3424C>T	p.Q1142*	Substitution - Nonsense	Skin
COSM6004419	c.3122C>T	p.T1041I	Substitution - Missense	Prostate
COSM1641364	c.1964delA	p.K655fs*14	Deletion - Frameshift	Large_intestine
COSM5769064	c.568-9C>G	p.?	Unknown	Breast
COSM1027522	c.1952C>T	p.A651V	Substitution - Missense	Endometrium
COSM1615689	c.2638G>A	p.V880M	Substitution - Missense	Liver
COSM1412242	c.1218C>T	p.A406A	Substitution - coding silent	Large_intestine
COSM1713606	c.655G>T	p.E219*	Substitution - Nonsense	Skin
COSM3911514	c.2299C>T	p.P767S	Substitution - Missense	Skin
COSM1641364	c.1964delA	p.K655fs*14	Deletion - Frameshift	Large_intestine
COSM1027514	c.3195G>A	p.S1065S	Substitution - coding silent	Skin
COSM1233561	c.1124G>T	p.R375M	Substitution - Missense	Large_intestine
COSM253894	c.2140G>C	p.D714H	Substitution - Missense	Urinary_tract
COSM1412232	c.3011A>T	p.N1004I	Substitution - Missense	Large_intestine
COSM1027515	c.2860G>A	p.E954K	Substitution - Missense	Cervix
COSM4417043	c.1324C>T	p.R442C	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM4954248	c.790A>G	p.I264V	Substitution - Missense	Liver
COSM3547363	c.524C>T	p.S175F	Substitution - Missense	Skin
COSM1027527	c.1660G>A	p.E554K	Substitution - Missense	Endometrium
COSM316705	c.77G>C	p.R26P	Substitution - Missense	Soft_tissue
COSM4503094	c.630C>T	p.F210F	Substitution - coding silent	Skin
COSM4164742	c.1512A>G	p.A504A	Substitution - coding silent	Kidney
COSM81940	c.1491C>T	p.A497A	Substitution - coding silent	Ovary
COSM4099085	c.872G>A	p.C291Y	Substitution - Missense	Stomach
COSM286729	c.2121G>T	p.K707N	Substitution - Missense	Large_intestine
COSM4620395	c.2927G>A	p.R976Q	Substitution - Missense	Large_intestine
COSM3799619	c.407G>T	p.R136I	Substitution - Missense	Urinary_tract
COSM4482152	c.2578C>T	p.L860L	Substitution - coding silent	Skin
COSM3294909	c.1755G>T	p.E585D	Substitution - Missense	Large_intestine
COSM4001922	c.2315T>C	p.V772A	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1027528	c.1532C>T	p.P511L	Substitution - Missense	Endometrium
COSM478240	c.2992A>G	p.K998E	Substitution - Missense	Kidney
COSM4099081	c.1442C>T	p.A481V	Substitution - Missense	Stomach
COSM5468990	c.2878+10G>A	p.?	Unknown	Large_intestine
COSM316706	c.679T>A	p.Y227N	Substitution - Missense	Lung
COSM3770826	c.2013G>C	p.T671T	Substitution - coding silent	Pancreas
COSM4742986	c.1982delC	p.P661fs*8	Deletion - Frameshift	Large_intestine
COSM3294887	c.2140G>T	p.D714Y	Substitution - Missense	Large_intestine
COSM3294939	c.1316delG	p.G439fs*16	Deletion - Frameshift	Large_intestine
COSM4742982	c.2354G>A	p.R785H	Substitution - Missense	Large_intestine
COSM1615687	c.3306G>T	p.E1102D	Substitution - Missense	Liver
COSM4540845	c.28G>A	p.E10K	Substitution - Missense	Skin
COSM221041	c.1687G>C	p.V563L	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5552499	c.2219A>G	p.D740G	Substitution - Missense	Prostate
COSM1713604	c.2329_2330CC>TT	p.P777F	Substitution - Missense	Skin
COSM1027532	c.589G>A	p.V197I	Substitution - Missense	Endometrium
COSM4742984	c.2013G>A	p.T671T	Substitution - coding silent	Large_intestine
COSM1196473	c.2423C>T	p.T808M	Substitution - Missense	Lung
COSM4951616	c.1053T>A	p.S351S	Substitution - coding silent	Liver
COSM724362	c.2568C>A	p.S856S	Substitution - coding silent	Lung
COSM1178183	c.1938C>A	p.D646E	Substitution - Missense	Prostate
COSM4099073	c.1800C>G	p.V600V	Substitution - coding silent	Stomach
COSM25188	c.2227G>A	p.G743R	Substitution - Missense	Urinary_tract
COSM1027526	c.1718G>C	p.R573P	Substitution - Missense	Endometrium
COSM3953067	c.2800-3C>T	p.?	Unknown	Haematopoietic_and_lymphoid_tissue
COSM3911514	c.2299C>T	p.P767S	Substitution - Missense	Skin
COSM3294905	c.1822G>A	p.D608N	Substitution - Missense	Pancreas
COSM6004596	c.2800-4C>A	p.?	Unknown	Prostate
COSM4099066	c.2439C>T	p.A813A	Substitution - coding silent	Stomach
COSM478242	c.379C>A	p.P127T	Substitution - Missense	Kidney
COSM3963629	c.3431-3C>T	p.?	Unknown	Lung
COSM39217	c.2162T>G	p.V721G	Substitution - Missense	Central_nervous_system
COSM211536	c.104G>C	p.R35T	Substitution - Missense	Upper_aerodigestive_tract
COSM3707811	c.1879G>A	p.E627K	Substitution - Missense	Liver
COSM4434767	c.2218G>C	p.D740H	Substitution - Missense	Oesophagus
COSM316705	c.77G>C	p.R26P	Substitution - Missense	Lung
COSM4742988	c.1261T>A	p.F421I	Substitution - Missense	Large_intestine
COSM4099062	c.2891C>T	p.A964V	Substitution - Missense	Stomach
COSM6004417	c.3228C>T	p.S1076S	Substitution - coding silent	Prostate
COSM189262	c.2564C>T	p.T855M	Substitution - Missense	Stomach
COSM4164740	c.2281G>T	p.D761Y	Substitution - Missense	Kidney
COSM253896	c.2028G>A	p.E676E	Substitution - coding silent	Urinary_tract
COSM3294848	c.2651A>G	p.N884S	Substitution - Missense	Prostate
COSM3294962	c.648T>C	p.C216C	Substitution - coding silent	Large_intestine
COSM3294864	c.2433C>T	p.A811A	Substitution - coding silent	Skin
COSM1027518	c.2668G>A	p.A890T	Substitution - Missense	Endometrium
COSM1027520	c.2440G>A	p.A814T	Substitution - Missense	Endometrium
COSM4564660	c.1334_1335CC>TT	p.S445F	Substitution - Missense	Skin
COSM255035	c.1175A>C	p.N392T	Substitution - Missense	Urinary_tract
COSM4951616	c.1053T>A	p.S351S	Substitution - coding silent	Liver
COSM1027529	c.998G>T	p.R333M	Substitution - Missense	Endometrium
COSM1641364	c.1964delA	p.K655fs*14	Deletion - Frameshift	Prostate
COSM5550598	c.2492C>T	p.A831V	Substitution - Missense	Prostate
COSM1307480	c.3186G>T	p.G1062G	Substitution - coding silent	Urinary_tract
COSM3294965	c.588C>T	p.P196P	Substitution - coding silent	Large_intestine
COSM1412239	c.1341G>A	p.S447S	Substitution - coding silent	Large_intestine
COSM1412229	c.3420delC	p.A1141fs*>48	Deletion - Frameshift	Large_intestine
COSM6004417	c.3228C>T	p.S1076S	Substitution - coding silent	Prostate
COSM4428229	c.375C>G	p.L125L	Substitution - coding silent	Oesophagus
COSM3294866	c.2418C>T	p.T806T	Substitution - coding silent	Skin
COSM5784956	c.1108G>A	p.V370M	Substitution - Missense	Breast
COSM1196473	c.2423C>T	p.T808M	Substitution - Missense	Lung
COSM40504	c.2176G>A	p.D726N	Substitution - Missense	Central_nervous_system
COSM5392258	c.1405G>A	p.D469N	Substitution - Missense	Skin
COSM4773885	c.883_884delAG	p.S295fs*24	Deletion - Frameshift	Stomach
COSM1717671	c.2373delC	p.A792fs*28	Deletion - Frameshift	Haematopoietic_and_lymphoid_tissue
COSM4099058	c.3108C>A	p.C1036*	Substitution - Nonsense	Stomach
COSM248492	c.1173C>T	p.P391P	Substitution - coding silent	Prostate
COSM1412231	c.3026C>T	p.A1009V	Substitution - Missense	Large_intestine
COSM1412236	c.2097A>C	p.A699A	Substitution - coding silent	Large_intestine
COSM253895	c.2074G>C	p.E692Q	Substitution - Missense	Urinary_tract
COSM3547351	c.2155C>T	p.P719S	Substitution - Missense	Skin
COSM4099075	c.1677G>A	p.Q559Q	Substitution - coding silent	Stomach
COSM1027523	c.1914G>T	p.E638D	Substitution - Missense	Endometrium
COSM3294809	c.3531C>T	p.L1177L	Substitution - coding silent	Breast
COSM3841211	c.119G>T	p.R40I	Substitution - Missense	Breast
COSM1307484	c.80C>T	p.S27F	Substitution - Missense	Urinary_tract
COSM5392262	c.556A>G	p.K186E	Substitution - Missense	Skin
COSM1713602	c.3104C>T	p.S1035F	Substitution - Missense	Skin
COSM3294987	c.312T>C	p.D104D	Substitution - coding silent	Upper_aerodigestive_tract
COSM4817009	c.2983G>A	p.E995K	Substitution - Missense	Cervix
COSM5883584	c.1090C>A	p.Q364K	Substitution - Missense	Large_intestine
COSM5755594	c.725A>C	p.H242P	Substitution - Missense	Large_intestine
COSM1495070	c.1348C>T	p.P450S	Substitution - Missense	Kidney
COSM1641364	c.1964delA	p.K655fs*14	Deletion - Frameshift	Large_intestine
COSM1307481	c.3130C>T	p.Q1044*	Substitution - Nonsense	Urinary_tract
COSM1307482	c.3055T>C	p.Y1019H	Substitution - Missense	Urinary_tract
COSM1412231	c.3026C>T	p.A1009V	Substitution - Missense	Large_intestine
COSM1632328	c.3165A>T	p.T1055T	Substitution - coding silent	Liver
COSM1027517	c.2692G>A	p.A898T	Substitution - Missense	Endometrium
COSM1412238	c.2008delA	p.S670fs*37	Deletion - Frameshift	Large_intestine
COSM478241	c.1349C>T	p.P450L	Substitution - Missense	Kidney
COSM3379069	c.3486G>A	p.S1162S	Substitution - coding silent	Pancreas
COSM4442908	c.2470C>T	p.P824S	Substitution - Missense	Large_intestine
COSM1412235	c.2119A>C	p.K707Q	Substitution - Missense	Large_intestine
COSM1565742	c.3181C>T	p.Q1061*	Substitution - Nonsense	Large_intestine
COSM4779861	c.234G>A	p.Q78Q	Substitution - coding silent	Liver
COSM225794	c.173C>T	p.S58L	Substitution - Missense	Skin
COSM1027516	c.2718+2T>C	p.?	Unknown	Endometrium
COSM5057373	c.2333delC	p.P778fs*42	Deletion - Frameshift	Stomach
COSM1027519	c.2544G>T	p.E848D	Substitution - Missense	Endometrium
COSM5501683	c.2188G>A	p.E730K	Substitution - Missense	Biliary_tract
COSM3547365	c.343C>T	p.H115Y	Substitution - Missense	Skin
COSM6004417	c.3228C>T	p.S1076S	Substitution - coding silent	Prostate
COSM4477453	c.2154C>T	p.S718S	Substitution - coding silent	Skin

> Text Mining based Variations

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PMID	Variation	Cancer	Evidence
11888892	Mutation	Colorectal Carcinoma	Examination of 29 previously untested coding polyadenines revealed widespread mutations in MMR-deficient colorectal cancers, with the highest frequencies in ERCC5, CASP8AP2, p72, RAD50, CDC25, RECQL1, CBF2, RACK7, GRK4, and DNAPK (range, 10-33%).
23667654	Mutation	Acute Erythroid Leukemia	A ZMYND8-RELA fusion was ranked first.

Summary
Symbol	ZMYND8
Name	zinc finger MYND-type containing 8
Aliases	RACK7; PRKCBP1; protein kinase C binding protein 1; PRO2893; CTCL tumor antigen se14-3; cutaneous T-cell lym ......
Location	20q13.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

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Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant
Q9ULU4	404	T	Phosphothreonine	-	No	None detected
Q9ULU4	406	S	Phosphoserine	-	No	None detected
Q9ULU4	413	K	N6-acetyllysine	-	No	None detected
Q9ULU4	417	S	Phosphoserine	-	No	None detected
Q9ULU4	425	S	Phosphoserine	-	Yes	p.S425F (cancer: SKCM)
Q9ULU4	432	S	Phosphoserine	-	No	None detected
Q9ULU4	444	S	Phosphoserine	-	No	None detected
Q9ULU4	460	S	Phosphoserine	-	No	None detected
Q9ULU4	462	S	Phosphoserine	-	No	None detected
Q9ULU4	465	S	Phosphoserine	-	No	None detected
Q9ULU4	486	S	Phosphoserine	-	No	None detected
Q9ULU4	490	S	Phosphoserine	-	No	None detected
Q9ULU4	495	S	Phosphoserine	-	No	None detected
Q9ULU4	514	S	Phosphoserine	-	No	None detected
Q9ULU4	523	S	Phosphoserine	-	No	None detected
Q9ULU4	541	T	Phosphothreonine	-	No	None detected
Q9ULU4	547	S	Phosphoserine	-	No	None detected
Q9ULU4	563	T	Phosphothreonine	-	No	None detected
Q9ULU4	652	S	Phosphoserine	-	No	None detected
Q9ULU4	655	S	Phosphoserine	-	No	None detected
Q9ULU4	668	S	Phosphoserine	-	No	None detected
Q9ULU4	682	S	Phosphoserine	-	Yes	p.S682* (cancer: BLCA)
Q9ULU4	707	S	Phosphoserine	-	No	None detected
Q9ULU4	709	S	Phosphoserine	-	No	None detected
Q9ULU4	737	S	Phosphoserine	-	No	None detected
Q9ULU4	746	T	Phosphothreonine	-	No	None detected
Q9ULU4	754	S	Phosphoserine	-	No	None detected
Q9ULU4	756	S	Phosphoserine	-	No	None detected
Q9ULU4	1119	S	Phosphoserine	-	No	None detected
Q9ULU4	1141	S	Phosphoserine	-	No	None detected

Summary
Symbol	ZMYND8
Name	zinc finger MYND-type containing 8
Aliases	RACK7; PRKCBP1; protein kinase C binding protein 1; PRO2893; CTCL tumor antigen se14-3; cutaneous T-cell lym ......
Location	20q13.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

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Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	5.681	5.953	0.451	0.0433	NS
BRCA	Breast invasive carcinoma	112	1100	5.596	6.035	0.514	6.02e-12	NS
CESC	Cervical and endocervical cancers	3	306	4.42	5.285	NA	NA	NA
COAD	Colon adenocarcinoma	41	459	5.864	6.277	0.443	0.000458	NS
ESCA	Esophageal carcinoma	11	185	6.833	6.531	-0.308	0.15	NS
GBM	Glioblastoma multiforme	5	166	6.338	5.52	NA	NA	NA
HNSC	Head and Neck squamous cell carcinoma	44	522	5.162	5.096	-0.087	0.476	NS
KIRC	Kidney renal clear cell carcinoma	72	534	5.564	5.353	-0.181	0.0182	NS
KIRP	Kidney renal papillary cell carcinoma	32	291	5.392	5.519	0.037	0.77	NS
LAML	Acute Myeloid Leukemia	0	173	NA	7.219	NA	NA	NA
LGG	Brain Lower Grade Glioma	0	530	NA	5.859	NA	NA	NA
LIHC	Liver hepatocellular carcinoma	50	373	3.682	3.886	0.297	0.0051	NS
LUAD	Lung adenocarcinoma	59	517	5.546	5.796	0.406	6.29e-06	NS
LUSC	Lung squamous cell carcinoma	51	501	5.362	5.616	0.365	0.000361	NS
OV	Ovarian serous cystadenocarcinoma	0	307	NA	6.611	NA	NA	NA
PAAD	Pancreatic adenocarcinoma	4	179	5.527	5.647	NA	NA	NA
PCPG	Pheochromocytoma and Paraganglioma	3	184	6.397	6.059	NA	NA	NA
PRAD	Prostate adenocarcinoma	52	498	5.322	5.276	-0.001	0.99	NS
READ	Rectum adenocarcinoma	10	167	5.635	6.579	0.895	0.000174	Over
SARC	Sarcoma	2	263	4.425	4.936	NA	NA	NA
SKCM	Skin Cutaneous Melanoma	1	472	5.343	6.268	NA	NA	NA
STAD	Stomach adenocarcinoma	35	415	6.255	6.443	0.275	0.0713	NS
TGCT	Testicular Germ Cell Tumors	0	156	NA	6.426	NA	NA	NA
THCA	Thyroid carcinoma	59	509	5.104	5.354	0.253	7.95e-05	NS
THYM	Thymoma	2	120	5.485	4.901	NA	NA	NA
UCEC	Uterine Corpus Endometrial Carcinoma	35	546	5.382	6.29	0.813	8.08e-11	Over

> Cancer Cell Line Encyclopedia (CCLE)

[ TOP ]

Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	9.3
Autonomic ganglia	CHP212	9
Autonomic ganglia	IMR32	8.4
Autonomic ganglia	KELLY	9.8
Autonomic ganglia	KPNRTBM1	10.1
Autonomic ganglia	KPNSI9S	10
Autonomic ganglia	KPNYN	9.6
Autonomic ganglia	MHHNB11	8.1
Autonomic ganglia	NB1	9.5
Autonomic ganglia	NH6	8.8
Autonomic ganglia	SHSY5Y	8.8
Autonomic ganglia	SIMA	9.7
Autonomic ganglia	SKNAS	10.3
Autonomic ganglia	SKNBE2	10.5
Autonomic ganglia	SKNDZ	11
Autonomic ganglia	SKNFI	9
Autonomic ganglia	SKNSH	8.9
Biliary tract	HUCCT1	8.9
Biliary tract	HUH28	9.9
Biliary tract	SNU1079	10.2
Biliary tract	SNU1196	9.5
Biliary tract	SNU245	9.1
Biliary tract	SNU308	9.7
Biliary tract	SNU478	8.6
Bone	143B	9
Bone	A673	8.3
Bone	CADOES1	9
Bone	CAL78	8.6
Bone	G292CLONEA141B1	9.4
Bone	HOS	8.7
Bone	HS706T	8.3
Bone	HS737T	8.6
Bone	HS819T	8.3
Bone	HS821T	8
Bone	HS822T	8.7
Bone	HS863T	8.4
Bone	HS870T	8.2
Bone	HS888T	9.3
Bone	MG63	9.4
Bone	MHHES1	9.7
Bone	OUMS27	9.4
Bone	RDES	9.8
Bone	SJSA1	8.9
Bone	SKES1	9.8
Bone	SKNMC	8.6
Bone	SW1353	9.9
Bone	T173	8.2
Bone	TC71	9.9
Bone	U2OS	9.2
Breast	AU565	9.7
Breast	BT20	11.1
Breast	BT474	10.3
Breast	BT483	10.2
Breast	BT549	9.1
Breast	CAL120	10.7
Breast	CAL148	9.2
Breast	CAL51	10.1
Breast	CAL851	9
Breast	CAMA1	9.7
Breast	DU4475	10.1
Breast	EFM192A	9.9
Breast	EFM19	9.8
Breast	EVSAT	8.3
Breast	HCC1143	10.1
Breast	HCC1187	9.9
Breast	HCC1395	9.4
Breast	HCC1419	11.2
Breast	HCC1428	8.2
Breast	HCC1500	8.9
Breast	HCC1569	10.9
Breast	HCC1599	7.4
Breast	HCC1806	9.5
Breast	HCC1937	10.1
Breast	HCC1954	9.6
Breast	HCC202	10.3
Breast	HCC2157	9
Breast	HCC2218	8.9
Breast	HCC38	8.2
Breast	HCC70	9.9
Breast	HDQP1	9.7
Breast	HMC18	11
Breast	HS274T	8.6
Breast	HS281T	8.1
Breast	HS343T	8.5
Breast	HS578T	7.6
Breast	HS606T	7.9
Breast	HS739T	8.2
Breast	HS742T	8.1
Breast	JIMT1	10.3
Breast	KPL1	10.5
Breast	MCF7	10.4
Breast	MDAMB134VI	10.7
Breast	MDAMB157	8.8
Breast	MDAMB175VII	10.9
Breast	MDAMB231	9.6
Breast	MDAMB361	11
Breast	MDAMB415	9.5
Breast	MDAMB436	8.8
Breast	MDAMB453	10.1
Breast	MDAMB468	9.4
Breast	SKBR3	9.6
Breast	T47D	9.2
Breast	UACC812	9.7
Breast	UACC893	8.9
Breast	YMB1	9.9
Breast	ZR751	10
Breast	ZR7530	9.9
Central nervous system	1321N1	10.1
Central nervous system	42MGBA	9
Central nervous system	8MGBA	9.1
Central nervous system	A172	9
Central nervous system	AM38	8.7
Central nervous system	BECKER	9.1
Central nervous system	CAS1	9.4
Central nervous system	CCFSTTG1	7.9
Central nervous system	D283MED	9.1
Central nervous system	D341MED	8.2
Central nervous system	DAOY	9.2
Central nervous system	DBTRG05MG	9.9
Central nervous system	DKMG	8.2
Central nervous system	GAMG	9
Central nervous system	GB1	9.2
Central nervous system	GI1	10.5
Central nervous system	GMS10	8.8
Central nervous system	GOS3	9.5
Central nervous system	H4	8.8
Central nervous system	HS683	9.1
Central nervous system	KALS1	9
Central nervous system	KG1C	11.3
Central nervous system	KNS42	8.7
Central nervous system	KNS60	9.3
Central nervous system	KNS81	8.7
Central nervous system	KS1	9.3
Central nervous system	LN18	9.6
Central nervous system	LN229	9.4
Central nervous system	M059K	8.2
Central nervous system	MOGGCCM	8.7
Central nervous system	MOGGUVW	9.5
Central nervous system	NMCG1	8.7
Central nervous system	ONS76	10.2
Central nervous system	SF126	9.3
Central nervous system	SF295	8.8
Central nervous system	SNB19	8.6
Central nervous system	SNU1105	8.6
Central nervous system	SNU201	8.8
Central nervous system	SNU466	9.6
Central nervous system	SNU489	9.6
Central nervous system	SNU626	8.9
Central nervous system	SNU738	9.8
Central nervous system	SW1088	9.8
Central nervous system	SW1783	8.7
Central nervous system	T98G	9.4
Central nervous system	TM31	8.2
Central nervous system	U118MG	8.6
Central nervous system	U138MG	9.5
Central nervous system	U251MG	8.6
Central nervous system	U87MG	10.6
Central nervous system	YH13	8.7
Central nervous system	YKG1	9.6
Endometrium	AN3CA	9.7
Endometrium	COLO684	9.5
Endometrium	EFE184	9.4
Endometrium	EN	9.2
Endometrium	ESS1	8.5
Endometrium	HEC108	10.4
Endometrium	HEC151	9
Endometrium	HEC1A	9.1
Endometrium	HEC1B	9.4
Endometrium	HEC251	10
Endometrium	HEC265	8.8
Endometrium	HEC50B	10.8
Endometrium	HEC59	8.7
Endometrium	HEC6	8.3
Endometrium	ISHIKAWAHERAKLIO02ER	8.5
Endometrium	JHUEM1	8.3
Endometrium	JHUEM2	9.6
Endometrium	JHUEM3	9.7
Endometrium	KLE	9
Endometrium	MFE280	8.8
Endometrium	MFE296	9.2
Endometrium	MFE319	7.5
Endometrium	RL952	8.5
Endometrium	SNGM	9.6
Endometrium	SNU1077	9.8
Endometrium	SNU685	9.6
Endometrium	TEN	10.5
Haematopoietic and lymphoid	697	10.4
Haematopoietic and lymphoid	A3KAW	9.1
Haematopoietic and lymphoid	A4FUK	9.9
Haematopoietic and lymphoid	ALLSIL	9.4
Haematopoietic and lymphoid	AML193	9
Haematopoietic and lymphoid	AMO1	9.1
Haematopoietic and lymphoid	BCP1	9.6
Haematopoietic and lymphoid	BDCM	9.8
Haematopoietic and lymphoid	BL41	9.1
Haematopoietic and lymphoid	BL70	9.7
Haematopoietic and lymphoid	BV173	9.8
Haematopoietic and lymphoid	CA46	9.8
Haematopoietic and lymphoid	CI1	9.5
Haematopoietic and lymphoid	CMK115	11.2
Haematopoietic and lymphoid	CMK86	11.5
Haematopoietic and lymphoid	CMK	11.2
Haematopoietic and lymphoid	CMLT1	9.8
Haematopoietic and lymphoid	COLO775	9.2
Haematopoietic and lymphoid	DAUDI	9.5
Haematopoietic and lymphoid	DB	9.5
Haematopoietic and lymphoid	DEL	9.1
Haematopoietic and lymphoid	DND41	8.8
Haematopoietic and lymphoid	DOHH2	9.6
Haematopoietic and lymphoid	EB1	9.6
Haematopoietic and lymphoid	EB2	9.7
Haematopoietic and lymphoid	EHEB	9.7
Haematopoietic and lymphoid	EJM	9.7
Haematopoietic and lymphoid	EM2	9.3
Haematopoietic and lymphoid	EOL1	8.7
Haematopoietic and lymphoid	F36P	10.4
Haematopoietic and lymphoid	GA10	9.6
Haematopoietic and lymphoid	GDM1	10.8
Haematopoietic and lymphoid	GRANTA519	9.8
Haematopoietic and lymphoid	HDLM2	7.7
Haematopoietic and lymphoid	HDMYZ	10.1
Haematopoietic and lymphoid	HEL9217	10.2
Haematopoietic and lymphoid	HEL	10.1
Haematopoietic and lymphoid	HH	8.3
Haematopoietic and lymphoid	HL60	9.9
Haematopoietic and lymphoid	HPBALL	8.4
Haematopoietic and lymphoid	HS604T	8.9
Haematopoietic and lymphoid	HS611T	9.6
Haematopoietic and lymphoid	HS616T	8.6
Haematopoietic and lymphoid	HS751T	7.9
Haematopoietic and lymphoid	HT	9
Haematopoietic and lymphoid	HTK	9
Haematopoietic and lymphoid	HUNS1	9.2
Haematopoietic and lymphoid	HUT102	9.3
Haematopoietic and lymphoid	HUT78	9.1
Haematopoietic and lymphoid	JEKO1	10.5
Haematopoietic and lymphoid	JK1	9.8
Haematopoietic and lymphoid	JM1	9.7
Haematopoietic and lymphoid	JURKAT	7.9
Haematopoietic and lymphoid	JURLMK1	11.2
Haematopoietic and lymphoid	JVM2	9.4
Haematopoietic and lymphoid	JVM3	9.6
Haematopoietic and lymphoid	K562	10.6
Haematopoietic and lymphoid	KARPAS299	9
Haematopoietic and lymphoid	KARPAS422	9.7
Haematopoietic and lymphoid	KARPAS620	8.9
Haematopoietic and lymphoid	KASUMI1	9.6
Haematopoietic and lymphoid	KASUMI2	10.7
Haematopoietic and lymphoid	KASUMI6	9.6
Haematopoietic and lymphoid	KCL22	9.5
Haematopoietic and lymphoid	KE37	8.3
Haematopoietic and lymphoid	KE97	9.3
Haematopoietic and lymphoid	KG1	10.4
Haematopoietic and lymphoid	KHM1B	8.1
Haematopoietic and lymphoid	KIJK	8.8
Haematopoietic and lymphoid	KMH2	7.8
Haematopoietic and lymphoid	KMM1	9.2
Haematopoietic and lymphoid	KMS11	8.7
Haematopoietic and lymphoid	KMS12BM	9.5
Haematopoietic and lymphoid	KMS18	9.4
Haematopoietic and lymphoid	KMS20	10.1
Haematopoietic and lymphoid	KMS21BM	8.8
Haematopoietic and lymphoid	KMS26	8.8
Haematopoietic and lymphoid	KMS27	9.4
Haematopoietic and lymphoid	KMS28BM	9.6
Haematopoietic and lymphoid	KMS34	9.5
Haematopoietic and lymphoid	KO52	10.3
Haematopoietic and lymphoid	KOPN8	9.9
Haematopoietic and lymphoid	KU812	10.2
Haematopoietic and lymphoid	KYO1	10.6
Haematopoietic and lymphoid	L1236	9
Haematopoietic and lymphoid	L363	10.2
Haematopoietic and lymphoid	L428	7.3
Haematopoietic and lymphoid	L540	8.4
Haematopoietic and lymphoid	LAMA84	10.2
Haematopoietic and lymphoid	LOUCY	10.4
Haematopoietic and lymphoid	LP1	8.2
Haematopoietic and lymphoid	M07E	11.3
Haematopoietic and lymphoid	MC116	9.3
Haematopoietic and lymphoid	ME1	10.6
Haematopoietic and lymphoid	MEC1	9.6
Haematopoietic and lymphoid	MEC2	10
Haematopoietic and lymphoid	MEG01	11.2
Haematopoietic and lymphoid	MHHCALL2	10.2
Haematopoietic and lymphoid	MHHCALL3	10.6
Haematopoietic and lymphoid	MHHCALL4	10.9
Haematopoietic and lymphoid	MINO	10.1
Haematopoietic and lymphoid	MJ	8.7
Haematopoietic and lymphoid	MM1S	9.6
Haematopoietic and lymphoid	MOLM13	9.2
Haematopoietic and lymphoid	MOLM16	11.2
Haematopoietic and lymphoid	MOLM6	8.9
Haematopoietic and lymphoid	MOLP2	9.1
Haematopoietic and lymphoid	MOLP8	9.7
Haematopoietic and lymphoid	MOLT13	8.5
Haematopoietic and lymphoid	MOLT16	7.4
Haematopoietic and lymphoid	MOLT4	8.1
Haematopoietic and lymphoid	MONOMAC1	9.3
Haematopoietic and lymphoid	MONOMAC6	9
Haematopoietic and lymphoid	MOTN1	8.8
Haematopoietic and lymphoid	MUTZ5	10.4
Haematopoietic and lymphoid	MV411	9.7
Haematopoietic and lymphoid	NALM19	9.8
Haematopoietic and lymphoid	NALM1	10.4
Haematopoietic and lymphoid	NALM6	9.2
Haematopoietic and lymphoid	NAMALWA	10.1
Haematopoietic and lymphoid	NB4	10
Haematopoietic and lymphoid	NCIH929	10
Haematopoietic and lymphoid	NCO2	10.8
Haematopoietic and lymphoid	NOMO1	9.1
Haematopoietic and lymphoid	NUDHL1	9.8
Haematopoietic and lymphoid	NUDUL1	10.2
Haematopoietic and lymphoid	OCIAML2	8.9
Haematopoietic and lymphoid	OCIAML3	9.3
Haematopoietic and lymphoid	OCIAML5	8.6
Haematopoietic and lymphoid	OCILY10	9.7
Haematopoietic and lymphoid	OCILY19	10.1
Haematopoietic and lymphoid	OCILY3	9.1
Haematopoietic and lymphoid	OCIM1	10.6
Haematopoietic and lymphoid	OPM2	9.4
Haematopoietic and lymphoid	P12ICHIKAWA	9.2
Haematopoietic and lymphoid	P31FUJ	8.7
Haematopoietic and lymphoid	P3HR1	10
Haematopoietic and lymphoid	PCM6	8.4
Haematopoietic and lymphoid	PEER	8.9
Haematopoietic and lymphoid	PF382	8.3
Haematopoietic and lymphoid	PFEIFFER	9.3
Haematopoietic and lymphoid	PL21	8.9
Haematopoietic and lymphoid	RAJI	9.4
Haematopoietic and lymphoid	RCHACV	9.9
Haematopoietic and lymphoid	REC1	8.9
Haematopoietic and lymphoid	REH	10.9
Haematopoietic and lymphoid	RI1	9.4
Haematopoietic and lymphoid	RL	9.4
Haematopoietic and lymphoid	RPMI8226	9.7
Haematopoietic and lymphoid	RPMI8402	9.5
Haematopoietic and lymphoid	RS411	10.9
Haematopoietic and lymphoid	SEM	10.7
Haematopoietic and lymphoid	SET2	11.4
Haematopoietic and lymphoid	SIGM5	9.6
Haematopoietic and lymphoid	SKM1	8.9
Haematopoietic and lymphoid	SKMM2	9.4
Haematopoietic and lymphoid	SR786	7.8
Haematopoietic and lymphoid	ST486	9.3
Haematopoietic and lymphoid	SUDHL10	9.6
Haematopoietic and lymphoid	SUDHL1	8.4
Haematopoietic and lymphoid	SUDHL4	9.7
Haematopoietic and lymphoid	SUDHL5	9.4
Haematopoietic and lymphoid	SUDHL6	9.5
Haematopoietic and lymphoid	SUDHL8	10.2
Haematopoietic and lymphoid	SUPB15	10.6
Haematopoietic and lymphoid	SUPHD1	8.6
Haematopoietic and lymphoid	SUPM2	7.9
Haematopoietic and lymphoid	SUPT11	9.5
Haematopoietic and lymphoid	SUPT1	9.5
Haematopoietic and lymphoid	TALL1	10.1
Haematopoietic and lymphoid	TF1	10.5
Haematopoietic and lymphoid	THP1	8.4
Haematopoietic and lymphoid	TO175T	8.8
Haematopoietic and lymphoid	TOLEDO	9.1
Haematopoietic and lymphoid	U266B1	9.9
Haematopoietic and lymphoid	U937	9.5
Haematopoietic and lymphoid	UT7	11.9
Haematopoietic and lymphoid	WSUDLCL2	9.8
Kidney	769P	9.6
Kidney	786O	9.5
Kidney	A498	10
Kidney	A704	9.2
Kidney	ACHN	9.5
Kidney	BFTC909	9.1
Kidney	CAKI1	9.5
Kidney	CAKI2	10.1
Kidney	CAL54	10.3
Kidney	KMRC1	8.7
Kidney	KMRC20	8.8
Kidney	KMRC2	9.2
Kidney	KMRC3	8.8
Kidney	OSRC2	10.3
Kidney	RCC10RGB	9.6
Kidney	SNU1272	8.7
Kidney	SNU349	9
Kidney	TUHR10TKB	8.3
Kidney	TUHR14TKB	9.7
Kidney	TUHR4TKB	9.7
Kidney	VMRCRCW	10.7
Kidney	VMRCRCZ	9.7
Large intestine	C2BBE1	10.6
Large intestine	CCK81	8.6
Large intestine	CL11	9.7
Large intestine	CL14	10.3
Large intestine	CL34	8.9
Large intestine	CL40	9.8
Large intestine	COLO205	10.7
Large intestine	COLO320	9.5
Large intestine	COLO678	9.9
Large intestine	CW2	7.4
Large intestine	DLD1	8.8
Large intestine	GP2D	8.7
Large intestine	HCC56	10.2
Large intestine	HCT116	8.5
Large intestine	HCT15	8.6
Large intestine	HS675T	8.5
Large intestine	HS698T	8.4
Large intestine	HT115	8.5
Large intestine	HT29	10.3
Large intestine	HT55	9.5
Large intestine	KM12	9.1
Large intestine	LOVO	8.4
Large intestine	LS1034	10.3
Large intestine	LS123	9.6
Large intestine	LS180	8.9
Large intestine	LS411N	9
Large intestine	LS513	8.5
Large intestine	MDST8	8.7
Large intestine	NCIH508	10
Large intestine	NCIH716	10.8
Large intestine	NCIH747	10.4
Large intestine	OUMS23	10.3
Large intestine	RCM1	11.4
Large intestine	RKO	8.5
Large intestine	SKCO1	9.2
Large intestine	SNU1040	8.3
Large intestine	SNU1197	9.9
Large intestine	SNU175	7.5
Large intestine	SNU283	9.7
Large intestine	SNU407	8.9
Large intestine	SNU503	9.5
Large intestine	SNU61	9.1
Large intestine	SNU81	9.5
Large intestine	SNUC1	10.5
Large intestine	SNUC2A	8.1
Large intestine	SNUC4	8.5
Large intestine	SNUC5	9.3
Large intestine	SW1116	9.8
Large intestine	SW1417	10.2
Large intestine	SW1463	9.9
Large intestine	SW403	9.8
Large intestine	SW480	9.8
Large intestine	SW48	8.4
Large intestine	SW620	10.5
Large intestine	SW837	9.1
Large intestine	SW948	9.8
Large intestine	T84	9.3
Liver	ALEXANDERCELLS	8.8
Liver	C3A	10.5
Liver	HEP3B217	10
Liver	HEPG2	10.5
Liver	HLE	9.3
Liver	HLF	10.2
Liver	HUH1	9.1
Liver	HUH6	10.3
Liver	HUH7	9.4
Liver	JHH1	10.5
Liver	JHH2	9.5
Liver	JHH4	10.5
Liver	JHH5	9.5
Liver	JHH6	9.2
Liver	JHH7	10
Liver	LI7	8.7
Liver	PLCPRF5	9.7
Liver	SKHEP1	9.5
Liver	SNU182	9.3
Liver	SNU387	9.5
Liver	SNU398	9.2
Liver	SNU423	10.3
Liver	SNU449	9.6
Liver	SNU475	9.3
Liver	SNU761	9.5
Liver	SNU878	9.4
Liver	SNU886	9.7
Lung	A549	8.3
Lung	ABC1	8.7
Lung	BEN	10.7
Lung	CAL12T	8
Lung	CALU1	9.6
Lung	CALU3	8.8
Lung	CALU6	10.7
Lung	CHAGOK1	8.3
Lung	COLO668	10.5
Lung	COLO699	8.7
Lung	CORL105	8.4
Lung	CORL23	10.8
Lung	CORL24	10.2
Lung	CORL279	9.7
Lung	CORL311	10.9
Lung	CORL47	9.2
Lung	CORL51	9.8
Lung	CORL88	10.3
Lung	CORL95	9.1
Lung	CPCN	10.3
Lung	DMS114	10.5
Lung	DMS153	10.3
Lung	DMS273	8.6
Lung	DMS454	8.7
Lung	DMS53	9.5
Lung	DMS79	8.5
Lung	DV90	9.5
Lung	EBC1	9.8
Lung	EPLC272H	9.7
Lung	HARA	7.7
Lung	HCC1171	9.6
Lung	HCC1195	8.9
Lung	HCC15	8.6
Lung	HCC2279	9.5
Lung	HCC2935	10
Lung	HCC33	9.4
Lung	HCC366	8
Lung	HCC4006	8.3
Lung	HCC44	8.1
Lung	HCC78	8.9
Lung	HCC827	9.5
Lung	HCC95	8.9
Lung	HLC1	10.3
Lung	HLFA	7.7
Lung	HS229T	8.6
Lung	HS618T	8.2
Lung	IALM	9
Lung	KNS62	9.3
Lung	LC1F	10.1
Lung	LC1SQSF	9
Lung	LCLC103H	8.7
Lung	LCLC97TM1	9.2
Lung	LK2	9
Lung	LOUNH91	8.7
Lung	LU65	9.4
Lung	LU99	10.4
Lung	LUDLU1	9.1
Lung	LXF289	8.3
Lung	MORCPR	10.8
Lung	NCIH1048	9.2
Lung	NCIH1092	9.3
Lung	NCIH1105	10
Lung	NCIH1155	8.7
Lung	NCIH1184	8.9
Lung	NCIH1299	10.1
Lung	NCIH1339	8.1
Lung	NCIH1341	10.2
Lung	NCIH1355	7.5
Lung	NCIH1373	8.9
Lung	NCIH1385	9.5
Lung	NCIH1395	8.6
Lung	NCIH1435	9
Lung	NCIH1436	8.7
Lung	NCIH1437	9.4
Lung	NCIH146	9.3
Lung	NCIH1563	9
Lung	NCIH1568	8.4
Lung	NCIH1573	10.1
Lung	NCIH1581	9.5
Lung	NCIH1618	9.6
Lung	NCIH1623	8.1
Lung	NCIH1648	10.5
Lung	NCIH1650	8.6
Lung	NCIH1651	8.9
Lung	NCIH1666	10.2
Lung	NCIH1693	9.4
Lung	NCIH1694	9.7
Lung	NCIH1703	8.8
Lung	NCIH1734	8.7
Lung	NCIH1755	10.4
Lung	NCIH1781	9.9
Lung	NCIH1792	9.4
Lung	NCIH1793	9.5
Lung	NCIH1836	10.8
Lung	NCIH1838	8.8
Lung	NCIH1869	8.8
Lung	NCIH1876	9.4
Lung	NCIH1915	9.1
Lung	NCIH1930	9.2
Lung	NCIH1944	7.2
Lung	NCIH1963	9.8
Lung	NCIH196	8.5
Lung	NCIH1975	9.7
Lung	NCIH2009	9.4
Lung	NCIH2023	8.3
Lung	NCIH2029	10.7
Lung	NCIH2030	9.5
Lung	NCIH2066	9.3
Lung	NCIH2081	9.4
Lung	NCIH2085	10
Lung	NCIH2087	9.9
Lung	NCIH209	9.4
Lung	NCIH2106	9
Lung	NCIH2110	9
Lung	NCIH211	9.3
Lung	NCIH2122	9.2
Lung	NCIH2126	9.1
Lung	NCIH2141	9.9
Lung	NCIH2170	9.8
Lung	NCIH2171	9.8
Lung	NCIH2172	8.9
Lung	NCIH2196	9.7
Lung	NCIH2227	9.7
Lung	NCIH2228	8.4
Lung	NCIH226	10.1
Lung	NCIH2286	8.8
Lung	NCIH2291	10
Lung	NCIH2342	9.2
Lung	NCIH2347	8.8
Lung	NCIH23	9.4
Lung	NCIH2405	9.5
Lung	NCIH2444	9.7
Lung	NCIH292	8.3
Lung	NCIH322	8.9
Lung	NCIH3255	10.6
Lung	NCIH358	9.7
Lung	NCIH441	10.2
Lung	NCIH446	9.8
Lung	NCIH460	8.8
Lung	NCIH510	10.2
Lung	NCIH520	9.6
Lung	NCIH522	9.4
Lung	NCIH524	9.6
Lung	NCIH526	9.7
Lung	NCIH596	9.7
Lung	NCIH647	8.9
Lung	NCIH650	9.4
Lung	NCIH661	8.6
Lung	NCIH69	9.1
Lung	NCIH727	10
Lung	NCIH810	9
Lung	NCIH82	9.6
Lung	NCIH838	8.8
Lung	NCIH841	8.9
Lung	NCIH854	11.4
Lung	NCIH889	9.2
Lung	PC14	9.9
Lung	RERFLCAD1	10.2
Lung	RERFLCAD2	9.3
Lung	RERFLCAI	8.3
Lung	RERFLCKJ	8.9
Lung	RERFLCMS	8.5
Lung	RERFLCSQ1	9.5
Lung	SBC5	10.7
Lung	SCLC21H	10.3
Lung	SHP77	9.5
Lung	SKLU1	9.2
Lung	SKMES1	8.4
Lung	SQ1	9.1
Lung	SW1271	10.8
Lung	SW1573	9.1
Lung	SW900	9.7
Lung	VMRCLCD	10.2
Lung	VMRCLCP	8.9
Oesophagus	COLO680N	9.3
Oesophagus	ECGI10	8.6
Oesophagus	KYSE140	8.8
Oesophagus	KYSE150	9.1
Oesophagus	KYSE180	8.5
Oesophagus	KYSE270	8.3
Oesophagus	KYSE30	10.8
Oesophagus	KYSE410	10
Oesophagus	KYSE450	8
Oesophagus	KYSE510	9.2
Oesophagus	KYSE520	9.7
Oesophagus	KYSE70	8.3
Oesophagus	OE19	9.2
Oesophagus	OE33	9.2
Oesophagus	TE10	10.1
Oesophagus	TE11	9.7
Oesophagus	TE14	8
Oesophagus	TE15	9.9
Oesophagus	TE1	9.3
Oesophagus	TE4	9.3
Oesophagus	TE5	9.4
Oesophagus	TE6	8.7
Oesophagus	TE8	10.3
Oesophagus	TE9	9.2
Oesophagus	TT	10
Ovary	59M	8.8
Ovary	A2780	10.7
Ovary	CAOV3	8.5
Ovary	CAOV4	9.8
Ovary	COLO704	9.3
Ovary	COV318	9.4
Ovary	COV362	8.2
Ovary	COV434	11
Ovary	COV504	10.4
Ovary	COV644	8.6
Ovary	EFO21	9.9
Ovary	EFO27	10.4
Ovary	ES2	10.1
Ovary	FUOV1	9.1
Ovary	HEYA8	10.3
Ovary	HS571T	8.8
Ovary	IGROV1	8.6
Ovary	JHOC5	7.4
Ovary	JHOM1	9.2
Ovary	JHOM2B	10.7
Ovary	JHOS2	9.1
Ovary	JHOS4	9.1
Ovary	KURAMOCHI	11.4
Ovary	MCAS	8.9
Ovary	NIHOVCAR3	8.5
Ovary	OAW28	9.1
Ovary	OAW42	9.1
Ovary	OC314	10.1
Ovary	OC316	9.7
Ovary	ONCODG1	8.6
Ovary	OV56	10.2
Ovary	OV7	8.8
Ovary	OV90	9.9
Ovary	OVCAR4	8.7
Ovary	OVCAR8	8.9
Ovary	OVISE	9.6
Ovary	OVK18	10.4
Ovary	OVKATE	7.9
Ovary	OVMANA	11.1
Ovary	OVSAHO	10.5
Ovary	OVTOKO	9.5
Ovary	RMGI	9.2
Ovary	RMUGS	9.2
Ovary	SKOV3	8.5
Ovary	SNU119	8.5
Ovary	SNU840	9.3
Ovary	SNU8	9.8
Ovary	TOV112D	9.7
Ovary	TOV21G	8.9
Ovary	TYKNU	10.1
Pancreas	ASPC1	10.4
Pancreas	BXPC3	9.3
Pancreas	CAPAN1	9.7
Pancreas	CAPAN2	9.5
Pancreas	CFPAC1	9.6
Pancreas	DANG	9.8
Pancreas	HPAC	9.3
Pancreas	HPAFII	10.6
Pancreas	HS766T	10.7
Pancreas	HUPT3	8.6
Pancreas	HUPT4	10.5
Pancreas	KCIMOH1	8.3
Pancreas	KLM1	9.1
Pancreas	KP2	9.8
Pancreas	KP3	10.7
Pancreas	KP4	10.6
Pancreas	L33	9.5
Pancreas	MIAPACA2	10.4
Pancreas	PANC0203	9.6
Pancreas	PANC0213	10.3
Pancreas	PANC0327	8.7
Pancreas	PANC0403	9.5
Pancreas	PANC0504	9.6
Pancreas	PANC0813	9.4
Pancreas	PANC1005	9.8
Pancreas	PANC1	8.8
Pancreas	PATU8902	9.4
Pancreas	PATU8988S	9.7
Pancreas	PATU8988T	9.6
Pancreas	PK1	10
Pancreas	PK45H	9.8
Pancreas	PK59	9.2
Pancreas	PL45	9.4
Pancreas	PSN1	10.1
Pancreas	QGP1	10.1
Pancreas	SNU213	9.7
Pancreas	SNU324	8.7
Pancreas	SNU410	9.9
Pancreas	SU8686	10
Pancreas	SUIT2	8.8
Pancreas	SW1990	9.5
Pancreas	T3M4	9.6
Pancreas	TCCPAN2	10.9
Pancreas	YAPC	9.2
Pleura	ACCMESO1	9.2
Pleura	DM3	8.2
Pleura	ISTMES1	9.5
Pleura	ISTMES2	9.2
Pleura	JL1	9.9
Pleura	MPP89	9.1
Pleura	MSTO211H	9.8
Pleura	NCIH2052	10.5
Pleura	NCIH2452	11
Pleura	NCIH28	9.2
Prostate	22RV1	8.3
Prostate	DU145	8.4
Prostate	LNCAPCLONEFGC	9.7
Prostate	MDAPCA2B	10
Prostate	NCIH660	9.4
Prostate	PC3	8
Prostate	VCAP	11.1
Salivary gland	A253	9.9
Salivary gland	YD15	9.4
Skin	A101D	10.2
Skin	A2058	9.4
Skin	A375	10.9
Skin	C32	9.7
Skin	CHL1	9.1
Skin	CJM	9.6
Skin	COLO679	9.8
Skin	COLO741	10
Skin	COLO783	10.8
Skin	COLO792	9.1
Skin	COLO800	9.9
Skin	COLO818	9.2
Skin	COLO829	10.3
Skin	COLO849	10.7
Skin	G361	9.3
Skin	GRM	10.1
Skin	HMCB	8.9
Skin	HS294T	10.6
Skin	HS600T	8.5
Skin	HS688AT	8.4
Skin	HS695T	10.4
Skin	HS839T	8.4
Skin	HS852T	10.1
Skin	HS895T	8.1
Skin	HS934T	7.9
Skin	HS936T	10.2
Skin	HS939T	10.2
Skin	HS940T	8.5
Skin	HS944T	9.5
Skin	HT144	10.5
Skin	IGR1	9.7
Skin	IGR37	9.9
Skin	IGR39	9.6
Skin	IPC298	9.9
Skin	K029AX	10
Skin	LOXIMVI	9.7
Skin	MALME3M	10.7
Skin	MDAMB435S	9.8
Skin	MELHO	10.1
Skin	MELJUSO	9.8
Skin	MEWO	10.1
Skin	RPMI7951	9.9
Skin	RVH421	10.5
Skin	SH4	10
Skin	SKMEL1	10
Skin	SKMEL24	10.2
Skin	SKMEL28	10.1
Skin	SKMEL2	10.3
Skin	SKMEL30	9.5
Skin	SKMEL31	10.5
Skin	SKMEL3	11.1
Skin	SKMEL5	9.4
Skin	UACC257	9.9
Skin	UACC62	10.9
Skin	WM115	11.1
Skin	WM1799	9.7
Skin	WM2664	10.7
Skin	WM793	9
Skin	WM88	10.1
Skin	WM983B	10.7
Small intestine	HUTU80	10.1
Soft tissue	A204	10.6
Soft tissue	G401	10.5
Soft tissue	G402	10.2
Soft tissue	GCT	10.2
Soft tissue	HS729	8.8
Soft tissue	HT1080	9.9
Soft tissue	KYM1	10.9
Soft tissue	MESSA	10.7
Soft tissue	RD	9.4
Soft tissue	RH30	8.1
Soft tissue	RH41	9.4
Soft tissue	RKN	10.8
Soft tissue	S117	10
Soft tissue	SJRH30	10.4
Soft tissue	SKLMS1	10.6
Soft tissue	SKUT1	9.3
Soft tissue	TE125T	8
Soft tissue	TE159T	8.4
Soft tissue	TE441T	9.5
Soft tissue	TE617T	9.4
Stomach	2313287	8.7
Stomach	AGS	9
Stomach	AZ521	9.6
Stomach	ECC10	9.5
Stomach	ECC12	10.3
Stomach	FU97	11
Stomach	GCIY	8.5
Stomach	GSS	7.6
Stomach	GSU	9.6
Stomach	HGC27	9.1
Stomach	HS746T	9.3
Stomach	HUG1N	10
Stomach	IM95	9.1
Stomach	KATOIII	8.6
Stomach	KE39	9.7
Stomach	LMSU	8.3
Stomach	MKN1	9.1
Stomach	MKN45	9.9
Stomach	MKN74	8.2
Stomach	MKN7	9.6
Stomach	NCCSTCK140	9.9
Stomach	NCIN87	10.2
Stomach	NUGC2	9.2
Stomach	NUGC3	10.6
Stomach	NUGC4	10.5
Stomach	OCUM1	9.7
Stomach	RERFGC1B	9.4
Stomach	SH10TC	9.9
Stomach	SNU16	9.4
Stomach	SNU1	11
Stomach	SNU216	10.5
Stomach	SNU520	9.8
Stomach	SNU5	9.3
Stomach	SNU601	10.4
Stomach	SNU620	9.5
Stomach	SNU668	9.3
Stomach	SNU719	11.2
Stomach	TGBC11TKB	8.5
Thyroid	8305C	9.7
Thyroid	8505C	10
Thyroid	BCPAP	10.1
Thyroid	BHT101	9.7
Thyroid	CAL62	10.1
Thyroid	CGTHW1	9.2
Thyroid	FTC133	9.3
Thyroid	FTC238	9.2
Thyroid	ML1	10.3
Thyroid	SW579	9.5
Thyroid	TT2609C02	8.9
Thyroid	TT	10.2
Upper aerodigestive tract	BHY	10.2
Upper aerodigestive tract	BICR16	8.3
Upper aerodigestive tract	BICR18	10.4
Upper aerodigestive tract	BICR22	9.9
Upper aerodigestive tract	BICR31	9.9
Upper aerodigestive tract	BICR56	9.9
Upper aerodigestive tract	BICR6	10
Upper aerodigestive tract	CAL27	10
Upper aerodigestive tract	CAL33	9.6
Upper aerodigestive tract	DETROIT562	8.9
Upper aerodigestive tract	FADU	9.9
Upper aerodigestive tract	HS840T	8.7
Upper aerodigestive tract	HSC2	9.3
Upper aerodigestive tract	HSC3	8.8
Upper aerodigestive tract	HSC4	10.1
Upper aerodigestive tract	PECAPJ15	9.5
Upper aerodigestive tract	PECAPJ34CLONEC12	8.8
Upper aerodigestive tract	PECAPJ41CLONED2	8.6
Upper aerodigestive tract	PECAPJ49	10
Upper aerodigestive tract	SCC15	9.2
Upper aerodigestive tract	SCC25	8.5
Upper aerodigestive tract	SCC4	10.5
Upper aerodigestive tract	SCC9	9.8
Upper aerodigestive tract	SNU1076	9.9
Upper aerodigestive tract	SNU1214	8.5
Upper aerodigestive tract	SNU46	9.9
Upper aerodigestive tract	SNU899	10.6
Upper aerodigestive tract	YD10B	9.7
Upper aerodigestive tract	YD38	9.7
Upper aerodigestive tract	YD8	9.7
Urinary tract	5637	8.6
Urinary tract	639V	8.4
Urinary tract	647V	9.1
Urinary tract	BC3C	8.9
Urinary tract	BFTC905	9.6
Urinary tract	CAL29	8.5
Urinary tract	HS172T	7.5
Urinary tract	HT1197	8.7
Urinary tract	HT1376	9.7
Urinary tract	J82	9.5
Urinary tract	JMSU1	9.7
Urinary tract	KMBC2	9
Urinary tract	KU1919	10.9
Urinary tract	RT11284	10.1
Urinary tract	RT112	10.5
Urinary tract	RT4	9.6
Urinary tract	SCABER	8.4
Urinary tract	SW1710	8.9
Urinary tract	SW780	10.5
Urinary tract	T24	9.6
Urinary tract	TCCSUP	9.3
Urinary tract	UMUC1	10.3
Urinary tract	UMUC3	9
Urinary tract	VMCUB1	9.4

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	12.7
Adrenal gland	31.6
Appendix	14.4
Bone marrow	16.6
Breast	18.1
Cerebral cortex	29.5
Cervix, uterine	15.5
Colon	14.3
Duodenum	11.4
Endometrium	16.2
Epididymis	39.8
Esophagus	13.1
Fallopian tube	25.5
Gallbladder	19.4
Heart muscle	5.9
Kidney	11.8
Liver	4.2
Lung	16.8
Lymph node	15
Ovary	16.7
Pancreas	2.5
Parathyroid gland	23.7
Placenta	16.8
Prostate	14.5
Rectum	16.2
Salivary gland	5.6
Seminal vesicle	20.4
Skeletal muscle	3.6
Skin	19.9
Small intestine	15
Smooth muscle	12.6
Spleen	21.2
Stomach	18.7
Testis	24.5
Thyroid gland	18.4
Tonsil	12.1
Urinary bladder	19.2

> Text Mining based Expression

[ TOP ]

PMID	Expression	Cancer	Evidence
28432260	underexpression	Invasive Ductal and Lobular Breast Cancer	In concert with this, we observed a significant down-regulation of ZMYND8 in invasive ductal and lobular breast cancer tissues compared with normal tissue.
25117453	Overexpression	Prostate Carcinoma	Using transcriptome analyses, we found upregulation of ZMYND8 expression in both zebrafish prostate cancer xenografts and prostate cancer samples from patients.

Summary
Symbol	ZMYND8
Name	zinc finger MYND-type containing 8
Aliases	RACK7; PRKCBP1; protein kinase C binding protein 1; PRO2893; CTCL tumor antigen se14-3; cutaneous T-cell lym ......
Location	20q13.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.276	1.74e-08	2.7	36.4	60.9	Gain
BRCA	Breast invasive carcinoma	1075	0.359	4.66e-34	5.3	48.7	46	Gain
CESC	Cervical and endocervical cancers	292	0.205	0.000435	5.8	54.5	39.7	Gain
COAD	Colon adenocarcinoma	449	0.594	2.99e-44	0	27.6	72.4	Gain
ESCA	Esophageal carcinoma	183	0.271	0.000202	2.2	32.2	65.6	Gain
GBM	Glioblastoma multiforme	147	0.076	0.36	2	61.2	36.7	Gain
HNSC	Head and Neck squamous cell carcinoma	514	0.225	2.67e-07	6.4	55.8	37.7	Gain
KIRC	Kidney renal clear cell carcinoma	525	0.427	1.21e-24	0	77.1	22.9	Neutral
KIRP	Kidney renal papillary cell carcinoma	288	0.377	3.73e-11	0.3	64.6	35.1	Gain
LAML	Acute Myeloid Leukemia	166	0.007	0.924	1.8	98.2	0	Neutral
LGG	Brain Lower Grade Glioma	513	0.102	0.0209	1.4	90.1	8.6	Neutral
LIHC	Liver hepatocellular carcinoma	364	0.07	0.181	3.6	64	32.4	Neutral
LUAD	Lung adenocarcinoma	512	0.303	2.52e-12	14.1	43.8	42.2	Gain
LUSC	Lung squamous cell carcinoma	498	0.319	3.2e-13	9.4	38	52.6	Gain
OV	Ovarian serous cystadenocarcinoma	300	0.324	8.89e-09	3	28.7	68.3	Gain
PAAD	Pancreatic adenocarcinoma	177	0.481	1.25e-11	2.3	72.3	25.4	Neutral
PCPG	Pheochromocytoma and Paraganglioma	162	0.27	0.000517	2.5	90.7	6.8	Neutral
PRAD	Prostate adenocarcinoma	491	0.156	0.000513	2.4	90	7.5	Neutral
READ	Rectum adenocarcinoma	164	0.455	9.52e-10	0	11	89	Gain
SARC	Sarcoma	255	0.224	0.000316	5.9	55.3	38.8	Gain
SKCM	Skin Cutaneous Melanoma	367	0.371	1.93e-13	1.9	47.7	50.4	Gain
STAD	Stomach adenocarcinoma	413	0.548	9.73e-34	0.7	32.4	66.8	Gain
TGCT	Testicular Germ Cell Tumors	150	0.229	0.00488	8	63.3	28.7	Neutral
THCA	Thyroid carcinoma	497	-0.024	0.589	0	97.6	2.4	Neutral
THYM	Thymoma	119	-0.008	0.933	0.8	90.8	8.4	Neutral
UCEC	Uterine Corpus Endometrial Carcinoma	537	0.224	1.52e-07	1.9	70	28.1	Neutral

Summary
Symbol	ZMYND8
Name	zinc finger MYND-type containing 8
Aliases	RACK7; PRKCBP1; protein kinase C binding protein 1; PRO2893; CTCL tumor antigen se14-3; cutaneous T-cell lym ......
Location	20q13.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

[ TOP ]

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.518	0	17	408	-0.077	1.92e-05	NS/NA
BRCA	Breast invasive carcinoma	-0.398	0	83	785	-0.041	5.16e-17	NS/NA
CESC	Cervical and endocervical cancers	-0.385	3.11e-12	3	306	NA	NA	NS/NA
COAD	Colon adenocarcinoma	-0.256	4.4e-06	19	297	-0.001	0.738	NS/NA
ESCA	Esophageal carcinoma	-0.364	2.18e-07	9	185	NA	NA	NS/NA
GBM	Glioblastoma multiforme	-0.375	0.00222	1	64	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.401	0	20	522	0.026	5.71e-07	NS/NA
KIRC	Kidney renal clear cell carcinoma	-0.134	0.0132	24	319	-0.001	0.143	NS/NA
KIRP	Kidney renal papillary cell carcinoma	-0.214	0.000198	23	275	-0.018	0.000244	NS/NA
LAML	Acute Myeloid Leukemia	-0.457	5.59e-10	0	170	NA	NA	NS/NA
LGG	Brain Lower Grade Glioma	-0.209	1.25e-06	0	530	NA	NA	NS/NA
LIHC	Liver hepatocellular carcinoma	-0.32	3.4e-11	41	373	-0.096	0.729	NS/NA
LUAD	Lung adenocarcinoma	-0.331	1.67e-13	21	456	-0.084	1.86e-07	NS/NA
LUSC	Lung squamous cell carcinoma	-0.365	3.04e-13	8	370	NA	NA	NS/NA
OV	Ovarian serous cystadenocarcinoma	0	1	0	9	NA	NA	NS/NA
PAAD	Pancreatic adenocarcinoma	-0.371	2.91e-07	4	179	NA	NA	NS/NA
PCPG	Pheochromocytoma and Paraganglioma	-0.306	2.26e-05	3	184	NA	NA	NS/NA
PRAD	Prostate adenocarcinoma	-0.182	2.38e-05	35	498	-0.02	0.000705	NS/NA
READ	Rectum adenocarcinoma	-0.269	0.00673	2	99	NA	NA	NS/NA
SARC	Sarcoma	-0.507	0	0	263	NA	NA	NS/NA
SKCM	Skin Cutaneous Melanoma	-0.323	8.32e-13	1	471	NA	NA	NS/NA
STAD	Stomach adenocarcinoma	-0.286	2.32e-08	0	372	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.166	0.039	0	156	NA	NA	NS/NA
THCA	Thyroid carcinoma	-0.228	5.63e-08	50	509	-0.018	0.253	NS/NA
THYM	Thymoma	-0.371	2.97e-05	2	120	NA	NA	NS/NA
UCEC	Uterine Corpus Endometrial Carcinoma	-0.294	1.18e-10	34	431	-0.178	7e-20	NS/NA

Summary
Symbol	ZMYND8
Name	zinc finger MYND-type containing 8
Aliases	RACK7; PRKCBP1; protein kinase C binding protein 1; PRO2893; CTCL tumor antigen se14-3; cutaneous T-cell lym ......
Location	20q13.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Level	Level Name
Adrenal gland	2	Medium
Appendix	2	Medium
Bone marrow	2	Medium
Breast	2	Medium
Bronchus	2	Medium
Caudate	2	Medium
Cerebellum	3	High
Cerebral cortex	3	High
Cervix, uterine	1	Low
Colon	2	Medium
Duodenum	2	Medium
Endometrium	1	Low
Epididymis	2	Medium
Esophagus	1	Low
Fallopian tube	2	Medium
Gallbladder	3	High
Heart muscle	1	Low
Hippocampus	2	Medium
Kidney	1	Low
Liver	1	Low
Lung	2	Medium
Lymph node	1	Low
Nasopharynx	2	Medium
Oral mucosa	2	Medium
Ovary	0	Not detected
Pancreas	2	Medium
Parathyroid gland	2	Medium
Placenta	2	Medium
Prostate	1	Low
Rectum	2	Medium
Salivary gland	1	Low
Seminal vesicle	1	Low
Skeletal muscle	2	Medium
Skin	2	Medium
Small intestine	2	Medium
Smooth muscle	1	Low
Soft tissue	1	Low
Spleen	1	Low
Stomach	2	Medium
Testis	2	Medium
Thyroid gland	2	Medium
Tonsil	2	Medium
Urinary bladder	2	Medium
Vagina	1	Low

Summary
Symbol	ZMYND8
Name	zinc finger MYND-type containing 8
Aliases	RACK7; PRKCBP1; protein kinase C binding protein 1; PRO2893; CTCL tumor antigen se14-3; cutaneous T-cell lym ......
Location	20q13.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.143	NS	24476821
BRCA	Breast invasive carcinoma	521	5.84e-23	Significant	23000897
COAD	Colon adenocarcinoma	149	9.58e-14	Significant	22810696
GBM	Glioblastoma multiforme	157	0.00111	Significant	26824661
HNSC	Head and Neck squamous cell carcinoma	279	6.54e-05	Significant	25631445
KIRP	Kidney renal papillary cell carcinoma	161	0.0241	Significant	26536169
LGG	Brain Lower Grade Glioma	513	0.029	Significant	26824661
LUAD	Lung adenocarcinoma	230	0.0798	NS	25079552
LUSC	Lung squamous cell carcinoma	178	0.000361	Significant	22960745
OV	Ovarian serous cystadenocarcinoma	287	0.0171	Significant	21720365
PRAD	Prostate adenocarcinoma	333	7.56e-15	Significant	26544944
READ	Rectum adenocarcinoma	67	0.00411	Significant	22810696
SKCM	Skin Cutaneous Melanoma	315	0.00255	Significant	26091043
STAD	Stomach adenocarcinoma	277	5.87e-13	Significant	25079317
THCA	Thyroid carcinoma	391	1.15e-11	Significant	25417114
UCEC	Uterine Corpus Endometrial Carcinoma	232	0.00625	Significant	23636398

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	0.694	0.0872	NS
BRCA	Breast invasive carcinoma	1079	1.837	0.00686	Shorter
CESC	Cervical and endocervical cancers	291	1.56	0.166	NS
COAD	Colon adenocarcinoma	439	1.168	0.574	NS
ESCA	Esophageal carcinoma	184	2.036	0.0473	Shorter
GBM	Glioblastoma multiforme	158	0.905	0.689	NS
HNSC	Head and Neck squamous cell carcinoma	518	0.944	0.768	NS
KIRC	Kidney renal clear cell carcinoma	531	1.741	0.00561	Shorter
KIRP	Kidney renal papillary cell carcinoma	287	1.399	0.408	NS
LAML	Acute Myeloid Leukemia	149	1.002	0.991	NS
LGG	Brain Lower Grade Glioma	511	1.617	0.0525	NS
LIHC	Liver hepatocellular carcinoma	365	1.519	0.0876	NS
LUAD	Lung adenocarcinoma	502	1.03	0.894	NS
LUSC	Lung squamous cell carcinoma	494	1.177	0.401	NS
OV	Ovarian serous cystadenocarcinoma	303	1.066	0.767	NS
PAAD	Pancreatic adenocarcinoma	177	0.991	0.976	NS
PCPG	Pheochromocytoma and Paraganglioma	179	3.378	0.263	NS
PRAD	Prostate adenocarcinoma	497	0.849	0.841	NS
READ	Rectum adenocarcinoma	159	0.811	0.712	NS
SARC	Sarcoma	259	0.696	0.188	NS
SKCM	Skin Cutaneous Melanoma	459	0.962	0.848	NS
STAD	Stomach adenocarcinoma	388	0.885	0.582	NS
TGCT	Testicular Germ Cell Tumors	134	1591916549.882	0.16	NS
THCA	Thyroid carcinoma	500	1.122	0.88	NS
THYM	Thymoma	119	0.412	0.43	NS
UCEC	Uterine Corpus Endometrial Carcinoma	543	0.859	0.596	NS

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	-0.137	0.00552	Lower
BRCA	Breast invasive carcinoma	1071	0.061	0.0458	Higher
CESC	Cervical and endocervical cancers	167	0.139	0.0731	NS
COAD	Colon adenocarcinoma	445	0.124	0.00904	Higher
ESCA	Esophageal carcinoma	162	0.174	0.0269	Higher
HNSC	Head and Neck squamous cell carcinoma	448	0.025	0.597	NS
KIRC	Kidney renal clear cell carcinoma	531	0.148	0.000606	Higher
KIRP	Kidney renal papillary cell carcinoma	260	0.137	0.027	Higher
LIHC	Liver hepatocellular carcinoma	347	0.224	2.46e-05	Higher
LUAD	Lung adenocarcinoma	507	0.002	0.969	NS
LUSC	Lung squamous cell carcinoma	497	-0.045	0.319	NS
OV	Ovarian serous cystadenocarcinoma	302	-0.058	0.313	NS
PAAD	Pancreatic adenocarcinoma	176	-0.113	0.134	NS
READ	Rectum adenocarcinoma	156	0.051	0.529	NS
SKCM	Skin Cutaneous Melanoma	410	-0.024	0.634	NS
STAD	Stomach adenocarcinoma	392	0.04	0.435	NS
TGCT	Testicular Germ Cell Tumors	81	0.344	0.00167	Higher
THCA	Thyroid carcinoma	499	0.024	0.59	NS
UCEC	Uterine Corpus Endometrial Carcinoma	501	-0.075	0.0942	NS

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
CESC	Cervical and endocervical cancers	272	-0.004	0.941	NS
HNSC	Head and Neck squamous cell carcinoma	498	0.009	0.848	NS
KIRC	Kidney renal clear cell carcinoma	525	0.182	2.68e-05	Higher
LGG	Brain Lower Grade Glioma	514	0.078	0.0775	NS
LIHC	Liver hepatocellular carcinoma	366	0.106	0.0428	Higher
OV	Ovarian serous cystadenocarcinoma	296	0.072	0.219	NS
PAAD	Pancreatic adenocarcinoma	176	0.002	0.982	NS
STAD	Stomach adenocarcinoma	406	-0.154	0.0019	Lower
UCEC	Uterine Corpus Endometrial Carcinoma	534	-0.224	1.65e-07	Lower

Summary
Symbol	ZMYND8
Name	zinc finger MYND-type containing 8
Aliases	RACK7; PRKCBP1; protein kinase C binding protein 1; PRO2893; CTCL tumor antigen se14-3; cutaneous T-cell lym ......
Location	20q13.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	ZMYND8
Name	zinc finger MYND-type containing 8
Aliases	RACK7; PRKCBP1; protein kinase C binding protein 1; PRO2893; CTCL tumor antigen se14-3; cutaneous T-cell lym ......
Location	20q13.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for ZMYND8.

Summary
Symbol	ZMYND8
Name	zinc finger MYND-type containing 8
Aliases	RACK7; PRKCBP1; protein kinase C binding protein 1; PRO2893; CTCL tumor antigen se14-3; cutaneous T-cell lym ......
Location	20q13.12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining

[ TOP ]

PMID	Cancer	Hierarchy	Gene	Relation to CR	Evidence
23667654	Acute Erythroid Leukemia	partner	RELA	Fusion	A ZMYND8-RELA fusion was ranked first.
25117453	Prostate Carcinoma	downstream	Vegfa	positive regulation	Notably, ZMYND8 induced vegfa mRNA expression selectively in prostate cancer xenografts.