Visible node/edge number:
Node colors:
Node labels:

show label of nodes with degree >=

Node sizes:
Edge colors:
Edge widths factor:
Layout:

gravity >=

edgeLength =

GRN in network:

Notice: IE browser need to manually refresh (F5) this page after resetting the network.

This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-let-7a-3p ABCA1 -0.07 0.92099 -0.11 0.8728 mirMAP; miRNATAP -0.39 0 NA
2 hsa-let-7a-3p ABCC9 -0.07 0.92099 0.17 0.63712 mirMAP -0.8 0 NA
3 hsa-let-7a-3p ABCD2 -0.07 0.92099 -0.13 0.76186 mirMAP -0.51 5.0E-5 NA
4 hsa-miR-125a-5p ABHD3 0.06 0.95785 -0.09 0.90386 PITA; miRanda -0.19 0.00818 NA
5 hsa-let-7a-3p ABI3BP -0.07 0.92099 -0.37 0.41633 miRNATAP -0.62 2.0E-5 NA
6 hsa-miR-15a-5p ABL2 0.11 0.90237 0.04 0.95748 MirTarget; miRNATAP -0.16 5.0E-5 NA
7 hsa-miR-125a-5p ACPP 0.06 0.95785 -0.43 0.34039 MirTarget; miRanda -0.36 0.02701 NA
8 hsa-miR-125a-5p ACTL6A 0.06 0.95785 0.05 0.95251 miRanda -0.12 0.00186 NA
9 hsa-let-7a-3p ACVR1 -0.07 0.92099 -0.02 0.98204 MirTarget; miRNATAP -0.12 0.00024 NA
10 hsa-miR-125a-5p ADAM10 0.06 0.95785 -0.21 0.80651 miRanda -0.11 0.04343 NA
11 hsa-let-7a-3p ADAM23 -0.07 0.92099 -0.36 0.37035 mirMAP -0.96 0 NA
12 hsa-miR-15a-5p ADAMTS18 0.11 0.90237 -0.6 0.24444 miRNATAP -1 0 NA
13 hsa-miR-15a-5p ADAMTS3 0.11 0.90237 -0.15 0.57772 miRNATAP -0.59 0 NA
14 hsa-let-7a-3p ADAMTS5 -0.07 0.92099 0.35 0.38267 mirMAP -0.36 0 NA
15 hsa-miR-15a-5p ADAMTS5 0.11 0.90237 0.35 0.38267 miRNATAP -0.39 0 NA
16 hsa-let-7a-3p ADAMTSL3 -0.07 0.92099 -0.2 0.64161 MirTarget -1.14 0 NA
17 hsa-miR-15a-5p ADAMTSL3 0.11 0.90237 -0.2 0.64161 MirTarget -1.46 0 NA
18 hsa-miR-15a-5p ADCY1 0.11 0.90237 0.38 0.25371 mirMAP -0.32 0.01019 NA
19 hsa-miR-15a-5p ADCY5 0.11 0.90237 -0.55 0.2334 MirTarget; miRNATAP -1.61 0 NA
20 hsa-let-7a-3p ADCYAP1 -0.07 0.92099 0.13 0.79662 miRNATAP -1.12 0 NA
21 hsa-let-7a-3p ADD2 -0.07 0.92099 -0.16 0.76694 mirMAP -0.74 0 NA
22 hsa-miR-125a-5p ADH5 0.06 0.95785 0.01 0.99261 miRanda -0.12 0.0022 NA
23 hsa-miR-15a-5p ADRB2 0.11 0.90237 -0.01 0.98489 MirTarget -0.79 0 NA
24 hsa-let-7a-3p AFF2 -0.07 0.92099 -0.3 0.56096 mirMAP -0.35 0.012 NA
25 hsa-let-7a-3p AFF3 -0.07 0.92099 -0.5 0.15768 MirTarget -0.46 0.00048 NA
26 hsa-miR-15a-5p AFF4 0.11 0.90237 -0.1 0.9096 MirTarget; miRNATAP -0.11 0.00251 NA
27 hsa-miR-15a-5p AGPAT4 0.11 0.90237 0.33 0.44742 mirMAP -0.46 2.0E-5 NA
28 hsa-let-7a-3p AKAP12 -0.07 0.92099 0.17 0.82172 miRNATAP -0.88 0 NA
29 hsa-miR-15a-5p AKT3 0.11 0.90237 0.06 0.90908 miRNAWalker2 validate; miRTarBase; miRNATAP -0.72 0 NA
30 hsa-let-7a-3p ALDH1L2 -0.07 0.92099 0.28 0.55075 MirTarget -0.5 0 NA
31 hsa-miR-125a-5p ALDH6A1 0.06 0.95785 -0.27 0.59927 miRanda -0.22 0.00306 NA
32 hsa-let-7a-3p AMIGO2 -0.07 0.92099 0.21 0.75965 MirTarget; mirMAP -0.39 5.0E-5 NA
33 hsa-let-7a-3p AMOTL1 -0.07 0.92099 -0.11 0.85689 mirMAP -0.64 0 NA
34 hsa-miR-15a-5p AMOTL1 0.11 0.90237 -0.11 0.85689 MirTarget; miRNATAP -0.94 0 NA
35 hsa-miR-125a-5p ANGPT2 0.06 0.95785 0.03 0.95669 miRanda -0.19 0.01088 NA
36 hsa-miR-15a-5p ANK2 0.11 0.90237 0.04 0.93166 MirTarget; miRNATAP -1.21 0 NA
37 hsa-miR-15a-5p ANKRD29 0.11 0.90237 0.28 0.38764 MirTarget -0.39 0.00308 NA
38 hsa-let-7a-3p ANKRD50 -0.07 0.92099 -0.1 0.88159 mirMAP -0.19 4.0E-5 NA
39 hsa-miR-125a-5p ANKS1A 0.06 0.95785 -0.12 0.88556 miRanda -0.11 0.00232 NA
40 hsa-let-7a-3p ANO5 -0.07 0.92099 0.58 0.27012 mirMAP -0.59 0.00256 NA
41 hsa-miR-125a-5p ANP32A 0.06 0.95785 -0.06 0.95269 miRanda -0.11 0.003 NA
42 hsa-let-7a-3p ANTXR1 -0.07 0.92099 -0.05 0.96265 mirMAP; miRNATAP -0.79 0 NA
43 hsa-miR-125a-5p API5 0.06 0.95785 -0.01 0.99409 miRanda -0.13 3.0E-5 NA
44 hsa-miR-15a-5p APLNR 0.11 0.90237 0.01 0.99326 MirTarget -0.35 0.00048 NA
45 hsa-miR-15a-5p APP 0.11 0.90237 -0.18 0.89833 miRNAWalker2 validate; miRNATAP -0.14 0.00073 NA
46 hsa-let-7a-3p AQP9 -0.07 0.92099 0.18 0.73115 MirTarget -0.89 0 NA
47 hsa-miR-15a-5p AR 0.11 0.90237 -0.54 0.32591 mirMAP; miRNATAP -1.06 0 NA
48 hsa-miR-125a-5p ARHGAP11B 0.06 0.95785 -0.31 0.23724 miRanda -0.19 0.01801 NA
49 hsa-let-7a-3p ARHGAP20 -0.07 0.92099 0.1 0.77766 MirTarget; miRNATAP -0.61 0 NA
50 hsa-miR-15a-5p ARHGAP20 0.11 0.90237 0.1 0.77766 MirTarget; miRNATAP -0.85 0 NA
51 hsa-let-7a-3p ARHGAP28 -0.07 0.92099 -0.23 0.43033 mirMAP -0.39 0.00025 NA
52 hsa-let-7a-3p ARHGAP29 -0.07 0.92099 0.16 0.78525 mirMAP -0.27 0.00025 NA
53 hsa-miR-125a-5p ARID4A 0.06 0.95785 -0.06 0.92409 miRanda -0.12 0.00166 NA
54 hsa-let-7a-3p ARL10 -0.07 0.92099 -0.24 0.42733 mirMAP -0.55 0 NA
55 hsa-miR-15a-5p ARL2 0.11 0.90237 0.02 0.97901 MirTarget; miRNATAP -0.11 0.01332 NA
56 hsa-miR-15a-5p ARMCX2 0.11 0.90237 0.29 0.5542 MirTarget; miRNATAP -0.57 0 NA
57 hsa-miR-15a-5p ARNT2 0.11 0.90237 -0.47 0.3134 mirMAP -0.78 0 NA
58 hsa-let-7a-3p ARSB -0.07 0.92099 -0.08 0.88514 mirMAP -0.17 0.00258 NA
59 hsa-let-7a-3p ASAH1 -0.07 0.92099 -0.05 0.96217 MirTarget -0.14 0.00225 NA
60 hsa-let-7a-3p ASAP1 -0.07 0.92099 -0.09 0.91083 mirMAP -0.19 0.0006 NA
61 hsa-miR-15a-5p ASH1L 0.11 0.90237 -0.14 0.87278 MirTarget; miRNATAP -0.12 0.00706 NA
62 hsa-miR-15a-5p ASTN1 0.11 0.90237 0.05 0.94222 MirTarget -1.25 0 NA
63 hsa-let-7a-3p ASXL2 -0.07 0.92099 -0.3 0.6827 mirMAP; miRNATAP -0.18 0.00081 NA
64 hsa-miR-15a-5p ASXL2 0.11 0.90237 -0.3 0.6827 miRNAWalker2 validate -0.13 0.03086 NA
65 hsa-let-7a-3p ATE1 -0.07 0.92099 -0.24 0.65828 mirMAP -0.13 0.00265 NA
66 hsa-let-7a-3p ATF2 -0.07 0.92099 -0.24 0.68896 MirTarget; mirMAP; miRNATAP -0.15 4.0E-5 NA
67 hsa-miR-15a-5p ATF2 0.11 0.90237 -0.24 0.68896 miRNAWalker2 validate -0.12 0.00218 NA
68 hsa-miR-125a-5p ATL2 0.06 0.95785 -0.06 0.94297 miRNAWalker2 validate; miRanda -0.12 0.00034 NA
69 hsa-let-7a-3p ATP6AP2 -0.07 0.92099 -0.05 0.96232 mirMAP -0.13 0.00027 NA
70 hsa-let-7a-3p ATRN -0.07 0.92099 -0.46 0.56279 miRNATAP -0.26 8.0E-5 NA
71 hsa-let-7a-3p ATRX -0.07 0.92099 -0.24 0.77958 MirTarget; miRNATAP -0.13 0.00051 NA
72 hsa-miR-15a-5p ATXN1L 0.11 0.90237 -0.14 0.85841 miRNATAP -0.11 0.00148 NA
73 hsa-let-7a-3p B3GALNT1 -0.07 0.92099 0.4 0.30968 mirMAP -0.37 0.00031 NA
74 hsa-miR-15a-5p BACE1 0.11 0.90237 -0.16 0.82465 miRNAWalker2 validate; miRNATAP -0.33 0 NA
75 hsa-miR-15a-5p BACH2 0.11 0.90237 -0.35 0.26727 MirTarget; miRNATAP -0.78 0 NA
76 hsa-let-7a-3p BAG4 -0.07 0.92099 -0.21 0.6077 mirMAP -0.2 0.00021 NA
77 hsa-miR-125a-5p BAG4 0.06 0.95785 -0.21 0.6077 MirTarget -0.17 0.00683 NA
78 hsa-miR-125a-5p BAK1 0.06 0.95785 0.22 0.78301 miRNAWalker2 validate; PITA; miRanda; miRNATAP -0.18 0.0026 NA
79 hsa-let-7a-3p BASP1 -0.07 0.92099 0.06 0.91132 miRNATAP -0.46 0 NA
80 hsa-miR-125a-5p BATF2 0.06 0.95785 -0.01 0.99363 miRanda -0.18 0.04948 NA
81 hsa-miR-125a-5p BAZ1A 0.06 0.95785 -0.03 0.97529 miRanda -0.15 0.00012 NA
82 hsa-miR-15a-5p BCL2 0.11 0.90237 -0.44 0.34621 miRNAWalker2 validate; miRTarBase -0.22 0.02911 25623762; 25594541; 26915294; 18931683; 22335947 miR 15a and miR 16 modulate drug resistance by targeting bcl 2 in human colon cancer cells; To investigate the reversal effect of targeted modulation of bcl-2 expression by miR-15a and miR-16 on drug resistance of human colon cancer cells;MicroRNAs miRNAs encoded by the miR-15 cluster are known to induce G1 arrest and apoptosis by targeting G1 checkpoints and the anti-apoptotic B cell lymphoma 2 BCL-2 gene;As a result transcript levels of the tumor-suppressive miR-15 and let-7 families increased which targeted and decreased the expression of the crucial prosurvival genes BCL-2 and BCL-XL respectively;MicroRNAs miRNAs are noncoding small RNAs that repress protein translation by targeting specific messenger RNAs miR-15a and miR-16-1 act as putative tumor suppressors by targeting the oncogene BCL2;The expression of MiR-15a was significantly inhibited by Bcl-2 P < 0.05
83 hsa-miR-125a-5p BCL2L14 0.06 0.95785 -0.05 0.93549 MirTarget; PITA; miRanda -0.16 0.04212 NA
84 hsa-miR-15a-5p BCL2L2 0.11 0.90237 0 0.99812 MirTarget; miRNATAP -0.14 0.00012 25874488 MicroRNA 15a induces cell apoptosis and inhibits metastasis by targeting BCL2L2 in non small cell lung cancer; Furthermore we identified that BCL2L2 was a target of miR-15a and negatively regulated by miR-15a at the translational level; miR-15a acts as a tumor suppressor in NSCLC by directly targeting BCL2L2 and may serve as a potential diagnostic biomarker and therapeutic target for NSCLC
85 hsa-let-7a-3p BCL6 -0.07 0.92099 -0.02 0.97924 miRNATAP -0.17 0.00802 NA
86 hsa-let-7a-3p BDNF -0.07 0.92099 -0.01 0.97997 MirTarget; miRNATAP -0.24 0.00935 NA
87 hsa-miR-15a-5p BDNF 0.11 0.90237 -0.01 0.97997 MirTarget; miRNATAP -0.36 0.00046 26581909 MicroRNA 15a 5p suppresses cancer proliferation and division in human hepatocellular carcinoma by targeting BDNF; BDNF was then overexpressed in HepG2 and SNU-182 cells to evaluate its selective effect on miR-15a-5p in HCC modulation; MiR-15a-5p selectively and negatively regulated BDNF at both gene and protein levels in HCC cells; Forced overexpression of BDNF effectively reversed the tumor suppressive functions of miR-15a-5p on HCC proliferation and cell division in vitro; Our study demonstrated that miR-15a-5p is a tumor suppressor in HCC and its regulation is through BDNF in HCC
88 hsa-let-7a-3p BEND4 -0.07 0.92099 0.03 0.96594 mirMAP -0.41 0.00473 NA
89 hsa-let-7a-3p BEND6 -0.07 0.92099 0.06 0.87652 mirMAP -0.77 0 NA
90 hsa-miR-15a-5p BHLHE41 0.11 0.90237 0.27 0.66334 miRNATAP -0.38 0.00052 NA
91 hsa-let-7a-3p BICD2 -0.07 0.92099 -0.05 0.94512 mirMAP -0.1 0.00472 NA
92 hsa-miR-125a-5p BIK 0.06 0.95785 0.15 0.80372 miRanda -0.21 0.04414 NA
93 hsa-let-7a-3p BMP2K -0.07 0.92099 -0.19 0.72063 mirMAP -0.17 6.0E-5 NA
94 hsa-let-7a-3p BMP3 -0.07 0.92099 -0.26 0.66775 MirTarget; mirMAP -0.82 0.00029 NA
95 hsa-let-7a-3p BMPR1B -0.07 0.92099 -0.25 0.60455 miRNATAP -0.61 0.00028 NA
96 hsa-let-7a-3p BMPR2 -0.07 0.92099 -0.17 0.84777 MirTarget; miRNATAP -0.18 0.00013 NA
97 hsa-miR-15a-5p BMX 0.11 0.90237 -0.01 0.97533 MirTarget; miRNATAP -0.82 0 NA
98 hsa-let-7a-3p BNC2 -0.07 0.92099 -0.03 0.94679 mirMAP -0.77 0 NA
99 hsa-miR-125a-5p BRCC3 0.06 0.95785 -0.17 0.83954 miRanda -0.13 0.01416 NA
100 hsa-miR-125a-5p BRPF3 0.06 0.95785 -0.19 0.82481 MirTarget -0.13 0.0056 NA
101 hsa-let-7a-3p BST1 -0.07 0.92099 0.23 0.52012 MirTarget -0.38 0.00024 NA
102 hsa-miR-15a-5p BTBD19 0.11 0.90237 0.16 0.58395 mirMAP -0.42 7.0E-5 NA
103 hsa-let-7a-3p BTC -0.07 0.92099 -0.19 0.42376 mirMAP -0.2 0.00283 NA
104 hsa-miR-125a-5p BTC 0.06 0.95785 -0.19 0.42376 miRanda -0.16 0.04529 NA
105 hsa-miR-15a-5p BTG2 0.11 0.90237 0.01 0.99517 MirTarget; miRNATAP -0.17 0.00744 NA
106 hsa-let-7a-3p BVES -0.07 0.92099 0.04 0.90028 mirMAP -0.64 0 NA
107 hsa-miR-15a-5p BVES 0.11 0.90237 0.04 0.90028 MirTarget -1.02 0 NA
108 hsa-let-7a-3p CACNA1C -0.07 0.92099 -0.15 0.80484 MirTarget -0.23 0.03112 NA
109 hsa-miR-15a-5p CACNA1E 0.11 0.90237 0.16 0.74358 MirTarget -0.85 0 NA
110 hsa-let-7a-3p CACNA2D1 -0.07 0.92099 -0.25 0.60439 mirMAP -1.24 0 NA
111 hsa-miR-15a-5p CACNB4 0.11 0.90237 0.17 0.63328 miRNATAP -0.51 9.0E-5 NA
112 hsa-let-7a-3p CACNG4 -0.07 0.92099 -0.11 0.86743 MirTarget -0.55 0.03405 NA
113 hsa-miR-15a-5p CADM1 0.11 0.90237 0.14 0.76681 miRNAWalker2 validate; miRTarBase; miRNATAP -0.83 0 NA
114 hsa-miR-15a-5p CALD1 0.11 0.90237 0.1 0.9298 miRNAWalker2 validate -0.9 0 NA
115 hsa-miR-15a-5p CALU 0.11 0.90237 0.06 0.9593 MirTarget -0.22 0 NA
116 hsa-miR-125a-5p CANT1 0.06 0.95785 0.06 0.95485 mirMAP -0.12 0.04622 NA
117 hsa-miR-15a-5p CAPN6 0.11 0.90237 0.87 0.21395 miRNATAP -1.14 1.0E-5 NA
118 hsa-miR-125a-5p CAPZA2 0.06 0.95785 -0.02 0.98174 miRanda -0.1 0.02005 NA
119 hsa-miR-15a-5p CARD8 0.11 0.90237 0.12 0.83502 miRNAWalker2 validate -0.18 2.0E-5 NA
120 hsa-miR-125a-5p CASP6 0.06 0.95785 -0.09 0.9061 miRanda -0.13 0.02252 NA
121 hsa-let-7a-3p CCDC102B -0.07 0.92099 0.33 0.16371 MirTarget -0.29 0.00016 NA
122 hsa-let-7a-3p CCDC50 -0.07 0.92099 0.08 0.92311 miRNATAP -0.14 0 NA
123 hsa-miR-125a-5p CCNC 0.06 0.95785 -0.05 0.95565 miRanda -0.16 0.00022 NA
124 hsa-miR-15a-5p CCND1 0.11 0.90237 -0.18 0.87202 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.13 0.01564 22922827 CCND1 has been found to be a target of miR-15a and miR-16-1 through analysis of complementary sequences between microRNAs and CCND1 mRNA; Moreover the transcription of CCND1 is suppressed by miR-15a and miR-16-1 via direct binding to the CCND1 3'-untranslated region 3'-UTR
125 hsa-miR-125a-5p CCNJ 0.06 0.95785 -0.09 0.87726 MirTarget; PITA; miRanda; miRNATAP -0.1 0.02175 NA
126 hsa-miR-15a-5p CCNJL 0.11 0.90237 -0.5 0.32399 miRNATAP -0.22 0.04258 NA
127 hsa-let-7a-3p CCPG1 -0.07 0.92099 0.07 0.93571 mirMAP -0.18 0.00016 NA
128 hsa-miR-125a-5p CCT2 0.06 0.95785 0.01 0.99233 miRanda -0.11 0.01193 NA
129 hsa-let-7a-3p CD109 -0.07 0.92099 0.31 0.60219 mirMAP -0.58 7.0E-5 NA
130 hsa-miR-15a-5p CD28 0.11 0.90237 -0.11 0.71453 MirTarget; miRNATAP -0.26 0.03384 NA
131 hsa-let-7a-3p CD302 -0.07 0.92099 -0.02 0.97427 mirMAP -0.17 0.00116 NA
132 hsa-let-7a-3p CD38 -0.07 0.92099 0.36 0.40643 MirTarget -0.66 4.0E-5 NA
133 hsa-let-7a-3p CDC14A -0.07 0.92099 -0.08 0.8497 mirMAP -0.15 0.00458 NA
134 hsa-miR-125a-5p CDC14C 0.06 0.95785 -0.06 0.82588 miRanda -0.24 0.00202 NA
135 hsa-miR-125a-5p CDC23 0.06 0.95785 -0.02 0.98133 miRanda -0.1 0.00117 NA
136 hsa-let-7a-3p CDC42EP3 -0.07 0.92099 0 0.99642 MirTarget; mirMAP -0.25 3.0E-5 NA
137 hsa-let-7a-3p CDK17 -0.07 0.92099 -0.03 0.96173 MirTarget; miRNATAP -0.12 0.00022 NA
138 hsa-miR-15a-5p CDK17 0.11 0.90237 -0.03 0.96173 MirTarget; miRNATAP -0.17 0 NA
139 hsa-let-7a-3p CDS2 -0.07 0.92099 -0.27 0.71103 mirMAP -0.12 0.00961 NA
140 hsa-miR-15a-5p CDS2 0.11 0.90237 -0.27 0.71103 mirMAP; miRNATAP -0.25 0 NA
141 hsa-miR-15a-5p CECR6 0.11 0.90237 -0.51 0.04771 MirTarget; miRNATAP -0.2 0.03797 NA
142 hsa-miR-125a-5p CENPO 0.06 0.95785 -0.07 0.87469 mirMAP -0.13 0.00452 NA
143 hsa-miR-125a-5p CES3 0.06 0.95785 0.23 0.73891 miRanda -0.37 0.02945 NA
144 hsa-let-7a-3p CFL2 -0.07 0.92099 -0 0.9933 mirMAP -0.42 0 NA
145 hsa-miR-15a-5p CHD5 0.11 0.90237 0.26 0.55655 miRNATAP -0.46 0.0018 NA
146 hsa-miR-15a-5p CHD9 0.11 0.90237 -0.09 0.90367 miRNATAP -0.2 1.0E-5 NA
147 hsa-let-7a-3p CHL1 -0.07 0.92099 -0.21 0.62739 MirTarget; miRNATAP -0.94 0 NA
148 hsa-let-7a-3p CHM -0.07 0.92099 -0.21 0.75281 MirTarget -0.13 0.00246 NA
149 hsa-let-7a-3p CHST2 -0.07 0.92099 0.09 0.79889 MirTarget -0.3 0.0002 NA
150 hsa-miR-125a-5p CKS1B 0.06 0.95785 0.14 0.85897 miRanda -0.1 0.0406 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 NEUROGENESIS 137 1402 1.608e-19 3.742e-16
2 CELL DEVELOPMENT 139 1426 1.037e-19 3.742e-16
3 CARDIOVASCULAR SYSTEM DEVELOPMENT 94 788 4.632e-19 5.388e-16
4 CIRCULATORY SYSTEM DEVELOPMENT 94 788 4.632e-19 5.388e-16
5 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 152 1672 1.088e-18 1.013e-15
6 REGULATION OF CELL DEVELOPMENT 94 836 2.391e-17 1.854e-14
7 REGULATION OF CELL DIFFERENTIATION 137 1492 3.389e-17 2.253e-14
8 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 122 1275 1.091e-16 6.346e-14
9 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 103 1021 1.119e-15 5.207e-13
10 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 111 1142 1.064e-15 5.207e-13
11 CELLULAR COMPONENT MORPHOGENESIS 94 900 2.67e-15 1.13e-12
12 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 82 750 1.493e-14 5.789e-12
13 NEURON DIFFERENTIATION 90 874 2.559e-14 9.158e-12
14 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 64 513 3.473e-14 1.154e-11
15 CENTRAL NERVOUS SYSTEM DEVELOPMENT 89 872 6.05e-14 1.877e-11
16 REGULATION OF CELLULAR COMPONENT MOVEMENT 82 771 6.886e-14 2.002e-11
17 VASCULATURE DEVELOPMENT 60 469 7.427e-14 2.033e-11
18 TISSUE DEVELOPMENT 128 1518 2.677e-13 6.921e-11
19 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 120 1395 4.337e-13 1.062e-10
20 RESPONSE TO ENDOGENOUS STIMULUS 123 1450 5.597e-13 1.302e-10
21 BLOOD VESSEL MORPHOGENESIS 50 364 6.396e-13 1.353e-10
22 HEART DEVELOPMENT 58 466 6.367e-13 1.353e-10
23 LOCOMOTION 102 1114 7.556e-13 1.529e-10
24 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 91 957 1.832e-12 3.279e-10
25 REGULATION OF DEVELOPMENTAL GROWTH 43 289 1.826e-12 3.279e-10
26 NEURON PROJECTION DEVELOPMENT 63 545 1.75e-12 3.279e-10
27 POSITIVE REGULATION OF CELL DIFFERENTIATION 82 823 2.275e-12 3.92e-10
28 ORGAN MORPHOGENESIS 83 841 2.731e-12 4.538e-10
29 HEAD DEVELOPMENT 74 709 3.121e-12 5.007e-10
30 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 72 689 5.892e-12 9.138e-10
31 TUBE DEVELOPMENT 62 552 9.147e-12 1.373e-09
32 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 79 801 9.855e-12 1.433e-09
33 MESENCHYME DEVELOPMENT 33 190 1.028e-11 1.45e-09
34 MUSCLE STRUCTURE DEVELOPMENT 53 432 1.13e-11 1.546e-09
35 POSITIVE REGULATION OF LOCOMOTION 52 420 1.258e-11 1.672e-09
36 NEURON DEVELOPMENT 71 687 1.396e-11 1.804e-09
37 REGULATION OF NEURON DIFFERENTIATION 61 554 3.107e-11 3.907e-09
38 CELL PROJECTION ORGANIZATION 83 902 9.811e-11 1.201e-08
39 POSITIVE REGULATION OF CELL DEVELOPMENT 54 472 1.051e-10 1.254e-08
40 MESENCHYMAL CELL DIFFERENTIATION 26 134 1.295e-10 1.506e-08
41 RESPONSE TO GROWTH FACTOR 54 475 1.333e-10 1.513e-08
42 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 89 1008 1.695e-10 1.877e-08
43 NEGATIVE REGULATION OF CELL DIFFERENTIATION 63 609 2e-10 2.165e-08
44 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 127 1656 2.135e-10 2.18e-08
45 HEART MORPHOGENESIS 33 212 2.109e-10 2.18e-08
46 REGULATION OF CELL MORPHOGENESIS 59 552 2.156e-10 2.18e-08
47 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 134 1784 2.499e-10 2.474e-08
48 REGULATION OF CELL DEATH 116 1472 2.914e-10 2.825e-08
49 PROTEIN PHOSPHORYLATION 84 944 3.951e-10 3.751e-08
50 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 50 437 5.231e-10 4.868e-08
51 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 143 1977 7.564e-10 6.901e-08
52 STEM CELL DIFFERENTIATION 30 190 9.841e-10 8.806e-08
53 TISSUE MORPHOGENESIS 56 533 1.189e-09 1.044e-07
54 REGULATION OF MEMBRANE POTENTIAL 42 343 1.701e-09 1.466e-07
55 INTRACELLULAR SIGNAL TRANSDUCTION 119 1572 1.89e-09 1.599e-07
56 REGULATION OF GROWTH 62 633 2.443e-09 2.016e-07
57 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 134 1848 2.47e-09 2.016e-07
58 BEHAVIOR 54 516 2.726e-09 2.15e-07
59 BIOLOGICAL ADHESION 87 1032 2.692e-09 2.15e-07
60 REGULATION OF PHOSPHORUS METABOLIC PROCESS 121 1618 2.795e-09 2.168e-07
61 TUBE MORPHOGENESIS 40 323 2.998e-09 2.287e-07
62 NEGATIVE REGULATION OF CELL DEATH 77 872 3.149e-09 2.363e-07
63 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 41 337 3.221e-09 2.379e-07
64 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 131 1805 3.648e-09 2.652e-07
65 REGULATION OF SYSTEM PROCESS 53 507 3.985e-09 2.809e-07
66 MUSCLE CELL DIFFERENTIATION 33 237 3.935e-09 2.809e-07
67 REGULATION OF CELL ADHESION 61 629 4.813e-09 3.343e-07
68 POSITIVE REGULATION OF CELL COMMUNICATION 115 1532 5.944e-09 3.951e-07
69 SKELETAL SYSTEM DEVELOPMENT 49 455 5.92e-09 3.951e-07
70 REGULATION OF CELL PROLIFERATION 113 1496 5.809e-09 3.951e-07
71 REGULATION OF CELL PROJECTION ORGANIZATION 56 558 6.269e-09 4.108e-07
72 ANGIOGENESIS 37 293 6.912e-09 4.467e-07
73 ACTIN FILAMENT BASED PROCESS 48 450 1.152e-08 7.342e-07
74 UROGENITAL SYSTEM DEVELOPMENT 37 299 1.197e-08 7.461e-07
75 REGULATION OF TRANSPORT 129 1804 1.203e-08 7.461e-07
76 CELL MOTILITY 73 835 1.256e-08 7.591e-07
77 LOCALIZATION OF CELL 73 835 1.256e-08 7.591e-07
78 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 104 1360 1.345e-08 8.024e-07
79 REGULATION OF STEM CELL DIFFERENTIATION 21 113 1.723e-08 1.015e-06
80 PHOSPHORYLATION 96 1228 1.776e-08 1.033e-06
81 EXTRACELLULAR STRUCTURE ORGANIZATION 37 304 1.867e-08 1.073e-06
82 MORPHOGENESIS OF AN EPITHELIUM 44 400 1.9e-08 1.078e-06
83 REGULATION OF PROTEIN MODIFICATION PROCESS 123 1710 1.993e-08 1.117e-06
84 EPITHELIUM DEVELOPMENT 79 945 2.198e-08 1.208e-06
85 POSITIVE REGULATION OF CELL PROLIFERATION 71 814 2.206e-08 1.208e-06
86 NEURON PROJECTION GUIDANCE 29 205 2.401e-08 1.299e-06
87 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 81 983 2.714e-08 1.451e-06
88 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 84 1036 3.038e-08 1.588e-06
89 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 84 1036 3.038e-08 1.588e-06
90 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 82 1004 3.269e-08 1.69e-06
91 REGULATION OF NEURON PROJECTION DEVELOPMENT 44 408 3.417e-08 1.747e-06
92 GROWTH 44 410 3.946e-08 1.996e-06
93 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 50 498 4.074e-08 2.038e-06
94 EMBRYO DEVELOPMENT 75 894 4.419e-08 2.187e-06
95 SINGLE ORGANISM BEHAVIOR 42 384 4.704e-08 2.304e-06
96 POSITIVE REGULATION OF RESPONSE TO STIMULUS 133 1929 6.124e-08 2.968e-06
97 NEURON PROJECTION MORPHOGENESIS 43 402 6.188e-08 2.968e-06
98 REGULATION OF OSSIFICATION 26 178 6.56e-08 3.115e-06
99 REGULATION OF POSTSYNAPTIC MEMBRANE POTENTIAL 14 55 6.831e-08 3.211e-06
100 RESPONSE TO LIPID 74 888 7.156e-08 3.302e-06
101 MORPHOGENESIS OF A BRANCHING STRUCTURE 25 167 7.169e-08 3.302e-06
102 SENSORY ORGAN DEVELOPMENT 49 493 7.633e-08 3.482e-06
103 TAXIS 47 464 8.001e-08 3.58e-06
104 EMBRYONIC MORPHOGENESIS 52 539 7.986e-08 3.58e-06
105 OUTFLOW TRACT MORPHOGENESIS 14 56 8.745e-08 3.875e-06
106 REGULATION OF EPITHELIAL CELL PROLIFERATION 34 285 1.145e-07 5.024e-06
107 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 40 368 1.162e-07 5.052e-06
108 CARDIAC SEPTUM DEVELOPMENT 17 85 1.289e-07 5.555e-06
109 REGULATION OF CYTOSKELETON ORGANIZATION 49 502 1.331e-07 5.682e-06
110 POSITIVE REGULATION OF GENE EXPRESSION 121 1733 1.365e-07 5.773e-06
111 REGULATION OF CELL SUBSTRATE ADHESION 25 173 1.447e-07 6.065e-06
112 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 63 724 1.54e-07 6.399e-06
113 MUSCLE ORGAN DEVELOPMENT 33 277 1.812e-07 7.462e-06
114 DEVELOPMENTAL GROWTH 37 333 1.992e-07 8.129e-06
115 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 88 1152 2.049e-07 8.289e-06
116 NEGATIVE REGULATION OF CELL COMMUNICATION 90 1192 2.468e-07 9.901e-06
117 POSITIVE REGULATION OF MOLECULAR FUNCTION 123 1791 2.588e-07 1.029e-05
118 CARDIAC CHAMBER DEVELOPMENT 22 144 3.009e-07 1.187e-05
119 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 23 156 3.141e-07 1.228e-05
120 SYNAPSE ORGANIZATION 22 145 3.403e-07 1.32e-05
121 APPENDAGE DEVELOPMENT 24 169 3.556e-07 1.356e-05
122 LIMB DEVELOPMENT 24 169 3.556e-07 1.356e-05
123 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 29 232 3.633e-07 1.372e-05
124 RESPONSE TO OXYGEN CONTAINING COMPOUND 100 1381 3.657e-07 1.372e-05
125 REGULATION OF KINASE ACTIVITY 65 776 3.85e-07 1.433e-05
126 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 18 103 4.691e-07 1.732e-05
127 CELL CELL SIGNALING 64 767 5.422e-07 1.987e-05
128 MEMBRANE DEPOLARIZATION DURING ACTION POTENTIAL 11 39 5.676e-07 2.047e-05
129 NEGATIVE CHEMOTAXIS 11 39 5.676e-07 2.047e-05
130 POSITIVE REGULATION OF NEURON DIFFERENTIATION 34 306 6.188e-07 2.212e-05
131 POSITIVE REGULATION OF GROWTH 29 238 6.227e-07 2.212e-05
132 CYTOSKELETON ORGANIZATION 68 838 6.545e-07 2.307e-05
133 NEURAL CREST CELL DIFFERENTIATION 15 75 7.039e-07 2.463e-05
134 REGULATION OF BLOOD CIRCULATION 33 295 7.749e-07 2.691e-05
135 REGULATION OF TRANSFERASE ACTIVITY 74 946 8.388e-07 2.891e-05
136 IMMUNE SYSTEM DEVELOPMENT 52 582 8.699e-07 2.976e-05
137 REGULATION OF ORGAN MORPHOGENESIS 29 242 8.815e-07 2.994e-05
138 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 14 67 9.425e-07 3.178e-05
139 REGULATION OF ACTIN FILAMENT BASED PROCESS 34 312 9.685e-07 3.242e-05
140 CELL PART MORPHOGENESIS 55 633 1.008e-06 3.352e-05
141 RESPONSE TO ORGANIC CYCLIC COMPOUND 72 917 1.036e-06 3.419e-05
142 FOREBRAIN DEVELOPMENT 37 357 1.11e-06 3.637e-05
143 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 58 684 1.121e-06 3.647e-05
144 REGULATION OF CELLULAR COMPONENT BIOGENESIS 63 767 1.138e-06 3.676e-05
145 NEURON MIGRATION 18 110 1.278e-06 4.101e-05
146 DENDRITE DEVELOPMENT 15 79 1.414e-06 4.446e-05
147 NEGATIVE REGULATION OF CELL DEVELOPMENT 33 303 1.413e-06 4.446e-05
148 MUSCLE TISSUE DEVELOPMENT 31 275 1.413e-06 4.446e-05
149 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 84 1135 1.437e-06 4.488e-05
150 NEURAL CREST CELL MIGRATION 12 51 1.479e-06 4.587e-05
151 RESPONSE TO HORMONE 70 893 1.561e-06 4.811e-05
152 REGULATION OF CELL MATRIX ADHESION 16 90 1.593e-06 4.876e-05
153 REGULATION OF EXTENT OF CELL GROWTH 17 101 1.675e-06 5.094e-05
154 MEMBRANE DEPOLARIZATION 13 61 1.816e-06 5.487e-05
155 REGULATION OF ORGANELLE ORGANIZATION 86 1178 1.858e-06 5.578e-05
156 REGULATION OF SYNAPSE ORGANIZATION 18 113 1.911e-06 5.701e-05
157 KIDNEY EPITHELIUM DEVELOPMENT 19 125 2.065e-06 6.119e-05
158 RETINA VASCULATURE DEVELOPMENT IN CAMERA TYPE EYE 7 16 2.404e-06 7.08e-05
159 CARDIAC CHAMBER MORPHOGENESIS 17 104 2.545e-06 7.448e-05
160 ACTION POTENTIAL 16 94 2.892e-06 8.411e-05
161 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 60 740 3.108e-06 8.981e-05
162 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 15 84 3.169e-06 9.046e-05
163 POSITIVE REGULATION OF OSSIFICATION 15 84 3.169e-06 9.046e-05
164 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 18 117 3.194e-06 9.063e-05
165 REGULATION OF EPITHELIAL CELL MIGRATION 22 166 3.498e-06 9.864e-05
166 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 102 1492 3.782e-06 0.000106
167 REGULATION OF HYDROLASE ACTIVITY 93 1327 3.861e-06 0.0001076
168 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 19 131 4.215e-06 0.0001167
169 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 20 144 4.679e-06 0.0001288
170 REGULATION OF AXON GUIDANCE 10 39 4.831e-06 0.0001322
171 CELLULAR RESPONSE TO LIPID 42 457 4.89e-06 0.0001331
172 REGULATION OF HOMEOSTATIC PROCESS 41 447 6.64e-06 0.0001776
173 MULTICELLULAR ORGANISMAL SIGNALING 18 123 6.595e-06 0.0001776
174 CARDIAC SEPTUM MORPHOGENESIS 11 49 6.613e-06 0.0001776
175 REGULATION OF CELLULAR RESPONSE TO STRESS 56 691 6.742e-06 0.0001793
176 STRIATED MUSCLE CELL DIFFERENTIATION 22 173 6.914e-06 0.0001828
177 REGULATION OF SYNAPSE ASSEMBLY 14 79 7.364e-06 0.0001925
178 CELL FATE COMMITMENT 26 227 7.356e-06 0.0001925
179 POSITIVE REGULATION OF KINASE ACTIVITY 43 482 7.99e-06 0.0002054
180 POSITIVE REGULATION OF CATALYTIC ACTIVITY 102 1518 7.949e-06 0.0002054
181 TELENCEPHALON DEVELOPMENT 26 228 7.966e-06 0.0002054
182 REGULATION OF ADHERENS JUNCTION ORGANIZATION 11 50 8.146e-06 0.0002083
183 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 26 229 8.621e-06 0.0002192
184 CELL CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 24 204 1.039e-05 0.0002627
185 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 29 274 1.056e-05 0.0002641
186 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 31 303 1.053e-05 0.0002641
187 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 20 153 1.183e-05 0.0002943
188 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 20 154 1.305e-05 0.0003212
189 AMEBOIDAL TYPE CELL MIGRATION 20 154 1.305e-05 0.0003212
190 REGULATION OF CHEMOTAXIS 22 180 1.312e-05 0.0003212
191 REGULATION OF HEART CONTRACTION 25 221 1.361e-05 0.0003314
192 CONNECTIVE TISSUE DEVELOPMENT 23 194 1.391e-05 0.0003371
193 LOCOMOTORY BEHAVIOR 22 181 1.433e-05 0.0003455
194 REGULATION OF AXONOGENESIS 21 168 1.451e-05 0.0003479
195 REGULATION OF MAPK CASCADE 53 660 1.534e-05 0.0003647
196 EPITHELIAL CELL DIFFERENTIATION 43 495 1.536e-05 0.0003647
197 COGNITION 27 251 1.574e-05 0.0003717
198 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 61 799 1.667e-05 0.0003918
199 NEUROMUSCULAR JUNCTION DEVELOPMENT 9 36 1.81e-05 0.000421
200 SEMAPHORIN PLEXIN SIGNALING PATHWAY 9 36 1.81e-05 0.000421
201 MUSCLE SYSTEM PROCESS 29 282 1.826e-05 0.0004226
202 REGULATION OF TRANSPORTER ACTIVITY 23 198 1.94e-05 0.0004469
203 GLAND MORPHOGENESIS 15 97 1.952e-05 0.0004474
204 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 18 133 1.982e-05 0.0004521
205 REGULATION OF CELL GROWTH 36 391 2.207e-05 0.0005009
206 CELLULAR RESPONSE TO HORMONE STIMULUS 46 552 2.246e-05 0.0005073
207 REGULATION OF ANATOMICAL STRUCTURE SIZE 41 472 2.415e-05 0.0005428
208 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 46 554 2.457e-05 0.0005497
209 SKELETAL SYSTEM MORPHOGENESIS 23 201 2.473e-05 0.0005506
210 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 16 111 2.57e-05 0.0005695
211 ACTOMYOSIN STRUCTURE ORGANIZATION 13 77 2.664e-05 0.0005875
212 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 45 541 2.878e-05 0.000626
213 REGULATION OF OSTEOBLAST DIFFERENTIATION 16 112 2.879e-05 0.000626
214 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 45 541 2.878e-05 0.000626
215 REGULATION OF ION TRANSPORT 48 592 3.02e-05 0.0006536
216 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 22 190 3.071e-05 0.0006615
217 NEGATIVE REGULATION OF GENE EXPRESSION 98 1493 3.094e-05 0.0006634
218 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 27 262 3.383e-05 0.000722
219 REGULATION OF CELL JUNCTION ASSEMBLY 12 68 3.426e-05 0.0007278
220 RESPONSE TO DRUG 38 431 3.441e-05 0.0007278
221 NEGATIVE REGULATION OF LOCOMOTION 27 263 3.617e-05 0.0007615
222 RESPONSE TO STEROID HORMONE 42 497 3.669e-05 0.0007691
223 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 23 207 3.951e-05 0.0008243
224 REGULATION OF MUSCLE TISSUE DEVELOPMENT 15 103 4.037e-05 0.0008274
225 TRANSCRIPTION INITIATION FROM RNA POLYMERASE II PROMOTER 19 153 4.01e-05 0.0008274
226 CARDIAC MUSCLE TISSUE DEVELOPMENT 18 140 3.991e-05 0.0008274
227 REGULATION OF MUSCLE ORGAN DEVELOPMENT 15 103 4.037e-05 0.0008274
228 EYE DEVELOPMENT 31 326 4.392e-05 0.0008964
229 NEGATIVE REGULATION OF CELL ADHESION 24 223 4.549e-05 0.0009202
230 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 15 104 4.53e-05 0.0009202
231 EAR DEVELOPMENT 22 195 4.578e-05 0.0009221
232 METANEPHROS DEVELOPMENT 13 81 4.633e-05 0.0009292
233 NEGATIVE REGULATION OF PHOSPHORYLATION 37 422 4.89e-05 0.0009723
234 EMBRYONIC ORGAN DEVELOPMENT 36 406 4.881e-05 0.0009723
235 ACTIN FILAMENT BASED MOVEMENT 14 93 4.982e-05 0.0009865
236 RESPIRATORY SYSTEM DEVELOPMENT 22 197 5.346e-05 0.001054
237 RESPONSE TO BMP 14 94 5.622e-05 0.001099
238 CELLULAR RESPONSE TO BMP STIMULUS 14 94 5.622e-05 0.001099
239 REGULATION OF TRANSMEMBRANE TRANSPORT 37 426 5.962e-05 0.001161
240 NEGATIVE REGULATION OF CHEMOTAXIS 10 51 6.036e-05 0.00117
241 PEPTIDYL TYROSINE MODIFICATION 21 186 6.688e-05 0.001291
242 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 11 62 6.87e-05 0.001321
243 REGULATION OF ORGAN GROWTH 12 73 7.081e-05 0.001356
244 CARDIOCYTE DIFFERENTIATION 14 96 7.121e-05 0.001358
245 CARTILAGE DEVELOPMENT 18 147 7.636e-05 0.00145
246 PALATE DEVELOPMENT 13 85 7.764e-05 0.001468
247 REGULATION OF CYTOPLASMIC TRANSPORT 40 481 7.936e-05 0.001495
248 REGENERATION 19 161 8.084e-05 0.001505
249 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 48 616 8.074e-05 0.001505
250 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 48 616 8.074e-05 0.001505
251 ACTIN MEDIATED CELL CONTRACTION 12 74 8.12e-05 0.001505
252 DIGESTIVE SYSTEM DEVELOPMENT 18 148 8.346e-05 0.001535
253 POSITIVE REGULATION OF CELL GROWTH 18 148 8.346e-05 0.001535
254 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 10 53 8.511e-05 0.00154
255 HEART VALVE DEVELOPMENT 8 34 8.49e-05 0.00154
256 CAMP METABOLIC PROCESS 8 34 8.49e-05 0.00154
257 CELL GROWTH 17 135 8.434e-05 0.00154
258 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 24 232 8.539e-05 0.00154
259 MUSCLE CONTRACTION 24 233 9.135e-05 0.001641
260 CELL PROLIFERATION 51 672 9.496e-05 0.001699
261 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 21 191 9.815e-05 0.00175
262 AGING 26 264 0.0001001 0.00177
263 ACTIVATION OF PROTEIN KINASE ACTIVITY 27 279 9.971e-05 0.00177
264 POSITIVE REGULATION OF CELL DEATH 47 605 0.0001027 0.001809
265 NEGATIVE REGULATION OF AXONOGENESIS 11 65 0.0001074 0.001885
266 RESPONSE TO OXYGEN LEVELS 29 311 0.0001082 0.001893
267 REGULATION OF CELLULAR LOCALIZATION 84 1277 0.0001096 0.00191
268 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 17 138 0.0001111 0.001929
269 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 65 926 0.0001123 0.001943
270 CELL CELL ADHESION 47 608 0.0001154 0.001988
271 OVULATION CYCLE 15 113 0.0001193 0.002047
272 SPROUTING ANGIOGENESIS 9 45 0.0001197 0.002047
273 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 19 166 0.000122 0.002079
274 NEGATIVE REGULATION OF AXON GUIDANCE 7 27 0.0001224 0.002079
275 POST EMBRYONIC DEVELOPMENT 13 89 0.0001258 0.002129
276 REGULATION OF BINDING 27 283 0.0001265 0.002133
277 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 62 876 0.0001286 0.002152
278 HOMOPHILIC CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 18 153 0.0001284 0.002152
279 REGULATION OF SENSORY PERCEPTION 8 36 0.0001309 0.002176
280 REGULATION OF SENSORY PERCEPTION OF PAIN 8 36 0.0001309 0.002176
281 REGULATION OF ENDOTHELIAL CELL MIGRATION 15 114 0.000132 0.002185
282 EPITHELIAL TO MESENCHYMAL TRANSITION 10 56 0.0001381 0.00227
283 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 10 56 0.0001381 0.00227
284 GLAND DEVELOPMENT 34 395 0.0001392 0.002281
285 MESONEPHROS DEVELOPMENT 13 90 0.0001413 0.002306
286 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 96 1517 0.0001452 0.002357
287 POSITIVE REGULATION OF CELL CYCLE 30 332 0.0001454 0.002357
288 SEMAPHORIN PLEXIN SIGNALING PATHWAY INVOLVED IN NEURON PROJECTION GUIDANCE 5 13 0.0001512 0.002443
289 CARBOHYDRATE DERIVATIVE METABOLIC PROCESS 71 1047 0.0001555 0.002503
290 MELANOCYTE DIFFERENTIATION 6 20 0.0001566 0.002512
291 CYCLIC NUCLEOTIDE METABOLIC PROCESS 10 57 0.000161 0.002565
292 REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 10 57 0.000161 0.002565
293 TUBE FORMATION 16 129 0.0001616 0.002566
294 RESPONSE TO ACID CHEMICAL 29 319 0.000168 0.002659
295 REGULATION OF GTPASE ACTIVITY 50 673 0.0001854 0.002925
296 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 17 144 0.0001876 0.002949
297 REGULATION OF CELLULAR COMPONENT SIZE 30 337 0.0001889 0.002959
298 HOMEOSTATIC PROCESS 86 1337 0.0001922 0.003001
299 COLLAGEN FIBRIL ORGANIZATION 8 38 0.0001959 0.003008
300 NEGATIVE REGULATION OF AXON EXTENSION 8 38 0.0001959 0.003008
301 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 15 118 0.0001949 0.003008
302 REGULATION OF CELL SIZE 19 172 0.0001948 0.003008
303 POSITIVE REGULATION OF ORGAN GROWTH 8 38 0.0001959 0.003008
304 CARDIAC MUSCLE CELL CONTRACTION 7 29 0.0001993 0.003041
305 NEUROBLAST PROLIFERATION 7 29 0.0001993 0.003041
306 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 22 216 0.0002073 0.003152
307 CARDIAC VENTRICLE DEVELOPMENT 14 106 0.0002102 0.003186
308 SYMPATHETIC NERVOUS SYSTEM DEVELOPMENT 6 21 0.0002112 0.00319
309 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 36 437 0.0002135 0.003194
310 NEURAL PRECURSOR CELL PROLIFERATION 11 70 0.0002128 0.003194
311 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 34 404 0.0002131 0.003194
312 VASCULOGENESIS 10 59 0.0002164 0.003228
313 REGULATION OF CELL CYCLE 65 949 0.0002239 0.003328
314 INSULIN LIKE GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 5 14 0.0002267 0.003339
315 MEMBRANE DEPOLARIZATION DURING CARDIAC MUSCLE CELL ACTION POTENTIAL 5 14 0.0002267 0.003339
316 POSITIVE REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 5 14 0.0002267 0.003339
317 RESPONSE TO RETINOIC ACID 14 107 0.0002323 0.00341
318 REGULATION OF VASCULATURE DEVELOPMENT 23 233 0.0002383 0.003487
319 CELLULAR RESPONSE TO ACID CHEMICAL 19 175 0.0002438 0.003544
320 EMBRYONIC ORGAN MORPHOGENESIS 26 279 0.0002432 0.003544
321 POSITIVE REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 7 30 0.0002502 0.003583
322 STEM CELL PROLIFERATION 10 60 0.0002497 0.003583
323 NEGATIVE REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 7 30 0.0002502 0.003583
324 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 10 60 0.0002497 0.003583
325 CELLULAR RESPONSE TO VASCULAR ENDOTHELIAL GROWTH FACTOR STIMULUS 7 30 0.0002502 0.003583
326 REGIONALIZATION 28 311 0.0002536 0.003619
327 REPRODUCTIVE SYSTEM DEVELOPMENT 34 408 0.000256 0.003642
328 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 15 121 0.0002577 0.003655
329 POSITIVE REGULATION OF CELL ADHESION 32 376 0.000265 0.003736
330 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 18 162 0.0002643 0.003736
331 ADULT BEHAVIOR 16 135 0.0002742 0.003855
332 REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 9 50 0.0002783 0.003885
333 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 9 50 0.0002783 0.003885
334 REGULATION OF RESPONSE TO STRESS 92 1468 0.0002797 0.003885
335 SOMATIC STEM CELL DIVISION 6 22 0.0002797 0.003885
336 DEVELOPMENTAL PIGMENTATION 8 40 0.0002851 0.003938
337 PROTEIN COMPLEX SUBUNIT ORGANIZATION 95 1527 0.0002852 0.003938
338 NEGATIVE REGULATION OF GROWTH 23 236 0.000287 0.00395
339 REPRODUCTION 83 1297 0.0002932 0.004024
340 FOREBRAIN CELL MIGRATION 10 62 0.0003291 0.004491
341 CARDIAC VENTRICLE MORPHOGENESIS 10 62 0.0003291 0.004491
342 LEUKOCYTE ACTIVATION 34 414 0.0003347 0.004547
343 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 13 98 0.0003352 0.004547
344 SENSORY ORGAN MORPHOGENESIS 23 239 0.0003441 0.004654
345 NEGATIVE REGULATION OF MOLECULAR FUNCTION 71 1079 0.0003721 0.005019
346 REGULATION OF CARTILAGE DEVELOPMENT 10 63 0.0003762 0.005044
347 NEUROEPITHELIAL CELL DIFFERENTIATION 10 63 0.0003762 0.005044
348 SALIVARY GLAND DEVELOPMENT 7 32 0.0003834 0.005097
349 ENDOCARDIAL CUSHION DEVELOPMENT 7 32 0.0003834 0.005097
350 REGULATION OF CENTROSOME DUPLICATION 7 32 0.0003834 0.005097
351 RESPONSE TO ABIOTIC STIMULUS 68 1024 0.0003846 0.005099
352 PALLIUM DEVELOPMENT 17 153 0.0003873 0.005119
353 REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 11 75 0.0003952 0.005209
354 NEGATIVE REGULATION OF CELL PROLIFERATION 47 643 0.0004114 0.005408
355 POSITIVE REGULATION OF MAPK CASCADE 37 470 0.0004235 0.005551
356 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 9 53 0.0004379 0.005708
357 NEGATIVE REGULATION OF ION TRANSPORT 15 127 0.000437 0.005708
358 MULTI MULTICELLULAR ORGANISM PROCESS 21 213 0.000444 0.00577
359 NEGATIVE REGULATION OF STEM CELL DIFFERENTIATION 8 43 0.0004788 0.006155
360 NEGATIVE REGULATION OF CELL GROWTH 18 170 0.0004766 0.006155
361 CEREBRAL CORTEX CELL MIGRATION 8 43 0.0004788 0.006155
362 MUSCLE CELL DEVELOPMENT 15 128 0.0004754 0.006155
363 REGULATION OF BEHAVIOR 10 65 0.000487 0.006192
364 BONE DEVELOPMENT 17 156 0.0004859 0.006192
365 CELLULAR RESPONSE TO RETINOIC ACID 10 65 0.000487 0.006192
366 REGULATION OF DNA METABOLIC PROCESS 29 340 0.0004866 0.006192
367 POSITIVE REGULATION OF DNA METABOLIC PROCESS 19 185 0.0004931 0.006235
368 NEPHRON DEVELOPMENT 14 115 0.0004928 0.006235
369 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 13 102 0.0004971 0.006268
370 TRANSMISSION OF NERVE IMPULSE 9 54 0.0005054 0.006356
371 REGULATION OF METAL ION TRANSPORT 28 325 0.0005157 0.006468
372 NEGATIVE REGULATION OF TRANSPORT 36 458 0.0005181 0.006481
373 POSITIVE REGULATION OF CELL CYCLE PROCESS 23 247 0.000548 0.006836
374 REGULATION OF MULTICELLULAR ORGANISM GROWTH 10 66 0.0005519 0.006866
375 RENAL TUBULE DEVELOPMENT 11 78 0.0005573 0.006915
376 DNA TEMPLATED TRANSCRIPTION INITIATION 20 202 0.0005695 0.007048
377 IN UTERO EMBRYONIC DEVELOPMENT 27 311 0.0005724 0.007065
378 REGULATION OF TRANSFORMING GROWTH FACTOR BETA PRODUCTION 6 25 0.0005934 0.007304
379 REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION 20 203 0.0006065 0.007446
380 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 10 67 0.0006237 0.007638
381 RESPONSE TO EXTERNAL STIMULUS 108 1821 0.0006314 0.007691
382 RESPONSE TO ALCOHOL 30 362 0.0006311 0.007691
383 MESODERM DEVELOPMENT 14 118 0.0006404 0.00778
384 REGULATION OF PROTEIN LOCALIZATION 63 950 0.0006485 0.007858
385 CEREBRAL CORTEX DEVELOPMENT 13 105 0.0006582 0.007934
386 REGULATION OF RESPONSE TO WOUNDING 33 413 0.0006571 0.007934
387 SEX DIFFERENTIATION 24 266 0.0006599 0.007934
388 REGULATION OF LIPID METABOLIC PROCESS 25 282 0.0006659 0.007974
389 RHYTHMIC PROCESS 26 298 0.0006667 0.007974
390 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 36 465 0.0006836 0.008135
391 RESPONSE TO MONOAMINE 7 35 0.0006834 0.008135
392 ORGAN GROWTH 10 68 0.0007031 0.008325
393 REGULATION OF NEUROLOGICAL SYSTEM PROCESS 10 68 0.0007031 0.008325
394 NEPHRON EPITHELIUM DEVELOPMENT 12 93 0.0007227 0.008534
395 REGULATION OF MACROPHAGE ACTIVATION 6 26 0.0007431 0.008754
396 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 15 134 0.0007722 0.009074
397 REGULATION OF NEURON APOPTOTIC PROCESS 19 192 0.0007784 0.009123
398 NEURAL TUBE FORMATION 12 94 0.0007961 0.009308
399 CORTICAL CYTOSKELETON ORGANIZATION 7 36 0.0008167 0.009524
400 REGULATION OF CATION TRANSMEMBRANE TRANSPORT 20 208 0.0008241 0.009586
401 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 36 470 0.0008288 0.009617
402 POSITIVE REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 5 18 0.0008387 0.00966
403 POLYOL CATABOLIC PROCESS 5 18 0.0008387 0.00966
404 PHARYNGEAL SYSTEM DEVELOPMENT 5 18 0.0008387 0.00966
405 REGULATION OF MAP KINASE ACTIVITY 27 319 0.0008419 0.009673
406 CARDIAC CONDUCTION 11 82 0.0008565 0.009816
NumGOOverlapSizeP ValueAdj. P Value
1 GROWTH FACTOR BINDING 23 123 3.197e-09 2.97e-06
2 PROTEIN KINASE ACTIVITY 60 640 2.243e-08 1.042e-05
3 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 17 81 6.112e-08 1.893e-05
4 CYTOSKELETAL PROTEIN BINDING 69 819 1.339e-07 2.871e-05
5 ENZYME BINDING 121 1737 1.545e-07 2.871e-05
6 KINASE ACTIVITY 69 842 3.766e-07 5.831e-05
7 PROTEIN COMPLEX BINDING 74 935 5.39e-07 7.154e-05
8 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 35 328 1.101e-06 0.0001278
9 CYTOKINE BINDING 16 92 2.156e-06 0.0001989
10 RECEPTOR BINDING 102 1476 2.355e-06 0.0001989
11 MACROMOLECULAR COMPLEX BINDING 98 1399 2.115e-06 0.0001989
12 MOLECULAR FUNCTION REGULATOR 95 1353 2.783e-06 0.0002155
13 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 13 64 3.218e-06 0.00023
14 ACTIN BINDING 38 393 4.254e-06 0.0002823
15 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 74 992 4.747e-06 0.000294
16 PROTEIN TYROSINE KINASE ACTIVITY 22 176 9.141e-06 0.0005307
17 INTEGRIN BINDING 16 105 1.26e-05 0.0006884
18 CHEMOREPELLENT ACTIVITY 8 27 1.362e-05 0.0007031
19 REGULATORY REGION NUCLEIC ACID BINDING 62 818 1.77e-05 0.0008656
20 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 25 226 1.999e-05 0.0009286
21 ZINC ION BINDING 80 1155 2.882e-05 0.001217
22 PROTEIN DOMAIN SPECIFIC BINDING 50 624 2.82e-05 0.001217
23 DOUBLE STRANDED DNA BINDING 58 764 3.158e-05 0.001276
24 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 50 629 3.468e-05 0.001324
25 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 82 1199 3.564e-05 0.001324
26 TRANSFORMING GROWTH FACTOR BETA BINDING 6 16 3.76e-05 0.001343
27 CELL ADHESION MOLECULE BINDING 21 186 6.688e-05 0.002301
28 MICROTUBULE BINDING 22 201 7.236e-05 0.002401
29 SULFUR COMPOUND BINDING 24 234 9.768e-05 0.003129
30 EXTRACELLULAR MATRIX STRUCTURAL CONSTITUENT 12 76 0.000106 0.003282
31 VOLTAGE GATED SODIUM CHANNEL ACTIVITY 6 20 0.0001566 0.004693
32 TUBULIN BINDING 26 273 0.0001723 0.005001
33 HEPARIN BINDING 18 157 0.0001784 0.005022
34 SEQUENCE SPECIFIC DNA BINDING 70 1037 0.0001977 0.005249
35 RECEPTOR SIGNALING PROTEIN ACTIVITY 19 172 0.0001948 0.005249
36 KINASE BINDING 46 606 0.0002058 0.00531
37 VOLTAGE GATED ION CHANNEL ACTIVITY 20 190 0.0002564 0.006437
38 ENZYME REGULATOR ACTIVITY 65 959 0.0002983 0.007021
39 PROTEIN SERINE THREONINE KINASE ACTIVITY 36 445 0.0003023 0.007021
40 CATION CHANNEL ACTIVITY 27 298 0.0002933 0.007021
41 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 28 315 0.0003125 0.00708
42 PROTEIN DIMERIZATION ACTIVITY 75 1149 0.0003238 0.007162
NumGOOverlapSizeP ValueAdj. P Value
1 NEURON PROJECTION 86 942 6.555e-11 2.052e-08
2 CELL PROJECTION 136 1786 7.026e-11 2.052e-08
3 NEURON PART 99 1265 9.815e-09 1.496e-06
4 POSTSYNAPSE 43 378 1.025e-08 1.496e-06
5 SYNAPSE 67 754 2.745e-08 3.206e-06
6 SYNAPSE PART 55 610 3.135e-07 3.051e-05
7 PROTEINACEOUS EXTRACELLULAR MATRIX 38 356 3.811e-07 3.18e-05
8 SOMATODENDRITIC COMPARTMENT 57 650 4.749e-07 3.467e-05
9 EXTRACELLULAR MATRIX 42 426 8.069e-07 5.236e-05
10 CELL JUNCTION 85 1151 1.352e-06 7.896e-05
11 EXCITATORY SYNAPSE 25 197 1.735e-06 9.211e-05
12 CYTOSKELETON 128 1967 2.519e-06 0.0001226
13 AXON 39 418 7.455e-06 0.000311
14 RECEPTOR COMPLEX 33 327 7.38e-06 0.000311
15 CELL PROJECTION PART 70 946 1.133e-05 0.0004411
16 VOLTAGE GATED SODIUM CHANNEL COMPLEX 6 14 1.52e-05 0.0005549
17 NEURON SPINE 17 121 2.043e-05 0.0007018
18 EXTRACELLULAR MATRIX COMPONENT 17 125 3.138e-05 0.001018
19 SODIUM CHANNEL COMPLEX 6 17 5.596e-05 0.00172
20 SITE OF POLARIZED GROWTH 18 149 9.113e-05 0.002534
21 DENDRITE 38 451 9.051e-05 0.002534
22 INTRACELLULAR VESICLE 83 1259 0.000112 0.002974
23 CELL BODY 40 494 0.0001403 0.003563
24 CELL SURFACE 55 757 0.0001592 0.003832
25 MEMBRANE MICRODOMAIN 27 288 0.0001689 0.003832
26 CYTOPLASMIC VESICLE PART 46 601 0.0001706 0.003832
27 ENDOPLASMIC RETICULUM LUMEN 21 201 0.0002017 0.004362
28 FILOPODIUM 13 94 0.0002206 0.0046
29 ACTIN CYTOSKELETON 36 444 0.0002896 0.005833
30 ACTOMYOSIN 10 62 0.0003291 0.006407
31 CELL CELL JUNCTION 32 383 0.0003669 0.006439
32 SARCOLEMMA 15 125 0.000368 0.006439
33 ACTIN BASED CELL PROJECTION 19 181 0.0003749 0.006439
34 PLASMA MEMBRANE RAFT 12 86 0.0003505 0.006439

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04510_Focal_adhesion 27 200 1.926e-07 3.467e-05
2 hsa04151_PI3K_AKT_signaling_pathway 37 351 7.359e-07 6.623e-05
3 hsa04014_Ras_signaling_pathway 25 236 4.146e-05 0.002488
4 hsa04512_ECM.receptor_interaction 13 85 7.764e-05 0.003494
5 hsa04010_MAPK_signaling_pathway 26 268 0.0001279 0.004604
6 hsa04360_Axon_guidance 16 130 0.0001769 0.005308
7 hsa04810_Regulation_of_actin_cytoskeleton 21 214 0.0004725 0.01215
8 hsa04390_Hippo_signaling_pathway 16 154 0.001177 0.02649
9 hsa04144_Endocytosis 19 203 0.00151 0.0302
10 hsa04020_Calcium_signaling_pathway 17 177 0.001986 0.03574
11 hsa04514_Cell_adhesion_molecules_.CAMs. 14 136 0.002538 0.04153
12 hsa04340_Hedgehog_signaling_pathway 8 56 0.002847 0.04271
13 hsa04350_TGF.beta_signaling_pathway 10 85 0.003894 0.05392
14 hsa04310_Wnt_signaling_pathway 14 151 0.006486 0.08339
15 hsa00230_Purine_metabolism 14 162 0.01172 0.1338
16 hsa04270_Vascular_smooth_muscle_contraction 11 116 0.01268 0.1338
17 hsa04916_Melanogenesis 10 101 0.01286 0.1338
18 hsa04914_Progesterone.mediated_oocyte_maturation 9 87 0.01364 0.1338
19 hsa04520_Adherens_junction 8 73 0.01412 0.1338
20 hsa04970_Salivary_secretion 9 89 0.01566 0.1409
21 hsa04540_Gap_junction 9 90 0.01675 0.1436
22 hsa04910_Insulin_signaling_pathway 12 138 0.01794 0.1467
23 hsa03022_Basal_transcription_factors 5 37 0.02155 0.1686
24 hsa04730_Long.term_depression 7 70 0.03284 0.2463
25 hsa00562_Inositol_phosphate_metabolism 6 57 0.03751 0.2701
26 hsa00670_One_carbon_pool_by_folate 3 18 0.04158 0.2878
27 hsa00531_Glycosaminoglycan_degradation 3 19 0.04782 0.3188
28 hsa04114_Oocyte_meiosis 9 114 0.06203 0.3951
29 hsa04974_Protein_digestion_and_absorption 7 81 0.06365 0.3951
30 hsa00051_Fructose_and_mannose_metabolism 4 36 0.07066 0.4239
31 hsa04912_GnRH_signaling_pathway 8 101 0.07461 0.4245
32 hsa04710_Circadian_rhythm_._mammal 3 23 0.07695 0.4245
33 hsa04630_Jak.STAT_signaling_pathway 11 155 0.07782 0.4245
34 hsa04115_p53_signaling_pathway 6 69 0.08058 0.4266
35 hsa04722_Neurotrophin_signaling_pathway 9 127 0.1045 0.5373
36 hsa04260_Cardiac_muscle_contraction 6 77 0.1201 0.5798
37 hsa04666_Fc_gamma_R.mediated_phagocytosis 7 95 0.1219 0.5798
38 hsa04062_Chemokine_signaling_pathway 12 189 0.1256 0.5798
39 hsa04070_Phosphatidylinositol_signaling_system 6 78 0.1256 0.5798
40 hsa00512_Mucin_type_O.Glycan_biosynthesis 3 30 0.1416 0.6374
41 hsa04972_Pancreatic_secretion 7 101 0.1531 0.6721
42 hsa04012_ErbB_signaling_pathway 6 87 0.1803 0.7727
43 hsa04720_Long.term_potentiation 5 70 0.1908 0.7744
44 hsa04150_mTOR_signaling_pathway 4 52 0.1915 0.7744
45 hsa04210_Apoptosis 6 89 0.1936 0.7744
46 hsa04976_Bile_secretion 5 71 0.1984 0.7765
47 hsa04971_Gastric_acid_secretion 5 74 0.222 0.8503
48 hsa04370_VEGF_signaling_pathway 5 76 0.2382 0.8932
49 hsa04145_Phagosome 9 156 0.2434 0.8941
50 hsa04664_Fc_epsilon_RI_signaling_pathway 5 79 0.263 0.9468
51 hsa00760_Nicotinate_and_nicotinamide_metabolism 2 24 0.2825 0.988
52 hsa04320_Dorso.ventral_axis_formation 2 25 0.2989 0.988
53 hsa00280_Valine._leucine_and_isoleucine_degradation 3 44 0.3019 0.988
54 hsa02010_ABC_transporters 3 44 0.3019 0.988
55 hsa04973_Carbohydrate_digestion_and_absorption 3 44 0.3019 0.988
56 hsa00534_Glycosaminoglycan_biosynthesis_._heparan_sulfate 2 26 0.3153 0.9984
57 hsa00010_Glycolysis_._Gluconeogenesis 4 65 0.3162 0.9984
58 hsa04975_Fat_digestion_and_absorption 3 46 0.3261 1
59 hsa04660_T_cell_receptor_signaling_pathway 6 108 0.3337 1
60 hsa04920_Adipocytokine_signaling_pathway 4 68 0.3462 1
61 hsa00510_N.Glycan_biosynthesis 3 49 0.3624 1
62 hsa04530_Tight_junction 7 133 0.3627 1
63 hsa00020_Citrate_cycle_.TCA_cycle. 2 30 0.3796 1
64 hsa00640_Propanoate_metabolism 2 32 0.4108 1
65 hsa04662_B_cell_receptor_signaling_pathway 4 75 0.4161 1
66 hsa04142_Lysosome 6 121 0.4356 1
67 hsa00564_Glycerophospholipid_metabolism 4 80 0.4651 1
68 hsa00565_Ether_lipid_metabolism 2 36 0.4707 1
69 hsa03030_DNA_replication 2 36 0.4707 1
70 hsa04110_Cell_cycle 6 128 0.4896 1
71 hsa04380_Osteoclast_differentiation 6 128 0.4896 1
72 hsa03015_mRNA_surveillance_pathway 4 83 0.4938 1
73 hsa00600_Sphingolipid_metabolism 2 40 0.5268 1
74 hsa04640_Hematopoietic_cell_lineage 4 88 0.54 1
75 hsa04960_Aldosterone.regulated_sodium_reabsorption 2 42 0.5533 1
76 hsa00310_Lysine_degradation 2 44 0.5788 1
77 hsa04962_Vasopressin.regulated_water_reabsorption 2 44 0.5788 1
78 hsa04670_Leukocyte_transendothelial_migration 5 117 0.5839 1
79 hsa03420_Nucleotide_excision_repair 2 45 0.5911 1
80 hsa00514_Other_types_of_O.glycan_biosynthesis 2 46 0.6031 1
81 hsa04141_Protein_processing_in_endoplasmic_reticulum 7 168 0.6049 1
82 hsa00980_Metabolism_of_xenobiotics_by_cytochrome_P450 3 71 0.6052 1
83 hsa03018_RNA_degradation 3 71 0.6052 1
84 hsa04330_Notch_signaling_pathway 2 47 0.6149 1
85 hsa00520_Amino_sugar_and_nucleotide_sugar_metabolism 2 48 0.6264 1
86 hsa00240_Pyrimidine_metabolism 4 99 0.6334 1
87 hsa00480_Glutathione_metabolism 2 50 0.6486 1
88 hsa00500_Starch_and_sucrose_metabolism 2 54 0.6899 1
89 hsa04120_Ubiquitin_mediated_proteolysis 5 139 0.7317 1
90 hsa04621_NOD.like_receptor_signaling_pathway 2 59 0.7357 1
91 hsa04610_Complement_and_coagulation_cascades 2 69 0.8102 1
92 hsa03320_PPAR_signaling_pathway 2 70 0.8166 1
93 hsa04620_Toll.like_receptor_signaling_pathway 3 102 0.8286 1
94 hsa00982_Drug_metabolism_._cytochrome_P450 2 73 0.8344 1
95 hsa04146_Peroxisome 2 79 0.8654 1
96 hsa03013_RNA_transport 4 152 0.9036 1
97 hsa04650_Natural_killer_cell_mediated_cytotoxicity 2 136 0.9837 1
98 hsa04740_Olfactory_transduction 3 388 1 1

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation

Quest ID: 4bb96bfe55d5bad199c4a3cfa78c02c0