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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-27a-3p A1CF -0.37 0.00876 -0.98 1.0E-5 MirTarget -0.55 0 NA
2 hsa-miR-148a-3p A4GNT -0.75 0 -1.24 0.00042 MirTarget -0.73 0 NA
3 hsa-miR-22-3p A4GNT -0.63 0 -1.24 0.00042 MirTarget -0.76 0 NA
4 hsa-miR-140-5p AACS -0.22 0.01407 0.96 0 miRanda -0.23 0.00433 NA
5 hsa-miR-106b-5p AADAC 0.65 0 -1.53 0 MirTarget -0.77 0 NA
6 hsa-miR-17-5p AADAC 0.7 2.0E-5 -1.53 0 MirTarget -0.19 0.04679 NA
7 hsa-miR-93-5p AADAC 1.4 0 -1.53 0 MirTarget -0.44 6.0E-5 NA
8 hsa-miR-103a-3p AADAT 0.77 0 -3.7 0 miRNAWalker2 validate -1.02 0 NA
9 hsa-miR-27b-3p AAGAB -0.82 0 0.45 0 MirTarget -0.13 0 NA
10 hsa-miR-17-5p AAK1 0.7 2.0E-5 0.62 0 TargetScan -0.11 0.0001 NA
11 hsa-miR-146b-5p AASS 0.42 0.04574 -1.86 0 miRanda -0.17 0.01702 NA
12 hsa-miR-10b-5p ABAT 2.87 0 -2.16 0 mirMAP -0.16 9.0E-5 NA
13 hsa-miR-200b-3p ABAT -1.29 0.00027 -2.16 0 MirTarget; TargetScan -0.2 0 NA
14 hsa-miR-27a-3p ABAT -0.37 0.00876 -2.16 0 MirTarget -0.5 0 NA
15 hsa-miR-429 ABAT -1.4 7.0E-5 -2.16 0 MirTarget; PITA; miRanda; miRNATAP -0.2 0 NA
16 hsa-miR-106b-5p ABCA1 0.65 0 -1.1 0 MirTarget; miRNATAP -0.19 0.00194 NA
17 hsa-miR-27a-3p ABCA1 -0.37 0.00876 -1.1 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.15 0.00176 NA
18 hsa-miR-93-5p ABCA1 1.4 0 -1.1 0 MirTarget; miRNATAP -0.2 5.0E-5 NA
19 hsa-miR-455-5p ABCA4 -0.27 0.05813 0.73 0.00376 miRanda -0.22 0.01277 NA
20 hsa-miR-429 ABCB1 -1.4 7.0E-5 -0.9 0.00459 miRanda -0.21 0 NA
21 hsa-miR-429 ABCB11 -1.4 7.0E-5 -2.63 0 miRanda -0.37 0 NA
22 hsa-miR-429 ABCB4 -1.4 7.0E-5 -1.52 0 miRanda -0.33 0 NA
23 hsa-miR-26b-5p ABCC4 -1.11 0 0.96 0.00126 MirTarget; miRNATAP -0.46 0.00011 NA
24 hsa-miR-30c-1-3p ABCC4 -1.39 0 0.96 0.00126 MirTarget -0.21 0.01565 NA
25 hsa-miR-429 ABCC6P1 -1.4 7.0E-5 -0.64 0.01293 miRanda -0.1 0.00478 NA
26 hsa-miR-429 ABCC9 -1.4 7.0E-5 -2.33 0 miRanda; miRNATAP -0.25 0 NA
27 hsa-miR-26b-5p ABCD1 -1.11 0 0.81 0 miRNAWalker2 validate -0.26 0 NA
28 hsa-miR-455-5p ABCE1 -0.27 0.05813 -0.37 0 miRanda -0.1 0.00012 NA
29 hsa-miR-429 ABCG2 -1.4 7.0E-5 -1.71 0 miRanda -0.22 0 NA
30 hsa-miR-103a-3p ABHD13 0.77 0 -0.68 0 MirTarget -0.15 0.00018 NA
31 hsa-miR-25-3p ABHD13 0.63 0 -0.68 0 miRNATAP -0.14 0.00082 NA
32 hsa-miR-106b-5p ABHD2 0.65 0 -1.2 0 miRNATAP -0.46 0 NA
33 hsa-miR-10b-5p ABHD2 2.87 0 -1.2 0 mirMAP -0.11 1.0E-5 NA
34 hsa-miR-17-5p ABHD2 0.7 2.0E-5 -1.2 0 TargetScan; miRNATAP -0.33 0 NA
35 hsa-miR-20a-5p ABHD2 0.85 0 -1.2 0 miRNATAP -0.28 0 NA
36 hsa-miR-224-5p ABHD2 2.67 0 -1.2 0 mirMAP -0.12 0 NA
37 hsa-miR-30d-5p ABHD2 0.72 0 -1.2 0 mirMAP -0.17 0.00447 NA
38 hsa-miR-93-5p ABHD2 1.4 0 -1.2 0 miRNATAP -0.47 0 NA
39 hsa-miR-106b-5p ABHD5 0.65 0 -0.6 0 MirTarget -0.19 1.0E-5 NA
40 hsa-miR-17-5p ABHD5 0.7 2.0E-5 -0.6 0 MirTarget; TargetScan -0.15 0 NA
41 hsa-miR-20a-5p ABHD5 0.85 0 -0.6 0 MirTarget -0.12 1.0E-5 NA
42 hsa-miR-30d-5p ABHD5 0.72 0 -0.6 0 MirTarget -0.16 1.0E-5 NA
43 hsa-miR-93-5p ABHD5 1.4 0 -0.6 0 MirTarget -0.21 0 NA
44 hsa-miR-27a-3p ABHD6 -0.37 0.00876 -1.31 0 miRNATAP -0.41 0 NA
45 hsa-miR-26b-5p ABL2 -1.11 0 0.6 0 MirTarget; miRNATAP -0.12 0.0024 NA
46 hsa-miR-30e-5p ABL2 -0.63 0 0.6 0 mirMAP -0.18 5.0E-5 NA
47 hsa-miR-378a-3p ABL2 -1.19 0 0.6 0 mirMAP -0.19 0 NA
48 hsa-miR-25-3p ABLIM1 0.63 0 0.05 0.66786 mirMAP -0.12 0.02419 NA
49 hsa-miR-186-5p ABLIM3 -0.06 0.53529 -1.27 0 mirMAP -0.21 0.0198 NA
50 hsa-miR-34a-5p ABLIM3 1.04 0 -1.27 0 miRNATAP -0.16 0.0091 NA
51 hsa-miR-455-5p ABLIM3 -0.27 0.05813 -1.27 0 miRanda -0.14 0.01683 NA
52 hsa-miR-30d-5p ABR 0.72 0 -0.28 0.11187 mirMAP -0.18 0.00599 NA
53 hsa-miR-30e-5p ABR -0.63 0 -0.28 0.11187 mirMAP -0.25 0.00305 NA
54 hsa-miR-34a-5p ABR 1.04 0 -0.28 0.11187 miRNATAP -0.19 0.00227 NA
55 hsa-miR-106b-5p ABTB2 0.65 0 -0.43 0.0031 miRNAWalker2 validate -0.25 5.0E-5 NA
56 hsa-miR-30d-5p ACAP2 0.72 0 -0.16 0.06726 MirTarget; miRNATAP -0.11 0.00125 NA
57 hsa-miR-224-5p ACAT1 2.67 0 -1.62 0 MirTarget -0.13 0 NA
58 hsa-miR-17-5p ACBD5 0.7 2.0E-5 -0.75 0 TargetScan -0.23 0 NA
59 hsa-miR-17-5p ACER2 0.7 2.0E-5 -1.22 0 TargetScan -0.41 0 NA
60 hsa-miR-455-5p ACER2 -0.27 0.05813 -1.22 0 miRanda -0.32 4.0E-5 NA
61 hsa-miR-17-5p ACER3 0.7 2.0E-5 0.02 0.84604 mirMAP -0.1 0.00064 NA
62 hsa-miR-20a-5p ACER3 0.85 0 0.02 0.84604 mirMAP -0.12 2.0E-5 NA
63 hsa-miR-148a-3p ACHE -0.75 0 0.07 0.84522 miRNATAP -0.64 0 NA
64 hsa-miR-186-5p ACHE -0.06 0.53529 0.07 0.84522 MirTarget -0.45 0.0098 NA
65 hsa-miR-194-5p ACHE -0.29 0.09961 0.07 0.84522 MirTarget -0.38 4.0E-5 NA
66 hsa-miR-22-3p ACLY -0.63 0 1.02 0 MirTarget -0.34 0 27317765; 26477310 Herein four different types of tumor cells including osteosarcoma prostate cervical and lung cancers were adopted in our study and we have demonstrated that miR-22 directly downregulated ACLY; Moreover miR-22 was proved to attenuate cancer cell proliferation and invasion as well as promote cell apoptosis via inhibiting ACLY; Additionally we confirmed the higher ACLY protein levels and the lower miR-22 expressions in hundreds of clinical samples of the four primary tumors and a negative correlation relationship between ACLY and miR-22 was clarified; These findings provide unequivocal proofs that miR-22 is responsible for the posttranscriptional regulation of ACLY which yields promising therapeutic effects in osteosarcoma prostate cervical and lung cancers;Within this cluster the cancer-associated and cardioprotective miR-22 was shown to repress fatty acid synthesis and elongation in tumour cells by targeting ATP citrate lyase and fatty acid elongase 6 as well as impairing mitochondrial one-carbon metabolism by suppression of methylene tetrahydrofolate dehydrogenase/cyclohydrolase
67 hsa-miR-146b-5p ACO1 0.42 0.04574 -0.9 0 miRanda -0.12 9.0E-5 NA
68 hsa-miR-17-5p ACOT2 0.7 2.0E-5 -1.29 0 miRNAWalker2 validate -0.19 0.00011 NA
69 hsa-miR-106b-5p ACOX1 0.65 0 -1.16 0 mirMAP -0.51 0 NA
70 hsa-miR-148b-3p ACOX1 0.27 0.00185 -1.16 0 mirMAP -0.39 0 NA
71 hsa-miR-17-5p ACOX1 0.7 2.0E-5 -1.16 0 mirMAP -0.22 0 NA
72 hsa-miR-20a-5p ACOX1 0.85 0 -1.16 0 mirMAP -0.15 0.00046 NA
73 hsa-miR-429 ACOX1 -1.4 7.0E-5 -1.16 0 miRNATAP -0.11 0 NA
74 hsa-miR-93-5p ACOX1 1.4 0 -1.16 0 mirMAP -0.41 0 NA
75 hsa-miR-429 ACOX2 -1.4 7.0E-5 -1.68 0 miRanda; miRNATAP -0.23 0 NA
76 hsa-miR-140-5p ACP1 -0.22 0.01407 0.06 0.31813 miRanda -0.11 0.00137 NA
77 hsa-miR-192-5p ACPP -0.5 0.00345 -0.47 0.14269 MirTarget -0.44 0 NA
78 hsa-miR-429 ACSL1 -1.4 7.0E-5 -2.33 0 miRNATAP -0.17 0 NA
79 hsa-miR-30e-5p ACSL3 -0.63 0 0.05 0.65044 mirMAP -0.15 0.00409 NA
80 hsa-miR-148a-3p ACSL4 -0.75 0 2.07 0 miRNATAP -0.65 0 NA
81 hsa-miR-26b-5p ACSL4 -1.11 0 2.07 0 mirMAP -0.33 0.02556 NA
82 hsa-miR-378a-3p ACSL4 -1.19 0 2.07 0 miRNAWalker2 validate -0.61 0 NA
83 hsa-miR-106b-5p ACSL6 0.65 0 0.39 0.26458 mirMAP -0.64 2.0E-5 NA
84 hsa-miR-17-5p ACSL6 0.7 2.0E-5 0.39 0.26458 mirMAP -0.37 0.00035 NA
85 hsa-miR-20a-5p ACSL6 0.85 0 0.39 0.26458 mirMAP -0.21 0.03388 NA
86 hsa-miR-429 ACSL6 -1.4 7.0E-5 0.39 0.26458 miRNATAP -0.23 0 NA
87 hsa-miR-93-5p ACSL6 1.4 0 0.39 0.26458 mirMAP -0.25 0.04057 NA
88 hsa-miR-429 ACSM2A -1.4 7.0E-5 -2.22 0 miRanda -0.3 0 NA
89 hsa-miR-34a-5p ACSS1 1.04 0 0.29 0.18285 miRNAWalker2 validate -0.23 0.00217 NA
90 hsa-miR-429 ACTN2 -1.4 7.0E-5 1.96 2.0E-5 miRanda -0.17 0.00769 NA
91 hsa-miR-378a-5p ACTN4 -1.59 0 0.36 0 miRNAWalker2 validate -0.1 0 NA
92 hsa-miR-194-5p ACTR3 -0.29 0.09961 0.05 0.43435 mirMAP -0.14 0 NA
93 hsa-miR-455-5p ACTR3 -0.27 0.05813 0.05 0.43435 miRanda -0.14 0 NA
94 hsa-miR-106b-5p ACTR3C 0.65 0 -0.99 0 mirMAP -0.5 0 NA
95 hsa-miR-17-5p ACTR3C 0.7 2.0E-5 -0.99 0 mirMAP -0.25 0 NA
96 hsa-miR-20a-5p ACTR3C 0.85 0 -0.99 0 mirMAP -0.21 1.0E-5 NA
97 hsa-miR-93-5p ACTR3C 1.4 0 -0.99 0 mirMAP -0.34 0 NA
98 hsa-miR-148a-3p ACVR1 -0.75 0 -0.44 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.13 0.0001 NA
99 hsa-miR-200b-3p ACVR1C -1.29 0.00027 -2.2 0 TargetScan -0.18 0 NA
100 hsa-miR-429 ACVR1C -1.4 7.0E-5 -2.2 0 PITA; miRanda; miRNATAP -0.17 0 NA
101 hsa-miR-92a-1-5p ACY1 0.39 0.06449 -1.04 0 MirTarget -0.15 9.0E-5 NA
102 hsa-miR-429 ACYP2 -1.4 7.0E-5 -0.82 0 miRanda -0.11 0 NA
103 hsa-miR-148a-3p ADAM10 -0.75 0 -0 0.9783 MirTarget -0.11 0.02275 NA
104 hsa-miR-455-5p ADAM10 -0.27 0.05813 -0 0.9783 miRanda -0.18 0.00053 NA
105 hsa-miR-194-3p ADAM11 -0.77 3.0E-5 1.25 0 mirMAP -0.18 0.00748 NA
106 hsa-miR-26b-5p ADAM12 -1.11 0 0.93 0.0022 mirMAP; miRNATAP -0.53 2.0E-5 NA
107 hsa-miR-455-5p ADAM15 -0.27 0.05813 1.18 0 miRanda -0.16 0.00031 NA
108 hsa-miR-148a-3p ADAM19 -0.75 0 -0.32 0.02321 mirMAP -0.33 0 NA
109 hsa-miR-30e-5p ADAM19 -0.63 0 -0.32 0.02321 MirTarget -0.17 0.01281 NA
110 hsa-miR-148a-3p ADAM22 -0.75 0 1.17 0.00038 MirTarget; miRNATAP -0.57 0 NA
111 hsa-miR-34a-5p ADAM22 1.04 0 1.17 0.00038 MirTarget; miRNATAP -0.29 0.00957 NA
112 hsa-miR-455-5p ADAM22 -0.27 0.05813 1.17 0.00038 PITA; miRanda; miRNATAP -0.45 6.0E-5 NA
113 hsa-miR-148a-3p ADAM23 -0.75 0 1.53 0.00013 MirTarget -0.47 0.00032 NA
114 hsa-miR-455-5p ADAM28 -0.27 0.05813 -0.45 0.16409 miRanda -0.53 0 NA
115 hsa-miR-148b-3p ADAM33 0.27 0.00185 0.1 0.73193 miRNAWalker2 validate -0.42 0.00932 NA
116 hsa-miR-17-5p ADAM9 0.7 2.0E-5 0.47 0.00581 TargetScan; miRNATAP -0.2 8.0E-5 NA
117 hsa-miR-20a-5p ADAM9 0.85 0 0.47 0.00581 miRNATAP -0.24 0 NA
118 hsa-miR-26b-5p ADAM9 -1.11 0 0.47 0.00581 miRNAWalker2 validate -0.24 0.00061 NA
119 hsa-miR-378a-3p ADAMDEC1 -1.19 0 1.58 4.0E-5 MirTarget -0.63 0 NA
120 hsa-miR-27b-3p ADAMTS10 -0.82 0 0.73 0.00187 MirTarget; miRNATAP -0.26 0.01059 NA
121 hsa-miR-148a-3p ADAMTS15 -0.75 0 -0.88 0.00206 MirTarget; miRNATAP -0.41 1.0E-5 NA
122 hsa-miR-148b-3p ADAMTS15 0.27 0.00185 -0.88 0.00206 MirTarget -0.55 0.00083 NA
123 hsa-miR-194-3p ADAMTS15 -0.77 3.0E-5 -0.88 0.00206 MirTarget -0.31 3.0E-5 NA
124 hsa-miR-148a-3p ADAMTS18 -0.75 0 1.44 1.0E-5 miRNATAP -0.21 0.04667 NA
125 hsa-miR-10b-5p ADAMTS2 2.87 0 -2.31 0 MirTarget -0.3 0 24897960 The addition of miR-10b RERs to the Nottingham Prognostic Index NPI provided an improvement in discrimination power and risk reclassification abilities for the clinical outcomes at 36 months
126 hsa-miR-224-5p ADAMTS2 2.67 0 -2.31 0 mirMAP -0.2 4.0E-5 NA
127 hsa-miR-34a-5p ADAMTS2 1.04 0 -2.31 0 MirTarget -0.52 0 NA
128 hsa-miR-148a-3p ADAMTS5 -0.75 0 -0.16 0.36499 miRNATAP -0.31 0 NA
129 hsa-miR-17-5p ADAMTS5 0.7 2.0E-5 -0.16 0.36499 TargetScan -0.11 0.03358 NA
130 hsa-miR-194-5p ADAMTS5 -0.29 0.09961 -0.16 0.36499 mirMAP -0.29 0 NA
131 hsa-miR-20a-5p ADAMTS5 0.85 0 -0.16 0.36499 miRNATAP -0.16 0.00122 NA
132 hsa-miR-26b-5p ADAMTS6 -1.11 0 0.7 0.00475 MirTarget -0.21 0.03525 NA
133 hsa-miR-27b-3p ADAMTS6 -0.82 0 0.7 0.00475 miRNATAP -0.26 0.01567 NA
134 hsa-miR-25-3p ADAMTSL1 0.63 0 -0.65 0.00587 miRNAWalker2 validate; miRNATAP -0.65 0 NA
135 hsa-miR-455-5p ADAMTSL1 -0.27 0.05813 -0.65 0.00587 miRanda -0.19 0.02122 NA
136 hsa-miR-17-5p ADAMTSL2 0.7 2.0E-5 -2.68 0 TargetScan -0.28 0.00562 NA
137 hsa-miR-103a-3p ADAMTSL3 0.77 0 -1.86 0 MirTarget -0.88 0 NA
138 hsa-miR-25-3p ADAMTSL3 0.63 0 -1.86 0 MirTarget; miRNATAP -0.54 0.0002 NA
139 hsa-miR-22-3p ADAP1 -0.63 0 -0.91 0.00084 mirMAP -0.52 5.0E-5 NA
140 hsa-miR-30d-5p ADAP2 0.72 0 -0.82 0 miRNAWalker2 validate -0.31 0 NA
141 hsa-miR-106b-5p ADARB1 0.65 0 -0.13 0.22208 MirTarget -0.22 0 NA
142 hsa-miR-17-5p ADARB1 0.7 2.0E-5 -0.13 0.22208 miRNAWalker2 validate; MirTarget -0.13 7.0E-5 NA
143 hsa-miR-192-5p ADARB1 -0.5 0.00345 -0.13 0.22208 mirMAP -0.13 3.0E-5 NA
144 hsa-miR-20a-5p ADARB1 0.85 0 -0.13 0.22208 MirTarget -0.11 0.00024 NA
145 hsa-miR-93-5p ADARB1 1.4 0 -0.13 0.22208 miRNAWalker2 validate; MirTarget -0.21 0 NA
146 hsa-miR-455-5p ADAT1 -0.27 0.05813 -0.15 0.33101 miRanda -0.25 1.0E-5 NA
147 hsa-miR-22-3p ADCK2 -0.63 0 0.53 0 MirTarget -0.15 0.00087 NA
148 hsa-miR-106b-5p ADCY1 0.65 0 -2.7 0 mirMAP -0.54 0.00112 NA
149 hsa-miR-10b-5p ADCY1 2.87 0 -2.7 0 mirMAP -0.13 0.03244 NA
150 hsa-miR-146b-5p ADCY1 0.42 0.04574 -2.7 0 mirMAP -0.41 0 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 INTRACELLULAR SIGNAL TRANSDUCTION 555 1572 4.618e-39 2.149e-35
2 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 576 1672 4.614e-37 1.073e-33
3 CARDIOVASCULAR SYSTEM DEVELOPMENT 323 788 3.426e-36 3.985e-33
4 CIRCULATORY SYSTEM DEVELOPMENT 323 788 3.426e-36 3.985e-33
5 NEUROGENESIS 494 1402 2.238e-34 2.083e-31
6 REGULATION OF CELL DIFFERENTIATION 516 1492 1.49e-33 1.155e-30
7 TISSUE DEVELOPMENT 520 1518 1.301e-32 8.65e-30
8 CELL DEVELOPMENT 494 1426 2.751e-32 1.6e-29
9 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 555 1656 5.286e-32 2.733e-29
10 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 377 1021 9.352e-31 4.351e-28
11 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 628 1977 6.386e-29 2.476e-26
12 REGULATION OF CELLULAR COMPONENT MOVEMENT 300 771 6.201e-29 2.476e-26
13 POSITIVE REGULATION OF MOLECULAR FUNCTION 571 1791 1.243e-26 4.447e-24
14 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 574 1805 1.807e-26 5.604e-24
15 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 434 1275 1.754e-26 5.604e-24
16 VASCULATURE DEVELOPMENT 201 469 1.144e-25 3.327e-23
17 POSITIVE REGULATION OF GENE EXPRESSION 552 1733 1.297e-25 3.353e-23
18 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 395 1142 1.285e-25 3.353e-23
19 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 343 957 2.534e-25 6.207e-23
20 HEART DEVELOPMENT 196 466 7.308e-24 1.7e-21
21 POSITIVE REGULATION OF CATALYTIC ACTIVITY 489 1518 8.315e-24 1.842e-21
22 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 557 1784 1.442e-23 3.05e-21
23 RESPONSE TO OXYGEN CONTAINING COMPOUND 450 1381 5.188e-23 1.05e-20
24 RESPONSE TO ENDOGENOUS STIMULUS 468 1450 5.678e-23 1.057e-20
25 REGULATION OF CELL DEVELOPMENT 302 836 5.614e-23 1.057e-20
26 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 568 1848 2.755e-22 4.93e-20
27 BLOOD VESSEL MORPHOGENESIS 160 364 5.053e-22 8.708e-20
28 NEURON DIFFERENTIATION 309 874 8.311e-22 1.381e-19
29 NEGATIVE REGULATION OF CELL COMMUNICATION 395 1192 1.098e-21 1.761e-19
30 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 205 513 1.168e-21 1.811e-19
31 REGULATION OF TRANSPORT 554 1804 1.235e-21 1.854e-19
32 POSITIVE REGULATION OF CELL DIFFERENTIATION 294 823 1.503e-21 2.134e-19
33 REGULATION OF PHOSPHORUS METABOLIC PROCESS 506 1618 1.513e-21 2.134e-19
34 TUBE DEVELOPMENT 216 552 1.992e-21 2.727e-19
35 PROTEIN PHOSPHORYLATION 326 944 4.235e-21 5.63e-19
36 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 446 1395 5.26e-21 6.799e-19
37 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 471 1492 6.024e-21 7.575e-19
38 ORGAN MORPHOGENESIS 297 841 6.596e-21 8.076e-19
39 REGULATION OF PROTEIN MODIFICATION PROCESS 526 1710 1.073e-20 1.28e-18
40 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 435 1360 1.563e-20 1.818e-18
41 REGULATION OF NEURON DIFFERENTIATION 214 554 1.912e-20 2.169e-18
42 POSITIVE REGULATION OF CELL COMMUNICATION 479 1532 2.246e-20 2.488e-18
43 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 267 740 2.499e-20 2.704e-18
44 REGULATION OF GTPASE ACTIVITY 248 673 2.582e-20 2.73e-18
45 LOCOMOTION 368 1114 5.565e-20 5.754e-18
46 PHOSPHORYLATION 398 1228 6.356e-20 6.429e-18
47 EMBRYO DEVELOPMENT 308 894 8.414e-20 8.33e-18
48 TISSUE MORPHOGENESIS 206 533 9.365e-20 8.893e-18
49 PROTEIN LOCALIZATION 546 1805 9.282e-20 8.893e-18
50 REGULATION OF CELL DEATH 459 1472 2.758e-19 2.566e-17
51 EPITHELIUM DEVELOPMENT 320 945 2.993e-19 2.731e-17
52 NEGATIVE REGULATION OF GENE EXPRESSION 464 1493 3.441e-19 3.079e-17
53 CELLULAR COMPONENT MORPHOGENESIS 307 900 5.069e-19 4.45e-17
54 REGULATION OF CELL PROLIFERATION 464 1496 5.232e-19 4.508e-17
55 HEAD DEVELOPMENT 254 709 6.32e-19 5.347e-17
56 CENTRAL NERVOUS SYSTEM DEVELOPMENT 298 872 1.284e-18 1.067e-16
57 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 264 750 1.795e-18 1.466e-16
58 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 333 1008 3.783e-18 3.035e-16
59 REGULATION OF HYDROLASE ACTIVITY 416 1327 5.935e-18 4.68e-16
60 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 331 1004 6.773e-18 5.252e-16
61 POSITIVE REGULATION OF RESPONSE TO STIMULUS 568 1929 8.174e-18 6.235e-16
62 RESPONSE TO EXTERNAL STIMULUS 540 1821 1.335e-17 1.002e-15
63 SKELETAL SYSTEM DEVELOPMENT 177 455 1.792e-17 1.324e-15
64 POSITIVE REGULATION OF HYDROLASE ACTIVITY 302 905 3.269e-17 2.377e-15
65 REGULATION OF CELL PROJECTION ORGANIZATION 206 558 3.667e-17 2.625e-15
66 REGULATION OF NEURON PROJECTION DEVELOPMENT 162 408 4.578e-17 3.228e-15
67 CELL MOTILITY 282 835 6.738e-17 4.61e-15
68 LOCALIZATION OF CELL 282 835 6.738e-17 4.61e-15
69 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 460 1517 7.09e-17 4.781e-15
70 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 320 983 1.871e-16 1.243e-14
71 RESPONSE TO ORGANIC CYCLIC COMPOUND 302 917 2.464e-16 1.615e-14
72 RESPONSE TO ABIOTIC STIMULUS 330 1024 3.069e-16 1.983e-14
73 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 120 278 3.995e-16 2.546e-14
74 POSITIVE REGULATION OF LOCOMOTION 163 420 4.395e-16 2.764e-14
75 MORPHOGENESIS OF AN EPITHELIUM 157 400 4.751e-16 2.948e-14
76 RESPONSE TO LIPID 293 888 5.367e-16 3.286e-14
77 REGULATION OF CELL ADHESION 222 629 7.463e-16 4.51e-14
78 ANGIOGENESIS 124 293 8.101e-16 4.832e-14
79 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 142 352 8.529e-16 5.023e-14
80 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 357 1135 9.773e-16 5.684e-14
81 NEURON PROJECTION DEVELOPMENT 198 545 1.031e-15 5.921e-14
82 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 268 799 1.077e-15 6.114e-14
83 REGULATION OF TRANSFERASE ACTIVITY 307 946 1.275e-15 7.146e-14
84 NEURON DEVELOPMENT 237 687 1.529e-15 8.468e-14
85 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 330 1036 1.902e-15 1.029e-13
86 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 330 1036 1.902e-15 1.029e-13
87 REGULATION OF CELL MORPHOGENESIS 199 552 2.157e-15 1.153e-13
88 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 237 689 2.222e-15 1.175e-13
89 EMBRYONIC MORPHOGENESIS 195 539 2.771e-15 1.448e-13
90 CELL PROJECTION ORGANIZATION 294 902 2.843e-15 1.47e-13
91 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 267 801 2.879e-15 1.472e-13
92 REGULATION OF CELLULAR LOCALIZATION 391 1277 3.907e-15 1.976e-13
93 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 358 1152 6.223e-15 3.113e-13
94 RESPONSE TO HORMONE 289 893 1.352e-14 6.695e-13
95 TUBE MORPHOGENESIS 130 323 1.736e-14 8.505e-13
96 NEGATIVE REGULATION OF CELL DEATH 283 872 1.758e-14 8.519e-13
97 REGULATION OF CELL CYCLE 303 949 2.09e-14 1.002e-12
98 CELL PROLIFERATION 229 672 2.116e-14 1.005e-12
99 REGULATION OF KINASE ACTIVITY 257 776 2.271e-14 1.067e-12
100 POSITIVE REGULATION OF CELL PROLIFERATION 267 814 2.504e-14 1.156e-12
101 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 143 368 2.509e-14 1.156e-12
102 CELL DEATH 316 1001 2.926e-14 1.335e-12
103 CELLULAR MACROMOLECULE LOCALIZATION 376 1234 3.04e-14 1.373e-12
104 DEVELOPMENTAL GROWTH 132 333 4.313e-14 1.93e-12
105 RESPONSE TO NITROGEN COMPOUND 278 859 4.423e-14 1.96e-12
106 POSITIVE REGULATION OF TRANSPORT 298 936 5.168e-14 2.269e-12
107 NEURON PROJECTION MORPHOGENESIS 152 402 5.569e-14 2.422e-12
108 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 195 554 6.039e-14 2.602e-12
109 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 281 876 1.052e-13 4.491e-12
110 CONNECTIVE TISSUE DEVELOPMENT 88 194 1.084e-13 4.584e-12
111 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 161 437 1.319e-13 5.528e-12
112 GROWTH 153 410 1.615e-13 6.71e-12
113 ESTABLISHMENT OF PROTEIN LOCALIZATION 420 1423 1.912e-13 7.874e-12
114 MUSCLE STRUCTURE DEVELOPMENT 159 432 2.06e-13 8.409e-12
115 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 131 337 2.967e-13 1.2e-11
116 TAXIS 167 464 4.68e-13 1.877e-11
117 ACTIN FILAMENT BASED PROCESS 163 450 4.848e-13 1.928e-11
118 POSITIVE REGULATION OF CELL DEATH 205 605 9.392e-13 3.703e-11
119 POSITIVE REGULATION OF CELL DEVELOPMENT 168 472 1.172e-12 4.583e-11
120 REGULATION OF DEVELOPMENTAL GROWTH 115 289 1.374e-12 5.286e-11
121 REGULATION OF GROWTH 212 633 1.375e-12 5.286e-11
122 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 207 616 1.777e-12 6.779e-11
123 MUSCLE TISSUE DEVELOPMENT 110 275 2.843e-12 1.076e-10
124 UROGENITAL SYSTEM DEVELOPMENT 117 299 3.282e-12 1.231e-10
125 REGULATION OF PROTEIN LOCALIZATION 294 950 3.329e-12 1.239e-10
126 POSITIVE REGULATION OF KINASE ACTIVITY 169 482 4.214e-12 1.556e-10
127 MESENCHYMAL CELL DIFFERENTIATION 65 134 4.372e-12 1.602e-10
128 REGULATION OF RESPONSE TO STRESS 424 1468 4.811e-12 1.735e-10
129 NEURON PROJECTION GUIDANCE 88 205 4.791e-12 1.735e-10
130 EXTRACELLULAR STRUCTURE ORGANIZATION 118 304 4.974e-12 1.78e-10
131 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 164 465 5.11e-12 1.815e-10
132 BIOLOGICAL ADHESION 314 1032 5.722e-12 2.017e-10
133 GLAND DEVELOPMENT 144 395 6.431e-12 2.25e-10
134 RESPONSE TO DRUG 154 431 7.286e-12 2.53e-10
135 RESPONSE TO MECHANICAL STIMULUS 89 210 8.501e-12 2.93e-10
136 SENSORY ORGAN DEVELOPMENT 171 493 8.715e-12 2.982e-10
137 REGULATION OF CATABOLIC PROCESS 235 731 9.321e-12 3.166e-10
138 CELLULAR RESPONSE TO HORMONE STIMULUS 187 552 9.731e-12 3.281e-10
139 IMMUNE SYSTEM DEVELOPMENT 195 582 1.063e-11 3.559e-10
140 REGULATION OF CELLULAR RESPONSE TO STRESS 224 691 1.188e-11 3.948e-10
141 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 164 470 1.359e-11 4.454e-10
142 NEGATIVE REGULATION OF CELL PROLIFERATION 211 643 1.357e-11 4.454e-10
143 OSSIFICATION 101 251 1.449e-11 4.714e-10
144 RESPONSE TO GROWTH FACTOR 165 475 1.772e-11 5.726e-10
145 STEM CELL DIFFERENTIATION 82 190 1.813e-11 5.819e-10
146 POSITIVE REGULATION OF NEURON DIFFERENTIATION 117 306 1.918e-11 6.112e-10
147 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 73 162 1.953e-11 6.18e-10
148 NEGATIVE REGULATION OF CELL DIFFERENTIATION 201 609 2.35e-11 7.388e-10
149 REGULATION OF VASCULATURE DEVELOPMENT 95 233 2.42e-11 7.559e-10
150 REGULATION OF INTRACELLULAR TRANSPORT 204 621 2.676e-11 8.3e-10
151 CELL PART MORPHOGENESIS 207 633 3.027e-11 9.266e-10
152 CELL CYCLE 382 1316 3.026e-11 9.266e-10
153 FOREBRAIN DEVELOPMENT 131 357 3.434e-11 1.044e-09
154 HEART MORPHOGENESIS 88 212 4.226e-11 1.277e-09
155 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 144 404 4.276e-11 1.283e-09
156 CELLULAR RESPONSE TO STRESS 442 1565 5.566e-11 1.66e-09
157 ESTABLISHMENT OF LOCALIZATION IN CELL 469 1676 5.831e-11 1.728e-09
158 SINGLE ORGANISM CELLULAR LOCALIZATION 275 898 6.01e-11 1.77e-09
159 REGULATION OF OSSIFICATION 77 178 6.46e-11 1.891e-09
160 POSITIVE REGULATION OF CELL CYCLE 123 332 6.648e-11 1.933e-09
161 REGULATION OF ANATOMICAL STRUCTURE SIZE 162 472 7.774e-11 2.247e-09
162 CYTOSKELETON ORGANIZATION 259 838 7.974e-11 2.29e-09
163 TELENCEPHALON DEVELOPMENT 92 228 9.692e-11 2.767e-09
164 REGULATION OF CELLULAR PROTEIN LOCALIZATION 183 552 1.238e-10 3.513e-09
165 MESENCHYME DEVELOPMENT 80 190 1.391e-10 3.922e-09
166 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 78 184 1.594e-10 4.467e-09
167 CELLULAR RESPONSE TO EXTERNAL STIMULUS 102 264 1.853e-10 5.164e-09
168 REGULATION OF MAPK CASCADE 211 660 1.906e-10 5.279e-09
169 WNT SIGNALING PATHWAY 127 351 1.973e-10 5.433e-09
170 PALLIUM DEVELOPMENT 68 153 1.988e-10 5.44e-09
171 REGULATION OF EPITHELIAL CELL PROLIFERATION 108 285 2.091e-10 5.689e-09
172 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 113 303 2.481e-10 6.712e-09
173 CELLULAR RESPONSE TO LIPID 156 457 2.741e-10 7.372e-09
174 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 61 133 3.577e-10 9.511e-09
175 NEGATIVE REGULATION OF PHOSPHORYLATION 146 422 3.558e-10 9.511e-09
176 REGULATION OF SYSTEM PROCESS 169 507 3.99e-10 1.055e-08
177 IMMUNE SYSTEM PROCESS 538 1984 4.153e-10 1.092e-08
178 REGULATION OF CELL GROWTH 137 391 4.76e-10 1.244e-08
179 POSITIVE REGULATION OF CATABOLIC PROCESS 138 395 5.141e-10 1.336e-08
180 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 166 498 5.708e-10 1.476e-08
181 CARTILAGE DEVELOPMENT 65 147 6.427e-10 1.652e-08
182 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 91 232 7.042e-10 1.8e-08
183 RESPONSE TO WOUNDING 183 563 7.331e-10 1.864e-08
184 REGULATION OF CYTOPLASMIC TRANSPORT 161 481 7.374e-10 1.865e-08
185 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 90 229 7.748e-10 1.949e-08
186 CARDIAC SEPTUM DEVELOPMENT 44 85 8.956e-10 2.24e-08
187 NEGATIVE REGULATION OF CELL ADHESION 88 223 9.363e-10 2.33e-08
188 REGULATION OF OSTEOBLAST DIFFERENTIATION 53 112 1.253e-09 3.102e-08
189 REGULATION OF NEURON APOPTOTIC PROCESS 78 192 1.742e-09 4.289e-08
190 CELL CYCLE PROCESS 314 1081 1.821e-09 4.458e-08
191 REGULATION OF CELLULAR COMPONENT SIZE 120 337 1.884e-09 4.589e-08
192 MEMBRANE ORGANIZATION 268 899 2.058e-09 4.962e-08
193 EMBRYONIC ORGAN DEVELOPMENT 139 406 2.055e-09 4.962e-08
194 NEGATIVE REGULATION OF MOLECULAR FUNCTION 313 1079 2.26e-09 5.42e-08
195 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 175 541 2.593e-09 6.155e-08
196 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 175 541 2.593e-09 6.155e-08
197 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 48 99 2.72e-09 6.392e-08
198 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 48 99 2.72e-09 6.392e-08
199 IN UTERO EMBRYONIC DEVELOPMENT 112 311 3.111e-09 7.274e-08
200 CELLULAR RESPONSE TO NITROGEN COMPOUND 165 505 3.321e-09 7.726e-08
201 GLAND MORPHOGENESIS 47 97 4.074e-09 9.431e-08
202 RESPONSE TO STEROID HORMONE 162 497 5.56e-09 1.281e-07
203 CARDIAC CHAMBER DEVELOPMENT 62 144 5.64e-09 1.293e-07
204 FORMATION OF PRIMARY GERM LAYER 51 110 6.141e-09 1.401e-07
205 RESPONSE TO OXYGEN LEVELS 111 311 6.497e-09 1.475e-07
206 VESICLE MEDIATED TRANSPORT 350 1239 6.542e-09 1.478e-07
207 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 312 1087 7.985e-09 1.795e-07
208 CELLULAR RESPONSE TO ABIOTIC STIMULUS 97 263 8.718e-09 1.95e-07
209 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 145 437 9.74e-09 2.158e-07
210 REGULATION OF ORGANELLE ORGANIZATION 334 1178 9.713e-09 2.158e-07
211 BEHAVIOR 166 516 1.024e-08 2.257e-07
212 NEGATIVE REGULATION OF GROWTH 89 236 1.037e-08 2.277e-07
213 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 220 724 1.072e-08 2.341e-07
214 REGULATION OF CELL CELL ADHESION 129 380 1.381e-08 2.996e-07
215 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 48 103 1.384e-08 2.996e-07
216 INTRACELLULAR PROTEIN TRANSPORT 234 781 1.392e-08 2.998e-07
217 RESPONSE TO ALCOHOL 124 362 1.451e-08 3.111e-07
218 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 62 147 1.465e-08 3.128e-07
219 REGULATION OF HOMEOSTATIC PROCESS 147 447 1.483e-08 3.151e-07
220 KIDNEY EPITHELIUM DEVELOPMENT 55 125 1.602e-08 3.389e-07
221 WOUND HEALING 153 470 1.618e-08 3.407e-07
222 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 77 197 1.674e-08 3.509e-07
223 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 270 926 1.791e-08 3.737e-07
224 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 191 616 1.946e-08 4.043e-07
225 CELL JUNCTION ASSEMBLY 56 129 2.132e-08 4.41e-07
226 REGULATION OF AXONOGENESIS 68 168 2.228e-08 4.587e-07
227 ARTERY DEVELOPMENT 38 75 2.654e-08 5.439e-07
228 REGULATION OF CELL SIZE 69 172 2.699e-08 5.508e-07
229 MYELOID CELL DIFFERENTIATION 74 189 2.9e-08 5.892e-07
230 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 83 220 3.14e-08 6.352e-07
231 REGULATION OF EPITHELIAL CELL MIGRATION 67 166 3.217e-08 6.479e-07
232 RESPONSE TO EXTRACELLULAR STIMULUS 144 441 3.429e-08 6.877e-07
233 EPITHELIAL TO MESENCHYMAL TRANSITION 31 56 3.492e-08 6.974e-07
234 ORGANELLE LOCALIZATION 137 415 3.508e-08 6.976e-07
235 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 79 207 3.747e-08 7.419e-07
236 REPRODUCTIVE SYSTEM DEVELOPMENT 135 408 3.772e-08 7.437e-07
237 ORGANOPHOSPHATE METABOLIC PROCESS 258 885 3.814e-08 7.488e-07
238 REGULATION OF ORGAN MORPHOGENESIS 89 242 4.106e-08 8.027e-07
239 MORPHOGENESIS OF A BRANCHING STRUCTURE 67 167 4.248e-08 8.271e-07
240 AMEBOIDAL TYPE CELL MIGRATION 63 154 4.508e-08 8.74e-07
241 NEGATIVE REGULATION OF CELL DEVELOPMENT 106 303 4.682e-08 9.039e-07
242 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 74 191 4.847e-08 9.281e-07
243 REGULATION OF VESICLE MEDIATED TRANSPORT 149 462 4.836e-08 9.281e-07
244 SINGLE ORGANISM BEHAVIOR 128 384 5.243e-08 9.998e-07
245 CATABOLIC PROCESS 473 1773 5.318e-08 1.01e-06
246 SECRETION BY CELL 155 486 5.875e-08 1.111e-06
247 PROTEIN AUTOPHOSPHORYLATION 74 192 6.235e-08 1.175e-06
248 CARDIAC SEPTUM MORPHOGENESIS 28 49 6.362e-08 1.189e-06
249 REGULATION OF BINDING 100 283 6.339e-08 1.189e-06
250 MUSCLE CELL DIFFERENTIATION 87 237 6.392e-08 1.19e-06
251 REGULATION OF ACTIN FILAMENT BASED PROCESS 108 312 6.577e-08 1.219e-06
252 CELLULAR RESPONSE TO MECHANICAL STIMULUS 39 80 6.78e-08 1.252e-06
253 RHYTHMIC PROCESS 104 298 7.173e-08 1.319e-06
254 ENDOMEMBRANE SYSTEM ORGANIZATION 149 465 7.617e-08 1.395e-06
255 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 60 146 7.69e-08 1.403e-06
256 REGULATION OF NEURON DEATH 91 252 7.813e-08 1.42e-06
257 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 73 190 8.852e-08 1.603e-06
258 RESPIRATORY SYSTEM DEVELOPMENT 75 197 9.217e-08 1.662e-06
259 NEGATIVE REGULATION OF CELL GROWTH 67 170 9.559e-08 1.717e-06
260 NEGATIVE REGULATION OF CELL CYCLE 140 433 1.03e-07 1.843e-06
261 CELLULAR RESPONSE TO ALCOHOL 50 115 1.122e-07 2.001e-06
262 RESPONSE TO PEPTIDE 132 404 1.212e-07 2.153e-06
263 REGULATION OF MAP KINASE ACTIVITY 109 319 1.226e-07 2.169e-06
264 EPITHELIAL CELL DIFFERENTIATION 156 495 1.247e-07 2.198e-06
265 PROTEIN LOCALIZATION TO CELL PERIPHERY 61 151 1.255e-07 2.204e-06
266 SECRETION 180 588 1.336e-07 2.338e-06
267 CELL JUNCTION ORGANIZATION 71 185 1.39e-07 2.422e-06
268 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 93 262 1.422e-07 2.469e-06
269 NEGATIVE REGULATION OF LOCOMOTION 93 263 1.738e-07 3.007e-06
270 REGULATION OF WNT SIGNALING PATHWAY 106 310 1.746e-07 3.009e-06
271 REGULATION OF JNK CASCADE 63 159 1.816e-07 3.117e-06
272 CARDIAC CHAMBER MORPHOGENESIS 46 104 1.928e-07 3.297e-06
273 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 100 289 2.029e-07 3.421e-06
274 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 125 381 2.016e-07 3.421e-06
275 REGULATION OF EXTENT OF CELL GROWTH 45 101 2.013e-07 3.421e-06
276 REGULATION OF DENDRITE DEVELOPMENT 51 120 2.024e-07 3.421e-06
277 CELLULAR RESPONSE TO OXYGEN LEVELS 58 143 2.154e-07 3.619e-06
278 COLLAGEN FIBRIL ORGANIZATION 23 38 2.268e-07 3.797e-06
279 ION TRANSPORT 346 1262 2.337e-07 3.896e-06
280 CARDIAC MUSCLE TISSUE DEVELOPMENT 57 140 2.344e-07 3.896e-06
281 MITOTIC CELL CYCLE 224 766 2.354e-07 3.897e-06
282 REGULATION OF SECRETION 207 699 2.492e-07 4.111e-06
283 POSITIVE REGULATION OF CELL CYCLE PROCESS 88 247 2.526e-07 4.154e-06
284 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 58 144 2.855e-07 4.677e-06
285 CARBOHYDRATE DERIVATIVE METABOLIC PROCESS 293 1047 2.994e-07 4.881e-06
286 PROTEIN LOCALIZATION TO MEMBRANE 123 376 3e-07 4.881e-06
287 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 74 199 3.331e-07 5.401e-06
288 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 39 84 3.466e-07 5.599e-06
289 NEURAL CREST CELL DIFFERENTIATION 36 75 3.496e-07 5.628e-06
290 POSITIVE REGULATION OF GROWTH 85 238 3.564e-07 5.698e-06
291 REGULATION OF MITOTIC CELL CYCLE 147 468 3.561e-07 5.698e-06
292 REGULATION OF ION TRANSPORT 179 592 3.629e-07 5.783e-06
293 GASTRULATION 61 155 3.731e-07 5.925e-06
294 PLASMA MEMBRANE ORGANIZATION 75 203 3.747e-07 5.931e-06
295 REGULATION OF MUSCLE CELL DIFFERENTIATION 60 152 4.102e-07 6.469e-06
296 REGULATION OF CELL CYCLE PROCESS 170 558 4.174e-07 6.562e-06
297 MITOTIC DNA INTEGRITY CHECKPOINT 44 100 4.222e-07 6.614e-06
298 REGULATION OF PROTEIN IMPORT 69 183 4.513e-07 7.047e-06
299 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 79 218 4.635e-07 7.213e-06
300 POSITIVE REGULATION OF MAPK CASCADE 147 470 4.71e-07 7.305e-06
301 HOMEOSTATIC PROCESS 362 1337 4.771e-07 7.375e-06
302 BONE DEVELOPMENT 61 156 4.848e-07 7.444e-06
303 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 61 156 4.848e-07 7.444e-06
304 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 34 70 5.169e-07 7.912e-06
305 REGULATION OF CYTOSKELETON ORGANIZATION 155 502 5.544e-07 8.457e-06
306 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 45 104 5.605e-07 8.523e-06
307 REGULATION OF CELLULAR COMPONENT BIOGENESIS 222 767 6.198e-07 9.393e-06
308 REGULATION OF EMBRYONIC DEVELOPMENT 48 114 6.362e-07 9.611e-06
309 MUSCLE ORGAN DEVELOPMENT 95 277 6.384e-07 9.613e-06
310 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 201 684 6.747e-07 1.013e-05
311 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 60 154 6.923e-07 1.036e-05
312 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 54 134 7.09e-07 1.055e-05
313 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 57 144 7.099e-07 1.055e-05
314 CELLULAR RESPONSE TO PEPTIDE 94 274 7.182e-07 1.064e-05
315 REGULATION OF PROTEIN CATABOLIC PROCESS 126 393 7.277e-07 1.075e-05
316 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 180 602 7.591e-07 1.118e-05
317 CEREBRAL CORTEX DEVELOPMENT 45 105 7.771e-07 1.134e-05
318 ORGAN GROWTH 33 68 7.765e-07 1.134e-05
319 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 53 131 7.736e-07 1.134e-05
320 EYE DEVELOPMENT 108 326 7.854e-07 1.142e-05
321 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 44 102 8.259e-07 1.197e-05
322 DIGESTIVE SYSTEM DEVELOPMENT 58 148 8.41e-07 1.215e-05
323 RESPONSE TO RADIATION 131 413 8.474e-07 1.221e-05
324 SINGLE ORGANISM CELL ADHESION 143 459 8.594e-07 1.234e-05
325 VENTRICULAR SEPTUM DEVELOPMENT 28 54 9.67e-07 1.384e-05
326 REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 46 109 9.992e-07 1.426e-05
327 ESTABLISHMENT OF PROTEIN LOCALIZATION TO PLASMA MEMBRANE 40 90 1.016e-06 1.446e-05
328 FAT CELL DIFFERENTIATION 45 106 1.07e-06 1.518e-05
329 STEM CELL PROLIFERATION 30 60 1.097e-06 1.546e-05
330 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 30 60 1.097e-06 1.546e-05
331 STRIATED MUSCLE CELL DIFFERENTIATION 65 173 1.107e-06 1.557e-05
332 TUBE FORMATION 52 129 1.118e-06 1.567e-05
333 REGULATION OF CHEMOTAXIS 67 180 1.126e-06 1.574e-05
334 REGULATION OF MUSCLE TISSUE DEVELOPMENT 44 103 1.143e-06 1.592e-05
335 NEGATIVE REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 32 66 1.167e-06 1.606e-05
336 MESODERM MORPHOGENESIS 32 66 1.167e-06 1.606e-05
337 NEGATIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 32 66 1.167e-06 1.606e-05
338 REGULATION OF BLOOD CIRCULATION 99 295 1.159e-06 1.606e-05
339 REGULATION OF CELL CYCLE PHASE TRANSITION 106 321 1.175e-06 1.612e-05
340 POSITIVE REGULATION OF AXONOGENESIS 33 69 1.181e-06 1.617e-05
341 OSTEOBLAST DIFFERENTIATION 51 126 1.22e-06 1.66e-05
342 LIMBIC SYSTEM DEVELOPMENT 43 100 1.216e-06 1.66e-05
343 REGULATION OF METAL ION TRANSPORT 107 325 1.229e-06 1.667e-05
344 RAS PROTEIN SIGNAL TRANSDUCTION 56 143 1.325e-06 1.792e-05
345 MULTICELLULAR ORGANISMAL SIGNALING 50 123 1.329e-06 1.792e-05
346 NEURON MIGRATION 46 110 1.361e-06 1.83e-05
347 POSITIVE REGULATION OF PROTEIN CATABOLIC PROCESS 90 263 1.382e-06 1.854e-05
348 EAR DEVELOPMENT 71 195 1.414e-06 1.885e-05
349 REGULATION OF MUSCLE SYSTEM PROCESS 71 195 1.414e-06 1.885e-05
350 LUNG ALVEOLUS DEVELOPMENT 23 41 1.493e-06 1.984e-05
351 REGULATION OF BODY FLUID LEVELS 154 506 1.542e-06 2.044e-05
352 PEPTIDYL AMINO ACID MODIFICATION 238 841 1.617e-06 2.138e-05
353 DEPHOSPHORYLATION 96 286 1.654e-06 2.18e-05
354 CHEMICAL HOMEOSTASIS 246 874 1.698e-06 2.23e-05
355 REGULATION OF ENDOTHELIAL CELL MIGRATION 47 114 1.702e-06 2.23e-05
356 RESPONSE TO CARBOHYDRATE 63 168 1.735e-06 2.267e-05
357 HIPPOCAMPUS DEVELOPMENT 34 73 1.757e-06 2.276e-05
358 EMBRYONIC ORGAN MORPHOGENESIS 94 279 1.761e-06 2.276e-05
359 REGULATION OF ORGAN GROWTH 34 73 1.757e-06 2.276e-05
360 G1 DNA DAMAGE CHECKPOINT 34 73 1.757e-06 2.276e-05
361 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 32 67 1.773e-06 2.286e-05
362 NEGATIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 42 98 1.79e-06 2.301e-05
363 RESPONSE TO PURINE CONTAINING COMPOUND 60 158 1.879e-06 2.409e-05
364 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 49 121 1.924e-06 2.453e-05
365 SINGLE ORGANISM CATABOLIC PROCESS 266 957 1.924e-06 2.453e-05
366 DEVELOPMENTAL MATURATION 70 193 1.963e-06 2.496e-05
367 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 77 218 2.016e-06 2.556e-05
368 NEGATIVE REGULATION OF TRANSPORT 141 458 2.119e-06 2.679e-05
369 POST EMBRYONIC DEVELOPMENT 39 89 2.127e-06 2.682e-05
370 POSITIVE REGULATION OF INTRACELLULAR TRANSPORT 118 370 2.162e-06 2.719e-05
371 PROTEIN DEPHOSPHORYLATION 69 190 2.197e-06 2.756e-05
372 REGULATION OF AXON GUIDANCE 22 39 2.223e-06 2.773e-05
373 REGULATION OF IMMUNE SYSTEM PROCESS 373 1403 2.217e-06 2.773e-05
374 PIGMENTATION 38 86 2.235e-06 2.78e-05
375 NEPHRON DEVELOPMENT 47 115 2.28e-06 2.829e-05
376 NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS 53 135 2.3e-06 2.847e-05
377 SKELETAL SYSTEM MORPHOGENESIS 72 201 2.386e-06 2.944e-05
378 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 62 166 2.439e-06 3.002e-05
379 REGULATION OF HOMOTYPIC CELL CELL ADHESION 101 307 2.502e-06 3.072e-05
380 CARDIAC MUSCLE CELL DIFFERENTIATION 34 74 2.58e-06 3.16e-05
381 CARDIAC EPITHELIAL TO MESENCHYMAL TRANSITION 16 24 2.621e-06 3.2e-05
382 CARDIOCYTE DIFFERENTIATION 41 96 2.634e-06 3.208e-05
383 RESPONSE TO FLUID SHEAR STRESS 20 34 2.646e-06 3.214e-05
384 MITOTIC CELL CYCLE CHECKPOINT 54 139 2.704e-06 3.277e-05
385 CELL FATE COMMITMENT 79 227 2.873e-06 3.473e-05
386 REGULATION OF FAT CELL DIFFERENTIATION 44 106 2.901e-06 3.488e-05
387 CARDIAC VENTRICLE DEVELOPMENT 44 106 2.901e-06 3.488e-05
388 REGULATION OF LIPID METABOLIC PROCESS 94 282 2.952e-06 3.54e-05
389 ENDOTHELIUM DEVELOPMENT 39 90 2.977e-06 3.561e-05
390 CARDIAC MUSCLE CELL ACTION POTENTIAL 21 37 3.309e-06 3.942e-05
391 POSITIVE REGULATION OF OSSIFICATION 37 84 3.313e-06 3.942e-05
392 ACTIVATION OF PROTEIN KINASE ACTIVITY 93 279 3.324e-06 3.945e-05
393 CELL SUBSTRATE ADHESION 61 164 3.423e-06 4.053e-05
394 REGULATION OF HEART CONTRACTION 77 221 3.631e-06 4.289e-05
395 NEGATIVE REGULATION OF CELL CYCLE PROCESS 75 214 3.778e-06 4.45e-05
396 ENERGY RESERVE METABOLIC PROCESS 33 72 3.855e-06 4.53e-05
397 EXOCYTOSIS 101 310 4.052e-06 4.749e-05
398 RESPONSE TO CYTOKINE 204 714 4.539e-06 5.306e-05
399 ANION TRANSPORT 152 507 4.58e-06 5.341e-05
400 PALATE DEVELOPMENT 37 85 4.654e-06 5.387e-05
401 POSITIVE REGULATION OF CELL GROWTH 56 148 4.633e-06 5.387e-05
402 POSITIVE REGULATION OF CELL CYCLE ARREST 37 85 4.654e-06 5.387e-05
403 APPENDAGE DEVELOPMENT 62 169 4.814e-06 5.53e-05
404 ORGANIC ANION TRANSPORT 121 387 4.797e-06 5.53e-05
405 LIMB DEVELOPMENT 62 169 4.814e-06 5.53e-05
406 REGULATION OF CELL ACTIVATION 146 484 4.875e-06 5.587e-05
407 CARDIAC CONDUCTION 36 82 4.909e-06 5.612e-05
408 GLYCOPROTEIN METABOLIC PROCESS 112 353 5.059e-06 5.77e-05
409 SYNAPSE ORGANIZATION 55 145 5.148e-06 5.842e-05
410 NEGATIVE REGULATION OF MAPK CASCADE 55 145 5.148e-06 5.842e-05
411 REGULATION OF PEPTIDE TRANSPORT 86 256 5.41e-06 6.125e-05
412 POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT 93 282 5.485e-06 6.185e-05
413 CELL GROWTH 52 135 5.49e-06 6.185e-05
414 CELL ACTIVATION 167 568 5.639e-06 6.337e-05
415 NEURAL PRECURSOR CELL PROLIFERATION 32 70 5.76e-06 6.454e-05
416 CELL CELL ADHESION 177 608 5.771e-06 6.454e-05
417 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 46 115 5.805e-06 6.477e-05
418 AGING 88 264 6.015e-06 6.68e-05
419 ESTABLISHMENT OF PROTEIN LOCALIZATION TO MEMBRANE 88 264 6.015e-06 6.68e-05
420 SMOOTH MUSCLE TISSUE DEVELOPMENT 13 18 6.116e-06 6.759e-05
421 CENTROSOME LOCALIZATION 13 18 6.116e-06 6.759e-05
422 VESICLE LOCALIZATION 77 224 6.404e-06 7.044e-05
423 CELLULAR RESPONSE TO EXTRACELLULAR STIMULUS 67 188 6.401e-06 7.044e-05
424 DNA INTEGRITY CHECKPOINT 55 146 6.54e-06 7.177e-05
425 SECOND MESSENGER MEDIATED SIGNALING 59 160 6.716e-06 7.353e-05
426 CELL DIVISION 139 460 7.386e-06 8.067e-05
427 NEGATIVE REGULATION OF NEURON DEATH 62 171 7.448e-06 8.116e-05
428 REGULATION OF HEMOPOIESIS 101 314 7.539e-06 8.196e-05
429 TRANSITION METAL ION HOMEOSTASIS 43 106 7.575e-06 8.216e-05
430 MULTICELLULAR ORGANISM METABOLIC PROCESS 39 93 7.771e-06 8.409e-05
431 REGULATION OF DENDRITE MORPHOGENESIS 33 74 8.005e-06 8.642e-05
432 COGNITION 84 251 8.153e-06 8.781e-05
433 REGULATION OF PROTEIN TARGETING 99 307 8.192e-06 8.803e-05
434 LEUKOCYTE DIFFERENTIATION 95 292 8.24e-06 8.826e-05
435 REGULATION OF MUSCLE ORGAN DEVELOPMENT 42 103 8.251e-06 8.826e-05
436 VENTRICULAR SEPTUM MORPHOGENESIS 17 28 8.315e-06 8.874e-05
437 MESONEPHROS DEVELOPMENT 38 90 8.351e-06 8.892e-05
438 NEGATIVE REGULATION OF AXONOGENESIS 30 65 8.826e-06 9.376e-05
439 OUTFLOW TRACT MORPHOGENESIS 27 56 8.988e-06 9.526e-05
440 REGULATION OF CELL CYCLE G2 M PHASE TRANSITION 28 59 9.032e-06 9.552e-05
441 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 90 274 9.218e-06 9.726e-05
442 APOPTOTIC SIGNALING PATHWAY 94 289 9.275e-06 9.764e-05
443 TISSUE MIGRATION 36 84 9.554e-06 0.0001003
444 MAMMARY GLAND DEVELOPMENT 46 117 9.957e-06 0.0001043
445 CELL CYCLE CHECKPOINT 68 194 1.04e-05 0.0001088
446 ACTION POTENTIAL 39 94 1.054e-05 0.0001097
447 NEURAL TUBE FORMATION 39 94 1.054e-05 0.0001097
448 REGULATION OF TRANSPORTER ACTIVITY 69 198 1.124e-05 0.0001168
449 LIPID TRANSLOCATION 14 21 1.137e-05 0.0001176
450 POSITIVE REGULATION OF AUTOPHAGY 33 75 1.135e-05 0.0001176
451 RESPONSE TO IONIZING RADIATION 54 145 1.163e-05 0.00012
452 REGULATION OF RESPONSE TO WOUNDING 126 413 1.171e-05 0.0001201
453 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 47 121 1.171e-05 0.0001201
454 RESPONSE TO NUTRIENT 67 191 1.169e-05 0.0001201
455 SPROUTING ANGIOGENESIS 23 45 1.221e-05 0.0001248
456 DIGESTIVE TRACT MORPHOGENESIS 24 48 1.287e-05 0.0001313
457 RESPONSE TO OXIDATIVE STRESS 110 352 1.301e-05 0.0001324
458 NEURAL TUBE DEVELOPMENT 55 149 1.309e-05 0.0001329
459 SENSORY ORGAN MORPHOGENESIS 80 239 1.311e-05 0.0001329
460 HEART VALVE DEVELOPMENT 19 34 1.321e-05 0.0001332
461 CAMP METABOLIC PROCESS 19 34 1.321e-05 0.0001332
462 MUCOPOLYSACCHARIDE METABOLIC PROCESS 43 108 1.323e-05 0.0001332
463 ARTERY MORPHOGENESIS 25 51 1.331e-05 0.0001337
464 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 112 360 1.36e-05 0.0001363
465 STEROID HORMONE MEDIATED SIGNALING PATHWAY 48 125 1.363e-05 0.0001364
466 REGULATION OF LEUKOCYTE DIFFERENTIATION 78 232 1.398e-05 0.0001396
467 REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 39 95 1.418e-05 0.000141
468 TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 39 95 1.418e-05 0.000141
469 PROTEIN UBIQUITINATION 180 629 1.473e-05 0.0001461
470 MULTICELLULAR ORGANISMAL MACROMOLECULE METABOLIC PROCESS 34 79 1.501e-05 0.0001486
471 REGULATION OF MEMBRANE LIPID DISTRIBUTION 20 37 1.531e-05 0.0001513
472 REGULATION OF HORMONE LEVELS 142 478 1.559e-05 0.0001537
473 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 113 365 1.589e-05 0.0001563
474 STEM CELL DIVISION 17 29 1.605e-05 0.0001572
475 NEUROBLAST PROLIFERATION 17 29 1.605e-05 0.0001572
476 EPITHELIAL CELL PROLIFERATION 37 89 1.664e-05 0.0001627
477 MAMMARY GLAND MORPHOGENESIS 21 40 1.707e-05 0.0001662
478 DEVELOPMENTAL PIGMENTATION 21 40 1.707e-05 0.0001662
479 GLIOGENESIS 62 175 1.715e-05 0.0001666
480 RESPONSE TO INORGANIC SUBSTANCE 142 479 1.751e-05 0.0001697
481 EPITHELIAL CELL DEVELOPMENT 65 186 1.797e-05 0.0001739
482 MUSCLE SYSTEM PROCESS 91 282 1.806e-05 0.0001744
483 CIRCULATORY SYSTEM PROCESS 113 366 1.817e-05 0.0001751
484 REGULATION OF MEMBRANE POTENTIAL 107 343 1.842e-05 0.0001771
485 CYTOSKELETON DEPENDENT INTRACELLULAR TRANSPORT 45 116 1.849e-05 0.0001774
486 REGULATION OF CATION TRANSMEMBRANE TRANSPORT 71 208 1.881e-05 0.0001801
487 ENDOCARDIAL CUSHION DEVELOPMENT 18 32 1.978e-05 0.000189
488 CELLULAR GLUCAN METABOLIC PROCESS 27 58 2.021e-05 0.0001915
489 GLUCAN METABOLIC PROCESS 27 58 2.021e-05 0.0001915
490 REGULATION OF SMOOTH MUSCLE CELL MIGRATION 24 49 2.008e-05 0.0001915
491 NEGATIVE REGULATION OF CELL ACTIVATION 57 158 2.016e-05 0.0001915
492 CIRCADIAN RHYTHM 51 137 2.034e-05 0.0001924
493 CYCLIC NUCLEOTIDE CATABOLIC PROCESS 12 17 2.067e-05 0.0001947
494 NEGATIVE REGULATION OF ANOIKIS 12 17 2.067e-05 0.0001947
495 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 101 321 2.112e-05 0.0001985
496 SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR 48 127 2.223e-05 0.0002086
497 ESTABLISHMENT OR MAINTENANCE OF CELL POLARITY 52 141 2.288e-05 0.0002142
498 CARBOHYDRATE METABOLIC PROCESS 187 662 2.342e-05 0.0002188
499 CELL CELL JUNCTION ASSEMBLY 32 74 2.357e-05 0.0002198
500 REGULATION OF RECEPTOR ACTIVITY 45 117 2.382e-05 0.0002203
501 HIPPO SIGNALING 16 27 2.371e-05 0.0002203
502 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 45 117 2.382e-05 0.0002203
503 CELLULAR RESPONSE TO STARVATION 45 117 2.382e-05 0.0002203
504 POSITIVE REGULATION OF CELL ADHESION 115 376 2.445e-05 0.0002257
505 AMINOGLYCAN BIOSYNTHETIC PROCESS 42 107 2.488e-05 0.0002292
506 CELL CELL SIGNALING INVOLVED IN CARDIAC CONDUCTION 14 22 2.504e-05 0.0002298
507 SOMATIC STEM CELL DIVISION 14 22 2.504e-05 0.0002298
508 NEGATIVE REGULATION OF CELL CELL ADHESION 51 138 2.556e-05 0.0002342
509 POSITIVE REGULATION OF HEMOPOIESIS 58 163 2.728e-05 0.0002493
510 POSITIVE REGULATION OF PROTEIN IMPORT 41 104 2.741e-05 0.0002501
511 CARBOHYDRATE DERIVATIVE BIOSYNTHETIC PROCESS 170 595 2.77e-05 0.0002523
512 AORTA DEVELOPMENT 21 41 2.789e-05 0.0002535
513 VASCULOGENESIS 27 59 2.964e-05 0.0002683
514 REGULATION OF MEMBRANE REPOLARIZATION 17 30 2.959e-05 0.0002683
515 RESPONSE TO ESTROGEN 73 218 3.014e-05 0.0002723
516 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 26 56 3.034e-05 0.000273
517 POSITIVE REGULATION OF NEURON APOPTOTIC PROCESS 23 47 3.033e-05 0.000273
518 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 25 53 3.073e-05 0.0002761
519 CELL CELL SIGNALING 212 767 3.086e-05 0.0002766
520 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 227 829 3.165e-05 0.0002832
521 REGULATION OF CELL CYCLE ARREST 42 108 3.229e-05 0.0002884
522 MYELOID CELL HOMEOSTASIS 36 88 3.267e-05 0.0002912
523 ENDOTHELIAL CELL DIFFERENTIATION 31 72 3.485e-05 0.00031
524 HOMEOSTASIS OF NUMBER OF CELLS 61 175 3.492e-05 0.00031
525 PATTERN SPECIFICATION PROCESS 125 418 3.526e-05 0.0003125
526 REGULATION OF PROTEIN BINDING 59 168 3.631e-05 0.0003212
527 PHOSPHOLIPID METABOLIC PROCESS 111 364 3.853e-05 0.0003402
528 POSITIVE REGULATION OF AXON EXTENSION 19 36 3.898e-05 0.0003428
529 SEMAPHORIN PLEXIN SIGNALING PATHWAY 19 36 3.898e-05 0.0003428
530 REGULATION OF WOUND HEALING 47 126 3.972e-05 0.0003487
531 SMALL MOLECULE METABOLIC PROCESS 448 1767 4.024e-05 0.0003526
532 REGULATION OF MUSCLE ADAPTATION 28 63 4.108e-05 0.0003593
533 DENDRITE DEVELOPMENT 33 79 4.16e-05 0.0003625
534 BONE MORPHOGENESIS 33 79 4.16e-05 0.0003625
535 VESICLE CYTOSKELETAL TRAFFICKING 20 39 4.222e-05 0.0003672
536 REGULATION OF PEPTIDE SECRETION 70 209 4.309e-05 0.0003741
537 NEGATIVE REGULATION OF KINASE ACTIVITY 81 250 4.326e-05 0.0003748
538 RIBONUCLEOTIDE CATABOLIC PROCESS 16 28 4.424e-05 0.0003808
539 CYCLIC NUCLEOTIDE METABOLIC PROCESS 26 57 4.439e-05 0.0003808
540 CIRCADIAN REGULATION OF GENE EXPRESSION 26 57 4.439e-05 0.0003808
541 ENDOTHELIAL CELL MIGRATION 26 57 4.439e-05 0.0003808
542 DENDRITE MORPHOGENESIS 21 42 4.448e-05 0.0003808
543 REGULATED EXOCYTOSIS 74 224 4.446e-05 0.0003808
544 HEMOSTASIS 97 311 4.452e-05 0.0003808
545 SKELETAL MUSCLE ORGAN DEVELOPMENT 50 137 4.467e-05 0.0003814
546 CELL CHEMOTAXIS 57 162 4.59e-05 0.0003897
547 EXOCRINE SYSTEM DEVELOPMENT 22 45 4.584e-05 0.0003897
548 ENDOCHONDRAL BONE MORPHOGENESIS 22 45 4.584e-05 0.0003897
549 POSITIVE REGULATION OF CELL CELL ADHESION 79 243 4.686e-05 0.0003972
550 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 235 867 4.735e-05 0.0004006
551 REGULATION OF CELL SUBSTRATE ADHESION 60 173 4.762e-05 0.0004022
552 REGULATION OF STEM CELL DIFFERENTIATION 43 113 4.814e-05 0.0004058
553 AMINOGLYCAN METABOLIC PROCESS 58 166 4.97e-05 0.0004182
554 PROTEIN TARGETING TO PLASMA MEMBRANE 14 23 5.126e-05 0.0004305
555 ACTIN FILAMENT BASED MOVEMENT 37 93 5.252e-05 0.0004403
556 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 107 351 5.339e-05 0.0004468
557 CELL MATURATION 48 131 5.598e-05 0.0004668
558 PROTEIN STABILIZATION 48 131 5.598e-05 0.0004668
559 POLYSACCHARIDE METABOLIC PROCESS 33 80 5.626e-05 0.0004683
560 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 39 100 5.646e-05 0.0004691
561 REGULATION OF TRANSMEMBRANE TRANSPORT 126 426 5.674e-05 0.0004706
562 REGULATION OF CELL MATRIX ADHESION 36 90 5.765e-05 0.0004773
563 ORGANIC HYDROXY COMPOUND METABOLIC PROCESS 140 482 5.923e-05 0.0004895
564 DEVELOPMENTAL CELL GROWTH 32 77 6.095e-05 0.000502
565 CELLULAR TRANSITION METAL ION HOMEOSTASIS 32 77 6.095e-05 0.000502
566 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 49 135 6.223e-05 0.0005116
567 CELL COMMUNICATION INVOLVED IN CARDIAC CONDUCTION 19 37 6.395e-05 0.0005248
568 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 54 153 6.521e-05 0.0005342
569 ENTRAINMENT OF CIRCADIAN CLOCK 15 26 6.608e-05 0.0005395
570 MESODERMAL CELL DIFFERENTIATION 15 26 6.608e-05 0.0005395
571 PROTEIN COMPLEX SUBUNIT ORGANIZATION 390 1527 6.808e-05 0.0005548
572 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 42 111 6.826e-05 0.0005553
573 GLOMERULUS DEVELOPMENT 23 49 6.967e-05 0.0005657
574 REGULATION OF ION HOMEOSTASIS 67 201 7.319e-05 0.0005933
575 REGULATION OF JUN KINASE ACTIVITY 33 81 7.543e-05 0.0006104
576 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 29 68 7.603e-05 0.0006142
577 REGENERATION 56 161 7.64e-05 0.0006161
578 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 47 129 7.814e-05 0.000629
579 REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 16 29 7.894e-05 0.0006311
580 POSITIVE REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 16 29 7.894e-05 0.0006311
581 PIGMENT CELL DIFFERENTIATION 16 29 7.894e-05 0.0006311
582 CARDIAC MUSCLE CELL CONTRACTION 16 29 7.894e-05 0.0006311
583 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 38 98 8.085e-05 0.0006453
584 RENAL TUBULE DEVELOPMENT 32 78 8.215e-05 0.0006545
585 NON CANONICAL WNT SIGNALING PATHWAY 50 140 8.477e-05 0.0006719
586 REGULATION OF HORMONE SECRETION 83 262 8.452e-05 0.0006719
587 CELLULAR HOMEOSTASIS 187 676 8.464e-05 0.0006719
588 SALIVARY GLAND DEVELOPMENT 17 32 8.929e-05 0.0007042
589 POSITIVE REGULATION OF DENDRITE MORPHOGENESIS 17 32 8.929e-05 0.0007042
590 ADIPOSE TISSUE DEVELOPMENT 17 32 8.929e-05 0.0007042
591 REGULATION OF STRIATED MUSCLE CELL DIFFERENTIATION 34 85 9.151e-05 0.000718
592 HEART PROCESS 34 85 9.151e-05 0.000718
593 CAMP CATABOLIC PROCESS 10 14 9.122e-05 0.000718
594 VESICLE DOCKING 25 56 9.566e-05 0.0007493
595 REGULATION OF ANOIKIS 14 24 9.858e-05 0.0007709
596 PEPTIDYL SERINE MODIFICATION 52 148 0.0001007 0.0007862
597 SYNAPSE ASSEMBLY 29 69 0.0001043 0.0008131
598 NEGATIVE REGULATION OF STRESS ACTIVATED MAPK CASCADE 20 41 0.0001049 0.0008152
599 NEGATIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 20 41 0.0001049 0.0008152
600 MYELOID CELL DEVELOPMENT 21 44 0.0001058 0.0008203
601 LOCOMOTORY BEHAVIOR 61 181 0.000106 0.0008203
602 PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 48 134 0.0001069 0.0008263
603 CELLULAR RESPONSE TO FLUID SHEAR STRESS 12 19 0.0001085 0.0008359
604 VENTRICULAR CARDIAC MUSCLE CELL DIFFERENTIATION 12 19 0.0001085 0.0008359
605 REGULATION OF GENERATION OF PRECURSOR METABOLITES AND ENERGY 35 89 0.0001091 0.000839
606 REGULATION OF CARDIAC MUSCLE CONTRACTION 28 66 0.0001122 0.0008615
607 MYELOID LEUKOCYTE DIFFERENTIATION 37 96 0.0001156 0.0008845
608 SIGNAL TRANSDUCTION IN RESPONSE TO DNA DAMAGE 37 96 0.0001156 0.0008845
609 REGULATION OF AUTOPHAGY 79 249 0.0001169 0.0008931
610 CENTRAL NERVOUS SYSTEM NEURON AXONOGENESIS 15 27 0.000119 0.0009081
611 POSITIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 47 131 0.00012 0.0009127
612 NEGATIVE REGULATION OF BINDING 47 131 0.00012 0.0009127
613 PHOSPHATIDYLINOSITOL METABOLIC PROCESS 64 193 0.0001241 0.0009422
614 PLATELET ACTIVATION 50 142 0.0001274 0.0009657
615 NEPHRON EPITHELIUM DEVELOPMENT 36 93 0.0001281 0.0009676
616 CHONDROCYTE DIFFERENTIATION 26 60 0.0001281 0.0009676
617 NEGATIVE REGULATION OF MAP KINASE ACTIVITY 30 73 0.0001305 0.0009824
618 ERYTHROCYTE HOMEOSTASIS 30 73 0.0001305 0.0009824
619 ORGAN REGENERATION 33 83 0.0001323 0.0009948
620 PEPTIDYL TYROSINE MODIFICATION 62 186 0.0001331 0.0009988
621 PEPTIDYL TYROSINE DEPHOSPHORYLATION 38 100 0.0001334 0.0009997
622 CELLULAR RESPONSE TO ACID CHEMICAL 59 175 0.0001346 0.001007
623 NEGATIVE REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 16 30 0.0001353 0.001008
624 RESPONSE TO X RAY 16 30 0.0001353 0.001008
625 REGULATION OF DENDRITIC SPINE MORPHOGENESIS 16 30 0.0001353 0.001008
626 PROTEIN TARGETING 119 406 0.000136 0.001011
627 LEUKOCYTE ACTIVATION 121 414 0.0001368 0.001015
628 REGULATION OF CYTOKINE PRODUCTION 158 563 0.0001381 0.001023
629 PHOSPHOLIPID BIOSYNTHETIC PROCESS 75 235 0.0001393 0.001031
630 RESPONSE TO INSULIN 67 205 0.0001421 0.00105
631 PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 233 873 0.000143 0.001053
632 INTRACELLULAR RECEPTOR SIGNALING PATHWAY 57 168 0.000143 0.001053
633 RESPONSE TO ORGANOPHOSPHORUS 49 139 0.0001433 0.001054
634 NEGATIVE REGULATION OF JNK CASCADE 17 33 0.0001472 0.001081
635 POSITIVE REGULATION OF FAT CELL DIFFERENTIATION 23 51 0.0001493 0.001092
636 NEGATIVE REGULATION OF CHEMOTAXIS 23 51 0.0001493 0.001092
637 SEX DIFFERENTIATION 83 266 0.0001494 0.001092
638 RESPONSE TO CAMP 39 104 0.0001523 0.001111
639 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 22 48 0.0001545 0.001122
640 POSITIVE REGULATION OF RESPONSE TO EXTRACELLULAR STIMULUS 22 48 0.0001545 0.001122
641 POSITIVE REGULATION OF RESPONSE TO NUTRIENT LEVELS 22 48 0.0001545 0.001122
642 REGULATION OF PLATELET AGGREGATION 11 17 0.0001558 0.001127
643 REGULATION OF PRI MIRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 11 17 0.0001558 0.001127
644 TRABECULA MORPHOGENESIS 19 39 0.000159 0.001149
645 RESPONSE TO STARVATION 53 154 0.0001597 0.001152
646 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 75 236 0.0001617 0.001163
647 POSITIVE REGULATION OF ION TRANSPORT 75 236 0.0001617 0.001163
648 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 160 573 0.000164 0.001175
649 LEUKOCYTE MIGRATION 81 259 0.0001641 0.001175
650 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 110 372 0.000164 0.001175
651 RESPONSE TO CALCIUM ION 42 115 0.0001719 0.001229
652 CYTOKINESIS 33 84 0.0001733 0.001237
653 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 45 126 0.0001867 0.001331
654 CELLULAR CARBOHYDRATE METABOLIC PROCESS 50 144 0.0001887 0.001343
655 SKIN EPIDERMIS DEVELOPMENT 29 71 0.0001906 0.001354
656 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 145 514 0.0001975 0.001401
657 EPIDERMAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 24 55 0.000202 0.001429
658 CRANIAL SKELETAL SYSTEM DEVELOPMENT 24 55 0.000202 0.001429
659 REGULATION OF COAGULATION 34 88 0.0002032 0.001434
660 MAMMARY GLAND DUCT MORPHOGENESIS 15 28 0.0002054 0.001448
661 RESPONSE TO ACID CHEMICAL 96 319 0.0002098 0.001468
662 POSITIVE REGULATION OF MITOTIC CELL CYCLE 44 123 0.0002098 0.001468
663 ORGANOPHOSPHATE BIOSYNTHETIC PROCESS 129 450 0.0002094 0.001468
664 CHROMATIN MODIFICATION 151 539 0.0002096 0.001468
665 GOLGI VESICLE TRANSPORT 96 319 0.0002098 0.001468
666 CANONICAL WNT SIGNALING PATHWAY 36 95 0.000211 0.001474
667 ORGANIC ACID TRANSPORT 81 261 0.0002165 0.001508
668 INTRINSIC APOPTOTIC SIGNALING PATHWAY 52 152 0.0002168 0.001508
669 POSITIVE REGULATION OF WNT SIGNALING PATHWAY 52 152 0.0002168 0.001508
670 N GLYCAN PROCESSING 12 20 0.0002179 0.001514
671 AMINO ACID IMPORT 10 15 0.0002205 0.001529
672 REGULATION OF PLATELET ACTIVATION 16 31 0.0002238 0.001548
673 CARDIAC CELL DEVELOPMENT 22 49 0.0002237 0.001548
674 POSITIVE REGULATION OF PROTEOLYSIS 107 363 0.0002278 0.001573
675 PROTEIN N LINKED GLYCOSYLATION 30 75 0.0002314 0.001595
676 PEPTIDYL THREONINE MODIFICATION 21 46 0.0002323 0.001599
677 MACROMOLECULE CATABOLIC PROCESS 244 926 0.0002347 0.001613
678 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 64 197 0.0002387 0.001638
679 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 48 138 0.0002394 0.001641
680 CARDIAC VENTRICLE MORPHOGENESIS 26 62 0.0002438 0.001668
681 REGULATION OF EXOCYTOSIS 61 186 0.0002478 0.001693
682 MODULATION OF SYNAPTIC TRANSMISSION 91 301 0.0002541 0.001734
683 METAL ION TRANSPORT 161 582 0.000255 0.001737
684 AMINO ACID TRANSPORT 44 124 0.0002581 0.001756
685 CELLULAR CHEMICAL HOMEOSTASIS 158 570 0.0002615 0.001776
686 REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 25 59 0.0002627 0.001782
687 RESPONSE TO METAL ION 99 333 0.000274 0.001856
688 RESPONSE TO ESTRADIOL 50 146 0.0002755 0.001858
689 CELLULAR RESPONSE TO INSULIN STIMULUS 50 146 0.0002755 0.001858
690 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 68 213 0.0002748 0.001858
691 HEPATICOBILIARY SYSTEM DEVELOPMENT 45 128 0.0002808 0.001888
692 MUSCLE CELL DEVELOPMENT 45 128 0.0002808 0.001888
693 REGULATION OF DENDRITIC SPINE DEVELOPMENT 24 56 0.0002818 0.001892
694 REGULATION OF PROTEIN SECRETION 113 389 0.0002892 0.001939
695 REGULATION OF DNA BINDING 35 93 0.0002993 0.002004
696 MAMMARY GLAND EPITHELIUM DEVELOPMENT 23 53 0.0003006 0.00201
697 REGULATION OF CALCIUM MEDIATED SIGNALING 30 76 0.0003042 0.002028
698 MULTICELLULAR ORGANISM GROWTH 30 76 0.0003042 0.002028
699 NEURONAL STEM CELL DIVISION 9 13 0.0003055 0.002031
700 NEUROBLAST DIVISION 9 13 0.0003055 0.002031
701 LIPID MODIFICATION 67 210 0.0003095 0.002054
702 POST GOLGI VESICLE MEDIATED TRANSPORT 32 83 0.0003226 0.002129
703 POSITIVE REGULATION OF MITOCHONDRIAL MEMBRANE PERMEABILITY 11 18 0.0003224 0.002129
704 PROTEOGLYCAN METABOLIC PROCESS 32 83 0.0003226 0.002129
705 OSTEOBLAST DEVELOPMENT 11 18 0.0003224 0.002129
706 CELLULAR RESPONSE TO KETONE 29 73 0.0003353 0.00221
707 REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 15 29 0.0003408 0.002237
708 REGULATION OF VACUOLAR TRANSPORT 15 29 0.0003408 0.002237
709 POSITIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 15 29 0.0003408 0.002237
710 CELLULAR RESPONSE TO CYTOKINE STIMULUS 166 606 0.0003435 0.00225
711 RESPONSE TO LIGHT STIMULUS 85 280 0.0003439 0.00225
712 REGULATION OF APOPTOTIC SIGNALING PATHWAY 106 363 0.0003554 0.002322
713 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 43 122 0.0003559 0.002323
714 ORGANELLE TRANSPORT ALONG MICROTUBULE 25 60 0.0003589 0.002335
715 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 25 60 0.0003589 0.002335
716 NEGATIVE REGULATION OF AXON EXTENSION 18 38 0.0003664 0.002375
717 SUBSTRATE ADHESION DEPENDENT CELL SPREADING 18 38 0.0003664 0.002375
718 MESENCHYME MORPHOGENESIS 18 38 0.0003664 0.002375
719 ORGANONITROGEN COMPOUND METABOLIC PROCESS 445 1796 0.0003679 0.002381
720 COENZYME METABOLIC PROCESS 81 265 0.0003692 0.002386
721 HINDBRAIN DEVELOPMENT 47 137 0.0003949 0.002549
722 REGULATION OF BMP SIGNALING PATHWAY 30 77 0.0003966 0.002553
723 MALE SEX DIFFERENTIATION 50 148 0.0003967 0.002553
724 CELLULAR CATABOLIC PROCESS 335 1322 0.0004051 0.0026
725 POSITIVE REGULATION OF NEURON DEATH 27 67 0.0004051 0.0026
726 B CELL HOMEOSTASIS 12 21 0.0004087 0.002602
727 CHONDROCYTE DEVELOPMENT 12 21 0.0004087 0.002602
728 RESPONSE TO FOLLICLE STIMULATING HORMONE 8 11 0.0004089 0.002602
729 GLYCEROPHOSPHOLIPID METABOLIC PROCESS 89 297 0.0004073 0.002602
730 PROTEIN DEGLYCOSYLATION 12 21 0.0004087 0.002602
731 CELLULAR RESPONSE TO OSMOTIC STRESS 12 21 0.0004087 0.002602
732 PROTEIN POLYUBIQUITINATION 75 243 0.0004343 0.002757
733 RESPONSE TO KETONE 59 182 0.0004343 0.002757
734 COVALENT CHROMATIN MODIFICATION 101 345 0.0004376 0.002774
735 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 29 74 0.0004389 0.002779
736 ION HOMEOSTASIS 158 576 0.0004403 0.002784
737 NEGATIVE REGULATION OF RESPONSE TO WOUNDING 52 156 0.0004426 0.002794
738 REGULATION OF PHOSPHOLIPASE ACTIVITY 26 64 0.0004437 0.002797
739 METANEPHROS DEVELOPMENT 31 81 0.0004613 0.002901
740 CELLULAR COMPONENT DISASSEMBLY 143 515 0.000461 0.002901
741 RESPONSE TO HYDROGEN PEROXIDE 39 109 0.0004645 0.002917
742 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 66 209 0.0004682 0.002932
743 LYMPHOCYTE DIFFERENTIATION 66 209 0.0004682 0.002932
744 POSITIVE REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 13 24 0.0004746 0.002952
745 RESPONSE TO STEROL 13 24 0.0004746 0.002952
746 REGULATION OF LIPID KINASE ACTIVITY 21 48 0.0004758 0.002952
747 POSITIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 13 24 0.0004746 0.002952
748 NEGATIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 13 24 0.0004746 0.002952
749 PLACENTA DEVELOPMENT 47 138 0.0004752 0.002952
750 REGULATION OF CATION CHANNEL ACTIVITY 33 88 0.0004735 0.002952
751 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 116 406 0.0004866 0.003015
752 LYMPHOCYTE ACTIVATION 100 342 0.0004876 0.003017
753 REGULATION OF MYELOID CELL DIFFERENTIATION 59 183 0.000508 0.003139
754 VACUOLE ORGANIZATION 55 168 0.0005095 0.003144
755 NEGATIVE REGULATION OF AXON GUIDANCE 14 27 0.0005198 0.003203
756 INOSITOL LIPID MEDIATED SIGNALING 43 124 0.000528 0.00325
757 REGULATION OF CARBOHYDRATE METABOLIC PROCESS 56 172 0.000531 0.003264
758 STRIATED MUSCLE CONTRACTION 36 99 0.0005318 0.003264
759 RESPONSE TO TUMOR NECROSIS FACTOR 72 233 0.0005376 0.003295
760 DIVALENT INORGANIC CATION TRANSPORT 81 268 0.0005418 0.003317
761 SMOOTH MUSCLE CELL DIFFERENTIATION 15 30 0.0005463 0.003327
762 REGULATION OF CELL ADHESION MEDIATED BY INTEGRIN 18 39 0.0005442 0.003327
763 REGULATION OF HEART RATE BY CARDIAC CONDUCTION 15 30 0.0005463 0.003327
764 OSTEOCLAST DIFFERENTIATION 15 30 0.0005463 0.003327
765 CELLULAR RESPONSE TO HEAT 17 36 0.0005555 0.00337
766 POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 17 36 0.0005555 0.00337
767 REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 17 36 0.0005555 0.00337
768 NEURON RECOGNITION 16 33 0.0005572 0.003371
769 EMBRYONIC DIGESTIVE TRACT DEVELOPMENT 16 33 0.0005572 0.003371
770 REGULATION OF CIRCADIAN RHYTHM 37 103 0.0005874 0.00355
771 CELLULAR RESPONSE TO OXIDATIVE STRESS 59 184 0.0005928 0.003578
772 ORGANOPHOSPHATE ESTER TRANSPORT 33 89 0.0005986 0.003608
773 REGULATION OF LYMPHOCYTE DIFFERENTIATION 45 132 0.0006049 0.003641
774 GLYCEROLIPID METABOLIC PROCESS 103 356 0.0006087 0.003655
775 POSITIVE REGULATION OF MAP KINASE ACTIVITY 65 207 0.0006087 0.003655
776 ENTRAINMENT OF CIRCADIAN CLOCK BY PHOTOPERIOD 11 19 0.0006164 0.003696
777 HORMONE MEDIATED SIGNALING PATHWAY 52 158 0.0006206 0.003717
778 POSITIVE REGULATION OF ENDOCYTOSIS 40 114 0.0006215 0.003717
779 MACROAUTOPHAGY 84 281 0.0006319 0.003775
780 REGULATION OF MUSCLE CONTRACTION 49 147 0.0006361 0.003794
781 GLIAL CELL DIFFERENTIATION 46 136 0.0006431 0.003826
782 EYE MORPHOGENESIS 46 136 0.0006431 0.003826
783 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 25 62 0.0006474 0.003847
784 NEGATIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 53 162 0.0006484 0.003848
785 REGULATION OF STRIATED MUSCLE CONTRACTION 30 79 0.0006583 0.003897
786 ERBB SIGNALING PATHWAY 30 79 0.0006583 0.003897
787 POSITIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 78 258 0.000672 0.003973
788 CHONDROITIN SULFATE CATABOLIC PROCESS 9 14 0.0006912 0.004066
789 POSITIVE REGULATION OF CELL SIZE 9 14 0.0006912 0.004066
790 POSITIVE REGULATION OF DENDRITIC SPINE MORPHOGENESIS 9 14 0.0006912 0.004066
791 RESPONSE TO LAMINAR FLUID SHEAR STRESS 9 14 0.0006912 0.004066
792 PROTEIN OLIGOMERIZATION 122 434 0.0007021 0.004125
793 CYCLIC NUCLEOTIDE MEDIATED SIGNALING 20 46 0.0007102 0.004167
794 NEGATIVE REGULATION OF REGULATED SECRETORY PATHWAY 12 22 0.0007231 0.004232
795 CENTRAL NERVOUS SYSTEM PROJECTION NEURON AXONOGENESIS 12 22 0.0007231 0.004232
796 POSITIVE REGULATION OF TRANSPORTER ACTIVITY 29 76 0.0007336 0.004277
797 EXTRACELLULAR MATRIX DISASSEMBLY 29 76 0.0007336 0.004277
798 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 67 216 0.000733 0.004277
799 POSITIVE REGULATION OF CATION TRANSMEMBRANE TRANSPORT 35 97 0.0007426 0.004325
800 CALCIUM MEDIATED SIGNALING 33 90 0.0007518 0.004353
801 EMBRYONIC PLACENTA DEVELOPMENT 31 83 0.0007497 0.004353
802 REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 19 43 0.0007531 0.004353
803 MORPHOGENESIS OF AN EPITHELIAL SHEET 19 43 0.0007531 0.004353
804 REGULATION OF LIPASE ACTIVITY 31 83 0.0007497 0.004353
805 CHONDROITIN SULFATE PROTEOGLYCAN METABOLIC PROCESS 19 43 0.0007531 0.004353
806 CELLULAR RESPONSE TO RADIATION 46 137 0.0007685 0.004436
807 INOSITOL PHOSPHATE METABOLIC PROCESS 23 56 0.0007753 0.004465
808 FOREBRAIN GENERATION OF NEURONS 26 66 0.0007749 0.004465
809 REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 38 108 0.0007894 0.00454
810 REGULATION OF TRANSFORMING GROWTH FACTOR BETA PRODUCTION 13 25 0.0007943 0.004546
811 ENDODERMAL CELL DIFFERENTIATION 18 40 0.0007915 0.004546
812 HISTONE PHOSPHORYLATION 13 25 0.0007943 0.004546
813 PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 13 25 0.0007943 0.004546
814 TRANSMEMBRANE TRANSPORT 280 1098 0.0007977 0.00456
815 REGULATION OF CALCIUM ION TRANSPORT 65 209 0.0008069 0.004607
816 ION TRANSMEMBRANE TRANSPORT 215 822 0.0008165 0.004656
817 POSITIVE REGULATION OF CATION CHANNEL ACTIVITY 17 37 0.0008226 0.004679
818 REGULATION OF MUSCLE HYPERTROPHY 17 37 0.0008226 0.004679
819 REGIONALIZATION 91 311 0.0008291 0.004711
820 NEGATIVE REGULATION OF EXOCYTOSIS 14 28 0.0008342 0.00472
821 REGULATION OF DNA DAMAGE RESPONSE SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR 14 28 0.0008342 0.00472
822 RESPONSE TO BMP 34 94 0.0008349 0.00472
823 CELLULAR RESPONSE TO BMP STIMULUS 34 94 0.0008349 0.00472
824 NEGATIVE REGULATION OF VASCULATURE DEVELOPMENT 30 80 0.0008385 0.004735
825 PLATELET DERIVED GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 16 34 0.0008431 0.004739
826 POSITIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 16 34 0.0008431 0.004739
827 ADHERENS JUNCTION ASSEMBLY 16 34 0.0008431 0.004739
828 TISSUE REMODELING 32 87 0.0008434 0.004739
829 REGULATION OF CARTILAGE DEVELOPMENT 25 63 0.0008558 0.004781
830 REGULATION OF PROTEIN STABILITY 68 221 0.0008558 0.004781
831 NEUROEPITHELIAL CELL DIFFERENTIATION 25 63 0.0008558 0.004781
832 POSITIVE REGULATION OF JUN KINASE ACTIVITY 25 63 0.0008558 0.004781
833 RESPONSE TO OSMOTIC STRESS 25 63 0.0008558 0.004781
834 LIPID LOCALIZATION 79 264 0.0008694 0.004851
835 NUCLEOBASE CONTAINING SMALL MOLECULE METABOLIC PROCESS 146 535 0.0008952 0.004989
836 MUSCLE CONTRACTION 71 233 0.0008981 0.004999
837 REGULATION OF MEMBRANE PERMEABILITY 27 70 0.0009086 0.005051
838 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 87 296 0.0009151 0.005071
839 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 21 50 0.0009155 0.005071
840 ENDODERM FORMATION 21 50 0.0009155 0.005071
841 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 35 98 0.0009187 0.005083
842 REGULATION OF SKELETAL MUSCLE CELL DIFFERENTIATION 10 17 0.0009289 0.005103
843 NEGATIVE REGULATION OF PLATELET ACTIVATION 10 17 0.0009289 0.005103
844 REGULATION OF ENERGY HOMEOSTASIS 10 17 0.0009289 0.005103
845 REGULATION OF GLUCOSE IMPORT IN RESPONSE TO INSULIN STIMULUS 10 17 0.0009289 0.005103
846 REGULATION OF CALCINEURIN NFAT SIGNALING CASCADE 10 17 0.0009289 0.005103
847 FILOPODIUM ASSEMBLY 10 17 0.0009289 0.005103
848 CELLULAR LIPID METABOLIC PROCESS 236 913 0.0009348 0.005129
849 ACTOMYOSIN STRUCTURE ORGANIZATION 29 77 0.0009372 0.005136
850 POSITIVE REGULATION OF MUSCLE CELL DIFFERENTIATION 31 84 0.0009458 0.005177
851 LEARNING 44 131 0.0009798 0.005357
852 PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROCESS 41 120 0.0009818 0.005362
853 POSITIVE REGULATION OF ORGANELLE ASSEMBLY 20 47 0.000988 0.005389
854 CARTILAGE MORPHOGENESIS 8 12 0.0009938 0.005408
855 CELLULAR RESPONSE TO CHOLESTEROL 8 12 0.0009938 0.005408
856 PROTEIN COMPLEX BIOGENESIS 287 1132 0.001003 0.00544
857 NEGATIVE REGULATION OF HOMOTYPIC CELL CELL ADHESION 36 102 0.001003 0.00544
858 PROTEIN COMPLEX ASSEMBLY 287 1132 0.001003 0.00544
859 REGULATION OF DNA TEMPLATED TRANSCRIPTION IN RESPONSE TO STRESS 26 67 0.001009 0.005468
860 CARBOHYDRATE TRANSPORT 34 95 0.001034 0.005589
861 POLYOL METABOLIC PROCESS 34 95 0.001034 0.005589
862 ORGANOPHOSPHATE CATABOLIC PROCESS 39 113 0.001036 0.005594
863 NEGATIVE REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 32 88 0.001055 0.005687
864 INTERSPECIES INTERACTION BETWEEN ORGANISMS 176 662 0.001074 0.005778
865 SYMBIOSIS ENCOMPASSING MUTUALISM THROUGH PARASITISM 176 662 0.001074 0.005778
866 AUTOPHAGY 111 394 0.001093 0.005871
867 POSITIVE REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 60 192 0.001098 0.005895
868 NUCLEUS LOCALIZATION 11 20 0.001103 0.005895
869 TRACHEA DEVELOPMENT 11 20 0.001103 0.005895
870 REGULATION OF MACROPHAGE DIFFERENTIATION 11 20 0.001103 0.005895
871 MELANOCYTE DIFFERENTIATION 11 20 0.001103 0.005895
872 NEGATIVE REGULATION OF FAT CELL DIFFERENTIATION 18 41 0.001129 0.006024
873 LIPID PHOSPHORYLATION 35 99 0.00113 0.006024
874 REGULATION OF LYMPHOCYTE APOPTOTIC PROCESS 22 54 0.001137 0.006042
875 REGULATION OF DEPHOSPHORYLATION 51 158 0.001137 0.006042
876 NEGATIVE REGULATION OF INTRACELLULAR TRANSPORT 47 143 0.001137 0.006042
877 NEGATIVE REGULATION OF SECRETION 62 200 0.001147 0.006088
878 MITOCHONDRIAL MEMBRANE ORGANIZATION 33 92 0.001164 0.006157
879 REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 33 92 0.001164 0.006157
880 INNER EAR MORPHOGENESIS 33 92 0.001164 0.006157
881 NEGATIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 27 71 0.001168 0.006164
882 ENDODERM DEVELOPMENT 27 71 0.001168 0.006164
883 EPHRIN RECEPTOR SIGNALING PATHWAY 31 85 0.001185 0.006245
884 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 17 38 0.001192 0.006267
885 POSITIVE REGULATION OF ORGAN GROWTH 17 38 0.001192 0.006267
886 TRABECULA FORMATION 12 23 0.001216 0.006388
887 POSITIVE REGULATION OF HOMEOSTATIC PROCESS 66 216 0.001232 0.006463
888 REGULATION OF PROTEIN TYROSINE KINASE ACTIVITY 24 61 0.001241 0.006487
889 REGULATION OF PHOSPHOLIPID METABOLIC PROCESS 24 61 0.001241 0.006487
890 POSITIVE REGULATION OF STEM CELL PROLIFERATION 24 61 0.001241 0.006487
891 POSITIVE REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 21 51 0.001243 0.006493
892 SULFUR COMPOUND METABOLIC PROCESS 102 359 0.001255 0.006546
893 REPLACEMENT OSSIFICATION 13 26 0.001277 0.006629
894 GOLGI TO PLASMA MEMBRANE PROTEIN TRANSPORT 13 26 0.001277 0.006629
895 HEART GROWTH 13 26 0.001277 0.006629
896 ENDOCHONDRAL OSSIFICATION 13 26 0.001277 0.006629
897 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 70 232 0.0013 0.006742
898 MEMBRANE DOCKING 26 68 0.001303 0.006752
899 JNK CASCADE 30 82 0.001332 0.006891
900 MESODERM DEVELOPMENT 40 118 0.001333 0.006891
901 PHOSPHOLIPID TRANSPORT 23 58 0.001372 0.007078
902 VASCULAR PROCESS IN CIRCULATORY SYSTEM 52 163 0.001372 0.007078
903 POSITIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 35 100 0.001383 0.007127
904 CELL PROJECTION ASSEMBLY 78 264 0.001389 0.007147
905 CELL MIGRATION INVOLVED IN SPROUTING ANGIOGENESIS 9 15 0.001397 0.00716
906 REGULATION OF HEAT GENERATION 9 15 0.001397 0.00716
907 CELLULAR RESPONSE TO STEROL 9 15 0.001397 0.00716
908 RESPONSE TO TEMPERATURE STIMULUS 48 148 0.001395 0.00716
909 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 41 122 0.001412 0.007229
910 REGULATION OF NEUROTRANSMITTER LEVELS 59 190 0.001422 0.007267
911 GENERATION OF PRECURSOR METABOLITES AND ENERGY 85 292 0.001423 0.007267
912 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 49 152 0.001447 0.007385
913 RESPONSE TO ALKALOID 45 137 0.00145 0.007392
914 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 54 171 0.001455 0.007405
915 LUNG MORPHOGENESIS 19 45 0.001467 0.007461
916 RESPONSE TO ENDOPLASMIC RETICULUM STRESS 70 233 0.001472 0.007479
917 REGULATION OF HEART RATE 31 86 0.001476 0.007487
918 REGULATION OF LEUKOCYTE APOPTOTIC PROCESS 29 79 0.001496 0.007573
919 NEGATIVE REGULATION OF PROTEIN BINDING 29 79 0.001496 0.007573
920 REGULATION OF ACTIN FILAMENT LENGTH 50 156 0.001498 0.007578
921 REGULATION OF MYOTUBE DIFFERENTIATION 22 55 0.001514 0.007649
922 ESTABLISHMENT OF LOCALIZATION BY MOVEMENT ALONG MICROTUBULE 34 97 0.001561 0.007877
923 CATECHOLAMINE METABOLIC PROCESS 18 42 0.001581 0.007954
924 REGULATION OF HEART GROWTH 18 42 0.001581 0.007954
925 CATECHOL CONTAINING COMPOUND METABOLIC PROCESS 18 42 0.001581 0.007954
926 PURINE CONTAINING COMPOUND METABOLIC PROCESS 110 394 0.001603 0.008056
927 FOREBRAIN CELL MIGRATION 24 62 0.001616 0.008109
928 RESPONSE TO MITOCHONDRIAL DEPOLARISATION 44 134 0.001638 0.008198
929 MITOPHAGY IN RESPONSE TO MITOCHONDRIAL DEPOLARIZATION 44 134 0.001638 0.008198
930 MACROMITOPHAGY 44 134 0.001638 0.008198
931 PERIPHERAL NERVOUS SYSTEM DEVELOPMENT 26 69 0.001667 0.008325
932 IRON ION HOMEOSTASIS 26 69 0.001667 0.008325
933 NEGATIVE REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 17 39 0.001692 0.008386
934 REGULATION OF PHOSPHOLIPASE C ACTIVITY 17 39 0.001692 0.008386
935 WNT SIGNALING PATHWAY CALCIUM MODULATING PATHWAY 17 39 0.001692 0.008386
936 SULFUR COMPOUND CATABOLIC PROCESS 17 39 0.001692 0.008386
937 INOSITOL PHOSPHATE MEDIATED SIGNALING 10 18 0.001687 0.008386
938 NEGATIVE CHEMOTAXIS 17 39 0.001692 0.008386
939 CYTOSKELETON DEPENDENT CYTOKINESIS 17 39 0.001692 0.008386
940 PROTEIN TARGETING TO MEMBRANE 50 157 0.001745 0.008638
941 NEGATIVE REGULATION OF CYTOKINE PRODUCTION 64 211 0.001767 0.008738
942 NEUROMUSCULAR JUNCTION DEVELOPMENT 16 36 0.001796 0.008832
943 NEGATIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 16 36 0.001796 0.008832
944 CELL DIFFERENTIATION INVOLVED IN KIDNEY DEVELOPMENT 16 36 0.001796 0.008832
945 LAMELLIPODIUM ORGANIZATION 16 36 0.001796 0.008832
946 CYTOSOLIC TRANSPORT 65 215 0.001789 0.008832
947 ODONTOGENESIS 36 105 0.001805 0.008869
948 ADULT LOCOMOTORY BEHAVIOR 29 80 0.001869 0.009166
949 NEGATIVE REGULATION OF ORGAN GROWTH 11 21 0.001868 0.009166
950 G2 DNA DAMAGE CHECKPOINT 15 33 0.001884 0.00923
951 ADULT BEHAVIOR 44 135 0.001931 0.009438
952 NEGATIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 44 135 0.001931 0.009438
953 NEURON MATURATION 14 30 0.00195 0.009459
954 NEGATIVE REGULATION OF CELL MATRIX ADHESION 14 30 0.00195 0.009459
955 SIGNAL RELEASE 54 173 0.001941 0.009459
956 POSITIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION 14 30 0.00195 0.009459
957 IMMUNE RESPONSE REGULATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 92 323 0.001939 0.009459
958 CELLULAR RESPONSE TO VASCULAR ENDOTHELIAL GROWTH FACTOR STIMULUS 14 30 0.00195 0.009459
959 LAMELLIPODIUM ASSEMBLY 14 30 0.00195 0.009459
960 PHOTOPERIODISM 12 24 0.001958 0.009471
961 BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 12 24 0.001958 0.009471
962 POSITIVE REGULATION OF CELL ACTIVATION 89 311 0.001955 0.009471
963 POSITIVE REGULATION OF HEART GROWTH 13 27 0.001979 0.009504
964 REGULATION OF CARDIAC MUSCLE CELL CONTRACTION 13 27 0.001979 0.009504
965 CELL CYCLE ARREST 49 154 0.001968 0.009504
966 CELL PROLIFERATION IN FOREBRAIN 13 27 0.001979 0.009504
967 MOTOR NEURON AXON GUIDANCE 13 27 0.001979 0.009504
968 GOLGI TO VACUOLE TRANSPORT 13 27 0.001979 0.009504
969 REGULATION OF CATENIN IMPORT INTO NUCLEUS 13 27 0.001979 0.009504
970 EMBRYONIC CRANIAL SKELETON MORPHOGENESIS 19 46 0.002 0.009594
971 RENAL SYSTEM PROCESS 35 102 0.00204 0.009775
972 REGULATION OF VASCULOGENESIS 8 13 0.002095 0.009967
973 PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 8 13 0.002095 0.009967
974 TRANSEPITHELIAL TRANSPORT 8 13 0.002095 0.009967
975 MITOTIC G2 DNA DAMAGE CHECKPOINT 8 13 0.002095 0.009967
976 POSITIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 68 228 0.002087 0.009967
977 REGULATION OF CELL COMMUNICATION BY ELECTRICAL COUPLING 8 13 0.002095 0.009967
978 SEMAPHORIN PLEXIN SIGNALING PATHWAY INVOLVED IN NEURON PROJECTION GUIDANCE 8 13 0.002095 0.009967
979 REGULATION OF SODIUM ION TRANSPORT 28 77 0.002104 0.009999
NumGOOverlapSizeP ValueAdj. P Value
1 ENZYME BINDING 605 1737 1.108e-40 1.03e-37
2 RIBONUCLEOTIDE BINDING 569 1860 8.25e-22 3.832e-19
3 CYTOSKELETAL PROTEIN BINDING 286 819 2.241e-19 6.939e-17
4 MACROMOLECULAR COMPLEX BINDING 437 1399 1.583e-18 3.676e-16
5 KINASE ACTIVITY 286 842 1.683e-17 3.127e-15
6 KINASE BINDING 220 606 2.768e-17 3.829e-15
7 ADENYL NUCLEOTIDE BINDING 461 1514 2.885e-17 3.829e-15
8 MOLECULAR FUNCTION REGULATOR 414 1353 6.186e-16 7.184e-14
9 PROTEIN KINASE ACTIVITY 224 640 1.579e-15 1.432e-13
10 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 221 629 1.525e-15 1.432e-13
11 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 134 328 1.695e-15 1.432e-13
12 REGULATORY REGION NUCLEIC ACID BINDING 271 818 4.105e-15 3.178e-13
13 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 368 1199 1.867e-14 1.272e-12
14 PROTEIN DOMAIN SPECIFIC BINDING 216 624 1.916e-14 1.272e-12
15 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 314 992 2.411e-14 1.493e-12
16 PROTEIN COMPLEX BINDING 297 935 7.842e-14 4.553e-12
17 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 123 315 1.09e-12 5.958e-11
18 DOUBLE STRANDED DNA BINDING 247 764 1.388e-12 7.162e-11
19 TRANSCRIPTION FACTOR BINDING 182 524 1.618e-12 7.91e-11
20 SEQUENCE SPECIFIC DNA BINDING 313 1037 1.761e-11 8.18e-10
21 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 93 226 2.131e-11 9.429e-10
22 PROTEIN SERINE THREONINE KINASE ACTIVITY 156 445 2.868e-11 1.211e-09
23 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 115 303 4.89e-11 1.975e-09
24 IDENTICAL PROTEIN BINDING 353 1209 8.374e-11 3.242e-09
25 RECEPTOR BINDING 418 1476 1.329e-10 4.939e-09
26 ACTIN BINDING 138 393 3.483e-10 1.199e-08
27 ENZYME REGULATOR ACTIVITY 287 959 3.449e-10 1.199e-08
28 PROTEIN DIMERIZATION ACTIVITY 333 1149 7.519e-10 2.495e-08
29 GTPASE BINDING 109 295 9.522e-10 3.05e-08
30 CORE PROMOTER BINDING 66 152 1.205e-09 3.731e-08
31 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 89 228 1.435e-09 4.302e-08
32 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 188 588 1.867e-09 5.421e-08
33 HISTONE DEACETYLASE BINDING 50 105 2.792e-09 7.859e-08
34 NUCLEOSIDE TRIPHOSPHATASE REGULATOR ACTIVITY 117 329 3.26e-09 8.908e-08
35 PHOSPHORIC ESTER HYDROLASE ACTIVITY 127 368 5.851e-09 1.553e-07
36 ZINC ION BINDING 327 1155 1.652e-08 4.264e-07
37 CORE PROMOTER PROXIMAL REGION DNA BINDING 126 371 1.97e-08 4.945e-07
38 SMAD BINDING 37 72 2.479e-08 6.06e-07
39 UBIQUITIN LIKE PROTEIN LIGASE BINDING 95 264 4.964e-08 1.183e-06
40 PROTEIN HOMODIMERIZATION ACTIVITY 216 722 5.746e-08 1.335e-06
41 ENZYME ACTIVATOR ACTIVITY 151 471 6.018e-08 1.364e-06
42 RECEPTOR SIGNALING PROTEIN ACTIVITY 68 172 6.672e-08 1.476e-06
43 CORE PROMOTER SEQUENCE SPECIFIC DNA BINDING 45 101 2.013e-07 4.349e-06
44 UBIQUITIN LIKE PROTEIN TRANSFERASE ACTIVITY 134 420 4.446e-07 9.387e-06
45 UBIQUITIN LIKE PROTEIN CONJUGATING ENZYME BINDING 21 34 4.72e-07 9.745e-06
46 TRANSITION METAL ION BINDING 377 1400 4.962e-07 1.002e-05
47 CALCIUM ION BINDING 204 697 7.597e-07 1.502e-05
48 BETA CATENIN BINDING 38 84 1.097e-06 2.122e-05
49 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 37 81 1.13e-06 2.141e-05
50 ION CHANNEL BINDING 46 111 1.841e-06 3.42e-05
51 TUBULIN BINDING 92 273 2.232e-06 4.066e-05
52 RHO GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 35 77 2.512e-06 4.404e-05
53 GUANYL NUCLEOTIDE BINDING 123 390 2.492e-06 4.404e-05
54 STEROID HORMONE RECEPTOR ACTIVITY 29 59 2.58e-06 4.438e-05
55 SH3 DOMAIN BINDING 47 116 3.037e-06 5.129e-05
56 PHOSPHOLIPID TRANSPORTER ACTIVITY 25 48 3.299e-06 5.473e-05
57 ACTIVATING TRANSCRIPTION FACTOR BINDING 28 57 3.885e-06 6.332e-05
58 CELL ADHESION MOLECULE BINDING 67 186 4.222e-06 6.762e-05
59 PHOSPHOLIPID BINDING 114 360 4.63e-06 7.29e-05
60 PROTEIN TYROSINE KINASE ACTIVITY 64 176 4.789e-06 7.337e-05
61 HYDROLASE ACTIVITY ACTING ON ACID ANHYDRIDES 230 820 4.818e-06 7.337e-05
62 MICROTUBULE BINDING 71 201 4.936e-06 7.396e-05
63 RECEPTOR SIGNALING PROTEIN SERINE THREONINE KINASE ACTIVITY 39 92 5.688e-06 8.257e-05
64 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 43 105 5.679e-06 8.257e-05
65 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 30 64 5.981e-06 8.419e-05
66 PHOSPHATASE ACTIVITY 91 275 5.894e-06 8.419e-05
67 PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 64 178 7.337e-06 0.0001017
68 GROWTH FACTOR BINDING 48 123 8.193e-06 0.0001119
69 LIPID BINDING 188 657 9.625e-06 0.0001296
70 CHROMATIN BINDING 132 435 9.865e-06 0.0001309
71 TRANSCRIPTION FACTOR ACTIVITY DIRECT LIGAND REGULATED SEQUENCE SPECIFIC DNA BINDING 24 48 1.287e-05 0.0001684
72 INTEGRIN BINDING 42 105 1.451e-05 0.0001872
73 PHOSPHATIDYLINOSITOL BINDING 69 200 1.646e-05 0.0002094
74 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 60 168 1.762e-05 0.0002212
75 ACTIN FILAMENT BINDING 46 121 2.748e-05 0.000337
76 COLLAGEN BINDING 29 65 2.757e-05 0.000337
77 PROTEIN HETERODIMERIZATION ACTIVITY 138 468 3.039e-05 0.0003631
78 RHO GTPASE BINDING 33 78 3.049e-05 0.0003631
79 TRANSITION METAL ION TRANSMEMBRANE TRANSPORTER ACTIVITY 20 39 4.222e-05 0.0004964
80 PROTEIN PHOSPHATASE BINDING 45 120 4.939e-05 0.0005736
81 TRANSCRIPTION COREPRESSOR ACTIVITY 73 221 5.008e-05 0.0005744
82 WNT PROTEIN BINDING 17 31 5.236e-05 0.0005932
83 RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 40 104 6.587e-05 0.0007372
84 PHOSPHOLIPID TRANSLOCATING ATPASE ACTIVITY 11 16 6.836e-05 0.000756
85 PROTEIN COMPLEX SCAFFOLD 29 68 7.603e-05 0.000831
86 PROTEIN TYROSINE PHOSPHATASE ACTIVITY 39 103 0.0001199 0.001295
87 KINASE REGULATOR ACTIVITY 62 186 0.0001331 0.001421
88 MYOSIN V BINDING 11 17 0.0001558 0.001645
89 PHOSPHATASE BINDING 55 162 0.0001817 0.001897
90 STEROID HORMONE RECEPTOR BINDING 32 81 0.0001911 0.001973
91 HISTONE ACETYLTRANSFERASE BINDING 15 28 0.0002054 0.002074
92 PROTEIN PHOSPHATASE 2A BINDING 15 28 0.0002054 0.002074
93 X3 5 CYCLIC AMP PHOSPHODIESTERASE ACTIVITY 10 15 0.0002205 0.002162
94 TRANSCRIPTION COACTIVATOR ACTIVITY 90 296 0.0002211 0.002162
95 PHOSPHATIDYLINOSITOL 4 PHOSPHATE BINDING 12 20 0.0002179 0.002162
96 GTPASE ACTIVITY 77 246 0.0002276 0.002202
97 METAL ION TRANSMEMBRANE TRANSPORTER ACTIVITY 120 417 0.0002892 0.00277
98 RNA POLYMERASE II CORE PROMOTER SEQUENCE SPECIFIC DNA BINDING 23 53 0.0003006 0.00285
99 PHOSPHORIC DIESTER HYDROLASE ACTIVITY 34 90 0.0003339 0.003041
100 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II DISTAL ENHANCER SEQUENCE SPECIFIC BINDING 34 90 0.0003339 0.003041
101 UBIQUITIN LIKE PROTEIN LIGASE ACTIVITY 64 199 0.0003263 0.003041
102 PDZ DOMAIN BINDING 34 90 0.0003339 0.003041
103 GLYCOPROTEIN BINDING 37 101 0.0003798 0.003426
104 I SMAD BINDING 8 11 0.0004089 0.003617
105 SEMAPHORIN RECEPTOR ACTIVITY 8 11 0.0004089 0.003617
106 DIVALENT INORGANIC CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 55 167 0.0004322 0.003788
107 EXTRACELLULAR MATRIX BINDING 22 51 0.0004471 0.003882
108 EPHRIN RECEPTOR BINDING 13 24 0.0004746 0.004083
109 CALMODULIN BINDING 58 179 0.0004896 0.004173
110 PROTEIN SERINE THREONINE TYROSINE KINASE ACTIVITY 18 39 0.0005442 0.004491
111 PHOSPHATIDYLINOSITOL 3 KINASE BINDING 15 30 0.0005463 0.004491
112 RAC GTPASE BINDING 18 39 0.0005442 0.004491
113 TUMOR NECROSIS FACTOR RECEPTOR BINDING 15 30 0.0005463 0.004491
114 HYDROLASE ACTIVITY ACTING ON ESTER BONDS 196 739 0.0006581 0.005363
115 PROTEASE BINDING 37 104 0.0007248 0.005804
116 WNT ACTIVATED RECEPTOR ACTIVITY 12 22 0.0007231 0.005804
117 CYTOKINE RECEPTOR BINDING 81 271 0.0007839 0.006225
118 BHLH TRANSCRIPTION FACTOR BINDING 14 28 0.0008342 0.006529
119 E BOX BINDING 16 34 0.0008431 0.006529
120 PHOSPHATASE REGULATOR ACTIVITY 32 87 0.0008434 0.006529
121 PHOSPHATIDYLINOSITOL PHOSPHATE BINDING 40 116 0.0009182 0.007049
122 LAMIN BINDING 10 17 0.0009289 0.007073
123 RAB GTPASE BINDING 41 120 0.0009818 0.007342
124 MOTOR ACTIVITY 44 131 0.0009798 0.007342
125 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY BINDING 20 47 0.000988 0.007342
126 INOSITOL PHOSPHATE PHOSPHATASE ACTIVITY 11 20 0.001103 0.008136
127 BINDING BRIDGING 55 173 0.001113 0.008141
128 TRANSMEMBRANE TRANSPORTER ACTIVITY 255 997 0.001128 0.008185
129 PROTEIN TYROSINE KINASE BINDING 22 54 0.001137 0.008192
130 S ACYLTRANSFERASE ACTIVITY 14 29 0.001295 0.009182
131 SH2 DOMAIN BINDING 14 29 0.001295 0.009182
132 MANNOSIDASE ACTIVITY 9 15 0.001397 0.009833
NumGOOverlapSizeP ValueAdj. P Value
1 CELL JUNCTION 402 1151 5.061e-27 2.956e-24
2 MEMBRANE REGION 386 1134 1.441e-23 4.209e-21
3 CELL PROJECTION 556 1786 3.361e-23 6.543e-21
4 ANCHORING JUNCTION 196 489 6.181e-21 9.024e-19
5 NEURON PART 405 1265 3.194e-19 3.109e-17
6 GOLGI APPARATUS 452 1445 2.816e-19 3.109e-17
7 NEURON PROJECTION 316 942 2.424e-18 2.022e-16
8 CELL SUBSTRATE JUNCTION 161 398 7.277e-18 5.312e-16
9 CELL LEADING EDGE 145 350 2.764e-17 1.794e-15
10 PLASMA MEMBRANE REGION 308 929 4.316e-17 2.521e-15
11 SYNAPSE 259 754 1.276e-16 6.777e-15
12 MEMBRANE MICRODOMAIN 123 288 4.595e-16 2.236e-14
13 VACUOLE 362 1180 3.347e-14 1.503e-12
14 PERINUCLEAR REGION OF CYTOPLASM 220 642 3.628e-14 1.513e-12
15 CELL PROJECTION PART 301 946 4.167e-14 1.622e-12
16 CYTOSKELETON 555 1967 1.497e-13 5.464e-12
17 AXON 154 418 4.496e-13 1.545e-11
18 ACTIN CYTOSKELETON 161 444 6.09e-13 1.976e-11
19 LAMELLIPODIUM 79 172 8.682e-13 2.669e-11
20 GOLGI APPARATUS PART 280 893 2.215e-12 6.467e-11
21 INTRACELLULAR VESICLE 372 1259 4.505e-12 1.253e-10
22 SOMATODENDRITIC COMPARTMENT 213 650 1.254e-11 3.328e-10
23 ENDOSOME 247 793 9.609e-11 2.44e-09
24 SYNAPSE PART 198 610 1.675e-10 4.075e-09
25 DENDRITE 155 451 1.783e-10 4.165e-09
26 EXCITATORY SYNAPSE 81 197 4.298e-10 9.653e-09
27 ENDOPLASMIC RETICULUM 452 1631 5.817e-10 1.258e-08
28 CELL CELL JUNCTION 134 383 8.21e-10 1.712e-08
29 GOLGI MEMBRANE 219 703 1.125e-09 2.265e-08
30 CYTOPLASMIC REGION 105 287 3.597e-09 7.002e-08
31 POSTSYNAPSE 129 378 9.642e-09 1.816e-07
32 APICAL PART OF CELL 124 361 1.207e-08 2.137e-07
33 RUFFLE 65 156 1.181e-08 2.137e-07
34 CELL PROJECTION MEMBRANE 105 298 3.553e-08 6.103e-07
35 LEADING EDGE MEMBRANE 57 134 3.842e-08 6.411e-07
36 CELL SURFACE 225 757 5.422e-08 8.796e-07
37 CELL CORTEX 87 238 7.963e-08 1.257e-06
38 VACUOLAR PART 207 694 1.391e-07 2.138e-06
39 MICROTUBULE CYTOSKELETON 300 1068 1.479e-07 2.214e-06
40 CYTOSKELETAL PART 388 1436 2.276e-07 3.323e-06
41 KINESIN COMPLEX 29 55 3.902e-07 5.559e-06
42 CELL CORTEX PART 50 119 4.051e-07 5.633e-06
43 FILOPODIUM 42 94 4.613e-07 6.266e-06
44 EARLY ENDOSOME 102 301 4.804e-07 6.376e-06
45 MICROTUBULE 129 405 7.994e-07 1.038e-05
46 VACUOLAR MEMBRANE 176 587 8.275e-07 1.051e-05
47 BASOLATERAL PLASMA MEMBRANE 76 211 9.951e-07 1.236e-05
48 AXON PART 78 219 1.199e-06 1.459e-05
49 VESICLE MEMBRANE 156 512 1.229e-06 1.465e-05
50 APICAL PLASMA MEMBRANE 98 292 1.305e-06 1.524e-05
51 ORGANELLE SUBCOMPARTMENT 103 311 1.421e-06 1.627e-05
52 CELL CELL CONTACT ZONE 31 64 1.754e-06 1.97e-05
53 APICAL JUNCTION COMPLEX 51 128 2.125e-06 2.342e-05
54 PLASMA MEMBRANE RAFT 38 86 2.235e-06 2.417e-05
55 EXTRACELLULAR MATRIX COMPONENT 50 125 2.328e-06 2.472e-05
56 CELL BODY 150 494 2.424e-06 2.528e-05
57 SITE OF POLARIZED GROWTH 57 149 2.566e-06 2.584e-05
58 MIDBODY 52 132 2.532e-06 2.584e-05
59 CORTICAL CYTOSKELETON 36 81 3.47e-06 3.435e-05
60 ENDOPLASMIC RETICULUM PART 314 1163 3.688e-06 3.589e-05
61 SARCOLEMMA 49 125 5.725e-06 5.481e-05
62 CORTICAL ACTIN CYTOSKELETON 28 58 5.97e-06 5.624e-05
63 FILOPODIUM MEMBRANE 13 18 6.116e-06 5.669e-05
64 CYTOPLASMIC VESICLE PART 175 601 6.414e-06 5.852e-05
65 RUFFLE MEMBRANE 35 80 7.271e-06 6.533e-05
66 NUCLEAR ENVELOPE 127 416 1.046e-05 9.208e-05
67 LYTIC VACUOLE 155 526 1.056e-05 9.208e-05
68 MICROTUBULE ASSOCIATED COMPLEX 54 145 1.163e-05 9.992e-05
69 T TUBULE 23 45 1.221e-05 0.0001033
70 CATALYTIC COMPLEX 280 1038 1.345e-05 0.0001122
71 RECEPTOR COMPLEX 103 327 1.673e-05 0.0001376
72 INTRINSIC COMPONENT OF PLASMA MEMBRANE 421 1649 3.584e-05 0.0002907
73 INTERCALATED DISC 24 51 4.626e-05 0.0003701
74 COMPLEX OF COLLAGEN TRIMERS 14 23 5.126e-05 0.0004045
75 ACTIN BASED CELL PROJECTION 62 181 5.471e-05 0.000426
76 TRANS GOLGI NETWORK 65 193 6.571e-05 0.0005049
77 COATED VESICLE 76 234 6.693e-05 0.0005076
78 EXTRACELLULAR MATRIX 125 426 8.886e-05 0.0006653
79 PROTEINACEOUS EXTRACELLULAR MATRIX 107 356 9.975e-05 0.0007374
80 EXTRINSIC COMPONENT OF MEMBRANE 80 252 0.0001039 0.0007585
81 CONTRACTILE FIBER 69 211 0.000112 0.0008072
82 TRANSPORT VESICLE 102 338 0.0001209 0.000861
83 BASEMENT MEMBRANE 36 93 0.0001281 0.0009013
84 NEURON SPINE 44 121 0.0001369 0.0009294
85 ENDOPLASMIC RETICULUM LUMEN 66 201 0.0001362 0.0009294
86 PLASMA MEMBRANE PROTEIN COMPLEX 145 510 0.0001339 0.0009294
87 OUTER MEMBRANE 63 190 0.0001399 0.0009391
88 NEUROMUSCULAR JUNCTION 24 54 0.0001429 0.0009482
89 UBIQUITIN LIGASE COMPLEX 82 262 0.000146 0.0009581
90 ENDOCYTIC VESICLE 80 256 0.0001844 0.001189
91 PRESYNAPSE 87 283 0.0001853 0.001189
92 MAIN AXON 25 58 0.00019 0.001206
93 NUCLEAR MEMBRANE 86 280 0.0002079 0.001306
94 CELL DIVISION SITE 23 52 0.0002134 0.001326
95 ACTOMYOSIN 26 62 0.0002438 0.001499
96 CLATHRIN COATED VESICLE 53 157 0.0002765 0.001682
97 ACTIN FILAMENT 28 70 0.0003689 0.002221
98 TRANSFERASE COMPLEX 189 703 0.0003967 0.002364
99 SEMAPHORIN RECEPTOR COMPLEX 8 11 0.0004089 0.002412
100 COLLAGEN TRIMER 33 88 0.0004735 0.002765
101 I BAND 42 121 0.0005954 0.003442
102 SECRETORY VESICLE 129 461 0.0006123 0.003495
103 LAMELLIPODIUM MEMBRANE 11 19 0.0006164 0.003495
104 GOLGI STACK 43 125 0.0006391 0.003589
105 NUCLEAR OUTER MEMBRANE ENDOPLASMIC RETICULUM MEMBRANE NETWORK 259 1005 0.0006512 0.003622
106 AXOLEMMA 9 14 0.0006912 0.003808
107 PROTEIN KINASE COMPLEX 33 90 0.0007518 0.004103
108 EXOCYTIC VESICLE 47 142 0.0009617 0.0052
109 RECYCLING ENDOSOME 44 131 0.0009798 0.005249
110 COATED PIT 26 67 0.001009 0.00535
111 SPINDLE 85 289 0.001017 0.00535
112 ENDOSOMAL PART 120 430 0.001034 0.005389
113 CUL3 RING UBIQUITIN LIGASE COMPLEX 25 64 0.00112 0.005788
114 PIGMENT GRANULE 36 103 0.001226 0.00628
115 HISTONE DEACETYLASE COMPLEX 24 61 0.001241 0.006301
116 CYTOPLASMIC SIDE OF MEMBRANE 54 170 0.001254 0.006315
117 NUCLEAR CHROMATIN 85 291 0.001274 0.006358
118 PHOSPHATASE COMPLEX 20 48 0.001354 0.0067
119 SPINDLE MICROTUBULE 23 58 0.001372 0.006734
120 MYELIN SHEATH 53 168 0.001639 0.007978
121 EXTRINSIC COMPONENT OF CYTOPLASMIC SIDE OF PLASMA MEMBRANE 34 98 0.001902 0.009105
122 NUCLEAR MATRIX 34 98 0.001902 0.009105
123 PROTEIN COMPLEX INVOLVED IN CELL ADHESION 14 30 0.00195 0.009244
124 LYTIC VACUOLE MEMBRANE 80 275 0.001963 0.009244

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 MAPK_signaling_pathway_hsa04010 119 295 1.843e-13 9.586e-12
2 Focal_adhesion_hsa04510 87 199 1.881e-12 4.891e-11
3 PI3K_Akt_signaling_pathway_hsa04151 129 352 5.348e-11 9.269e-10
4 Wnt_signaling_pathway_hsa04310 65 146 4.534e-10 5.895e-09
5 Hippo_signaling_pathway_hsa04390 67 154 8.182e-10 8.509e-09
6 Cellular_senescence_hsa04218 66 160 1.475e-08 1.278e-07
7 FoxO_signaling_pathway_hsa04068 57 132 2.015e-08 1.497e-07
8 Regulation_of_actin_cytoskeleton_hsa04810 79 208 4.776e-08 3.104e-07
9 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 58 139 6.662e-08 3.849e-07
10 AMPK_signaling_pathway_hsa04152 52 121 1e-07 5.2e-07
11 Rap1_signaling_pathway_hsa04015 77 206 1.52e-07 7.185e-07
12 Ras_signaling_pathway_hsa04014 83 232 4.48e-07 1.941e-06
13 TNF_signaling_pathway_hsa04668 46 108 7.29e-07 2.884e-06
14 p53_signaling_pathway_hsa04115 33 68 7.765e-07 2.884e-06
15 Phosphatidylinositol_signaling_system_hsa04070 43 99 8.749e-07 3.033e-06
16 ErbB_signaling_pathway_hsa04012 38 85 1.573e-06 5.111e-06
17 cGMP_PKG_signaling_pathway_hsa04022 61 163 2.717e-06 8.309e-06
18 TGF_beta_signaling_pathway_hsa04350 36 84 9.554e-06 2.76e-05
19 Sphingolipid_signaling_pathway_hsa04071 46 118 1.293e-05 3.54e-05
20 mTOR_signaling_pathway_hsa04150 55 151 2.04e-05 5.305e-05
21 cAMP_signaling_pathway_hsa04024 68 198 2.232e-05 5.527e-05
22 Adherens_junction_hsa04520 31 72 3.485e-05 8.236e-05
23 HIF_1_signaling_pathway_hsa04066 39 100 5.646e-05 0.0001277
24 Phospholipase_D_signaling_pathway_hsa04072 52 146 6.719e-05 0.0001456
25 Apelin_signaling_pathway_hsa04371 49 137 9.52e-05 0.0001932
26 Endocytosis_hsa04144 78 244 9.773e-05 0.0001932
27 ECM_receptor_interaction_hsa04512 33 82 0.0001003 0.0001932
28 Autophagy_animal_hsa04140 46 128 0.0001348 0.0002503
29 Tight_junction_hsa04530 57 170 0.0002039 0.0003657
30 Ferroptosis_hsa04216 19 40 0.000242 0.0004194
31 Cell_cycle_hsa04110 44 124 0.0002581 0.000433
32 Apoptosis_multiple_species_hsa04215 16 33 0.0005572 0.0009054
33 Apoptosis_hsa04210 45 138 0.001709 0.002694
34 Mitophagy_animal_hsa04137 24 65 0.003369 0.005152
35 NF_kappa_B_signaling_pathway_hsa04064 32 95 0.004278 0.00626
36 Hippo_signaling_pathway_multiple_species_hsa04392 13 29 0.004334 0.00626
37 Gap_junction_hsa04540 30 88 0.004564 0.006414
38 Oocyte_meiosis_hsa04114 38 124 0.01144 0.01565
39 Calcium_signaling_pathway_hsa04020 50 182 0.03475 0.04633
40 VEGF_signaling_pathway_hsa04370 19 59 0.03814 0.04958
41 Hedgehog_signaling_pathway_hsa04340 15 47 0.06547 0.08303
42 Cell_adhesion_molecules_.CAMs._hsa04514 39 145 0.07464 0.09242
43 Cytokine_cytokine_receptor_interaction_hsa04060 65 270 0.176 0.2129
44 Lysosome_hsa04142 31 123 0.1907 0.2204
45 Jak_STAT_signaling_pathway_hsa04630 40 162 0.1907 0.2204
46 Notch_signaling_pathway_hsa04330 12 48 0.3342 0.3778
47 Autophagy_other_hsa04136 8 32 0.3846 0.4255
48 Necroptosis_hsa04217 37 164 0.4097 0.4439
49 Peroxisome_hsa04146 18 83 0.5338 0.5665
50 ABC_transporters_hsa02010 9 45 0.6592 0.6855
51 Phagosome_hsa04145 30 152 0.7398 0.7543
52 Neuroactive_ligand_receptor_interaction_hsa04080 36 278 0.9999 0.9999

lncRNA-mediated sponge

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Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1 RP11-12A2.3 hsa-miR-106b-5p;hsa-miR-146a-5p;hsa-miR-148b-3p;hsa-miR-17-5p;hsa-miR-200b-3p;hsa-miR-20a-5p;hsa-miR-224-5p;hsa-miR-25-3p;hsa-miR-27a-3p;hsa-miR-93-5p 10 SLC1A2 Sponge network -4.779 0 -2.052 1.0E-5 0.338

Quest ID: 608ce144eea29191a183cd62f9107ece