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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-140-5p SLC2A1 -0.76 0 1.5 0 MirTarget; miRanda; miRNATAP -0.16 0.00012 NA
2 hsa-miR-152-3p SLC2A1 -0.27 0.00639 1.5 0 MirTarget -0.15 0.00079 NA
3 hsa-miR-199a-5p SLC2A1 -0.31 0.00909 1.5 0 miRNATAP -0.18 0 NA
4 hsa-miR-214-5p SLC2A1 0.05 0.67611 1.5 0 miRNATAP -0.11 0.00126 NA
5 hsa-miR-22-3p SLC2A1 -0.51 0 1.5 0 miRNATAP -0.23 0.00016 25304371 In this study we found that GLUT1 is a direct target of miR-22; The ectopic expression of miR-22 inhibited breast cancer cell proliferation and invasion by targeting GLUT1; A reverse correlation between the expression of miR-22 and GLUT1 was observed in breast cancer tissue samples
6 hsa-miR-320a SLC2A1 -0.29 0.00142 1.5 0 miRNAWalker2 validate -0.13 0.00585 NA
7 hsa-miR-378a-3p SLC2A1 -1.8 0 1.5 0 MirTarget -0.15 0 NA
8 hsa-miR-378c SLC2A1 -1.8 0 1.5 0 MirTarget; miRNATAP -0.17 0 NA
9 hsa-miR-491-5p SLC2A1 -1.04 0 1.5 0 miRanda -0.12 0.00013 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 RESPONSE TO OXYGEN CONTAINING COMPOUND 88 1381 4.847e-40 2.255e-36
2 RESPONSE TO ENDOGENOUS STIMULUS 85 1450 8.826e-36 2.053e-32
3 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 92 1848 2.06e-33 3.195e-30
4 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 69 1008 1.225e-32 1.425e-29
5 RESPONSE TO NITROGEN COMPOUND 63 859 2.328e-31 2.167e-28
6 RESPONSE TO HORMONE 63 893 2.131e-30 1.652e-27
7 HOMEOSTATIC PROCESS 74 1337 3.878e-29 2.578e-26
8 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 58 799 1.515e-28 8.81e-26
9 ANION TRANSPORT 47 507 1.189e-27 6.149e-25
10 CHEMICAL HOMEOSTASIS 59 874 2.204e-27 1.026e-24
11 RESPONSE TO ORGANIC CYCLIC COMPOUND 60 917 3.855e-27 1.631e-24
12 RESPONSE TO OXIDATIVE STRESS 40 352 6.237e-27 2.418e-24
13 ION TRANSPORT 68 1262 6.118e-26 2.19e-23
14 RESPONSE TO PEPTIDE 41 404 1.159e-25 3.852e-23
15 CELLULAR RESPONSE TO HORMONE STIMULUS 46 552 4.416e-25 1.37e-22
16 RESPONSE TO OXYGEN LEVELS 36 311 1.448e-24 4.211e-22
17 RESPONSE TO LIPID 56 888 1.725e-24 4.72e-22
18 ORGANIC ANION TRANSPORT 39 387 2.573e-24 6.652e-22
19 NEGATIVE REGULATION OF CELL DEATH 55 872 4.787e-24 1.172e-21
20 RESPONSE TO ABIOTIC STIMULUS 59 1024 7.922e-24 1.843e-21
21 RESPONSE TO INORGANIC SUBSTANCE 42 479 8.961e-24 1.986e-21
22 TRANSMEMBRANE TRANSPORT 59 1098 2.652e-22 5.609e-20
23 CELLULAR RESPONSE TO NITROGEN COMPOUND 41 505 5.929e-22 1.199e-19
24 ORGANIC ACID TRANSPORT 31 261 1.369e-21 2.655e-19
25 REGULATION OF CELL DEATH 67 1472 1.904e-21 3.544e-19
26 RESPONSE TO INSULIN 28 205 2.945e-21 5.271e-19
27 RESPONSE TO REACTIVE OXYGEN SPECIES 27 191 6.203e-21 1.069e-18
28 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 58 1142 1.007e-20 1.673e-18
29 RESPONSE TO DRUG 37 431 1.103e-20 1.77e-18
30 REGULATION OF PHOSPHORUS METABOLIC PROCESS 69 1618 1.498e-20 2.323e-18
31 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 55 1036 1.632e-20 2.373e-18
32 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 55 1036 1.632e-20 2.373e-18
33 POSITIVE REGULATION OF CELL COMMUNICATION 65 1532 3.494e-19 4.927e-17
34 CELLULAR RESPONSE TO OXIDATIVE STRESS 25 184 4.973e-19 6.805e-17
35 RESPONSE TO STEROID HORMONE 37 497 1.337e-18 1.777e-16
36 REGULATION OF CARBOHYDRATE METABOLIC PROCESS 24 172 1.379e-18 1.782e-16
37 SMALL MOLECULE METABOLIC PROCESS 69 1767 1.779e-18 2.237e-16
38 REGULATION OF GLUCOSE METABOLIC PROCESS 20 106 2.379e-18 2.913e-16
39 LIPID METABOLIC PROCESS 55 1158 2.578e-18 3.076e-16
40 CELLULAR HOMEOSTASIS 42 676 3.913e-18 4.552e-16
41 CELLULAR RESPONSE TO PEPTIDE 28 274 7.847e-18 8.906e-16
42 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 59 1395 2.727e-17 3.022e-15
43 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 41 689 4.719e-17 5.106e-15
44 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 46 876 5.626e-17 5.949e-15
45 REGULATION OF MAPK CASCADE 40 660 6.372e-17 6.588e-15
46 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 34 465 6.519e-17 6.594e-15
47 RESPONSE TO EXTERNAL STIMULUS 67 1821 1.368e-16 1.354e-14
48 REGULATION OF CELL DIFFERENTIATION 60 1492 1.449e-16 1.405e-14
49 ION HOMEOSTASIS 37 576 1.658e-16 1.575e-14
50 NEGATIVE REGULATION OF NEURON DEATH 22 171 2.308e-16 2.147e-14
51 ORGANIC ACID METABOLIC PROCESS 47 953 2.769e-16 2.526e-14
52 POSITIVE REGULATION OF CELL PROLIFERATION 43 814 5.498e-16 4.92e-14
53 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 59 1492 5.954e-16 5.227e-14
54 REGULATION OF CELL PROLIFERATION 59 1496 6.722e-16 5.792e-14
55 RESPONSE TO EXTRACELLULAR STIMULUS 32 441 7.157e-16 6.055e-14
56 ANION TRANSMEMBRANE TRANSPORT 25 251 9.088e-16 7.551e-14
57 CELLULAR RESPONSE TO OXYGEN LEVELS 20 143 1.066e-15 8.701e-14
58 RESPONSE TO METAL ION 28 333 1.27e-15 1.019e-13
59 CELLULAR LIPID METABOLIC PROCESS 45 913 1.352e-15 1.066e-13
60 RESPONSE TO HYDROGEN PEROXIDE 18 109 1.473e-15 1.142e-13
61 REGULATION OF LIPID METABOLIC PROCESS 26 282 1.538e-15 1.173e-13
62 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 50 1135 2.441e-15 1.832e-13
63 POSITIVE REGULATION OF MOLECULAR FUNCTION 64 1791 3.273e-15 2.417e-13
64 CELLULAR CHEMICAL HOMEOSTASIS 35 570 4.615e-15 3.355e-13
65 CARDIOVASCULAR SYSTEM DEVELOPMENT 41 788 4.823e-15 3.4e-13
66 CIRCULATORY SYSTEM DEVELOPMENT 41 788 4.823e-15 3.4e-13
67 HEXOSE METABOLIC PROCESS 20 157 6.746e-15 4.685e-13
68 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 19 138 7.615e-15 5.152e-13
69 RESPONSE TO PURINE CONTAINING COMPOUND 20 158 7.64e-15 5.152e-13
70 MONOSACCHARIDE METABOLIC PROCESS 22 202 8.058e-15 5.356e-13
71 POSITIVE REGULATION OF RESPONSE TO STIMULUS 66 1929 8.69e-15 5.695e-13
72 REGULATION OF CARBOHYDRATE BIOSYNTHETIC PROCESS 16 87 9.769e-15 6.314e-13
73 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 44 926 1.083e-14 6.905e-13
74 REGULATION OF KINASE ACTIVITY 40 776 1.477e-14 9.289e-13
75 REGULATION OF PROTEIN MODIFICATION PROCESS 61 1710 1.907e-14 1.183e-12
76 CELLULAR RESPONSE TO STRESS 58 1565 1.936e-14 1.185e-12
77 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 32 498 2.18e-14 1.317e-12
78 LIPID LOCALIZATION 24 264 2.724e-14 1.625e-12
79 REGULATION OF RESPONSE TO WOUNDING 29 413 4.186e-14 2.466e-12
80 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 19 152 4.643e-14 2.7e-12
81 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 59 1656 6.092e-14 3.499e-12
82 ORGANIC HYDROXY COMPOUND TRANSPORT 19 155 6.67e-14 3.785e-12
83 OXIDATION REDUCTION PROCESS 42 898 8.137e-14 4.562e-12
84 GLUCOSE METABOLIC PROCESS 17 119 1.108e-13 6.136e-12
85 POSITIVE REGULATION OF MAPK CASCADE 30 470 1.797e-13 9.832e-12
86 CELLULAR RESPONSE TO REACTIVE OXYGEN SPECIES 16 104 1.817e-13 9.832e-12
87 MONOCARBOXYLIC ACID TRANSPORT 17 124 2.221e-13 1.188e-11
88 RESPONSE TO GROWTH FACTOR 30 475 2.363e-13 1.249e-11
89 TISSUE DEVELOPMENT 55 1518 2.731e-13 1.428e-11
90 CELLULAR RESPONSE TO INSULIN STIMULUS 18 146 2.804e-13 1.45e-11
91 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 58 1672 3.27e-13 1.672e-11
92 POSITIVE REGULATION OF KINASE ACTIVITY 30 482 3.447e-13 1.743e-11
93 GLYCEROLIPID METABOLIC PROCESS 26 356 3.808e-13 1.885e-11
94 CARBOHYDRATE METABOLIC PROCESS 35 662 3.8e-13 1.885e-11
95 REGULATION OF TRANSFERASE ACTIVITY 42 946 4.611e-13 2.259e-11
96 POSITIVE REGULATION OF CELL DIFFERENTIATION 39 823 4.718e-13 2.287e-11
97 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 13 62 5.506e-13 2.641e-11
98 BLOOD VESSEL MORPHOGENESIS 26 364 6.355e-13 3.017e-11
99 REGULATION OF NEURON DEATH 22 252 7.73e-13 3.633e-11
100 MONOCARBOXYLIC ACID METABOLIC PROCESS 30 503 1.028e-12 4.767e-11
101 VASCULATURE DEVELOPMENT 29 469 1.035e-12 4.767e-11
102 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 63 1977 1.052e-12 4.8e-11
103 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 33 616 1.335e-12 6.029e-11
104 RESPONSE TO ORGANOPHOSPHORUS 17 139 1.495e-12 6.687e-11
105 LIPID MODIFICATION 20 210 1.767e-12 7.831e-11
106 REGULATION OF LIPID STORAGE 11 41 1.859e-12 8.161e-11
107 CELLULAR RESPONSE TO EXTERNAL STIMULUS 22 264 1.973e-12 8.579e-11
108 ANGIOGENESIS 23 293 2.107e-12 9.079e-11
109 REGULATION OF TRANSPORT 59 1804 2.332e-12 9.955e-11
110 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 59 1805 2.386e-12 1.009e-10
111 SINGLE ORGANISM CATABOLIC PROCESS 41 957 2.855e-12 1.197e-10
112 PHOSPHORYLATION 47 1228 3.14e-12 1.304e-10
113 REGULATION OF FATTY ACID METABOLIC PROCESS 14 87 3.226e-12 1.328e-10
114 CELLULAR RESPONSE TO LIPID 28 457 3.26e-12 1.331e-10
115 POSITIVE REGULATION OF CATALYTIC ACTIVITY 53 1518 3.441e-12 1.392e-10
116 RESPONSE TO ALCOHOL 25 362 3.806e-12 1.527e-10
117 REGULATION OF CELLULAR COMPONENT MOVEMENT 36 771 6.351e-12 2.509e-10
118 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 28 470 6.364e-12 2.509e-10
119 POSITIVE REGULATION OF CARBOHYDRATE METABOLIC PROCESS 13 75 7.279e-12 2.846e-10
120 ION TRANSMEMBRANE TRANSPORT 37 822 9.126e-12 3.539e-10
121 REGULATION OF HORMONE LEVELS 28 478 9.495e-12 3.651e-10
122 CELLULAR RESPONSE TO INORGANIC SUBSTANCE 17 156 9.901e-12 3.776e-10
123 RESPONSE TO ACID CHEMICAL 23 319 1.208e-11 4.571e-10
124 RESPONSE TO MECHANICAL STIMULUS 19 210 1.599e-11 5.999e-10
125 PEPTIDYL TYROSINE MODIFICATION 18 186 1.804e-11 6.713e-10
126 SINGLE ORGANISM BIOSYNTHETIC PROCESS 48 1340 1.841e-11 6.799e-10
127 REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 12 65 2.176e-11 7.971e-10
128 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 14 100 2.286e-11 8.31e-10
129 POSITIVE REGULATION OF TRANSPORT 39 936 2.414e-11 8.707e-10
130 RESPONSE TO ESTROGEN 19 218 3.077e-11 1.101e-09
131 ORGANIC ACID TRANSMEMBRANE TRANSPORT 14 103 3.445e-11 1.224e-09
132 NITROGEN COMPOUND TRANSPORT 28 507 3.785e-11 1.314e-09
133 REGULATION OF SYSTEM PROCESS 28 507 3.785e-11 1.314e-09
134 INOSITOL LIPID MEDIATED SIGNALING 15 124 3.739e-11 1.314e-09
135 REGULATION OF NITRIC OXIDE BIOSYNTHETIC PROCESS 11 53 3.937e-11 1.337e-09
136 RESPONSE TO CAMP 14 104 3.937e-11 1.337e-09
137 REGULATION OF RESPONSE TO STRESS 50 1468 3.929e-11 1.337e-09
138 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 13 86 4.438e-11 1.496e-09
139 CATION TRANSPORT 35 796 6.746e-11 2.258e-09
140 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 22 321 9.205e-11 3.059e-09
141 GENERATION OF PRECURSOR METABOLITES AND ENERGY 21 292 1.03e-10 3.398e-09
142 NEGATIVE REGULATION OF PHOSPHORYLATION 25 422 1.038e-10 3.4e-09
143 IMMUNE SYSTEM PROCESS 59 1984 1.118e-10 3.638e-09
144 PROTEIN PHOSPHORYLATION 38 944 1.221e-10 3.944e-09
145 NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS 15 135 1.278e-10 4.101e-09
146 UROGENITAL SYSTEM DEVELOPMENT 21 299 1.597e-10 5.089e-09
147 REGULATION OF LIPID TRANSPORT 13 95 1.613e-10 5.105e-09
148 RESPONSE TO TOXIC SUBSTANCE 19 241 1.741e-10 5.474e-09
149 MONOVALENT INORGANIC CATION TRANSPORT 25 435 1.966e-10 6.14e-09
150 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 18 218 2.516e-10 7.805e-09
151 SMALL MOLECULE BIOSYNTHETIC PROCESS 25 443 2.88e-10 8.874e-09
152 PEPTIDYL AMINO ACID MODIFICATION 35 841 2.977e-10 9.113e-09
153 REGULATION OF MEMBRANE POTENTIAL 22 343 3.266e-10 9.933e-09
154 GLUCOSE HOMEOSTASIS 16 170 3.732e-10 1.12e-08
155 CARBOHYDRATE HOMEOSTASIS 16 170 3.732e-10 1.12e-08
156 POSITIVE REGULATION OF GLUCOSE METABOLIC PROCESS 9 36 4.067e-10 1.213e-08
157 REGULATION OF COENZYME METABOLIC PROCESS 10 50 4.582e-10 1.349e-08
158 REGULATION OF COFACTOR METABOLIC PROCESS 10 50 4.582e-10 1.349e-08
159 EPITHELIUM DEVELOPMENT 37 945 4.778e-10 1.398e-08
160 REGULATION OF CELLULAR KETONE METABOLIC PROCESS 16 173 4.841e-10 1.408e-08
161 REGULATION OF CATABOLIC PROCESS 32 731 5.373e-10 1.553e-08
162 POSITIVE REGULATION OF LIPID METABOLIC PROCESS 14 128 6.624e-10 1.903e-08
163 NEGATIVE REGULATION OF LIPID STORAGE 7 17 7.046e-10 2.011e-08
164 REGULATION OF INFLAMMATORY RESPONSE 20 294 7.758e-10 2.201e-08
165 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 27 541 8.15e-10 2.285e-08
166 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 27 541 8.15e-10 2.285e-08
167 REGULATION OF BODY FLUID LEVELS 26 506 9.265e-10 2.581e-08
168 REGULATION OF IMMUNE SYSTEM PROCESS 46 1403 9.513e-10 2.635e-08
169 REGULATION OF GENERATION OF PRECURSOR METABOLITES AND ENERGY 12 89 9.871e-10 2.718e-08
170 RESPONSE TO KETONE 16 182 1.024e-09 2.803e-08
171 REGULATION OF ERK1 AND ERK2 CASCADE 18 238 1.044e-09 2.842e-08
172 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 14 133 1.104e-09 2.986e-08
173 SECRETION 28 588 1.111e-09 2.988e-08
174 ORGANOPHOSPHATE METABOLIC PROCESS 35 885 1.148e-09 3.07e-08
175 REGULATION OF MACROPHAGE DERIVED FOAM CELL DIFFERENTIATION 8 28 1.213e-09 3.226e-08
176 POSITIVE REGULATION OF GENE EXPRESSION 52 1733 1.392e-09 3.68e-08
177 CELLULAR RESPONSE TO EXTRACELLULAR STIMULUS 16 188 1.648e-09 4.332e-08
178 REGULATION OF NEURON APOPTOTIC PROCESS 16 192 2.24e-09 5.824e-08
179 PROTEIN AUTOPHOSPHORYLATION 16 192 2.24e-09 5.824e-08
180 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 36 957 2.455e-09 6.345e-08
181 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 37 1004 2.495e-09 6.413e-08
182 SINGLE ORGANISM BEHAVIOR 22 384 2.698e-09 6.897e-08
183 POSITIVE REGULATION OF LOCOMOTION 23 420 2.742e-09 6.971e-08
184 CARBOHYDRATE BIOSYNTHETIC PROCESS 13 121 3.414e-09 8.587e-08
185 REGULATION OF PROTEIN KINASE B SIGNALING 13 121 3.414e-09 8.587e-08
186 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 19 289 3.674e-09 9.192e-08
187 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 52 1784 3.781e-09 9.409e-08
188 IMMUNE SYSTEM DEVELOPMENT 27 582 3.935e-09 9.654e-08
189 INTRACELLULAR SIGNAL TRANSDUCTION 48 1572 3.942e-09 9.654e-08
190 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 37 1021 3.915e-09 9.654e-08
191 MONOVALENT INORGANIC CATION HOMEOSTASIS 13 123 4.181e-09 1.019e-07
192 RESPONSE TO TRANSITION METAL NANOPARTICLE 14 148 4.504e-09 1.091e-07
193 CELL DEVELOPMENT 45 1426 4.901e-09 1.182e-07
194 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 32 801 5.011e-09 1.202e-07
195 SMALL MOLECULE CATABOLIC PROCESS 20 328 5.118e-09 1.221e-07
196 RESPONSE TO CORTICOSTEROID 15 176 5.29e-09 1.234e-07
197 REGULATION OF DEFENSE RESPONSE 31 759 5.321e-09 1.234e-07
198 REGULATION OF CELLULAR LOCALIZATION 42 1277 5.307e-09 1.234e-07
199 NEGATIVE REGULATION OF MACROPHAGE DERIVED FOAM CELL DIFFERENTIATION 6 13 5.33e-09 1.234e-07
200 REGULATION OF CHOLESTEROL STORAGE 6 13 5.33e-09 1.234e-07
201 REGULATION OF VASCULATURE DEVELOPMENT 17 233 5.303e-09 1.234e-07
202 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 9 48 6.369e-09 1.467e-07
203 RESPONSE TO STARVATION 14 154 7.547e-09 1.73e-07
204 NEUTRAL LIPID METABOLIC PROCESS 11 85 7.785e-09 1.776e-07
205 RESPONSE TO WOUNDING 26 563 8.552e-09 1.941e-07
206 MULTICELLULAR ORGANISMAL HOMEOSTASIS 18 272 8.661e-09 1.956e-07
207 VASCULAR ENDOTHELIAL GROWTH FACTOR SIGNALING PATHWAY 6 14 9.231e-09 2.055e-07
208 SECRETION BY CELL 24 486 9.213e-09 2.055e-07
209 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 33 867 9.215e-09 2.055e-07
210 HORMONE MEDIATED SIGNALING PATHWAY 14 158 1.051e-08 2.329e-07
211 LIPID HOMEOSTASIS 12 110 1.164e-08 2.554e-07
212 POSITIVE REGULATION OF SYNAPTIC TRANSMISSION 12 110 1.164e-08 2.554e-07
213 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 27 616 1.303e-08 2.847e-07
214 NEGATIVE REGULATION OF TRANSPORT 23 458 1.398e-08 3.04e-07
215 POSITIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 14 162 1.449e-08 3.137e-07
216 RESPONSE TO ALKALOID 13 137 1.562e-08 3.364e-07
217 RESPONSE TO NUTRIENT 15 191 1.609e-08 3.449e-07
218 REGULATION OF STEROL TRANSPORT 8 38 1.716e-08 3.63e-07
219 REGULATION OF CHOLESTEROL TRANSPORT 8 38 1.716e-08 3.63e-07
220 REGULATION OF GLUCONEOGENESIS 8 38 1.716e-08 3.63e-07
221 DEVELOPMENTAL MATURATION 15 193 1.851e-08 3.897e-07
222 RESPONSE TO CYTOKINE 29 714 1.955e-08 4.098e-07
223 REGULATED EXOCYTOSIS 16 224 2.042e-08 4.262e-07
224 POSITIVE REGULATION OF STAT CASCADE 10 73 2.162e-08 4.47e-07
225 POSITIVE REGULATION OF JAK STAT CASCADE 10 73 2.162e-08 4.47e-07
226 NEGATIVE REGULATION OF CELL COMMUNICATION 39 1192 2.342e-08 4.822e-07
227 TUBE DEVELOPMENT 25 552 2.468e-08 5.059e-07
228 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 8 40 2.642e-08 5.368e-07
229 FATTY ACID TRANSPORT 9 56 2.64e-08 5.368e-07
230 CELL DEATH 35 1001 2.664e-08 5.389e-07
231 PHOSPHOLIPID METABOLIC PROCESS 20 364 2.941e-08 5.923e-07
232 FATTY ACID METABOLIC PROCESS 18 296 3.2e-08 6.417e-07
233 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 42 1360 3.223e-08 6.436e-07
234 GLYCEROPHOSPHOLIPID METABOLIC PROCESS 18 297 3.369e-08 6.699e-07
235 ORGANIC HYDROXY COMPOUND METABOLIC PROCESS 23 482 3.582e-08 7.093e-07
236 POSITIVE REGULATION OF CELL DEATH 26 605 3.663e-08 7.221e-07
237 REGULATION OF FATTY ACID OXIDATION 7 28 3.82e-08 7.5e-07
238 CELLULAR RESPONSE TO ACID CHEMICAL 14 175 3.872e-08 7.57e-07
239 LIPID PHOSPHORYLATION 11 99 3.951e-08 7.692e-07
240 MODULATION OF SYNAPTIC TRANSMISSION 18 301 4.132e-08 8.011e-07
241 NEGATIVE REGULATION OF CELL DIFFERENTIATION 26 609 4.177e-08 8.065e-07
242 CELL ACTIVATION 25 568 4.301e-08 8.271e-07
243 RESPONSE TO BACTERIUM 24 528 4.462e-08 8.544e-07
244 REGULATION OF SECRETION 28 699 4.685e-08 8.935e-07
245 REGULATION OF OSSIFICATION 14 178 4.798e-08 9.113e-07
246 REGULATION OF GLUCOSE IMPORT 9 60 4.935e-08 9.335e-07
247 REGULATION OF PHOSPHOLIPID METABOLIC PROCESS 9 61 5.728e-08 1.075e-06
248 CELLULAR RESPONSE TO HYDROGEN PEROXIDE 9 61 5.728e-08 1.075e-06
249 DIVALENT INORGANIC CATION HOMEOSTASIS 19 343 5.809e-08 1.085e-06
250 REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 15 213 6.887e-08 1.282e-06
251 SYSTEM PROCESS 49 1785 7.808e-08 1.447e-06
252 DRUG TRANSMEMBRANE TRANSPORT 6 19 7.919e-08 1.462e-06
253 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 37 1152 9.017e-08 1.658e-06
254 COGNITION 16 251 9.972e-08 1.827e-06
255 POSITIVE REGULATION OF LIPID KINASE ACTIVITY 7 32 1.041e-07 1.9e-06
256 POSITIVE REGULATION OF CATABOLIC PROCESS 20 395 1.12e-07 2.029e-06
257 REGULATION OF TYROSINE PHOSPHORYLATION OF STAT5 PROTEIN 6 20 1.12e-07 2.029e-06
258 REGULATION OF LIPID KINASE ACTIVITY 8 48 1.19e-07 2.147e-06
259 POSITIVE REGULATION OF FATTY ACID METABOLIC PROCESS 7 33 1.308e-07 2.349e-06
260 PHOSPHATIDYLINOSITOL METABOLIC PROCESS 14 193 1.318e-07 2.352e-06
261 AMINO ACID TRANSMEMBRANE TRANSPORT 9 67 1.324e-07 2.352e-06
262 REGULATION OF DNA TEMPLATED TRANSCRIPTION IN RESPONSE TO STRESS 9 67 1.324e-07 2.352e-06
263 REGULATION OF HYDROLASE ACTIVITY 40 1327 1.376e-07 2.435e-06
264 REGULATION OF NUCLEOSIDE METABOLIC PROCESS 8 49 1.408e-07 2.472e-06
265 REGULATION OF ATP METABOLIC PROCESS 8 49 1.408e-07 2.472e-06
266 REGULATION OF TYROSINE PHOSPHORYLATION OF STAT PROTEIN 9 68 1.51e-07 2.641e-06
267 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 28 740 1.526e-07 2.659e-06
268 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 20 404 1.611e-07 2.797e-06
269 RESPONSE TO FLUID SHEAR STRESS 7 34 1.629e-07 2.818e-06
270 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 33 983 1.786e-07 3.078e-06
271 REGULATION OF HORMONE SECRETION 16 262 1.793e-07 3.079e-06
272 REGULATION OF BLOOD PRESSURE 13 169 1.891e-07 3.235e-06
273 AGING 16 264 1.988e-07 3.389e-06
274 CELLULAR RESPONSE TO STARVATION 11 117 2.237e-07 3.8e-06
275 CELLULAR CARBOHYDRATE METABOLIC PROCESS 12 144 2.368e-07 3.992e-06
276 SODIUM ION TRANSPORT 12 144 2.368e-07 3.992e-06
277 NEGATIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 7 36 2.476e-07 4.159e-06
278 RESPONSE TO ESTRADIOL 12 146 2.752e-07 4.607e-06
279 RESPONSE TO INCREASED OXYGEN LEVELS 6 23 2.827e-07 4.697e-06
280 RESPONSE TO HYPEROXIA 6 23 2.827e-07 4.697e-06
281 IMPORT INTO CELL 7 37 3.021e-07 5.003e-06
282 REACTIVE OXYGEN SPECIES METABOLIC PROCESS 10 96 3.061e-07 5.051e-06
283 MONOSACCHARIDE BIOSYNTHETIC PROCESS 8 54 3.079e-07 5.063e-06
284 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 16 274 3.287e-07 5.386e-06
285 REGULATION OF ION TRANSPORT 24 592 3.661e-07 5.978e-06
286 POSITIVE REGULATION OF NUCLEOSIDE METABOLIC PROCESS 6 24 3.73e-07 6.026e-06
287 POSITIVE REGULATION OF ATP METABOLIC PROCESS 6 24 3.73e-07 6.026e-06
288 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 10 98 3.72e-07 6.026e-06
289 REGULATION OF NUCLEOTIDE METABOLIC PROCESS 14 211 3.936e-07 6.337e-06
290 AMINO ACID TRANSPORT 11 124 4.042e-07 6.486e-06
291 WOUND HEALING 21 470 4.278e-07 6.841e-06
292 KIDNEY EPITHELIUM DEVELOPMENT 11 125 4.385e-07 6.987e-06
293 AMMONIUM TRANSPORT 8 57 4.737e-07 7.522e-06
294 DRUG TRANSPORT 6 25 4.858e-07 7.688e-06
295 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 12 154 4.906e-07 7.738e-06
296 NEGATIVE REGULATION OF MOLECULAR FUNCTION 34 1079 4.961e-07 7.784e-06
297 BEHAVIOR 22 516 4.968e-07 7.784e-06
298 POSITIVE REGULATION OF FATTY ACID OXIDATION 5 14 5.044e-07 7.875e-06
299 REGULATION OF MAP KINASE ACTIVITY 17 319 5.084e-07 7.911e-06
300 RENAL SYSTEM PROCESS 10 102 5.419e-07 8.404e-06
301 ENERGY DERIVATION BY OXIDATION OF ORGANIC COMPOUNDS 14 217 5.527e-07 8.544e-06
302 RESPONSE TO BIOTIC STIMULUS 30 886 5.709e-07 8.797e-06
303 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 10 103 5.937e-07 9.117e-06
304 STEROL HOMEOSTASIS 8 59 6.223e-07 9.463e-06
305 CHOLESTEROL HOMEOSTASIS 8 59 6.223e-07 9.463e-06
306 ORGAN MORPHOGENESIS 29 841 6.191e-07 9.463e-06
307 INSULIN RECEPTOR SIGNALING PATHWAY 9 80 6.247e-07 9.468e-06
308 REGULATION OF APOPTOTIC SIGNALING PATHWAY 18 363 6.675e-07 1.008e-05
309 REGULATION OF CELL ACTIVATION 21 484 6.889e-07 1.037e-05
310 POSITIVE REGULATION OF PROTEIN KINASE B SIGNALING 9 81 6.953e-07 1.044e-05
311 LEARNING 11 131 7.03e-07 1.052e-05
312 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 8 60 7.104e-07 1.06e-05
313 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 18 365 7.227e-07 1.074e-05
314 CIRCULATORY SYSTEM PROCESS 18 366 7.518e-07 1.097e-05
315 NEUROTRANSMITTER UPTAKE 5 15 7.489e-07 1.097e-05
316 POSITIVE REGULATION OF PHOSPHOLIPID METABOLIC PROCESS 7 42 7.512e-07 1.097e-05
317 REGULATION OF CELLULAR CARBOHYDRATE CATABOLIC PROCESS 7 42 7.512e-07 1.097e-05
318 LONG CHAIN FATTY ACID TRANSPORT 7 42 7.512e-07 1.097e-05
319 REGULATION OF CARBOHYDRATE CATABOLIC PROCESS 7 42 7.512e-07 1.097e-05
320 FAT CELL DIFFERENTIATION 10 106 7.761e-07 1.129e-05
321 REGENERATION 12 161 7.904e-07 1.146e-05
322 REGULATION OF HOMEOSTATIC PROCESS 20 447 7.968e-07 1.151e-05
323 REGULATION OF PROTEIN LOCALIZATION 31 950 8.01e-07 1.154e-05
324 MEMBRANE DEPOLARIZATION 8 61 8.09e-07 1.162e-05
325 REGULATION OF INTRACELLULAR TRANSPORT 24 621 8.592e-07 1.23e-05
326 POSITIVE REGULATION OF SECRETION 18 370 8.791e-07 1.251e-05
327 REGULATION OF BLOOD CIRCULATION 16 295 8.795e-07 1.251e-05
328 RESPONSE TO COLD 7 43 8.878e-07 1.259e-05
329 METAL ION TRANSPORT 23 582 1.006e-06 1.419e-05
330 RHYTHMIC PROCESS 16 298 1.005e-06 1.419e-05
331 BICARBONATE TRANSPORT 7 44 1.045e-06 1.468e-05
332 CATABOLIC PROCESS 46 1773 1.048e-06 1.468e-05
333 POSITIVE REGULATION OF TYROSINE PHOSPHORYLATION OF STAT5 PROTEIN 5 16 1.078e-06 1.507e-05
334 RESPONSE TO CARBOHYDRATE 12 168 1.243e-06 1.731e-05
335 CARBOXYLIC ACID BIOSYNTHETIC PROCESS 15 270 1.443e-06 1.998e-05
336 ORGANIC ACID BIOSYNTHETIC PROCESS 15 270 1.443e-06 1.998e-05
337 ORGANONITROGEN COMPOUND METABOLIC PROCESS 46 1796 1.494e-06 2.063e-05
338 POSITIVE REGULATION OF STEROL TRANSPORT 5 17 1.512e-06 2.067e-05
339 POSITIVE REGULATION OF GLYCOGEN METABOLIC PROCESS 5 17 1.512e-06 2.067e-05
340 HEART DEVELOPMENT 20 466 1.514e-06 2.067e-05
341 POSITIVE REGULATION OF CHOLESTEROL TRANSPORT 5 17 1.512e-06 2.067e-05
342 REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION 13 203 1.534e-06 2.088e-05
343 CELLULAR RESPONSE TO VASCULAR ENDOTHELIAL GROWTH FACTOR STIMULUS 6 30 1.547e-06 2.098e-05
344 REGULATION OF PH 9 89 1.555e-06 2.103e-05
345 POSITIVE REGULATION OF ERK1 AND ERK2 CASCADE 12 172 1.593e-06 2.149e-05
346 REPRODUCTION 37 1297 1.621e-06 2.18e-05
347 CELLULAR RESPONSE TO ALCOHOL 10 115 1.648e-06 2.21e-05
348 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 8 67 1.681e-06 2.239e-05
349 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 33 1087 1.684e-06 2.239e-05
350 EXOCYTOSIS 16 310 1.684e-06 2.239e-05
351 REGULATION OF OXIDOREDUCTASE ACTIVITY 9 90 1.709e-06 2.266e-05
352 REGULATION OF CELL DEVELOPMENT 28 836 1.732e-06 2.29e-05
353 REGULATION OF JAK STAT CASCADE 11 144 1.8e-06 2.339e-05
354 REGULATION OF PROTEIN SECRETION 18 389 1.795e-06 2.339e-05
355 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 11 144 1.8e-06 2.339e-05
356 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 23 602 1.785e-06 2.339e-05
357 REGULATION OF RESPONSE TO CYTOKINE STIMULUS 11 144 1.8e-06 2.339e-05
358 REGULATION OF STAT CASCADE 11 144 1.8e-06 2.339e-05
359 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 8 68 1.885e-06 2.443e-05
360 L ALPHA AMINO ACID TRANSMEMBRANE TRANSPORT 6 31 1.898e-06 2.453e-05
361 NEGATIVE REGULATION OF MAPK CASCADE 11 145 1.926e-06 2.483e-05
362 RESPONSE TO CAFFEINE 5 18 2.073e-06 2.665e-05
363 RESPONSE TO ACTIVITY 8 69 2.11e-06 2.705e-05
364 PHOSPHATIDYLINOSITOL 3 PHOSPHATE BIOSYNTHETIC PROCESS 7 49 2.222e-06 2.833e-05
365 REGULATION OF SMOOTH MUSCLE CELL MIGRATION 7 49 2.222e-06 2.833e-05
366 GLAND DEVELOPMENT 18 395 2.228e-06 2.833e-05
367 GLYCEROLIPID BIOSYNTHETIC PROCESS 13 211 2.36e-06 2.976e-05
368 RESPONSE TO TEMPERATURE STIMULUS 11 148 2.355e-06 2.976e-05
369 LIPID OXIDATION 8 70 2.357e-06 2.976e-05
370 CELLULAR RESPONSE TO CAMP 7 50 2.557e-06 3.215e-05
371 MULTI MULTICELLULAR ORGANISM PROCESS 13 213 2.62e-06 3.286e-05
372 POSITIVE REGULATION OF HYDROLASE ACTIVITY 29 905 2.678e-06 3.349e-05
373 NEGATIVE REGULATION OF GENE EXPRESSION 40 1493 2.756e-06 3.438e-05
374 GAS TRANSPORT 5 19 2.785e-06 3.456e-05
375 CELLULAR RESPONSE TO REACTIVE NITROGEN SPECIES 5 19 2.785e-06 3.456e-05
376 NEURON PROJECTION REGENERATION 6 33 2.797e-06 3.461e-05
377 REGULATION OF EPITHELIAL CELL PROLIFERATION 15 285 2.815e-06 3.474e-05
378 POSITIVE REGULATION OF LIPID TRANSPORT 7 51 2.933e-06 3.601e-05
379 CELLULAR CARBOHYDRATE BIOSYNTHETIC PROCESS 7 51 2.933e-06 3.601e-05
380 CELLULAR MONOVALENT INORGANIC CATION HOMEOSTASIS 9 96 2.943e-06 3.603e-05
381 CELLULAR RESPONSE TO KETONE 8 73 3.251e-06 3.97e-05
382 NEGATIVE REGULATION OF ERK1 AND ERK2 CASCADE 7 52 3.354e-06 4.074e-05
383 REGULATION OF CELLULAR COMPONENT BIOGENESIS 26 767 3.354e-06 4.074e-05
384 REPRODUCTIVE SYSTEM DEVELOPMENT 18 408 3.506e-06 4.248e-05
385 STEROID HORMONE MEDIATED SIGNALING PATHWAY 10 125 3.522e-06 4.256e-05
386 GLYCOSYL COMPOUND METABOLIC PROCESS 17 368 3.578e-06 4.313e-05
387 HYDROGEN PEROXIDE CATABOLIC PROCESS 5 20 3.676e-06 4.42e-05
388 LIPID BIOSYNTHETIC PROCESS 21 539 3.783e-06 4.537e-05
389 CENTRAL NERVOUS SYSTEM DEVELOPMENT 28 872 3.881e-06 4.642e-05
390 REGULATION OF HEART CONTRACTION 13 221 3.932e-06 4.679e-05
391 NEGATIVE REGULATION OF RESPONSE TO WOUNDING 11 156 3.931e-06 4.679e-05
392 REGULATION OF GLYCOGEN METABOLIC PROCESS 6 35 4.015e-06 4.765e-05
393 REGULATION OF GLUCOSE TRANSPORT 9 100 4.136e-06 4.897e-05
394 REGULATION OF NEUROTRANSMITTER LEVELS 12 190 4.494e-06 5.307e-05
395 REGULATION OF NUCLEOTIDE CATABOLIC PROCESS 6 36 4.768e-06 5.598e-05
396 REGULATION OF RECEPTOR BIOSYNTHETIC PROCESS 5 21 4.776e-06 5.598e-05
397 NEGATIVE REGULATION OF PROTEIN ACETYLATION 5 21 4.776e-06 5.598e-05
398 DETOXIFICATION 8 77 4.877e-06 5.702e-05
399 CELL MOTILITY 27 835 5.147e-06 5.987e-05
400 LOCALIZATION OF CELL 27 835 5.147e-06 5.987e-05
401 POSITIVE REGULATION OF TYROSINE PHOSPHORYLATION OF STAT3 PROTEIN 6 37 5.632e-06 6.536e-05
402 RESPONSE TO IMMOBILIZATION STRESS 5 22 6.119e-06 7.083e-05
403 HORMONE METABOLIC PROCESS 11 164 6.363e-06 7.347e-05
404 REGULATION OF FAT CELL DIFFERENTIATION 9 106 6.697e-06 7.713e-05
405 REGULATION OF TRANSPORTER ACTIVITY 12 198 6.858e-06 7.879e-05
406 NEGATIVE REGULATION OF PROTEIN AUTOPHOSPHORYLATION 4 11 6.999e-06 7.995e-05
407 POSITIVE REGULATION OF CELL DEVELOPMENT 19 472 7.01e-06 7.995e-05
408 RESPONSE TO TUMOR NECROSIS FACTOR 13 233 6.992e-06 7.995e-05
409 L AMINO ACID TRANSPORT 7 58 7.077e-06 8.032e-05
410 CELLULAR RESPONSE TO CORTICOSTEROID STIMULUS 7 58 7.077e-06 8.032e-05
411 PHENOL CONTAINING COMPOUND METABOLIC PROCESS 8 81 7.146e-06 8.07e-05
412 REGULATION OF EPITHELIAL CELL MIGRATION 11 166 7.146e-06 8.07e-05
413 PLATELET DEGRANULATION 9 107 7.234e-06 8.15e-05
414 NEGATIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 12 200 7.597e-06 8.538e-05
415 REGULATION OF PHOSPHOLIPASE C ACTIVITY 6 39 7.743e-06 8.64e-05
416 LONG TERM SYNAPTIC POTENTIATION 6 39 7.743e-06 8.64e-05
417 PEPTIDYL TYROSINE AUTOPHOSPHORYLATION 6 39 7.743e-06 8.64e-05
418 INTRACELLULAR RECEPTOR SIGNALING PATHWAY 11 168 8.01e-06 8.917e-05
419 PROTEIN OLIGOMERIZATION 18 434 8.205e-06 9.111e-05
420 HEAD DEVELOPMENT 24 709 8.35e-06 9.251e-05
421 REGULATION OF ANION TRANSPORT 10 138 8.534e-06 9.431e-05
422 REGULATION OF LIPASE ACTIVITY 8 83 8.579e-06 9.437e-05
423 RESPONSE TO FATTY ACID 8 83 8.579e-06 9.437e-05
424 REGULATION OF MONOOXYGENASE ACTIVITY 7 60 8.902e-06 9.769e-05
425 DEFENSE RESPONSE 34 1231 8.993e-06 9.846e-05
426 CELLULAR ALDEHYDE METABOLIC PROCESS 8 84 9.382e-06 0.0001022
427 POSITIVE REGULATION OF OSSIFICATION 8 84 9.382e-06 0.0001022
428 CARBOXYLIC ACID CATABOLIC PROCESS 12 205 9.759e-06 0.0001058
429 ORGANIC ACID CATABOLIC PROCESS 12 205 9.759e-06 0.0001058
430 REGULATION OF SEQUESTERING OF TRIGLYCERIDE 4 12 1.04e-05 0.0001122
431 POSITIVE REGULATION OF INSULIN RECEPTOR SIGNALING PATHWAY 4 12 1.04e-05 0.0001122
432 CELL PROLIFERATION 23 672 1.089e-05 0.0001173
433 PLATELET ACTIVATION 10 142 1.098e-05 0.000118
434 POSITIVE REGULATION OF NUCLEAR DIVISION 7 62 1.11e-05 0.000119
435 OVULATION CYCLE 9 113 1.13e-05 0.0001208
436 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 24 724 1.181e-05 0.0001257
437 HOMEOSTASIS OF NUMBER OF CELLS 11 175 1.18e-05 0.0001257
438 REGULATION OF ENDOTHELIAL CELL MIGRATION 9 114 1.213e-05 0.0001289
439 INORGANIC ION TRANSMEMBRANE TRANSPORT 21 583 1.251e-05 0.0001326
440 MYELOID CELL HOMEOSTASIS 8 88 1.326e-05 0.00014
441 ANATOMICAL STRUCTURE HOMEOSTASIS 14 285 1.327e-05 0.00014
442 REGULATION OF METAL ION TRANSPORT 15 325 1.367e-05 0.0001439
443 REGULATION OF PHOSPHOLIPASE ACTIVITY 7 64 1.373e-05 0.0001439
444 REGULATION OF PROTEIN ACETYLATION 7 64 1.373e-05 0.0001439
445 REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 6 43 1.388e-05 0.0001445
446 MYELOID LEUKOCYTE MEDIATED IMMUNITY 6 43 1.388e-05 0.0001445
447 REGULATION OF POLYSACCHARIDE METABOLIC PROCESS 6 43 1.388e-05 0.0001445
448 FEMALE SEX DIFFERENTIATION 9 116 1.397e-05 0.0001451
449 REGULATION OF AUTOPHAGY 13 249 1.425e-05 0.0001476
450 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 12 213 1.434e-05 0.0001483
451 NEGATIVE REGULATION OF KINASE ACTIVITY 13 250 1.486e-05 0.0001528
452 WHITE FAT CELL DIFFERENTIATION 4 13 1.487e-05 0.0001528
453 POSITIVE REGULATION OF GLUCONEOGENESIS 4 13 1.487e-05 0.0001528
454 CELLULAR RESPONSE TO RETINOIC ACID 7 65 1.523e-05 0.0001561
455 REGULATION OF TYROSINE PHOSPHORYLATION OF STAT3 PROTEIN 6 44 1.591e-05 0.0001627
456 CARBOHYDRATE DERIVATIVE METABOLIC PROCESS 30 1047 1.598e-05 0.000163
457 MULTI ORGANISM REPRODUCTIVE PROCESS 27 891 1.654e-05 0.0001684
458 LEUKOCYTE ACTIVATION 17 414 1.671e-05 0.0001697
459 ACID SECRETION 7 66 1.686e-05 0.0001705
460 POSITIVE REGULATION OF LIPASE ACTIVITY 7 66 1.686e-05 0.0001705
461 NEGATIVE REGULATION OF CELL PROLIFERATION 22 643 1.713e-05 0.0001729
462 CELLULAR AMINO ACID METABOLIC PROCESS 15 332 1.755e-05 0.0001764
463 EMBRYO DEVELOPMENT 27 894 1.755e-05 0.0001764
464 RESPONSE TO LITHIUM ION 5 27 1.784e-05 0.0001785
465 FLUID TRANSPORT 5 27 1.784e-05 0.0001785
466 PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROCESS 9 120 1.836e-05 0.0001833
467 POSITIVE REGULATION OF DNA METABOLIC PROCESS 11 185 1.986e-05 0.0001979
468 REGULATION OF CELL JUNCTION ASSEMBLY 7 68 2.055e-05 0.0002043
469 POSITIVE REGULATION OF CHOLESTEROL EFFLUX 4 14 2.062e-05 0.0002046
470 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 10 153 2.107e-05 0.0002086
471 CELLULAR RESPONSE TO CYTOKINE STIMULUS 21 606 2.222e-05 0.0002195
472 CARBOHYDRATE TRANSPORT 8 95 2.328e-05 0.0002295
473 NEUROTRANSMITTER TRANSPORT 10 155 2.358e-05 0.0002319
474 REGULATION OF IMMUNE RESPONSE 26 858 2.393e-05 0.0002349
475 MYELOID CELL DIFFERENTIATION 11 189 2.422e-05 0.0002373
476 BONE DEVELOPMENT 10 156 2.492e-05 0.0002436
477 REGULATION OF ANATOMICAL STRUCTURE SIZE 18 472 2.524e-05 0.0002462
478 DICARBOXYLIC ACID TRANSPORT 7 71 2.732e-05 0.0002659
479 CELLULAR RESPONSE TO NITRIC OXIDE 4 15 2.784e-05 0.0002688
480 OXYGEN TRANSPORT 4 15 2.784e-05 0.0002688
481 REGULATION OF NEUROTRANSMITTER UPTAKE 4 15 2.784e-05 0.0002688
482 FRUCTOSE METABOLIC PROCESS 4 15 2.784e-05 0.0002688
483 POSITIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 12 228 2.818e-05 0.0002714
484 REGULATION OF NITRIC OXIDE SYNTHASE ACTIVITY 6 49 2.993e-05 0.0002878
485 NEGATIVE REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 5 30 3.055e-05 0.0002919
486 SODIUM ION HOMEOSTASIS 5 30 3.055e-05 0.0002919
487 HYDROGEN PEROXIDE METABOLIC PROCESS 5 30 3.055e-05 0.0002919
488 REGULATION OF CYTOPLASMIC TRANSPORT 18 481 3.233e-05 0.0003083
489 NEURON DIFFERENTIATION 26 874 3.271e-05 0.0003112
490 ERYTHROCYTE HOMEOSTASIS 7 73 3.277e-05 0.0003112
491 STEROL TRANSPORT 6 50 3.367e-05 0.0003191
492 HEMOSTASIS 14 311 3.487e-05 0.0003298
493 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 7 74 3.582e-05 0.0003374
494 NEGATIVE REGULATION OF HORMONE SECRETION 7 74 3.582e-05 0.0003374
495 REGULATION OF SYNAPTIC VESICLE TRANSPORT 5 31 3.606e-05 0.0003389
496 VASCULAR PROCESS IN CIRCULATORY SYSTEM 10 163 3.632e-05 0.0003408
497 REGULATION OF FATTY ACID BETA OXIDATION 4 16 3.677e-05 0.0003442
498 CELL MATURATION 9 131 3.691e-05 0.0003449
499 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 25 829 3.744e-05 0.0003491
500 POSITIVE REGULATION OF MITOTIC NUCLEAR DIVISION 6 51 3.777e-05 0.0003507
501 RESPONSE TO NICOTINE 6 51 3.777e-05 0.0003507
502 NEGATIVE REGULATION OF SECRETION 11 200 4.075e-05 0.0003777
503 POSITIVE REGULATION OF PURINE NUCLEOTIDE METABOLIC PROCESS 9 133 4.159e-05 0.000384
504 POSITIVE REGULATION OF NUCLEOTIDE METABOLIC PROCESS 9 133 4.159e-05 0.000384
505 REGULATION OF GROWTH 21 633 4.19e-05 0.0003861
506 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER IN RESPONSE TO HYPOXIA 5 32 4.231e-05 0.0003883
507 REGULATION OF LIPID CATABOLIC PROCESS 6 52 4.225e-05 0.0003883
508 POSITIVE REGULATION OF GROWTH 12 238 4.285e-05 0.0003925
509 POSITIVE REGULATION OF PHOSPHOLIPASE ACTIVITY 6 53 4.716e-05 0.0004294
510 POSITIVE REGULATION OF FIBROBLAST PROLIFERATION 6 53 4.716e-05 0.0004294
511 NEGATIVE REGULATION OF CARBOHYDRATE METABOLIC PROCESS 6 53 4.716e-05 0.0004294
512 POSITIVE REGULATION OF NUCLEOTIDE CATABOLIC PROCESS 4 17 4.761e-05 0.0004327
513 RESPONSE TO DEXAMETHASONE 5 33 4.936e-05 0.0004477
514 LOCOMOTION 30 1114 5.067e-05 0.0004587
515 NEURON PROJECTION DEVELOPMENT 19 545 5.089e-05 0.0004597
516 MONOSACCHARIDE TRANSPORT 6 54 5.251e-05 0.0004735
517 REGULATION OF BINDING 13 283 5.403e-05 0.0004863
518 NEUROGENESIS 35 1402 5.433e-05 0.000488
519 TISSUE HOMEOSTASIS 10 171 5.455e-05 0.0004881
520 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 10 171 5.455e-05 0.0004881
521 SKELETAL SYSTEM DEVELOPMENT 17 455 5.475e-05 0.000489
522 RESPONSE TO RETINOIC ACID 8 107 5.498e-05 0.0004901
523 POSITIVE REGULATION OF MAP KINASE ACTIVITY 11 207 5.57e-05 0.0004955
524 PLATELET DERIVED GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 5 34 5.729e-05 0.0005087
525 REGULATION OF ORGANELLE ORGANIZATION 31 1178 5.785e-05 0.0005127
526 NAD METABOLIC PROCESS 6 55 5.834e-05 0.0005161
527 CELLULAR RESPONSE TO MECHANICAL STIMULUS 7 80 5.939e-05 0.0005243
528 REGULATION OF MITOCHONDRIAL FISSION 4 18 6.063e-05 0.0005343
529 REGULATION OF CALCIUM ION TRANSPORT 11 209 6.075e-05 0.0005344
530 VESICLE MEDIATED TRANSPORT 32 1239 6.21e-05 0.0005452
531 METANEPHROS DEVELOPMENT 7 81 6.433e-05 0.0005626
532 REGULATION OF FIBROBLAST PROLIFERATION 7 81 6.433e-05 0.0005626
533 SMAD PROTEIN SIGNAL TRANSDUCTION 6 56 6.467e-05 0.0005646
534 NADH METABOLIC PROCESS 5 35 6.617e-05 0.0005744
535 REGULATION OF DIGESTIVE SYSTEM PROCESS 5 35 6.617e-05 0.0005744
536 RESPONSE TO IRON ION 5 35 6.617e-05 0.0005744
537 LEUKOCYTE DIFFERENTIATION 13 292 7.426e-05 0.0006435
538 RESPONSE TO MUSCLE STRETCH 4 19 7.605e-05 0.0006544
539 NEGATIVE REGULATION OF BLOOD CIRCULATION 5 36 7.607e-05 0.0006544
540 CELLULAR SODIUM ION HOMEOSTASIS 4 19 7.605e-05 0.0006544
541 REGULATION OF OSTEOBLAST DIFFERENTIATION 8 112 7.608e-05 0.0006544
542 CELL CELL SIGNALING 23 767 8.436e-05 0.0007242
543 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 13 296 8.518e-05 0.0007299
544 VASCULOGENESIS 6 59 8.702e-05 0.0007435
545 REGULATION OF PROTEIN AUTOPHOSPHORYLATION 5 37 8.708e-05 0.0007435
546 REGULATION OF DNA METABOLIC PROCESS 14 340 9.09e-05 0.0007746
547 REGULATION OF CHOLESTEROL EFFLUX 4 20 9.414e-05 0.0008008
548 REGULATION OF MYELOID CELL DIFFERENTIATION 10 183 9.621e-05 0.0008169
549 LEUKOCYTE MIGRATION 12 259 9.638e-05 0.0008169
550 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 19 573 9.854e-05 0.0008336
551 REGULATION OF PROTEIN STABILITY 11 221 0.0001001 0.0008454
552 TISSUE REMODELING 7 87 0.0001015 0.0008559
553 REGULATION OF COAGULATION 7 88 0.0001092 0.0009152
554 OVULATION CYCLE PROCESS 7 88 0.0001092 0.0009152
555 NEGATIVE REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 7 88 0.0001092 0.0009152
556 CELLULAR LIPID CATABOLIC PROCESS 9 151 0.0001113 0.0009304
557 CELLULAR RESPONSE TO ABIOTIC STIMULUS 12 263 0.0001114 0.0009304
558 REGULATION OF PROTEIN IMPORT INTO NUCLEUS TRANSLOCATION 4 21 0.0001152 0.0009536
559 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 16 437 0.0001147 0.0009536
560 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 16 437 0.0001147 0.0009536
561 NEGATIVE REGULATION OF SYNAPTIC TRANSMISSION 6 62 0.0001151 0.0009536
562 RESPONSE TO NITRIC OXIDE 4 21 0.0001152 0.0009536
563 REGULATION OF PEPTIDASE ACTIVITY 15 392 0.0001158 0.0009573
564 ALCOHOL METABOLIC PROCESS 14 348 0.0001161 0.000958
565 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 36 1517 0.0001176 0.0009681
566 PURINE CONTAINING COMPOUND METABOLIC PROCESS 15 394 0.0001225 0.001007
567 TRANSCRIPTION INITIATION FROM RNA POLYMERASE II PROMOTER 9 153 0.000123 0.00101
568 CYTOKINE PRODUCTION 8 120 0.0001236 0.001012
569 SEX DIFFERENTIATION 12 266 0.0001239 0.001013
570 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 21 684 0.0001251 0.001021
571 MESONEPHROS DEVELOPMENT 7 90 0.0001258 0.001025
572 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 14 351 0.000127 0.001033
573 POSITIVE REGULATION OF PEPTIDASE ACTIVITY 9 154 0.0001293 0.00105
574 NEURON DEVELOPMENT 21 687 0.0001328 0.001077
575 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 11 229 0.000137 0.001107
576 ALPHA AMINO ACID METABOLIC PROCESS 11 229 0.000137 0.001107
577 REGULATION OF NEUROTRANSMITTER TRANSPORT 6 64 0.0001375 0.001109
578 IN UTERO EMBRYONIC DEVELOPMENT 13 311 0.0001394 0.001117
579 NEGATIVE REGULATION OF HEART CONTRACTION 4 22 0.0001394 0.001117
580 REGULATION OF RESPONSE TO INTERFERON GAMMA 4 22 0.0001394 0.001117
581 HISTONE H3 DEACETYLATION 4 22 0.0001394 0.001117
582 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 9 156 0.0001426 0.00114
583 NEGATIVE REGULATION OF FAT CELL DIFFERENTIATION 5 41 0.0001438 0.001145
584 REGULATION OF ACTIN FILAMENT BASED PROCESS 13 312 0.0001439 0.001145
585 ANION HOMEOSTASIS 5 41 0.0001438 0.001145
586 FOREBRAIN DEVELOPMENT 14 357 0.0001516 0.001203
587 REGULATION OF HEMOPOIESIS 13 314 0.0001533 0.001215
588 CELLULAR AMINO ACID BIOSYNTHETIC PROCESS 7 93 0.0001546 0.001221
589 REGULATION OF DNA BINDING 7 93 0.0001546 0.001221
590 CONNECTIVE TISSUE DEVELOPMENT 10 194 0.0001555 0.001226
591 REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 11 233 0.0001595 0.001256
592 ORGANOPHOSPHATE BIOSYNTHETIC PROCESS 16 450 0.0001604 0.001261
593 NEGATIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 5 42 0.0001616 0.001266
594 POSITIVE REGULATION OF GLUCOSE TRANSPORT 5 42 0.0001616 0.001266
595 REGULATION OF MUSCLE SYSTEM PROCESS 10 195 0.0001622 0.001268
596 REGULATION OF CARDIAC CONDUCTION 6 66 0.0001633 0.001275
597 POSITIVE REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 4 23 0.0001671 0.001303
598 MUSCLE TISSUE DEVELOPMENT 12 275 0.000169 0.001315
599 PHOSPHOLIPID BIOSYNTHETIC PROCESS 11 235 0.0001718 0.001335
600 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 8 126 0.0001733 0.001344
601 TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 7 95 0.0001766 0.001367
602 POSITIVE REGULATION OF PROTEOLYSIS 14 363 0.0001801 0.001392
603 REGULATION OF INSULIN RECEPTOR SIGNALING PATHWAY 5 43 0.0001811 0.001397
604 NEGATIVE REGULATION OF ION TRANSPORT 8 127 0.0001831 0.00141
605 STEROID METABOLIC PROCESS 11 237 0.000185 0.001423
606 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 18 554 0.0001931 0.001481
607 ACTIVATION OF PROTEIN KINASE ACTIVITY 12 279 0.0001931 0.001481
608 REGULATION OF MYELOID CELL APOPTOTIC PROCESS 4 24 0.0001986 0.001515
609 AXON REGENERATION 4 24 0.0001986 0.001515
610 AMMONIUM TRANSMEMBRANE TRANSPORT 4 24 0.0001986 0.001515
611 NEGATIVE REGULATION OF RESPONSE TO CYTOKINE STIMULUS 5 44 0.0002022 0.00154
612 CELLULAR CATABOLIC PROCESS 32 1322 0.0002048 0.001557
613 REGULATION OF ION HOMEOSTASIS 10 201 0.0002074 0.001574
614 ENDOCYTOSIS 17 509 0.0002109 0.001598
615 REGULATION OF PROTEOLYSIS 21 711 0.0002122 0.001606
616 MEMORY 7 98 0.0002143 0.001616
617 MYELOID LEUKOCYTE ACTIVATION 7 98 0.0002143 0.001616
618 REGULATION OF VESICLE MEDIATED TRANSPORT 16 462 0.0002159 0.001626
619 NEGATIVE REGULATION OF CATABOLIC PROCESS 10 203 0.0002246 0.001689
620 REGULATION OF PLASMA LIPOPROTEIN PARTICLE LEVELS 5 45 0.0002252 0.00169
621 POSITIVE REGULATION OF LIPID CATABOLIC PROCESS 4 25 0.0002342 0.001752
622 PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 4 25 0.0002342 0.001752
623 POSITIVE REGULATION OF CELL DIVISION 8 132 0.0002386 0.001782
624 MODIFICATION OF MORPHOLOGY OR PHYSIOLOGY OF OTHER ORGANISM 7 100 0.0002429 0.001811
625 REGULATION OF PROTEIN COMPLEX ASSEMBLY 14 375 0.0002512 0.00187
626 DICARBOXYLIC ACID METABOLIC PROCESS 7 101 0.0002583 0.00192
627 ENERGY RESERVE METABOLIC PROCESS 6 72 0.000264 0.001959
628 REGULATION OF DEVELOPMENTAL GROWTH 12 289 0.0002668 0.001973
629 APOPTOTIC SIGNALING PATHWAY 12 289 0.0002668 0.001973
630 CHOLESTEROL EFFLUX 4 26 0.0002741 0.002024
631 ADULT BEHAVIOR 8 135 0.000278 0.00204
632 ADP METABOLIC PROCESS 5 47 0.0002772 0.00204
633 REGULATION OF GTPASE ACTIVITY 20 673 0.0002776 0.00204
634 PRIMARY ALCOHOL METABOLIC PROCESS 5 47 0.0002772 0.00204
635 COFACTOR METABOLIC PROCESS 13 334 0.0002796 0.002049
636 REGULATION OF PEPTIDE SECRETION 10 209 0.0002837 0.002076
637 ASSOCIATIVE LEARNING 6 73 0.0002847 0.00208
638 MEMBRANE HYPERPOLARIZATION 3 11 0.0002854 0.002081
639 RESPONSE TO ETHANOL 8 136 0.0002923 0.002128
640 OSSIFICATION 11 251 0.0003031 0.002204
641 POSITIVE REGULATION OF PROTEIN SECRETION 10 211 0.0003061 0.002222
642 CIRCADIAN RHYTHM 8 137 0.0003072 0.002223
643 REGULATION OF ACUTE INFLAMMATORY RESPONSE 6 74 0.0003067 0.002223
644 LIPID STORAGE 4 27 0.0003186 0.002299
645 CELLULAR RESPONSE TO DEXAMETHASONE STIMULUS 4 27 0.0003186 0.002299
646 REGULATION OF CELL ADHESION 19 629 0.0003224 0.00232
647 PLACENTA DEVELOPMENT 8 138 0.0003227 0.00232
648 MUSCLE STRUCTURE DEVELOPMENT 15 432 0.00033 0.00237
649 HEXOSE CATABOLIC PROCESS 5 49 0.0003377 0.002418
650 GLOMERULUS DEVELOPMENT 5 49 0.0003377 0.002418
651 REGULATION OF SYNAPTIC PLASTICITY 8 140 0.0003555 0.002541
652 GLUTAMATE SECRETION 4 28 0.0003682 0.002615
653 OXIDOREDUCTION COENZYME METABOLIC PROCESS 7 107 0.0003678 0.002615
654 CELL VOLUME HOMEOSTASIS 4 28 0.0003682 0.002615
655 REGULATION OF SPROUTING ANGIOGENESIS 4 28 0.0003682 0.002615
656 LACTATE TRANSPORT 3 12 0.000377 0.002626
657 REGULATION OF ORGANIC ACID TRANSPORT 5 50 0.0003715 0.002626
658 SODIUM ION EXPORT 3 12 0.000377 0.002626
659 RESPONSE TO PHENYLPROPANOID 3 12 0.000377 0.002626
660 NUCLEOBASE CONTAINING SMALL MOLECULE METABOLIC PROCESS 17 535 0.0003752 0.002626
661 PROTEIN COMPLEX BIOGENESIS 28 1132 0.0003718 0.002626
662 VESICLE FUSION TO PLASMA MEMBRANE 3 12 0.000377 0.002626
663 REGULATION OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR SIGNALING PATHWAY 3 12 0.000377 0.002626
664 BASIC AMINO ACID TRANSPORT 3 12 0.000377 0.002626
665 LACTATE TRANSMEMBRANE TRANSPORT 3 12 0.000377 0.002626
666 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 3 12 0.000377 0.002626
667 SYNAPTIC VESICLE FUSION TO PRESYNAPTIC ACTIVE ZONE MEMBRANE 3 12 0.000377 0.002626
668 PROTEIN COMPLEX ASSEMBLY 28 1132 0.0003718 0.002626
669 IMMUNE EFFECTOR PROCESS 16 486 0.0003786 0.002633
670 REGULATION OF CELLULAR RESPONSE TO STRESS 20 691 0.0003893 0.002704
671 POSITIVE REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 9 179 0.0003969 0.002752
672 CELLULAR RESPIRATION 8 143 0.00041 0.002839
673 RESPONSE TO ISCHEMIA 4 29 0.0004229 0.002903
674 REGULATION OF THE FORCE OF HEART CONTRACTION 4 29 0.0004229 0.002903
675 NEUTRAL LIPID BIOSYNTHETIC PROCESS 4 29 0.0004229 0.002903
676 POTASSIUM ION IMPORT 4 29 0.0004229 0.002903
677 GLUCOSE CATABOLIC PROCESS 4 29 0.0004229 0.002903
678 ACYLGLYCEROL BIOSYNTHETIC PROCESS 4 29 0.0004229 0.002903
679 NEGATIVE REGULATION OF DEFENSE RESPONSE 8 144 0.0004295 0.002943
680 POSITIVE REGULATION OF NEURON DIFFERENTIATION 12 306 0.0004466 0.003047
681 INTERACTION WITH SYMBIONT 5 52 0.0004467 0.003047
682 POSITIVE REGULATION OF INTRINSIC APOPTOTIC SIGNALING PATHWAY 5 52 0.0004467 0.003047
683 NEGATIVE REGULATION OF LIPID METABOLIC PROCESS 6 80 0.0004678 0.003187
684 REGULATION OF VASCULOGENESIS 3 13 0.0004856 0.003247
685 LEUKOCYTE DEGRANULATION 4 30 0.0004833 0.003247
686 REGULATION OF ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE ANTIGEN 3 13 0.0004856 0.003247
687 LIPOPROTEIN TRANSPORT 3 13 0.0004856 0.003247
688 POSITIVE REGULATION OF PROTEIN IMPORT INTO NUCLEUS TRANSLOCATION 3 13 0.0004856 0.003247
689 DICARBOXYLIC ACID BIOSYNTHETIC PROCESS 3 13 0.0004856 0.003247
690 CELLULAR AMINO ACID CATABOLIC PROCESS 7 112 0.0004851 0.003247
691 REGULATION OF ACYL COA BIOSYNTHETIC PROCESS 3 13 0.0004856 0.003247
692 TRANSEPITHELIAL TRANSPORT 3 13 0.0004856 0.003247
693 BROWN FAT CELL DIFFERENTIATION 4 30 0.0004833 0.003247
694 LIPOPROTEIN LOCALIZATION 3 13 0.0004856 0.003247
695 COENZYME METABOLIC PROCESS 11 265 0.0004794 0.003247
696 DIVALENT INORGANIC ANION HOMEOSTASIS 3 13 0.0004856 0.003247
697 POSITIVE REGULATION OF MYELOID CELL DIFFERENTIATION 6 81 0.0005001 0.003339
698 POSITIVE REGULATION OF CELL ACTIVATION 12 311 0.0005158 0.003439
699 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 30 1275 0.0005243 0.00349
700 REGULATION OF INNATE IMMUNE RESPONSE 13 357 0.0005261 0.003497
701 CYTOKINE MEDIATED SIGNALING PATHWAY 15 452 0.0005291 0.003512
702 REGULATION OF MITOCHONDRIAL MEMBRANE POTENTIAL 5 54 0.0005327 0.003531
703 REGULATION OF CELLULAR PROTEIN LOCALIZATION 17 552 0.0005346 0.003538
704 EMBRYONIC ORGAN DEVELOPMENT 14 406 0.0005559 0.003674
705 REGULATION OF NEURON DIFFERENTIATION 17 554 0.0005567 0.003674
706 RESPONSE TO INTERLEUKIN 1 7 115 0.0005687 0.003737
707 NEPHRON DEVELOPMENT 7 115 0.0005687 0.003737
708 RESPONSE TO CALCIUM ION 7 115 0.0005687 0.003737
709 MULTICELLULAR ORGANISM REPRODUCTION 21 768 0.0005867 0.003851
710 PROTEIN COMPLEX SUBUNIT ORGANIZATION 34 1527 0.0005911 0.003874
711 PRESYNAPTIC PROCESS INVOLVED IN SYNAPTIC TRANSMISSION 7 116 0.0005989 0.00392
712 POSITIVE REGULATION OF MITOCHONDRIAL FISSION 3 14 0.0006125 0.003936
713 POSITIVE REGULATION OF MUSCLE CELL DIFFERENTIATION 6 84 0.0006075 0.003936
714 INSULIN LIKE GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 3 14 0.0006125 0.003936
715 RESPONSE TO LOW DENSITY LIPOPROTEIN PARTICLE 3 14 0.0006125 0.003936
716 POSITIVE REGULATION OF SPROUTING ANGIOGENESIS 3 14 0.0006125 0.003936
717 CATECHOLAMINE TRANSPORT 3 14 0.0006125 0.003936
718 STEM CELL DIFFERENTIATION 9 190 0.0006114 0.003936
719 NEGATIVE REGULATION OF GLUCOSE IMPORT 3 14 0.0006125 0.003936
720 REGULATION OF CAMP DEPENDENT PROTEIN KINASE ACTIVITY 3 14 0.0006125 0.003936
721 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 9 190 0.0006114 0.003936
722 RESPONSE TO LAMINAR FLUID SHEAR STRESS 3 14 0.0006125 0.003936
723 REGULATION OF SMOOTH MUSCLE CELL APOPTOTIC PROCESS 3 14 0.0006125 0.003936
724 ANTIGEN PROCESSING AND PRESENTATION OF ENDOGENOUS PEPTIDE ANTIGEN 3 14 0.0006125 0.003936
725 REGULATION OF MUSCLE CELL DIFFERENTIATION 8 152 0.000615 0.003947
726 SINGLE ORGANISM CELL ADHESION 15 459 0.0006196 0.00397
727 METANEPHRIC NEPHRON DEVELOPMENT 4 32 0.000622 0.00397
728 BLOOD VESSEL REMODELING 4 32 0.000622 0.00397
729 REGULATION OF ACTIN CYTOSKELETON REORGANIZATION 4 32 0.000622 0.00397
730 RECEPTOR MEDIATED ENDOCYTOSIS 10 231 0.0006232 0.003972
731 REGULATION OF CYTOKINE PRODUCTION 17 563 0.0006663 0.004241
732 POTASSIUM ION TRANSPORT 8 154 0.0006703 0.004261
733 POSITIVE REGULATION OF DNA REPLICATION 6 86 0.0006884 0.00437
734 MUSCLE ORGAN DEVELOPMENT 11 277 0.0006923 0.004387
735 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 16 514 0.000693 0.004387
736 POSITIVE REGULATION OF RESPONSE TO CYTOKINE STIMULUS 4 33 0.000701 0.004432
737 NEGATIVE REGULATION OF CELLULAR CATABOLIC PROCESS 8 156 0.0007294 0.004605
738 VITAMIN METABOLIC PROCESS 7 120 0.000733 0.004622
739 POSITIVE REGULATION OF ION TRANSPORT 10 236 0.000735 0.004628
740 ANTIGEN PROCESSING AND PRESENTATION VIA MHC CLASS IB 3 15 0.0007586 0.004713
741 INTERLEUKIN 1 PRODUCTION 3 15 0.0007586 0.004713
742 NEGATIVE REGULATION OF HISTONE ACETYLATION 3 15 0.0007586 0.004713
743 CELLULAR MONOVALENT INORGANIC ANION HOMEOSTASIS 3 15 0.0007586 0.004713
744 LONG TERM SYNAPTIC DEPRESSION 3 15 0.0007586 0.004713
745 CELLULAR ANION HOMEOSTASIS 3 15 0.0007586 0.004713
746 RESPONSE TO VITAMIN E 3 15 0.0007586 0.004713
747 REGULATION OF HYDROGEN PEROXIDE METABOLIC PROCESS 3 15 0.0007586 0.004713
748 RESPONSE TO HYDROPEROXIDE 3 15 0.0007586 0.004713
749 RESPONSE TO MERCURY ION 3 15 0.0007586 0.004713
750 WATER SOLUBLE VITAMIN METABOLIC PROCESS 6 88 0.0007774 0.004823
751 REGULATION OF TRIGLYCERIDE METABOLIC PROCESS 4 34 0.0007869 0.004869
752 RENAL WATER HOMEOSTASIS 4 34 0.0007869 0.004869
753 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 9 197 0.0007916 0.004892
754 REGULATION OF EPITHELIAL CELL APOPTOTIC PROCESS 5 59 0.0008022 0.004931
755 MONOSACCHARIDE CATABOLIC PROCESS 5 59 0.0008022 0.004931
756 MUSCLE SYSTEM PROCESS 11 282 0.0008018 0.004931
757 REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 5 59 0.0008022 0.004931
758 POSITIVE REGULATION OF CELL ADHESION 13 376 0.00085 0.005213
759 REGULATION OF ENDOCYTOSIS 9 199 0.0008504 0.005213
760 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 5 60 0.0008665 0.005305
761 SODIUM ION TRANSMEMBRANE TRANSPORT 6 90 0.0008751 0.005344
762 REGULATION OF CELL MATRIX ADHESION 6 90 0.0008751 0.005344
763 REGULATION OF GASTRULATION 4 35 0.0008799 0.005345
764 NEURON APOPTOTIC PROCESS 4 35 0.0008799 0.005345
765 REGULATION OF FATTY ACID BIOSYNTHETIC PROCESS 4 35 0.0008799 0.005345
766 RESPONSE TO MONOAMINE 4 35 0.0008799 0.005345
767 REGULATION OF TRANSMEMBRANE TRANSPORT 14 426 0.0008866 0.005379
768 CARDIAC MYOFIBRIL ASSEMBLY 3 16 0.0009252 0.005562
769 NEGATIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION 3 16 0.0009252 0.005562
770 POSITIVE REGULATION OF ANTIGEN PROCESSING AND PRESENTATION 3 16 0.0009252 0.005562
771 POSITIVE REGULATION OF NEUROTRANSMITTER TRANSPORT 3 16 0.0009252 0.005562
772 RESPONSE TO EPINEPHRINE 3 16 0.0009252 0.005562
773 MONOCYTE DIFFERENTIATION 3 16 0.0009252 0.005562
774 GLYCOSIDE METABOLIC PROCESS 3 16 0.0009252 0.005562
775 DNA TEMPLATED TRANSCRIPTION INITIATION 9 202 0.0009451 0.005674
776 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 13 381 0.0009587 0.005749
777 POSITIVE REGULATION OF HEMOPOIESIS 8 163 0.0009706 0.005812
778 REGULATION OF WOUND HEALING 7 126 0.0009776 0.005846
779 NEGATIVE REGULATION OF PROTEIN KINASE B SIGNALING 4 36 0.0009803 0.005848
780 REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 4 36 0.0009803 0.005848
781 REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 6 92 0.000982 0.00585
782 CELL SUBSTRATE ADHESION 8 164 0.00101 0.006008
783 POSITIVE REGULATION OF BINDING 7 127 0.001024 0.006085
784 LIPID CATABOLIC PROCESS 10 247 0.00104 0.006171
785 INORGANIC ANION TRANSPORT 7 128 0.001072 0.006338
786 REGULATION OF LIPID BIOSYNTHETIC PROCESS 7 128 0.001072 0.006338
787 PROTEIN HOMOOLIGOMERIZATION 10 248 0.001072 0.006338
788 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 20 750 0.001074 0.006339
789 REGULATION OF MUSCLE ADAPTATION 5 63 0.001082 0.006374
790 RESPONSE TO OSMOTIC STRESS 5 63 0.001082 0.006374
791 GLYCEROLIPID CATABOLIC PROCESS 4 37 0.001089 0.006404
792 ELECTRON TRANSPORT CHAIN 6 94 0.001099 0.006454
793 CELLULAR RESPONSE TO LITHIUM ION 3 17 0.001113 0.006475
794 HEXOSE TRANSMEMBRANE TRANSPORT 3 17 0.001113 0.006475
795 REGULATION OF ENERGY HOMEOSTASIS 3 17 0.001113 0.006475
796 NEGATIVE REGULATION OF ANOIKIS 3 17 0.001113 0.006475
797 GLUCOSE TRANSMEMBRANE TRANSPORT 3 17 0.001113 0.006475
798 NEGATIVE REGULATION OF GLUCOSE TRANSPORT 3 17 0.001113 0.006475
799 REGULATION OF PRI MIRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 3 17 0.001113 0.006475
800 ANTIGEN PROCESSING AND PRESENTATION OF ENDOGENOUS ANTIGEN 3 17 0.001113 0.006475
801 ALPHA AMINO ACID CATABOLIC PROCESS 6 95 0.001161 0.006743
802 RIBONUCLEOSIDE DIPHOSPHATE METABOLIC PROCESS 5 64 0.001162 0.006743
803 IMMUNE RESPONSE 26 1100 0.001172 0.00679
804 LYMPHOCYTE ACTIVATION 12 342 0.001178 0.006817
805 NEGATIVE REGULATION OF INNATE IMMUNE RESPONSE 4 38 0.001205 0.006956
806 REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 4 38 0.001205 0.006956
807 ORGANONITROGEN COMPOUND CATABOLIC PROCESS 12 343 0.001208 0.006962
808 MYELOID LEUKOCYTE DIFFERENTIATION 6 96 0.001226 0.007039
809 PROTEIN STABILIZATION 7 131 0.001227 0.007039
810 FEMALE GAMETE GENERATION 6 96 0.001226 0.007039
811 MONOCARBOXYLIC ACID CATABOLIC PROCESS 6 96 0.001226 0.007039
812 GLUTAMINE FAMILY AMINO ACID METABOLIC PROCESS 5 65 0.001247 0.007117
813 REGULATION OF CHEMOKINE PRODUCTION 5 65 0.001247 0.007117
814 REGULATION OF RESPONSE TO OXIDATIVE STRESS 5 65 0.001247 0.007117
815 PYRUVATE METABOLIC PROCESS 5 65 0.001247 0.007117
816 GLAND MORPHOGENESIS 6 97 0.001293 0.007374
817 REGULATION OF RESPONSE TO EXTRACELLULAR STIMULUS 8 171 0.00132 0.007437
818 CELLULAR MODIFIED AMINO ACID CATABOLIC PROCESS 3 18 0.001324 0.007437
819 ATP GENERATION FROM ADP 4 39 0.00133 0.007437
820 NEGATIVE REGULATION OF ENDOCYTOSIS 4 39 0.00133 0.007437
821 POTASSIUM ION HOMEOSTASIS 3 18 0.001324 0.007437
822 MODULATION BY HOST OF VIRAL PROCESS 3 18 0.001324 0.007437
823 ORGAN MATURATION 3 18 0.001324 0.007437
824 ANATOMICAL STRUCTURE MATURATION 4 39 0.00133 0.007437
825 POLYOL TRANSPORT 3 18 0.001324 0.007437
826 OVULATION 3 18 0.001324 0.007437
827 REGULATION OF RESPONSE TO NUTRIENT LEVELS 8 171 0.00132 0.007437
828 MAST CELL MEDIATED IMMUNITY 3 18 0.001324 0.007437
829 EPITHELIAL CELL DIFFERENTIATION 15 495 0.001322 0.007437
830 PLATELET AGGREGATION 4 39 0.00133 0.007437
831 SPLEEN DEVELOPMENT 4 39 0.00133 0.007437
832 NEGATIVE REGULATION OF MITOCHONDRION ORGANIZATION 4 39 0.00133 0.007437
833 REGULATION OF VASOCONSTRICTION 5 66 0.001335 0.007459
834 REGULATION OF PEPTIDE TRANSPORT 10 256 0.00136 0.007588
835 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 6 98 0.001363 0.007589
836 RESPONSE TO VITAMIN 6 98 0.001363 0.007589
837 REGULATION OF CELL SIZE 8 172 0.00137 0.007617
838 SIGNAL RELEASE 8 173 0.001422 0.007893
839 NEGATIVE REGULATION OF CELL DEVELOPMENT 11 303 0.00143 0.007931
840 CHLORIDE TRANSPORT 6 99 0.001437 0.007958
841 POSITIVE REGULATION OF CELL MATRIX ADHESION 4 40 0.001463 0.008097
842 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 9 216 0.001507 0.00833
843 NEGATIVE REGULATION OF INFLAMMATORY RESPONSE 6 100 0.001513 0.008351
844 REGULATION OF CYTOSKELETON ORGANIZATION 15 502 0.001518 0.008366
845 POSITIVE REGULATION OF LEUKOCYTE PROLIFERATION 7 136 0.001523 0.008388
846 CELLULAR RESPONSE TO FLUID SHEAR STRESS 3 19 0.001558 0.008477
847 KIDNEY VASCULATURE DEVELOPMENT 3 19 0.001558 0.008477
848 NEGATIVE REGULATION OF NUCLEOSIDE METABOLIC PROCESS 3 19 0.001558 0.008477
849 REGULATION OF NITRIC OXIDE SYNTHASE BIOSYNTHETIC PROCESS 3 19 0.001558 0.008477
850 POSITIVE REGULATION OF TOLL LIKE RECEPTOR SIGNALING PATHWAY 3 19 0.001558 0.008477
851 REGULATION OF CELL MIGRATION INVOLVED IN SPROUTING ANGIOGENESIS 3 19 0.001558 0.008477
852 NEGATIVE REGULATION OF ATP METABOLIC PROCESS 3 19 0.001558 0.008477
853 MONOVALENT INORGANIC ANION HOMEOSTASIS 3 19 0.001558 0.008477
854 RENAL SYSTEM VASCULATURE DEVELOPMENT 3 19 0.001558 0.008477
855 MACROPHAGE DIFFERENTIATION 3 19 0.001558 0.008477
856 REGULATION OF PROTEIN TARGETING 11 307 0.001587 0.008625
857 REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION 6 101 0.001592 0.008645
858 NEGATIVE REGULATION OF STRESS ACTIVATED MAPK CASCADE 4 41 0.001606 0.00868
859 NEGATIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 4 41 0.001606 0.00868
860 CELLULAR RESPONSE TO ESTROGEN STIMULUS 4 41 0.001606 0.00868
861 MYELOID CELL ACTIVATION INVOLVED IN IMMUNE RESPONSE 4 41 0.001606 0.00868
862 NEGATIVE REGULATION OF OSSIFICATION 5 69 0.00163 0.008788
863 IRON ION HOMEOSTASIS 5 69 0.00163 0.008788
864 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 13 406 0.001693 0.00912
865 CATECHOLAMINE METABOLIC PROCESS 4 42 0.001758 0.009424
866 POSITIVE REGULATION OF DNA BINDING 4 42 0.001758 0.009424
867 REGULATION OF CIRCADIAN RHYTHM 6 103 0.00176 0.009424
868 DETECTION OF MECHANICAL STIMULUS 4 42 0.001758 0.009424
869 CATECHOL CONTAINING COMPOUND METABOLIC PROCESS 4 42 0.001758 0.009424
870 REGULATION OF NEURON PROJECTION DEVELOPMENT 13 408 0.001768 0.009457
871 EMBRYONIC HEMOPOIESIS 3 20 0.001816 0.009559
872 GLUTAMINE FAMILY AMINO ACID BIOSYNTHETIC PROCESS 3 20 0.001816 0.009559
873 WATER TRANSPORT 3 20 0.001816 0.009559
874 ALDITOL METABOLIC PROCESS 3 20 0.001816 0.009559
875 MIDDLE EAR MORPHOGENESIS 3 20 0.001816 0.009559
876 PROTEIN ADP RIBOSYLATION 3 20 0.001816 0.009559
877 RESPONSE TO VITAMIN A 3 20 0.001816 0.009559
878 REGULATION OF NEURON PROJECTION REGENERATION 3 20 0.001816 0.009559
879 RESPONSE TO LIPOPROTEIN PARTICLE 3 20 0.001816 0.009559
880 INTRACELLULAR LIPID TRANSPORT 3 20 0.001816 0.009559
881 POSITIVE REGULATION OF LIPID STORAGE 3 20 0.001816 0.009559
882 REGULATION OF SULFUR METABOLIC PROCESS 3 20 0.001816 0.009559
883 MELANOCYTE DIFFERENTIATION 3 20 0.001816 0.009559
884 RESPONSE TO LEPTIN 3 20 0.001816 0.009559
885 INTRACELLULAR STEROID HORMONE RECEPTOR SIGNALING PATHWAY 5 71 0.001851 0.009699
886 CELLULAR HORMONE METABOLIC PROCESS 6 104 0.001849 0.009699
887 GROWTH 13 410 0.001846 0.009699
888 BODY FLUID SECRETION 5 71 0.001851 0.009699
889 INNATE IMMUNE RESPONSE 17 619 0.001854 0.009703
890 CELL PROJECTION ORGANIZATION 22 902 0.001905 0.009962
NumGOOverlapSizeP ValueAdj. P Value
1 ACTIVE TRANSMEMBRANE TRANSPORTER ACTIVITY 42 356 6.268e-29 5.823e-26
2 TRANSMEMBRANE TRANSPORTER ACTIVITY 55 997 2.749e-21 1.277e-18
3 TRANSPORTER ACTIVITY 61 1276 1.671e-20 5.176e-18
4 SECONDARY ACTIVE TRANSMEMBRANE TRANSPORTER ACTIVITY 26 233 1.407e-17 3.269e-15
5 ENZYME BINDING 64 1737 7.579e-16 1.408e-13
6 ANION TRANSMEMBRANE TRANSPORTER ACTIVITY 26 293 3.866e-15 5.987e-13
7 KINASE BINDING 34 606 1.591e-13 2.111e-11
8 ADENYL NUCLEOTIDE BINDING 55 1514 2.453e-13 2.849e-11
9 IDENTICAL PROTEIN BINDING 48 1209 4.677e-13 4.828e-11
10 ATPASE ACTIVITY COUPLED TO MOVEMENT OF SUBSTANCES 16 121 2.034e-12 1.796e-10
11 ORGANIC ACID TRANSMEMBRANE TRANSPORTER ACTIVITY 17 142 2.126e-12 1.796e-10
12 ACTIVE ION TRANSMEMBRANE TRANSPORTER ACTIVITY 18 171 4.331e-12 3.353e-10
13 ORGANIC ANION TRANSMEMBRANE TRANSPORTER ACTIVITY 18 178 8.576e-12 5.691e-10
14 RIBONUCLEOTIDE BINDING 59 1860 8.266e-12 5.691e-10
15 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 12 64 1.793e-11 1.111e-09
16 SYMPORTER ACTIVITY 16 142 2.453e-11 1.424e-09
17 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 12 81 3.209e-10 1.754e-08
18 PROTEIN TYROSINE KINASE ACTIVITY 16 176 6.246e-10 3.224e-08
19 STEROID BINDING 12 91 1.284e-09 6.277e-08
20 ALDEHYDE DEHYDROGENASE NAD ACTIVITY 7 19 1.787e-09 8.302e-08
21 TRANSCRIPTION FACTOR BINDING 26 524 1.934e-09 8.556e-08
22 CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 28 622 3.844e-09 1.623e-07
23 KINASE ACTIVITY 33 842 4.51e-09 1.821e-07
24 PROTEIN DIMERIZATION ACTIVITY 39 1149 8.642e-09 3.345e-07
25 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 10 70 1.426e-08 5.297e-07
26 ANTIPORTER ACTIVITY 10 74 2.472e-08 8.834e-07
27 COFACTOR BINDING 17 263 3.208e-08 1.104e-06
28 RECEPTOR BINDING 44 1476 4.012e-08 1.323e-06
29 GROWTH FACTOR BINDING 12 123 4.131e-08 1.323e-06
30 METAL ION TRANSMEMBRANE TRANSPORTER ACTIVITY 21 417 5.842e-08 1.809e-06
31 PHOSPHATIDYLINOSITOL 3 KINASE BINDING 7 30 6.431e-08 1.927e-06
32 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 34 992 6.957e-08 2.02e-06
33 OXIDOREDUCTASE ACTIVITY ACTING ON THE ALDEHYDE OR OXO GROUP OF DONORS 8 46 8.409e-08 2.367e-06
34 DRUG TRANSPORTER ACTIVITY 6 21 1.551e-07 4.239e-06
35 INORGANIC CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 23 527 1.787e-07 4.744e-06
36 LIPID BINDING 26 657 1.852e-07 4.779e-06
37 OXIDOREDUCTASE ACTIVITY ACTING ON THE ALDEHYDE OR OXO GROUP OF DONORS NAD OR NADP AS ACCEPTOR 7 36 2.476e-07 6.216e-06
38 PROTEIN DOMAIN SPECIFIC BINDING 25 624 2.572e-07 6.288e-06
39 ANION CATION SYMPORTER ACTIVITY 8 53 2.651e-07 6.315e-06
40 PROTEIN HOMODIMERIZATION ACTIVITY 27 722 3.258e-07 7.567e-06
41 ATPASE ACTIVITY COUPLED 17 313 3.898e-07 8.832e-06
42 SOLUTE CATION SYMPORTER ACTIVITY 10 99 4.094e-07 9.055e-06
43 AMINO ACID TRANSMEMBRANE TRANSPORTER ACTIVITY 9 79 5.604e-07 1.211e-05
44 MONOVALENT INORGANIC CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 18 366 7.518e-07 1.552e-05
45 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 17 328 7.482e-07 1.552e-05
46 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 14 226 9.004e-07 1.819e-05
47 SODIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 11 136 1.022e-06 2.02e-05
48 HORMONE BINDING 8 65 1.329e-06 2.572e-05
49 PROTEIN KINASE ACTIVITY 24 640 1.458e-06 2.765e-05
50 MOLECULAR FUNCTION REGULATOR 38 1353 1.672e-06 3.107e-05
51 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 16 315 2.073e-06 3.776e-05
52 ORGANIC ACID BINDING 13 209 2.123e-06 3.793e-05
53 PROTEIN PHOSPHATASE BINDING 10 120 2.432e-06 4.263e-05
54 OXIDOREDUCTASE ACTIVITY 25 719 3.359e-06 5.779e-05
55 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 23 629 3.711e-06 6.268e-05
56 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II ACTIVATING TRANSCRIPTION FACTOR BINDING 7 53 3.824e-06 6.343e-05
57 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 22 588 4.229e-06 6.893e-05
58 L AMINO ACID TRANSMEMBRANE TRANSPORTER ACTIVITY 7 54 4.347e-06 6.963e-05
59 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 13 228 5.527e-06 8.702e-05
60 PHOSPHATASE BINDING 11 162 5.657e-06 8.759e-05
61 IRON ION BINDING 11 163 6.001e-06 9.14e-05
62 STEROID HORMONE RECEPTOR ACTIVITY 7 59 7.946e-06 0.0001191
63 MACROMOLECULAR COMPLEX BINDING 37 1399 9.193e-06 0.0001356
64 OXIDOREDUCTASE ACTIVITY ACTING ON PEROXIDE AS ACCEPTOR 6 42 1.207e-05 0.0001752
65 X1 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 6 43 1.388e-05 0.0001984
66 CARBOHYDRATE TRANSPORTER ACTIVITY 6 44 1.591e-05 0.000224
67 OXYGEN TRANSPORTER ACTIVITY 4 14 2.062e-05 0.0002859
68 OXYGEN BINDING 6 47 2.346e-05 0.0003206
69 ANTIOXIDANT ACTIVITY 7 70 2.488e-05 0.0003302
70 ATPASE ACTIVITY 17 427 2.476e-05 0.0003302
71 INSULIN LIKE GROWTH FACTOR RECEPTOR BINDING 4 15 2.784e-05 0.0003643
72 REGULATORY REGION NUCLEIC ACID BINDING 25 818 3.01e-05 0.0003883
73 SNARE BINDING 9 128 3.073e-05 0.0003911
74 FATTY ACID BINDING 5 31 3.606e-05 0.0004527
75 PHOSPHATIDYLINOSITOL KINASE ACTIVITY 6 51 3.777e-05 0.0004678
76 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 9 133 4.159e-05 0.0005084
77 INSULIN RECEPTOR BINDING 5 32 4.231e-05 0.0005104
78 TETRAPYRROLE BINDING 9 134 4.411e-05 0.0005254
79 HISTONE DEACETYLASE BINDING 8 105 4.804e-05 0.0005579
80 NAD DEPENDENT PROTEIN DEACETYLASE ACTIVITY 4 17 4.761e-05 0.0005579
81 DICARBOXYLIC ACID TRANSMEMBRANE TRANSPORTER ACTIVITY 5 33 4.936e-05 0.0005661
82 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 31 1199 8.009e-05 0.0008964
83 COENZYME BINDING 10 179 8.005e-05 0.0008964
84 SEQUENCE SPECIFIC DNA BINDING 28 1037 8.773e-05 0.0009702
85 MONOSACCHARIDE TRANSMEMBRANE TRANSPORTER ACTIVITY 4 20 9.414e-05 0.001019
86 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 7 86 9.435e-05 0.001019
87 ORGANIC HYDROXY COMPOUND TRANSMEMBRANE TRANSPORTER ACTIVITY 6 60 9.57e-05 0.001022
88 SNAP RECEPTOR ACTIVITY 5 38 9.927e-05 0.001048
89 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 13 303 0.0001076 0.001124
90 FERROUS IRON BINDING 4 22 0.0001394 0.001439
91 MONOCARBOXYLIC ACID BINDING 6 65 0.00015 0.001531
92 SYNTAXIN BINDING 7 93 0.0001546 0.001561
93 TRANSCRIPTION COFACTOR BINDING 4 24 0.0001986 0.001963
94 EPHRIN RECEPTOR BINDING 4 24 0.0001986 0.001963
95 GROWTH FACTOR RECEPTOR BINDING 8 129 0.0002038 0.001993
96 MONOCARBOXYLIC ACID TRANSMEMBRANE TRANSPORTER ACTIVITY 5 45 0.0002252 0.00218
97 TRANSITION METAL ION BINDING 33 1400 0.0002626 0.002515
98 ION ANTIPORTER ACTIVITY 5 47 0.0002772 0.002625
99 LACTATE TRANSMEMBRANE TRANSPORTER ACTIVITY 3 11 0.0002854 0.002625
100 TRANSCRIPTION COACTIVATOR BINDING 3 11 0.0002854 0.002625
101 ANION TRANSMEMBRANE TRANSPORTING ATPASE ACTIVITY 3 11 0.0002854 0.002625
102 TRANSCRIPTION FACTOR ACTIVITY DIRECT LIGAND REGULATED SEQUENCE SPECIFIC DNA BINDING 5 48 0.0003063 0.00279
103 TRANSCRIPTION COACTIVATOR ACTIVITY 12 296 0.0003314 0.002989
104 ATPASE BINDING 6 76 0.0003546 0.00314
105 CHROMATIN BINDING 15 435 0.0003549 0.00314
106 SIGNAL TRANSDUCER ACTIVITY 38 1731 0.0003606 0.00316
107 HISTONE ACETYLTRANSFERASE BINDING 4 28 0.0003682 0.003196
108 HISTONE DEACETYLASE ACTIVITY H3 K14 SPECIFIC 3 12 0.000377 0.003243
109 SOLUTE SODIUM SYMPORTER ACTIVITY 5 51 0.0004078 0.003475
110 ORGANIC ACID SODIUM SYMPORTER ACTIVITY 4 30 0.0004833 0.004082
111 DOUBLE STRANDED DNA BINDING 21 764 0.0005486 0.004591
112 DEACETYLASE ACTIVITY 5 55 0.0005802 0.004812
113 SUGAR TRANSMEMBRANE TRANSPORTER ACTIVITY 4 32 0.000622 0.005114
114 ACTIVATING TRANSCRIPTION FACTOR BINDING 5 57 0.0006845 0.005578
115 PROTEIN HETERODIMERIZATION ACTIVITY 15 468 0.0007552 0.005922
116 WATER TRANSMEMBRANE TRANSPORTER ACTIVITY 3 15 0.0007586 0.005922
117 POLYOL TRANSMEMBRANE TRANSPORTER ACTIVITY 3 15 0.0007586 0.005922
118 CORE PROMOTER PROXIMAL REGION DNA BINDING 13 371 0.0007517 0.005922
119 PLATELET DERIVED GROWTH FACTOR RECEPTOR BINDING 3 15 0.0007586 0.005922
120 MITOGEN ACTIVATED PROTEIN KINASE KINASE BINDING 3 16 0.0009252 0.007163
121 RNA POLYMERASE II TRANSCRIPTION COACTIVATOR ACTIVITY 4 36 0.0009803 0.007527
122 SIGNALING RECEPTOR ACTIVITY 31 1393 0.001056 0.008039
123 PEPTIDE HORMONE RECEPTOR BINDING 3 17 0.001113 0.008408
124 INORGANIC ANION TRANSMEMBRANE TRANSPORTER ACTIVITY 7 130 0.001173 0.008791
125 SYNTAXIN 1 BINDING 3 18 0.001324 0.009838
NumGOOverlapSizeP ValueAdj. P Value
1 INTRINSIC COMPONENT OF PLASMA MEMBRANE 63 1649 2.431e-16 1.42e-13
2 MEMBRANE REGION 47 1134 1.829e-13 5.342e-11
3 PLASMA MEMBRANE REGION 40 929 4.685e-12 9.121e-10
4 BASOLATERAL PLASMA MEMBRANE 19 211 1.738e-11 2.537e-09
5 MEMBRANE MICRODOMAIN 21 288 7.968e-11 9.306e-09
6 APICAL PLASMA MEMBRANE 20 292 6.886e-10 6.702e-08
7 INTRACELLULAR VESICLE 41 1259 1.102e-08 9.19e-07
8 SECRETORY VESICLE 23 461 1.578e-08 1.152e-06
9 APICAL PART OF CELL 20 361 2.564e-08 1.664e-06
10 MITOCHONDRION 47 1633 3.697e-08 2.159e-06
11 SECRETORY GRANULE 19 352 8.724e-08 4.632e-06
12 BASAL PLASMA MEMBRANE 7 33 1.308e-07 6.364e-06
13 BASAL PART OF CELL 8 51 1.946e-07 8.741e-06
14 PLATELET ALPHA GRANULE 9 75 3.57e-07 1.489e-05
15 VESICLE LUMEN 10 106 7.761e-07 3.022e-05
16 SYNAPSE PART 23 610 2.228e-06 8.131e-05
17 EXTRACELLULAR SPACE 38 1376 2.497e-06 8.579e-05
18 CELL SURFACE 26 757 2.644e-06 8.579e-05
19 VACUOLE 34 1180 3.64e-06 0.0001119
20 CYTOPLASMIC VESICLE PART 22 601 5.986e-06 0.0001748
21 SYNAPSE 25 754 7.665e-06 0.0002132
22 PLASMA MEMBRANE RAFT 8 86 1.118e-05 0.0002968
23 NEURON PART 34 1265 1.589e-05 0.0004033
24 PERINUCLEAR REGION OF CYTOPLASM 22 642 1.673e-05 0.000407
25 SARCOLEMMA 9 125 2.545e-05 0.0005946
26 GLIAL CELL PROJECTION 4 15 2.784e-05 0.0006254
27 ENDOCYTIC VESICLE LUMEN 4 17 4.761e-05 0.00103
28 MITOCHONDRIAL PART 27 953 5.295e-05 0.001104
29 NEURON PROJECTION 26 942 0.0001119 0.002242
30 MAST CELL GRANULE 4 21 0.0001152 0.002242
31 CELL PROJECTION 40 1786 0.0001633 0.003076
32 NUCLEAR EUCHROMATIN 4 24 0.0001986 0.003625
33 POSTSYNAPSE 14 378 0.0002724 0.004821
34 LYTIC VACUOLE 17 526 0.0003089 0.005305
35 TRANSCRIPTION FACTOR COMPLEX 12 298 0.0003522 0.005877
36 HEMOGLOBIN COMPLEX 3 12 0.000377 0.006116
37 BLOOD MICROPARTICLE 8 143 0.00041 0.006139
38 SECRETORY GRANULE MEMBRANE 6 78 0.0004082 0.006139
39 MITOCHONDRIAL ENVELOPE 20 691 0.0003893 0.006139
40 PLATELET ALPHA GRANULE MEMBRANE 3 13 0.0004856 0.006789
41 SNARE COMPLEX 5 53 0.0004883 0.006789
42 CELL JUNCTION 28 1151 0.0004838 0.006789
43 EUCHROMATIN 4 31 0.0005496 0.007464
44 PLATELET ALPHA GRANULE LUMEN 5 55 0.0005802 0.007701
45 OUTER MEMBRANE 9 190 0.0006114 0.007934
46 SECRETORY GRANULE LUMEN 6 85 0.000647 0.008214
47 APICAL DENDRITE 3 15 0.0007586 0.009426

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 ABC_transporters_hsa02010 14 45 1.575e-16 8.192e-15
2 AMPK_signaling_pathway_hsa04152 17 121 1.469e-13 3.819e-12
3 PI3K_Akt_signaling_pathway_hsa04151 25 352 2.055e-12 3.562e-11
4 HIF_1_signaling_pathway_hsa04066 14 100 2.286e-11 2.972e-10
5 FoxO_signaling_pathway_hsa04068 14 132 9.983e-10 1.038e-08
6 MAPK_signaling_pathway_hsa04010 19 295 5.149e-09 4.462e-08
7 Focal_adhesion_hsa04510 15 199 2.792e-08 2.074e-07
8 cGMP_PKG_signaling_pathway_hsa04022 13 163 1.24e-07 8.058e-07
9 Rap1_signaling_pathway_hsa04015 14 206 2.939e-07 1.698e-06
10 Ras_signaling_pathway_hsa04014 13 232 6.674e-06 3.471e-05
11 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 10 139 9.097e-06 4.3e-05
12 Jak_STAT_signaling_pathway_hsa04630 10 162 3.446e-05 0.0001493
13 Apelin_signaling_pathway_hsa04371 9 137 5.246e-05 0.0002099
14 Phospholipase_D_signaling_pathway_hsa04072 9 146 8.594e-05 0.0003192
15 Cytokine_cytokine_receptor_interaction_hsa04060 12 270 0.0001425 0.0004939
16 Necroptosis_hsa04217 9 164 0.0002078 0.0006753
17 Apoptosis_hsa04210 8 138 0.0003227 0.000987
18 mTOR_signaling_pathway_hsa04150 8 151 0.0005888 0.001701
19 Autophagy_animal_hsa04140 7 128 0.001072 0.002934
20 TNF_signaling_pathway_hsa04668 6 108 0.002239 0.00582
21 Mitophagy_animal_hsa04137 4 65 0.008531 0.02113
22 p53_signaling_pathway_hsa04115 4 68 0.009973 0.02357
23 cAMP_signaling_pathway_hsa04024 7 198 0.01172 0.02628
24 Adherens_junction_hsa04520 4 72 0.01213 0.02628
25 Ferroptosis_hsa04216 3 40 0.01313 0.02732
26 Cellular_senescence_hsa04218 6 160 0.01466 0.02931
27 Sphingolipid_signaling_pathway_hsa04071 5 118 0.01563 0.0301
28 Oocyte_meiosis_hsa04114 5 124 0.01897 0.03522
29 Gap_junction_hsa04540 4 88 0.02362 0.04236
30 Calcium_signaling_pathway_hsa04020 6 182 0.02577 0.04466
31 VEGF_signaling_pathway_hsa04370 3 59 0.03647 0.06117
32 Peroxisome_hsa04146 3 83 0.08343 0.1348
33 TGF_beta_signaling_pathway_hsa04350 3 84 0.08577 0.1348
34 ErbB_signaling_pathway_hsa04012 3 85 0.08814 0.1348
35 Regulation_of_actin_cytoskeleton_hsa04810 5 208 0.1159 0.1722
36 Phosphatidylinositol_signaling_system_hsa04070 3 99 0.124 0.1791
37 ECM_receptor_interaction_hsa04512 2 82 0.2689 0.378
38 Phagosome_hsa04145 3 152 0.2898 0.3965
39 Tight_junction_hsa04530 3 170 0.3505 0.4445
40 Neuroactive_ligand_receptor_interaction_hsa04080 4 278 0.4501 0.5202
41 Lysosome_hsa04142 2 123 0.4501 0.5202
42 Cell_adhesion_molecules_.CAMs._hsa04514 2 145 0.5367 0.6067
43 Endocytosis_hsa04144 2 244 0.8065 0.8737

Quest ID: 3eb46da0a0c089356c1e64217b80f346