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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-let-7b-5p AARSD1 -0.96 0 0.39 0.0002 miRNAWalker2 validate -0.22 0 NA
2 hsa-let-7b-5p AATF -0.96 0 0.62 0 miRNAWalker2 validate -0.25 0 NA
3 hsa-miR-148a-5p ABCB5 -0.77 0 1.74 1.0E-5 mirMAP -0.57 0 NA
4 hsa-let-7b-5p ABCC5 -0.96 0 1.23 0 miRNATAP -0.2 0 NA
5 hsa-miR-148a-5p ABCC5 -0.77 0 1.23 0 mirMAP -0.21 0 NA
6 hsa-miR-3607-3p ABCC5 -2.16 0 1.23 0 MirTarget; miRNATAP -0.15 0 NA
7 hsa-miR-199a-5p ABCC6P2 -1.99 0 0.58 0.00027 miRanda -0.13 0 NA
8 hsa-let-7b-5p ABCF1 -0.96 0 0.32 1.0E-5 miRNAWalker2 validate -0.12 0 NA
9 hsa-miR-148a-5p ABI2 -0.77 0 0.14 0.17339 miRNATAP -0.24 0 NA
10 hsa-miR-193b-3p ABI2 -0.17 0.27202 0.14 0.17339 miRNAWalker2 validate; MirTarget -0.24 0 NA
11 hsa-miR-374b-5p ABI2 -0.31 0.00301 0.14 0.17339 mirMAP -0.15 0.00242 NA
12 hsa-miR-30e-3p ABL2 -1.21 0 0.6 0 mirMAP -0.19 0 NA
13 hsa-miR-374b-5p ABR -0.31 0.00301 -0.28 0.11187 miRNATAP -0.37 1.0E-5 NA
14 hsa-let-7b-5p ACACA -0.96 0 0.78 0 miRNAWalker2 validate -0.25 0 NA
15 hsa-miR-30a-3p ACACA -1.53 0 0.78 0 mirMAP -0.16 0 NA
16 hsa-miR-30e-3p ACACA -1.21 0 0.78 0 mirMAP -0.17 0.00073 NA
17 hsa-miR-193b-3p ACBD6 -0.17 0.27202 1.02 0 miRNAWalker2 validate -0.12 0.00029 NA
18 hsa-let-7b-3p ACSL3 -1.22 0 0.05 0.65044 mirMAP -0.13 0.00013 NA
19 hsa-miR-195-3p ACSL3 -1.09 0 0.05 0.65044 mirMAP -0.13 0 NA
20 hsa-miR-30a-3p ACSL3 -1.53 0 0.05 0.65044 mirMAP -0.12 3.0E-5 NA
21 hsa-miR-30e-3p ACSL3 -1.21 0 0.05 0.65044 mirMAP -0.14 0.00094 NA
22 hsa-miR-195-3p ACSL4 -1.09 0 2.07 0 mirMAP -0.39 4.0E-5 NA
23 hsa-miR-374b-5p ACSL4 -0.31 0.00301 2.07 0 mirMAP -0.48 0.00583 NA
24 hsa-miR-148a-5p ACTG1 -0.77 0 -0.12 0.20938 MirTarget; miRNATAP -0.17 0 NA
25 hsa-miR-193b-3p ACTG1 -0.17 0.27202 -0.12 0.20938 miRNAWalker2 validate -0.18 0 NA
26 hsa-let-7b-3p ACTL6A -1.22 0 0.55 0 MirTarget -0.13 3.0E-5 NA
27 hsa-let-7f-1-3p ACTL6A -0.7 0 0.55 0 MirTarget -0.12 0.00039 NA
28 hsa-miR-199a-5p ACTN2 -1.99 0 1.96 2.0E-5 miRanda -0.23 0.00264 NA
29 hsa-miR-148a-5p ACTR3 -0.77 0 0.05 0.43435 mirMAP -0.12 0 NA
30 hsa-let-7b-3p ACVR2B -1.22 0 -0.24 0.05503 MirTarget -0.17 3.0E-5 NA
31 hsa-miR-30a-3p ADA -1.53 0 0.81 0 MirTarget -0.2 0 NA
32 hsa-miR-30e-3p ADA -1.21 0 0.81 0 MirTarget -0.4 0 NA
33 hsa-miR-3607-3p ADAM11 -2.16 0 1.25 0 miRNATAP -0.25 0 NA
34 hsa-miR-3607-3p ADAM12 -2.16 0 0.93 0.0022 mirMAP; miRNATAP -0.27 3.0E-5 NA
35 hsa-miR-374b-5p ADAM12 -0.31 0.00301 0.93 0.0022 mirMAP -0.57 8.0E-5 NA
36 hsa-miR-3607-3p ADAM22 -2.16 0 1.17 0.00038 mirMAP -0.3 2.0E-5 NA
37 hsa-let-7b-3p ADAM23 -1.22 0 1.53 0.00013 mirMAP -0.37 0.00396 NA
38 hsa-let-7f-1-3p ADAM23 -0.7 0 1.53 0.00013 mirMAP -0.39 0.00446 NA
39 hsa-miR-374b-5p ADAM28 -0.31 0.00301 -0.45 0.16409 mirMAP -0.52 0.00056 NA
40 hsa-miR-195-3p ADAM9 -1.09 0 0.47 0.00581 mirMAP -0.17 0.0001 NA
41 hsa-miR-148a-5p ADAMTS15 -0.77 0 -0.88 0.00206 mirMAP -0.4 1.0E-5 NA
42 hsa-miR-148a-5p ADAMTS5 -0.77 0 -0.16 0.36499 mirMAP; miRNATAP -0.31 0 NA
43 hsa-miR-193b-3p ADARB1 -0.17 0.27202 -0.13 0.22208 miRNAWalker2 validate; MirTarget -0.11 0.00093 NA
44 hsa-miR-199a-5p ADCK5 -1.99 0 0.84 0 miRanda -0.11 0 NA
45 hsa-let-7b-5p ADRM1 -0.96 0 0.19 0.01952 miRNAWalker2 validate -0.16 0 NA
46 hsa-miR-148a-5p ADSS -0.77 0 0.31 0.00033 MirTarget -0.11 4.0E-5 NA
47 hsa-let-7b-5p AEN -0.96 0 0.28 0.01239 MirTarget -0.16 2.0E-5 NA
48 hsa-miR-3607-3p AFAP1 -2.16 0 0.33 0.05949 mirMAP -0.15 7.0E-5 NA
49 hsa-let-7b-5p AFF2 -0.96 0 1.4 0.00046 MirTarget -0.39 0.00293 NA
50 hsa-let-7f-1-3p AFF2 -0.7 0 1.4 0.00046 mirMAP -0.52 0.00013 NA
51 hsa-miR-3607-3p AFF2 -2.16 0 1.4 0.00046 mirMAP -0.29 0.00066 NA
52 hsa-miR-3607-3p AFF3 -2.16 0 -0.32 0.28974 mirMAP; miRNATAP -0.17 0.0084 NA
53 hsa-miR-199a-5p AGBL5 -1.99 0 0.72 0 miRanda -0.13 0 NA
54 hsa-let-7b-5p AGFG2 -0.96 0 -0.02 0.87061 miRNAWalker2 validate -0.17 1.0E-5 NA
55 hsa-miR-148a-5p AGPAT4 -0.77 0 0.87 7.0E-5 mirMAP -0.25 0.00016 NA
56 hsa-miR-3607-3p AGPAT4 -2.16 0 0.87 7.0E-5 mirMAP -0.16 0.00056 NA
57 hsa-miR-374b-5p AHDC1 -0.31 0.00301 -0.23 0.02626 miRNATAP -0.14 0.0054 NA
58 hsa-miR-374b-5p AHI1 -0.31 0.00301 0.07 0.63637 MirTarget -0.2 0.00238 NA
59 hsa-miR-450b-5p AIDA -1.34 0 0.39 0 miRNATAP -0.12 0 NA
60 hsa-miR-29b-1-5p AIF1L -0.54 0.00103 0.76 0.0005 MirTarget -0.23 0.00049 NA
61 hsa-miR-374b-5p AIF1L -0.31 0.00301 0.76 0.0005 mirMAP -0.32 0.00237 NA
62 hsa-miR-30e-3p AKAP8 -1.21 0 0.3 0 MirTarget -0.11 0 NA
63 hsa-miR-199a-5p AKR1C2 -1.99 0 0.25 0.39842 miRanda -0.19 8.0E-5 NA
64 hsa-miR-199a-5p ALDH1L1 -1.99 0 -1.8 0 miRanda -0.21 0.00084 NA
65 hsa-miR-374b-5p ALDH1L2 -0.31 0.00301 0.46 0.04465 mirMAP -0.37 0.00046 NA
66 hsa-let-7b-5p ALG3 -0.96 0 0.6 0 miRNAWalker2 validate -0.23 0 NA
67 hsa-miR-199a-5p ALKBH2 -1.99 0 0.58 2.0E-5 miRanda -0.14 0 NA
68 hsa-miR-148a-5p ALPK3 -0.77 0 1.32 0 mirMAP -0.3 0.00022 NA
69 hsa-miR-30e-3p ALPK3 -1.21 0 1.32 0 mirMAP -0.36 0.00065 NA
70 hsa-miR-374b-5p AMOTL1 -0.31 0.00301 -0.53 0.02603 mirMAP -0.48 2.0E-5 NA
71 hsa-let-7b-5p AMT -0.96 0 -0.85 0 MirTarget -0.16 0.00457 NA
72 hsa-miR-450b-5p ANGEL2 -1.34 0 0.4 0 mirMAP -0.11 0 NA
73 hsa-miR-148a-5p ANK2 -0.77 0 -0.94 8.0E-5 MirTarget; miRNATAP -0.3 4.0E-5 NA
74 hsa-miR-199a-5p ANKAR -1.99 0 0.96 0 miRanda -0.12 0 NA
75 hsa-miR-30e-3p ANKDD1A -1.21 0 0.53 0.0002 MirTarget -0.25 1.0E-5 NA
76 hsa-miR-199a-5p ANKRD26P1 -1.99 0 0.43 0.21485 miRanda -0.16 0.00457 NA
77 hsa-miR-450b-5p ANKRD27 -1.34 0 0.9 0 PITA -0.12 0.00037 NA
78 hsa-miR-30e-3p ANKRD29 -1.21 0 1.13 4.0E-5 MirTarget; mirMAP -0.33 0.00303 NA
79 hsa-let-7b-3p ANKRD52 -1.22 0 1.46 0 mirMAP -0.31 0 NA
80 hsa-let-7b-5p ANKRD52 -0.96 0 1.46 0 miRNAWalker2 validate; mirMAP; miRNATAP -0.21 0 NA
81 hsa-let-7f-1-3p ANKRD52 -0.7 0 1.46 0 mirMAP -0.14 0.00159 NA
82 hsa-miR-148a-5p ANKRD52 -0.77 0 1.46 0 miRNATAP -0.2 0 NA
83 hsa-miR-29b-1-5p ANKRD52 -0.54 0.00103 1.46 0 mirMAP -0.15 6.0E-5 NA
84 hsa-miR-3607-3p ANKRD52 -2.16 0 1.46 0 miRNATAP -0.22 0 NA
85 hsa-let-7b-3p ANKS1B -1.22 0 1.43 0.00012 miRNATAP -0.39 0.00133 NA
86 hsa-miR-450b-5p ANKS1B -1.34 0 1.43 0.00012 PITA; miRNATAP -0.33 0.00256 NA
87 hsa-let-7b-5p ANKZF1 -0.96 0 0.85 0 miRNAWalker2 validate -0.25 0 NA
88 hsa-miR-30a-3p ANLN -1.53 0 3.89 0 MirTarget -0.56 0 NA
89 hsa-miR-30e-3p ANLN -1.21 0 3.89 0 MirTarget -0.77 0 NA
90 hsa-miR-3607-3p ANO4 -2.16 0 1.36 0 MirTarget; miRNATAP -0.28 1.0E-5 NA
91 hsa-miR-193b-3p ANP32B -0.17 0.27202 -0.02 0.80628 miRNAWalker2 validate -0.12 4.0E-5 NA
92 hsa-miR-374b-5p ANTXR1 -0.31 0.00301 -0.48 0.04009 MirTarget; mirMAP -0.44 6.0E-5 NA
93 hsa-miR-374b-5p ANXA4 -0.31 0.00301 -0.2 0.167 mirMAP -0.33 0 NA
94 hsa-let-7b-5p AP1S1 -0.96 0 0.55 0 MirTarget; miRNATAP -0.17 0 NA
95 hsa-let-7b-3p AP3B1 -1.22 0 0.63 0 mirMAP -0.14 0 NA
96 hsa-let-7f-1-3p AP3B1 -0.7 0 0.63 0 mirMAP -0.1 0.00013 NA
97 hsa-miR-193b-3p AP3M2 -0.17 0.27202 0.87 0 miRNAWalker2 validate -0.22 0 NA
98 hsa-miR-199a-5p APC2 -1.99 0 1.72 0 mirMAP -0.1 0.00178 NA
99 hsa-miR-193b-3p APCDD1 -0.17 0.27202 -1.3 0.00043 miRNAWalker2 validate -0.53 1.0E-5 NA
100 hsa-let-7b-5p APRT -0.96 0 0.19 0.12663 miRNAWalker2 validate -0.27 0 NA
101 hsa-let-7b-5p ARFIP2 -0.96 0 0.37 0 miRNAWalker2 validate -0.16 0 NA
102 hsa-let-7b-5p ARG2 -0.96 0 0.15 0.43591 MirTarget -0.18 0.00562 NA
103 hsa-miR-193b-3p ARHGAP19 -0.17 0.27202 0.49 0 miRNAWalker2 validate; mirMAP -0.14 0 NA
104 hsa-miR-29b-1-5p ARHGAP19 -0.54 0.00103 0.49 0 mirMAP -0.13 0 NA
105 hsa-let-7f-1-3p ARHGAP28 -0.7 0 0.59 0.03308 mirMAP -0.27 0.00485 NA
106 hsa-miR-148a-5p ARHGAP31 -0.77 0 -0.42 0.00347 mirMAP -0.14 0.00129 NA
107 hsa-miR-374b-5p ARHGAP6 -0.31 0.00301 0.22 0.19399 mirMAP; miRNATAP -0.26 0.00099 NA
108 hsa-miR-148a-5p ARHGEF18 -0.77 0 0.5 0 MirTarget; miRNATAP -0.12 0 NA
109 hsa-miR-193b-3p ARHGEF18 -0.17 0.27202 0.5 0 mirMAP -0.17 0 NA
110 hsa-miR-3607-3p ARHGEF3 -2.16 0 0.51 0.00381 MirTarget; miRNATAP -0.12 0.00127 NA
111 hsa-let-7b-5p ARID3A -0.96 0 1.53 0 miRNAWalker2 validate -0.38 1.0E-5 NA
112 hsa-let-7b-5p ARID3B -0.96 0 0.46 0.00021 miRNAWalker2 validate; miRNATAP -0.14 0.00075 NA
113 hsa-miR-193b-3p ARID3B -0.17 0.27202 0.46 0.00021 MirTarget -0.19 0 NA
114 hsa-miR-148a-5p ARID5B -0.77 0 -0.52 0.00012 mirMAP -0.17 3.0E-5 NA
115 hsa-miR-193b-3p ARL10 -0.17 0.27202 -0.42 0.01556 mirMAP -0.18 0.00149 NA
116 hsa-miR-450b-5p ARMC1 -1.34 0 0.39 0.0001 MirTarget; mirMAP -0.11 0.00015 NA
117 hsa-miR-450b-5p ARPC5 -1.34 0 0.69 0 MirTarget; PITA; mirMAP -0.14 0 NA
118 hsa-let-7b-3p ARSB -1.22 0 0 0.99867 mirMAP -0.16 8.0E-5 NA
119 hsa-let-7f-1-3p ARSB -0.7 0 0 0.99867 mirMAP -0.16 0.00033 NA
120 hsa-miR-148a-5p ASAH1 -0.77 0 -0.44 0.00056 MirTarget; miRNATAP -0.22 0 NA
121 hsa-miR-3607-3p ASAP1 -2.16 0 0.6 1.0E-5 MirTarget; mirMAP; miRNATAP -0.1 0.00049 NA
122 hsa-let-7f-1-3p ASAP2 -0.7 0 0.69 2.0E-5 MirTarget -0.15 0.00778 NA
123 hsa-miR-30e-3p ASB1 -1.21 0 0.21 0.0408 mirMAP -0.18 0 NA
124 hsa-miR-199a-5p ASB4 -1.99 0 -0.62 0.06683 miRanda -0.17 0.0018 NA
125 hsa-miR-374b-5p ASCC3 -0.31 0.00301 0.03 0.78425 mirMAP -0.21 0.0001 NA
126 hsa-let-7b-5p ASNA1 -0.96 0 0.58 0 miRNAWalker2 validate -0.19 0 NA
127 hsa-miR-450b-5p ASPH -1.34 0 0.47 0.00525 MirTarget -0.15 0.00224 NA
128 hsa-let-7b-5p ASPSCR1 -0.96 0 0.72 1.0E-5 miRNAWalker2 validate -0.43 0 NA
129 hsa-let-7b-3p ASXL1 -1.22 0 0.64 0 miRNATAP -0.16 0 NA
130 hsa-miR-193b-3p ASXL1 -0.17 0.27202 0.64 0 miRNAWalker2 validate -0.13 0 NA
131 hsa-miR-193b-3p ATAD2 -0.17 0.27202 1.43 0 miRNAWalker2 validate -0.21 0.00024 NA
132 hsa-let-7b-5p ATAD3B -0.96 0 0.76 0 miRNAWalker2 validate -0.29 0 NA
133 hsa-let-7b-3p ATAD5 -1.22 0 1.62 0 MirTarget -0.3 0 NA
134 hsa-let-7f-1-3p ATAD5 -0.7 0 1.62 0 MirTarget -0.22 0.00173 NA
135 hsa-let-7b-5p ATG10 -0.96 0 0.35 0.00052 MirTarget -0.2 0 NA
136 hsa-let-7b-5p ATG4B -0.96 0 0.37 0 miRNAWalker2 validate; miRNATAP -0.12 0 NA
137 hsa-let-7b-5p ATOX1 -0.96 0 0.43 0.00496 miRNAWalker2 validate -0.25 0 NA
138 hsa-miR-199a-5p ATOX1 -1.99 0 0.43 0.00496 mirMAP -0.11 0 NA
139 hsa-miR-3607-3p ATP10B -2.16 0 -0.24 0.56639 MirTarget -0.24 0.00744 NA
140 hsa-miR-193b-3p ATP13A2 -0.17 0.27202 0.92 0 miRNAWalker2 validate -0.15 0.00012 NA
141 hsa-miR-193b-3p ATP1A1 -0.17 0.27202 0.44 0.00034 miRNAWalker2 validate -0.19 0 NA
142 hsa-miR-374b-5p ATP1A1 -0.31 0.00301 0.44 0.00034 miRNATAP -0.19 0.00112 NA
143 hsa-let-7b-3p ATP2B1 -1.22 0 -0.16 0.1608 MirTarget; miRNATAP -0.11 0.00385 NA
144 hsa-miR-30a-3p ATP2B2 -1.53 0 -0.4 0.15518 mirMAP -0.22 0.00279 NA
145 hsa-let-7b-3p ATP5E -1.22 0 0.38 0.00141 mirMAP -0.24 0 NA
146 hsa-miR-450b-5p ATP5E -1.34 0 0.38 0.00141 mirMAP -0.18 0 NA
147 hsa-let-7b-5p ATP6V0A1 -0.96 0 0.28 0.00395 miRNAWalker2 validate -0.12 0.00032 NA
148 hsa-let-7b-3p ATP6V1C1 -1.22 0 0.88 0 mirMAP -0.23 0 NA
149 hsa-miR-195-3p ATP6V1C1 -1.09 0 0.88 0 mirMAP -0.19 0 NA
150 hsa-miR-450b-5p ATP6V1C1 -1.34 0 0.88 0 mirMAP -0.2 0 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 CELL CYCLE 185 1316 2.884e-17 1.342e-13
2 CELL CYCLE PROCESS 158 1081 2.411e-16 5.61e-13
3 MITOTIC CELL CYCLE 121 766 3.678e-15 5.704e-12
4 CELL DIVISION 77 460 2.629e-11 3.058e-08
5 NEGATIVE REGULATION OF GENE EXPRESSION 178 1493 3.274e-10 3.047e-07
6 MITOTIC NUCLEAR DIVISION 62 361 8.113e-10 6.292e-07
7 CYTOSKELETON ORGANIZATION 112 838 1.736e-09 1.042e-06
8 REGULATION OF CELL CYCLE 123 949 1.792e-09 1.042e-06
9 MICROTUBULE CYTOSKELETON ORGANIZATION 59 348 3.433e-09 1.775e-06
10 NEGATIVE REGULATION OF CELL CYCLE 68 433 5.925e-09 2.757e-06
11 DNA REPLICATION 41 208 1.126e-08 4.763e-06
12 DNA METABOLIC PROCESS 101 758 1.32e-08 5.12e-06
13 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 173 1517 1.632e-08 5.841e-06
14 NEGATIVE REGULATION OF CELL CYCLE PROCESS 41 214 2.626e-08 8.727e-06
15 CELL CYCLE CHECKPOINT 38 194 4.567e-08 1.417e-05
16 CELL CYCLE PHASE TRANSITION 45 255 7.35e-08 2.026e-05
17 NEGATIVE REGULATION OF ORGANELLE ORGANIZATION 60 387 7.402e-08 2.026e-05
18 MICROTUBULE BASED PROCESS 74 522 1.034e-07 2.673e-05
19 EMBRYO DEVELOPMENT 111 894 1.15e-07 2.678e-05
20 NCRNA METABOLIC PROCESS 75 533 1.151e-07 2.678e-05
21 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 123 1021 1.258e-07 2.787e-05
22 RIBONUCLEOPROTEIN COMPLEX BIOGENESIS 65 440 1.358e-07 2.872e-05
23 RIBOSOME BIOGENESIS 50 308 2.149e-07 4.347e-05
24 RNA PROCESSING 104 835 2.51e-07 4.685e-05
25 CELL PROLIFERATION 88 672 2.517e-07 4.685e-05
26 ORGANELLE FISSION 70 496 2.714e-07 4.761e-05
27 PROTEIN LOCALIZATION 193 1805 2.763e-07 4.761e-05
28 REGULATION OF MICROTUBULE POLYMERIZATION OR DEPOLYMERIZATION 34 178 4.269e-07 7.094e-05
29 NEUROGENESIS 155 1402 6.722e-07 0.0001079
30 NCRNA PROCESSING 57 386 8.034e-07 0.0001246
31 REGULATION OF MICROTUBULE BASED PROCESS 41 243 9.375e-07 0.0001343
32 REGULATION OF PROTEIN COMPLEX DISASSEMBLY 38 217 9.07e-07 0.0001343
33 CELLULAR MACROMOLECULE LOCALIZATION 139 1234 9.528e-07 0.0001343
34 MACROMOLECULAR COMPLEX ASSEMBLY 153 1398 1.447e-06 0.0001923
35 REGULATION OF CELL CYCLE PROCESS 74 558 1.416e-06 0.0001923
36 EPITHELIUM DEVELOPMENT 111 945 1.815e-06 0.0002346
37 TISSUE DEVELOPMENT 163 1518 2.021e-06 0.0002541
38 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 35 199 2.175e-06 0.000262
39 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 141 1275 2.196e-06 0.000262
40 REGULATION OF MITOTIC CELL CYCLE 64 468 2.596e-06 0.000302
41 EMBRYONIC MORPHOGENESIS 71 539 2.942e-06 0.0003339
42 REGULATION OF CELL MORPHOGENESIS 72 552 3.58e-06 0.0003966
43 NEGATIVE REGULATION OF PROTEIN COMPLEX DISASSEMBLY 31 170 3.761e-06 0.0003988
44 NEGATIVE REGULATION OF CYTOSKELETON ORGANIZATION 37 221 3.771e-06 0.0003988
45 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 72 554 4.075e-06 0.0004214
46 CELLULAR RESPONSE TO DNA DAMAGE STIMULUS 88 720 4.598e-06 0.0004651
47 MORPHOGENESIS OF AN EPITHELIUM 56 400 5.33e-06 0.0005167
48 REGULATION OF CELL PROJECTION ORGANIZATION 72 558 5.263e-06 0.0005167
49 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 110 957 5.511e-06 0.0005233
50 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 84 684 6.295e-06 0.0005858
51 TUBE DEVELOPMENT 71 552 6.824e-06 0.0006226
52 CELL CYCLE G1 S PHASE TRANSITION 23 111 7.527e-06 0.0006486
53 G1 S TRANSITION OF MITOTIC CELL CYCLE 23 111 7.527e-06 0.0006486
54 REGULATION OF CELL PROLIFERATION 158 1496 7.516e-06 0.0006486
55 CHROMOSOME ORGANIZATION 114 1009 8.227e-06 0.0006931
56 SKELETAL SYSTEM DEVELOPMENT 61 455 8.342e-06 0.0006931
57 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 173 1672 9.067e-06 0.0007073
58 POSITIVE REGULATION OF CELL CYCLE PROCESS 39 247 8.851e-06 0.0007073
59 PROTEIN LOCALIZATION TO ORGANELLE 71 556 8.76e-06 0.0007073
60 REGULATION OF CELL CYCLE PHASE TRANSITION 47 321 9.12e-06 0.0007073
61 REGULATION OF CELL DIFFERENTIATION 157 1492 9.854e-06 0.0007278
62 REGULATION OF NEURON PROJECTION DEVELOPMENT 56 408 9.678e-06 0.0007278
63 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 45 303 9.698e-06 0.0007278
64 ORGAN MORPHOGENESIS 98 841 1.028e-05 0.0007358
65 PROTEIN COMPLEX SUBUNIT ORGANIZATION 160 1527 1.02e-05 0.0007358
66 TUBE MORPHOGENESIS 47 323 1.077e-05 0.0007594
67 DNA INTEGRITY CHECKPOINT 27 146 1.191e-05 0.0008268
68 SPINDLE ASSEMBLY 17 70 1.291e-05 0.0008834
69 CELL PROJECTION ORGANIZATION 103 902 1.452e-05 0.000979
70 REGULATION OF CARDIAC MUSCLE CELL CONTRACTION 10 27 1.495e-05 0.0009936
71 ESTABLISHMENT OF LOCALIZATION IN CELL 172 1676 1.543e-05 0.001004
72 REGULATION OF ORGANELLE ORGANIZATION 128 1178 1.553e-05 0.001004
73 ORGANELLE ASSEMBLY 64 495 1.626e-05 0.001037
74 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 86 724 1.759e-05 0.001106
75 RRNA METABOLIC PROCESS 39 255 1.884e-05 0.001169
76 POSTTRANSCRIPTIONAL REGULATION OF GENE EXPRESSION 59 448 1.998e-05 0.001223
77 SISTER CHROMATID SEGREGATION 30 176 2.117e-05 0.001279
78 REGULATION OF CELL DEVELOPMENT 96 836 2.275e-05 0.001357
79 REGULATION OF CYTOSKELETON ORGANIZATION 64 502 2.523e-05 0.001486
80 REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 49 354 2.733e-05 0.001589
81 ESTABLISHMENT OF PROTEIN LOCALIZATION 148 1423 3.266e-05 0.001876
82 TRANSLATIONAL INITIATION 26 146 3.393e-05 0.001889
83 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 26 146 3.393e-05 0.001889
84 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 123 1142 3.41e-05 0.001889
85 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 179 1784 3.724e-05 0.002039
86 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 87 750 3.799e-05 0.002055
87 MITOTIC CELL CYCLE CHECKPOINT 25 139 4.017e-05 0.002148
88 DNA DEPENDENT DNA REPLICATION 20 99 4.259e-05 0.002226
89 MITOTIC SPINDLE ORGANIZATION 16 69 4.257e-05 0.002226
90 MICROTUBULE ORGANIZING CENTER ORGANIZATION 18 84 4.485e-05 0.002319
91 POSITIVE REGULATION OF GENE EXPRESSION 174 1733 4.656e-05 0.002355
92 POSITIVE REGULATION OF CELL CYCLE 46 332 4.637e-05 0.002355
93 CARDIOVASCULAR SYSTEM DEVELOPMENT 90 788 4.989e-05 0.002469
94 CIRCULATORY SYSTEM DEVELOPMENT 90 788 4.989e-05 0.002469
95 PROTEIN COMPLEX BIOGENESIS 121 1132 5.514e-05 0.002673
96 PROTEIN COMPLEX ASSEMBLY 121 1132 5.514e-05 0.002673
97 CELLULAR COMPONENT MORPHOGENESIS 100 900 5.739e-05 0.002753
98 MRNA METABOLIC PROCESS 73 611 6.211e-05 0.002949
99 CHROMATIN MODIFICATION 66 539 6.637e-05 0.00312
100 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 179 1805 7.085e-05 0.003297
101 ORGANIC ACID TRANSMEMBRANE TRANSPORT 20 103 7.666e-05 0.003531
102 REGULATION OF ACTIN FILAMENT BASED MOVEMENT 10 32 8.064e-05 0.003678
103 TISSUE MORPHOGENESIS 65 533 8.481e-05 0.003822
104 REGULATION OF NEURON DIFFERENTIATION 67 554 8.543e-05 0.003822
105 ESTABLISHMENT OF PROTEIN LOCALIZATION TO ENDOPLASMIC RETICULUM 20 104 8.827e-05 0.003872
106 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 143 1395 8.904e-05 0.003872
107 NEGATIVE REGULATION OF CHROMOSOME ORGANIZATION 19 96 8.781e-05 0.003872
108 POSITIVE REGULATION OF CELL DIFFERENTIATION 92 823 9.087e-05 0.003915
109 REGULATION OF CELL CYCLE G2 M PHASE TRANSITION 14 59 9.687e-05 0.004135
110 LOCOMOTION 118 1114 9.987e-05 0.004225
111 G2 DNA DAMAGE CHECKPOINT 10 33 0.0001079 0.004524
112 NEGATIVE REGULATION OF CELL DIVISION 14 60 0.0001177 0.004845
113 CELLULAR RESPONSE TO STRESS 157 1565 0.0001168 0.004845
114 PROTEIN LOCALIZATION TO ENDOPLASMIC RETICULUM 22 123 0.0001239 0.005057
115 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 45 337 0.0001342 0.005393
116 MITOTIC SISTER CHROMATID SEGREGATION 18 91 0.0001344 0.005393
117 VASCULATURE DEVELOPMENT 58 469 0.0001376 0.005473
118 CELL MOTILITY 92 835 0.0001521 0.005947
119 LOCALIZATION OF CELL 92 835 0.0001521 0.005947
120 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 164 1656 0.0001557 0.005988
121 MITOTIC DNA INTEGRITY CHECKPOINT 19 100 0.000155 0.005988
122 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 62 513 0.0001576 0.006011
123 APPENDAGE DEVELOPMENT 27 169 0.0001657 0.006167
124 LIMB DEVELOPMENT 27 169 0.0001657 0.006167
125 REGULATION OF CELLULAR COMPONENT MOVEMENT 86 771 0.0001645 0.006167
126 CHROMOSOME SEGREGATION 38 272 0.0001721 0.006343
127 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 120 1152 0.0001745 0.006343
128 REGULATION OF CELL GROWTH 50 391 0.0001735 0.006343
129 PALATE DEVELOPMENT 17 85 0.0001776 0.006358
130 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 83 740 0.0001776 0.006358
131 HEAD DEVELOPMENT 80 709 0.0001911 0.006787
132 DNA REPLICATION INITIATION 9 29 0.0001947 0.006862
133 REGULATION OF SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR 26 162 0.0002013 0.007043
134 NEURAL TUBE FORMATION 18 94 0.0002065 0.007171
135 NUCLEAR CHROMOSOME SEGREGATION 33 228 0.0002321 0.008
136 RESPONSE TO NUTRIENT 29 191 0.0002392 0.008182
137 CELL DEVELOPMENT 143 1426 0.000242 0.00822
138 CARTILAGE DEVELOPMENT 24 147 0.0002675 0.009019
139 ACTIN FILAMENT BASED PROCESS 55 450 0.0002729 0.009136
140 CENTRAL NERVOUS SYSTEM DEVELOPMENT 94 872 0.0002784 0.009252
141 EMBRYONIC ORGAN MORPHOGENESIS 38 279 0.0002895 0.009529
142 POSITIVE REGULATION OF CELL DEVELOPMENT 57 472 0.0002908 0.009529
143 PROTEIN TARGETING TO MEMBRANE 25 157 0.0002993 0.00974
NumGOOverlapSizeP ValueAdj. P Value
1 RNA BINDING 202 1598 6.533e-14 6.069e-11
2 POLY A RNA BINDING 154 1170 4.008e-12 1.862e-09
3 RIBONUCLEOTIDE BINDING 210 1860 8.807e-10 2.727e-07
4 PROTEIN DOMAIN SPECIFIC BINDING 85 624 7.215e-08 1.676e-05
5 ADENYL NUCLEOTIDE BINDING 168 1514 1.711e-07 3.179e-05
6 MACROMOLECULAR COMPLEX BINDING 154 1399 9.476e-07 0.0001467
7 MRNA BINDING 29 155 4.525e-06 0.0006005
8 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 73 588 1.746e-05 0.001802
9 ENZYME BINDING 177 1737 1.73e-05 0.001802
10 TRANSCRIPTION COACTIVATOR ACTIVITY 43 296 2.616e-05 0.00243
11 CHAPERONE BINDING 17 81 9.525e-05 0.008044
NumGOOverlapSizeP ValueAdj. P Value
1 NUCLEOLUS 122 848 2.416e-12 1.411e-09
2 CHROMOSOME 111 880 5.025e-08 1.467e-05
3 SPINDLE 48 289 1.858e-07 3.617e-05
4 PCG PROTEIN COMPLEX 15 43 2.76e-07 4.029e-05
5 MICROTUBULE CYTOSKELETON 125 1068 4.788e-07 5.593e-05
6 CELL JUNCTION 130 1151 1.901e-06 0.000185
7 RIBONUCLEOPROTEIN COMPLEX 88 721 4.86e-06 0.0004055
8 ANCHORING JUNCTION 65 489 5.67e-06 0.0004139
9 CYTOSKELETON 199 1967 7.719e-06 0.0005009
10 EUCHROMATIN 11 31 9.015e-06 0.0005265
11 MICROTUBULE 55 405 1.578e-05 0.000838
12 CELL SUBSTRATE JUNCTION 54 398 1.928e-05 0.0009385
13 EXCITATORY SYNAPSE 32 197 3.096e-05 0.001292
14 HETEROCHROMATIN 16 67 2.887e-05 0.001292
15 CHROMOSOME CENTROMERIC REGION 29 174 4.421e-05 0.001721
16 NUCLEAR CHROMOSOME 65 523 4.808e-05 0.001755
17 SPINDLE MICROTUBULE 14 58 7.934e-05 0.002726
18 SPINDLE MIDZONE 9 27 0.0001046 0.003392
19 CYTOSKELETAL PART 146 1436 0.0001104 0.003394
20 CONDENSED CHROMOSOME 30 195 0.0001486 0.004338
21 CHROMATIN 55 441 0.0001629 0.004531
22 POSTSYNAPSE 48 378 0.0002728 0.007242
23 CENTROSOME 58 487 0.0003697 0.009244
24 SUPRAMOLECULAR FIBER 75 670 0.0003799 0.009244

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04110_Cell_cycle 28 128 2.483e-07 4.47e-05
2 hsa00240_Pyrimidine_metabolism 19 99 0.000135 0.01215
3 hsa04390_Hippo_signaling_pathway 25 154 0.0002206 0.01324
4 hsa04540_Gap_junction 17 90 0.000363 0.01459
5 hsa03010_Ribosome 17 92 0.0004745 0.01459
6 hsa00230_Purine_metabolism 25 162 0.0004863 0.01459
7 hsa04510_Focal_adhesion 28 200 0.001125 0.02893
8 hsa00670_One_carbon_pool_by_folate 6 18 0.001541 0.03468
9 hsa00100_Steroid_biosynthesis 6 19 0.00211 0.0395
10 hsa04310_Wnt_signaling_pathway 22 151 0.002194 0.0395
11 hsa03030_DNA_replication 8 36 0.004652 0.06644
12 hsa04666_Fc_gamma_R.mediated_phagocytosis 15 95 0.004914 0.06644
13 hsa03020_RNA_polymerase 7 29 0.004915 0.06644
14 hsa04115_p53_signaling_pathway 12 69 0.005168 0.06644
15 hsa04730_Long.term_depression 12 70 0.005818 0.06806
16 hsa00910_Nitrogen_metabolism 6 23 0.00605 0.06806
17 hsa04360_Axon_guidance 18 130 0.008937 0.09434
18 hsa04142_Lysosome 17 121 0.009434 0.09434
19 hsa04810_Regulation_of_actin_cytoskeleton 26 214 0.01099 0.09935
20 hsa04512_ECM.receptor_interaction 13 85 0.01104 0.09935
21 hsa04114_Oocyte_meiosis 16 114 0.01167 0.1
22 hsa04014_Ras_signaling_pathway 27 236 0.02013 0.1606
23 hsa04520_Adherens_junction 11 73 0.02052 0.1606
24 hsa04330_Notch_signaling_pathway 8 47 0.02322 0.1741
25 hsa04151_PI3K_AKT_signaling_pathway 37 351 0.02476 0.1782
26 hsa04710_Circadian_rhythm_._mammal 5 23 0.0261 0.1807
27 hsa04012_ErbB_signaling_pathway 12 87 0.03007 0.2005
28 hsa04070_Phosphatidylinositol_signaling_system 11 78 0.03192 0.2052
29 hsa04664_Fc_epsilon_RI_signaling_pathway 11 79 0.03465 0.209
30 hsa00450_Selenocompound_metabolism 4 17 0.03483 0.209
31 hsa04916_Melanogenesis 13 101 0.04042 0.2347
32 hsa00534_Glycosaminoglycan_biosynthesis_._heparan_sulfate 5 26 0.04235 0.2382
33 hsa04145_Phagosome 18 156 0.04719 0.2574
34 hsa04144_Endocytosis 22 203 0.05516 0.292
35 hsa03040_Spliceosome 15 128 0.05894 0.2955
36 hsa04370_VEGF_signaling_pathway 10 76 0.05911 0.2955
37 hsa04010_MAPK_signaling_pathway 27 268 0.07657 0.3502
38 hsa04530_Tight_junction 15 133 0.07677 0.3502
39 hsa04912_GnRH_signaling_pathway 12 101 0.07809 0.3502
40 hsa00564_Glycerophospholipid_metabolism 10 80 0.07814 0.3502
41 hsa04720_Long.term_potentiation 9 70 0.07977 0.3502
42 hsa03450_Non.homologous_end.joining 3 14 0.08357 0.3582
43 hsa03060_Protein_export 4 23 0.09081 0.3715
44 hsa03430_Mismatch_repair 4 23 0.09081 0.3715
45 hsa00900_Terpenoid_backbone_biosynthesis 3 15 0.09884 0.3954
46 hsa04120_Ubiquitin_mediated_proteolysis 15 139 0.1024 0.4007
47 hsa04350_TGF.beta_signaling_pathway 10 85 0.1067 0.4086
48 hsa03013_RNA_transport 16 152 0.1107 0.415
49 hsa04914_Progesterone.mediated_oocyte_maturation 10 87 0.1196 0.4393
50 hsa00562_Inositol_phosphate_metabolism 7 57 0.1362 0.4904
51 hsa04972_Pancreatic_secretion 11 101 0.1398 0.4933
52 hsa04974_Protein_digestion_and_absorption 9 81 0.1564 0.5414
53 hsa04270_Vascular_smooth_muscle_contraction 12 116 0.1653 0.5569
54 hsa00531_Glycosaminoglycan_degradation 3 19 0.1691 0.5569
55 hsa00430_Taurine_and_hypotaurine_metabolism 2 10 0.1714 0.5569
56 hsa03015_mRNA_surveillance_pathway 9 83 0.1733 0.5569
57 hsa04660_T_cell_receptor_signaling_pathway 11 108 0.1915 0.6016
58 hsa04971_Gastric_acid_secretion 8 74 0.1938 0.6016
59 hsa04662_B_cell_receptor_signaling_pathway 8 75 0.2037 0.6215
60 hsa04960_Aldosterone.regulated_sodium_reabsorption 5 42 0.2081 0.6243
61 hsa04970_Salivary_secretion 9 89 0.2283 0.6737
62 hsa03410_Base_excision_repair 4 34 0.2529 0.7341
63 hsa03008_Ribosome_biogenesis_in_eukaryotes 8 81 0.2668 0.7621
64 hsa00051_Fructose_and_mannose_metabolism 4 36 0.2872 0.7832
65 hsa00270_Cysteine_and_methionine_metabolism 4 36 0.2872 0.7832
66 hsa00563_Glycosylphosphatidylinositol.GPI..anchor_biosynthesis 3 25 0.2915 0.7832
67 hsa04320_Dorso.ventral_axis_formation 3 25 0.2915 0.7832
68 hsa00561_Glycerolipid_metabolism 5 50 0.3254 0.8578
69 hsa00030_Pentose_phosphate_pathway 3 27 0.334 0.8578
70 hsa04966_Collecting_duct_acid_secretion 3 27 0.334 0.8578
71 hsa00970_Aminoacyl.tRNA_biosynthesis 6 63 0.3395 0.8578
72 hsa00770_Pantothenate_and_CoA_biosynthesis 2 16 0.3431 0.8578
73 hsa03440_Homologous_recombination 3 28 0.3553 0.8605
74 hsa04020_Calcium_signaling_pathway 15 177 0.3594 0.8605
75 hsa04260_Cardiac_muscle_contraction 7 77 0.3624 0.8605
76 hsa04722_Neurotrophin_signaling_pathway 11 127 0.3633 0.8605
77 hsa04670_Leukocyte_transendothelial_migration 10 117 0.3896 0.8863
78 hsa04141_Protein_processing_in_endoplasmic_reticulum 14 168 0.3906 0.8863
79 hsa00512_Mucin_type_O.Glycan_biosynthesis 3 30 0.3974 0.8863
80 hsa00630_Glyoxylate_and_dicarboxylate_metabolism 2 18 0.3988 0.8863
81 hsa04340_Hedgehog_signaling_pathway 5 56 0.4173 0.9157
82 hsa02010_ABC_transporters 4 44 0.4273 0.9157
83 hsa03320_PPAR_signaling_pathway 6 70 0.4359 0.923
84 hsa01040_Biosynthesis_of_unsaturated_fatty_acids 2 21 0.4779 1
85 hsa00532_Glycosaminoglycan_biosynthesis_._chondroitin_sulfate 2 22 0.5028 1
86 hsa00565_Ether_lipid_metabolism 3 36 0.5178 1
87 hsa04964_Proximal_tubule_bicarbonate_reclamation 2 23 0.527 1
88 hsa04977_Vitamin_digestion_and_absorption 2 24 0.5503 1
89 hsa04150_mTOR_signaling_pathway 4 52 0.5594 1
90 hsa04650_Natural_killer_cell_mediated_cytotoxicity 10 136 0.5817 1
91 hsa00330_Arginine_and_proline_metabolism 4 54 0.5898 1
92 hsa00620_Pyruvate_metabolism 3 40 0.5904 1
93 hsa04920_Adipocytokine_signaling_pathway 5 68 0.5906 1
94 hsa04910_Insulin_signaling_pathway 10 138 0.6005 1
95 hsa00052_Galactose_metabolism 2 27 0.6153 1
96 hsa03018_RNA_degradation 5 71 0.6294 1
97 hsa00340_Histidine_metabolism 2 29 0.6545 1
98 hsa04973_Carbohydrate_digestion_and_absorption 3 44 0.6556 1
99 hsa00590_Arachidonic_acid_metabolism 4 59 0.6601 1
100 hsa04621_NOD.like_receptor_signaling_pathway 4 59 0.6601 1
101 hsa03420_Nucleotide_excision_repair 3 45 0.6707 1
102 hsa00020_Citrate_cycle_.TCA_cycle. 2 30 0.6729 1
103 hsa04062_Chemokine_signaling_pathway 13 189 0.677 1
104 hsa00250_Alanine._aspartate_and_glutamate_metabolism 2 32 0.7072 1
105 hsa00260_Glycine._serine_and_threonine_metabolism 2 32 0.7072 1
106 hsa00520_Amino_sugar_and_nucleotide_sugar_metabolism 3 48 0.713 1
107 hsa00510_N.Glycan_biosynthesis 3 49 0.7261 1
108 hsa00010_Glycolysis_._Gluconeogenesis 4 65 0.7331 1
109 hsa04140_Regulation_of_autophagy 2 34 0.7385 1
110 hsa00480_Glutathione_metabolism 3 50 0.7387 1
111 hsa04210_Apoptosis 5 89 0.8113 1
112 hsa04514_Cell_adhesion_molecules_.CAMs. 8 136 0.8144 1
113 hsa00600_Sphingolipid_metabolism 2 40 0.8156 1
114 hsa00071_Fatty_acid_metabolism 2 43 0.846 1
115 hsa00860_Porphyrin_and_chlorophyll_metabolism 2 43 0.846 1
116 hsa04612_Antigen_processing_and_presentation 4 78 0.8497 1
117 hsa00280_Valine._leucine_and_isoleucine_degradation 2 44 0.8551 1
118 hsa00310_Lysine_degradation 2 44 0.8551 1
119 hsa04146_Peroxisome 4 79 0.8565 1
120 hsa00190_Oxidative_phosphorylation 7 132 0.8783 1
121 hsa04610_Complement_and_coagulation_cascades 3 69 0.9014 1
122 hsa04640_Hematopoietic_cell_lineage 4 88 0.907 1
123 hsa04976_Bile_secretion 3 71 0.9117 1
124 hsa00983_Drug_metabolism_._other_enzymes 2 52 0.9118 1
125 hsa04623_Cytosolic_DNA.sensing_pathway 2 56 0.9316 1
126 hsa00140_Steroid_hormone_biosynthesis 2 57 0.9358 1
127 hsa04630_Jak.STAT_signaling_pathway 6 155 0.9796 1
128 hsa04380_Osteoclast_differentiation 4 128 0.9893 1
129 hsa04620_Toll.like_receptor_signaling_pathway 2 102 0.9969 1
130 hsa04740_Olfactory_transduction 3 388 1 1

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1 SNHG1 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-148a-5p;hsa-miR-193b-3p;hsa-miR-195-3p;hsa-miR-24-1-5p;hsa-miR-30a-3p;hsa-miR-30e-3p;hsa-miR-3607-3p;hsa-miR-450b-5p 11 HELLS Sponge network 2.013 0 2.623 0 0.703
2 RP5-1074L1.4 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-148a-5p;hsa-miR-195-3p;hsa-miR-199a-5p;hsa-miR-24-1-5p;hsa-miR-29b-1-5p;hsa-miR-30a-3p;hsa-miR-3607-3p;hsa-miR-450b-5p 11 HELLS Sponge network 2.302 0 2.623 0 0.638
3 RP11-196G18.22 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-148a-5p;hsa-miR-195-3p;hsa-miR-199a-5p;hsa-miR-24-1-5p;hsa-miR-30a-3p;hsa-miR-30e-3p;hsa-miR-3607-3p 10 HELLS Sponge network 2.705 0 2.623 0 0.597
4 AP001469.9 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-148a-5p;hsa-miR-193b-3p;hsa-miR-195-3p;hsa-miR-199a-5p;hsa-miR-29b-1-5p;hsa-miR-30a-3p;hsa-miR-30e-3p;hsa-miR-3607-3p 11 HELLS Sponge network 2.428 0 2.623 0 0.592
5 RP1-228H13.5 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-148a-5p;hsa-miR-193b-3p;hsa-miR-195-3p;hsa-miR-24-1-5p;hsa-miR-30a-3p;hsa-miR-30e-3p;hsa-miR-3607-3p 10 HELLS Sponge network 1.554 0 2.623 0 0.591
6 KB-1572G7.2 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-148a-5p;hsa-miR-193b-3p;hsa-miR-24-1-5p;hsa-miR-30a-3p;hsa-miR-30e-3p;hsa-miR-3607-3p;hsa-miR-374b-5p 10 HELLS Sponge network 2.124 0 2.623 0 0.584
7 RP11-1246C19.1 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-148a-5p;hsa-miR-193b-3p;hsa-miR-195-3p;hsa-miR-199a-5p;hsa-miR-24-1-5p;hsa-miR-30a-3p;hsa-miR-450b-5p 10 HELLS Sponge network 2.721 0 2.623 0 0.564
8 GUSBP11 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-148a-5p;hsa-miR-193b-3p;hsa-miR-195-3p;hsa-miR-24-1-5p;hsa-miR-29b-1-5p;hsa-miR-30a-3p;hsa-miR-30e-3p;hsa-miR-3607-3p;hsa-miR-374b-5p 12 HELLS Sponge network 2.066 0 2.623 0 0.541
9 NPSR1-AS1 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-148a-5p;hsa-miR-195-3p;hsa-miR-199a-5p;hsa-miR-24-1-5p;hsa-miR-30a-3p;hsa-miR-30e-3p;hsa-miR-3607-3p;hsa-miR-450b-5p 11 HELLS Sponge network 5.28 0 2.623 0 0.53
10 CTC-459F4.3 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-148a-5p;hsa-miR-193b-3p;hsa-miR-195-3p;hsa-miR-24-1-5p;hsa-miR-30a-3p;hsa-miR-30e-3p;hsa-miR-3607-3p 10 HELLS Sponge network 1.207 0 2.623 0 0.51
11 RP5-1120P11.1 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-148a-5p;hsa-miR-193b-3p;hsa-miR-195-3p;hsa-miR-199a-5p;hsa-miR-24-1-5p;hsa-miR-29b-1-5p;hsa-miR-30a-3p;hsa-miR-30e-3p 11 HELLS Sponge network 3.942 0 2.623 0 0.51
12 TMCC1-AS1 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-148a-5p;hsa-miR-195-3p;hsa-miR-199a-5p;hsa-miR-24-1-5p;hsa-miR-30a-3p;hsa-miR-3607-3p;hsa-miR-450b-5p 10 HELLS Sponge network 2.298 0 2.623 0 0.51
13 HCG18 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-148a-5p;hsa-miR-193b-3p;hsa-miR-195-3p;hsa-miR-24-1-5p;hsa-miR-30a-3p;hsa-miR-30e-3p;hsa-miR-3607-3p;hsa-miR-450b-5p 11 HELLS Sponge network 1.42 0 2.623 0 0.5
14 LINC00152 hsa-let-7b-3p;hsa-let-7b-5p;hsa-miR-148a-5p;hsa-miR-193b-3p;hsa-miR-195-3p;hsa-miR-24-1-5p;hsa-miR-30a-3p;hsa-miR-30e-3p;hsa-miR-3607-3p;hsa-miR-450b-5p 10 HELLS Sponge network 2.553 0 2.623 0 0.451
15 MIR4435-1HG hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-148a-5p;hsa-miR-195-3p;hsa-miR-24-1-5p;hsa-miR-30a-3p;hsa-miR-30e-3p;hsa-miR-3607-3p;hsa-miR-450b-5p 10 HELLS Sponge network 2.541 0 2.623 0 0.441
16 RP11-727A23.5 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-195-3p;hsa-miR-199a-5p;hsa-miR-24-1-5p;hsa-miR-29b-1-5p;hsa-miR-30a-3p;hsa-miR-3607-3p;hsa-miR-450b-5p 10 HELLS Sponge network 1.435 0 2.623 0 0.44
17 RP11-540A21.2 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-148a-5p;hsa-miR-193b-3p;hsa-miR-195-3p;hsa-miR-199a-5p;hsa-miR-24-1-5p;hsa-miR-3607-3p;hsa-miR-450b-5p 10 HELLS Sponge network 1.758 0 2.623 0 0.413

Quest ID: 6390a7b597c49684ec3cfce4cef8855f