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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-20b-5p AADAC -1.45 0.00948 3.68 0.00236 MirTarget -0.39 0.01619 NA
2 hsa-miR-342-3p AADAC -1.51 0.00036 3.68 0.00236 miRanda -0.71 0.00076 NA
3 hsa-miR-381-3p AADAC -0.14 0.78107 3.68 0.00236 MirTarget -0.37 0.0388 NA
4 hsa-miR-126-5p ABCA12 -1.4 0.0002 5.05 3.0E-5 mirMAP -0.75 0.00166 NA
5 hsa-miR-320c ABCA12 -0.2 0.68946 5.05 3.0E-5 miRanda; miRNATAP -0.4 0.03911 NA
6 hsa-miR-335-5p ABCA12 -0.91 0.05683 5.05 3.0E-5 miRNAWalker2 validate -0.66 0.0005 NA
7 hsa-miR-338-3p ABCA12 0.51 0.34448 5.05 3.0E-5 MirTarget; miRanda -0.52 0.00195 NA
8 hsa-miR-33a-3p ABCA12 -1.71 0.00034 5.05 3.0E-5 mirMAP -0.59 0.00225 NA
9 hsa-miR-361-3p ABCA12 -0.26 0.36923 5.05 3.0E-5 MirTarget -1.21 0.00015 NA
10 hsa-miR-362-3p ABCA12 -1.21 0.01257 5.05 3.0E-5 miRanda; miRNATAP -0.47 0.01341 NA
11 hsa-miR-409-3p ABCA12 -0.55 0.29261 5.05 3.0E-5 PITA -0.36 0.03914 NA
12 hsa-miR-139-5p ABCA13 -1.64 0.00654 2.71 0.0092 miRanda -0.61 0 NA
13 hsa-miR-148b-3p ABCA13 -0.1 0.7723 2.71 0.0092 miRNAWalker2 validate -1.24 0 NA
14 hsa-miR-154-3p ABCA13 -0.64 0.23454 2.71 0.0092 MirTarget -0.39 0.00629 NA
15 hsa-miR-16-1-3p ABCA13 -0.62 0.12369 2.71 0.0092 MirTarget -0.43 0.02886 NA
16 hsa-miR-3065-5p ABCA13 0.74 0.29684 2.71 0.0092 mirMAP -0.36 0.00087 NA
17 hsa-miR-30d-3p ABCA13 -0.36 0.32354 2.71 0.0092 MirTarget -0.49 0.02168 NA
18 hsa-miR-320c ABCA13 -0.2 0.68946 2.71 0.0092 miRanda -0.34 0.03989 NA
19 hsa-miR-324-5p ABCA13 -0.99 0.00957 2.71 0.0092 miRanda -0.92 0 NA
20 hsa-miR-338-3p ABCA13 0.51 0.34448 2.71 0.0092 miRanda -0.28 0.04712 NA
21 hsa-miR-339-5p ABCA13 -0.92 0.04335 2.71 0.0092 miRanda -0.44 0.00934 NA
22 hsa-miR-3613-3p ABCA13 -0.97 0.05661 2.71 0.0092 MirTarget; mirMAP -0.34 0.03058 NA
23 hsa-miR-362-3p ABCA13 -1.21 0.01257 2.71 0.0092 miRanda -0.41 0.0112 NA
24 hsa-miR-362-5p ABCA13 -0.73 0.11206 2.71 0.0092 MirTarget -0.57 0.0007 NA
25 hsa-miR-421 ABCA13 -0.18 0.69194 2.71 0.0092 miRanda -0.42 0.01738 NA
26 hsa-miR-487a-3p ABCA13 0.17 0.76849 2.71 0.0092 MirTarget -0.61 1.0E-5 NA
27 hsa-miR-491-5p ABCA13 -0.79 0.12393 2.71 0.0092 miRanda -0.42 0.00603 NA
28 hsa-miR-496 ABCA13 -0.26 0.66888 2.71 0.0092 miRanda -0.29 0.0197 NA
29 hsa-miR-500a-5p ABCA13 -1.1 0.01791 2.71 0.0092 MirTarget -0.47 0.00419 NA
30 hsa-miR-500b-5p ABCA13 -1.1 0.01787 2.71 0.0092 MirTarget -0.47 0.0042 NA
31 hsa-miR-543 ABCA13 -1.03 0.07135 2.71 0.0092 miRanda -0.44 0.00099 NA
32 hsa-miR-590-3p ABCA13 -0.92 0.03456 2.71 0.0092 miRanda; mirMAP -0.43 0.01579 NA
33 hsa-miR-590-5p ABCA13 -0.98 0.00534 2.71 0.0092 miRanda -0.61 0.00556 NA
34 hsa-miR-628-3p ABCA13 -1.92 0.00404 2.71 0.0092 MirTarget -0.5 1.0E-5 NA
35 hsa-miR-7-1-3p ABCA13 -0.73 0.0834 2.71 0.0092 mirMAP -0.56 0.00242 NA
36 hsa-miR-7-5p ABCA13 0.82 0.51059 2.71 0.0092 MirTarget -0.36 0 NA
37 hsa-miR-192-5p ABCA8 2.1 0.00233 -0.99 0.28561 miRNAWalker2 validate -0.45 0 NA
38 hsa-miR-103a-2-5p ABCD2 -2.06 0.00116 -1.98 0.01409 MirTarget -0.26 0.00558 NA
39 hsa-miR-142-3p ABHD11 -2.4 4.0E-5 0.87 0.03845 miRanda -0.18 0.00067 NA
40 hsa-miR-142-3p ABHD12 -2.4 4.0E-5 0.22 0.40184 miRanda -0.15 0 NA
41 hsa-miR-103a-2-5p ABL2 -2.06 0.00116 -0.13 0.63539 MirTarget -0.13 6.0E-5 NA
42 hsa-miR-141-5p ABL2 2.11 0.00092 -0.13 0.63539 MirTarget; miRNATAP -0.14 1.0E-5 NA
43 hsa-miR-200a-5p ABL2 2.65 1.0E-5 -0.13 0.63539 mirMAP -0.16 0 NA
44 hsa-miR-194-3p ACAD11 2.07 0.00253 -0.57 0.03547 MirTarget -0.11 0.00017 NA
45 hsa-miR-192-5p ACSL1 2.1 0.00233 -0.25 0.53807 miRNAWalker2 validate -0.15 0.00051 NA
46 hsa-miR-320b ACSM5 -0.27 0.55127 -2.35 0.00202 miRanda -0.26 0.03838 NA
47 hsa-miR-142-3p ACTR3B -2.4 4.0E-5 0.29 0.32393 miRanda -0.1 0.00359 NA
48 hsa-miR-141-5p ACVRL1 2.11 0.00092 -0.37 0.23741 MirTarget -0.23 0 NA
49 hsa-miR-194-3p ADAM11 2.07 0.00253 -0.08 0.89144 mirMAP -0.22 0.00035 NA
50 hsa-miR-103a-2-5p ADAM22 -2.06 0.00116 -0.88 0.25527 mirMAP -0.31 0.00069 NA
51 hsa-miR-194-3p ADAMTS15 2.07 0.00253 0.16 0.85349 MirTarget -0.38 2.0E-5 NA
52 hsa-miR-194-5p ADAMTS5 2.55 0.00024 -0.73 0.15695 mirMAP -0.22 3.0E-5 NA
53 hsa-miR-192-5p ADARB1 2.1 0.00233 -0.6 0.08985 mirMAP -0.26 0 NA
54 hsa-miR-141-5p ADCY1 2.11 0.00092 -0.03 0.96543 mirMAP -0.24 0.0093 NA
55 hsa-miR-200a-5p ADD2 2.65 1.0E-5 -1.1 0.14442 mirMAP -0.53 0 NA
56 hsa-miR-3127-5p ADRA1D -0.4 0.31817 -2.38 0.00066 MirTarget -0.52 6.0E-5 NA
57 hsa-miR-192-5p AFAP1 2.1 0.00233 0.11 0.75207 mirMAP -0.1 0.0041 NA
58 hsa-miR-192-5p AFAP1L1 2.1 0.00233 -0.13 0.74099 miRNAWalker2 validate -0.27 0 NA
59 hsa-miR-141-5p AFF2 2.11 0.00092 -0.79 0.24367 mirMAP -0.34 1.0E-5 NA
60 hsa-miR-192-5p AFF2 2.1 0.00233 -0.79 0.24367 mirMAP -0.23 0.00104 NA
61 hsa-miR-194-3p AFF2 2.07 0.00253 -0.79 0.24367 MirTarget -0.17 0.01833 NA
62 hsa-miR-194-5p AFF2 2.55 0.00024 -0.79 0.24367 mirMAP -0.19 0.00694 NA
63 hsa-miR-141-5p AFF3 2.11 0.00092 -0.98 0.22174 mirMAP -0.43 0 NA
64 hsa-miR-200a-5p AFF3 2.65 1.0E-5 -0.98 0.22174 MirTarget -0.44 0 NA
65 hsa-miR-197-3p AGR2 -0.93 0.00091 6.37 0 miRNAWalker2 validate -0.99 0.00474 NA
66 hsa-miR-335-5p AGR2 -0.91 0.05683 6.37 0 miRNAWalker2 validate -0.56 0.00578 NA
67 hsa-miR-342-3p AGR2 -1.51 0.00036 6.37 0 miRanda -1.18 0 NA
68 hsa-miR-361-5p AGR2 -0.3 0.18864 6.37 0 miRanda -2.46 0 NA
69 hsa-miR-543 AGR2 -1.03 0.07135 6.37 0 miRanda -0.81 0 NA
70 hsa-miR-590-3p AGR2 -0.92 0.03456 6.37 0 miRanda -0.71 0.00147 NA
71 hsa-miR-137 AGR3 -0.08 0.93052 4.01 0.00125 miRanda -0.25 0.02171 NA
72 hsa-miR-335-5p AGR3 -0.91 0.05683 4.01 0.00125 miRNAWalker2 validate -0.4 0.03706 NA
73 hsa-miR-543 AGR3 -1.03 0.07135 4.01 0.00125 miRanda -0.69 1.0E-5 NA
74 hsa-miR-590-3p AGR3 -0.92 0.03456 4.01 0.00125 miRanda -0.51 0.01762 NA
75 hsa-miR-142-3p AGXT -2.4 4.0E-5 1.09 0.31324 miRanda -0.31 0.02223 NA
76 hsa-miR-141-5p AIF1L 2.11 0.00092 -1.32 0.02648 MirTarget -0.31 0 NA
77 hsa-miR-330-3p AIM1L 0.23 0.63792 3.48 0.00047 PITA -0.52 0.00079 NA
78 hsa-miR-338-3p AIM1L 0.51 0.34448 3.48 0.00047 miRanda -0.39 0.0047 NA
79 hsa-miR-543 AIM1L -1.03 0.07135 3.48 0.00047 miRanda; miRNATAP -0.73 0 NA
80 hsa-miR-590-5p AIM1L -0.98 0.00534 3.48 0.00047 miRanda; miRNATAP -0.51 0.01609 NA
81 hsa-miR-142-3p AK5 -2.4 4.0E-5 0.41 0.61895 miRanda -0.33 0.00111 NA
82 hsa-miR-200a-5p AKAP2 2.65 1.0E-5 -0.87 0.26357 mirMAP -0.22 0.0164 NA
83 hsa-miR-361-5p AKR1B10 -0.3 0.18864 4.03 0.00721 miRanda -1.67 0.00104 NA
84 hsa-miR-98-5p AKR1B10 -0.22 0.42277 4.03 0.00721 miRNAWalker2 validate -2 0 NA
85 hsa-miR-103a-2-5p AKR1C1 -2.06 0.00116 -0.93 0.17886 mirMAP -0.27 0.00074 NA
86 hsa-miR-1226-3p AKR1C4 -0.64 0.1985 3.77 0.00309 MirTarget -0.42 0.03805 NA
87 hsa-miR-142-3p AKT1S1 -2.4 4.0E-5 0.36 0.14789 MirTarget; miRanda; miRNATAP -0.15 0 NA
88 hsa-miR-192-5p ALCAM 2.1 0.00233 0.09 0.85523 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.12 0.02294 21119604 MicroRNA 192 and 215 are upregulated in human gastric cancer in vivo and suppress ALCAM expression in vitro; Both transfection of mimics of microRNA-192 or -215 and ALCAM knockdown by an ALCAM-specific siRNA significantly increased the migration of HFE145 cells
89 hsa-miR-103a-2-5p ALDH1L2 -2.06 0.00116 0.27 0.69125 mirMAP -0.34 1.0E-5 NA
90 hsa-miR-194-3p ALDH1L2 2.07 0.00253 0.27 0.69125 MirTarget -0.28 8.0E-5 NA
91 hsa-miR-194-5p ALDH1L2 2.55 0.00024 0.27 0.69125 mirMAP -0.31 1.0E-5 NA
92 hsa-miR-129-5p ALDH3A1 1.01 0.36712 3.37 0.0088 MirTarget -0.34 4.0E-5 NA
93 hsa-miR-299-3p ALDH3A1 -1.2 0.03353 3.37 0.0088 miRanda -0.5 0.00358 NA
94 hsa-miR-142-3p AMN1 -2.4 4.0E-5 0.09 0.76433 miRanda -0.15 3.0E-5 NA
95 hsa-miR-192-5p AMOTL1 2.1 0.00233 -0.52 0.23224 mirMAP -0.29 0 NA
96 hsa-miR-141-5p AMZ1 2.11 0.00092 -0.84 0.19343 mirMAP -0.28 0.00012 NA
97 hsa-miR-194-3p AMZ1 2.07 0.00253 -0.84 0.19343 mirMAP -0.28 3.0E-5 NA
98 hsa-miR-144-5p ANG -2.21 0.00517 1.15 0.04302 MirTarget -0.14 0.00945 NA
99 hsa-miR-194-5p ANGPTL1 2.55 0.00024 -0.94 0.28852 MirTarget -0.43 0 NA
100 hsa-miR-194-3p ANGPTL6 2.07 0.00253 -1.69 0.01351 MirTarget -0.29 5.0E-5 NA
101 hsa-miR-192-5p ANKRD6 2.1 0.00233 -0.42 0.28815 miRNAWalker2 validate -0.16 0.00014 NA
102 hsa-miR-542-3p ANKS4B -0.89 0.02064 4.09 9.0E-5 miRanda -0.49 0.01707 NA
103 hsa-miR-766-3p ANKS4B -1.21 0.00153 4.09 9.0E-5 MirTarget -0.42 0.04386 NA
104 hsa-miR-194-3p ANTXR1 2.07 0.00253 -0.08 0.90778 MirTarget -0.23 0.00113 NA
105 hsa-miR-103a-2-5p ANTXR2 -2.06 0.00116 0.45 0.35344 MirTarget -0.18 0.00119 NA
106 hsa-miR-486-5p ANXA13 -1.43 0.04021 3.41 0.00365 miRanda -0.25 0.0464 NA
107 hsa-miR-590-3p ANXA13 -0.92 0.03456 3.41 0.00365 miRanda -0.47 0.02019 NA
108 hsa-miR-93-3p ANXA13 -1.17 0.00228 3.41 0.00365 MirTarget -0.65 0.00424 NA
109 hsa-miR-326 AP1M2 -0.75 0.13947 2.16 2.0E-5 miRNATAP -0.18 0.01699 NA
110 hsa-miR-342-3p AP1M2 -1.51 0.00036 2.16 2.0E-5 miRanda -0.52 0 NA
111 hsa-miR-141-5p AP1S2 2.11 0.00092 -0.98 0.02184 MirTarget -0.36 0 NA
112 hsa-miR-192-5p AP1S2 2.1 0.00233 -0.98 0.02184 miRNAWalker2 validate -0.27 0 NA
113 hsa-miR-215-5p AP1S2 3.07 0.00158 -0.98 0.02184 miRNAWalker2 validate -0.13 8.0E-5 NA
114 hsa-miR-129-5p APOBEC1 1.01 0.36712 4.29 0.00238 MirTarget -0.32 0.00051 NA
115 hsa-miR-137 APOBEC1 -0.08 0.93052 4.29 0.00238 miRanda -0.29 0.01725 NA
116 hsa-miR-139-5p APOBEC1 -1.64 0.00654 4.29 0.00238 miRanda -0.92 0 NA
117 hsa-miR-192-5p APOLD1 2.1 0.00233 0.05 0.92161 miRNAWalker2 validate -0.29 0 NA
118 hsa-miR-194-3p APOLD1 2.07 0.00253 0.05 0.92161 MirTarget -0.25 1.0E-5 NA
119 hsa-miR-215-5p APOLD1 3.07 0.00158 0.05 0.92161 miRNAWalker2 validate -0.18 0 NA
120 hsa-miR-185-3p AQP5 -0.81 0.0588 4.91 0.00121 MirTarget -1.03 9.0E-5 NA
121 hsa-miR-296-3p AQP5 -0.4 0.5034 4.91 0.00121 miRanda -0.64 0.00422 NA
122 hsa-miR-335-5p AQP5 -0.91 0.05683 4.91 0.00121 miRNAWalker2 validate -0.57 0.01636 NA
123 hsa-miR-671-5p AQP6 -0.16 0.729 3.11 0.0022 miRNATAP -0.43 0.00838 NA
124 hsa-miR-200a-5p AR 2.65 1.0E-5 -0.52 0.55352 miRNATAP -0.22 0.03873 24391862 We identified miR-200 b as a downstream target of androgen receptor and linked its expression to decreased tumorigenicity and metastatic capacity of the prostate cancer cells
125 hsa-miR-129-5p AREG 1.01 0.36712 3.07 0.00057 miRanda -0.24 5.0E-5 NA
126 hsa-miR-335-5p AREG -0.91 0.05683 3.07 0.00057 miRNAWalker2 validate -0.44 0.00143 NA
127 hsa-miR-142-3p ARF5 -2.4 4.0E-5 0.16 0.49632 miRanda -0.13 0 NA
128 hsa-miR-141-5p ARHGAP19 2.11 0.00092 -0.39 0.08267 mirMAP -0.12 0 NA
129 hsa-miR-192-5p ARHGAP19 2.1 0.00233 -0.39 0.08267 miRNAWalker2 validate -0.11 1.0E-5 NA
130 hsa-miR-192-5p ARHGAP29 2.1 0.00233 -0.8 0.07773 miRNAWalker2 validate -0.21 1.0E-5 NA
131 hsa-miR-215-5p ARHGAP29 3.07 0.00158 -0.8 0.07773 miRNAWalker2 validate -0.11 0.0008 NA
132 hsa-miR-192-5p ARID5B 2.1 0.00233 -0.68 0.07996 mirMAP -0.23 0 NA
133 hsa-miR-142-3p ARL1 -2.4 4.0E-5 0.29 0.19981 miRanda; miRNATAP -0.14 0 NA
134 hsa-miR-192-5p ARL4C 2.1 0.00233 -0.63 0.25561 miRNAWalker2 validate -0.29 0 NA
135 hsa-miR-215-5p ARL4C 3.07 0.00158 -0.63 0.25561 miRNAWalker2 validate -0.11 0.00667 NA
136 hsa-miR-142-3p ARPC1A -2.4 4.0E-5 0.57 0.03866 miRanda -0.16 0 NA
137 hsa-miR-194-5p ASAP1 2.55 0.00024 -0.35 0.27587 MirTarget; miRNATAP -0.23 0 NA
138 hsa-miR-199a-5p ASPHD1 -0.21 0.63598 2.1 0.00029 miRanda -0.32 0.00118 NA
139 hsa-miR-199b-5p ASPHD1 0.44 0.43893 2.1 0.00029 miRanda -0.17 0.02659 NA
140 hsa-miR-28-5p ASPHD1 -0.53 0.03042 2.1 0.00029 miRanda -0.5 0.00697 NA
141 hsa-miR-142-3p ATG4D -2.4 4.0E-5 0.16 0.62544 miRanda -0.16 3.0E-5 NA
142 hsa-miR-103a-2-5p ATP10B -2.06 0.00116 2.38 0.05795 mirMAP -0.44 0.00317 NA
143 hsa-miR-192-5p ATP10D 2.1 0.00233 -0.5 0.15756 miRNAWalker2 validate -0.14 0.00017 NA
144 hsa-miR-142-3p ATP1B1 -2.4 4.0E-5 1.43 0.00225 PITA; miRanda; miRNATAP -0.18 0.00175 NA
145 hsa-miR-192-5p ATP8B4 2.1 0.00233 -1.37 0.01009 MirTarget -0.29 0 NA
146 hsa-miR-194-5p ATP8B4 2.55 0.00024 -1.37 0.01009 MirTarget -0.28 0 NA
147 hsa-miR-200a-5p ATP8B4 2.65 1.0E-5 -1.37 0.01009 MirTarget -0.34 0 NA
148 hsa-miR-215-5p ATP8B4 3.07 0.00158 -1.37 0.01009 MirTarget -0.11 0.00536 NA
149 hsa-miR-142-3p ATRN -2.4 4.0E-5 -0.04 0.87648 miRanda -0.1 0.00261 NA
150 hsa-miR-142-3p ATXN2 -2.4 4.0E-5 0.19 0.36948 miRanda -0.12 1.0E-5 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 TISSUE DEVELOPMENT 161 1518 1.823e-17 8.482e-14
2 BIOLOGICAL ADHESION 118 1032 3.154e-15 7.337e-12
3 EPITHELIUM DEVELOPMENT 106 945 3.182e-13 4.282e-10
4 REGULATION OF CELL DIFFERENTIATION 146 1492 5.196e-13 4.282e-10
5 CARDIOVASCULAR SYSTEM DEVELOPMENT 93 788 5.521e-13 4.282e-10
6 CIRCULATORY SYSTEM DEVELOPMENT 93 788 5.521e-13 4.282e-10
7 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 134 1395 1.999e-11 1.329e-08
8 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 152 1672 4.904e-11 2.852e-08
9 NEUROGENESIS 132 1402 1.121e-10 5.796e-08
10 TISSUE MORPHOGENESIS 64 533 1.321e-09 4.099e-07
11 ORGAN MORPHOGENESIS 88 841 1.313e-09 4.099e-07
12 VASCULATURE DEVELOPMENT 59 469 1.006e-09 4.099e-07
13 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 110 1142 1.318e-09 4.099e-07
14 POSITIVE REGULATION OF CELL DIFFERENTIATION 87 823 9.924e-10 4.099e-07
15 CELL DEVELOPMENT 130 1426 1.266e-09 4.099e-07
16 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 119 1275 1.742e-09 5.067e-07
17 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 95 957 4.29e-09 1.068e-06
18 CELL MOTILITY 86 835 4.359e-09 1.068e-06
19 LOCALIZATION OF CELL 86 835 4.359e-09 1.068e-06
20 TUBE DEVELOPMENT 64 552 5.342e-09 1.184e-06
21 LOCOMOTION 106 1114 5.245e-09 1.184e-06
22 REGULATION OF CELL PROJECTION ORGANIZATION 64 558 8.154e-09 1.66e-06
23 BLOOD VESSEL MORPHOGENESIS 48 364 8.204e-09 1.66e-06
24 CENTRAL NERVOUS SYSTEM DEVELOPMENT 87 872 1.584e-08 3.072e-06
25 MORPHOGENESIS OF AN EPITHELIUM 50 400 2.367e-08 4.406e-06
26 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 97 1021 2.659e-08 4.758e-06
27 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 77 750 3.334e-08 5.746e-06
28 EPITHELIAL CELL DIFFERENTIATION 57 495 4.71e-08 7.827e-06
29 POSITIVE REGULATION OF NEURON DIFFERENTIATION 41 306 6.419e-08 1.03e-05
30 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 58 513 6.828e-08 1.059e-05
31 REGULATION OF EPITHELIAL CELL PROLIFERATION 39 285 7.597e-08 1.14e-05
32 EPIDERMIS DEVELOPMENT 36 253 8.889e-08 1.293e-05
33 REGULATION OF MICROVILLUS ORGANIZATION 8 14 1.515e-07 2.073e-05
34 REGULATION OF CELL ADHESION 66 629 1.472e-07 2.073e-05
35 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 51 437 1.58e-07 2.1e-05
36 ACTIN FILAMENT BASED PROCESS 52 450 1.639e-07 2.118e-05
37 REGULATION OF NEURON DIFFERENTIATION 60 554 1.851e-07 2.327e-05
38 TUBE MORPHOGENESIS 41 323 2.845e-07 3.484e-05
39 SECRETION 62 588 2.975e-07 3.517e-05
40 HEAD DEVELOPMENT 71 709 3.024e-07 3.517e-05
41 REGULATION OF CELLULAR COMPONENT SIZE 42 337 3.38e-07 3.836e-05
42 REGULATION OF CELL DEVELOPMENT 80 836 3.498e-07 3.875e-05
43 CELL CELL ADHESION 63 608 4.405e-07 4.655e-05
44 ANGIOGENESIS 38 293 4.471e-07 4.655e-05
45 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 90 983 4.502e-07 4.655e-05
46 RESPONSE TO ENDOGENOUS STIMULUS 121 1450 6.592e-07 6.616e-05
47 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 115 1360 6.683e-07 6.616e-05
48 REGULATION OF TRANSPORT 144 1804 6.909e-07 6.697e-05
49 RESPONSE TO WOUNDING 59 563 7.07e-07 6.714e-05
50 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 76 801 9.611e-07 8.944e-05
51 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 43 368 1.423e-06 0.0001298
52 MUSCLE STRUCTURE DEVELOPMENT 48 432 1.517e-06 0.0001357
53 SINGLE ORGANISM CELL ADHESION 50 459 1.645e-06 0.000142
54 REGULATION OF ANATOMICAL STRUCTURE SIZE 51 472 1.648e-06 0.000142
55 CELLULAR COMPONENT MORPHOGENESIS 82 900 1.808e-06 0.0001529
56 PROTEIN LOCALIZATION 142 1805 1.874e-06 0.0001557
57 NEGATIVE REGULATION OF CELL DIFFERENTIATION 61 609 2.068e-06 0.0001688
58 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 31 232 2.685e-06 0.0002154
59 RESPONSE TO XENOBIOTIC STIMULUS 19 105 2.851e-06 0.0002249
60 REGULATION OF CELLULAR COMPONENT MOVEMENT 72 771 3.298e-06 0.0002558
61 GLAND MORPHOGENESIS 18 97 3.565e-06 0.0002703
62 NEURAL PRECURSOR CELL PROLIFERATION 15 70 3.601e-06 0.0002703
63 NEURON DIFFERENTIATION 79 874 3.784e-06 0.0002795
64 REGULATION OF NEURON PROJECTION DEVELOPMENT 45 408 3.896e-06 0.0002833
65 EPITHELIAL CELL PROLIFERATION 17 89 4.39e-06 0.0003142
66 RESPONSE TO HORMONE 80 893 4.589e-06 0.0003235
67 CELL PROLIFERATION 64 672 6.2e-06 0.0004306
68 GLYCOPROTEIN METABOLIC PROCESS 40 353 6.958e-06 0.0004761
69 CELL SUBSTRATE ADHESION 24 164 7.455e-06 0.0005027
70 POSITIVE REGULATION OF CELL DEVELOPMENT 49 472 7.962e-06 0.0005292
71 MULTICELLULAR ORGANISMAL SIGNALING 20 123 8.599e-06 0.0005636
72 FOREBRAIN DEVELOPMENT 40 357 9.118e-06 0.0005892
73 HEART DEVELOPMENT 48 466 1.21e-05 0.000771
74 SKELETAL SYSTEM DEVELOPMENT 47 455 1.382e-05 0.0008242
75 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 64 689 1.372e-05 0.0008242
76 NEURON PROJECTION MORPHOGENESIS 43 402 1.365e-05 0.0008242
77 NEUROBLAST PROLIFERATION 9 29 1.355e-05 0.0008242
78 REGULATION OF CELL PROLIFERATION 118 1496 1.355e-05 0.0008242
79 TELENCEPHALON DEVELOPMENT 29 228 1.463e-05 0.0008615
80 NEGATIVE REGULATION OF CELL COMMUNICATION 98 1192 1.514e-05 0.0008807
81 CONNECTIVE TISSUE DEVELOPMENT 26 194 1.588e-05 0.0009124
82 EMBRYONIC MORPHOGENESIS 53 539 1.614e-05 0.0009157
83 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 17 98 1.679e-05 0.0009411
84 HETEROPHILIC CELL CELL ADHESION VIA PLASMA MEMBRANE CELL ADHESION MOLECULES 11 45 1.912e-05 0.001059
85 REGULATION OF CELLULAR LOCALIZATION 103 1277 2.017e-05 0.001104
86 REGULATION OF DENDRITE DEVELOPMENT 19 120 2.114e-05 0.001144
87 NEURON PROJECTION DEVELOPMENT 53 545 2.19e-05 0.001171
88 NEURON DEVELOPMENT 63 687 2.37e-05 0.001253
89 SKIN DEVELOPMENT 27 211 2.558e-05 0.001337
90 POSITIVE REGULATION OF DENDRITE DEVELOPMENT 13 64 2.922e-05 0.001511
91 RESPONSE TO STEROID HORMONE 49 497 3.12e-05 0.001561
92 CYTOSKELETON ORGANIZATION 73 838 3.076e-05 0.001561
93 UROGENITAL SYSTEM DEVELOPMENT 34 299 3.092e-05 0.001561
94 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 49 498 3.285e-05 0.001626
95 COGNITION 30 251 3.506e-05 0.001717
96 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 70 799 3.737e-05 0.001784
97 RESPONSE TO ORGANIC CYCLIC COMPOUND 78 917 3.738e-05 0.001784
98 ACTION POTENTIAL 16 94 3.758e-05 0.001784
99 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 34 303 4.059e-05 0.001908
100 REGULATION OF VESICLE MEDIATED TRANSPORT 46 462 4.253e-05 0.001979
101 TAXIS 46 464 4.726e-05 0.002135
102 REGULATION OF PHOSPHORUS METABOLIC PROCESS 123 1618 4.724e-05 0.002135
103 LUNG ALVEOLUS DEVELOPMENT 10 41 4.662e-05 0.002135
104 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 13 67 4.86e-05 0.002175
105 SINGLE ORGANISM BEHAVIOR 40 384 4.911e-05 0.002176
106 ION TRANSPORT 100 1262 5.37e-05 0.002352
107 AMINOGLYCAN BIOSYNTHETIC PROCESS 17 107 5.408e-05 0.002352
108 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 125 1656 5.586e-05 0.002407
109 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 13 68 5.717e-05 0.002441
110 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 85 1036 6.084e-05 0.00255
111 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 85 1036 6.084e-05 0.00255
112 REGULATION OF COAGULATION 15 88 6.406e-05 0.002661
113 STEM CELL PROLIFERATION 12 60 6.909e-05 0.002845
114 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 21 154 7.833e-05 0.003197
115 MUSCLE TISSUE DEVELOPMENT 31 275 8.01e-05 0.003222
116 BEHAVIOR 49 516 8.033e-05 0.003222
117 NEGATIVE REGULATION OF LOCOMOTION 30 263 8.363e-05 0.003298
118 SYNAPTIC VESICLE CYCLE 15 90 8.363e-05 0.003298
119 STEM CELL DIFFERENTIATION 24 190 8.672e-05 0.003391
120 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 20 144 8.877e-05 0.003442
121 CELL FATE COMMITMENT 27 227 9.199e-05 0.003509
122 GLAND DEVELOPMENT 40 395 9.141e-05 0.003509
123 NEGATIVE REGULATION OF CELL DEVELOPMENT 33 303 9.38e-05 0.003536
124 CELL PART MORPHOGENESIS 57 633 9.424e-05 0.003536
125 EXTRACELLULAR STRUCTURE ORGANIZATION 33 304 9.994e-05 0.00372
126 POSITIVE REGULATION OF CARTILAGE DEVELOPMENT 8 29 0.0001051 0.003882
127 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 82 1008 0.0001091 0.003966
128 CELL PROJECTION ORGANIZATION 75 902 0.0001089 0.003966
129 NEURON PROJECTION GUIDANCE 25 205 0.0001106 0.003991
130 RESPONSE TO OXYGEN CONTAINING COMPOUND 106 1381 0.0001126 0.003998
131 REGULATION OF TRANSMEMBRANE TRANSPORT 42 426 0.0001124 0.003998
132 REGULATION OF CELL MORPHOGENESIS 51 552 0.0001157 0.004077
133 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 135 1848 0.0001236 0.004261
134 ORGANIC ANION TRANSPORT 39 387 0.0001233 0.004261
135 GLIAL CELL DIFFERENTIATION 19 136 0.0001219 0.004261
136 WOUND HEALING 45 470 0.0001284 0.004392
137 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 17 115 0.0001358 0.004578
138 RESPONSE TO CALCIUM ION 17 115 0.0001358 0.004578
139 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 11 56 0.0001631 0.005461
140 REGULATION OF RECEPTOR ACTIVITY 17 117 0.0001683 0.005554
141 MAMMARY GLAND DEVELOPMENT 17 117 0.0001683 0.005554
142 NEGATIVE REGULATION OF ANOIKIS 6 17 0.0001754 0.005746
143 GLIOGENESIS 22 175 0.0001801 0.005861
144 REGULATION OF BODY FLUID LEVELS 47 506 0.000187 0.00604
145 REGULATION OF HORMONE LEVELS 45 478 0.0001883 0.00604
146 RESPONSE TO LIPID 73 888 0.0001895 0.00604
147 DIGESTIVE TRACT MORPHOGENESIS 10 48 0.0001932 0.006075
148 SECONDARY METABOLIC PROCESS 10 48 0.0001932 0.006075
149 RESPONSE TO CORTICOSTEROID 22 176 0.0001956 0.006109
150 IMMUNE SYSTEM PROCESS 142 1984 0.000206 0.00639
151 REGULATION OF MEMBRANE POTENTIAL 35 343 0.0002119 0.006528
152 EPIDERMAL CELL DIFFERENTIATION 19 142 0.0002166 0.006632
153 PROTEOGLYCAN BIOSYNTHETIC PROCESS 11 58 0.0002261 0.006877
154 REGULATION OF EPITHELIAL CELL MIGRATION 21 166 0.0002292 0.006925
155 NEGATIVE REGULATION OF INTRACELLULAR TRANSPORT 19 143 0.0002375 0.00713
156 PLASMA MEMBRANE ORGANIZATION 24 203 0.0002419 0.007214
157 REGULATION OF CELL PROJECTION SIZE 5 12 0.0002551 0.007533
158 NEGATIVE REGULATION OF CELL PROLIFERATION 56 643 0.0002558 0.007533
159 MEMBRANE ASSEMBLY 7 25 0.0002584 0.007562
160 CELL CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 24 204 0.0002605 0.007575
161 LACTATION 9 41 0.0002649 0.007656
162 SECRETION BY CELL 45 486 0.0002723 0.007728
163 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 18 133 0.0002724 0.007728
164 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 129 1784 0.0002713 0.007728
165 PERIPHERAL NERVOUS SYSTEM DEVELOPMENT 12 69 0.0002789 0.007865
166 SYNAPSE ORGANIZATION 19 145 0.0002846 0.007964
167 RESPONSE TO ALCOHOL 36 362 0.0002858 0.007964
168 POSITIVE REGULATION OF CELL COMMUNICATION 113 1532 0.0003181 0.008619
169 REGULATION OF CELLULAR COMPONENT BIOGENESIS 64 767 0.0003127 0.008619
170 POSITIVE REGULATION OF MOLECULAR FUNCTION 129 1791 0.0003186 0.008619
171 RESPONSE TO GROWTH FACTOR 44 475 0.0003141 0.008619
172 EXOCYTOSIS 32 310 0.0003163 0.008619
173 ENSHEATHMENT OF NEURONS 14 91 0.0003392 0.009072
174 AXON ENSHEATHMENT 14 91 0.0003392 0.009072
175 POSITIVE REGULATION OF CHONDROCYTE DIFFERENTIATION 6 19 0.0003504 0.009317
176 REGULATION OF ACTIN FILAMENT BASED PROCESS 32 312 0.0003545 0.009373
177 ANION TRANSPORT 46 507 0.0003675 0.009553
178 REGULATION OF SYSTEM PROCESS 46 507 0.0003675 0.009553
179 BODY FLUID SECRETION 12 71 0.000367 0.009553
180 EMBRYO DEVELOPMENT 72 894 0.0003803 0.00983
181 MORPHOGENESIS OF AN EPITHELIAL SHEET 9 43 0.0003872 0.009844
182 RESPIRATORY SYSTEM DEVELOPMENT 23 197 0.000387 0.009844
183 REGULATION OF EMBRYONIC DEVELOPMENT 16 114 0.0003865 0.009844
184 ORGANIC ACID TRANSPORT 28 261 0.0003947 0.00998
185 CELL JUNCTION ORGANIZATION 22 185 0.0003975 0.009998
NumGOOverlapSizeP ValueAdj. P Value
1 CYTOSKELETAL PROTEIN BINDING 88 819 3.482e-10 3.235e-07
2 ACTIN BINDING 51 393 4.856e-09 2.256e-06
3 CELL ADHESION MOLECULE BINDING 31 186 1.768e-08 5.474e-06
4 CALCIUM ION BINDING 73 697 3.419e-08 7.94e-06
5 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 67 629 6.694e-08 1.244e-05
6 GROWTH FACTOR BINDING 21 123 2.316e-06 0.0003585
7 PROTEIN DOMAIN SPECIFIC BINDING 61 624 4.521e-06 6e-04
8 MYOSIN V BINDING 7 17 1.526e-05 0.001773
9 MACROMOLECULAR COMPLEX BINDING 111 1399 1.934e-05 0.001996
10 GLYCOPROTEIN BINDING 17 101 2.523e-05 0.002344
11 PROTEIN COMPLEX BINDING 79 935 4.187e-05 0.003536
12 RAB GTPASE BINDING 18 120 7.187e-05 0.005108
13 LIPID BINDING 59 657 7.698e-05 0.005108
14 ALPHA ACTININ BINDING 7 21 7.55e-05 0.005108
15 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 34 315 8.832e-05 0.005128
16 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 27 226 8.532e-05 0.005128
17 PASSIVE TRANSMEMBRANE TRANSPORTER ACTIVITY 45 464 9.545e-05 0.005216
18 REGULATORY REGION NUCLEIC ACID BINDING 69 818 0.0001341 0.005934
19 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 94 1199 0.0001327 0.005934
20 TRANSMEMBRANE TRANSPORTER ACTIVITY 81 997 0.0001253 0.005934
21 GTPASE BINDING 32 295 0.0001282 0.005934
22 INTEGRIN BINDING 16 105 0.0001474 0.006225
23 CATION CHANNEL ACTIVITY 32 298 0.0001547 0.006249
24 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 34 328 0.0001928 0.007465
25 VOLTAGE GATED ION CHANNEL ACTIVITY 23 190 0.0002285 0.008477
26 ACTIN FILAMENT BINDING 17 121 0.0002542 0.008477
27 STEROID HORMONE RECEPTOR ACTIVITY 11 59 0.0002646 0.008477
28 CALMODULIN BINDING 22 179 0.0002495 0.008477
29 MYOSIN BINDING 11 59 0.0002646 0.008477
NumGOOverlapSizeP ValueAdj. P Value
1 CELL PROJECTION 167 1786 4.237e-13 2.474e-10
2 CELL JUNCTION 119 1151 2.747e-12 8.02e-10
3 INTRINSIC COMPONENT OF PLASMA MEMBRANE 148 1649 2.306e-10 3.59e-08
4 CELL PROJECTION PART 98 946 2.459e-10 3.59e-08
5 MEMBRANE REGION 110 1134 8.823e-10 1.031e-07
6 NEURON PART 118 1265 2.124e-09 1.772e-07
7 NEURON PROJECTION 95 942 1.917e-09 1.772e-07
8 PLASMA MEMBRANE REGION 93 929 4.155e-09 3.033e-07
9 CELL SURFACE 77 757 4.929e-08 3.009e-06
10 CELL LEADING EDGE 45 350 5.152e-08 3.009e-06
11 SYNAPSE 75 754 1.82e-07 9.665e-06
12 ANCHORING JUNCTION 54 489 4.124e-07 2.007e-05
13 SOMATODENDRITIC COMPARTMENT 65 650 1.013e-06 4.549e-05
14 ACTIN CYTOSKELETON 49 444 1.437e-06 5.596e-05
15 ACTIN BASED CELL PROJECTION 27 181 1.406e-06 5.596e-05
16 CELL PROJECTION MEMBRANE 37 298 1.829e-06 6.676e-05
17 INTRACELLULAR VESICLE 106 1259 2.308e-06 7.929e-05
18 CELL CELL JUNCTION 43 383 4.042e-06 0.0001311
19 ENDOPLASMIC RETICULUM 129 1631 4.505e-06 0.0001385
20 FILOPODIUM 17 94 9.467e-06 0.0002633
21 BASOLATERAL PLASMA MEMBRANE 28 211 9.189e-06 0.0002633
22 GOLGI APPARATUS PART 78 893 1.498e-05 0.0003976
23 LAMELLIPODIUM 24 172 1.692e-05 0.0004296
24 DENDRITE 46 451 2.342e-05 0.0005699
25 APICAL PART OF CELL 39 361 2.709e-05 0.0006328
26 CATION CHANNEL COMPLEX 23 167 3.11e-05 0.0006726
27 GOLGI APPARATUS 113 1445 3.03e-05 0.0006726
28 SYNAPSE PART 57 610 3.411e-05 0.0007114
29 APICAL PLASMA MEMBRANE 33 292 4.547e-05 0.0009157
30 PLASMA MEMBRANE PROTEIN COMPLEX 49 510 6.008e-05 0.00117
31 VESICLE MEMBRANE 49 512 6.624e-05 0.001248
32 SECRETORY VESICLE 45 461 8.204e-05 0.001497
33 LEADING EDGE MEMBRANE 19 134 9.973e-05 0.001765
34 CELL SUBSTRATE JUNCTION 40 398 0.0001076 0.001849
35 BASEMENT MEMBRANE 15 93 0.0001227 0.001998
36 EXTRACELLULAR MATRIX COMPONENT 18 125 0.0001231 0.001998
37 SECRETORY GRANULE 36 352 0.0001656 0.002614
38 SECRETORY GRANULE MEMBRANE 13 78 0.0002445 0.003757
39 RUFFLE 20 156 0.0002676 0.004007
40 CYTOPLASMIC VESICLE PART 53 601 0.0002745 0.004007
41 RUFFLE MEMBRANE 13 80 0.0003164 0.004507
42 MICROVILLUS MEMBRANE 6 19 0.0003504 0.004872
43 PLATELET ALPHA GRANULE MEMBRANE 5 13 0.0003963 0.005184
44 SITE OF POLARIZED GROWTH 19 149 0.0004036 0.005184
45 CYTOSKELETON 139 1967 0.0004172 0.005184
46 MEMBRANE MICRODOMAIN 30 288 0.0004121 0.005184
47 CELL BODY 45 494 0.0003887 0.005184
48 VOLTAGE GATED SODIUM CHANNEL COMPLEX 5 14 0.0005893 0.00717
49 EXOCYTIC VESICLE 18 142 0.0006091 0.00726

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Cell_adhesion_molecules_.CAMs._hsa04514 20 145 9.787e-05 0.005089
2 Hippo_signaling_pathway_hsa04390 20 154 0.0002248 0.005846
3 Regulation_of_actin_cytoskeleton_hsa04810 24 208 0.0003482 0.006036
4 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 18 139 0.0004703 0.006114
5 Apelin_signaling_pathway_hsa04371 17 137 0.001085 0.01129
6 Wnt_signaling_pathway_hsa04310 17 146 0.002181 0.0189
7 PI3K_Akt_signaling_pathway_hsa04151 32 352 0.002623 0.01949
8 mTOR_signaling_pathway_hsa04150 17 151 0.003114 0.02024
9 Calcium_signaling_pathway_hsa04020 19 182 0.004301 0.02146
10 ECM_receptor_interaction_hsa04512 11 82 0.004312 0.02146
11 Tight_junction_hsa04530 18 170 0.004627 0.02146
12 MAPK_signaling_pathway_hsa04010 27 295 0.004953 0.02146
13 Ras_signaling_pathway_hsa04014 22 232 0.007051 0.02821
14 Focal_adhesion_hsa04510 19 199 0.01094 0.04062
15 AMPK_signaling_pathway_hsa04152 13 121 0.01314 0.04554
16 ErbB_signaling_pathway_hsa04012 9 85 0.03844 0.1187
17 Hedgehog_signaling_pathway_hsa04340 6 47 0.03881 0.1187
18 Rap1_signaling_pathway_hsa04015 17 206 0.05224 0.1509
19 cGMP_PKG_signaling_pathway_hsa04022 14 163 0.05612 0.1536
20 Ferroptosis_hsa04216 5 40 0.06149 0.1599
21 Hippo_signaling_pathway_multiple_species_hsa04392 4 29 0.06756 0.1673
22 Adherens_junction_hsa04520 7 72 0.09109 0.2153
23 p53_signaling_pathway_hsa04115 6 68 0.1574 0.3169
24 Peroxisome_hsa04146 7 83 0.1576 0.3169
25 Phospholipase_D_signaling_pathway_hsa04072 11 146 0.1621 0.3169
26 Jak_STAT_signaling_pathway_hsa04630 12 162 0.1622 0.3169
27 TGF_beta_signaling_pathway_hsa04350 7 84 0.1645 0.3169
28 ABC_transporters_hsa02010 4 45 0.2211 0.4106
29 NF_kappa_B_signaling_pathway_hsa04064 7 95 0.2487 0.4444
30 Notch_signaling_pathway_hsa04330 4 48 0.2564 0.4444
31 HIF_1_signaling_pathway_hsa04066 7 100 0.2906 0.4875
32 Phagosome_hsa04145 10 152 0.3003 0.488
33 Endocytosis_hsa04144 15 244 0.3322 0.5116
34 Gap_junction_hsa04540 6 88 0.3345 0.5116
35 Autophagy_animal_hsa04140 8 128 0.3818 0.5654
36 VEGF_signaling_pathway_hsa04370 4 59 0.3915 0.5654
37 FoxO_signaling_pathway_hsa04068 8 132 0.4148 0.583
38 Phosphatidylinositol_signaling_system_hsa04070 6 99 0.441 0.6034
39 Mitophagy_animal_hsa04137 4 65 0.4644 0.6192
40 Cellular_senescence_hsa04218 9 160 0.492 0.636
41 Oocyte_meiosis_hsa04114 7 124 0.5014 0.636
42 Apoptosis_multiple_species_hsa04215 2 33 0.5354 0.6629
43 Cytokine_cytokine_receptor_interaction_hsa04060 14 270 0.5926 0.7167
44 cAMP_signaling_pathway_hsa04024 9 198 0.7421 0.8771
45 Sphingolipid_signaling_pathway_hsa04071 5 118 0.7659 0.8851
46 TNF_signaling_pathway_hsa04668 4 108 0.8383 0.9274
47 Apoptosis_hsa04210 5 138 0.8692 0.9417
48 Necroptosis_hsa04217 5 164 0.9437 0.9935
49 Lysosome_hsa04142 3 123 0.9642 0.9935
50 Cell_cycle_hsa04110 2 124 0.9916 0.9935
51 Neuroactive_ligand_receptor_interaction_hsa04080 7 278 0.9935 0.9935

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1

UCA1

 hsa-miR-129-5p;hsa-miR-130b-5p;hsa-miR-132-3p;hsa-miR-148b-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20b-5p;hsa-miR-26a-5p;hsa-miR-29b-2-5p;hsa-miR-3065-5p;hsa-miR-362-5p;hsa-miR-432-5p;hsa-miR-495-3p;hsa-miR-539-5p;hsa-miR-590-3p;hsa-miR-7-1-3p 16 GPRC5A Sponge network 1.481 0.28957 3.955 0.00162 0.622
2

UCA1

 hsa-miR-101-5p;hsa-miR-103a-2-5p;hsa-miR-125a-5p;hsa-miR-126-5p;hsa-miR-129-5p;hsa-miR-154-5p;hsa-miR-186-5p;hsa-miR-339-5p;hsa-miR-501-5p;hsa-miR-539-5p;hsa-miR-590-3p;hsa-miR-590-5p 12 TMPRSS4 Sponge network 1.481 0.28957 5.411 0.00024 0.619
3

DIO3OS

 hsa-miR-103a-2-5p;hsa-miR-125a-5p;hsa-miR-129-5p;hsa-miR-154-5p;hsa-miR-186-5p;hsa-miR-330-5p;hsa-miR-3613-3p;hsa-miR-501-5p;hsa-miR-539-5p;hsa-miR-769-5p 10 TMPRSS4 Sponge network 1.18 0.0997 5.411 0.00024 0.584
4

DIO3OS

 hsa-let-7g-3p;hsa-miR-129-5p;hsa-miR-130b-5p;hsa-miR-132-3p;hsa-miR-148b-3p;hsa-miR-148b-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20b-5p;hsa-miR-29b-2-5p;hsa-miR-301a-3p;hsa-miR-30b-3p;hsa-miR-30c-1-3p;hsa-miR-330-3p;hsa-miR-3607-3p;hsa-miR-532-3p;hsa-miR-539-5p;hsa-miR-589-3p;hsa-miR-93-3p 19 GPRC5A Sponge network 1.18 0.0997 3.955 0.00162 0.573
5

UCA1

 hsa-miR-126-5p;hsa-miR-129-5p;hsa-miR-135a-5p;hsa-miR-299-3p;hsa-miR-374a-5p;hsa-miR-374b-5p;hsa-miR-539-5p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-628-3p 11 EREG Sponge network 1.481 0.28957 4.411 0.00138 0.56
6

PVT1

 hsa-let-7g-3p;hsa-miR-129-5p;hsa-miR-130b-5p;hsa-miR-132-3p;hsa-miR-148b-3p;hsa-miR-148b-5p;hsa-miR-29b-2-5p;hsa-miR-301a-3p;hsa-miR-330-3p;hsa-miR-432-5p;hsa-miR-532-3p;hsa-miR-592 12 GPRC5A Sponge network 0.67 0.32654 3.955 0.00162 0.522
7

EGOT

 hsa-let-7g-3p;hsa-miR-137;hsa-miR-148b-3p;hsa-miR-148b-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-29b-2-5p;hsa-miR-301a-3p;hsa-miR-495-3p;hsa-miR-592;hsa-miR-7-1-3p 11 GPRC5A Sponge network -1.196 0.1622 3.955 0.00162 0.451
8

UCA1

 hsa-miR-154-3p;hsa-miR-16-1-3p;hsa-miR-3065-5p;hsa-miR-339-5p;hsa-miR-362-5p;hsa-miR-487a-3p;hsa-miR-500a-5p;hsa-miR-500b-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-628-3p;hsa-miR-7-1-3p 12 ABCA13 Sponge network 1.481 0.28957 2.713 0.0092 0.403
9

PVT1

 hsa-miR-1224-5p;hsa-miR-130b-5p;hsa-miR-136-5p;hsa-miR-148a-5p;hsa-miR-148b-3p;hsa-miR-204-5p;hsa-miR-216a-5p;hsa-miR-324-3p;hsa-miR-501-5p;hsa-miR-628-5p;hsa-miR-758-3p 11 DNAH3 Sponge network 0.67 0.32654 3.099 0.00111 0.387
10

EGOT

 hsa-miR-139-5p;hsa-miR-148b-3p;hsa-miR-154-3p;hsa-miR-16-1-3p;hsa-miR-320c;hsa-miR-324-5p;hsa-miR-421;hsa-miR-487a-3p;hsa-miR-491-5p;hsa-miR-7-1-3p 10 ABCA13 Sponge network -1.196 0.1622 2.713 0.0092 0.378
11 H19 hsa-let-7g-3p;hsa-miR-129-5p;hsa-miR-132-3p;hsa-miR-148b-3p;hsa-miR-148b-5p;hsa-miR-29b-2-5p;hsa-miR-301a-3p;hsa-miR-30b-3p;hsa-miR-454-3p;hsa-miR-495-3p;hsa-miR-532-3p;hsa-miR-539-5p;hsa-miR-589-3p;hsa-miR-592 14 GPRC5A Sponge network -0.02 0.98077 3.955 0.00162 0.366
12 HCP5 hsa-miR-129-5p;hsa-miR-132-3p;hsa-miR-148b-3p;hsa-miR-148b-5p;hsa-miR-29b-2-5p;hsa-miR-301a-3p;hsa-miR-30b-3p;hsa-miR-330-3p;hsa-miR-495-3p;hsa-miR-539-5p 10 GPRC5A Sponge network -0.577 0.20814 3.955 0.00162 0.361
13

DIO3OS

 hsa-miR-1224-5p;hsa-miR-130b-5p;hsa-miR-136-5p;hsa-miR-148a-5p;hsa-miR-148b-3p;hsa-miR-188-5p;hsa-miR-204-5p;hsa-miR-324-3p;hsa-miR-377-5p;hsa-miR-501-5p;hsa-miR-539-5p;hsa-miR-628-5p;hsa-miR-98-5p 13 DNAH3 Sponge network 1.18 0.0997 3.099 0.00111 0.361
14

NEAT1

 hsa-miR-1270;hsa-miR-132-5p;hsa-miR-148b-3p;hsa-miR-185-3p;hsa-miR-204-5p;hsa-miR-324-3p;hsa-miR-326;hsa-miR-382-5p;hsa-miR-421;hsa-miR-431-5p;hsa-miR-532-3p;hsa-miR-543;hsa-miR-628-5p;hsa-miR-744-3p 14 ONECUT3 Sponge network -0.3 0.62793 3.758 0.00762 0.36
15 AGAP11 hsa-miR-107;hsa-miR-141-3p;hsa-miR-147b;hsa-miR-148b-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-200a-3p;hsa-miR-30b-3p;hsa-miR-455-3p;hsa-miR-455-5p 10 WDFY4 Sponge network -0.834 0.15213 -2.494 0.0049 0.342
16

DIO3OS

 hsa-miR-106a-5p;hsa-miR-1270;hsa-miR-130b-5p;hsa-miR-132-5p;hsa-miR-148a-3p;hsa-miR-148b-3p;hsa-miR-148b-5p;hsa-miR-185-3p;hsa-miR-204-5p;hsa-miR-20b-5p;hsa-miR-296-5p;hsa-miR-324-3p;hsa-miR-382-5p;hsa-miR-455-3p;hsa-miR-532-3p;hsa-miR-628-5p;hsa-miR-769-3p;hsa-miR-93-3p;hsa-miR-98-5p 19 ONECUT3 Sponge network 1.18 0.0997 3.758 0.00762 0.342
17 CASC2 hsa-miR-126-5p;hsa-miR-130a-3p;hsa-miR-142-5p;hsa-miR-146a-5p;hsa-miR-146b-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-224-3p;hsa-miR-2355-3p;hsa-miR-24-2-5p;hsa-miR-26a-2-3p;hsa-miR-30a-3p 12 RAB3B Sponge network 0.854 0.028 2.286 0.00176 0.331
18

PVT1

 hsa-miR-130b-5p;hsa-miR-132-5p;hsa-miR-148a-3p;hsa-miR-148b-3p;hsa-miR-148b-5p;hsa-miR-204-5p;hsa-miR-324-3p;hsa-miR-382-5p;hsa-miR-431-5p;hsa-miR-532-3p;hsa-miR-543;hsa-miR-628-5p;hsa-miR-769-3p 13 ONECUT3 Sponge network 0.67 0.32654 3.758 0.00762 0.302
19

KCNQ1OT1

 hsa-miR-126-5p;hsa-miR-154-5p;hsa-miR-186-5p;hsa-miR-330-5p;hsa-miR-369-3p;hsa-miR-376a-5p;hsa-miR-485-3p;hsa-miR-496;hsa-miR-539-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-769-5p 12 TMPRSS4 Sponge network 0.495 0.30013 5.411 0.00024 0.299
20

UCA1

 hsa-miR-1224-5p;hsa-miR-130b-5p;hsa-miR-136-5p;hsa-miR-148a-5p;hsa-miR-204-5p;hsa-miR-324-3p;hsa-miR-377-5p;hsa-miR-495-3p;hsa-miR-501-5p;hsa-miR-539-5p;hsa-miR-7-1-3p 11 DNAH3 Sponge network 1.481 0.28957 3.099 0.00111 0.29
21

UCA1

 hsa-miR-130b-5p;hsa-miR-132-5p;hsa-miR-148b-5p;hsa-miR-204-5p;hsa-miR-20b-5p;hsa-miR-296-5p;hsa-miR-324-3p;hsa-miR-382-5p;hsa-miR-590-3p;hsa-miR-744-3p 10 ONECUT3 Sponge network 1.481 0.28957 3.758 0.00762 0.274
22

UCA1

 hsa-miR-101-5p;hsa-miR-126-5p;hsa-miR-186-5p;hsa-miR-204-5p;hsa-miR-3065-5p;hsa-miR-323a-3p;hsa-miR-340-5p;hsa-miR-374a-5p;hsa-miR-374b-5p;hsa-miR-409-3p;hsa-miR-495-3p;hsa-miR-7-1-3p 12 SLC7A11 Sponge network 1.481 0.28957 2.313 0.00139 0.265

Quest ID: f7def754296cac29b1b4481087d5b8eb