CR2Cancer

Summary
Symbol	BRDT
Name	bromodomain testis associated
Aliases	BRD6; CT9; cancer/testis antigen 9; Bromodomain testis-specific protein
Location	1p22.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Domain, Function and Classification > Gene Ontology > KEGG and Reactome Pathway

> Domain, Function and Classification

[ TOP ]

Domain

PF17035 Bromodomain extra-terminal - transcription regulation
PF17105 C-terminal domain of bromodomain protein 4
PF00439 Bromodomain

Function

Testis-specific chromatin protein that specifically binds histone H4 acetylated at 'Lys-5' and 'Lys-8' (H4K5ac and H4K8ac, respectively) and plays a key role in spermatogenesis. Required in late pachytene spermatocytes: plays a role in meiotic and post-meiotic cells by binding to acetylated histones at the promoter of specific meiotic and post-meiotic genes, facilitating their activation at the appropriate time. In the post-meiotic phase of spermatogenesis, binds to hyperacetylated histones and participates in their general removal from DNA. Also acts as a component of the splicing machinery in pachytene spermatocytes and round spermatids and participates in 3'-UTR truncation of specific mRNAs in post-meiotic spermatids. Required for chromocenter organization, a structure comprised of peri-centromeric heterochromatin.

Classification

Class	Modification	Substrate	Product	PubMed
Histone modification read	#	H4K5ac, H4K8ac	#	22901802

> Gene Ontology [ TOP ]
Biological Process	GO:0001207 histone displacement GO:0006338 chromatin remodeling GO:0006397 mRNA processing GO:0007126 meiotic nuclear division GO:0007127 meiosis I GO:0007140 male meiosis GO:0007141 male meiosis I GO:0007283 spermatogenesis GO:0008380 RNA splicing GO:0034728 nucleosome organization GO:0043484 regulation of RNA splicing GO:0048232 male gamete generation GO:0051037 regulation of transcription involved in meiotic cell cycle GO:0051039 positive regulation of transcription involved in meiotic cell cycle GO:0051321 meiotic cell cycle GO:0071824 protein-DNA complex subunit organization GO:1903046 meiotic cell cycle process
Molecular Function	GO:0003713 transcription coactivator activity GO:0042393 histone binding GO:0070577 lysine-acetylated histone binding
Cellular Component	-

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	-

Summary
Symbol	BRDT
Name	bromodomain testis associated
Aliases	BRD6; CT9; cancer/testis antigen 9; Bromodomain testis-specific protein
Location	1p22.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Mutation landscape in primary tumor tissue from TCGA > Mutation landscape in cancer cell line from CCLE > All mutations from COSMIC database V81 > Variations from text mining

> The Cancer Genome Atlas (TCGA) [ TOP ]

> Cancer Cell Line Encyclopedia (CCLE) [ TOP ]

> Catalogue of Somatic Mutations in Cancer (COSMIC)

[ TOP ]

COSMIC ID	CDS change	AA change	Mutation Type	Anatomical Site
COSM465087	c.2530G>T	p.E844*	Substitution - Nonsense	Kidney
COSM913251	c.2819C>T	p.T940I	Substitution - Missense	Endometrium
COSM5003134	c.2504A>G	p.E835G	Substitution - Missense	Pancreas
COSM5643331	c.327delC	p.N109fs*14	Deletion - Frameshift	Oesophagus
COSM682727	c.234A>T	p.T78T	Substitution - coding silent	Lung
COSM256417	c.244C>T	p.R82C	Substitution - Missense	Large_intestine
COSM5688363	c.1579G>T	p.G527*	Substitution - Nonsense	Soft_tissue
COSM309525	c.1280A>G	p.Q427R	Substitution - Missense	Soft_tissue
COSM159413	c.1353G>T	p.K451N	Substitution - Missense	Breast
COSM1688028	c.979G>A	p.D327N	Substitution - Missense	Biliary_tract
COSM913227	c.574G>T	p.V192L	Substitution - Missense	Endometrium
COSM536715	c.858G>T	p.K286N	Substitution - Missense	Stomach
COSM2259829	c.245G>A	p.R82H	Substitution - Missense	Large_intestine
COSM5716884	c.1311C>T	p.L437L	Substitution - coding silent	Skin
COSM1688033	c.1904C>T	p.S635F	Substitution - Missense	Skin
COSM4924164	c.171T>C	p.D57D	Substitution - coding silent	Liver
COSM913241	c.1715C>T	p.S572L	Substitution - Missense	Skin
COSM4564713	c.1371_1372GG>AA	p.E458K	Substitution - Missense	Skin
COSM20511	c.266C>T	p.A89V	Substitution - Missense	Stomach
COSM389808	c.17G>A	p.R6Q	Substitution - Missense	Lung
COSM3952731	c.1377G>T	p.K459N	Substitution - Missense	Ovary
COSM1246226	c.2753A>C	p.Q918P	Substitution - Missense	Oesophagus
COSM4457482	c.1035C>T	p.F345F	Substitution - coding silent	Skin
COSM4524523	c.1265G>A	p.R422H	Substitution - Missense	Skin
COSM536715	c.858G>T	p.K286N	Substitution - Missense	Large_intestine
COSM2152322	c.2819C>A	p.T940K	Substitution - Missense	Central_nervous_system
COSM3493325	c.803A>G	p.K268R	Substitution - Missense	Skin
COSM234448	c.2523G>A	p.R841R	Substitution - coding silent	Skin
COSM4010589	c.1014G>A	p.A338A	Substitution - coding silent	Stomach
COSM3361052	c.1131G>A	p.P377P	Substitution - coding silent	Kidney
COSM1126920	c.748C>G	p.P250A	Substitution - Missense	Prostate
COSM1344880	c.1125G>T	p.K375N	Substitution - Missense	Large_intestine
COSM4758806	c.1007A>C	p.K336T	Substitution - Missense	Large_intestine
COSM5969584	c.608C>T	p.T203I	Substitution - Missense	Upper_aerodigestive_tract
COSM2259863	c.2082C>T	p.C694C	Substitution - coding silent	Large_intestine
COSM279204	c.1460+9C>A	p.?	Unknown	Large_intestine
COSM426825	c.1063G>A	p.D355N	Substitution - Missense	Breast
COSM3493339	c.2462C>T	p.S821F	Substitution - Missense	Skin
COSM536715	c.858G>T	p.K286N	Substitution - Missense	Large_intestine
COSM5636505	c.1229A>G	p.N410S	Substitution - Missense	Oesophagus
COSM1344882	c.1499A>C	p.K500T	Substitution - Missense	Large_intestine
COSM5880130	c.1411C>T	p.P471S	Substitution - Missense	Skin
COSM1636971	c.2316A>T	p.I772I	Substitution - coding silent	Bone
COSM4998536	c.1655T>C	p.I552T	Substitution - Missense	Pancreas
COSM4417547	c.184C>A	p.Q62K	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM2152322	c.2819C>A	p.T940K	Substitution - Missense	Central_nervous_system
COSM274166	c.1860A>C	p.T620T	Substitution - coding silent	Large_intestine
COSM4666139	c.1325A>T	p.Q442L	Substitution - Missense	Large_intestine
COSM1602786	c.1610T>C	p.I537T	Substitution - Missense	Liver
COSM913226	c.445+1G>A	p.?	Unknown	Endometrium
COSM4973862	c.1233T>A	p.S411S	Substitution - coding silent	Oesophagus
COSM1185515	c.2543A>T	p.K848M	Substitution - Missense	Lung
COSM913233	c.1108G>A	p.E370K	Substitution - Missense	Endometrium
COSM5638775	c.2000C>T	p.S667L	Substitution - Missense	Oesophagus
COSM279205	c.1751-8T>A	p.?	Unknown	Large_intestine
COSM5785250	c.2624C>A	p.S875Y	Substitution - Missense	Breast
COSM3361052	c.1131G>A	p.P377P	Substitution - coding silent	Skin
COSM465085	c.143T>C	p.F48S	Substitution - Missense	Kidney
COSM4902770	c.2389-1G>A	p.?	Unknown	Skin
COSM414736	c.1510G>A	p.E504K	Substitution - Missense	Urinary_tract
COSM3806099	c.1358A>G	p.E453G	Substitution - Missense	Breast
COSM5892528	c.997G>A	p.D333N	Substitution - Missense	Skin
COSM3493328	c.1222G>A	p.E408K	Substitution - Missense	Skin
COSM4404628	c.2671G>A	p.E891K	Substitution - Missense	Skin
COSM5602921	c.1355A>T	p.K452I	Substitution - Missense	Skin
COSM234448	c.2523G>A	p.R841R	Substitution - coding silent	Kidney
COSM1627249	c.2052A>G	p.K684K	Substitution - coding silent	Liver
COSM2259834	c.587C>T	p.S196L	Substitution - Missense	Cervix
COSM4144250	c.714A>C	p.K238N	Substitution - Missense	Thyroid
COSM3396185	c.1112C>T	p.T371M	Substitution - Missense	Prostate
COSM913237	c.1384G>T	p.E462*	Substitution - Nonsense	Endometrium
COSM1240903	c.1392T>C	p.V464V	Substitution - coding silent	Oesophagus
COSM3493329	c.1244C>T	p.S415F	Substitution - Missense	Skin
COSM3396185	c.1112C>T	p.T371M	Substitution - Missense	Prostate
COSM1126918	c.1645C>T	p.P549S	Substitution - Missense	Prostate
COSM913233	c.1108G>A	p.E370K	Substitution - Missense	Stomach
COSM1184921	c.2521C>T	p.R841W	Substitution - Missense	Large_intestine
COSM3493338	c.2172C>T	p.T724T	Substitution - coding silent	Skin
COSM682726	c.555T>C	p.S185S	Substitution - coding silent	Lung
COSM4450974	c.992A>G	p.Y331C	Substitution - Missense	Skin
COSM171492	c.934G>A	p.V312I	Substitution - Missense	Central_nervous_system
COSM3377314	c.2330C>A	p.P777Q	Substitution - Missense	Pancreas
COSM5992312	c.2288-8G>A	p.?	Unknown	Prostate
COSM5716884	c.1311C>T	p.L437L	Substitution - coding silent	Skin
COSM5745673	c.1235C>T	p.S412F	Substitution - Missense	Pancreas
COSM5992312	c.2288-8G>A	p.?	Unknown	Prostate
COSM5629926	c.2464T>C	p.S822P	Substitution - Missense	Oesophagus
COSM913225	c.369G>T	p.E123D	Substitution - Missense	Endometrium
COSM3396185	c.1112C>T	p.T371M	Substitution - Missense	Prostate
COSM4409939	c.2363C>T	p.S788F	Substitution - Missense	Oesophagus
COSM5880130	c.1411C>T	p.P471S	Substitution - Missense	Skin
COSM1492148	c.1691T>A	p.L564Q	Substitution - Missense	Kidney
COSM1688030	c.1129C>T	p.P377S	Substitution - Missense	Skin
COSM4010583	c.79C>T	p.R27*	Substitution - Nonsense	Stomach
COSM4758806	c.1007A>C	p.K336T	Substitution - Missense	Stomach
COSM1688025	c.505G>A	p.E169K	Substitution - Missense	Skin
COSM5892528	c.997G>A	p.D333N	Substitution - Missense	Skin
COSM389808	c.17G>A	p.R6Q	Substitution - Missense	Skin
COSM1602786	c.1610T>C	p.I537T	Substitution - Missense	Liver
COSM5414284	c.331-6T>C	p.?	Unknown	Haematopoietic_and_lymphoid_tissue
COSM4819702	c.611C>T	p.A204V	Substitution - Missense	Cervix
COSM913235	c.1317T>G	p.V439V	Substitution - coding silent	Endometrium
COSM3730061	c.948G>A	p.P316P	Substitution - coding silent	Stomach
COSM913238	c.1448A>C	p.K483T	Substitution - Missense	Endometrium
COSM913248	c.2765G>A	p.R922K	Substitution - Missense	Endometrium
COSM913250	c.2805A>C	p.Q935H	Substitution - Missense	Endometrium
COSM536713	c.1113G>A	p.T371T	Substitution - coding silent	Stomach
COSM4666138	c.199T>C	p.Y67H	Substitution - Missense	Large_intestine
COSM913237	c.1384G>T	p.E462*	Substitution - Nonsense	Endometrium
COSM1667708	c.1696G>T	p.E566*	Substitution - Nonsense	Large_intestine
COSM1727390	c.2226A>T	p.Q742H	Substitution - Missense	Liver
COSM198362	c.2045C>T	p.P682L	Substitution - Missense	Skin
COSM3720985	c.2048C>A	p.S683Y	Substitution - Missense	Upper_aerodigestive_tract
COSM4980932	c.147A>T	p.S49S	Substitution - coding silent	Oesophagus
COSM913224	c.213A>C	p.K71N	Substitution - Missense	Endometrium
COSM913242	c.1774G>T	p.E592*	Substitution - Nonsense	Endometrium
COSM1627247	c.1717G>T	p.A573S	Substitution - Missense	Liver
COSM3493337	c.2033C>T	p.P678L	Substitution - Missense	Skin
COSM3493330	c.1252G>A	p.E418K	Substitution - Missense	Skin
COSM4010584	c.80G>A	p.R27Q	Substitution - Missense	Stomach
COSM1688026	c.544C>T	p.P182S	Substitution - Missense	Skin
COSM913243	c.1774G>C	p.E592Q	Substitution - Missense	Endometrium
COSM1184920	c.2596G>A	p.D866N	Substitution - Missense	Large_intestine
COSM4187910	c.943A>T	p.N315Y	Substitution - Missense	Kidney
COSM290301	c.1107C>T	p.F369F	Substitution - coding silent	Endometrium
COSM4499564	c.533C>T	p.P178L	Substitution - Missense	Skin
COSM4526907	c.1415G>A	p.R472K	Substitution - Missense	Skin
COSM3493333	c.1534T>C	p.Y512H	Substitution - Missense	Skin
COSM373508	c.2467G>A	p.D823N	Substitution - Missense	Lung
COSM234448	c.2523G>A	p.R841R	Substitution - coding silent	Skin
COSM5681472	c.1755G>T	p.K585N	Substitution - Missense	Soft_tissue
COSM913249	c.2791G>A	p.D931N	Substitution - Missense	Endometrium
COSM5798827	c.1821G>A	p.L607L	Substitution - coding silent	Breast
COSM171492	c.934G>A	p.V312I	Substitution - Missense	Large_intestine
COSM4917901	c.346G>T	p.V116F	Substitution - Missense	Liver
COSM12803	c.862C>T	p.H288Y	Substitution - Missense	Lung
COSM1728859	c.330+2T>A	p.?	Unknown	Liver
COSM3790331	c.438C>A	p.I146I	Substitution - coding silent	Urinary_tract
COSM5969583	c.296A>T	p.N99I	Substitution - Missense	Upper_aerodigestive_tract
COSM682724	c.612G>T	p.A204A	Substitution - coding silent	Lung
COSM5681471	c.1249G>C	p.D417H	Substitution - Missense	Soft_tissue
COSM913230	c.844G>T	p.E282*	Substitution - Nonsense	Endometrium
COSM3493326	c.965T>A	p.I322N	Substitution - Missense	Skin
COSM5015874	c.935delT	p.V313fs*31	Deletion - Frameshift	Kidney
COSM4010586	c.389T>C	p.L130S	Substitution - Missense	Stomach
COSM4010590	c.2403G>A	p.K801K	Substitution - coding silent	Stomach
COSM4772606	c.1264C>T	p.R422C	Substitution - Missense	Stomach
COSM1184919	c.456G>T	p.Q152H	Substitution - Missense	Large_intestine
COSM1246227	c.879G>A	p.W293*	Substitution - Nonsense	Oesophagus
COSM1667706	c.1309C>T	p.L437F	Substitution - Missense	Large_intestine
COSM20511	c.266C>T	p.A89V	Substitution - Missense	Stomach
COSM4666143	c.2489G>T	p.R830I	Substitution - Missense	Large_intestine
COSM3790333	c.2200C>T	p.H734Y	Substitution - Missense	Urinary_tract
COSM3369871	c.286G>C	p.E96Q	Substitution - Missense	Thyroid
COSM913229	c.736A>C	p.K246Q	Substitution - Missense	Endometrium
COSM4529383	c.1595G>A	p.R532Q	Substitution - Missense	Skin
COSM3493334	c.1558C>T	p.L520L	Substitution - coding silent	Skin
COSM913236	c.1358A>C	p.E453A	Substitution - Missense	Endometrium
COSM4570453	c.2730T>C	p.R910R	Substitution - coding silent	Skin
COSM4564513	c.1225_1226GG>AA	p.G409K	Substitution - Missense	Skin
COSM256417	c.244C>T	p.R82C	Substitution - Missense	Large_intestine
COSM682725	c.574G>C	p.V192L	Substitution - Missense	Lung
COSM913228	c.613G>A	p.A205T	Substitution - Missense	Endometrium
COSM1320842	c.1119T>G	p.F373L	Substitution - Missense	Ovary
COSM3419570	c.858G>A	p.K286K	Substitution - coding silent	Large_intestine
COSM3396185	c.1112C>T	p.T371M	Substitution - Missense	Prostate
COSM1283679	c.1145A>G	p.E382G	Substitution - Missense	Autonomic_ganglia
COSM290301	c.1107C>T	p.F369F	Substitution - coding silent	Large_intestine
COSM3493335	c.1779A>G	p.E593E	Substitution - coding silent	Skin
COSM3493328	c.1222G>A	p.E408K	Substitution - Missense	Skin
COSM5675045	c.330G>T	p.K110N	Substitution - Missense	Soft_tissue
COSM1667707	c.1594C>T	p.R532*	Substitution - Nonsense	Haematopoietic_and_lymphoid_tissue
COSM913246	c.2352G>A	p.T784T	Substitution - coding silent	Stomach
COSM913223	c.19C>T	p.Q7*	Substitution - Nonsense	Endometrium
COSM1688033	c.1904C>T	p.S635F	Substitution - Missense	Skin
COSM414735	c.1820T>G	p.L607R	Substitution - Missense	Urinary_tract
COSM1688031	c.1646C>T	p.P549L	Substitution - Missense	Skin
COSM4570452	c.2730T>A	p.R910R	Substitution - coding silent	Skin
COSM5716884	c.1311C>T	p.L437L	Substitution - coding silent	Skin
COSM1688027	c.563C>T	p.P188L	Substitution - Missense	Skin
COSM279203	c.1852C>T	p.R618C	Substitution - Missense	Large_intestine
COSM1688026	c.544C>T	p.P182S	Substitution - Missense	Skin
COSM3493332	c.1476G>A	p.R492R	Substitution - coding silent	Skin
COSM465086	c.2513T>C	p.V838A	Substitution - Missense	Kidney
COSM5381693	c.2540G>A	p.R847Q	Substitution - Missense	Skin
COSM221405	c.2480A>C	p.N827T	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM1688029	c.1057C>T	p.P353S	Substitution - Missense	Skin
COSM1688034	c.2227G>A	p.E743K	Substitution - Missense	Skin
COSM5777308	c.1556G>T	p.S519I	Substitution - Missense	Breast
COSM682722	c.961A>G	p.T321A	Substitution - Missense	Lung
COSM4889105	c.116T>C	p.V39A	Substitution - Missense	Upper_aerodigestive_tract
COSM5584571	c.2595G>A	p.R865R	Substitution - coding silent	Skin
COSM913234	c.1295C>T	p.A432V	Substitution - Missense	Endometrium
COSM3790332	c.532C>A	p.P178T	Substitution - Missense	Urinary_tract
COSM5381691	c.97C>T	p.Q33*	Substitution - Nonsense	Skin
COSM3866239	c.94C>A	p.L32I	Substitution - Missense	Skin
COSM913233	c.1108G>A	p.E370K	Substitution - Missense	Skin
COSM3396185	c.1112C>T	p.T371M	Substitution - Missense	Prostate
COSM913241	c.1715C>T	p.S572L	Substitution - Missense	Endometrium
COSM3419569	c.738A>C	p.K246N	Substitution - Missense	Large_intestine
COSM1667706	c.1309C>T	p.L437F	Substitution - Missense	Large_intestine
COSM309526	c.115G>T	p.V39F	Substitution - Missense	Lung
COSM4835028	c.2447C>T	p.S816L	Substitution - Missense	Cervix
COSM3493339	c.2462C>T	p.S821F	Substitution - Missense	Skin
COSM913247	c.2662G>T	p.E888*	Substitution - Nonsense	Endometrium
COSM4931826	c.771T>C	p.S257S	Substitution - coding silent	Liver
COSM5464466	c.1696G>A	p.E566K	Substitution - Missense	Large_intestine
COSM5734878	c.231T>A	p.N77K	Substitution - Missense	Pancreas
COSM913242	c.1774G>T	p.E592*	Substitution - Nonsense	Endometrium
COSM318945	c.1036A>T	p.M346L	Substitution - Missense	Lung
COSM5823462	c.2047T>A	p.S683T	Substitution - Missense	Liver
COSM5433710	c.216C>A	p.N72K	Substitution - Missense	Oesophagus
COSM913232	c.1038G>A	p.M346I	Substitution - Missense	Endometrium
COSM913233	c.1108G>A	p.E370K	Substitution - Missense	Stomach
COSM4666140	c.2024A>G	p.E675G	Substitution - Missense	Large_intestine
COSM1688026	c.544C>T	p.P182S	Substitution - Missense	Skin
COSM5992312	c.2288-8G>A	p.?	Unknown	Prostate
COSM4981241	c.1551G>A	p.Q517Q	Substitution - coding silent	Oesophagus
COSM3493336	c.1847G>A	p.R616K	Substitution - Missense	Skin
COSM73861	c.514T>G	p.F172V	Substitution - Missense	Ovary
COSM5381692	c.1999T>A	p.S667T	Substitution - Missense	Skin
COSM5381694	c.2827G>A	p.E943K	Substitution - Missense	Skin
COSM3866240	c.795G>A	p.K265K	Substitution - coding silent	Skin
COSM913239	c.1526C>A	p.P509H	Substitution - Missense	Endometrium
COSM3493327	c.1134T>A	p.I378I	Substitution - coding silent	Skin
COSM4144250	c.714A>C	p.K238N	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM309525	c.1280A>G	p.Q427R	Substitution - Missense	Lung
COSM5987587	c.1502C>G	p.S501C	Substitution - Missense	Salivary_gland
COSM5679361	c.2584G>T	p.E862*	Substitution - Nonsense	Soft_tissue
COSM4010585	c.338A>T	p.D113V	Substitution - Missense	Stomach
COSM1627248	c.1908A>T	p.R636R	Substitution - coding silent	Liver
COSM3751454	c.1230C>G	p.N410K	Substitution - Missense	Large_intestine
COSM309526	c.115G>T	p.V39F	Substitution - Missense	Soft_tissue
COSM5417365	c.1390G>T	p.V464F	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM426826	c.1193G>A	p.G398D	Substitution - Missense	Breast
COSM5596361	c.39C>T	p.N13N	Substitution - coding silent	Skin
COSM290301	c.1107C>T	p.F369F	Substitution - coding silent	Lung
COSM5917003	c.112G>A	p.V38I	Substitution - Missense	Skin
COSM238984	c.1036A>C	p.M346L	Substitution - Missense	Prostate
COSM426827	c.1625C>G	p.P542R	Substitution - Missense	Breast
COSM5881810	c.418G>T	p.V140L	Substitution - Missense	Skin
COSM354919	c.899A>G	p.D300G	Substitution - Missense	Lung
COSM913231	c.959G>T	p.G320V	Substitution - Missense	Endometrium
COSM913233	c.1108G>A	p.E370K	Substitution - Missense	Oesophagus
COSM5992312	c.2288-8G>A	p.?	Unknown	Prostate
COSM4666141	c.2351C>T	p.T784M	Substitution - Missense	Large_intestine
COSM5139608	c.1459_1460+2delAAGT	p.?	Unknown	Large_intestine
COSM1688028	c.979G>A	p.D327N	Substitution - Missense	Skin
COSM1688024	c.347T>C	p.V116A	Substitution - Missense	Skin
COSM1667708	c.1696G>T	p.E566*	Substitution - Nonsense	Large_intestine
COSM5431104	c.1824T>G	p.D608E	Substitution - Missense	Oesophagus
COSM913244	c.2227G>T	p.E743*	Substitution - Nonsense	Endometrium
COSM913240	c.1543A>G	p.K515E	Substitution - Missense	Endometrium
COSM4666142	c.2403G>T	p.K801N	Substitution - Missense	Large_intestine
COSM171492	c.934G>A	p.V312I	Substitution - Missense	Large_intestine
COSM4524184	c.1246G>A	p.E416K	Substitution - Missense	Skin
COSM4010584	c.80G>A	p.R27Q	Substitution - Missense	Large_intestine
COSM5353025	c.1142T>G	p.V381G	Substitution - Missense	Large_intestine
COSM3806098	c.633G>A	p.V211V	Substitution - coding silent	Breast
COSM98867	c.2705C>T	p.S902F	Substitution - Missense	Stomach
COSM12803	c.862C>T	p.H288Y	Substitution - Missense	Lung
COSM3361051	c.719T>C	p.V240A	Substitution - Missense	Kidney
COSM290301	c.1107C>T	p.F369F	Substitution - coding silent	Large_intestine
COSM400815	c.1047C>A	p.Y349*	Substitution - Nonsense	Lung
COSM345104	c.1736C>A	p.P579Q	Substitution - Missense	Lung
COSM913245	c.2274T>C	p.I758I	Substitution - coding silent	Endometrium
COSM5784352	c.1061C>T	p.P354L	Substitution - Missense	Breast
COSM3493331	c.1372G>A	p.E458K	Substitution - Missense	Skin
COSM5796665	c.1521T>A	p.A507A	Substitution - coding silent	Breast
COSM2259829	c.245G>A	p.R82H	Substitution - Missense	Large_intestine
COSM4895916	c.892C>T	p.P298S	Substitution - Missense	Skin
COSM231852	c.869C>T	p.S290L	Substitution - Missense	Skin
COSM237051	c.1908A>G	p.R636R	Substitution - coding silent	Prostate
COSM1688032	c.1727G>A	p.R576K	Substitution - Missense	Skin
COSM913237	c.1384G>T	p.E462*	Substitution - Nonsense	Large_intestine
COSM1667707	c.1594C>T	p.R532*	Substitution - Nonsense	Pancreas
COSM3396185	c.1112C>T	p.T371M	Substitution - Missense	Central_nervous_system
COSM1688026	c.544C>T	p.P182S	Substitution - Missense	Skin
COSM5794879	c.2489G>C	p.R830T	Substitution - Missense	Breast
COSM4010588	c.835A>G	p.I279V	Substitution - Missense	Stomach
COSM1688026	c.544C>T	p.P182S	Substitution - Missense	Skin
COSM4010587	c.731C>A	p.P244H	Substitution - Missense	Stomach
COSM4572760	c.840T>C	p.L280L	Substitution - coding silent	Skin
COSM913246	c.2352G>A	p.T784T	Substitution - coding silent	Endometrium
COSM5053749	c.2211A>G	p.L737L	Substitution - coding silent	Stomach
COSM4529383	c.1595G>A	p.R532Q	Substitution - Missense	Haematopoietic_and_lymphoid_tissue
COSM5992662	c.2092G>C	p.E698Q	Substitution - Missense	Prostate
COSM913230	c.844G>T	p.E282*	Substitution - Nonsense	Endometrium
COSM3493324	c.526G>A	p.E176K	Substitution - Missense	Skin
COSM4977945	c.1067A>G	p.H356R	Substitution - Missense	Oesophagus
COSM3419568	c.212A>C	p.K71T	Substitution - Missense	Large_intestine
COSM682723	c.866T>C	p.F289S	Substitution - Missense	Lung
COSM4421322	c.403C>A	p.Q135K	Substitution - Missense	Pleura
COSM2259835	c.753G>A	p.K251K	Substitution - coding silent	Large_intestine

> Text Mining based Variations [ TOP ]
There is no record for BRDT.

Summary
Symbol	BRDT
Name	bromodomain testis associated
Aliases	BRD6; CT9; cancer/testis antigen 9; Bromodomain testis-specific protein
Location	1p22.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Post-translational modification (PTM)

> Post-translational modification (PTM)

[ TOP ]

Filter By:

Uniprot ID	Position	Amino Acid	Description	Upstream Enzyme	Affected By Mutation	Amino Acid Sequence Variant

Summary
Symbol	BRDT
Name	bromodomain testis associated
Aliases	BRD6; CT9; cancer/testis antigen 9; Bromodomain testis-specific protein
Location	1p22.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Expression analysis in primary tumor tissue from TCGA > Expression level in cancer cell line from CCLE > Expression level in human normal tissue from HPA > Text mining based expression change

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Differential expression analysis for cancers with more than 10 normal samples

Cancer	Full Name	# N	# T	Median (N)	Median (T)	LogFC	Adj. P	Status
BLCA	Bladder urothelial carcinoma	19	408	-6.035	-6.121	0.106	0.893	NS
BRCA	Breast invasive carcinoma	112	1100	-4.476	-4.666	0.293	0.281	NS
ESCA	Esophageal carcinoma	11	185	-5.407	-6.055	0.418	0.778	NS
HNSC	Head and Neck squamous cell carcinoma	44	522	-6.439	-6.285	1.395	0.00829	Over
LUAD	Lung adenocarcinoma	59	517	-5.509	-3.441	3.015	1.39e-07	Over
LUSC	Lung squamous cell carcinoma	51	501	-6.392	-5.592	2.464	3.07e-05	Over
TGCT	Testicular Germ Cell Tumors	0	156	NA	4.378	NA	NA	NA

> Cancer Cell Line Encyclopedia (CCLE)

[ TOP ]

Tissue	Cell Line	Expression Level (Microarray)
Autonomic ganglia	CHP126	4
Autonomic ganglia	CHP212	3.8
Autonomic ganglia	IMR32	3.8
Autonomic ganglia	KELLY	3.8
Autonomic ganglia	KPNRTBM1	3.8
Autonomic ganglia	KPNSI9S	3.6
Autonomic ganglia	KPNYN	3.6
Autonomic ganglia	MHHNB11	4.1
Autonomic ganglia	NB1	3.9
Autonomic ganglia	NH6	4
Autonomic ganglia	SHSY5Y	3.7
Autonomic ganglia	SIMA	3.8
Autonomic ganglia	SKNAS	4
Autonomic ganglia	SKNBE2	3.9
Autonomic ganglia	SKNDZ	3.6
Autonomic ganglia	SKNFI	4
Autonomic ganglia	SKNSH	3.7
Biliary tract	HUCCT1	3.7
Biliary tract	HUH28	3.8
Biliary tract	SNU1079	3.8
Biliary tract	SNU1196	3.8
Biliary tract	SNU245	3.8
Biliary tract	SNU308	3.6
Biliary tract	SNU478	3.6
Bone	143B	3.8
Bone	A673	4
Bone	CADOES1	3.5
Bone	CAL78	4.1
Bone	G292CLONEA141B1	3.9
Bone	HOS	3.7
Bone	HS706T	3.5
Bone	HS737T	3.4
Bone	HS819T	4
Bone	HS821T	3.7
Bone	HS822T	3.9
Bone	HS863T	3.7
Bone	HS870T	3.9
Bone	HS888T	3.6
Bone	MG63	3.9
Bone	MHHES1	3.9
Bone	OUMS27	3.6
Bone	RDES	3.8
Bone	SJSA1	3.7
Bone	SKES1	4
Bone	SKNMC	3.7
Bone	SW1353	3.6
Bone	T173	4.2
Bone	TC71	3.8
Bone	U2OS	3.6
Breast	AU565	4
Breast	BT20	3.6
Breast	BT474	3.6
Breast	BT483	3.6
Breast	BT549	3.6
Breast	CAL120	3.7
Breast	CAL148	3.6
Breast	CAL51	3.4
Breast	CAL851	3.5
Breast	CAMA1	6.3
Breast	DU4475	3.8
Breast	EFM192A	3.8
Breast	EFM19	3.8
Breast	EVSAT	3.5
Breast	HCC1143	3.7
Breast	HCC1187	3.6
Breast	HCC1395	3.9
Breast	HCC1419	3.5
Breast	HCC1428	4.1
Breast	HCC1500	7.7
Breast	HCC1569	4.5
Breast	HCC1599	3.6
Breast	HCC1806	3.8
Breast	HCC1937	3.5
Breast	HCC1954	3.7
Breast	HCC202	3.9
Breast	HCC2157	4
Breast	HCC2218	4.5
Breast	HCC38	3.7
Breast	HCC70	3.7
Breast	HDQP1	3.7
Breast	HMC18	4.1
Breast	HS274T	3.5
Breast	HS281T	3.6
Breast	HS343T	3.7
Breast	HS578T	4
Breast	HS606T	3.8
Breast	HS739T	3.7
Breast	HS742T	3.9
Breast	JIMT1	4.3
Breast	KPL1	4
Breast	MCF7	3.7
Breast	MDAMB134VI	4
Breast	MDAMB157	3.7
Breast	MDAMB175VII	4
Breast	MDAMB231	3.5
Breast	MDAMB361	3.6
Breast	MDAMB415	4
Breast	MDAMB436	3.8
Breast	MDAMB453	4.3
Breast	MDAMB468	3.5
Breast	SKBR3	3.4
Breast	T47D	3.6
Breast	UACC812	3.6
Breast	UACC893	4
Breast	YMB1	4
Breast	ZR751	3.8
Breast	ZR7530	3.9
Central nervous system	1321N1	3.6
Central nervous system	42MGBA	4.3
Central nervous system	8MGBA	3.5
Central nervous system	A172	3.7
Central nervous system	AM38	3.6
Central nervous system	BECKER	3.8
Central nervous system	CAS1	3.9
Central nervous system	CCFSTTG1	3.7
Central nervous system	D283MED	7.7
Central nervous system	D341MED	3.5
Central nervous system	DAOY	3.8
Central nervous system	DBTRG05MG	4
Central nervous system	DKMG	3.9
Central nervous system	GAMG	3.6
Central nervous system	GB1	3.9
Central nervous system	GI1	4
Central nervous system	GMS10	4.2
Central nervous system	GOS3	3.8
Central nervous system	H4	3.7
Central nervous system	HS683	3.8
Central nervous system	KALS1	3.8
Central nervous system	KG1C	3.6
Central nervous system	KNS42	3.9
Central nervous system	KNS60	3.8
Central nervous system	KNS81	3.5
Central nervous system	KS1	4.1
Central nervous system	LN18	3.7
Central nervous system	LN229	3.9
Central nervous system	M059K	3.8
Central nervous system	MOGGCCM	3.6
Central nervous system	MOGGUVW	3.8
Central nervous system	NMCG1	3.6
Central nervous system	ONS76	4.1
Central nervous system	SF126	3.8
Central nervous system	SF295	3.6
Central nervous system	SNB19	3.7
Central nervous system	SNU1105	3.9
Central nervous system	SNU201	3.8
Central nervous system	SNU466	4.3
Central nervous system	SNU489	3.7
Central nervous system	SNU626	3.9
Central nervous system	SNU738	4
Central nervous system	SW1088	3.4
Central nervous system	SW1783	3.7
Central nervous system	T98G	3.8
Central nervous system	TM31	3.7
Central nervous system	U118MG	3.8
Central nervous system	U138MG	3.9
Central nervous system	U251MG	3.6
Central nervous system	U87MG	3.7
Central nervous system	YH13	3.5
Central nervous system	YKG1	4
Endometrium	AN3CA	4
Endometrium	COLO684	3.9
Endometrium	EFE184	3.4
Endometrium	EN	3.7
Endometrium	ESS1	3.6
Endometrium	HEC108	3.7
Endometrium	HEC151	3.8
Endometrium	HEC1A	3.8
Endometrium	HEC1B	3.5
Endometrium	HEC251	4
Endometrium	HEC265	3.7
Endometrium	HEC50B	3.9
Endometrium	HEC59	4.1
Endometrium	HEC6	3.6
Endometrium	ISHIKAWAHERAKLIO02ER	3.7
Endometrium	JHUEM1	3.9
Endometrium	JHUEM2	3.8
Endometrium	JHUEM3	3.8
Endometrium	KLE	3.7
Endometrium	MFE280	4
Endometrium	MFE296	3.9
Endometrium	MFE319	3.9
Endometrium	RL952	3.7
Endometrium	SNGM	3.8
Endometrium	SNU1077	3.6
Endometrium	SNU685	3.9
Endometrium	TEN	4
Haematopoietic and lymphoid	697	3.7
Haematopoietic and lymphoid	A3KAW	9.7
Haematopoietic and lymphoid	A4FUK	3.8
Haematopoietic and lymphoid	ALLSIL	3.7
Haematopoietic and lymphoid	AML193	3.5
Haematopoietic and lymphoid	AMO1	4.1
Haematopoietic and lymphoid	BCP1	9.3
Haematopoietic and lymphoid	BDCM	3.5
Haematopoietic and lymphoid	BL41	4.1
Haematopoietic and lymphoid	BL70	4.2
Haematopoietic and lymphoid	BV173	3.6
Haematopoietic and lymphoid	CA46	3.9
Haematopoietic and lymphoid	CI1	4
Haematopoietic and lymphoid	CMK115	3.7
Haematopoietic and lymphoid	CMK86	4
Haematopoietic and lymphoid	CMK	3.9
Haematopoietic and lymphoid	CMLT1	4.1
Haematopoietic and lymphoid	COLO775	3.9
Haematopoietic and lymphoid	DAUDI	4
Haematopoietic and lymphoid	DB	4.1
Haematopoietic and lymphoid	DEL	3.6
Haematopoietic and lymphoid	DND41	3.9
Haematopoietic and lymphoid	DOHH2	3.6
Haematopoietic and lymphoid	EB1	3.9
Haematopoietic and lymphoid	EB2	3.7
Haematopoietic and lymphoid	EHEB	4
Haematopoietic and lymphoid	EJM	3.9
Haematopoietic and lymphoid	EM2	3.5
Haematopoietic and lymphoid	EOL1	3.8
Haematopoietic and lymphoid	F36P	4
Haematopoietic and lymphoid	GA10	4.2
Haematopoietic and lymphoid	GDM1	3.6
Haematopoietic and lymphoid	GRANTA519	3.9
Haematopoietic and lymphoid	HDLM2	3.8
Haematopoietic and lymphoid	HDMYZ	4.2
Haematopoietic and lymphoid	HEL9217	3.6
Haematopoietic and lymphoid	HEL	4.2
Haematopoietic and lymphoid	HH	3.9
Haematopoietic and lymphoid	HL60	3.7
Haematopoietic and lymphoid	HPBALL	3.8
Haematopoietic and lymphoid	HS604T	3.8
Haematopoietic and lymphoid	HS611T	3.5
Haematopoietic and lymphoid	HS616T	3.5
Haematopoietic and lymphoid	HS751T	4
Haematopoietic and lymphoid	HT	4
Haematopoietic and lymphoid	HTK	4.1
Haematopoietic and lymphoid	HUNS1	3.8
Haematopoietic and lymphoid	HUT102	3.6
Haematopoietic and lymphoid	HUT78	5.2
Haematopoietic and lymphoid	JEKO1	3.5
Haematopoietic and lymphoid	JK1	3.7
Haematopoietic and lymphoid	JM1	3.8
Haematopoietic and lymphoid	JURKAT	4.2
Haematopoietic and lymphoid	JURLMK1	4
Haematopoietic and lymphoid	JVM2	3.8
Haematopoietic and lymphoid	JVM3	3.7
Haematopoietic and lymphoid	K562	3.6
Haematopoietic and lymphoid	KARPAS299	3.9
Haematopoietic and lymphoid	KARPAS422	4
Haematopoietic and lymphoid	KARPAS620	3.7
Haematopoietic and lymphoid	KASUMI1	4.2
Haematopoietic and lymphoid	KASUMI2	3.6
Haematopoietic and lymphoid	KASUMI6	3.6
Haematopoietic and lymphoid	KCL22	3.6
Haematopoietic and lymphoid	KE37	3.7
Haematopoietic and lymphoid	KE97	3.5
Haematopoietic and lymphoid	KG1	3.5
Haematopoietic and lymphoid	KHM1B	7.1
Haematopoietic and lymphoid	KIJK	3.8
Haematopoietic and lymphoid	KMH2	4
Haematopoietic and lymphoid	KMM1	7
Haematopoietic and lymphoid	KMS11	4.1
Haematopoietic and lymphoid	KMS12BM	3.8
Haematopoietic and lymphoid	KMS18	4
Haematopoietic and lymphoid	KMS20	3.8
Haematopoietic and lymphoid	KMS21BM	3.6
Haematopoietic and lymphoid	KMS26	3.7
Haematopoietic and lymphoid	KMS27	3.7
Haematopoietic and lymphoid	KMS28BM	4.5
Haematopoietic and lymphoid	KMS34	3.7
Haematopoietic and lymphoid	KO52	4.3
Haematopoietic and lymphoid	KOPN8	4
Haematopoietic and lymphoid	KU812	3.7
Haematopoietic and lymphoid	KYO1	3.9
Haematopoietic and lymphoid	L1236	3.8
Haematopoietic and lymphoid	L363	3.7
Haematopoietic and lymphoid	L428	3.9
Haematopoietic and lymphoid	L540	3.8
Haematopoietic and lymphoid	LAMA84	3.7
Haematopoietic and lymphoid	LOUCY	3.8
Haematopoietic and lymphoid	LP1	3.9
Haematopoietic and lymphoid	M07E	3.7
Haematopoietic and lymphoid	MC116	3.9
Haematopoietic and lymphoid	ME1	3.8
Haematopoietic and lymphoid	MEC1	4
Haematopoietic and lymphoid	MEC2	4
Haematopoietic and lymphoid	MEG01	3.9
Haematopoietic and lymphoid	MHHCALL2	3.5
Haematopoietic and lymphoid	MHHCALL3	4
Haematopoietic and lymphoid	MHHCALL4	4
Haematopoietic and lymphoid	MINO	3.6
Haematopoietic and lymphoid	MJ	4.2
Haematopoietic and lymphoid	MM1S	3.8
Haematopoietic and lymphoid	MOLM13	3.7
Haematopoietic and lymphoid	MOLM16	4.1
Haematopoietic and lymphoid	MOLM6	3.8
Haematopoietic and lymphoid	MOLP2	3.8
Haematopoietic and lymphoid	MOLP8	4.1
Haematopoietic and lymphoid	MOLT13	4
Haematopoietic and lymphoid	MOLT16	3.7
Haematopoietic and lymphoid	MOLT4	3.5
Haematopoietic and lymphoid	MONOMAC1	3.5
Haematopoietic and lymphoid	MONOMAC6	3.6
Haematopoietic and lymphoid	MOTN1	3.7
Haematopoietic and lymphoid	MUTZ5	3.8
Haematopoietic and lymphoid	MV411	3.8
Haematopoietic and lymphoid	NALM19	3.6
Haematopoietic and lymphoid	NALM1	3.9
Haematopoietic and lymphoid	NALM6	3.7
Haematopoietic and lymphoid	NAMALWA	4
Haematopoietic and lymphoid	NB4	3.6
Haematopoietic and lymphoid	NCIH929	3.8
Haematopoietic and lymphoid	NCO2	4.2
Haematopoietic and lymphoid	NOMO1	3.6
Haematopoietic and lymphoid	NUDHL1	3.6
Haematopoietic and lymphoid	NUDUL1	4.2
Haematopoietic and lymphoid	OCIAML2	4.2
Haematopoietic and lymphoid	OCIAML3	3.5
Haematopoietic and lymphoid	OCIAML5	3.8
Haematopoietic and lymphoid	OCILY10	4
Haematopoietic and lymphoid	OCILY19	4
Haematopoietic and lymphoid	OCILY3	4
Haematopoietic and lymphoid	OCIM1	3.7
Haematopoietic and lymphoid	OPM2	4
Haematopoietic and lymphoid	P12ICHIKAWA	4
Haematopoietic and lymphoid	P31FUJ	4
Haematopoietic and lymphoid	P3HR1	3.7
Haematopoietic and lymphoid	PCM6	3.9
Haematopoietic and lymphoid	PEER	3.9
Haematopoietic and lymphoid	PF382	3.6
Haematopoietic and lymphoid	PFEIFFER	3.7
Haematopoietic and lymphoid	PL21	4
Haematopoietic and lymphoid	RAJI	4
Haematopoietic and lymphoid	RCHACV	4
Haematopoietic and lymphoid	REC1	3.9
Haematopoietic and lymphoid	REH	5
Haematopoietic and lymphoid	RI1	3.6
Haematopoietic and lymphoid	RL	4.1
Haematopoietic and lymphoid	RPMI8226	3.8
Haematopoietic and lymphoid	RPMI8402	3.7
Haematopoietic and lymphoid	RS411	3.6
Haematopoietic and lymphoid	SEM	3.9
Haematopoietic and lymphoid	SET2	3.7
Haematopoietic and lymphoid	SIGM5	3.6
Haematopoietic and lymphoid	SKM1	3.8
Haematopoietic and lymphoid	SKMM2	4.5
Haematopoietic and lymphoid	SR786	3.8
Haematopoietic and lymphoid	ST486	4.3
Haematopoietic and lymphoid	SUDHL10	3.8
Haematopoietic and lymphoid	SUDHL1	3.6
Haematopoietic and lymphoid	SUDHL4	3.9
Haematopoietic and lymphoid	SUDHL5	3.6
Haematopoietic and lymphoid	SUDHL6	3.8
Haematopoietic and lymphoid	SUDHL8	4.4
Haematopoietic and lymphoid	SUPB15	3.6
Haematopoietic and lymphoid	SUPHD1	4.1
Haematopoietic and lymphoid	SUPM2	4.1
Haematopoietic and lymphoid	SUPT11	3.7
Haematopoietic and lymphoid	SUPT1	3.9
Haematopoietic and lymphoid	TALL1	3.8
Haematopoietic and lymphoid	TF1	4
Haematopoietic and lymphoid	THP1	3.6
Haematopoietic and lymphoid	TO175T	3.8
Haematopoietic and lymphoid	TOLEDO	3.5
Haematopoietic and lymphoid	U266B1	3.6
Haematopoietic and lymphoid	U937	4
Haematopoietic and lymphoid	UT7	4
Haematopoietic and lymphoid	WSUDLCL2	4.1
Kidney	769P	4.1
Kidney	786O	3.6
Kidney	A498	3.5
Kidney	A704	3.7
Kidney	ACHN	3.5
Kidney	BFTC909	3.8
Kidney	CAKI1	3.8
Kidney	CAKI2	3.5
Kidney	CAL54	3.5
Kidney	KMRC1	3.8
Kidney	KMRC20	3.8
Kidney	KMRC2	3.7
Kidney	KMRC3	4.4
Kidney	OSRC2	3.8
Kidney	RCC10RGB	3.7
Kidney	SNU1272	3.6
Kidney	SNU349	4.5
Kidney	TUHR10TKB	4.2
Kidney	TUHR14TKB	4
Kidney	TUHR4TKB	3.8
Kidney	VMRCRCW	3.9
Kidney	VMRCRCZ	4.2
Large intestine	C2BBE1	4
Large intestine	CCK81	3.7
Large intestine	CL11	3.4
Large intestine	CL14	3.7
Large intestine	CL34	3.8
Large intestine	CL40	3.7
Large intestine	COLO205	4.2
Large intestine	COLO320	3.8
Large intestine	COLO678	3.7
Large intestine	CW2	4
Large intestine	DLD1	3.9
Large intestine	GP2D	3.9
Large intestine	HCC56	3.9
Large intestine	HCT116	3.7
Large intestine	HCT15	3.6
Large intestine	HS675T	3.7
Large intestine	HS698T	3.7
Large intestine	HT115	3.7
Large intestine	HT29	3.9
Large intestine	HT55	3.9
Large intestine	KM12	3.5
Large intestine	LOVO	3.6
Large intestine	LS1034	3.8
Large intestine	LS123	3.8
Large intestine	LS180	3.6
Large intestine	LS411N	3.7
Large intestine	LS513	4
Large intestine	MDST8	4.2
Large intestine	NCIH508	3.5
Large intestine	NCIH716	4
Large intestine	NCIH747	3.8
Large intestine	OUMS23	3.5
Large intestine	RCM1	4.1
Large intestine	RKO	4.1
Large intestine	SKCO1	3.9
Large intestine	SNU1040	3.8
Large intestine	SNU1197	3.8
Large intestine	SNU175	3.8
Large intestine	SNU283	3.9
Large intestine	SNU407	3.6
Large intestine	SNU503	3.6
Large intestine	SNU61	3.7
Large intestine	SNU81	3.9
Large intestine	SNUC1	4.2
Large intestine	SNUC2A	3.7
Large intestine	SNUC4	3.6
Large intestine	SNUC5	3.9
Large intestine	SW1116	4
Large intestine	SW1417	3.6
Large intestine	SW1463	3.8
Large intestine	SW403	3.5
Large intestine	SW480	3.9
Large intestine	SW48	3.7
Large intestine	SW620	3.4
Large intestine	SW837	4
Large intestine	SW948	3.6
Large intestine	T84	3.6
Liver	ALEXANDERCELLS	4
Liver	C3A	3.9
Liver	HEP3B217	3.8
Liver	HEPG2	3.4
Liver	HLE	4.2
Liver	HLF	3.7
Liver	HUH1	4
Liver	HUH6	4.2
Liver	HUH7	8.6
Liver	JHH1	3.9
Liver	JHH2	3.7
Liver	JHH4	3.5
Liver	JHH5	3.5
Liver	JHH6	3.9
Liver	JHH7	3.9
Liver	LI7	3.9
Liver	PLCPRF5	3.8
Liver	SKHEP1	3.8
Liver	SNU182	3.6
Liver	SNU387	3.9
Liver	SNU398	3.9
Liver	SNU423	4.1
Liver	SNU449	3.8
Liver	SNU475	3.8
Liver	SNU761	3.5
Liver	SNU878	3.9
Liver	SNU886	4
Lung	A549	3.6
Lung	ABC1	3.8
Lung	BEN	3.5
Lung	CAL12T	3.8
Lung	CALU1	3.6
Lung	CALU3	3.5
Lung	CALU6	3.8
Lung	CHAGOK1	4
Lung	COLO668	3.7
Lung	COLO699	3.7
Lung	CORL105	3.9
Lung	CORL23	3.6
Lung	CORL24	4
Lung	CORL279	3.8
Lung	CORL311	3.8
Lung	CORL47	3.8
Lung	CORL51	4.1
Lung	CORL88	3.7
Lung	CORL95	3.8
Lung	CPCN	3.8
Lung	DMS114	4
Lung	DMS153	3.5
Lung	DMS273	3.5
Lung	DMS454	7
Lung	DMS53	4.1
Lung	DMS79	3.3
Lung	DV90	3.6
Lung	EBC1	3.8
Lung	EPLC272H	4.2
Lung	HARA	8.7
Lung	HCC1171	3.5
Lung	HCC1195	8.8
Lung	HCC15	4
Lung	HCC2279	3.7
Lung	HCC2935	3.8
Lung	HCC33	3.8
Lung	HCC366	4
Lung	HCC4006	3.8
Lung	HCC44	3.9
Lung	HCC78	3.7
Lung	HCC827	7.4
Lung	HCC95	4
Lung	HLC1	3.9
Lung	HLFA	3.7
Lung	HS229T	4.1
Lung	HS618T	3.8
Lung	IALM	3.7
Lung	KNS62	4
Lung	LC1F	3.8
Lung	LC1SQSF	4.1
Lung	LCLC103H	3.8
Lung	LCLC97TM1	3.5
Lung	LK2	3.6
Lung	LOUNH91	4
Lung	LU65	3.9
Lung	LU99	3.8
Lung	LUDLU1	3.5
Lung	LXF289	3.7
Lung	MORCPR	3.5
Lung	NCIH1048	3.6
Lung	NCIH1092	3.8
Lung	NCIH1105	3.8
Lung	NCIH1155	3.8
Lung	NCIH1184	3.7
Lung	NCIH1299	3.8
Lung	NCIH1339	3.8
Lung	NCIH1341	3.6
Lung	NCIH1355	3.7
Lung	NCIH1373	3.9
Lung	NCIH1385	9.3
Lung	NCIH1395	4
Lung	NCIH1435	4.6
Lung	NCIH1436	3.9
Lung	NCIH1437	3.9
Lung	NCIH146	3.7
Lung	NCIH1563	4
Lung	NCIH1568	3.7
Lung	NCIH1573	4.1
Lung	NCIH1581	3.7
Lung	NCIH1618	3.6
Lung	NCIH1623	3.7
Lung	NCIH1648	3.7
Lung	NCIH1650	4.4
Lung	NCIH1651	3.7
Lung	NCIH1666	3.5
Lung	NCIH1693	3.8
Lung	NCIH1694	3.7
Lung	NCIH1703	3.8
Lung	NCIH1734	7.8
Lung	NCIH1755	5.8
Lung	NCIH1781	3.7
Lung	NCIH1792	3.8
Lung	NCIH1793	3.6
Lung	NCIH1836	3.7
Lung	NCIH1838	8.5
Lung	NCIH1869	3.6
Lung	NCIH1876	3.8
Lung	NCIH1915	5.7
Lung	NCIH1930	3.6
Lung	NCIH1944	3.8
Lung	NCIH1963	3.6
Lung	NCIH196	3.8
Lung	NCIH1975	4
Lung	NCIH2009	7.9
Lung	NCIH2023	3.8
Lung	NCIH2029	4
Lung	NCIH2030	4
Lung	NCIH2066	3.6
Lung	NCIH2081	3.7
Lung	NCIH2085	4
Lung	NCIH2087	8
Lung	NCIH209	3.6
Lung	NCIH2106	3.6
Lung	NCIH2110	4
Lung	NCIH211	3.6
Lung	NCIH2122	3.5
Lung	NCIH2126	3.5
Lung	NCIH2141	3.7
Lung	NCIH2170	3.6
Lung	NCIH2171	3.9
Lung	NCIH2172	3.8
Lung	NCIH2196	3.9
Lung	NCIH2227	3.8
Lung	NCIH2228	3.7
Lung	NCIH226	3.7
Lung	NCIH2286	4
Lung	NCIH2291	4
Lung	NCIH2342	3.7
Lung	NCIH2347	4.3
Lung	NCIH23	4.1
Lung	NCIH2405	3.6
Lung	NCIH2444	3.7
Lung	NCIH292	3.6
Lung	NCIH322	4.3
Lung	NCIH3255	3.7
Lung	NCIH358	4
Lung	NCIH441	3.4
Lung	NCIH446	3.6
Lung	NCIH460	3.6
Lung	NCIH510	9.1
Lung	NCIH520	3.6
Lung	NCIH522	3.9
Lung	NCIH524	3.4
Lung	NCIH526	3.9
Lung	NCIH596	3.8
Lung	NCIH647	7.3
Lung	NCIH650	6.7
Lung	NCIH661	8.7
Lung	NCIH69	3.9
Lung	NCIH727	3.6
Lung	NCIH810	3.5
Lung	NCIH82	3.6
Lung	NCIH838	3.6
Lung	NCIH841	3.5
Lung	NCIH854	3.8
Lung	NCIH889	3.8
Lung	PC14	3.9
Lung	RERFLCAD1	3.7
Lung	RERFLCAD2	3.6
Lung	RERFLCAI	3.6
Lung	RERFLCKJ	3.5
Lung	RERFLCMS	3.5
Lung	RERFLCSQ1	4.1
Lung	SBC5	4.3
Lung	SCLC21H	3.7
Lung	SHP77	3.9
Lung	SKLU1	4
Lung	SKMES1	3.7
Lung	SQ1	6.8
Lung	SW1271	3.5
Lung	SW1573	3.9
Lung	SW900	3.7
Lung	VMRCLCD	3.9
Lung	VMRCLCP	3.8
Oesophagus	COLO680N	3.8
Oesophagus	ECGI10	3.7
Oesophagus	KYSE140	9
Oesophagus	KYSE150	3.5
Oesophagus	KYSE180	9.1
Oesophagus	KYSE270	6.3
Oesophagus	KYSE30	3.8
Oesophagus	KYSE410	3.5
Oesophagus	KYSE450	4.9
Oesophagus	KYSE510	3.8
Oesophagus	KYSE520	4.3
Oesophagus	KYSE70	3.6
Oesophagus	OE19	3.8
Oesophagus	OE33	3.8
Oesophagus	TE10	3.9
Oesophagus	TE11	3.8
Oesophagus	TE14	3.7
Oesophagus	TE15	3.5
Oesophagus	TE1	3.9
Oesophagus	TE4	3.5
Oesophagus	TE5	3.6
Oesophagus	TE6	9.9
Oesophagus	TE8	3.4
Oesophagus	TE9	3.8
Oesophagus	TT	3.7
Ovary	59M	4.5
Ovary	A2780	3.8
Ovary	CAOV3	3.6
Ovary	CAOV4	3.5
Ovary	COLO704	3.7
Ovary	COV318	3.8
Ovary	COV362	3.9
Ovary	COV434	4.4
Ovary	COV504	3.6
Ovary	COV644	3.9
Ovary	EFO21	3.9
Ovary	EFO27	3.5
Ovary	ES2	3.9
Ovary	FUOV1	3.5
Ovary	HEYA8	4.5
Ovary	HS571T	4.1
Ovary	IGROV1	3.8
Ovary	JHOC5	3.8
Ovary	JHOM1	3.8
Ovary	JHOM2B	3.8
Ovary	JHOS2	3.7
Ovary	JHOS4	3.8
Ovary	KURAMOCHI	3.8
Ovary	MCAS	3.9
Ovary	NIHOVCAR3	3.6
Ovary	OAW28	4
Ovary	OAW42	4.3
Ovary	OC314	3.5
Ovary	OC316	3.5
Ovary	ONCODG1	3.6
Ovary	OV56	4.2
Ovary	OV7	4
Ovary	OV90	3.9
Ovary	OVCAR4	3.7
Ovary	OVCAR8	3.9
Ovary	OVISE	3.8
Ovary	OVK18	3.8
Ovary	OVKATE	3.6
Ovary	OVMANA	3.8
Ovary	OVSAHO	3.2
Ovary	OVTOKO	3.7
Ovary	RMGI	3.6
Ovary	RMUGS	3.6
Ovary	SKOV3	3.6
Ovary	SNU119	3.6
Ovary	SNU840	4
Ovary	SNU8	4.4
Ovary	TOV112D	3.6
Ovary	TOV21G	3.6
Ovary	TYKNU	3.9
Pancreas	ASPC1	3.5
Pancreas	BXPC3	4.2
Pancreas	CAPAN1	3.8
Pancreas	CAPAN2	3.7
Pancreas	CFPAC1	3.7
Pancreas	DANG	3.6
Pancreas	HPAC	4
Pancreas	HPAFII	3.5
Pancreas	HS766T	3.6
Pancreas	HUPT3	3.7
Pancreas	HUPT4	3.7
Pancreas	KCIMOH1	3.6
Pancreas	KLM1	3.6
Pancreas	KP2	3.7
Pancreas	KP3	3.9
Pancreas	KP4	3.4
Pancreas	L33	3.6
Pancreas	MIAPACA2	4
Pancreas	PANC0203	3.9
Pancreas	PANC0213	3.7
Pancreas	PANC0327	3.8
Pancreas	PANC0403	3.8
Pancreas	PANC0504	3.5
Pancreas	PANC0813	3.5
Pancreas	PANC1005	3.7
Pancreas	PANC1	3.8
Pancreas	PATU8902	3.9
Pancreas	PATU8988S	3.6
Pancreas	PATU8988T	4.1
Pancreas	PK1	3.6
Pancreas	PK45H	4
Pancreas	PK59	3.5
Pancreas	PL45	4.2
Pancreas	PSN1	3.6
Pancreas	QGP1	3.6
Pancreas	SNU213	3.7
Pancreas	SNU324	3.8
Pancreas	SNU410	3.7
Pancreas	SU8686	3.9
Pancreas	SUIT2	4.2
Pancreas	SW1990	3.8
Pancreas	T3M4	3.7
Pancreas	TCCPAN2	3.6
Pancreas	YAPC	3.6
Pleura	ACCMESO1	4
Pleura	DM3	3.7
Pleura	ISTMES1	4.1
Pleura	ISTMES2	3.7
Pleura	JL1	3.7
Pleura	MPP89	4
Pleura	MSTO211H	3.7
Pleura	NCIH2052	3.8
Pleura	NCIH2452	3.8
Pleura	NCIH28	3.8
Prostate	22RV1	3.6
Prostate	DU145	7.5
Prostate	LNCAPCLONEFGC	3.9
Prostate	MDAPCA2B	5.2
Prostate	NCIH660	3.5
Prostate	PC3	3.7
Prostate	VCAP	4.2
Salivary gland	A253	3.8
Salivary gland	YD15	3.8
Skin	A101D	3.7
Skin	A2058	3.8
Skin	A375	3.7
Skin	C32	4
Skin	CHL1	3.6
Skin	CJM	3.5
Skin	COLO679	3.6
Skin	COLO741	3.7
Skin	COLO783	4
Skin	COLO792	4.3
Skin	COLO800	3.7
Skin	COLO818	3.9
Skin	COLO829	3.5
Skin	COLO849	3.5
Skin	G361	4
Skin	GRM	3.8
Skin	HMCB	3.4
Skin	HS294T	3.5
Skin	HS600T	3.5
Skin	HS688AT	3.8
Skin	HS695T	3.9
Skin	HS839T	3.7
Skin	HS852T	3.6
Skin	HS895T	3.9
Skin	HS934T	3.7
Skin	HS936T	4.1
Skin	HS939T	3.9
Skin	HS940T	3.7
Skin	HS944T	3.7
Skin	HT144	3.8
Skin	IGR1	4.1
Skin	IGR37	3.8
Skin	IGR39	3.7
Skin	IPC298	3.7
Skin	K029AX	3.7
Skin	LOXIMVI	4.2
Skin	MALME3M	3.9
Skin	MDAMB435S	3.6
Skin	MELHO	3.7
Skin	MELJUSO	3.4
Skin	MEWO	3.7
Skin	RPMI7951	4.3
Skin	RVH421	3.7
Skin	SH4	3.5
Skin	SKMEL1	3.7
Skin	SKMEL24	3.4
Skin	SKMEL28	3.5
Skin	SKMEL2	3.8
Skin	SKMEL30	3.7
Skin	SKMEL31	3.8
Skin	SKMEL3	3.8
Skin	SKMEL5	3.8
Skin	UACC257	3.9
Skin	UACC62	4
Skin	WM115	3.8
Skin	WM1799	3.7
Skin	WM2664	3.6
Skin	WM793	3.7
Skin	WM88	3.9
Skin	WM983B	4.1
Small intestine	HUTU80	3.9
Soft tissue	A204	3.8
Soft tissue	G401	4.6
Soft tissue	G402	3.7
Soft tissue	GCT	3.6
Soft tissue	HS729	3.8
Soft tissue	HT1080	3.7
Soft tissue	KYM1	4.1
Soft tissue	MESSA	3.7
Soft tissue	RD	3.8
Soft tissue	RH30	4
Soft tissue	RH41	3.5
Soft tissue	RKN	4.2
Soft tissue	S117	3.6
Soft tissue	SJRH30	3.8
Soft tissue	SKLMS1	3.9
Soft tissue	SKUT1	4
Soft tissue	TE125T	3.6
Soft tissue	TE159T	3.5
Soft tissue	TE441T	3.9
Soft tissue	TE617T	3.9
Stomach	2313287	3.7
Stomach	AGS	3.7
Stomach	AZ521	4.2
Stomach	ECC10	3.7
Stomach	ECC12	3.8
Stomach	FU97	7.7
Stomach	GCIY	3.6
Stomach	GSS	4
Stomach	GSU	3.8
Stomach	HGC27	3.5
Stomach	HS746T	3.8
Stomach	HUG1N	3.6
Stomach	IM95	3.7
Stomach	KATOIII	3.8
Stomach	KE39	3.6
Stomach	LMSU	4.2
Stomach	MKN1	4
Stomach	MKN45	3.7
Stomach	MKN74	3.5
Stomach	MKN7	3.6
Stomach	NCCSTCK140	3.7
Stomach	NCIN87	3.6
Stomach	NUGC2	3.7
Stomach	NUGC3	3.8
Stomach	NUGC4	3.6
Stomach	OCUM1	4.1
Stomach	RERFGC1B	3.7
Stomach	SH10TC	3.8
Stomach	SNU16	3.7
Stomach	SNU1	3.9
Stomach	SNU216	3.7
Stomach	SNU520	3.7
Stomach	SNU5	3.8
Stomach	SNU601	3.9
Stomach	SNU620	3.8
Stomach	SNU668	4.2
Stomach	SNU719	3.9
Stomach	TGBC11TKB	3.8
Thyroid	8305C	3.7
Thyroid	8505C	3.3
Thyroid	BCPAP	3.3
Thyroid	BHT101	3.9
Thyroid	CAL62	3.6
Thyroid	CGTHW1	3.9
Thyroid	FTC133	4
Thyroid	FTC238	3.9
Thyroid	ML1	4.2
Thyroid	SW579	3.9
Thyroid	TT2609C02	3.9
Thyroid	TT	7.7
Upper aerodigestive tract	BHY	3.7
Upper aerodigestive tract	BICR16	4.6
Upper aerodigestive tract	BICR18	4
Upper aerodigestive tract	BICR22	3.9
Upper aerodigestive tract	BICR31	6.5
Upper aerodigestive tract	BICR56	3.8
Upper aerodigestive tract	BICR6	3.5
Upper aerodigestive tract	CAL27	3.8
Upper aerodigestive tract	CAL33	3.9
Upper aerodigestive tract	DETROIT562	4
Upper aerodigestive tract	FADU	4
Upper aerodigestive tract	HS840T	3.8
Upper aerodigestive tract	HSC2	3.6
Upper aerodigestive tract	HSC3	3.7
Upper aerodigestive tract	HSC4	3.4
Upper aerodigestive tract	PECAPJ15	3.6
Upper aerodigestive tract	PECAPJ34CLONEC12	4
Upper aerodigestive tract	PECAPJ41CLONED2	4.7
Upper aerodigestive tract	PECAPJ49	4.6
Upper aerodigestive tract	SCC15	3.6
Upper aerodigestive tract	SCC25	3.8
Upper aerodigestive tract	SCC4	4
Upper aerodigestive tract	SCC9	3.7
Upper aerodigestive tract	SNU1076	3.8
Upper aerodigestive tract	SNU1214	3.5
Upper aerodigestive tract	SNU46	3.8
Upper aerodigestive tract	SNU899	3.8
Upper aerodigestive tract	YD10B	3.7
Upper aerodigestive tract	YD38	4
Upper aerodigestive tract	YD8	3.9
Urinary tract	5637	3.7
Urinary tract	639V	3.5
Urinary tract	647V	3.8
Urinary tract	BC3C	3.7
Urinary tract	BFTC905	3.8
Urinary tract	CAL29	3.8
Urinary tract	HS172T	3.7
Urinary tract	HT1197	4
Urinary tract	HT1376	4.2
Urinary tract	J82	3.8
Urinary tract	JMSU1	3.5
Urinary tract	KMBC2	3.7
Urinary tract	KU1919	3.5
Urinary tract	RT11284	4
Urinary tract	RT112	3.8
Urinary tract	RT4	3.7
Urinary tract	SCABER	3.9
Urinary tract	SW1710	3.8
Urinary tract	SW780	3.6
Urinary tract	T24	3.7
Urinary tract	TCCSUP	3.8
Urinary tract	UMUC1	4
Urinary tract	UMUC3	3.9
Urinary tract	VMCUB1	3.7

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Expression Level (TPM)
Adipose tissue	0.1
Adrenal gland	0
Appendix	0.8
Bone marrow	1.9
Breast	0.4
Cerebral cortex	0.2
Cervix, uterine	0.1
Colon	0.1
Duodenum	0.4
Endometrium	0.5
Epididymis	0.2
Esophagus	0
Fallopian tube	0.2
Gallbladder	0.9
Heart muscle	0
Kidney	0.1
Liver	0.1
Lung	0.2
Lymph node	0.6
Ovary	0.2
Pancreas	0
Parathyroid gland	0
Placenta	0.9
Prostate	0.4
Rectum	0.1
Salivary gland	0.1
Seminal vesicle	0.3
Skeletal muscle	0
Skin	0.7
Small intestine	0
Smooth muscle	0.3
Spleen	0.3
Stomach	0.1
Testis	234.6
Thyroid gland	0.4
Tonsil	0.1
Urinary bladder	0.3

> Text Mining based Expression

[ TOP ]

PMID	Expression	Cancer	Evidence
28580303	overexpression	Lung Carcinoma	Aberrant activation of BRDT was first detected in lung cancers.

Summary
Symbol	BRDT
Name	bromodomain testis associated
Aliases	BRD6; CT9; cancer/testis antigen 9; Bromodomain testis-specific protein
Location	1p22.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Somatic copy number alteration in primary tomur tissue

> The Cancer Genome Atlas (TCGA)

[ TOP ]

Correlation between expression and SCNA as well as percentage of patients in different status.

Cancer	Full Name	# Sample	R	P	% Loss	% Neutral	% Gain	Status
BLCA	Bladder urothelial carcinoma	404	0.008	0.879	16.3	63.9	19.8	Neutral
BRCA	Breast invasive carcinoma	1075	-0.037	0.225	32.9	53.4	13.7	Neutral
ESCA	Esophageal carcinoma	183	0.183	0.0133	31.1	57.9	10.9	Neutral
HNSC	Head and Neck squamous cell carcinoma	514	-0.238	4.66e-08	19.3	71.2	9.5	Neutral
LUAD	Lung adenocarcinoma	512	0.129	0.00349	27.5	49.6	22.9	Neutral
LUSC	Lung squamous cell carcinoma	498	0.104	0.0198	39.4	46.8	13.9	Loss
TGCT	Testicular Germ Cell Tumors	150	0.162	0.0481	17.3	54.7	28	Neutral

Summary
Symbol	BRDT
Name	bromodomain testis associated
Aliases	BRD6; CT9; cancer/testis antigen 9; Bromodomain testis-specific protein
Location	1p22.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Methylation level in the promoter region of CR

> Methylation level in the promoter region of CR

[ TOP ]

Correlation between expression and methylation as well as differential methylation analysis.

Cancer	Full Name	R	P	# N	# T	Delta beta (T vs N)	P value (T vs N)	Status
BLCA	Bladder urothelial carcinoma	-0.247	2.62e-07	17	408	0.257	0.00047	Increased
BRCA	Breast invasive carcinoma	-0.028	0.416	83	785	-0.053	2.34e-49	NS/NA
ESCA	Esophageal carcinoma	-0.301	2.25e-05	9	185	NA	NA	NS/NA
HNSC	Head and Neck squamous cell carcinoma	-0.394	0	20	522	-0.23	6.26e-15	Decreased
LUAD	Lung adenocarcinoma	-0.683	0	21	456	-0.159	4.65e-45	NS/NA
LUSC	Lung squamous cell carcinoma	-0.559	0	8	370	NA	NA	NS/NA
TGCT	Testicular Germ Cell Tumors	-0.748	0	0	156	NA	NA	NS/NA

Summary
Symbol	BRDT
Name	bromodomain testis associated
Aliases	BRD6; CT9; cancer/testis antigen 9; Bromodomain testis-specific protein
Location	1p22.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Primary tumor tissue from TCGA > Normal tumor tissue from HPA

>The Cancer Genome Atlas (TCGA) [ TOP ]
There is no record.

> The Human Protein Atlas (HPA)

[ TOP ]

Tissue	Level	Level Name
Adrenal gland	0	Not detected
Appendix	0	Not detected
Bone marrow	0	Not detected
Breast	0	Not detected
Bronchus	0	Not detected
Caudate	0	Not detected
Cerebellum	0	Not detected
Cerebral cortex	0	Not detected
Cervix, uterine	0	Not detected
Colon	0	Not detected
Duodenum	0	Not detected
Endometrium	0	Not detected
Epididymis	0	Not detected
Esophagus	0	Not detected
Fallopian tube	0	Not detected
Gallbladder	0	Not detected
Heart muscle	0	Not detected
Hippocampus	0	Not detected
Kidney	0	Not detected
Liver	0	Not detected
Lung	0	Not detected
Lymph node	0	Not detected
Nasopharynx	0	Not detected
Oral mucosa	0	Not detected
Ovary	0	Not detected
Pancreas	0	Not detected
Placenta	0	Not detected
Prostate	0	Not detected
Rectum	0	Not detected
Salivary gland	0	Not detected
Seminal vesicle	0	Not detected
Skeletal muscle	0	Not detected
Skin	0	Not detected
Small intestine	0	Not detected
Smooth muscle	0	Not detected
Soft tissue	0	Not detected
Spleen	0	Not detected
Stomach	0	Not detected
Testis	3	High
Thyroid gland	0	Not detected
Tonsil	0	Not detected
Urinary bladder	0	Not detected
Vagina	0	Not detected

Summary
Symbol	BRDT
Name	bromodomain testis associated
Aliases	BRD6; CT9; cancer/testis antigen 9; Bromodomain testis-specific protein
Location	1p22.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Association between expresson and subtype > Overall survival analysis based on expression > Association between expresson and stage > Association between expresson and grade

> Subtype

[ TOP ]

Association between expresson and subtype.

Cancer	Full Name	# Patients	P Value (Kruskal-Wallis)	Association	Source
BLCA	Bladder urothelial carcinoma	128	0.758	NS	24476821
BRCA	Breast invasive carcinoma	521	4.45e-18	Significant	23000897
HNSC	Head and Neck squamous cell carcinoma	279	0.177	NS	25631445
LUAD	Lung adenocarcinoma	230	0.124	NS	25079552
LUSC	Lung squamous cell carcinoma	178	0.0769	NS	22960745

> Overall survival

[ TOP ]

Overall survival analysis based on expression.

Cancer	Full Name	# Patients	Hazard Ratio	P Value (Log Rank Test)	Association
BLCA	Bladder urothelial carcinoma	405	0.758	0.19	NS
BRCA	Breast invasive carcinoma	1079	1.286	0.281	NS
ESCA	Esophageal carcinoma	184	1.081	0.821	NS
HNSC	Head and Neck squamous cell carcinoma	518	0.931	0.702	NS
LUAD	Lung adenocarcinoma	502	0.755	0.186	NS
LUSC	Lung squamous cell carcinoma	494	1.116	0.573	NS
TGCT	Testicular Germ Cell Tumors	134	0.695	0.799	NS

> Stage

[ TOP ]

Association between expresson and stage.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
BLCA	Bladder urothelial carcinoma	406	0.017	0.737	NS
BRCA	Breast invasive carcinoma	1071	0.034	0.259	NS
ESCA	Esophageal carcinoma	162	0.093	0.237	NS
HNSC	Head and Neck squamous cell carcinoma	448	0.11	0.0204	Higher
LUAD	Lung adenocarcinoma	507	-0.077	0.0826	NS
LUSC	Lung squamous cell carcinoma	497	0.03	0.503	NS
TGCT	Testicular Germ Cell Tumors	81	-0.021	0.849	NS

> Grade

[ TOP ]

Association between expresson and grade.

Cancer	Full Name	# Patients	R Value (Spearman)	P Value (Spearman)	Association
HNSC	Head and Neck squamous cell carcinoma	498	-0.028	0.529	NS

Summary
Symbol	BRDT
Name	bromodomain testis associated
Aliases	BRD6; CT9; cancer/testis antigen 9; Bromodomain testis-specific protein
Location	1p22.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Targets inferred by reverse engineering method > Targets identified by ChIP-seq data

> Targets inferred by reverse engineering method [ TOP ]

> Targets identified by ChIP-seq data [ TOP ]

Summary
Symbol	BRDT
Name	bromodomain testis associated
Aliases	BRD6; CT9; cancer/testis antigen 9; Bromodomain testis-specific protein
Location	1p22.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Drugs from DrugBank database

> Drugs from DrugBank database [ TOP ]
There is no record for BRDT.

Summary
Symbol	BRDT
Name	bromodomain testis associated
Aliases	BRD6; CT9; cancer/testis antigen 9; Bromodomain testis-specific protein
Location	1p22.1
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Cancer Gene Databases	ONGene (Oncogene) , TSGene (Tumor suppressor gene) , NCG (Network of Cancer Genes)
Content	> Protein-Protein Interaction Network > miRNA Regulatory Relationship > Interactions from Text Mining

> Protein-Protein Interaction Network [ TOP ]

> miRNA Regulatory Relationship [ TOP ]

> Interactions from Text Mining [ TOP ]
There is no record for BRDT.