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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-429 ABAT -5.1 0.00612 0.8 0.24994 MirTarget; PITA; miRanda; miRNATAP -0.11 0.00013 NA
2 hsa-miR-429 ABCA10 -5.1 0.00612 2.44 0 mirMAP -0.16 0.00036 NA
3 hsa-miR-429 ABCA9 -5.1 0.00612 3.55 0 miRanda -0.4 0 NA
4 hsa-miR-429 ABCB1 -5.1 0.00612 2.58 0 miRanda -0.29 0 NA
5 hsa-miR-429 ABCB4 -5.1 0.00612 0.46 0.17872 miRanda -0.11 0.00086 NA
6 hsa-miR-429 ABCC9 -5.1 0.00612 3.37 0 miRanda; miRNATAP -0.38 0 NA
7 hsa-miR-205-5p ABCD2 -6.36 0.00078 3.75 0 MirTarget -0.21 0 NA
8 hsa-miR-429 ABCD2 -5.1 0.00612 3.75 0 miRanda -0.41 0 NA
9 hsa-miR-429 ABCG2 -5.1 0.00612 3.88 0 miRanda -0.48 0 NA
10 hsa-miR-429 ABCG4 -5.1 0.00612 0.48 0.33914 miRanda -0.12 0.00297 NA
11 hsa-miR-429 ABI2 -5.1 0.00612 0.71 0.57514 miRNATAP -0.11 0 NA
12 hsa-miR-429 ACADSB -5.1 0.00612 0.92 0.28522 miRanda; mirMAP; miRNATAP -0.1 0 NA
13 hsa-miR-429 ACAT1 -5.1 0.00612 0.93 0.39619 miRanda -0.1 0 NA
14 hsa-miR-429 ACHE -5.1 0.00612 1.99 0 miRanda; miRNATAP -0.33 0 NA
15 hsa-miR-429 ACOX2 -5.1 0.00612 2.11 3.0E-5 miRanda; miRNATAP -0.28 0 NA
16 hsa-miR-429 ACTC1 -5.1 0.00612 1.68 0.008 MirTarget; miRanda; miRNATAP -0.32 0 NA
17 hsa-miR-429 ACTN1 -5.1 0.00612 1.11 0.49915 miRanda -0.13 0 NA
18 hsa-miR-429 ACTN2 -5.1 0.00612 1.44 0.05422 miRanda -0.25 0 NA
19 hsa-miR-429 ACVRL1 -5.1 0.00612 1.02 0.26924 miRNATAP -0.16 0 NA
20 hsa-miR-429 ADAM11 -5.1 0.00612 1.89 0 miRNATAP -0.36 0 NA
21 hsa-miR-96-5p ADAM22 -5.62 0 1.18 0.00525 TargetScan; miRNATAP -0.18 2.0E-5 NA
22 hsa-miR-429 ADAM23 -5.1 0.00612 0.67 0.33362 miRanda -0.25 0.00018 NA
23 hsa-miR-96-5p ADAM23 -5.62 0 0.67 0.33362 TargetScan -0.23 0.00073 NA
24 hsa-miR-429 ADAMTS1 -5.1 0.00612 1.97 0.14225 miRanda -0.23 0 NA
25 hsa-miR-429 ADAMTS10 -5.1 0.00612 1.6 0.00272 miRNATAP -0.29 0 NA
26 hsa-miR-429 ADAMTS16 -5.1 0.00612 1.02 0.09926 miRanda; miRNATAP -0.24 8.0E-5 NA
27 hsa-miR-429 ADAMTS2 -5.1 0.00612 1.04 0.08495 miRNATAP -0.2 0 NA
28 hsa-miR-429 ADAMTS3 -5.1 0.00612 1.94 0 PITA; miRanda; miRNATAP -0.29 0 NA
29 hsa-miR-429 ADCY2 -5.1 0.00612 4.05 0 MirTarget; PITA; miRanda; miRNATAP -0.43 0 NA
30 hsa-miR-429 ADCY5 -5.1 0.00612 2.64 4.0E-5 miRNATAP -0.25 0 NA
31 hsa-miR-429 ADCY9 -5.1 0.00612 2 0.01002 miRanda; miRNATAP -0.24 0 NA
32 hsa-miR-429 ADCYAP1 -5.1 0.00612 2.27 0.01729 miRanda -0.41 0 NA
33 hsa-miR-429 ADH1B -5.1 0.00612 6.63 0 miRanda -0.69 0 NA
34 hsa-miR-429 ADRA2C -5.1 0.00612 1.07 0.25447 miRanda -0.13 0.00204 NA
35 hsa-miR-96-5p ADRA2C -5.62 0 1.07 0.25447 TargetScan -0.14 0.00147 NA
36 hsa-miR-96-5p AEBP2 -5.62 0 0.69 0.50292 TargetScan; miRNATAP -0.1 0 NA
37 hsa-miR-429 AFF3 -5.1 0.00612 1.97 0.00218 MirTarget; PITA; miRanda; miRNATAP -0.22 0 NA
38 hsa-miR-429 AHNAK -5.1 0.00612 2.21 0.22882 PITA; miRanda; miRNATAP -0.24 0 NA
39 hsa-miR-125b-5p AIFM1 1.12 0.591 -1.12 0.44306 miRNATAP -0.12 1.0E-5 NA
40 hsa-miR-143-5p AIFM1 1.2 0.31985 -1.12 0.44306 miRNATAP -0.13 1.0E-5 NA
41 hsa-miR-145-5p AIFM1 2.3 0.29562 -1.12 0.44306 miRNATAP -0.17 0 20332243 Artificial overexpression of miR145 by using adenoviral vectors in prostate cancer PC-3 and DU145 cells significantly downregulated BNIP3 together with the upregulation of AIF reduced cell growth and increased cell death
42 hsa-miR-199a-5p AIFM1 0.41 0.83609 -1.12 0.44306 miRanda -0.11 0.0001 NA
43 hsa-miR-96-5p AJAP1 -5.62 0 2.69 0.00028 MirTarget; TargetScan -0.42 0 NA
44 hsa-miR-429 AKAP11 -5.1 0.00612 0.96 0.37733 miRanda; miRNATAP -0.12 0 NA
45 hsa-miR-429 AKAP13 -5.1 0.00612 1.16 0.40505 miRNATAP -0.13 0 NA
46 hsa-miR-205-5p AKAP2 -6.36 0.00078 3.51 0 mirMAP -0.18 2.0E-5 NA
47 hsa-miR-429 AKAP2 -5.1 0.00612 3.51 0 PITA; miRanda; miRNATAP -0.43 0 NA
48 hsa-miR-429 AKAP5 -5.1 0.00612 0.68 0.0965 miRanda -0.14 0 NA
49 hsa-miR-429 AKAP6 -5.1 0.00612 1.81 0.00211 miRanda -0.13 0.002 NA
50 hsa-miR-429 AKNA -5.1 0.00612 1.5 0.19318 miRanda -0.11 0 NA
51 hsa-let-7a-5p AKT2 -0.26 0.93488 0.03 0.98585 TargetScan -0.2 0 NA
52 hsa-miR-106a-5p AKT3 -3.05 0.00446 3.13 0 miRNATAP -0.32 0 NA
53 hsa-miR-106b-5p AKT3 -2.25 0.23316 3.13 0 miRNATAP -0.77 0 NA
54 hsa-miR-107 AKT3 -1.8 0.19514 3.13 0 PITA; miRanda -0.75 0 NA
55 hsa-miR-142-3p AKT3 -1.81 0.40929 3.13 0 miRanda -0.18 0.00013 NA
56 hsa-miR-146b-5p AKT3 -1.03 0.6012 3.13 0 miRNAWalker2 validate -0.29 0 NA
57 hsa-miR-15a-5p AKT3 -1.8 0.23949 3.13 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.75 0 NA
58 hsa-miR-15b-5p AKT3 -2.5 0.15559 3.13 0 miRNATAP -0.81 0 NA
59 hsa-miR-16-5p AKT3 -1.82 0.36513 3.13 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.74 0 NA
60 hsa-miR-17-3p AKT3 -1.18 0.51783 3.13 0 miRNATAP -0.46 0 NA
61 hsa-miR-17-5p AKT3 -2.14 0.28935 3.13 0 TargetScan; miRNATAP -0.64 0 NA
62 hsa-miR-181a-5p AKT3 -0.96 0.65234 3.13 0 miRNATAP -0.24 0.00024 NA
63 hsa-miR-181b-5p AKT3 -1.24 0.48162 3.13 0 miRNATAP -0.37 0 NA
64 hsa-miR-181c-5p AKT3 -0.96 0.46156 3.13 0 miRNATAP -0.17 0.00212 NA
65 hsa-miR-20a-5p AKT3 -1.52 0.39552 3.13 0 miRNATAP -0.48 0 NA
66 hsa-miR-20b-5p AKT3 -3.37 0.00804 3.13 0 miRNATAP -0.17 0 NA
67 hsa-miR-29b-2-5p AKT3 -0.11 0.90799 3.13 0 mirMAP -0.14 0.03379 NA
68 hsa-miR-3065-5p AKT3 -2.76 0 3.13 0 mirMAP -0.26 0 NA
69 hsa-miR-32-3p AKT3 -2.34 0 3.13 0 mirMAP -0.54 0 NA
70 hsa-miR-320a AKT3 -0.48 0.81954 3.13 0 PITA; miRanda; miRNATAP -0.37 0 NA
71 hsa-miR-320b AKT3 -1.27 0.10979 3.13 0 PITA; miRanda; miRNATAP -0.38 0 NA
72 hsa-miR-320c AKT3 -1.08 0.00019 3.13 0 PITA; miRanda; miRNATAP -0.29 0 NA
73 hsa-miR-335-3p AKT3 -1.2 0.42815 3.13 0 mirMAP -0.44 0 NA
74 hsa-miR-33a-3p AKT3 -1.24 0.00092 3.13 0 mirMAP -0.46 0 NA
75 hsa-miR-340-5p AKT3 -1.25 0.15805 3.13 0 mirMAP -0.56 0 NA
76 hsa-miR-362-3p AKT3 -0.46 0.3668 3.13 0 miRanda -0.21 0.00314 NA
77 hsa-miR-362-5p AKT3 -0.31 0.72134 3.13 0 PITA; TargetScan; miRNATAP -0.2 0.0011 NA
78 hsa-miR-421 AKT3 -2.02 0 3.13 0 miRanda; mirMAP -0.44 0 NA
79 hsa-miR-501-3p AKT3 -2 0.14774 3.13 0 miRNATAP -0.52 0 NA
80 hsa-miR-502-3p AKT3 -0.47 0.59412 3.13 0 miRNATAP -0.2 0.00914 NA
81 hsa-miR-505-3p AKT3 -1.15 0.37434 3.13 0 mirMAP -0.49 0 22051041 We also find that Akt3 correlate inversely with miR-505 modulates drug sensitivity in MCF7-ADR
82 hsa-miR-548v AKT3 -1.35 0.0004 3.13 0 miRNATAP -0.21 0 NA
83 hsa-miR-577 AKT3 -2.96 0.00182 3.13 0 mirMAP -0.18 0 NA
84 hsa-miR-616-5p AKT3 -1.74 6.0E-5 3.13 0 mirMAP -0.34 0 NA
85 hsa-miR-769-5p AKT3 -1.42 0.17015 3.13 0 PITA; miRNATAP -0.67 0 NA
86 hsa-miR-93-5p AKT3 -2.57 0.3422 3.13 0 miRNATAP -0.67 0 NA
87 hsa-miR-429 ALDH1A1 -5.1 0.00612 2.25 0.07591 miRanda -0.27 0 NA
88 hsa-miR-429 ALDH1A3 -5.1 0.00612 1.32 0.0602 PITA; miRanda -0.14 0.00031 NA
89 hsa-miR-429 ALX1 -5.1 0.00612 0.68 0.44976 miRanda -0.23 8.0E-5 NA
90 hsa-miR-429 AMOTL2 -5.1 0.00612 1.07 0.40188 MirTarget; PITA; miRanda; miRNATAP -0.16 0 NA
91 hsa-miR-96-5p AMOTL2 -5.62 0 1.07 0.40188 TargetScan; miRNATAP -0.17 0 NA
92 hsa-miR-96-5p AMZ1 -5.62 0 1.41 0.00653 mirMAP -0.18 0 NA
93 hsa-miR-429 ANGPT1 -5.1 0.00612 1.68 2.0E-5 miRanda -0.29 0 NA
94 hsa-miR-429 ANK2 -5.1 0.00612 2.37 0.00187 miRanda; miRNATAP -0.26 0 NA
95 hsa-miR-429 ANKDD1A -5.1 0.00612 1.05 0.07805 miRanda -0.11 0 NA
96 hsa-miR-429 ANKRD12 -5.1 0.00612 0.68 0.49527 miRanda; miRNATAP -0.1 0 NA
97 hsa-miR-429 ANKRD13B -5.1 0.00612 0.92 0.20172 miRNATAP -0.15 0 NA
98 hsa-miR-429 ANKRD34A -5.1 0.00612 1.11 2.0E-5 miRanda -0.13 0 NA
99 hsa-miR-429 ANKRD40 -5.1 0.00612 0.77 0.49896 miRanda -0.13 0 NA
100 hsa-miR-429 ANKS1B -5.1 0.00612 1.94 1.0E-5 miRanda -0.17 7.0E-5 NA
101 hsa-miR-429 ANO3 -5.1 0.00612 0.9 0.26562 miRanda -0.14 0.00235 NA
102 hsa-miR-429 ANO5 -5.1 0.00612 2.28 0 miRanda -0.35 0 NA
103 hsa-miR-429 ANO6 -5.1 0.00612 1.7 0.13869 miRanda -0.23 0 NA
104 hsa-miR-429 ANTXR2 -5.1 0.00612 2.81 0.00253 miRNATAP -0.38 0 NA
105 hsa-miR-96-5p ANTXR2 -5.62 0 2.81 0.00253 TargetScan; miRNATAP -0.44 0 NA
106 hsa-miR-429 AP1S2 -5.1 0.00612 0.81 0.43185 MirTarget; PITA; miRanda; miRNATAP -0.17 0 NA
107 hsa-miR-429 AP4S1 -5.1 0.00612 0.69 0.08532 miRanda; miRNATAP -0.11 0 NA
108 hsa-miR-335-5p APAF1 -0.15 0.87942 0.05 0.95933 miRNAWalker2 validate -0.13 0 NA
109 hsa-miR-429 APBA1 -5.1 0.00612 1.5 0.00261 miRNATAP -0.19 0 NA
110 hsa-miR-429 APBB1 -5.1 0.00612 2.45 0.00532 miRNATAP -0.37 0 NA
111 hsa-miR-429 APCDD1L -5.1 0.00612 -0.72 0.27042 miRNATAP -0.15 0.0117 NA
112 hsa-miR-429 AQP4 -5.1 0.00612 1.12 0.16733 miRanda; mirMAP -0.13 0.0135 NA
113 hsa-miR-429 AR -5.1 0.00612 2.48 6.0E-5 miRNATAP -0.13 0.02306 NA
114 hsa-miR-429 ARHGAP10 -5.1 0.00612 1.48 0.05419 miRanda -0.14 0 NA
115 hsa-miR-429 ARHGAP20 -5.1 0.00612 4.61 0 MirTarget; miRanda; miRNATAP -0.52 0 NA
116 hsa-miR-429 ARHGAP24 -5.1 0.00612 1.19 0.02137 miRanda; miRNATAP -0.21 0 NA
117 hsa-miR-96-5p ARHGAP24 -5.62 0 1.19 0.02137 MirTarget; TargetScan; miRNATAP -0.21 0 NA
118 hsa-miR-429 ARHGAP25 -5.1 0.00612 1.06 0.11091 miRNATAP -0.17 0 NA
119 hsa-miR-429 ARHGAP28 -5.1 0.00612 1.47 0.00086 MirTarget -0.22 0 NA
120 hsa-miR-429 ARHGAP29 -5.1 0.00612 0.65 0.55285 miRanda -0.18 0 NA
121 hsa-miR-96-5p ARHGAP29 -5.62 0 0.65 0.55285 TargetScan -0.21 0 NA
122 hsa-miR-205-5p ARHGAP31 -6.36 0.00078 2.02 0.0044 mirMAP -0.11 0 NA
123 hsa-miR-429 ARHGAP6 -5.1 0.00612 3.79 0 MirTarget; PITA; miRanda -0.53 0 NA
124 hsa-miR-96-5p ARHGAP6 -5.62 0 3.79 0 MirTarget; TargetScan -0.56 0 NA
125 hsa-miR-429 ARHGEF10 -5.1 0.00612 1.48 0.10243 miRanda -0.21 0 NA
126 hsa-miR-429 ARHGEF17 -5.1 0.00612 1.21 0.33824 PITA; miRanda; miRNATAP -0.13 0 NA
127 hsa-miR-96-5p ARHGEF3 -5.62 0 0.98 0.42337 TargetScan -0.11 0 NA
128 hsa-miR-429 ARHGEF33 -5.1 0.00612 1.16 0.00125 miRanda -0.11 0.00033 NA
129 hsa-miR-429 ARHGEF6 -5.1 0.00612 1.94 0.00309 miRanda; mirMAP -0.27 0 NA
130 hsa-miR-429 ARID4A -5.1 0.00612 0.8 0.33399 PITA; miRanda -0.11 0 NA
131 hsa-miR-96-5p ARID4A -5.62 0 0.8 0.33399 TargetScan -0.12 0 NA
132 hsa-miR-429 ARID5B -5.1 0.00612 0.93 0.4708 miRanda; miRNATAP -0.13 0 NA
133 hsa-miR-96-5p ARID5B -5.62 0 0.93 0.4708 TargetScan; miRNATAP -0.15 0 NA
134 hsa-miR-429 ARL10 -5.1 0.00612 1.46 3.0E-5 mirMAP -0.23 0 NA
135 hsa-miR-429 ARL15 -5.1 0.00612 1.1 0.11018 MirTarget; PITA; miRanda -0.13 0 NA
136 hsa-miR-429 ARMCX1 -5.1 0.00612 2.73 0.0001 miRanda -0.38 0 NA
137 hsa-miR-429 ASAP1 -5.1 0.00612 0.26 0.81202 MirTarget; miRanda; miRNATAP -0.12 0 NA
138 hsa-miR-96-5p ASB1 -5.62 0 0.72 0.4276 mirMAP -0.1 0 NA
139 hsa-miR-96-5p ASH1L -5.62 0 0.81 0.5128 MirTarget; TargetScan; miRNATAP -0.1 0 NA
140 hsa-miR-429 ASPN -5.1 0.00612 3.19 0 miRanda -0.47 0 NA
141 hsa-miR-96-5p ASPN -5.62 0 3.19 0 TargetScan -0.51 0 NA
142 hsa-miR-96-5p ASTN1 -5.62 0 2.58 6.0E-5 TargetScan; miRNATAP -0.29 2.0E-5 NA
143 hsa-miR-429 ASXL3 -5.1 0.00612 3.36 2.0E-5 miRanda -0.48 0 NA
144 hsa-miR-429 ATF3 -5.1 0.00612 1.46 0.17757 miRanda -0.14 0.00014 NA
145 hsa-miR-429 ATL1 -5.1 0.00612 1.52 0.00298 miRanda -0.16 0 NA
146 hsa-miR-125a-3p ATM -0.85 0.18596 0.89 0.39935 miRanda -0.11 0.00094 NA
147 hsa-miR-186-5p ATM -0.84 0.64424 0.89 0.39935 mirMAP -0.13 0.00632 NA
148 hsa-miR-18a-5p ATM -3.07 0.00238 0.89 0.39935 miRNAWalker2 validate; miRTarBase; MirTarget -0.12 0 23437304; 25963391; 23857602; 23229340 MicroRNA 18a attenuates DNA damage repair through suppressing the expression of ataxia telangiectasia mutated in colorectal cancer; Through in silico search the 3'UTR of Ataxia telangiectasia mutated ATM contains a conserved miR-18a binding site; Expression of ATM was down-regulated in CRC tumors p<0.0001 and inversely correlated with miR-18a expression r = -0.4562 p<0.01; This was further confirmed by the down-regulation of ATM protein by miR-18a; As ATM is a key enzyme in DNA damage repair we evaluated the effect of miR-18a on DNA double-strand breaks; miR-18a attenuates cellular repair of DNA double-strand breaks by directly suppressing ATM a key enzyme in DNA damage repair;However the upregulation of miR-18a suppressed the level of ataxia-telangiectasia mutated and attenuated DNA double-strand break repair after irradiation which re-sensitized the cervical cancer cells to radiotherapy by promoting apoptosis;Furthermore we used antisense oligonucleotides against micro RNAs miRNA or miRNA overexpression plasmids to study the role of miR-18a and -106a on ATM expression; Furthermore we identified that ERα activates miR-18a and -106a to downregulate ATM expression; We reveal a novel mechanism involving ERα and miR-18a and -106a regulation of ATM in breast cancer;MicroRNA 18a upregulates autophagy and ataxia telangiectasia mutated gene expression in HCT116 colon cancer cells; Previous studies showed that certain microRNAs including miR-18a potentially regulate ATM in cancer cells; However the mechanisms behind the modulation of ATM by miR-18a remain to be elucidated in colon cancer cells; In the present study we explored the impact of miR-18a on the autophagy process and ATM expression in HCT116 colon cancer cells; Western blotting and luciferase assays were implemented to explore the impact of miR-18a on ATM gene expression in HCT116 cells; Moreover miR-18a overexpression led to the upregulation of ATM expression and suppression of mTORC1 activity; Results of the present study pertaining to the role of miR-18a in regulating autophagy and ATM gene expression in colon cancer cells revealed a novel function for miR-18a in a critical cellular event and on a crucial gene with significant impacts in cancer development progression treatment and in other diseases
149 hsa-miR-324-5p ATM -1.96 0.08637 0.89 0.39935 miRanda -0.16 0 NA
150 hsa-miR-339-5p ATM -1.68 0.15527 0.89 0.39935 miRanda -0.16 0 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 282 1672 1.006e-39 4.679e-36
2 CARDIOVASCULAR SYSTEM DEVELOPMENT 171 788 2.377e-37 3.686e-34
3 CIRCULATORY SYSTEM DEVELOPMENT 171 788 2.377e-37 3.686e-34
4 REGULATION OF CELL DIFFERENTIATION 251 1492 6.372e-35 7.412e-32
5 VASCULATURE DEVELOPMENT 119 469 9.815e-33 9.134e-30
6 REGULATION OF CELLULAR COMPONENT MOVEMENT 160 771 1.621e-32 1.257e-29
7 CELL DEVELOPMENT 237 1426 4.691e-32 3.118e-29
8 BLOOD VESSEL MORPHOGENESIS 101 364 2.374e-31 1.381e-28
9 BIOLOGICAL ADHESION 188 1032 2.139e-30 1.106e-27
10 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 200 1142 5.537e-30 2.576e-27
11 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 227 1395 2.735e-29 1.157e-26
12 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 252 1656 5.371e-28 2.083e-25
13 NEUROGENESIS 224 1402 9.59e-28 3.432e-25
14 REGULATION OF PHOSPHORUS METABOLIC PROCESS 246 1618 3.036e-27 1.009e-24
15 INTRACELLULAR SIGNAL TRANSDUCTION 237 1572 1.103e-25 3.421e-23
16 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 176 1021 1.539e-25 4.477e-23
17 REGULATION OF CELL PROLIFERATION 228 1496 2.47e-25 6.761e-23
18 REGULATION OF CELL DEVELOPMENT 153 836 5.776e-25 1.493e-22
19 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 202 1275 1.669e-24 4.086e-22
20 TISSUE DEVELOPMENT 228 1518 1.86e-24 4.327e-22
21 REGULATION OF SYSTEM PROCESS 109 507 1.277e-23 2.828e-21
22 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 259 1848 2.411e-23 4.882e-21
23 HEART DEVELOPMENT 103 466 2.413e-23 4.882e-21
24 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 172 1036 4.19e-23 7.799e-21
25 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 172 1036 4.19e-23 7.799e-21
26 REGULATION OF PROTEIN MODIFICATION PROCESS 242 1710 2.443e-22 4.373e-20
27 POSITIVE REGULATION OF CELL DIFFERENTIATION 145 823 4.965e-22 8.557e-20
28 MUSCLE STRUCTURE DEVELOPMENT 96 432 5.285e-22 8.783e-20
29 LOCOMOTION 177 1114 1.302e-21 2.088e-19
30 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 141 799 1.658e-21 2.572e-19
31 REGULATION OF NEURON DIFFERENTIATION 111 554 1.873e-21 2.812e-19
32 POSITIVE REGULATION OF CELL COMMUNICATION 220 1532 4.594e-21 6.68e-19
33 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 134 750 5.787e-21 8.159e-19
34 RESPONSE TO ENDOGENOUS STIMULUS 211 1450 6.802e-21 9.308e-19
35 BEHAVIOR 105 516 7.137e-21 9.488e-19
36 POSITIVE REGULATION OF MOLECULAR FUNCTION 245 1791 1.306e-20 1.651e-18
37 ANGIOGENESIS 74 293 1.313e-20 1.651e-18
38 REGULATION OF TRANSPORT 246 1804 1.635e-20 2.002e-18
39 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 162 1008 2.574e-20 3.071e-18
40 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 159 983 3.145e-20 3.659e-18
41 NEURON DIFFERENTIATION 146 874 6.214e-20 7.052e-18
42 RESPONSE TO OXYGEN CONTAINING COMPOUND 201 1381 6.519e-20 7.223e-18
43 POSITIVE REGULATION OF RESPONSE TO STIMULUS 256 1929 9.431e-20 1.02e-17
44 NEGATIVE REGULATION OF CELL COMMUNICATION 180 1192 1.531e-19 1.619e-17
45 ORGAN MORPHOGENESIS 141 841 2.033e-19 2.056e-17
46 REGULATION OF CELL DEATH 209 1472 2.024e-19 2.056e-17
47 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 154 957 2.16e-19 2.139e-17
48 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 101 513 4.815e-19 4.668e-17
49 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 135 801 7.985e-19 7.583e-17
50 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 209 1492 9.797e-19 9.118e-17
51 CELL MOTILITY 138 835 1.828e-18 1.636e-16
52 LOCALIZATION OF CELL 138 835 1.828e-18 1.636e-16
53 CENTRAL NERVOUS SYSTEM DEVELOPMENT 142 872 2.142e-18 1.881e-16
54 TISSUE MORPHOGENESIS 102 533 2.608e-18 2.247e-16
55 CELL CELL ADHESION 111 608 3.117e-18 2.637e-16
56 POSITIVE REGULATION OF CATALYTIC ACTIVITY 210 1518 3.387e-18 2.814e-16
57 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 170 1135 4.037e-18 3.295e-16
58 REGULATION OF KINASE ACTIVITY 130 776 6.184e-18 4.961e-16
59 MUSCLE SYSTEM PROCESS 68 282 6.861e-18 5.411e-16
60 REGULATION OF MAPK CASCADE 116 660 1.062e-17 8.235e-16
61 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 192 1360 1.38e-17 1.053e-15
62 CELLULAR COMPONENT MORPHOGENESIS 143 900 1.463e-17 1.098e-15
63 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 140 876 1.983e-17 1.465e-15
64 EMBRYO DEVELOPMENT 141 894 4.791e-17 3.483e-15
65 PROTEIN PHOSPHORYLATION 146 944 7.264e-17 5.2e-15
66 REGULATION OF MUSCLE SYSTEM PROCESS 53 195 1.334e-16 9.402e-15
67 REGULATION OF MEMBRANE POTENTIAL 74 343 1.742e-16 1.21e-14
68 REGULATION OF ION TRANSPORT 105 592 2.123e-16 1.453e-14
69 SINGLE ORGANISM BEHAVIOR 79 384 2.871e-16 1.936e-14
70 POSITIVE REGULATION OF GENE EXPRESSION 224 1733 6.227e-16 4.139e-14
71 REGULATION OF EPITHELIAL CELL PROLIFERATION 65 285 7.092e-16 4.648e-14
72 MODULATION OF SYNAPTIC TRANSMISSION 67 301 9.252e-16 5.979e-14
73 HEAD DEVELOPMENT 117 709 9.653e-16 6.153e-14
74 RESPONSE TO WOUNDING 100 563 1.031e-15 6.312e-14
75 REGULATION OF NEURON PROJECTION DEVELOPMENT 81 408 1.021e-15 6.312e-14
76 POSITIVE REGULATION OF CELL DEVELOPMENT 89 472 1.031e-15 6.312e-14
77 REGULATION OF BLOOD CIRCULATION 66 295 1.165e-15 7.037e-14
78 NEGATIVE REGULATION OF CELL PROLIFERATION 109 643 1.472e-15 8.784e-14
79 REGULATION OF CELL PROJECTION ORGANIZATION 99 558 1.556e-15 9.163e-14
80 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 114 689 1.899e-15 1.105e-13
81 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 84 437 2.128e-15 1.222e-13
82 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 227 1784 2.259e-15 1.282e-13
83 EPITHELIUM DEVELOPMENT 142 945 2.304e-15 1.291e-13
84 NEURON PROJECTION DEVELOPMENT 97 545 2.468e-15 1.367e-13
85 CELL CELL SIGNALING 122 767 3.8e-15 2.08e-13
86 POSITIVE REGULATION OF LOCOMOTION 81 420 5.623e-15 3.042e-13
87 TUBE DEVELOPMENT 97 552 5.691e-15 3.044e-13
88 NEURON DEVELOPMENT 112 687 9.74e-15 5.15e-13
89 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 95 541 1.147e-14 5.928e-13
90 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 95 541 1.147e-14 5.928e-13
91 NEURON PROJECTION MORPHOGENESIS 78 402 1.288e-14 6.587e-13
92 MUSCLE CELL DIFFERENTIATION 56 237 1.461e-14 7.391e-13
93 CELLULAR RESPONSE TO HORMONE STIMULUS 96 552 1.536e-14 7.685e-13
94 SYSTEM PROCESS 224 1785 1.635e-14 8.091e-13
95 POSITIVE REGULATION OF MAPK CASCADE 86 470 1.939e-14 9.499e-13
96 REGULATION OF ACTIN FILAMENT BASED PROCESS 66 312 2.075e-14 1.006e-12
97 CIRCULATORY SYSTEM PROCESS 73 366 2.126e-14 1.02e-12
98 CELLULAR RESPONSE TO NITROGEN COMPOUND 90 505 2.392e-14 1.136e-12
99 HEART MORPHOGENESIS 52 212 2.56e-14 1.203e-12
100 RESPONSE TO ORGANIC CYCLIC COMPOUND 136 917 2.664e-14 1.24e-12
101 NEGATIVE REGULATION OF CELL DIFFERENTIATION 102 609 2.772e-14 1.277e-12
102 RESPONSE TO HORMONE 133 893 3.796e-14 1.732e-12
103 REGULATION OF HEART CONTRACTION 53 221 3.894e-14 1.759e-12
104 POSITIVE REGULATION OF CELL DEATH 101 605 4.612e-14 2.063e-12
105 RESPONSE TO NITROGEN COMPOUND 129 859 5.077e-14 2.25e-12
106 REGULATION OF HOMEOSTATIC PROCESS 82 447 6.897e-14 3.028e-12
107 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 159 1152 8.312e-14 3.614e-12
108 POSITIVE REGULATION OF KINASE ACTIVITY 86 482 8.568e-14 3.691e-12
109 MORPHOGENESIS OF AN EPITHELIUM 76 400 8.879e-14 3.79e-12
110 POSITIVE REGULATION OF NEURON DIFFERENTIATION 64 306 8.99e-14 3.803e-12
111 REGULATION OF CELL ADHESION 103 629 9.093e-14 3.812e-12
112 REGULATION OF VASCULATURE DEVELOPMENT 54 233 1.012e-13 4.203e-12
113 REGULATION OF CELL MORPHOGENESIS 94 552 1.075e-13 4.429e-12
114 REGULATION OF TRANSMEMBRANE TRANSPORT 79 426 1.1e-13 4.492e-12
115 TUBE MORPHOGENESIS 66 323 1.17e-13 4.734e-12
116 REGULATION OF HYDROLASE ACTIVITY 176 1327 1.315e-13 5.252e-12
117 HOMOPHILIC CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 42 153 1.321e-13 5.252e-12
118 NEGATIVE REGULATION OF CELL DEATH 129 872 1.564e-13 6.167e-12
119 MULTICELLULAR ORGANISMAL SIGNALING 37 123 1.708e-13 6.677e-12
120 TAXIS 83 464 2.033e-13 7.882e-12
121 POSITIVE REGULATION OF HYDROLASE ACTIVITY 132 905 2.325e-13 8.942e-12
122 REGULATION OF TRANSFERASE ACTIVITY 136 946 2.964e-13 1.125e-11
123 POSITIVE REGULATION OF CELL PROLIFERATION 122 814 2.973e-13 1.125e-11
124 MESENCHYME DEVELOPMENT 47 190 3.209e-13 1.204e-11
125 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 221 1805 3.344e-13 1.237e-11
126 CELL CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 49 204 3.349e-13 1.237e-11
127 WOUND HEALING 83 470 4.18e-13 1.531e-11
128 REGULATION OF OSSIFICATION 45 178 4.465e-13 1.623e-11
129 ACTIVATION OF PROTEIN KINASE ACTIVITY 59 279 5.114e-13 1.845e-11
130 FOREBRAIN DEVELOPMENT 69 357 5.376e-13 1.915e-11
131 NEGATIVE REGULATION OF PHOSPHORYLATION 77 422 5.392e-13 1.915e-11
132 RESPONSE TO ABIOTIC STIMULUS 143 1024 6.775e-13 2.388e-11
133 CARDIAC CONDUCTION 29 82 7.299e-13 2.554e-11
134 REGULATION OF GROWTH 101 633 8.224e-13 2.856e-11
135 CELL PROJECTION ORGANIZATION 130 902 8.596e-13 2.963e-11
136 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 66 337 9.208e-13 3.15e-11
137 MUSCLE CONTRACTION 52 233 1.392e-12 4.729e-11
138 NEGATIVE REGULATION OF LOCOMOTION 56 263 1.489e-12 5.021e-11
139 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 81 465 1.693e-12 5.666e-11
140 REGULATION OF CELLULAR LOCALIZATION 167 1277 1.979e-12 6.576e-11
141 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 69 368 2.384e-12 7.868e-11
142 COGNITION 54 251 2.429e-12 7.959e-11
143 GROWTH 74 410 2.677e-12 8.711e-11
144 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 139 1004 2.796e-12 9.034e-11
145 MEMBRANE DEPOLARIZATION DURING CARDIAC MUSCLE CELL ACTION POTENTIAL 12 14 2.967e-12 9.522e-11
146 MUSCLE TISSUE DEVELOPMENT 57 275 3.023e-12 9.567e-11
147 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 81 470 3.003e-12 9.567e-11
148 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 31 98 3.564e-12 1.12e-10
149 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 84 498 3.832e-12 1.197e-10
150 RESPONSE TO EXTERNAL STIMULUS 218 1821 4.676e-12 1.451e-10
151 ACTIN FILAMENT BASED PROCESS 78 450 5.689e-12 1.753e-10
152 POSITIVE REGULATION OF TRANSPORT 131 936 5.797e-12 1.775e-10
153 EMBRYONIC MORPHOGENESIS 88 539 7.251e-12 2.205e-10
154 UROGENITAL SYSTEM DEVELOPMENT 59 299 1.081e-11 3.265e-10
155 REGULATION OF EPITHELIAL CELL MIGRATION 41 166 1.09e-11 3.273e-10
156 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 36 133 1.142e-11 3.406e-10
157 HEART PROCESS 28 85 1.31e-11 3.883e-10
158 MUSCLE ORGAN DEVELOPMENT 56 277 1.333e-11 3.925e-10
159 RESPONSE TO GROWTH FACTOR 80 475 1.363e-11 3.989e-10
160 REGULATION OF MUSCLE CONTRACTION 38 147 1.413e-11 4.108e-10
161 CHEMICAL HOMEOSTASIS 123 874 1.859e-11 5.372e-10
162 STEM CELL DIFFERENTIATION 44 190 1.994e-11 5.726e-10
163 CELL FATE COMMITMENT 49 227 2.21e-11 6.308e-10
164 REGULATION OF POSTSYNAPTIC MEMBRANE POTENTIAL 22 55 2.542e-11 7.212e-10
165 RESPONSE TO LIPID 124 888 2.584e-11 7.286e-10
166 SKELETAL SYSTEM DEVELOPMENT 77 455 2.611e-11 7.317e-10
167 CARDIAC MUSCLE CELL ACTION POTENTIAL 18 37 3.062e-11 8.531e-10
168 REGULATION OF OSTEOBLAST DIFFERENTIATION 32 112 3.342e-11 9.257e-10
169 ACTION POTENTIAL 29 94 3.517e-11 9.683e-10
170 NEGATIVE REGULATION OF TRANSPORT 77 458 3.621e-11 9.912e-10
171 REGULATION OF ION HOMEOSTASIS 45 201 3.987e-11 1.085e-09
172 DEVELOPMENTAL GROWTH 62 333 4.229e-11 1.144e-09
173 MORPHOGENESIS OF A BRANCHING STRUCTURE 40 167 5.394e-11 1.451e-09
174 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 228 1977 5.564e-11 1.488e-09
175 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 70 404 7.169e-11 1.906e-09
176 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 24 68 7.275e-11 1.923e-09
177 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 48 229 1.042e-10 2.74e-09
178 REGULATION OF METAL ION TRANSPORT 60 325 1.242e-10 3.247e-09
179 CELL PART MORPHOGENESIS 95 633 1.314e-10 3.416e-09
180 REGULATION OF CATION TRANSMEMBRANE TRANSPORT 45 208 1.333e-10 3.446e-09
181 ACTIN FILAMENT BASED MOVEMENT 28 93 1.452e-10 3.732e-09
182 CELL DEATH 133 1001 1.489e-10 3.808e-09
183 REGULATION OF MAP KINASE ACTIVITY 59 319 1.644e-10 4.18e-09
184 SYNAPSE ORGANIZATION 36 145 1.668e-10 4.219e-09
185 PHOSPHORYLATION 155 1228 1.969e-10 4.952e-09
186 CELLULAR RESPONSE TO LIPID 75 457 2.072e-10 5.183e-09
187 SECOND MESSENGER MEDIATED SIGNALING 38 160 2.118e-10 5.271e-09
188 EMBRYONIC ORGAN DEVELOPMENT 69 406 2.352e-10 5.821e-09
189 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 37 154 2.568e-10 6.323e-09
190 TELENCEPHALON DEVELOPMENT 47 228 2.944e-10 7.21e-09
191 ARTERY MORPHOGENESIS 20 51 3.12e-10 7.6e-09
192 REGULATION OF CELLULAR COMPONENT BIOGENESIS 108 767 3.263e-10 7.907e-09
193 ENDOTHELIUM DEVELOPMENT 27 90 3.374e-10 8.134e-09
194 CELL COMMUNICATION INVOLVED IN CARDIAC CONDUCTION 17 37 3.401e-10 8.157e-09
195 REGULATION OF MUSCLE TISSUE DEVELOPMENT 29 103 4.067e-10 9.705e-09
196 CARDIAC MUSCLE CELL CONTRACTION 15 29 4.545e-10 1.079e-08
197 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 56 303 4.927e-10 1.164e-08
198 ACTIN MEDIATED CELL CONTRACTION 24 74 5.42e-10 1.274e-08
199 RESPONSE TO MECHANICAL STIMULUS 44 210 6.296e-10 1.472e-08
200 REGULATION OF CELL SUBSTRATE ADHESION 39 173 6.356e-10 1.474e-08
201 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 33 131 6.366e-10 1.474e-08
202 REGULATION OF DEVELOPMENTAL GROWTH 54 289 6.644e-10 1.53e-08
203 ARTERY DEVELOPMENT 24 75 7.397e-10 1.687e-08
204 CELL CELL SIGNALING INVOLVED IN CARDIAC CONDUCTION 13 22 7.38e-10 1.687e-08
205 CELLULAR RESPONSE TO PEPTIDE 52 274 7.763e-10 1.762e-08
206 HOMEOSTATIC PROCESS 163 1337 8.833e-10 1.995e-08
207 MEMBRANE DEPOLARIZATION DURING ACTION POTENTIAL 17 39 9.414e-10 2.116e-08
208 NEURON PROJECTION GUIDANCE 43 205 9.484e-10 2.122e-08
209 CARDIAC MUSCLE TISSUE DEVELOPMENT 34 140 9.999e-10 2.226e-08
210 NEPHRON DEVELOPMENT 30 115 1.539e-09 3.395e-08
211 RENAL SYSTEM PROCESS 28 102 1.533e-09 3.395e-08
212 EXTRACELLULAR STRUCTURE ORGANIZATION 55 304 1.578e-09 3.464e-08
213 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 90 616 1.627e-09 3.553e-08
214 SPROUTING ANGIOGENESIS 18 45 1.646e-09 3.578e-08
215 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 46 232 1.712e-09 3.705e-08
216 MEMBRANE DEPOLARIZATION 21 61 1.885e-09 4.06e-08
217 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 28 103 1.954e-09 4.17e-08
218 REGULATION OF MUSCLE ORGAN DEVELOPMENT 28 103 1.954e-09 4.17e-08
219 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 83 554 2.157e-09 4.584e-08
220 METAL ION TRANSPORT 86 582 2.175e-09 4.6e-08
221 LEARNING 32 131 2.641e-09 5.56e-08
222 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 33 138 2.679e-09 5.615e-08
223 SENSORY ORGAN DEVELOPMENT 76 493 2.898e-09 6.048e-08
224 KIDNEY EPITHELIUM DEVELOPMENT 31 125 3.146e-09 6.534e-08
225 CELL ACTIVATION 84 568 3.226e-09 6.671e-08
226 REGULATION OF TRANSPORTER ACTIVITY 41 198 3.456e-09 7.116e-08
227 STRIATED MUSCLE CONTRACTION 27 99 3.5e-09 7.174e-08
228 SINGLE ORGANISM CELL ADHESION 72 459 3.574e-09 7.294e-08
229 RESPONSE TO OXYGEN LEVELS 55 311 3.688e-09 7.493e-08
230 CELLULAR CHEMICAL HOMEOSTASIS 84 570 3.817e-09 7.722e-08
231 SENSORY PERCEPTION OF PAIN 23 75 4.233e-09 8.492e-08
232 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 42 207 4.234e-09 8.492e-08
233 CELLULAR HOMEOSTASIS 95 676 4.354e-09 8.695e-08
234 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 177 1517 4.599e-09 9.145e-08
235 MESENCHYMAL CELL DIFFERENTIATION 32 134 4.815e-09 9.533e-08
236 CELL JUNCTION ORGANIZATION 39 185 4.877e-09 9.616e-08
237 REGULATION OF CYTOPLASMIC TRANSPORT 74 481 5.125e-09 1.006e-07
238 CONNECTIVE TISSUE DEVELOPMENT 40 194 6.086e-09 1.19e-07
239 MEMBRANE ASSEMBLY 13 25 6.204e-09 1.208e-07
240 REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION 41 203 7.422e-09 1.439e-07
241 DIVALENT INORGANIC CATION HOMEOSTASIS 58 343 7.715e-09 1.49e-07
242 STRIATED MUSCLE CELL DIFFERENTIATION 37 173 7.977e-09 1.534e-07
243 LOCOMOTORY BEHAVIOR 38 181 8.621e-09 1.651e-07
244 MEMBRANE BIOGENESIS 14 30 9.773e-09 1.864e-07
245 IMMUNE SYSTEM DEVELOPMENT 84 582 1.022e-08 1.94e-07
246 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 50 278 1.06e-08 2.006e-07
247 REGULATION OF INTRACELLULAR TRANSPORT 88 621 1.101e-08 2.074e-07
248 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 100 740 1.333e-08 2.501e-07
249 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 68 437 1.353e-08 2.528e-07
250 CELL MIGRATION INVOLVED IN SPROUTING ANGIOGENESIS 10 15 1.376e-08 2.542e-07
251 AMEBOIDAL TYPE CELL MIGRATION 34 154 1.374e-08 2.542e-07
252 CALCIUM ION TRANSPORT 43 223 1.375e-08 2.542e-07
253 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 44 232 1.575e-08 2.896e-07
254 ORGAN GROWTH 21 68 1.728e-08 3.165e-07
255 REGULATION OF RESPONSE TO WOUNDING 65 413 1.807e-08 3.296e-07
256 NEGATIVE REGULATION OF MOLECULAR FUNCTION 133 1079 1.842e-08 3.348e-07
257 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 34 156 1.937e-08 3.507e-07
258 SYNAPTIC SIGNALING 66 424 2.178e-08 3.929e-07
259 REGULATION OF MUSCLE ADAPTATION 20 63 2.23e-08 4.007e-07
260 REGULATION OF ENDOTHELIAL CELL MIGRATION 28 114 2.257e-08 4.039e-07
261 REGULATION OF ANATOMICAL STRUCTURE SIZE 71 472 2.681e-08 4.78e-07
262 PALLIUM DEVELOPMENT 33 153 4.076e-08 7.238e-07
263 INOSITOL LIPID MEDIATED SIGNALING 29 124 4.112e-08 7.274e-07
264 REGULATION OF BODY FLUID LEVELS 74 506 4.492e-08 7.917e-07
265 REGULATION OF RESPONSE TO STRESS 168 1468 4.576e-08 8.034e-07
266 POSITIVE REGULATION OF OSSIFICATION 23 84 4.601e-08 8.048e-07
267 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 34 162 5.205e-08 9.07e-07
268 REGULATION OF CARDIAC MUSCLE CONTRACTION 20 66 5.384e-08 9.348e-07
269 REGULATION OF SYNAPTIC PLASTICITY 31 140 5.504e-08 9.521e-07
270 REGULATION OF GTPASE ACTIVITY 91 673 5.923e-08 1.021e-06
271 REGULATION OF CELL GROWTH 61 391 6.831e-08 1.173e-06
272 CELLULAR RESPONSE TO KETONE 21 73 6.893e-08 1.179e-06
273 ION TRANSPORT 148 1262 6.985e-08 1.191e-06
274 EXTRINSIC APOPTOTIC SIGNALING PATHWAY 25 99 7.025e-08 1.193e-06
275 NEGATIVE REGULATION OF CELL DEVELOPMENT 51 303 7.131e-08 1.204e-06
276 CELL SUBSTRATE ADHESION 34 164 7.141e-08 1.204e-06
277 REGULATION OF HEART RATE 23 86 7.421e-08 1.247e-06
278 NEGATIVE REGULATION OF GROWTH 43 236 7.623e-08 1.276e-06
279 NEPHRON EPITHELIUM DEVELOPMENT 24 93 8.178e-08 1.364e-06
280 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 131 1087 8.929e-08 1.484e-06
281 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 38 197 9.321e-08 1.543e-06
282 REGULATION OF CELL JUNCTION ASSEMBLY 20 68 9.378e-08 1.547e-06
283 RESPONSE TO PEPTIDE 62 404 9.817e-08 1.614e-06
284 REGULATION OF HEART RATE BY CARDIAC CONDUCTION 13 30 9.94e-08 1.629e-06
285 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 49 289 1.016e-07 1.658e-06
286 RESPONSE TO INORGANIC SUBSTANCE 70 479 1.069e-07 1.738e-06
287 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 28 122 1.074e-07 1.741e-06
288 ION TRANSMEMBRANE TRANSPORT 105 822 1.082e-07 1.748e-06
289 CARDIAC CHAMBER DEVELOPMENT 31 144 1.088e-07 1.752e-06
290 REGULATION OF MUSCLE CELL DIFFERENTIATION 32 152 1.181e-07 1.895e-06
291 REGULATION OF PROTEIN IMPORT 36 183 1.207e-07 1.93e-06
292 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 37 191 1.223e-07 1.949e-06
293 ENDOTHELIAL CELL MIGRATION 18 57 1.228e-07 1.951e-06
294 REGULATION OF AXONOGENESIS 34 168 1.319e-07 2.088e-06
295 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 27 116 1.326e-07 2.091e-06
296 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 84 616 1.332e-07 2.094e-06
297 LEUKOCYTE DIFFERENTIATION 49 292 1.409e-07 2.207e-06
298 PATTERN SPECIFICATION PROCESS 63 418 1.512e-07 2.36e-06
299 REGULATION OF MEMBRANE DEPOLARIZATION 15 41 1.545e-07 2.405e-06
300 CARDIOCYTE DIFFERENTIATION 24 96 1.567e-07 2.431e-06
301 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 20 70 1.595e-07 2.465e-06
302 HEMOSTASIS 51 311 1.665e-07 2.565e-06
303 DIVALENT INORGANIC CATION TRANSPORT 46 268 1.715e-07 2.634e-06
304 REGULATION OF CELL MATRIX ADHESION 23 90 1.838e-07 2.813e-06
305 REGULATION OF NEURON DEATH 44 252 1.92e-07 2.929e-06
306 TISSUE MIGRATION 22 84 2.121e-07 3.225e-06
307 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 114 926 2.154e-07 3.264e-06
308 EMBRYONIC ORGAN MORPHOGENESIS 47 279 2.241e-07 3.385e-06
309 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 45 262 2.282e-07 3.425e-06
310 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 40 220 2.275e-07 3.425e-06
311 RENAL TUBULE DEVELOPMENT 21 78 2.4e-07 3.59e-06
312 RESPONSE TO CYTOKINE 93 714 2.434e-07 3.63e-06
313 REGULATION OF MUSCLE HYPERTROPHY 14 37 2.465e-07 3.665e-06
314 APOPTOTIC SIGNALING PATHWAY 48 289 2.586e-07 3.819e-06
315 REGULATION OF PROTEIN LOCALIZATION 116 950 2.578e-07 3.819e-06
316 ENDOTHELIAL CELL DIFFERENTIATION 20 72 2.651e-07 3.904e-06
317 REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 23 92 2.827e-07 4.149e-06
318 REGULATION OF STEM CELL DIFFERENTIATION 26 113 2.871e-07 4.201e-06
319 REGULATION OF SMOOTH MUSCLE CONTRACTION 18 60 2.936e-07 4.283e-06
320 REGULATION OF STRIATED MUSCLE CONTRACTION 21 79 3.035e-07 4.414e-06
321 EYE DEVELOPMENT 52 326 3.095e-07 4.487e-06
322 MUSCLE CELL DEVELOPMENT 28 128 3.121e-07 4.51e-06
323 REGULATION OF SECRETION 91 699 3.359e-07 4.84e-06
324 CELLULAR RESPONSE TO ACID CHEMICAL 34 175 3.647e-07 5.238e-06
325 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 19 67 3.687e-07 5.279e-06
326 EPITHELIAL CELL DIFFERENTIATION 70 495 3.814e-07 5.444e-06
327 RESPONSE TO ALKALOID 29 137 4.038e-07 5.746e-06
328 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 26 115 4.14e-07 5.873e-06
329 REGULATION OF NEURON APOPTOTIC PROCESS 36 192 4.162e-07 5.886e-06
330 REGULATION OF HORMONE LEVELS 68 478 4.477e-07 6.313e-06
331 BRANCHING INVOLVED IN URETERIC BUD MORPHOGENESIS 15 44 4.499e-07 6.325e-06
332 REGULATION OF CALCIUM ION TRANSPORT 38 209 4.524e-07 6.341e-06
333 TRANSMEMBRANE TRANSPORT 129 1098 4.644e-07 6.489e-06
334 ION HOMEOSTASIS 78 576 4.959e-07 6.909e-06
335 REGULATION OF ADHERENS JUNCTION ORGANIZATION 16 50 5.013e-07 6.962e-06
336 ACTIVATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 23 95 5.251e-07 7.271e-06
337 NEURAL CREST CELL DIFFERENTIATION 20 75 5.468e-07 7.55e-06
338 LYMPH VESSEL DEVELOPMENT 10 20 5.933e-07 8.167e-06
339 REGULATION OF CYTOSKELETON ORGANIZATION 70 502 6.477e-07 8.89e-06
340 CYCLIC NUCLEOTIDE METABOLIC PROCESS 17 57 6.86e-07 9.388e-06
341 POSITIVE REGULATION OF GROWTH 41 238 7.151e-07 9.757e-06
342 CARDIAC CHAMBER MORPHOGENESIS 24 104 7.685e-07 1.042e-05
343 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 24 104 7.685e-07 1.042e-05
344 CALCIUM MEDIATED SIGNALING 22 90 7.733e-07 1.043e-05
345 MESONEPHROS DEVELOPMENT 22 90 7.733e-07 1.043e-05
346 CELL MATRIX ADHESION 26 119 8.36e-07 1.121e-05
347 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 45 274 8.361e-07 1.121e-05
348 REGULATION OF NEUROTRANSMITTER TRANSPORT 18 64 8.519e-07 1.139e-05
349 CATION TRANSPORT 99 796 8.722e-07 1.163e-05
350 RESPONSE TO ACID CHEMICAL 50 319 8.867e-07 1.179e-05
351 REGULATION OF NEUROTRANSMITTER LEVELS 35 190 9.251e-07 1.226e-05
352 NEGATIVE REGULATION OF GENE EXPRESSION 164 1493 9.306e-07 1.23e-05
353 MEMORY 23 98 9.467e-07 1.241e-05
354 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 23 98 9.467e-07 1.241e-05
355 RESPONSE TO KETONE 34 182 9.434e-07 1.241e-05
356 IN UTERO EMBRYONIC DEVELOPMENT 49 311 9.741e-07 1.273e-05
357 POSITIVE REGULATION OF MAP KINASE ACTIVITY 37 207 9.821e-07 1.277e-05
358 CELL GROWTH 28 135 9.828e-07 1.277e-05
359 REGULATED EXOCYTOSIS 39 224 1.006e-06 1.304e-05
360 CARDIOBLAST DIFFERENTIATION 8 13 1.031e-06 1.328e-05
361 ACTIVATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC SIGNALING PATHWAY 8 13 1.031e-06 1.328e-05
362 NEGATIVE REGULATION OF KINASE ACTIVITY 42 250 1.045e-06 1.343e-05
363 CALCIUM ION TRANSMEMBRANE TRANSPORT 31 159 1.088e-06 1.395e-05
364 GLAND DEVELOPMENT 58 395 1.115e-06 1.425e-05
365 VASCULOGENESIS 17 59 1.177e-06 1.501e-05
366 POSITIVE REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC SIGNALING PATHWAY 9 17 1.192e-06 1.515e-05
367 MESONEPHRIC TUBULE MORPHOGENESIS 16 53 1.214e-06 1.539e-05
368 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 37 209 1.249e-06 1.58e-05
369 POSITIVE REGULATION OF ENDOCYTOSIS 25 114 1.256e-06 1.584e-05
370 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 59 406 1.274e-06 1.602e-05
371 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 38 218 1.338e-06 1.678e-05
372 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 23 100 1.381e-06 1.727e-05
373 RESPONSE TO METAL ION 51 333 1.402e-06 1.749e-05
374 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 30 153 1.426e-06 1.774e-05
375 INORGANIC ION TRANSMEMBRANE TRANSPORT 77 583 1.559e-06 1.934e-05
376 MUCOPOLYSACCHARIDE METABOLIC PROCESS 24 108 1.586e-06 1.963e-05
377 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 87 684 1.621e-06 2.001e-05
378 POSITIVE REGULATION OF PEPTIDASE ACTIVITY 30 154 1.643e-06 2.023e-05
379 NEGATIVE REGULATION OF MUSCLE CONTRACTION 10 22 1.801e-06 2.212e-05
380 RESPONSE TO STEROID HORMONE 68 497 1.847e-06 2.262e-05
381 REGULATION OF ACTIN FILAMENT BASED MOVEMENT 12 32 2.008e-06 2.452e-05
382 REGULATION OF CARDIAC MUSCLE CELL CONTRACTION 11 27 2.055e-06 2.503e-05
383 REGULATION OF CATION CHANNEL ACTIVITY 21 88 2.085e-06 2.533e-05
384 NEURON MIGRATION 24 110 2.242e-06 2.717e-05
385 REGIONALIZATION 48 311 2.274e-06 2.748e-05
386 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL 19 75 2.429e-06 2.928e-05
387 CELLULAR RESPONSE TO GLUCAGON STIMULUS 13 38 2.52e-06 3.024e-05
388 KIDNEY MORPHOGENESIS 20 82 2.522e-06 3.024e-05
389 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 16 56 2.735e-06 3.271e-05
390 PLATELET ACTIVATION 28 142 2.817e-06 3.359e-05
391 NEGATIVE REGULATION OF OSSIFICATION 18 69 2.823e-06 3.359e-05
392 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 15 50 2.845e-06 3.377e-05
393 NEURON RECOGNITION 12 33 2.936e-06 3.476e-05
394 REGULATION OF OSTEOBLAST PROLIFERATION 10 23 2.969e-06 3.506e-05
395 REGULATION OF CALCIUM MEDIATED SIGNALING 19 76 3.009e-06 3.545e-05
396 ADULT BEHAVIOR 27 135 3.179e-06 3.736e-05
397 SECRETION BY CELL 66 486 3.374e-06 3.954e-05
398 RESPONSE TO ALCOHOL 53 362 3.487e-06 4.076e-05
399 EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 13 39 3.516e-06 4.1e-05
400 REGULATION OF HORMONE SECRETION 42 262 3.627e-06 4.219e-05
401 REGULATION OF BMP SIGNALING PATHWAY 19 77 3.712e-06 4.296e-05
402 DEVELOPMENTAL CELL GROWTH 19 77 3.712e-06 4.296e-05
403 REGULATION OF NEUROTRANSMITTER SECRETION 15 51 3.748e-06 4.327e-05
404 POSITIVE REGULATION OF ION TRANSPORT 39 236 3.782e-06 4.356e-05
405 CARDIAC VENTRICLE DEVELOPMENT 23 106 4.001e-06 4.597e-05
406 CELL JUNCTION ASSEMBLY 26 129 4.141e-06 4.746e-05
407 REGULATION OF ORGANELLE ORGANIZATION 132 1178 4.255e-06 4.865e-05
408 PALATE DEVELOPMENT 20 85 4.571e-06 5.213e-05
409 NEGATIVE REGULATION OF CELL GROWTH 31 170 4.726e-06 5.368e-05
410 AMINOGLYCAN BIOSYNTHETIC PROCESS 23 107 4.733e-06 5.368e-05
411 BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 10 24 4.741e-06 5.368e-05
412 CELL CHEMOTAXIS 30 162 4.848e-06 5.462e-05
413 NEGATIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 13 40 4.846e-06 5.462e-05
414 CELL PROLIFERATION 84 672 4.862e-06 5.465e-05
415 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 36 213 5.223e-06 5.856e-05
416 CARTILAGE DEVELOPMENT 28 147 5.676e-06 6.349e-05
417 RESPONSE TO MONOAMINE 12 35 5.981e-06 6.674e-05
418 IMMUNE SYSTEM PROCESS 203 1984 6.152e-06 6.848e-05
419 MYELOID CELL DIFFERENTIATION 33 189 6.255e-06 6.946e-05
420 REGULATION OF CARDIAC CONDUCTION 17 66 6.393e-06 7.082e-05
421 CELL SUBSTRATE JUNCTION ASSEMBLY 13 41 6.603e-06 7.297e-05
422 REGULATION OF PROTEIN SECRETION 55 389 6.652e-06 7.334e-05
423 NEGATIVE REGULATION OF CELL JUNCTION ASSEMBLY 9 20 6.67e-06 7.337e-05
424 REGULATION OF ORGAN GROWTH 18 73 6.717e-06 7.372e-05
425 REGULATION OF RECEPTOR ACTIVITY 24 117 6.985e-06 7.648e-05
426 REGULATION OF ORGAN MORPHOGENESIS 39 242 7.006e-06 7.652e-05
427 OSSIFICATION 40 251 7.089e-06 7.725e-05
428 RESPONSE TO OXIDATIVE STRESS 51 352 7.145e-06 7.768e-05
429 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 16 60 7.337e-06 7.958e-05
430 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL BY SARCOPLASMIC RETICULUM 10 25 7.362e-06 7.966e-05
431 SECRETION 75 588 7.626e-06 8.233e-05
432 POSITIVE REGULATION OF SYNAPTIC TRANSMISSION 23 110 7.717e-06 8.312e-05
433 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 30 166 8.049e-06 8.65e-05
434 CELLULAR RESPONSE TO CARBOHYDRATE STIMULUS 18 74 8.249e-06 8.824e-05
435 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 18 74 8.249e-06 8.824e-05
436 NEGATIVE REGULATION OF SECRETION 34 200 8.297e-06 8.855e-05
437 REGULATION OF RESPIRATORY SYSTEM PROCESS 8 16 8.366e-06 8.867e-05
438 NEURON CELL CELL ADHESION 8 16 8.366e-06 8.867e-05
439 RETINA VASCULATURE DEVELOPMENT IN CAMERA TYPE EYE 8 16 8.366e-06 8.867e-05
440 REGULATION OF PEPTIDE SECRETION 35 209 8.65e-06 9.148e-05
441 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 14 48 8.764e-06 9.247e-05
442 POSITIVE REGULATION OF GLUCOSE TRANSPORT 13 42 8.897e-06 9.366e-05
443 MYELOID LEUKOCYTE DIFFERENTIATION 21 96 9.078e-06 9.535e-05
444 SKELETAL SYSTEM MORPHOGENESIS 34 201 9.267e-06 9.712e-05
445 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 32 184 9.348e-06 9.775e-05
446 REGULATION OF JNK CASCADE 29 159 9.422e-06 9.829e-05
447 NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS 26 135 9.836e-06 0.0001024
448 REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION 11 31 1.003e-05 0.0001042
449 ZYMOGEN ACTIVATION 23 112 1.056e-05 0.0001095
450 GLAND MORPHOGENESIS 21 97 1.076e-05 0.0001113
451 ANTERIOR POSTERIOR PATTERN SPECIFICATION 33 194 1.105e-05 0.000114
452 HEART GROWTH 10 26 1.115e-05 0.0001147
453 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 27 144 1.12e-05 0.0001151
454 PHOSPHATIDYLINOSITOL 3 PHOSPHATE BIOSYNTHETIC PROCESS 14 49 1.141e-05 0.0001165
455 REGULATION OF ERK1 AND ERK2 CASCADE 38 238 1.138e-05 0.0001165
456 REGULATION OF SMOOTH MUSCLE CELL MIGRATION 14 49 1.141e-05 0.0001165
457 SODIUM ION TRANSMEMBRANE TRANSPORT 20 90 1.149e-05 0.0001168
458 PLASMA MEMBRANE ORGANIZATION 34 203 1.153e-05 0.0001168
459 AXON EXTENSION 12 37 1.15e-05 0.0001168
460 FOREBRAIN CELL MIGRATION 16 62 1.159e-05 0.0001169
461 NEGATIVE REGULATION OF SYNAPTIC TRANSMISSION 16 62 1.159e-05 0.0001169
462 REGULATION OF BLOOD PRESSURE 30 169 1.161e-05 0.000117
463 POSITIVE REGULATION OF AXONOGENESIS 17 69 1.217e-05 0.000122
464 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 47 321 1.219e-05 0.000122
465 SYNAPSE ASSEMBLY 17 69 1.217e-05 0.000122
466 REGULATION OF PROTEIN KINASE B SIGNALING 24 121 1.273e-05 0.0001272
467 ACTIVATION OF MAPK ACTIVITY 26 137 1.294e-05 0.0001289
468 GLUCOSE HOMEOSTASIS 30 170 1.309e-05 0.0001298
469 CARBOHYDRATE HOMEOSTASIS 30 170 1.309e-05 0.0001298
470 ENSHEATHMENT OF NEURONS 20 91 1.368e-05 0.0001351
471 AXON ENSHEATHMENT 20 91 1.368e-05 0.0001351
472 CYTOSKELETON ORGANIZATION 98 838 1.4e-05 0.000138
473 POTASSIUM ION TRANSPORT 28 154 1.417e-05 0.0001391
474 CELL CYCLE ARREST 28 154 1.417e-05 0.0001391
475 ENDOCARDIAL CUSHION DEVELOPMENT 11 32 1.424e-05 0.0001395
476 REGULATION OF CARTILAGE DEVELOPMENT 16 63 1.444e-05 0.0001411
477 REGULATION OF GLUCOSE IMPORT IN RESPONSE TO INSULIN STIMULUS 8 17 1.474e-05 0.0001432
478 NEGATIVE REGULATION OF ANOIKIS 8 17 1.474e-05 0.0001432
479 ACTIVATION OF PROTEIN KINASE A ACTIVITY 8 17 1.474e-05 0.0001432
480 REGULATION OF SODIUM ION TRANSPORT 18 77 1.49e-05 0.0001441
481 REGULATION OF ACTIN FILAMENT BUNDLE ASSEMBLY 18 77 1.49e-05 0.0001441
482 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 50 352 1.514e-05 0.0001462
483 LEUKOCYTE MIGRATION 40 259 1.519e-05 0.0001464
484 REGULATION OF CHEMOTAXIS 31 180 1.566e-05 0.0001506
485 REGULATION OF SEQUESTERING OF CALCIUM ION 22 107 1.599e-05 0.0001534
486 REGULATION OF ENDOTHELIAL CELL DIFFERENTIATION 10 27 1.649e-05 0.0001576
487 REGULATION OF RYANODINE SENSITIVE CALCIUM RELEASE CHANNEL ACTIVITY 10 27 1.649e-05 0.0001576
488 RESPONSE TO CALCIUM ION 23 115 1.664e-05 0.0001587
489 REGULATION OF RESPIRATORY GASEOUS EXCHANGE BY NEUROLOGICAL SYSTEM PROCESS 7 13 1.697e-05 0.0001615
490 POSITIVE REGULATION OF MUSCLE HYPERTROPHY 9 22 1.717e-05 0.0001623
491 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC SIGNALING PATHWAY 9 22 1.717e-05 0.0001623
492 POSITIVE REGULATION OF CARDIAC MUSCLE HYPERTROPHY 9 22 1.717e-05 0.0001623
493 LIMBIC SYSTEM DEVELOPMENT 21 100 1.764e-05 0.0001665
494 NEGATIVE REGULATION OF RESPONSE TO WOUNDING 28 156 1.817e-05 0.0001711
495 PROTEIN DEPHOSPHORYLATION 32 190 1.836e-05 0.0001726
496 POSITIVE REGULATION OF BLOOD CIRCULATION 20 93 1.922e-05 0.0001803
497 LEUKOCYTE ACTIVATION 56 414 2.047e-05 0.0001916
498 SMOOTH MUSCLE CONTRACTION 13 45 2.051e-05 0.0001916
499 LONG TERM SYNAPTIC POTENTIATION 12 39 2.104e-05 0.0001958
500 POSITIVE REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 12 39 2.104e-05 0.0001958
501 POSITIVE REGULATION OF CELL ADHESION 52 376 2.18e-05 0.0002025
502 AMINOGLYCAN METABOLIC PROCESS 29 166 2.205e-05 0.0002044
503 POSITIVE REGULATION OF CYTOSKELETON ORGANIZATION 30 175 2.337e-05 0.0002162
504 MUSCLE HYPERTROPHY 10 28 2.39e-05 0.0002202
505 POSITIVE REGULATION OF PHOSPHATASE ACTIVITY 10 28 2.39e-05 0.0002202
506 TISSUE REMODELING 19 87 2.45e-05 0.0002249
507 REGULATION OF CARBOHYDRATE BIOSYNTHETIC PROCESS 19 87 2.45e-05 0.0002249
508 REGULATION OF WOUND HEALING 24 126 2.579e-05 0.0002353
509 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 23 118 2.571e-05 0.0002353
510 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 24 126 2.579e-05 0.0002353
511 REGULATION OF CARDIAC MUSCLE CONTRACTION BY CALCIUM ION SIGNALING 9 23 2.629e-05 0.0002394
512 CYCLIC NUCLEOTIDE MEDIATED SIGNALING 13 46 2.66e-05 0.0002417
513 EMBRYONIC HEART TUBE DEVELOPMENT 17 73 2.693e-05 0.0002443
514 PROTEIN LOCALIZATION TO CELL PERIPHERY 27 151 2.729e-05 0.0002469
515 RENAL WATER HOMEOSTASIS 11 34 2.738e-05 0.0002469
516 CAMP METABOLIC PROCESS 11 34 2.738e-05 0.0002469
517 RESPONSE TO CARBOHYDRATE 29 168 2.779e-05 0.0002502
518 CELLULAR RESPONSE TO OXYGEN LEVELS 26 143 2.83e-05 0.0002542
519 WNT SIGNALING PATHWAY 49 351 2.91e-05 0.0002604
520 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 25 135 2.907e-05 0.0002604
521 NEURON PROJECTION EXTENSION 14 53 3.043e-05 0.0002707
522 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 14 53 3.043e-05 0.0002707
523 CYTOSOLIC CALCIUM ION TRANSPORT 14 53 3.043e-05 0.0002707
524 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 27 152 3.081e-05 0.0002736
525 EAR DEVELOPMENT 32 195 3.13e-05 0.0002774
526 POSITIVE REGULATION OF FATTY ACID OXIDATION 7 14 3.171e-05 0.0002805
527 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 26 144 3.207e-05 0.0002832
528 REGULATION OF GLUCOSE IMPORT 15 60 3.252e-05 0.000286
529 CARDIAC MUSCLE CELL DIFFERENTIATION 17 74 3.25e-05 0.000286
530 POSITIVE REGULATION OF NEURON DEATH 16 67 3.31e-05 0.00029
531 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 16 67 3.31e-05 0.00029
532 NEGATIVE REGULATION OF CELL ADHESION 35 223 3.589e-05 0.0003139
533 NEGATIVE REGULATION OF MAPK CASCADE 26 145 3.629e-05 0.0003162
534 ADENYLATE CYCLASE MODULATING G PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY 26 145 3.629e-05 0.0003162
535 NEUROMUSCULAR PROCESS 20 97 3.667e-05 0.000319
536 JNK CASCADE 18 82 3.698e-05 0.000321
537 CEREBRAL CORTEX DEVELOPMENT 21 105 3.819e-05 0.0003309
538 REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 17 75 3.907e-05 0.0003367
539 NEGATIVE REGULATION OF NEURON DEATH 29 171 3.897e-05 0.0003367
540 MULTI ORGANISM BEHAVIOR 17 75 3.907e-05 0.0003367
541 REGULATION OF ANOIKIS 9 24 3.922e-05 0.0003374
542 REGULATION OF CARDIAC MUSCLE CONTRACTION BY REGULATION OF THE RELEASE OF SEQUESTERED CALCIUM ION 8 19 3.99e-05 0.0003426
543 REGULATION OF POTASSIUM ION TRANSMEMBRANE TRANSPORT 15 61 4.011e-05 0.0003437
544 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 95 829 4.17e-05 0.0003567
545 REGULATION OF CELLULAR RESPONSE TO STRESS 82 691 4.205e-05 0.000359
546 RESPONSE TO GLUCAGON 13 48 4.367e-05 0.0003708
547 MYOFIBRIL ASSEMBLY 13 48 4.367e-05 0.0003708
548 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORT 13 48 4.367e-05 0.0003708
549 REGULATION OF POTASSIUM ION TRANSPORT 18 83 4.389e-05 0.000372
550 SPINAL CORD DEVELOPMENT 21 106 4.424e-05 0.0003743
551 REGULATION OF MEMBRANE REPOLARIZATION 10 30 4.752e-05 0.0004013
552 CRANIAL SKELETAL SYSTEM DEVELOPMENT 14 55 4.77e-05 0.000402
553 BONE DEVELOPMENT 27 156 4.937e-05 0.0004154
554 POSITIVE REGULATION OF AXON EXTENSION 11 36 4.987e-05 0.0004189
555 ENDOCRINE SYSTEM DEVELOPMENT 23 123 5.1e-05 0.0004276
556 RESPONSE TO INTERLEUKIN 1 22 115 5.147e-05 0.0004307
557 DIGESTIVE SYSTEM DEVELOPMENT 26 148 5.209e-05 0.0004352
558 AGING 39 264 5.332e-05 0.0004446
559 REGULATION OF BINDING 41 283 5.462e-05 0.0004547
560 GLOMERULUS DEVELOPMENT 13 49 5.532e-05 0.0004597
561 CELL COMMUNICATION BY ELECTRICAL COUPLING 7 15 5.552e-05 0.0004597
562 NEGATIVE REGULATION OF SMOOTH MUSCLE CONTRACTION 7 15 5.552e-05 0.0004597
563 ACTOMYOSIN STRUCTURE ORGANIZATION 17 77 5.583e-05 0.0004614
564 PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 9 25 5.715e-05 0.0004715
565 POSITIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 20 100 5.791e-05 0.0004769
566 MUSCLE ORGAN MORPHOGENESIS 16 70 5.873e-05 0.0004828
567 OUTFLOW TRACT MORPHOGENESIS 14 56 5.917e-05 0.0004855
568 REGULATION OF PEPTIDE TRANSPORT 38 256 5.951e-05 0.0004875
569 NEGATIVE REGULATION OF NUCLEOTIDE METABOLIC PROCESS 15 63 6.007e-05 0.0004912
570 RELAXATION OF MUSCLE 8 20 6.206e-05 0.0005048
571 MELANOCYTE DIFFERENTIATION 8 20 6.206e-05 0.0005048
572 AXONAL FASCICULATION 8 20 6.206e-05 0.0005048
573 POSITIVE REGULATION OF NFAT PROTEIN IMPORT INTO NUCLEUS 6 11 6.48e-05 0.0005262
574 EMBRYONIC SKELETAL SYSTEM MORPHOGENESIS 19 93 6.494e-05 0.0005264
575 REGULATION OF SYNAPTIC VESICLE TRANSPORT 10 31 6.537e-05 0.000529
576 NEGATIVE REGULATION OF EPITHELIAL CELL DIFFERENTIATION 11 37 6.61e-05 0.000534
577 REGULATION OF PEPTIDASE ACTIVITY 52 392 6.692e-05 0.0005397
578 CELLULAR RESPONSE TO CYTOKINE STIMULUS 73 606 6.797e-05 0.0005472
579 REGULATION OF SKELETAL MUSCLE TISSUE DEVELOPMENT 13 50 6.958e-05 0.0005582
580 REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 13 50 6.958e-05 0.0005582
581 NEGATIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 16 71 7.051e-05 0.0005647
582 NEGATIVE REGULATION OF CELL CYCLE 56 433 7.226e-05 0.0005777
583 REGULATION OF PHOSPHOLIPASE ACTIVITY 15 64 7.298e-05 0.0005825
584 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 20 102 7.756e-05 0.0006179
585 RAS PROTEIN SIGNAL TRANSDUCTION 25 143 7.812e-05 0.0006203
586 NEGATIVE REGULATION OF INTRACELLULAR TRANSPORT 25 143 7.812e-05 0.0006203
587 NEUROLOGICAL SYSTEM PROCESS 131 1242 8.297e-05 0.0006576
588 MESENCHYME MORPHOGENESIS 11 38 8.666e-05 0.0006846
589 POSITIVE REGULATION OF ORGAN GROWTH 11 38 8.666e-05 0.0006846
590 NEURAL CREST CELL MIGRATION 13 51 8.692e-05 0.0006855
591 REGULATION OF CELLULAR COMPONENT SIZE 46 337 8.725e-05 0.000687
592 REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 15 65 8.825e-05 0.0006936
593 NEGATIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 10 32 8.861e-05 0.0006953
594 REGULATION OF CALCIUM ION IMPORT 20 103 8.944e-05 0.0006994
595 STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 20 103 8.944e-05 0.0006994
596 REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 35 233 8.972e-05 0.0007004
597 POSITIVE REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 29 179 9.124e-05 0.0007111
598 RESPONSE TO EPINEPHRINE 7 16 9.22e-05 0.0007174
599 NEGATIVE REGULATION OF VASCULATURE DEVELOPMENT 17 80 9.283e-05 0.0007211
600 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 72 602 9.525e-05 0.0007387
601 REPRODUCTIVE SYSTEM DEVELOPMENT 53 408 9.943e-05 0.0007698
602 HIPPOCAMPUS DEVELOPMENT 16 73 0.0001004 0.0007761
603 EXOCYTOSIS 43 310 0.0001013 0.0007814
604 REGULATION OF LIPID METABOLIC PROCESS 40 282 0.0001071 0.0008242
605 VASCULAR PROCESS IN CIRCULATORY SYSTEM 27 163 0.0001072 0.0008242
606 POSITIVE REGULATION OF PROTEIN KINASE B SIGNALING 17 81 0.0001092 0.000836
607 REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 14 59 0.0001092 0.000836
608 REGULATION OF JUN KINASE ACTIVITY 17 81 0.0001092 0.000836
609 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 30 190 0.0001125 0.0008582
610 NEGATIVE CHEMOTAXIS 11 39 0.0001124 0.0008582
611 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 22 121 0.0001135 0.0008643
612 CALCIUM DEPENDENT CELL CELL ADHESION VIA PLASMA MEMBRANE CELL ADHESION MOLECULES 9 27 0.000114 0.0008668
613 REGULATION OF CYCLIC NUCLEOTIDE METABOLIC PROCESS 26 155 0.0001154 0.0008757
614 LEUKOCYTE CELL CELL ADHESION 37 255 0.0001195 0.0009056
615 RESPONSE TO ESTROGEN 33 218 0.0001211 0.0009156
616 POSITIVE REGULATION OF GLUCOSE IMPORT IN RESPONSE TO INSULIN STIMULUS 6 12 0.0001212 0.0009156
617 LYMPHOCYTE DIFFERENTIATION 32 209 0.0001227 0.0009254
618 LYMPHOCYTE ACTIVATION 46 342 0.000124 0.0009324
619 RESPONSE TO REACTIVE OXYGEN SPECIES 30 191 0.0001239 0.0009324
620 REGULATION OF INFLAMMATORY RESPONSE 41 294 0.000129 0.0009682
621 REGULATION OF FAT CELL DIFFERENTIATION 20 106 0.0001353 0.001012
622 FAT CELL DIFFERENTIATION 20 106 0.0001353 0.001012
623 SEX DIFFERENTIATION 38 266 0.0001355 0.001012
624 PROTEIN AUTOPHOSPHORYLATION 30 192 0.0001363 0.001017
625 AORTA MORPHOGENESIS 8 22 0.0001372 0.001021
626 RETINA DEVELOPMENT IN CAMERA TYPE EYE 23 131 0.0001389 0.001033
627 CELLULAR GLUCOSE HOMEOSTASIS 16 75 0.0001409 0.001045
628 T CELL DIFFERENTIATION 22 123 0.0001456 0.001078
629 REGULATION OF ENERGY HOMEOSTASIS 7 17 0.0001464 0.001083
630 REGULATION OF NUCLEOTIDE METABOLIC PROCESS 32 211 0.0001471 0.001086
631 GLIOGENESIS 28 175 0.0001489 0.001098
632 SENSORY ORGAN MORPHOGENESIS 35 239 0.0001499 0.001104
633 POSITIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 10 34 0.0001565 0.001146
634 LONG TERM MEMORY 9 28 0.0001567 0.001146
635 REGULATION OF FATTY ACID OXIDATION 9 28 0.0001567 0.001146
636 REGULATION OF SPROUTING ANGIOGENESIS 9 28 0.0001567 0.001146
637 POSITIVE REGULATION OF RECEPTOR MEDIATED ENDOCYTOSIS 12 47 0.0001587 0.001158
638 POSITIVE REGULATION OF DEPHOSPHORYLATION 12 47 0.0001587 0.001158
639 REGULATION OF PROTEIN TARGETING 42 307 0.0001649 0.001201
640 RHYTHMIC PROCESS 41 298 0.0001735 0.001261
641 POSITIVE REGULATION OF MUSCLE CELL DIFFERENTIATION 17 84 0.0001747 0.001268
642 MULTI MULTICELLULAR ORGANISM PROCESS 32 213 0.0001756 0.001273
643 PERIPHERAL NERVOUS SYSTEM DEVELOPMENT 15 69 0.0001807 0.001307
644 PEPTIDYL TYROSINE MODIFICATION 29 186 0.0001816 0.001312
645 REGULATION OF CELLULAR PROTEIN LOCALIZATION 66 552 0.000185 0.001334
646 CARDIAC VENTRICLE MORPHOGENESIS 14 62 0.0001924 0.001381
647 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 14 62 0.0001924 0.001381
648 EMBRYONIC HEART TUBE MORPHOGENESIS 14 62 0.0001924 0.001381
649 NEGATIVE REGULATION OF CYTOPLASMIC TRANSPORT 21 117 0.000194 0.001391
650 RESPONSE TO AUDITORY STIMULUS 8 23 0.0001964 0.001403
651 REGULATION OF RESPIRATORY GASEOUS EXCHANGE 8 23 0.0001964 0.001403
652 CARDIAC SEPTUM DEVELOPMENT 17 85 0.000203 0.001449
653 REGULATION OF WNT SIGNALING PATHWAY 42 310 0.0002042 0.001455
654 PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 6 13 0.0002106 0.001493
655 LYMPH VESSEL MORPHOGENESIS 6 13 0.0002106 0.001493
656 POSITIVE REGULATION OF CARDIAC MUSCLE CELL DIFFERENTIATION 6 13 0.0002106 0.001493
657 RESPONSE TO ISCHEMIA 9 29 0.0002119 0.001498
658 POSITIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 9 29 0.0002119 0.001498
659 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 15 70 0.0002139 0.00151
660 RESPONSE TO DRUG 54 431 0.0002188 0.001542
661 NEGATIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 23 135 0.0002205 0.001552
662 POSITIVE REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 7 18 0.0002238 0.001569
663 SMOOTH MUSCLE TISSUE DEVELOPMENT 7 18 0.0002238 0.001569
664 PERICARDIUM DEVELOPMENT 7 18 0.0002238 0.001569
665 REGULATION OF HEART GROWTH 11 42 0.0002322 0.001625
666 POSITIVE REGULATION OF BINDING 22 127 0.0002345 0.001636
667 NEGATIVE REGULATION OF ION TRANSPORT 22 127 0.0002345 0.001636
668 RESPONSE TO BMP 18 94 0.0002371 0.001649
669 CELLULAR RESPONSE TO BMP STIMULUS 18 94 0.0002371 0.001649
670 CARDIAC SEPTUM MORPHOGENESIS 12 49 0.0002431 0.001688
671 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 34 236 0.0002533 0.001757
672 NEGATIVE REGULATION OF MUSCLE ORGAN DEVELOPMENT 10 36 0.0002635 0.001819
673 NEGATIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 10 36 0.0002635 0.001819
674 POSITIVE REGULATION OF GLUCOSE METABOLIC PROCESS 10 36 0.0002635 0.001819
675 DENDRITE DEVELOPMENT 16 79 0.0002659 0.001833
676 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 32 218 0.00027 0.001858
677 NEGATIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 18 95 0.000272 0.001869
678 SKELETAL MUSCLE ORGAN DEVELOPMENT 23 137 0.0002753 0.001881
679 EXPLORATION BEHAVIOR 8 24 0.0002749 0.001881
680 CARDIAC EPITHELIAL TO MESENCHYMAL TRANSITION 8 24 0.0002749 0.001881
681 REGULATION OF EXECUTION PHASE OF APOPTOSIS 8 24 0.0002749 0.001881
682 REGULATION OF DENDRITE DEVELOPMENT 21 120 0.0002788 0.001902
683 REGULATION OF NEURON MIGRATION 9 30 0.0002823 0.001912
684 POSITIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION 9 30 0.0002823 0.001912
685 OSTEOCLAST DIFFERENTIATION 9 30 0.0002823 0.001912
686 CELLULAR RESPONSE TO VASCULAR ENDOTHELIAL GROWTH FACTOR STIMULUS 9 30 0.0002823 0.001912
687 LAMELLIPODIUM ASSEMBLY 9 30 0.0002823 0.001912
688 SENSORY PERCEPTION OF MECHANICAL STIMULUS 25 155 0.0002898 0.001957
689 NEUROTRANSMITTER TRANSPORT 25 155 0.0002898 0.001957
690 CELL FATE DETERMINATION 11 43 0.0002907 0.001957
691 CHONDROITIN SULFATE PROTEOGLYCAN METABOLIC PROCESS 11 43 0.0002907 0.001957
692 EAR MORPHOGENESIS 20 112 0.0002926 0.001968
693 LIPID MODIFICATION 31 210 0.0003019 0.002027
694 POSITIVE REGULATION OF PROTEIN IMPORT 19 104 0.0003038 0.002037
695 INSULIN RECEPTOR SIGNALING PATHWAY 16 80 0.0003092 0.00207
696 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 21 121 0.0003135 0.002096
697 REGULATION OF BEHAVIOR 14 65 0.0003252 0.002171
698 REGULATION OF CARDIAC MUSCLE CELL DIFFERENTIATION 7 19 0.0003311 0.002192
699 MUSCLE CELL PROLIFERATION 7 19 0.0003311 0.002192
700 KIDNEY VASCULATURE DEVELOPMENT 7 19 0.0003311 0.002192
701 NEGATIVE REGULATION OF ACTIN FILAMENT BUNDLE ASSEMBLY 7 19 0.0003311 0.002192
702 REGULATION OF SYNAPSE ORGANIZATION 20 113 0.0003305 0.002192
703 RENAL SYSTEM VASCULATURE DEVELOPMENT 7 19 0.0003311 0.002192
704 MYOBLAST DIFFERENTIATION 10 37 0.0003366 0.002225
705 REGULATION OF CELL SHAPE 23 139 0.0003417 0.002255
706 PHOSPHATIDYLINOSITOL METABOLIC PROCESS 29 193 0.0003446 0.002256
707 VASCULAR ENDOTHELIAL GROWTH FACTOR SIGNALING PATHWAY 6 14 0.0003447 0.002256
708 OUTFLOW TRACT SEPTUM MORPHOGENESIS 6 14 0.0003447 0.002256
709 POSITIVE REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 6 14 0.0003447 0.002256
710 ANGIOGENESIS INVOLVED IN WOUND HEALING 6 14 0.0003447 0.002256
711 REGULATION OF CAMP DEPENDENT PROTEIN KINASE ACTIVITY 6 14 0.0003447 0.002256
712 PROTEOGLYCAN BIOSYNTHETIC PROCESS 13 58 0.0003488 0.00228
713 PEPTIDYL SERINE MODIFICATION 24 148 0.0003497 0.002282
714 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 21 122 0.0003519 0.002293
715 METANEPHROS DEVELOPMENT 16 81 0.0003584 0.002332
716 RESPONSE TO NICOTINE 12 51 0.0003628 0.002354
717 CELLULAR RESPONSE TO FATTY ACID 12 51 0.0003628 0.002354
718 EPITHELIAL CELL APOPTOTIC PROCESS 8 25 0.0003774 0.002446
719 REGULATION OF VASOCONSTRICTION 14 66 0.0003842 0.002486
720 REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 31 213 0.0003883 0.002509
721 REGULATION OF GLUCOSE METABOLIC PROCESS 19 106 0.0003906 0.002521
722 REGULATION OF VESICLE MEDIATED TRANSPORT 56 462 0.0003928 0.002532
723 REGULATION OF DENDRITE MORPHOGENESIS 15 74 0.0004053 0.002608
724 EPITHELIAL CELL DEVELOPMENT 28 186 0.0004191 0.00269
725 CELLULAR RESPONSE TO ALCOHOL 20 115 0.0004192 0.00269
726 RESPONSE TO TUMOR NECROSIS FACTOR 33 233 0.0004238 0.002716
727 COLLAGEN FIBRIL ORGANIZATION 10 38 0.0004259 0.002718
728 REGULATION OF ACTION POTENTIAL 10 38 0.0004259 0.002718
729 REGULATION OF RENAL SYSTEM PROCESS 10 38 0.0004259 0.002718
730 REGULATION OF PROTEIN BINDING 26 168 0.0004297 0.002739
731 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 18 99 0.00046 0.002916
732 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 18 99 0.00046 0.002916
733 LIPID PHOSPHORYLATION 18 99 0.00046 0.002916
734 POSITIVE REGULATION OF CELL SUBSTRATE ADHESION 18 99 0.00046 0.002916
735 POSITIVE REGULATION OF CARBOHYDRATE METABOLIC PROCESS 15 75 0.0004714 0.002978
736 APPENDAGE DEVELOPMENT 26 169 0.0004717 0.002978
737 LIMB DEVELOPMENT 26 169 0.0004717 0.002978
738 PARTURITION 7 20 0.000476 0.003001
739 PROTEOGLYCAN METABOLIC PROCESS 16 83 0.0004773 0.003005
740 POSITIVE REGULATION OF BMP SIGNALING PATHWAY 9 32 0.0004816 0.003008
741 PATTERNING OF BLOOD VESSELS 9 32 0.0004816 0.003008
742 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 9 32 0.0004816 0.003008
743 METANEPHRIC NEPHRON DEVELOPMENT 9 32 0.0004816 0.003008
744 ADIPOSE TISSUE DEVELOPMENT 9 32 0.0004816 0.003008
745 NEGATIVE REGULATION OF SIGNAL TRANSDUCTION IN ABSENCE OF LIGAND 9 32 0.0004816 0.003008
746 MEMBRANE ORGANIZATION 96 899 0.0004868 0.003036
747 MONOVALENT INORGANIC CATION TRANSPORT 53 435 0.0004908 0.003057
748 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 13 60 0.0004951 0.00308
749 POSITIVE REGULATION OF HOMEOSTATIC PROCESS 31 216 0.0004958 0.00308
750 POSITIVE REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION 8 26 0.0005089 0.003157
751 INTRINSIC APOPTOTIC SIGNALING PATHWAY 24 152 0.000522 0.00323
752 REGULATION OF GLUCOSE TRANSPORT 18 100 0.0005216 0.00323
753 POSITIVE REGULATION OF PHOSPHOLIPASE ACTIVITY 12 53 0.0005289 0.003251
754 SPECIFICATION OF SYMMETRY 20 117 0.0005279 0.003251
755 NEGATIVE REGULATION OF EPITHELIAL CELL MIGRATION 12 53 0.0005289 0.003251
756 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 20 117 0.0005279 0.003251
757 SKELETAL MUSCLE CELL DIFFERENTIATION 12 53 0.0005289 0.003251
758 WNT SIGNALING PATHWAY CALCIUM MODULATING PATHWAY 10 39 0.000534 0.003278
759 REGULATION OF HEAT GENERATION 6 15 0.0005375 0.003282
760 NEPHRIC DUCT DEVELOPMENT 6 15 0.0005375 0.003282
761 REGULATION OF N METHYL D ASPARTATE SELECTIVE GLUTAMATE RECEPTOR ACTIVITY 6 15 0.0005375 0.003282
762 STRIATED MUSCLE CELL PROLIFERATION 6 15 0.0005375 0.003282
763 INNER EAR MORPHOGENESIS 17 92 0.0005392 0.003288
764 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 11 46 0.0005454 0.003313
765 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 46 365 0.0005445 0.003313
766 EMBRYONIC CRANIAL SKELETON MORPHOGENESIS 11 46 0.0005454 0.003313
767 REGULATION OF SYSTEMIC ARTERIAL BLOOD PRESSURE 16 84 0.0005485 0.003323
768 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 16 84 0.0005485 0.003323
769 OSTEOBLAST DIFFERENTIATION 21 126 0.0005498 0.003326
770 REGULATION OF IMMUNE SYSTEM PROCESS 140 1403 0.0005572 0.003367
771 REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 19 109 0.0005609 0.003385
772 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 26 171 0.0005667 0.003416
773 PROTEIN LOCALIZATION TO MEMBRANE 47 376 0.0005713 0.003436
774 NEGATIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 25 162 0.000573 0.003436
775 POSITIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 25 162 0.000573 0.003436
776 SODIUM ION TRANSPORT 23 144 0.0005726 0.003436
777 REGULATION OF ENDOCYTOSIS 29 199 0.000576 0.00345
778 DEPHOSPHORYLATION 38 286 0.0005866 0.003508
779 REGULATION OF EXTENT OF CELL GROWTH 18 101 0.0005903 0.003526
780 REGULATION OF CARBOHYDRATE METABOLIC PROCESS 26 172 0.0006201 0.00369
781 POSITIVE REGULATION OF ERK1 AND ERK2 CASCADE 26 172 0.0006201 0.00369
782 G PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY COUPLED TO CYCLIC NUCLEOTIDE SECOND MESSENGER 26 172 0.0006201 0.00369
783 NEGATIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 29 200 0.0006257 0.003718
784 REGULATION OF STRIATED MUSCLE CELL DIFFERENTIATION 16 85 0.0006286 0.003731
785 TRANSMISSION OF NERVE IMPULSE 12 54 0.0006334 0.003749
786 CARDIAC MUSCLE TISSUE MORPHOGENESIS 12 54 0.0006334 0.003749
787 MAMMARY GLAND MORPHOGENESIS 10 40 0.0006638 0.003905
788 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 10 40 0.0006638 0.003905
789 DEVELOPMENTAL PIGMENTATION 10 40 0.0006638 0.003905
790 NEURON DEATH 11 47 0.0006636 0.003905
791 POSITIVE REGULATION OF NEURON APOPTOTIC PROCESS 11 47 0.0006636 0.003905
792 REGULATION OF CARDIAC MUSCLE CELL MEMBRANE REPOLARIZATION 7 21 0.0006673 0.00392
793 POSITIVE REGULATION OF HEART GROWTH 8 27 0.0006752 0.003947
794 HIPPO SIGNALING 8 27 0.0006752 0.003947
795 REGULATION OF CATENIN IMPORT INTO NUCLEUS 8 27 0.0006752 0.003947
796 CENTRAL NERVOUS SYSTEM NEURON AXONOGENESIS 8 27 0.0006752 0.003947
797 RESPONSE TO ESTRADIOL 23 146 0.0006975 0.004067
798 CELLULAR RESPONSE TO INSULIN STIMULUS 23 146 0.0006975 0.004067
799 POSITIVE REGULATION OF SECRETION 46 370 0.0007301 0.004252
800 PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROCESS 20 120 0.0007366 0.004279
801 POSITIVE REGULATION OF CHEMOTAXIS 20 120 0.0007366 0.004279
802 REGULATION OF CIRCADIAN RHYTHM 18 103 0.0007511 0.004358
803 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 12 55 0.0007546 0.004368
804 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 21 129 0.0007558 0.004368
805 REGULATION OF CAMP METABOLIC PROCESS 21 129 0.0007558 0.004368
806 CELLULAR RESPONSE TO INORGANIC SUBSTANCE 24 156 0.0007643 0.004412
807 REGULATION OF ANION TRANSPORT 22 138 0.000766 0.004416
808 POSITIVE REGULATION OF SODIUM ION TRANSPORT 9 34 0.0007839 0.004503
809 RESPONSE TO PROSTAGLANDIN 9 34 0.0007839 0.004503
810 CYCLIC NUCLEOTIDE BIOSYNTHETIC PROCESS 9 34 0.0007839 0.004503
811 CELLULAR RESPONSE TO OXIDATIVE STRESS 27 184 0.0007866 0.004513
812 REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 17 95 0.0007895 0.004524
813 RESPONSE TO AMINO ACID 19 112 0.0007919 0.004532
814 RESPIRATORY GASEOUS EXCHANGE 11 48 0.0008022 0.004566
815 NEGATIVE REGULATION OF ADHERENS JUNCTION ORGANIZATION 6 16 0.0008046 0.004566
816 LYMPHANGIOGENESIS 5 11 0.0008056 0.004566
817 REGULATION OF FEVER GENERATION 5 11 0.0008056 0.004566
818 NEGATIVE REGULATION OF STRESS FIBER ASSEMBLY 6 16 0.0008046 0.004566
819 PROTEIN LOCALIZATION TO SYNAPSE 6 16 0.0008046 0.004566
820 POSITIVE REGULATION OF OSTEOBLAST PROLIFERATION 5 11 0.0008056 0.004566
821 REGULATION OF FATTY ACID BETA OXIDATION 6 16 0.0008046 0.004566
822 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 79 724 0.0008071 0.004569
823 POSITIVE REGULATION OF JUN KINASE ACTIVITY 13 63 0.0008098 0.004578
824 NEGATIVE REGULATION OF FAT CELL DIFFERENTIATION 10 41 0.0008186 0.004617
825 AORTA DEVELOPMENT 10 41 0.0008186 0.004617
826 ADHERENS JUNCTION ORGANIZATION 14 71 0.0008348 0.004703
827 MALE SEX DIFFERENTIATION 23 148 0.0008455 0.004757
828 REGULATION OF APOPTOTIC SIGNALING PATHWAY 45 363 0.00088 0.004945
829 REGULATION OF DENDRITIC SPINE DEVELOPMENT 12 56 0.0008947 0.005022
830 RESPONSE TO IMMOBILIZATION STRESS 7 22 0.0009147 0.005109
831 ENDOCARDIAL CUSHION MORPHOGENESIS 7 22 0.0009147 0.005109
832 CENTRAL NERVOUS SYSTEM PROJECTION NEURON AXONOGENESIS 7 22 0.0009147 0.005109
833 CELLULAR RESPONSE TO INTERLEUKIN 6 7 22 0.0009147 0.005109
834 CELLULAR RESPONSE TO INTERLEUKIN 1 16 88 0.0009315 0.005191
835 REGULATION OF STEM CELL PROLIFERATION 16 88 0.0009315 0.005191
836 REGULATION OF PROTEIN ACETYLATION 13 64 0.0009463 0.005267
837 ADULT LOCOMOTORY BEHAVIOR 15 80 0.0009575 0.005323
838 NEGATIVE REGULATION OF CYCLIC NUCLEOTIDE METABOLIC PROCESS 10 42 0.001002 0.005556
839 REGULATION OF BONE REMODELING 10 42 0.001002 0.005556
840 POSITIVE REGULATION OF CATION TRANSMEMBRANE TRANSPORT 17 97 0.001007 0.005576
841 VESICLE MEDIATED TRANSPORT 124 1239 0.001028 0.00569
842 POST EMBRYONIC DEVELOPMENT 16 89 0.001057 0.00584
843 CALCIUM ION IMPORT 13 65 0.001102 0.00608
844 REGULATION OF PLASMA MEMBRANE ORGANIZATION 14 73 0.001111 0.006119
845 REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 14 73 0.001111 0.006119
846 REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 8 29 0.001138 0.006237
847 PIGMENT CELL DIFFERENTIATION 8 29 0.001138 0.006237
848 POSITIVE REGULATION OF CARTILAGE DEVELOPMENT 8 29 0.001138 0.006237
849 REGULATION OF SYNAPTIC TRANSMISSION GABAERGIC 8 29 0.001138 0.006237
850 RHO PROTEIN SIGNAL TRANSDUCTION 11 50 0.001152 0.006306
851 REGULATION OF NFAT PROTEIN IMPORT INTO NUCLEUS 6 17 0.001164 0.00634
852 CYCLIC NUCLEOTIDE CATABOLIC PROCESS 6 17 0.001164 0.00634
853 REGULATION OF PROTEIN KINASE A SIGNALING 6 17 0.001164 0.00634
854 REGULATION OF CALCINEURIN NFAT SIGNALING CASCADE 6 17 0.001164 0.00634
855 REGULATION OF GLIOGENESIS 16 90 0.001196 0.006508
856 CEREBRAL CORTEX CELL MIGRATION 10 43 0.001217 0.006617
857 NEUROMUSCULAR JUNCTION DEVELOPMENT 9 36 0.001225 0.006618
858 NEGATIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 9 36 0.001225 0.006618
859 CGMP METABOLIC PROCESS 7 23 0.001229 0.006618
860 ADRENAL GLAND DEVELOPMENT 7 23 0.001229 0.006618
861 LAMELLIPODIUM ORGANIZATION 9 36 0.001225 0.006618
862 STRIATED MUSCLE ADAPTATION 7 23 0.001229 0.006618
863 CORTICAL CYTOSKELETON ORGANIZATION 9 36 0.001225 0.006618
864 NEUROTROPHIN SIGNALING PATHWAY 7 23 0.001229 0.006618
865 MULTICELLULAR ORGANISMAL WATER HOMEOSTASIS 12 58 0.00124 0.006671
866 INTEGRIN MEDIATED SIGNALING PATHWAY 15 82 0.001246 0.006694
867 NEGATIVE REGULATION OF HORMONE SECRETION 14 74 0.001276 0.006848
868 NEURON PROJECTION EXTENSION INVOLVED IN NEURON PROJECTION GUIDANCE 5 12 0.001295 0.006892
869 AXON EXTENSION INVOLVED IN AXON GUIDANCE 5 12 0.001295 0.006892
870 HEMATOPOIETIC STEM CELL DIFFERENTIATION 5 12 0.001295 0.006892
871 REGULATION OF ENDOTHELIAL CELL DEVELOPMENT 5 12 0.001295 0.006892
872 CELLULAR RESPONSE TO EPINEPHRINE STIMULUS 5 12 0.001295 0.006892
873 REGULATION OF ESTABLISHMENT OF ENDOTHELIAL BARRIER 5 12 0.001295 0.006892
874 ACTIVATION OF TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 5 12 0.001295 0.006892
875 NEGATIVE REGULATION OF PROTEIN SECRETION 18 108 0.001326 0.007049
876 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 46 381 0.001348 0.007158
877 REGULATION OF CELL SIZE 25 172 0.001383 0.007339
878 PROTEIN OLIGOMERIZATION 51 434 0.001391 0.00737
879 REGULATION OF LIPASE ACTIVITY 15 83 0.001415 0.007492
880 METENCEPHALON DEVELOPMENT 17 100 0.001426 0.007524
881 NEGATIVE REGULATION OF INFLAMMATORY RESPONSE 17 100 0.001426 0.007524
882 PEPTIDYL TYROSINE DEPHOSPHORYLATION 17 100 0.001426 0.007524
883 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 43 351 0.00143 0.007534
884 SMOOTH MUSCLE CELL DIFFERENTIATION 8 30 0.001449 0.007586
885 CHONDROITIN SULFATE PROTEOGLYCAN BIOSYNTHETIC PROCESS 8 30 0.001449 0.007586
886 NEGATIVE REGULATION OF INTRACELLULAR STEROID HORMONE RECEPTOR SIGNALING PATHWAY 8 30 0.001449 0.007586
887 NEGATIVE REGULATION OF CELL MATRIX ADHESION 8 30 0.001449 0.007586
888 POSITIVE REGULATION OF SMOOTH MUSCLE CONTRACTION 8 30 0.001449 0.007586
889 MODULATION OF EXCITATORY POSTSYNAPTIC POTENTIAL 8 30 0.001449 0.007586
890 NEGATIVE REGULATION OF JAK STAT CASCADE 10 44 0.001469 0.007672
891 NEGATIVE REGULATION OF STAT CASCADE 10 44 0.001469 0.007672
892 POSITIVE REGULATION OF PROTEIN SECRETION 29 211 0.001473 0.007685
893 CELLULAR RESPONSE TO DRUG 13 67 0.001476 0.007692
894 SIGNAL RELEASE 25 173 0.001503 0.00782
895 NEGATIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 21 136 0.00151 0.007827
896 GLIAL CELL MIGRATION 9 37 0.001511 0.007827
897 CAMP MEDIATED SIGNALING 9 37 0.001511 0.007827
898 EYE MORPHOGENESIS 21 136 0.00151 0.007827
899 POSITIVE REGULATION OF PROTEOLYSIS 44 363 0.001566 0.008105
900 FOCAL ADHESION ASSEMBLY 7 24 0.001622 0.008292
901 NEGATIVE REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 7 24 0.001622 0.008292
902 CELLULAR RESPONSE TO PROSTAGLANDIN STIMULUS 7 24 0.001622 0.008292
903 REGULATION OF POSITIVE CHEMOTAXIS 7 24 0.001622 0.008292
904 POSITIVE REGULATION OF EPITHELIAL CELL APOPTOTIC PROCESS 7 24 0.001622 0.008292
905 REGULATION OF ODONTOGENESIS 7 24 0.001622 0.008292
906 POSITIVE REGULATION OF RECEPTOR INTERNALIZATION 7 24 0.001622 0.008292
907 CELL SUBSTRATE ADHERENS JUNCTION ASSEMBLY 7 24 0.001622 0.008292
908 REGULATION OF LIPID CATABOLIC PROCESS 11 52 0.001619 0.008292
909 POSITIVE REGULATION OF STRIATED MUSCLE CELL DIFFERENTIATION 11 52 0.001619 0.008292
910 ACTIVATION OF MAPKK ACTIVITY 11 52 0.001619 0.008292
911 CELLULAR RESPONSE TO PROSTAGLANDIN E STIMULUS 6 18 0.001634 0.008325
912 RESPONSE TO CAFFEINE 6 18 0.001634 0.008325
913 INOSITOL PHOSPHATE MEDIATED SIGNALING 6 18 0.001634 0.008325
914 FORMATION OF PRIMARY GERM LAYER 18 110 0.001643 0.008362
915 HINDBRAIN DEVELOPMENT 21 137 0.001658 0.008431
916 REGULATION OF PHOSPHATASE ACTIVITY 20 128 0.00167 0.008484
917 MULTICELLULAR ORGANISMAL RESPONSE TO STRESS 13 68 0.0017 0.008608
918 NERVE DEVELOPMENT 13 68 0.0017 0.008608
919 ADENYLATE CYCLASE INHIBITING G PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY 13 68 0.0017 0.008608
920 MULTICELLULAR ORGANISM METABOLIC PROCESS 16 93 0.001709 0.008645
921 REGULATION OF ACTIN FILAMENT LENGTH 23 156 0.001741 0.008794
922 ENDOTHELIAL CELL DEVELOPMENT 10 45 0.001762 0.008881
923 VENTRICULAR CARDIAC MUSCLE TISSUE DEVELOPMENT 10 45 0.001762 0.008881
924 HOMEOSTASIS OF NUMBER OF CELLS 25 175 0.001767 0.0089
925 CELLULAR RESPONSE TO ABIOTIC STIMULUS 34 263 0.001772 0.008912
926 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 58 514 0.001784 0.008963
927 EPHRIN RECEPTOR SIGNALING PATHWAY 15 85 0.001813 0.009099
928 MAINTENANCE OF LOCATION 21 138 0.001818 0.009116
929 CARDIAC ATRIUM DEVELOPMENT 8 31 0.001824 0.009118
930 POSITIVE REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 8 31 0.001824 0.009118
931 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 18 111 0.001824 0.009118
932 POSITIVE REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 9 38 0.001847 0.009212
933 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 9 38 0.001847 0.009212
934 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 11 53 0.001904 0.009465
935 REGULATION OF NITRIC OXIDE BIOSYNTHETIC PROCESS 11 53 0.001904 0.009465
936 NEGATIVE REGULATION OF AUTOPHAGY 11 53 0.001904 0.009465
937 POSITIVE REGULATION OF SYNAPSE ASSEMBLY 12 61 0.00196 0.009689
938 POSITIVE REGULATION OF LYASE ACTIVITY 12 61 0.00196 0.009689
939 RELAXATION OF CARDIAC MUSCLE 5 13 0.001972 0.009689
940 LIPOPROTEIN TRANSPORT 5 13 0.001972 0.009689
941 LIPOPROTEIN LOCALIZATION 5 13 0.001972 0.009689
942 POSITIVE REGULATION OF CYCLASE ACTIVITY 12 61 0.00196 0.009689
943 REGULATION OF CELL COMMUNICATION BY ELECTRICAL COUPLING 5 13 0.001972 0.009689
944 NEGATIVE REGULATION OF MONOOXYGENASE ACTIVITY 5 13 0.001972 0.009689
945 MESENCHYMAL CELL PROLIFERATION 5 13 0.001972 0.009689
946 POSITIVE REGULATION OF STEM CELL PROLIFERATION 12 61 0.00196 0.009689
947 REGULATION OF BICELLULAR TIGHT JUNCTION ASSEMBLY 5 13 0.001972 0.009689
948 REGULATION OF CELL ACTIVATION 55 484 0.001979 0.009711
949 CYTOKINE MEDIATED SIGNALING PATHWAY 52 452 0.001991 0.00976
950 PROTEIN MATURATION 34 265 0.002011 0.009851
NumGOOverlapSizeP ValueAdj. P Value
1 KINASE BINDING 108 606 5.444e-17 5.057e-14
2 RECEPTOR BINDING 192 1476 5.716e-14 2.655e-11
3 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 102 629 2.257e-13 6.988e-11
4 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 159 1199 2.321e-12 5.08e-10
5 ENZYME BINDING 211 1737 2.734e-12 5.08e-10
6 PROTEIN KINASE ACTIVITY 99 640 9.039e-12 1.4e-09
7 PASSIVE TRANSMEMBRANE TRANSPORTER ACTIVITY 78 464 2.712e-11 3.599e-09
8 MOLECULAR FUNCTION REGULATOR 170 1353 3.398e-11 3.946e-09
9 GATED CHANNEL ACTIVITY 61 325 4.301e-11 4.44e-09
10 CATION CHANNEL ACTIVITY 57 298 8.698e-11 8.081e-09
11 CYTOSKELETAL PROTEIN BINDING 115 819 1.007e-10 8.178e-09
12 GROWTH FACTOR BINDING 33 123 1.056e-10 8.178e-09
13 KINASE ACTIVITY 116 842 2.714e-10 1.939e-08
14 CALCIUM ION BINDING 100 697 5.425e-10 3.36e-08
15 RECEPTOR SIGNALING PROTEIN ACTIVITY 39 172 5.308e-10 3.36e-08
16 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 25 81 7.773e-10 4.513e-08
17 SIGNAL TRANSDUCER ACTIVITY 200 1731 8.921e-10 4.875e-08
18 VOLTAGE GATED ION CHANNEL ACTIVITY 41 190 9.498e-10 4.902e-08
19 PROTEIN DOMAIN SPECIFIC BINDING 91 624 1.449e-09 7.083e-08
20 METAL ION TRANSMEMBRANE TRANSPORTER ACTIVITY 68 417 1.914e-09 8.888e-08
21 ION CHANNEL BINDING 29 111 2.767e-09 1.224e-07
22 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 57 328 3.741e-09 1.58e-07
23 MACROMOLECULAR COMPLEX BINDING 166 1399 4.458e-09 1.801e-07
24 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 55 315 5.899e-09 2.192e-07
25 CELL ADHESION MOLECULE BINDING 39 186 5.724e-09 2.192e-07
26 CYTOKINE BINDING 25 92 1.431e-08 5.113e-07
27 PROTEIN COMPLEX BINDING 119 935 1.824e-08 6.276e-07
28 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 20 64 3.012e-08 9.995e-07
29 VOLTAGE GATED SODIUM CHANNEL ACTIVITY 11 20 4.371e-08 1.4e-06
30 CALMODULIN BINDING 36 179 6.73e-08 2.084e-06
31 ACTIN BINDING 61 393 8.235e-08 2.468e-06
32 CHANNEL REGULATOR ACTIVITY 29 131 1.472e-07 4.274e-06
33 SEQUENCE SPECIFIC DNA BINDING 125 1037 1.772e-07 4.987e-06
34 PROTEIN KINASE A BINDING 15 42 2.234e-07 6.105e-06
35 PROTEIN SERINE THREONINE KINASE ACTIVITY 65 445 3.087e-07 8.193e-06
36 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 40 226 4.732e-07 1.221e-05
37 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 19 70 7.769e-07 1.922e-05
38 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 118 992 7.861e-07 1.922e-05
39 SULFUR COMPOUND BINDING 40 234 1.192e-06 2.84e-05
40 TRANSCRIPTION FACTOR BINDING 71 524 1.574e-06 3.655e-05
41 REGULATORY REGION NUCLEIC ACID BINDING 100 818 1.677e-06 3.801e-05
42 TRANSMEMBRANE TRANSPORTER ACTIVITY 117 997 1.72e-06 3.804e-05
43 IDENTICAL PROTEIN BINDING 136 1209 2.462e-06 5.318e-05
44 INTEGRIN BINDING 23 105 3.374e-06 7.123e-05
45 CALCIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 26 128 3.562e-06 7.353e-05
46 PROTEIN KINASE A CATALYTIC SUBUNIT BINDING 8 15 4.484e-06 9.055e-05
47 PHOSPHORIC ESTER HYDROLASE ACTIVITY 53 368 5.68e-06 0.0001113
48 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 46 303 5.751e-06 0.0001113
49 TRANSFORMING GROWTH FACTOR BETA BINDING 8 16 8.366e-06 0.0001554
50 CYCLIC NUCLEOTIDE BINDING 12 36 8.351e-06 0.0001554
51 DIVALENT INORGANIC CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 30 167 9.107e-06 0.0001659
52 KINASE INHIBITOR ACTIVITY 20 89 9.616e-06 0.0001718
53 SODIUM CHANNEL ACTIVITY 12 37 1.15e-05 0.0002016
54 X1 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 13 43 1.187e-05 0.0002041
55 INORGANIC CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 68 527 1.376e-05 0.0002324
56 SODIUM CHANNEL REGULATOR ACTIVITY 11 32 1.424e-05 0.0002362
57 CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 77 622 1.694e-05 0.000276
58 HEPARIN BINDING 28 157 2.053e-05 0.0003288
59 HISTONE ACETYLTRANSFERASE BINDING 10 28 2.39e-05 0.0003764
60 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 36 228 2.45e-05 0.0003794
61 VOLTAGE GATED CATION CHANNEL ACTIVITY 25 134 2.551e-05 0.0003885
62 CAMP BINDING 9 23 2.629e-05 0.000394
63 POTASSIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 26 143 2.83e-05 0.0004174
64 KINASE REGULATOR ACTIVITY 31 186 3.04e-05 0.0004412
65 PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 30 178 3.263e-05 0.0004664
66 POTASSIUM CHANNEL ACTIVITY 23 120 3.401e-05 0.0004787
67 GLYCOSAMINOGLYCAN BINDING 33 205 3.536e-05 0.0004903
68 PROTEIN HOMODIMERIZATION ACTIVITY 85 722 4.073e-05 0.0005256
69 DOUBLE STRANDED DNA BINDING 89 764 3.994e-05 0.0005256
70 PROLINE RICH REGION BINDING 8 19 3.99e-05 0.0005256
71 PDZ DOMAIN BINDING 19 90 4.042e-05 0.0005256
72 DEATH RECEPTOR ACTIVITY 9 24 3.922e-05 0.0005256
73 PROTEIN SERINE THREONINE KINASE INHIBITOR ACTIVITY 10 30 4.752e-05 0.0006047
74 PHOSPHATIDYLINOSITOL KINASE ACTIVITY 13 51 8.692e-05 0.001091
75 HORMONE BINDING 15 65 8.825e-05 0.001093
76 CYTOKINE RECEPTOR BINDING 39 271 9.496e-05 0.001161
77 SCAFFOLD PROTEIN BINDING 12 45 0.0001008 0.001216
78 ENZYME REGULATOR ACTIVITY 105 959 0.0001047 0.001247
79 PROTEIN DIMERIZATION ACTIVITY 122 1149 0.0001104 0.001267
80 STEROID HORMONE RECEPTOR ACTIVITY 14 59 0.0001092 0.001267
81 GROWTH FACTOR RECEPTOR BINDING 23 129 0.0001092 0.001267
82 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 70 588 0.0001364 0.001545
83 TRANSMEMBRANE RECEPTOR PROTEIN PHOSPHATASE ACTIVITY 7 17 0.0001464 0.001639
84 RIBONUCLEOTIDE BINDING 183 1860 0.0001637 0.00181
85 SH3 DOMAIN BINDING 21 116 0.0001713 0.001872
86 TRANSCRIPTION FACTOR ACTIVITY DIRECT LIGAND REGULATED SEQUENCE SPECIFIC DNA BINDING 12 48 0.0001971 0.002129
87 BETA AMYLOID BINDING 10 35 0.0002042 0.00218
88 TUBULIN BINDING 38 273 0.0002323 0.002424
89 VOLTAGE GATED CALCIUM CHANNEL ACTIVITY 11 42 0.0002322 0.002424
90 PHOSPHATIDYLINOSITOL 3 KINASE BINDING 9 30 0.0002823 0.002914
91 ACTIVATING TRANSCRIPTION FACTOR BINDING 13 57 0.0002907 0.002968
92 SMAD BINDING 15 72 0.0002966 0.002995
93 PROTEASE BINDING 19 104 0.0003038 0.003035
94 ADENYL NUCLEOTIDE BINDING 151 1514 0.0003456 0.003415
95 PROTEIN TYROSINE KINASE ACTIVITY 27 176 0.0003884 0.003798
96 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II DISTAL ENHANCER SEQUENCE SPECIFIC BINDING 17 90 0.0004133 0.003999
97 CORECEPTOR ACTIVITY 10 38 0.0004259 0.004079
98 ZINC ION BINDING 119 1155 0.0004428 0.004198
99 RECEPTOR SIGNALING PROTEIN SERINE THREONINE KINASE ACTIVITY 17 92 0.0005392 0.00506
100 BETA CATENIN BINDING 16 84 0.0005485 0.005096
101 RECEPTOR ACTIVITY 161 1649 0.000586 0.00539
102 SODIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 22 136 0.0006257 0.005699
103 PROTEIN TYROSINE KINASE BINDING 12 54 0.0006334 0.005713
104 RHO GTPASE BINDING 15 78 0.0007277 0.006495
105 TRANSCRIPTION COREPRESSOR ACTIVITY 31 221 0.0007341 0.006495
106 CORE PROMOTER PROXIMAL REGION DNA BINDING 46 371 0.0007734 0.006778
107 INSULIN RECEPTOR SUBSTRATE BINDING 5 11 0.0008056 0.006995
108 FIBROBLAST GROWTH FACTOR RECEPTOR BINDING 8 28 0.0008826 0.007592
109 CYCLASE ACTIVITY 7 22 0.0009147 0.007796
110 PHOSPHATASE ACTIVITY 36 275 0.001057 0.008923
111 TRANSPORTER ACTIVITY 127 1276 0.001103 0.009231
112 SIGNALING RECEPTOR ACTIVITY 137 1393 0.001135 0.009418
113 PHOSPHORIC DIESTER HYDROLASE ACTIVITY 16 90 0.001196 0.009831
NumGOOverlapSizeP ValueAdj. P Value
1 NEURON PROJECTION 178 942 8.749e-31 5.11e-28
2 CELL PROJECTION 272 1786 2.138e-30 6.242e-28
3 NEURON PART 214 1265 6.045e-30 1.177e-27
4 SYNAPSE 149 754 6.639e-28 9.692e-26
5 MEMBRANE REGION 187 1134 9.398e-25 1.098e-22
6 POSTSYNAPSE 88 378 1.09e-21 1.061e-19
7 CELL JUNCTION 181 1151 1.371e-21 1.144e-19
8 SOMATODENDRITIC COMPARTMENT 121 650 1.656e-20 1.2e-18
9 SYNAPSE PART 116 610 1.849e-20 1.2e-18
10 INTRINSIC COMPONENT OF PLASMA MEMBRANE 227 1649 2.077e-19 1.213e-17
11 DENDRITE 93 451 5.184e-19 2.752e-17
12 MEMBRANE MICRODOMAIN 70 288 1.404e-18 6.833e-17
13 PLASMA MEMBRANE REGION 147 929 7.206e-18 3.237e-16
14 PLASMA MEMBRANE PROTEIN COMPLEX 94 510 7.075e-16 2.951e-14
15 EXCITATORY SYNAPSE 51 197 4.383e-15 1.707e-13
16 CELL PROJECTION PART 138 946 6.269e-14 2.288e-12
17 AXON 78 418 1.125e-13 3.865e-12
18 CONTRACTILE FIBER 49 211 1.295e-12 4.202e-11
19 CATION CHANNEL COMPLEX 41 167 1.34e-11 4.119e-10
20 CELL LEADING EDGE 64 350 4.574e-11 1.336e-09
21 I BAND 33 121 6.554e-11 1.823e-09
22 PLASMA MEMBRANE RAFT 27 86 1.061e-10 2.817e-09
23 CELL BODY 79 494 2.43e-10 6.17e-09
24 SYNAPTIC MEMBRANE 51 261 3.883e-10 9.448e-09
25 CELL CELL CONTACT ZONE 22 64 8.034e-10 1.877e-08
26 T TUBULE 18 45 1.646e-09 3.697e-08
27 NEURON SPINE 30 121 5.661e-09 1.225e-07
28 TRANSPORTER COMPLEX 55 321 1.17e-08 2.44e-07
29 PROTEINACEOUS EXTRACELLULAR MATRIX 59 356 1.228e-08 2.474e-07
30 SARCOLEMMA 30 125 1.277e-08 2.486e-07
31 INTERCALATED DISC 18 51 1.719e-08 3.238e-07
32 MEMBRANE PROTEIN COMPLEX 127 1020 2.188e-08 3.992e-07
33 POSTSYNAPTIC MEMBRANE 40 205 3.099e-08 5.484e-07
34 RECEPTOR COMPLEX 54 327 5.724e-08 9.831e-07
35 CELL CELL JUNCTION 60 383 7.521e-08 1.255e-06
36 VOLTAGE GATED SODIUM CHANNEL COMPLEX 9 14 1.213e-07 1.967e-06
37 AXON PART 40 219 2.007e-07 3.167e-06
38 SITE OF POLARIZED GROWTH 31 149 2.447e-07 3.761e-06
39 CELL SURFACE 97 757 2.89e-07 4.327e-06
40 EXTRACELLULAR MATRIX 63 426 3.008e-07 4.391e-06
41 CELL SUBSTRATE JUNCTION 59 398 6.556e-07 9.155e-06
42 EXTRACELLULAR MATRIX COMPONENT 27 125 6.584e-07 9.155e-06
43 INTRACELLULAR VESICLE 143 1259 7.732e-07 1.05e-05
44 PRESYNAPSE 46 283 8.548e-07 1.135e-05
45 SODIUM CHANNEL COMPLEX 9 17 1.192e-06 1.547e-05
46 CYTOPLASMIC VESICLE PART 79 601 1.378e-06 1.749e-05
47 ACTIN CYTOSKELETON 62 444 2.668e-06 3.316e-05
48 SECRETORY VESICLE 63 461 4.557e-06 5.545e-05
49 LAMELLIPODIUM 31 172 6.065e-06 7.229e-05
50 FILOPODIUM 21 94 6.403e-06 7.332e-05
51 NEURONAL POSTSYNAPTIC DENSITY 15 53 6.351e-06 7.332e-05
52 ANCHORING JUNCTION 65 489 8.139e-06 9.141e-05
53 ACTIN FILAMENT 17 70 1.494e-05 0.0001646
54 VESICLE MEMBRANE 66 512 1.892e-05 0.0002009
55 BASAL PART OF CELL 14 51 1.891e-05 0.0002009
56 MAIN AXON 15 58 2.103e-05 0.0002193
57 LEADING EDGE MEMBRANE 25 134 2.551e-05 0.0002614
58 CELL CORTEX PART 23 119 2.96e-05 0.000298
59 NEURON PROJECTION TERMINUS 24 129 3.851e-05 0.0003812
60 SARCOPLASM 16 68 4.025e-05 0.0003917
61 PRESYNAPTIC MEMBRANE 14 55 4.77e-05 0.0004566
62 ACTOMYOSIN 15 62 4.921e-05 0.0004577
63 RUFFLE 27 156 4.937e-05 0.0004577
64 CELL CORTEX 36 238 6.193e-05 0.0005651
65 CORTICAL ACTIN CYTOSKELETON 14 58 8.95e-05 0.0008041
66 CORTICAL CYTOSKELETON 17 81 0.0001092 0.0009666
67 ACTIN BASED CELL PROJECTION 29 181 0.0001116 0.0009731
68 POTASSIUM CHANNEL COMPLEX 18 90 0.0001335 0.001147
69 VOLTAGE GATED CALCIUM CHANNEL COMPLEX 11 40 0.0001445 0.001223
70 PERIKARYON 20 108 0.0001764 0.001472
71 EXOCYTIC VESICLE 24 142 0.0001845 0.001496
72 SIDE OF MEMBRANE 54 428 0.0001833 0.001496
73 CALCIUM CHANNEL COMPLEX 14 62 0.0001924 0.001539
74 EXTRINSIC COMPONENT OF MEMBRANE 36 252 0.0002006 0.001583
75 BASEMENT MEMBRANE 18 93 0.0002062 0.001605
76 VACUOLE 123 1180 0.000223 0.001714
77 APICAL PLASMA MEMBRANE 40 292 0.0002268 0.00172
78 GOLGI APPARATUS 146 1445 0.0002452 0.001836
79 CYTOPLASMIC REGION 39 287 0.0003183 0.002347
80 CYTOSKELETON 190 1967 0.0003216 0.002347
81 DENDRITIC SHAFT 10 37 0.0003366 0.002427
82 ENDOSOME 87 793 0.0003773 0.002687
83 SARCOPLASMIC RETICULUM MEMBRANE 10 38 0.0004259 0.002997
84 PHOSPHATIDYLINOSITOL 3 KINASE COMPLEX 7 20 0.000476 0.00331
85 CYTOPLASMIC SIDE OF MEMBRANE 26 170 0.0005173 0.003554
86 BASAL PLASMA MEMBRANE 9 33 0.0006178 0.004196
87 CELL PROJECTION MEMBRANE 39 298 0.0006742 0.004525
88 APICAL PART OF CELL 45 361 0.000784 0.005203
89 SECRETORY GRANULE 44 352 0.0008416 0.005522
90 PROTEIN KINASE COMPLEX 16 90 0.001196 0.00776
91 COMPLEX OF COLLAGEN TRIMERS 7 23 0.001229 0.007801
92 NEURON PROJECTION MEMBRANE 9 36 0.001225 0.007801

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04210_Apoptosis 54 89 9.695e-38 1.745e-35
2 hsa04510_Focal_adhesion 58 200 1.637e-19 1.473e-17
3 hsa04151_PI3K_AKT_signaling_pathway 73 351 2.174e-15 1.305e-13
4 hsa04010_MAPK_signaling_pathway 61 268 6.141e-15 2.764e-13
5 hsa04014_Ras_signaling_pathway 52 236 2.351e-12 8.464e-11
6 hsa04722_Neurotrophin_signaling_pathway 34 127 5.891e-11 1.767e-09
7 hsa04380_Osteoclast_differentiation 32 128 1.417e-09 3.643e-08
8 hsa04360_Axon_guidance 32 130 2.151e-09 4.84e-08
9 hsa04810_Regulation_of_actin_cytoskeleton 42 214 1.182e-08 2.364e-07
10 hsa04012_ErbB_signaling_pathway 23 87 9.365e-08 1.686e-06
11 hsa04270_Vascular_smooth_muscle_contraction 27 116 1.326e-07 2.17e-06
12 hsa04020_Calcium_signaling_pathway 35 177 1.577e-07 2.365e-06
13 hsa04310_Wnt_signaling_pathway 31 151 3.342e-07 4.627e-06
14 hsa04720_Long.term_potentiation 19 70 7.769e-07 9.989e-06
15 hsa04512_ECM.receptor_interaction 21 85 1.136e-06 1.363e-05
16 hsa04960_Aldosterone.regulated_sodium_reabsorption 14 42 1.484e-06 1.669e-05
17 hsa04370_VEGF_signaling_pathway 19 76 3.009e-06 3.186e-05
18 hsa04150_mTOR_signaling_pathway 15 52 4.897e-06 4.897e-05
19 hsa04914_Progesterone.mediated_oocyte_maturation 20 87 6.675e-06 6.323e-05
20 hsa04730_Long.term_depression 17 70 1.494e-05 0.0001345
21 hsa04660_T_cell_receptor_signaling_pathway 22 108 1.865e-05 0.0001598
22 hsa04916_Melanogenesis 21 101 2.069e-05 0.0001693
23 hsa04520_Adherens_junction 17 73 2.693e-05 0.0002108
24 hsa04650_Natural_killer_cell_mediated_cytotoxicity 25 136 3.308e-05 0.0002481
25 hsa04662_B_cell_receptor_signaling_pathway 17 75 3.907e-05 0.0002813
26 hsa04630_Jak.STAT_signaling_pathway 27 155 4.397e-05 0.0003044
27 hsa04664_Fc_epsilon_RI_signaling_pathway 17 79 7.862e-05 0.0005102
28 hsa04973_Carbohydrate_digestion_and_absorption 12 44 7.937e-05 0.0005102
29 hsa04910_Insulin_signaling_pathway 24 138 0.0001171 0.0007269
30 hsa04114_Oocyte_meiosis 21 114 0.0001328 0.0007718
31 hsa04540_Gap_junction 18 90 0.0001335 0.0007718
32 hsa00532_Glycosaminoglycan_biosynthesis_._chondroitin_sulfate 8 22 0.0001372 0.0007718
33 hsa04115_p53_signaling_pathway 15 69 0.0001807 0.0009855
34 hsa04666_Fc_gamma_R.mediated_phagocytosis 18 95 0.000272 0.00144
35 hsa04974_Protein_digestion_and_absorption 16 81 0.0003584 0.001843
36 hsa04971_Gastric_acid_secretion 15 74 0.0004053 0.002026
37 hsa04670_Leukocyte_transendothelial_migration 20 117 0.0005279 0.002568
38 hsa04062_Chemokine_signaling_pathway 28 189 0.0005446 0.002579
39 hsa04390_Hippo_signaling_pathway 24 154 0.0006331 0.002922
40 hsa04070_Phosphatidylinositol_signaling_system 15 78 0.0007277 0.003275
41 hsa04970_Salivary_secretion 16 89 0.001057 0.004639
42 hsa04912_GnRH_signaling_pathway 17 101 0.001595 0.006837
43 hsa04920_Adipocytokine_signaling_pathway 13 68 0.0017 0.007116
44 hsa04620_Toll.like_receptor_signaling_pathway 17 102 0.001781 0.007286
45 hsa04514_Cell_adhesion_molecules_.CAMs. 20 136 0.00346 0.01384
46 hsa00604_Glycosphingolipid_biosynthesis_._ganglio_series 5 15 0.004045 0.01583
47 hsa04350_TGF.beta_signaling_pathway 14 85 0.004855 0.0186
48 hsa04260_Cardiac_muscle_contraction 13 77 0.005263 0.01974
49 hsa04640_Hematopoietic_cell_lineage 13 88 0.01586 0.05827
50 hsa02010_ABC_transporters 8 44 0.01698 0.06114
51 hsa04144_Endocytosis 24 203 0.02159 0.07621
52 hsa04530_Tight_junction 17 133 0.02485 0.08513
53 hsa04340_Hedgehog_signaling_pathway 9 56 0.02507 0.08513
54 hsa04710_Circadian_rhythm_._mammal 5 23 0.02724 0.09081
55 hsa00562_Inositol_phosphate_metabolism 9 57 0.02782 0.09105
56 hsa04976_Bile_secretion 10 71 0.04261 0.1369
57 hsa00601_Glycosphingolipid_biosynthesis_._lacto_and_neolacto_series 5 26 0.04411 0.1393
58 hsa04621_NOD.like_receptor_signaling_pathway 8 59 0.07846 0.2435
59 hsa04972_Pancreatic_secretion 12 101 0.0833 0.2541
60 hsa00603_Glycosphingolipid_biosynthesis_._globo_series 3 14 0.08582 0.2575
61 hsa04320_Dorso.ventral_axis_formation 4 25 0.119 0.3512
62 hsa00534_Glycosaminoglycan_biosynthesis_._heparan_sulfate 4 26 0.1326 0.385
63 hsa00230_Purine_metabolism 16 162 0.1742 0.4978
64 hsa04964_Proximal_tubule_bicarbonate_reclamation 3 23 0.2548 0.7166
65 hsa00920_Sulfur_metabolism 2 13 0.2612 0.7233
66 hsa00565_Ether_lipid_metabolism 4 36 0.2942 0.7765
67 hsa04130_SNARE_interactions_in_vesicular_transport 4 36 0.2942 0.7765
68 hsa04622_RIG.I.like_receptor_signaling_pathway 7 71 0.2976 0.7765
69 hsa00533_Glycosaminoglycan_biosynthesis_._keratan_sulfate 2 15 0.3195 0.8215
70 hsa00770_Pantothenate_and_CoA_biosynthesis 2 16 0.3483 0.8829
71 hsa00600_Sphingolipid_metabolism 4 40 0.3652 0.9131
72 hsa00450_Selenocompound_metabolism 2 17 0.3766 0.9161
73 hsa04614_Renin.angiotensin_system 2 17 0.3766 0.9161
74 hsa00340_Histidine_metabolism 3 29 0.3833 0.9199
75 hsa00512_Mucin_type_O.Glycan_biosynthesis 3 30 0.4045 0.958
76 hsa04610_Complement_and_coagulation_cascades 6 69 0.4328 0.9932
77 hsa00310_Lysine_degradation 4 44 0.4359 0.9932
78 hsa04962_Vasopressin.regulated_water_reabsorption 4 44 0.4359 0.9932
79 hsa00514_Other_types_of_O.glycan_biosynthesis 4 46 0.4705 1
80 hsa04330_Notch_signaling_pathway 4 47 0.4874 1
81 hsa00410_beta.Alanine_metabolism 2 22 0.509 1
82 hsa04110_Cell_cycle 10 128 0.5176 1
83 hsa04672_Intestinal_immune_network_for_IgA_production 4 49 0.5207 1
84 hsa00910_Nitrogen_metabolism 2 23 0.5332 1
85 hsa00760_Nicotinate_and_nicotinamide_metabolism 2 24 0.5566 1
86 hsa00563_Glycosylphosphatidylinositol.GPI..anchor_biosynthesis 2 25 0.5791 1
87 hsa00380_Tryptophan_metabolism 3 42 0.6317 1
88 hsa00071_Fatty_acid_metabolism 3 43 0.6477 1
89 hsa00280_Valine._leucine_and_isoleucine_degradation 3 44 0.6632 1
90 hsa00591_Linoleic_acid_metabolism 2 30 0.679 1
91 hsa00650_Butanoate_metabolism 2 30 0.679 1
92 hsa00250_Alanine._aspartate_and_glutamate_metabolism 2 32 0.7132 1
93 hsa00640_Propanoate_metabolism 2 32 0.7132 1
94 hsa00564_Glycerophospholipid_metabolism 5 80 0.7405 1
95 hsa00330_Arginine_and_proline_metabolism 3 54 0.7913 1
96 hsa00980_Metabolism_of_xenobiotics_by_cytochrome_P450 4 71 0.8009 1
97 hsa04623_Cytosolic_DNA.sensing_pathway 3 56 0.8113 1
98 hsa00350_Tyrosine_metabolism 2 41 0.8312 1
99 hsa00590_Arachidonic_acid_metabolism 3 59 0.8383 1
100 hsa04145_Phagosome 9 156 0.8504 1
101 hsa04146_Peroxisome 4 79 0.8625 1
102 hsa04975_Fat_digestion_and_absorption 2 46 0.8759 1
103 hsa00830_Retinol_metabolism 3 64 0.876 1
104 hsa00520_Amino_sugar_and_nucleotide_sugar_metabolism 2 48 0.8905 1
105 hsa03320_PPAR_signaling_pathway 3 70 0.9107 1
106 hsa04120_Ubiquitin_mediated_proteolysis 7 139 0.9135 1
107 hsa00983_Drug_metabolism_._other_enzymes 2 52 0.9151 1
108 hsa00982_Drug_metabolism_._cytochrome_P450 3 73 0.9245 1
109 hsa00140_Steroid_hormone_biosynthesis 2 57 0.9385 1
110 hsa03015_mRNA_surveillance_pathway 3 83 0.9576 1
111 hsa04142_Lysosome 5 121 0.9589 1
112 hsa00010_Glycolysis_._Gluconeogenesis 2 65 0.9637 1
113 hsa03018_RNA_degradation 2 71 0.9757 1
114 hsa04141_Protein_processing_in_endoplasmic_reticulum 6 168 0.9904 1
115 hsa00240_Pyrimidine_metabolism 2 99 0.9965 1
116 hsa03013_RNA_transport 2 152 0.9999 1
117 hsa04740_Olfactory_transduction 7 388 1 1

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1

MAGI2-AS3

 hsa-miR-106b-5p;hsa-miR-107;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-32-3p;hsa-miR-320a;hsa-miR-320b;hsa-miR-320c;hsa-miR-33a-3p;hsa-miR-505-3p;hsa-miR-616-5p;hsa-miR-769-5p 13 AKT3 Sponge network 3.12 0.15564 3.127 0 0.642
2

HAND2-AS1

 hsa-miR-106b-5p;hsa-miR-107;hsa-miR-146b-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-320b;hsa-miR-421;hsa-miR-616-5p;hsa-miR-93-5p 13 AKT3 Sponge network 3.513 0.20986 3.127 0 0.459
3

MAGI2-AS3

 hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7d-3p;hsa-let-7f-1-3p;hsa-miR-16-2-3p;hsa-miR-30d-3p;hsa-miR-30e-3p;hsa-miR-32-3p;hsa-miR-339-5p;hsa-miR-590-3p;hsa-miR-616-5p;hsa-miR-7-1-3p 12 PRKACB Sponge network 3.12 0.15564 1.293 0.1881 0.42
4

HAND2-AS1

 hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-324-3p;hsa-miR-330-3p;hsa-miR-486-5p;hsa-miR-584-5p;hsa-miR-629-3p;hsa-miR-93-5p 17 PIK3R1 Sponge network 3.513 0.20986 0.873 0.55556 0.374
5 PLAC4 hsa-miR-103a-3p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-338-5p;hsa-miR-93-5p 10 PIK3R1 Sponge network -1.27 0.01584 0.873 0.55556 0.347
6

RP1-60O19.1

 hsa-miR-16-1-3p;hsa-miR-16-2-3p;hsa-miR-186-5p;hsa-miR-20a-3p;hsa-miR-25-3p;hsa-miR-3200-3p;hsa-miR-320a;hsa-miR-320b;hsa-miR-320c;hsa-miR-33a-5p;hsa-miR-361-5p;hsa-miR-590-3p;hsa-miR-9-3p;hsa-miR-92a-3p 14 IRAK3 Sponge network 2.245 0.61454 1.679 0.00047 0.328
7

RP11-166D19.1

 hsa-miR-142-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-186-5p;hsa-miR-192-5p;hsa-miR-215-5p;hsa-miR-32-3p;hsa-miR-33b-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-616-5p;hsa-miR-629-5p 14 BCL2 Sponge network 3.198 0.02971 2.118 0.01827 0.324
8

USP3-AS1

 hsa-miR-103a-3p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network 1.963 0.35846 0.873 0.55556 0.303
9

RP11-161M6.2

 hsa-miR-107;hsa-miR-15b-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-20a-5p;hsa-miR-335-3p;hsa-miR-769-5p;hsa-miR-93-5p 10 AKT3 Sponge network -0.249 0.92288 3.127 0 0.278
10

ZNF883

 hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7d-3p;hsa-let-7f-1-3p;hsa-miR-16-2-3p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-194-3p;hsa-miR-2110;hsa-miR-590-5p;hsa-miR-616-5p 11 PRKACB Sponge network 1.193 0.02877 1.293 0.1881 0.272
11

MAGI2-AS3

 hsa-miR-107;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-186-5p;hsa-miR-25-3p;hsa-miR-32-3p;hsa-miR-320a;hsa-miR-320b;hsa-miR-320c;hsa-miR-590-3p;hsa-miR-616-5p 11 PRKAR1A Sponge network 3.12 0.15564 0.925 0.56412 0.267
12

LINC00473

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-20a-5p;hsa-miR-320a;hsa-miR-320c;hsa-miR-335-3p;hsa-miR-616-5p;hsa-miR-93-5p 14 AKT3 Sponge network 4.437 0.48333 3.127 0 0.265
13

MAGI2-AS3

 hsa-miR-15a-5p;hsa-miR-15b-3p;hsa-miR-15b-5p;hsa-miR-16-1-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-186-5p;hsa-miR-32-3p;hsa-miR-33b-5p;hsa-miR-590-3p;hsa-miR-616-5p;hsa-miR-629-5p;hsa-miR-7-1-3p 13 BCL2 Sponge network 3.12 0.15564 2.118 0.01827 0.262

Quest ID: 8218cd989692f5b4b040a22623a6f0af