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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-139-5p AAK1 -2.11 0 0.62 0 PITA -0.14 0 NA
2 hsa-miR-10b-5p ABAT 2.87 0 -2.16 0 mirMAP -0.16 9.0E-5 NA
3 hsa-miR-183-5p ABAT 2.33 0 -2.16 0 MirTarget -0.27 0 NA
4 hsa-miR-183-5p ABCA8 2.33 0 -2.96 0 MirTarget -0.39 0 NA
5 hsa-miR-424-5p ABCB9 -2.63 0 1.01 0 mirMAP -0.11 0.00796 NA
6 hsa-miR-139-5p ABCC5 -2.11 0 1.23 0 miRanda; mirMAP -0.25 0 NA
7 hsa-miR-3607-3p ABCC5 -2.16 0 1.23 0 MirTarget; miRNATAP -0.15 0 NA
8 hsa-miR-424-5p ABCC5 -2.63 0 1.23 0 MirTarget; miRNATAP -0.13 0 NA
9 hsa-miR-10b-3p ABHD2 2.77 0 -1.2 0 mirMAP -0.13 0 NA
10 hsa-miR-10b-5p ABHD2 2.87 0 -1.2 0 mirMAP -0.11 1.0E-5 NA
11 hsa-miR-224-5p ABHD2 2.67 0 -1.2 0 mirMAP -0.12 0 NA
12 hsa-miR-139-5p ABI2 -2.11 0 0.14 0.17339 miRanda -0.15 0 NA
13 hsa-miR-139-5p ABL2 -2.11 0 0.6 0 miRanda -0.12 0 NA
14 hsa-miR-139-5p ACACA -2.11 0 0.78 0 miRanda -0.21 0 NA
15 hsa-miR-224-5p ACAT1 2.67 0 -1.62 0 MirTarget -0.13 0 NA
16 hsa-miR-139-5p ACD -2.11 0 0.57 0 miRanda -0.18 0 NA
17 hsa-miR-139-5p ACLY -2.11 0 1.02 0 miRanda -0.23 0 NA
18 hsa-miR-144-3p ACSL4 -2.98 0 2.07 0 MirTarget; miRNATAP -0.33 0 NA
19 hsa-miR-424-5p ACSL4 -2.63 0 2.07 0 MirTarget; miRNATAP -0.22 0.01698 NA
20 hsa-miR-139-3p ADAM11 -2.53 0 1.25 0 MirTarget -0.22 0.0001 NA
21 hsa-miR-3607-3p ADAM11 -2.16 0 1.25 0 miRNATAP -0.25 0 NA
22 hsa-miR-139-5p ADAM12 -2.11 0 0.93 0.0022 miRanda -0.37 0 NA
23 hsa-miR-3607-3p ADAM12 -2.16 0 0.93 0.0022 mirMAP; miRNATAP -0.27 3.0E-5 NA
24 hsa-miR-144-3p ADAM22 -2.98 0 1.17 0.00038 mirMAP -0.21 0.00016 NA
25 hsa-miR-3607-3p ADAM22 -2.16 0 1.17 0.00038 mirMAP -0.3 2.0E-5 NA
26 hsa-miR-183-5p ADAMTS13 2.33 0 -3.25 0 mirMAP -0.14 0 NA
27 hsa-miR-10b-3p ADAMTS2 2.77 0 -2.31 0 mirMAP -0.4 0 24897960 The addition of miR-10b RERs to the Nottingham Prognostic Index NPI provided an improvement in discrimination power and risk reclassification abilities for the clinical outcomes at 36 months
28 hsa-miR-10b-5p ADAMTS2 2.87 0 -2.31 0 MirTarget -0.3 0 24897960 The addition of miR-10b RERs to the Nottingham Prognostic Index NPI provided an improvement in discrimination power and risk reclassification abilities for the clinical outcomes at 36 months
29 hsa-miR-224-5p ADAMTS2 2.67 0 -2.31 0 mirMAP -0.2 4.0E-5 NA
30 hsa-miR-139-5p ADAMTS6 -2.11 0 0.7 0.00475 miRanda -0.28 0 NA
31 hsa-miR-139-5p ADAMTS9 -2.11 0 0.8 0 miRanda -0.21 0 NA
32 hsa-miR-10b-3p ADCY1 2.77 0 -2.7 0 mirMAP -0.23 0.00031 NA
33 hsa-miR-10b-5p ADCY1 2.87 0 -2.7 0 mirMAP -0.13 0.03244 NA
34 hsa-miR-224-5p ADCYAP1 2.67 0 -1.14 0.00042 mirMAP -0.11 0.02928 NA
35 hsa-miR-139-5p ADORA2B -2.11 0 -0.06 0.82124 miRanda -0.28 0 NA
36 hsa-miR-10b-5p ADRA1B 2.87 0 -2.34 0 miRNAWalker2 validate -0.18 6.0E-5 NA
37 hsa-miR-3607-3p AFAP1 -2.16 0 0.33 0.05949 mirMAP -0.15 7.0E-5 NA
38 hsa-miR-33b-5p AFF2 -2.29 0 1.4 0.00046 mirMAP; miRNATAP -0.33 3.0E-5 NA
39 hsa-miR-3607-3p AFF2 -2.16 0 1.4 0.00046 mirMAP -0.29 0.00066 NA
40 hsa-miR-3607-3p AFF3 -2.16 0 -0.32 0.28974 mirMAP; miRNATAP -0.17 0.0084 NA
41 hsa-miR-424-5p AGAP3 -2.63 0 0.26 0.00332 miRNATAP -0.1 0 NA
42 hsa-miR-3607-3p AGPAT4 -2.16 0 0.87 7.0E-5 mirMAP -0.16 0.00056 NA
43 hsa-miR-144-3p AGRN -2.98 0 0.72 0 miRNATAP -0.15 0 NA
44 hsa-miR-139-5p AHSA2 -2.11 0 1.41 0 miRanda -0.16 0 NA
45 hsa-miR-183-5p AKAP12 2.33 0 -1.36 0 miRNAWalker2 validate; miRTarBase -0.11 0.00212 NA
46 hsa-miR-675-3p AKR1C1 -2.78 0 -0.12 0.65413 mirMAP -0.14 4.0E-5 NA
47 hsa-miR-224-5p ALDH6A1 2.67 0 -2.57 0 mirMAP -0.24 0 NA
48 hsa-miR-139-5p ALG11 -2.11 0 0.55 8.0E-5 miRanda -0.18 0 NA
49 hsa-miR-139-5p ALOX5 -2.11 0 -0.64 0.02074 miRanda -0.14 0.03743 NA
50 hsa-miR-10b-3p AMOT 2.77 0 -0.9 0.00079 mirMAP -0.14 0.00214 NA
51 hsa-miR-139-5p AMPD3 -2.11 0 0.13 0.47274 miRanda -0.21 0 NA
52 hsa-miR-224-5p AMZ1 2.67 0 -1.28 0.00014 mirMAP -0.11 0.03925 NA
53 hsa-miR-139-5p ANAPC7 -2.11 0 0.84 0 miRanda -0.2 0 NA
54 hsa-miR-3607-3p ANGPT2 -2.16 0 1.15 0 mirMAP -0.1 0.01062 NA
55 hsa-miR-424-5p ANKRD13B -2.63 0 1.57 0 miRNATAP -0.16 0.00097 NA
56 hsa-miR-139-5p ANKRD13D -2.11 0 0.79 0 miRanda -0.26 0 NA
57 hsa-miR-139-5p ANKRD27 -2.11 0 0.9 0 miRanda -0.24 0 NA
58 hsa-miR-33b-5p ANKRD29 -2.29 0 1.13 4.0E-5 MirTarget -0.11 0.03891 NA
59 hsa-miR-424-5p ANKRD29 -2.63 0 1.13 4.0E-5 MirTarget -0.28 5.0E-5 NA
60 hsa-miR-199a-3p ANKRD52 -2.33 0 1.46 0 PITA; miRNATAP -0.11 0 NA
61 hsa-miR-199b-3p ANKRD52 -2.33 0 1.46 0 PITA; miRNATAP -0.11 0 NA
62 hsa-miR-3607-3p ANKRD52 -2.16 0 1.46 0 miRNATAP -0.22 0 NA
63 hsa-miR-139-5p ANKS1B -2.11 0 1.43 0.00012 miRanda -0.38 2.0E-5 NA
64 hsa-miR-424-5p ANLN -2.63 0 3.89 0 miRNAWalker2 validate; miRTarBase -0.59 0 NA
65 hsa-miR-3607-3p ANO4 -2.16 0 1.36 0 MirTarget; miRNATAP -0.28 1.0E-5 NA
66 hsa-miR-10b-3p ANTXR1 2.77 0 -0.48 0.04009 mirMAP -0.18 0 NA
67 hsa-miR-139-5p AP3B1 -2.11 0 0.63 0 miRanda -0.12 0 NA
68 hsa-miR-199a-3p AP3B1 -2.33 0 0.63 0 PITA -0.1 0 NA
69 hsa-miR-199b-3p AP3B1 -2.33 0 0.63 0 PITA -0.1 0 NA
70 hsa-miR-106b-5p APC 0.65 0 -0.18 0.06792 miRNAWalker2 validate; miRTarBase -0.15 0.00024 23087084 miR 106b downregulates adenomatous polyposis coli and promotes cell proliferation in human hepatocellular carcinoma; Moreover we demonstrated that miR-106b downregulates APC expression by directly targeting the 3'-untranslated region of APC messenger RNA; Taken together our results suggest that miR-106b plays an important role in promoting the proliferation of human hepatoma cells and presents a novel mechanism of micro RNA-mediated direct suppression of APC expression in cancer cells
71 hsa-miR-21-5p APC 1.51 0 -0.18 0.06792 miRNAWalker2 validate -0.17 0 23773491; 24832083 The prognostic significance of APC gene mutation and miR 21 expression in advanced stage colorectal cancer; The aim of this study was to analyse the association of APC gene mutation and miR-21 expression with clinical outcome in CRC patients; APC gene mutation and expression of APC and miR-21 were analysed by direct DNA sequencing and real-time reverse transcription polymerase chain reaction; APC gene expression was low in CRC and negatively correlated with miR-21 expression and gene mutation; In Taiwan downregulation of the APC gene in CRC correlated with gene mutation and miR-21 upregulation; APC mutation and miR-21 expression could be used to predict the clinical outcome of CRC especially in patients with advanced disease;MicroRNA 21 promotes tumour malignancy via increased nuclear translocation of β catenin and predicts poor outcome in APC mutated but not in APC wild type colorectal cancer; However in our preliminary data the prognostic value of miR-21 levels was observed only in adenomatous polyposis coli APC-mutated tumours not in APC-wild-type tumours; We enrolled 165 colorectal tumour to determine APC mutation miR-21 levels and nuclear β-catenin expression by direct sequencing real-time PCR and immunohistochemistry
72 hsa-let-7a-5p APC2 -0.33 0.00046 1.72 0 TargetScan -0.3 0.00538 NA
73 hsa-miR-125a-5p APC2 -0.91 0 1.72 0 mirMAP -0.2 0.0003 NA
74 hsa-miR-125b-5p APC2 -1.36 0 1.72 0 mirMAP -0.16 0.01164 NA
75 hsa-miR-185-3p APC2 -0.27 0.0854 1.72 0 MirTarget -0.13 0.04272 NA
76 hsa-miR-194-3p APC2 -0.77 3.0E-5 1.72 0 mirMAP -0.17 0.00111 NA
77 hsa-miR-199a-5p APC2 -1.99 0 1.72 0 mirMAP -0.1 0.00178 NA
78 hsa-miR-20a-3p APC2 -0.32 0.04679 1.72 0 mirMAP -0.25 7.0E-5 NA
79 hsa-miR-2355-5p APC2 -0.23 0.15791 1.72 0 mirMAP -0.14 0.01613 NA
80 hsa-miR-23b-5p APC2 -1.05 0 1.72 0 mirMAP -0.22 0.0013 NA
81 hsa-miR-28-5p APC2 -0.43 0 1.72 0 mirMAP -0.3 0.00527 NA
82 hsa-miR-340-3p APC2 -0.33 0.0033 1.72 0 mirMAP -0.22 0.01183 NA
83 hsa-miR-505-5p APC2 -0.77 1.0E-5 1.72 0 mirMAP -0.15 0.00924 NA
84 hsa-miR-424-5p APLN -2.63 0 3.69 0 MirTarget; miRNATAP -0.75 0 NA
85 hsa-miR-10b-5p APLNR 2.87 0 -0.98 9.0E-5 miRNAWalker2 validate -0.18 1.0E-5 NA
86 hsa-miR-139-5p APOBEC3D -2.11 0 -0.1 0.63988 miRanda -0.16 0.00156 NA
87 hsa-miR-424-5p ARFGAP1 -2.63 0 0.64 0 mirMAP -0.15 0 NA
88 hsa-miR-139-5p ARHGAP18 -2.11 0 0.24 0.06197 miRanda -0.11 0.00018 NA
89 hsa-miR-3607-3p ARHGEF3 -2.16 0 0.51 0.00381 MirTarget; miRNATAP -0.12 0.00127 NA
90 hsa-miR-139-5p ARID3B -2.11 0 0.46 0.00021 miRanda -0.16 0 NA
91 hsa-miR-139-5p ARL6IP6 -2.11 0 0.35 0.00326 miRanda -0.15 0 NA
92 hsa-miR-139-5p ARMC2 -2.11 0 0.75 0 MirTarget -0.11 0.00085 NA
93 hsa-miR-10b-3p ARNT2 2.77 0 -0.54 0.16571 mirMAP -0.2 0.00226 NA
94 hsa-miR-3607-3p ARNT2 -2.16 0 -0.54 0.16571 mirMAP -0.17 0.04206 NA
95 hsa-miR-139-5p ARPC4 -2.11 0 0.19 0.01193 miRanda -0.12 0 NA
96 hsa-miR-3607-3p ASAP1 -2.16 0 0.6 1.0E-5 MirTarget; mirMAP; miRNATAP -0.1 0.00049 NA
97 hsa-miR-33b-5p ATP10A -2.29 0 0.42 0.12977 mirMAP -0.15 0.00626 NA
98 hsa-miR-3607-3p ATP10B -2.16 0 -0.24 0.56639 MirTarget -0.24 0.00744 NA
99 hsa-miR-139-5p ATP1B1 -2.11 0 0.44 0.00298 miRanda -0.12 0.00038 NA
100 hsa-miR-144-3p ATP1B1 -2.98 0 0.44 0.00298 miRNATAP -0.13 0 NA
101 hsa-miR-139-5p ATP1B3 -2.11 0 0.87 0 miRanda -0.27 0 NA
102 hsa-miR-139-3p ATP5G2 -2.53 0 0.3 0.00093 miRNATAP -0.13 0 NA
103 hsa-miR-139-5p ATP5G2 -2.11 0 0.3 0.00093 miRanda -0.13 0 NA
104 hsa-miR-139-5p ATP7A -2.11 0 0.25 0.01885 MirTarget; PITA; miRanda -0.1 4.0E-5 NA
105 hsa-miR-424-5p ATXN7L2 -2.63 0 1.07 0 MirTarget; miRNATAP -0.23 0 NA
106 hsa-miR-424-5p ATXN7L3 -2.63 0 0.7 0 MirTarget; miRNATAP -0.14 0 NA
107 hsa-miR-320a AXIN1 0.33 0.02214 0.3 0.00968 miRNAWalker2 validate -0.1 0.00946 NA
108 hsa-let-7b-3p AXIN2 -1.22 0 0.11 0.75298 miRNATAP -0.27 0.0205 NA
109 hsa-let-7g-3p AXIN2 -1.14 0 0.11 0.75298 MirTarget -0.33 0.01126 NA
110 hsa-miR-15b-5p AXIN2 0.23 0.08248 0.11 0.75298 miRTarBase; MirTarget; miRNATAP -0.45 0.00081 NA
111 hsa-miR-16-2-3p AXIN2 -0.03 0.80516 0.11 0.75298 mirMAP -0.64 0 NA
112 hsa-miR-16-5p AXIN2 -0.4 0.0001 0.11 0.75298 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.49 0.00421 NA
113 hsa-miR-195-3p AXIN2 -1.09 0 0.11 0.75298 mirMAP -0.31 0.00083 NA
114 hsa-miR-195-5p AXIN2 -1.86 0 0.11 0.75298 MirTarget; miRNATAP -0.25 0.00506 NA
115 hsa-miR-26b-3p AXIN2 -1.26 0 0.11 0.75298 MirTarget -0.59 3.0E-5 NA
116 hsa-miR-326 AXIN2 -1.88 0 0.11 0.75298 miRanda -0.36 2.0E-5 NA
117 hsa-miR-338-5p AXIN2 -0.22 0.25239 0.11 0.75298 miRNATAP -0.34 0.00017 NA
118 hsa-miR-424-5p AXIN2 -2.63 0 0.11 0.75298 MirTarget; miRNATAP -0.19 0.03018 NA
119 hsa-miR-497-5p AXIN2 -1.41 0 0.11 0.75298 MirTarget; miRNATAP -0.29 0.00329 NA
120 hsa-miR-616-3p AXIN2 -0.7 2.0E-5 0.11 0.75298 MirTarget -0.42 8.0E-5 NA
121 hsa-miR-139-5p B3GALNT2 -2.11 0 0.86 0 MirTarget; miRanda -0.14 0 NA
122 hsa-miR-3607-3p B3GNT5 -2.16 0 0.79 0.0009 MirTarget; miRNATAP -0.13 0.01377 NA
123 hsa-miR-10b-5p B3GNT7 2.87 0 -1.25 0 mirMAP -0.12 0.00321 NA
124 hsa-miR-10b-5p BACH2 2.87 0 -1.99 0 MirTarget; miRNATAP -0.17 2.0E-5 NA
125 hsa-miR-139-5p BAGE -2.11 0 1.25 0.00088 miRanda -0.41 0 NA
126 hsa-miR-139-5p BAZ2A -2.11 0 0.46 0 miRanda; miRNATAP -0.15 0 NA
127 hsa-miR-139-5p BBC3 -2.11 0 0.8 0 miRNATAP -0.23 0 NA
128 hsa-miR-144-3p BBC3 -2.98 0 0.8 0 miRNATAP -0.11 0 NA
129 hsa-miR-139-5p BBS7 -2.11 0 0.27 0.09013 miRanda -0.11 0.00434 NA
130 hsa-miR-3607-3p BCL11A -2.16 0 -0.12 0.7089 mirMAP; miRNATAP -0.25 0.00018 NA
131 hsa-miR-183-5p BCL6 2.33 0 -0.38 0.00305 miRNATAP -0.1 0 NA
132 hsa-miR-144-3p BCL9 -2.98 0 1.18 0 miRNATAP -0.21 0 NA
133 hsa-miR-139-5p BCORL1 -2.11 0 0.51 0.00032 miRanda -0.19 0 NA
134 hsa-miR-144-3p BEND3 -2.98 0 1.02 0 miRNATAP -0.15 0 NA
135 hsa-miR-3607-3p BEND3 -2.16 0 1.02 0 mirMAP; miRNATAP -0.21 0 NA
136 hsa-miR-139-5p BFSP1 -2.11 0 1.36 0 miRanda -0.36 0 NA
137 hsa-miR-1269a BHLHE22 3.58 0 -1.88 0 MirTarget -0.18 0 NA
138 hsa-miR-139-5p BICD1 -2.11 0 0.8 0.0004 miRanda -0.27 0 NA
139 hsa-miR-1269a BMPER 3.58 0 -6.23 0 MirTarget -0.2 0 NA
140 hsa-miR-33b-5p BRIP1 -2.29 0 1.06 5.0E-5 MirTarget -0.18 0.00038 NA
141 hsa-miR-424-5p BRPF3 -2.63 0 0.35 0.00299 miRNATAP -0.12 1.0E-5 NA
142 hsa-miR-33b-5p BSN -2.29 0 0.94 2.0E-5 mirMAP -0.11 0.01425 NA
143 hsa-miR-3607-3p BSN -2.16 0 0.94 2.0E-5 miRNATAP -0.11 0.01794 NA
144 hsa-miR-139-5p BTBD3 -2.11 0 0.3 0.00861 PITA; miRanda; miRNATAP -0.11 4.0E-5 NA
145 hsa-miR-139-5p BTG3 -2.11 0 0.62 0 MirTarget; PITA; miRanda; miRNATAP -0.15 0 NA
146 hsa-miR-15b-5p BTRC 0.23 0.08248 -0 0.97671 MirTarget; miRNATAP -0.12 0 NA
147 hsa-miR-16-5p BTRC -0.4 0.0001 -0 0.97671 miRNAWalker2 validate; MirTarget; miRNATAP -0.17 0 NA
148 hsa-miR-193a-3p BTRC -0.12 0.30939 -0 0.97671 MirTarget; miRanda -0.15 0 NA
149 hsa-miR-193b-3p BTRC -0.17 0.27202 -0 0.97671 miRNAWalker2 validate -0.16 0 NA
150 hsa-miR-361-3p BTRC 0.28 0.00549 -0 0.97671 MirTarget; PITA; miRNATAP -0.1 0.00495 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 WNT SIGNALING PATHWAY 100 351 7.781e-41 3.621e-37
2 CANONICAL WNT SIGNALING PATHWAY 43 95 1.821e-27 4.237e-24
3 REGULATION OF WNT SIGNALING PATHWAY 76 310 1.46e-26 2.264e-23
4 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 216 1805 1.077e-23 1.253e-20
5 EMBRYONIC MORPHOGENESIS 97 539 1.209e-22 1.125e-19
6 EMBRYO DEVELOPMENT 131 894 9.472e-22 5.509e-19
7 NEUROGENESIS 177 1402 8.013e-22 5.509e-19
8 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 209 1784 9.424e-22 5.509e-19
9 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 53 197 7.326e-21 3.788e-18
10 POSITIVE REGULATION OF GENE EXPRESSION 202 1733 9.641e-21 4.486e-18
11 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 58 236 1.332e-20 5.635e-18
12 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 138 1004 2.65e-20 1.028e-17
13 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 136 1021 8.262e-19 2.957e-16
14 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 177 1517 3.45e-18 1.146e-15
15 TUBE MORPHOGENESIS 65 323 4.672e-18 1.449e-15
16 REGULATION OF CELL CYCLE 127 949 9.101e-18 2.647e-15
17 CELL PROLIFERATION 101 672 1.056e-17 2.729e-15
18 NEGATIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 44 162 1.025e-17 2.729e-15
19 TISSUE MORPHOGENESIS 87 533 1.289e-17 3.156e-15
20 REGULATION OF CELL DIFFERENTIATION 173 1492 1.648e-17 3.834e-15
21 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 88 554 4.747e-17 9.535e-15
22 NON CANONICAL WNT SIGNALING PATHWAY 40 140 4.527e-17 9.535e-15
23 MORPHOGENESIS OF AN EPITHELIUM 72 400 4.413e-17 9.535e-15
24 CELL CYCLE 157 1316 4.918e-17 9.535e-15
25 MITOTIC CELL CYCLE 108 766 7.974e-17 1.484e-14
26 NEGATIVE REGULATION OF GENE EXPRESSION 171 1493 8.648e-17 1.548e-14
27 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 185 1672 1.296e-16 2.233e-14
28 TISSUE DEVELOPMENT 172 1518 1.957e-16 3.253e-14
29 CELL CYCLE PROCESS 135 1081 2.587e-16 4.15e-14
30 TUBE DEVELOPMENT 86 552 3.615e-16 5.607e-14
31 BETA CATENIN DESTRUCTION COMPLEX DISASSEMBLY 16 22 1.488e-15 2.233e-13
32 REGULATION OF CELL CYCLE PROCESS 85 558 2.09e-15 3.039e-13
33 REGULATION OF EMBRYONIC DEVELOPMENT 34 114 2.459e-15 3.467e-13
34 NEURON DIFFERENTIATION 114 874 3.21e-15 4.393e-13
35 POSITIVE REGULATION OF MOLECULAR FUNCTION 189 1791 6.666e-15 8.862e-13
36 ORGAN MORPHOGENESIS 110 841 8.441e-15 1.091e-12
37 APPENDAGE DEVELOPMENT 41 169 9.564e-15 1.171e-12
38 LIMB DEVELOPMENT 41 169 9.564e-15 1.171e-12
39 EPITHELIUM DEVELOPMENT 119 945 9.973e-15 1.19e-12
40 CELL DEVELOPMENT 159 1426 1.323e-14 1.539e-12
41 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 100 740 1.925e-14 2.185e-12
42 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 94 684 4.413e-14 4.889e-12
43 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 118 957 5.828e-14 6.306e-12
44 REGULATION OF CELL PROLIFERATION 162 1496 9.099e-14 9.622e-12
45 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 151 1360 9.576e-14 9.901e-12
46 REGULATION OF PHOSPHORUS METABOLIC PROCESS 170 1618 2.881e-13 2.914e-11
47 POSITIVE REGULATION OF CATALYTIC ACTIVITY 162 1518 3.139e-13 3.107e-11
48 GASTRULATION 37 155 3.288e-13 3.122e-11
49 REGULATION OF PROTEIN MODIFICATION PROCESS 177 1710 3.25e-13 3.122e-11
50 REGULATION OF CELL DEVELOPMENT 105 836 4.95e-13 4.606e-11
51 NEGATIVE REGULATION OF CELL COMMUNICATION 135 1192 5.377e-13 4.906e-11
52 PATTERN SPECIFICATION PROCESS 66 418 5.854e-13 5.238e-11
53 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 159 1492 6.061e-13 5.321e-11
54 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 97 750 7.13e-13 6.144e-11
55 REGULATION OF ORGAN MORPHOGENESIS 47 242 7.905e-13 6.687e-11
56 EMBRYONIC ORGAN MORPHOGENESIS 51 279 9.699e-13 8.059e-11
57 REGULATION OF ORGANELLE ORGANIZATION 133 1178 1.024e-12 8.357e-11
58 REGULATION OF CELL CYCLE PHASE TRANSITION 55 321 1.895e-12 1.52e-10
59 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 33 134 2.469e-12 1.947e-10
60 REGULATION OF GROWTH 85 633 2.732e-12 2.119e-10
61 CENTRAL NERVOUS SYSTEM DEVELOPMENT 106 872 2.992e-12 2.282e-10
62 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 41 199 3.152e-12 2.366e-10
63 SKELETAL SYSTEM DEVELOPMENT 68 455 3.575e-12 2.64e-10
64 CHROMOSOME ORGANIZATION 117 1009 4.816e-12 3.502e-10
65 INTRACELLULAR SIGNAL TRANSDUCTION 162 1572 5.563e-12 3.982e-10
66 SENSORY ORGAN DEVELOPMENT 71 493 7.06e-12 4.977e-10
67 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 55 337 1.376e-11 9.553e-10
68 REGIONALIZATION 52 311 1.974e-11 1.351e-09
69 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 126 1142 2.068e-11 1.395e-09
70 POSITIVE REGULATION OF CELL CYCLE 54 332 2.415e-11 1.605e-09
71 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 166 1656 2.734e-11 1.792e-09
72 HEAD DEVELOPMENT 89 709 3.365e-11 2.175e-09
73 PROTEIN PHOSPHORYLATION 109 944 3.552e-11 2.264e-09
74 REGULATION OF MITOTIC CELL CYCLE 67 468 3.65e-11 2.295e-09
75 MAMMARY GLAND DEVELOPMENT 29 117 4.407e-11 2.734e-09
76 CELLULAR COMPONENT MORPHOGENESIS 105 900 4.55e-11 2.775e-09
77 REGULATION OF CELL DEATH 151 1472 4.592e-11 2.775e-09
78 RESPONSE TO OXYGEN LEVELS 51 311 6.396e-11 3.815e-09
79 POSITIVE REGULATION OF CELL DEATH 79 605 6.662e-11 3.924e-09
80 POSITIVE REGULATION OF CELL DIFFERENTIATION 98 823 6.747e-11 3.924e-09
81 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 96 801 7.472e-11 4.292e-09
82 REGULATION OF CELL MORPHOGENESIS 74 552 8.022e-11 4.552e-09
83 CELL CYCLE CHECKPOINT 38 194 9.466e-11 5.306e-09
84 EMBRYONIC ORGAN DEVELOPMENT 60 406 1.08e-10 5.984e-09
85 TUBE FORMATION 30 129 1.13e-10 6.184e-09
86 NEGATIVE REGULATION OF CELL CYCLE PROCESS 40 214 1.362e-10 7.371e-09
87 MITOTIC CELL CYCLE CHECKPOINT 31 139 1.721e-10 9.207e-09
88 REGULATION OF CELL GROWTH 58 391 1.911e-10 1.01e-08
89 NEGATIVE REGULATION OF CELL CYCLE 62 433 1.974e-10 1.032e-08
90 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 88 724 2.343e-10 1.211e-08
91 REGULATION OF NEURON DIFFERENTIATION 73 554 2.386e-10 1.22e-08
92 POSITIVE REGULATION OF CELL COMMUNICATION 153 1532 2.423e-10 1.226e-08
93 REGULATION OF ESTABLISHMENT OF PLANAR POLARITY 27 110 2.604e-10 1.303e-08
94 WNT SIGNALING PATHWAY CALCIUM MODULATING PATHWAY 16 39 2.825e-10 1.398e-08
95 ANTERIOR POSTERIOR PATTERN SPECIFICATION 37 194 3.69e-10 1.807e-08
96 POSITIVE REGULATION OF WNT SIGNALING PATHWAY 32 152 4.223e-10 2.047e-08
97 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 31 146 6.322e-10 3.033e-08
98 PALATE DEVELOPMENT 23 85 6.882e-10 3.267e-08
99 REGULATION OF BINDING 46 283 7.438e-10 3.496e-08
100 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 31 147 7.556e-10 3.516e-08
101 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 68 513 7.747e-10 3.569e-08
102 CELL DIVISION 63 460 8.858e-10 4.041e-08
103 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 120 1135 9.255e-10 4.181e-08
104 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 184 1977 9.444e-10 4.225e-08
105 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 112 1036 9.855e-10 4.326e-08
106 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 112 1036 9.855e-10 4.326e-08
107 POSITIVE REGULATION OF CELL CYCLE PROCESS 42 247 1.004e-09 4.364e-08
108 REGULATION OF PROTEIN LOCALIZATION 105 950 1.013e-09 4.364e-08
109 REGULATION OF CELLULAR LOCALIZATION 131 1277 1.032e-09 4.407e-08
110 NEURAL TUBE DEVELOPMENT 31 149 1.073e-09 4.471e-08
111 NEURAL TUBE FORMATION 24 94 1.076e-09 4.471e-08
112 REGULATION OF TRANSPORT 171 1804 1.064e-09 4.471e-08
113 REGULATION OF CELLULAR PROTEIN LOCALIZATION 71 552 1.224e-09 5.041e-08
114 NEGATIVE REGULATION OF CELL DIFFERENTIATION 76 609 1.264e-09 5.158e-08
115 MUSCLE STRUCTURE DEVELOPMENT 60 432 1.298e-09 5.253e-08
116 FORMATION OF PRIMARY GERM LAYER 26 110 1.341e-09 5.379e-08
117 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 92 799 1.52e-09 5.992e-08
118 UROGENITAL SYSTEM DEVELOPMENT 47 299 1.511e-09 5.992e-08
119 REGULATION OF TRANSFERASE ACTIVITY 104 946 1.642e-09 6.42e-08
120 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 130 1275 1.769e-09 6.859e-08
121 REGULATION OF CELL PROJECTION ORGANIZATION 71 558 1.955e-09 7.519e-08
122 EAR MORPHOGENESIS 26 112 2.029e-09 7.739e-08
123 CHROMATIN ORGANIZATION 80 663 2.23e-09 8.434e-08
124 REGULATION OF STEM CELL DIFFERENTIATION 26 113 2.486e-09 9.33e-08
125 CHROMATIN MODIFICATION 69 539 2.571e-09 9.569e-08
126 REGULATION OF NEURON PROJECTION DEVELOPMENT 57 408 2.707e-09 9.997e-08
127 REPRODUCTION 131 1297 2.756e-09 1.006e-07
128 NEGATIVE REGULATION OF ORGANELLE ORGANIZATION 55 387 2.766e-09 1.006e-07
129 RESPONSE TO OXYGEN CONTAINING COMPOUND 137 1381 3.657e-09 1.319e-07
130 PHOSPHORYLATION 125 1228 4.147e-09 1.484e-07
131 MAMMARY GLAND EPITHELIUM DEVELOPMENT 17 53 6.793e-09 2.413e-07
132 NEGATIVE REGULATION OF CELL GROWTH 32 170 7.875e-09 2.776e-07
133 POSITIVE REGULATION OF CELL PROLIFERATION 91 814 8.084e-09 2.828e-07
134 NEGATIVE REGULATION OF GROWTH 39 236 9.032e-09 3.136e-07
135 SEGMENTATION 22 89 1.015e-08 3.497e-07
136 POSITIVE REGULATION OF RESPONSE TO STIMULUS 176 1929 1.028e-08 3.517e-07
137 EMBRYONIC DIGIT MORPHOGENESIS 18 61 1.091e-08 3.705e-07
138 SENSORY ORGAN MORPHOGENESIS 39 239 1.296e-08 4.369e-07
139 REGULATION OF DEVELOPMENTAL GROWTH 44 289 1.351e-08 4.524e-07
140 CARDIOVASCULAR SYSTEM DEVELOPMENT 88 788 1.514e-08 4.997e-07
141 CIRCULATORY SYSTEM DEVELOPMENT 88 788 1.514e-08 4.997e-07
142 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 117 1152 1.544e-08 5.06e-07
143 REGULATION OF ESTABLISHMENT OF PLANAR POLARITY INVOLVED IN NEURAL TUBE CLOSURE 9 14 1.567e-08 5.064e-07
144 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 27 131 1.561e-08 5.064e-07
145 REGULATION OF CATABOLIC PROCESS 83 731 1.878e-08 6.025e-07
146 INNER EAR MORPHOGENESIS 22 92 1.956e-08 6.232e-07
147 EMBRYONIC SKELETAL SYSTEM MORPHOGENESIS 22 93 2.417e-08 7.651e-07
148 REGULATION OF EXTENT OF CELL GROWTH 23 101 2.523e-08 7.933e-07
149 REGULATION OF CYTOSKELETON ORGANIZATION 63 502 2.722e-08 8.454e-07
150 MAMMARY GLAND DUCT MORPHOGENESIS 12 28 2.725e-08 8.454e-07
151 CELLULAR RESPONSE TO OXYGEN LEVELS 28 143 2.761e-08 8.508e-07
152 OSTEOBLAST DIFFERENTIATION 26 126 2.797e-08 8.563e-07
153 CELL FATE COMMITMENT 37 227 3.135e-08 9.534e-07
154 RHYTHMIC PROCESS 44 298 3.427e-08 1.035e-06
155 REGULATION OF HYDROLASE ACTIVITY 129 1327 3.646e-08 1.095e-06
156 GLAND DEVELOPMENT 53 395 3.883e-08 1.158e-06
157 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 134 1395 3.944e-08 1.169e-06
158 MAMMARY GLAND MORPHOGENESIS 14 40 4.158e-08 1.224e-06
159 MESODERM MORPHOGENESIS 18 66 4.268e-08 1.249e-06
160 SKELETAL SYSTEM MORPHOGENESIS 34 201 4.433e-08 1.289e-06
161 REPRODUCTIVE SYSTEM DEVELOPMENT 54 408 4.609e-08 1.332e-06
162 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 50 365 4.844e-08 1.391e-06
163 NEGATIVE REGULATION OF CELL DIVISION 17 60 5.443e-08 1.554e-06
164 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 25 122 5.95e-08 1.688e-06
165 FOREBRAIN DEVELOPMENT 49 357 6.192e-08 1.746e-06
166 REGULATION OF KINASE ACTIVITY 85 776 6.41e-08 1.797e-06
167 CELLULAR RESPONSE TO LIPID 58 457 6.563e-08 1.807e-06
168 DORSAL VENTRAL AXIS SPECIFICATION 10 20 6.539e-08 1.807e-06
169 BRANCHING INVOLVED IN MAMMARY GLAND DUCT MORPHOGENESIS 10 20 6.539e-08 1.807e-06
170 EAR DEVELOPMENT 33 195 6.895e-08 1.887e-06
171 CELL PROJECTION ORGANIZATION 95 902 7.01e-08 1.908e-06
172 DIGESTIVE TRACT MORPHOGENESIS 15 48 7.786e-08 2.106e-06
173 POSITIVE REGULATION OF HYDROLASE ACTIVITY 95 905 8.203e-08 2.204e-06
174 REGULATION OF PROTEIN CATABOLIC PROCESS 52 393 8.243e-08 2.204e-06
175 CELLULAR RESPONSE TO STRESS 145 1565 9.81e-08 2.608e-06
176 LOCOMOTION 111 1114 1.01e-07 2.671e-06
177 RESPONSE TO ABIOTIC STIMULUS 104 1024 1.029e-07 2.695e-06
178 REGULATION OF CHROMOSOME ORGANIZATION 41 278 1.031e-07 2.695e-06
179 REGULATION OF DNA REPLICATION 29 161 1.067e-07 2.774e-06
180 PROTEIN COMPLEX SUBUNIT ORGANIZATION 142 1527 1.086e-07 2.809e-06
181 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 71 616 1.144e-07 2.941e-06
182 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 29 162 1.226e-07 3.134e-06
183 NEGATIVE REGULATION OF CELL PROLIFERATION 73 643 1.384e-07 3.519e-06
184 POSITIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 24 119 1.494e-07 3.777e-06
185 OSSIFICATION 38 251 1.51e-07 3.798e-06
186 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 100 983 1.698e-07 4.247e-06
187 POSITIVE REGULATION OF PROTEIN CATABOLIC PROCESS 39 263 1.815e-07 4.516e-06
188 REGULATION OF CATENIN IMPORT INTO NUCLEUS 11 27 1.964e-07 4.861e-06
189 CONNECTIVE TISSUE DEVELOPMENT 32 194 1.992e-07 4.904e-06
190 RESPONSE TO ENDOGENOUS STIMULUS 135 1450 2.167e-07 5.306e-06
191 REGULATION OF DNA METABOLIC PROCESS 46 340 2.39e-07 5.823e-06
192 MORPHOGENESIS OF A BRANCHING STRUCTURE 29 167 2.407e-07 5.833e-06
193 IMMUNE SYSTEM DEVELOPMENT 67 582 2.731e-07 6.583e-06
194 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 107 1087 3.176e-07 7.617e-06
195 CELL PART MORPHOGENESIS 71 633 3.271e-07 7.805e-06
196 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 34 218 3.306e-07 7.848e-06
197 NEGATIVE REGULATION OF MITOTIC NUCLEAR DIVISION 12 34 3.502e-07 8.271e-06
198 PROTEIN COMPLEX BIOGENESIS 110 1132 4.083e-07 9.546e-06
199 PROTEIN COMPLEX ASSEMBLY 110 1132 4.083e-07 9.546e-06
200 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 23 117 4.372e-07 1.017e-05
201 NEURON DEVELOPMENT 75 687 4.429e-07 1.025e-05
202 RESPONSE TO LIPID 91 888 4.537e-07 1.042e-05
203 POSITIVE REGULATION OF CELL DEVELOPMENT 57 472 4.546e-07 1.042e-05
204 REGULATION OF CELL SIZE 29 172 4.581e-07 1.045e-05
205 REGULATION OF GASTRULATION 12 35 5.037e-07 1.134e-05
206 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 69 616 5.044e-07 1.134e-05
207 BIOLOGICAL ADHESION 102 1032 5.034e-07 1.134e-05
208 REGULATION OF DNA BINDING 20 93 5.452e-07 1.22e-05
209 MITOTIC NUCLEAR DIVISION 47 361 5.515e-07 1.225e-05
210 POSITIVE REGULATION OF CELL CYCLE ARREST 19 85 5.544e-07 1.225e-05
211 REGULATION OF PROTEIN PHOSPHATASE TYPE 2A ACTIVITY 10 24 5.556e-07 1.225e-05
212 SOMITE DEVELOPMENT 18 78 6.639e-07 1.457e-05
213 CARTILAGE DEVELOPMENT 26 147 6.913e-07 1.507e-05
214 REGULATION OF MUSCLE ADAPTATION 16 63 6.93e-07 1.507e-05
215 SISTER CHROMATID SEGREGATION 29 176 7.506e-07 1.624e-05
216 BETA CATENIN TCF COMPLEX ASSEMBLY 13 43 8.811e-07 1.898e-05
217 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 161 1848 9.123e-07 1.956e-05
218 NEGATIVE REGULATION OF CHROMOSOME ORGANIZATION 20 96 9.319e-07 1.989e-05
219 NEURON PROJECTION MORPHOGENESIS 50 402 9.649e-07 2.05e-05
220 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 99 1008 9.938e-07 2.102e-05
221 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 34 229 1.063e-06 2.238e-05
222 RESPONSE TO HORMONE 90 893 1.074e-06 2.25e-05
223 NEURON PROJECTION DEVELOPMENT 62 545 1.139e-06 2.377e-05
224 CELLULAR RESPONSE TO KETONE 17 73 1.178e-06 2.447e-05
225 FAT CELL DIFFERENTIATION 21 106 1.201e-06 2.484e-05
226 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 33 220 1.207e-06 2.485e-05
227 CELLULAR RESPONSE TO ALCOHOL 22 115 1.256e-06 2.574e-05
228 NEGATIVE REGULATION OF CELL DEATH 88 872 1.343e-06 2.736e-05
229 NEGATIVE REGULATION OF EMBRYONIC DEVELOPMENT 10 26 1.346e-06 2.736e-05
230 REGULATION OF CELLULAR COMPONENT MOVEMENT 80 771 1.412e-06 2.856e-05
231 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 64 573 1.441e-06 2.891e-05
232 RESPONSE TO ALCOHOL 46 362 1.439e-06 2.891e-05
233 REGULATION OF MICROTUBULE BASED PROCESS 35 243 1.524e-06 3.044e-05
234 COCHLEA MORPHOGENESIS 9 21 1.563e-06 3.109e-05
235 REGULATION OF CELL CYCLE ARREST 21 108 1.653e-06 3.272e-05
236 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 26 154 1.728e-06 3.406e-05
237 CELL CYCLE PHASE TRANSITION 36 255 1.755e-06 3.445e-05
238 MITOTIC DNA INTEGRITY CHECKPOINT 20 100 1.835e-06 3.587e-05
239 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 66 602 1.888e-06 3.676e-05
240 STEM CELL PROLIFERATION 15 60 1.91e-06 3.689e-05
241 REGULATION OF PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 15 60 1.91e-06 3.689e-05
242 NEGATIVE REGULATION OF NUCLEAR DIVISION 13 46 2.069e-06 3.975e-05
243 DNA INTEGRITY CHECKPOINT 25 146 2.084e-06 3.975e-05
244 POSITIVE REGULATION OF EMBRYONIC DEVELOPMENT 11 33 2.084e-06 3.975e-05
245 REGULATION OF PHOSPHATASE ACTIVITY 23 128 2.257e-06 4.287e-05
246 MUSCLE CELL DIFFERENTIATION 34 237 2.345e-06 4.435e-05
247 REGULATION OF BMP SIGNALING PATHWAY 17 77 2.6e-06 4.898e-05
248 EYE DEVELOPMENT 42 326 2.864e-06 5.374e-05
249 SOMITOGENESIS 15 62 2.982e-06 5.551e-05
250 DOPAMINERGIC NEURON DIFFERENTIATION 10 28 2.977e-06 5.551e-05
251 HEART DEVELOPMENT 54 466 3.212e-06 5.955e-05
252 CHROMATIN REMODELING 25 150 3.455e-06 6.379e-05
253 REGULATION OF CYTOPLASMIC TRANSPORT 55 481 3.908e-06 7.187e-05
254 REGULATION OF CELLULAR RESPONSE TO STRESS 72 691 4.114e-06 7.532e-05
255 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 27 171 4.128e-06 7.532e-05
256 EPITHELIAL TO MESENCHYMAL TRANSITION 14 56 4.189e-06 7.561e-05
257 FC EPSILON RECEPTOR SIGNALING PATHWAY 24 142 4.192e-06 7.561e-05
258 POSITIVE REGULATION OF TRANSPORT 91 936 4.193e-06 7.561e-05
259 OSTEOBLAST DEVELOPMENT 8 18 4.363e-06 7.839e-05
260 CELL ACTIVATION 62 568 4.448e-06 7.96e-05
261 POSITIVE REGULATION OF DNA BINDING 12 42 4.502e-06 8.026e-05
262 REGULATION OF ANATOMICAL STRUCTURE SIZE 54 472 4.7e-06 8.347e-05
263 MULTI MULTICELLULAR ORGANISM PROCESS 31 213 4.774e-06 8.447e-05
264 MACROMOLECULAR COMPLEX ASSEMBLY 125 1398 4.962e-06 8.745e-05
265 PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 23 134 5.056e-06 8.877e-05
266 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 45 368 5.228e-06 9.146e-05
267 NEGATIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 19 98 5.342e-06 9.31e-05
268 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 24 144 5.383e-06 9.341e-05
269 REGULATION OF INTRACELLULAR TRANSPORT 66 621 5.4e-06 9.341e-05
270 G1 DNA DAMAGE CHECKPOINT 16 73 5.632e-06 9.705e-05
271 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 13 50 5.756e-06 9.883e-05
272 MULTI ORGANISM REPRODUCTIVE PROCESS 87 891 5.788e-06 9.901e-05
273 RESPONSE TO EXTRACELLULAR STIMULUS 51 441 6.341e-06 0.0001081
274 CELLULAR RESPONSE TO ACID CHEMICAL 27 175 6.435e-06 0.0001093
275 REGULATION OF CELLULAR COMPONENT SIZE 42 337 6.655e-06 0.0001126
276 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 44 360 6.716e-06 0.0001132
277 CONVERGENT EXTENSION 7 14 6.755e-06 0.0001135
278 POSITIVE REGULATION OF CATABOLIC PROCESS 47 395 6.822e-06 0.0001142
279 DORSAL VENTRAL PATTERN FORMATION 18 91 6.995e-06 0.0001167
280 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 19 100 7.275e-06 0.0001209
281 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 30 207 7.359e-06 0.0001219
282 RESPIRATORY SYSTEM DEVELOPMENT 29 197 7.634e-06 0.000126
283 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 31 218 7.74e-06 0.0001273
284 POSITIVE REGULATION OF NEURON DIFFERENTIATION 39 306 8.294e-06 0.0001359
285 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 15 67 8.339e-06 0.0001361
286 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 35 262 8.51e-06 0.0001384
287 PEPTIDYL SERINE MODIFICATION 24 148 8.735e-06 0.0001401
288 SPINDLE CHECKPOINT 9 25 8.721e-06 0.0001401
289 CELL MOTILITY 82 835 8.716e-06 0.0001401
290 LOCALIZATION OF CELL 82 835 8.716e-06 0.0001401
291 REGULATION OF PROTEIN BINDING 26 168 8.961e-06 0.0001423
292 REGULATION OF AXONOGENESIS 26 168 8.961e-06 0.0001423
293 REGULATION OF PROTEIN TARGETING 39 307 8.961e-06 0.0001423
294 REGULATION OF DENDRITE DEVELOPMENT 21 120 9.43e-06 0.0001492
295 ORGANELLE FISSION 55 496 9.694e-06 0.0001529
296 SISTER CHROMATID COHESION 20 111 9.734e-06 0.000153
297 RESPONSE TO ORGANIC CYCLIC COMPOUND 88 917 1.006e-05 0.0001575
298 STEM CELL DIFFERENTIATION 28 190 1.066e-05 0.0001665
299 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 21 121 1.077e-05 0.0001676
300 REGULATION OF GTPASE ACTIVITY 69 673 1.121e-05 0.0001739
301 REGULATION OF MUSCLE TISSUE DEVELOPMENT 19 103 1.137e-05 0.0001751
302 PEPTIDYL AMINO ACID MODIFICATION 82 841 1.136e-05 0.0001751
303 RESPONSE TO GROWTH FACTOR 53 475 1.176e-05 0.0001806
304 COVALENT CHROMATIN MODIFICATION 42 345 1.19e-05 0.0001821
305 POSITIVE REGULATION OF DNA REPLICATION 17 86 1.261e-05 0.0001923
306 PEPTIDYL THREONINE MODIFICATION 12 46 1.266e-05 0.0001924
307 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 45 381 1.285e-05 0.0001948
308 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 19 104 1.313e-05 0.0001984
309 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 52 465 1.333e-05 0.0002007
310 CELLULAR RESPONSE TO HORMONE STIMULUS 59 552 1.426e-05 0.0002141
311 REGULATION OF PROTEIN IMPORT 27 183 1.49e-05 0.0002229
312 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 38 303 1.561e-05 0.0002328
313 REGULATION OF CELL ADHESION 65 629 1.566e-05 0.0002328
314 NEURON PROJECTION GUIDANCE 29 205 1.662e-05 0.0002462
315 NEPHRON DEVELOPMENT 20 115 1.679e-05 0.0002481
316 POSITIVE REGULATION OF NON CANONICAL WNT SIGNALING PATHWAY 6 11 1.695e-05 0.0002495
317 REGULATION OF MUSCLE SYSTEM PROCESS 28 195 1.746e-05 0.0002563
318 ENDODERM DEVELOPMENT 15 71 1.757e-05 0.0002572
319 POSITIVE REGULATION OF KINASE ACTIVITY 53 482 1.771e-05 0.0002582
320 CRANIAL SKELETAL SYSTEM DEVELOPMENT 13 55 1.776e-05 0.0002582
321 PROTEASOMAL PROTEIN CATABOLIC PROCESS 35 271 1.782e-05 0.0002583
322 EPITHELIAL CELL DIFFERENTIATION 54 495 1.85e-05 0.0002673
323 CHROMOSOME SEGREGATION 35 272 1.929e-05 0.000277
324 NUCLEAR CHROMOSOME SEGREGATION 31 228 1.924e-05 0.000277
325 CELL DEATH 93 1001 2.028e-05 0.0002894
326 CENTROMERE COMPLEX ASSEMBLY 12 48 2.026e-05 0.0002894
327 POSITIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 10 34 2.133e-05 0.0003026
328 BRAIN MORPHOGENESIS 10 34 2.133e-05 0.0003026
329 REGULATION OF EPITHELIAL CELL PROLIFERATION 36 285 2.215e-05 0.0003132
330 AXIS SPECIFICATION 17 90 2.355e-05 0.0003311
331 MIDBRAIN DEVELOPMENT 17 90 2.355e-05 0.0003311
332 MUSCLE TISSUE DEVELOPMENT 35 275 2.439e-05 0.0003419
333 CELLULAR RESPONSE TO EXTERNAL STIMULUS 34 264 2.477e-05 0.0003442
334 PANCREAS DEVELOPMENT 15 73 2.494e-05 0.0003442
335 NEGATIVE REGULATION OF CHROMOSOME SEGREGATION 9 28 2.501e-05 0.0003442
336 CELL FATE COMMITMENT INVOLVED IN FORMATION OF PRIMARY GERM LAYER 9 28 2.501e-05 0.0003442
337 NEGATIVE REGULATION OF DENDRITE DEVELOPMENT 9 28 2.501e-05 0.0003442
338 MESODERM DEVELOPMENT 20 118 2.48e-05 0.0003442
339 REGULATION OF OSSIFICATION 26 178 2.545e-05 0.0003494
340 CELLULAR RESPONSE TO RETINOIC ACID 14 65 2.644e-05 0.0003619
341 CELL CYCLE G2 M PHASE TRANSITION 22 138 2.681e-05 0.000364
342 REGULATION OF DEPHOSPHORYLATION 24 158 2.683e-05 0.000364
343 KIDNEY MORPHOGENESIS 16 82 2.67e-05 0.000364
344 DIGESTIVE SYSTEM DEVELOPMENT 23 148 2.703e-05 0.0003656
345 IN UTERO EMBRYONIC DEVELOPMENT 38 311 2.81e-05 0.0003789
346 MESENCHYME DEVELOPMENT 27 190 2.957e-05 0.0003977
347 RESPONSE TO REACTIVE OXYGEN SPECIES 27 191 3.25e-05 0.0004358
348 VASCULATURE DEVELOPMENT 51 469 3.409e-05 0.0004558
349 EMBRYONIC HINDLIMB MORPHOGENESIS 9 29 3.433e-05 0.0004576
350 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 18 102 3.573e-05 0.0004751
351 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 20 121 3.607e-05 0.0004782
352 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 16 84 3.646e-05 0.000482
353 NEGATIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 10 36 3.702e-05 0.000488
354 REGULATION OF MAPK CASCADE 66 660 3.779e-05 0.0004939
355 RESPONSE TO KETONE 26 182 3.761e-05 0.0004939
356 NEGATIVE REGULATION OF PHOSPHORYLATION 47 422 3.785e-05 0.0004939
357 REGULATION OF SISTER CHROMATID SEGREGATION 14 67 3.789e-05 0.0004939
358 POSITIVE REGULATION OF DNA BIOSYNTHETIC PROCESS 13 59 3.954e-05 0.0005139
359 REGULATION OF APOPTOTIC SIGNALING PATHWAY 42 363 4.016e-05 0.0005205
360 RESPONSE TO STEROID HORMONE 53 497 4.088e-05 0.0005271
361 REGULATION OF CIRCADIAN RHYTHM 18 103 4.089e-05 0.0005271
362 REGULATION OF CELLULAR COMPONENT BIOGENESIS 74 767 4.3e-05 0.0005527
363 STRIATED MUSCLE CELL DIFFERENTIATION 25 173 4.337e-05 0.0005544
364 REGULATION OF CELL SUBSTRATE ADHESION 25 173 4.337e-05 0.0005544
365 POSITIVE REGULATION OF GROWTH 31 238 4.468e-05 0.0005696
366 PALLIUM DEVELOPMENT 23 153 4.628e-05 0.0005884
367 CELLULAR RESPONSE TO REACTIVE OXYGEN SPECIES 18 104 4.671e-05 0.0005922
368 HINDLIMB MORPHOGENESIS 10 37 4.8e-05 0.000607
369 POSITIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 30 228 4.869e-05 0.000614
370 POSITIVE REGULATION OF DNA METABOLIC PROCESS 26 185 4.992e-05 0.0006278
371 REGULATION OF COLLATERAL SPROUTING 7 18 5.056e-05 0.0006307
372 QUATERNARY AMMONIUM GROUP TRANSPORT 7 18 5.056e-05 0.0006307
373 UTERUS DEVELOPMENT 7 18 5.056e-05 0.0006307
374 MESENCHYMAL CELL DIFFERENTIATION 21 134 5.248e-05 0.0006529
375 REGULATION OF CELL FATE SPECIFICATION 6 13 5.667e-05 0.0007032
376 DEVELOPMENTAL GROWTH 39 333 5.726e-05 0.0007086
377 KIDNEY EPITHELIUM DEVELOPMENT 20 125 5.813e-05 0.0007174
378 POSITIVE REGULATION OF INTRACELLULAR TRANSPORT 42 370 6.242e-05 0.0007663
379 LYMPHOCYTE DIFFERENTIATION 28 209 6.227e-05 0.0007663
380 PROTEIN LOCALIZATION 148 1805 6.268e-05 0.0007676
381 ESTABLISHMENT OF LOCALIZATION IN CELL 139 1676 6.311e-05 0.0007708
382 MUSCLE ORGAN DEVELOPMENT 34 277 6.633e-05 0.0008079
383 SEX DIFFERENTIATION 33 266 6.846e-05 0.0008317
384 EMBRYONIC CRANIAL SKELETON MORPHOGENESIS 11 46 6.958e-05 0.0008432
385 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 34 278 7.129e-05 0.0008616
386 HINDBRAIN DEVELOPMENT 21 137 7.305e-05 0.0008806
387 LENS FIBER CELL DIFFERENTIATION 8 25 7.376e-05 0.0008868
388 REGULATION OF NON CANONICAL WNT SIGNALING PATHWAY 7 19 7.589e-05 0.0009101
389 NEGATIVE REGULATION OF MOLECULAR FUNCTION 96 1079 7.871e-05 0.0009415
390 NEGATIVE REGULATION OF CELL DEVELOPMENT 36 303 8.101e-05 0.0009665
391 RESPONSE TO NUTRIENT 26 191 8.594e-05 0.001023
392 REGULATION OF KIDNEY DEVELOPMENT 12 55 8.622e-05 0.001023
393 REGULATION OF CELL MATRIX ADHESION 16 90 8.713e-05 0.001029
394 MESONEPHROS DEVELOPMENT 16 90 8.713e-05 0.001029
395 POSITIVE REGULATION OF CELL ADHESION 42 376 8.989e-05 0.001059
396 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 20 129 9.145e-05 0.001075
397 AMINO ACID BETAINE TRANSPORT 6 14 9.411e-05 0.001103
398 POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT 34 282 9.469e-05 0.001107
399 FORELIMB MORPHOGENESIS 10 40 9.899e-05 0.001154
400 OUTFLOW TRACT MORPHOGENESIS 12 56 0.0001038 0.001206
401 CELLULAR COMPONENT DISASSEMBLY 53 515 0.000104 0.001206
402 REGULATION OF CELL DIVISION 33 272 0.0001057 0.001223
403 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 55 541 0.000107 0.001233
404 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 55 541 0.000107 0.001233
405 NEGATIVE REGULATION OF DNA METABOLIC PROCESS 18 111 0.0001123 0.00129
406 PROTEIN STABILIZATION 20 131 0.0001137 0.001303
407 REGULATION OF HORMONE SECRETION 32 262 0.0001178 0.001347
408 REGULATION OF SECRETION 67 699 0.0001189 0.001356
409 FC RECEPTOR SIGNALING PATHWAY 27 206 0.0001215 0.001381
410 REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 33 274 0.0001217 0.001381
411 REGULATION OF NUCLEAR DIVISION 23 163 0.0001248 0.001413
412 REGULATION OF OSTEOBLAST DIFFERENTIATION 18 112 0.0001263 0.001427
413 REGULATION OF GENE EXPRESSION EPIGENETIC 29 229 0.0001283 0.001446
414 LENS DEVELOPMENT IN CAMERA TYPE EYE 13 66 0.0001348 0.001515
415 CELLULAR RESPONSE TO DEXAMETHASONE STIMULUS 8 27 0.0001359 0.00152
416 AXIS ELONGATION 8 27 0.0001359 0.00152
417 POSITIVE REGULATION OF OSSIFICATION 15 84 0.0001362 0.00152
418 CELL SUBSTRATE ADHESION 23 164 0.000137 0.001525
419 REGULATION OF MUSCLE ORGAN DEVELOPMENT 17 103 0.0001381 0.001533
420 IMMUNE SYSTEM PROCESS 158 1984 0.0001487 0.001637
421 SINGLE ORGANISM CELL ADHESION 48 459 0.0001485 0.001637
422 RESPONSE TO STIMULUS INVOLVED IN REGULATION OF MUSCLE ADAPTATION 6 15 0.0001488 0.001637
423 REGULATION OF DNA BIOSYNTHETIC PROCESS 16 94 0.0001484 0.001637
424 NEGATIVE REGULATION OF BMP SIGNALING PATHWAY 10 42 0.0001539 0.001689
425 REGULATION OF PEPTIDE SECRETION 27 209 0.000155 0.001693
426 MODULATION OF SYNAPTIC TRANSMISSION 35 301 0.000155 0.001693
427 REGULATION OF CHROMOSOME SEGREGATION 15 85 0.0001563 0.0017
428 ENDODERM FORMATION 11 50 0.000156 0.0017
429 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 23 166 0.0001647 0.001786
430 NEGATIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 20 135 0.0001731 0.001873
431 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 46 437 0.000174 0.001875
432 BONE REMODELING 9 35 0.0001743 0.001875
433 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 22 156 0.0001749 0.001875
434 POSITIVE REGULATION OF PROTEOLYSIS 40 363 0.0001748 0.001875
435 GASTRULATION WITH MOUTH FORMING SECOND 8 28 0.0001802 0.001928
436 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 52 514 0.0001843 0.001967
437 HEART MORPHOGENESIS 27 212 0.0001965 0.002092
438 POSITIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 31 258 0.000201 0.002135
439 MATERNAL PROCESS INVOLVED IN FEMALE PREGNANCY 12 60 0.000208 0.002205
440 CELL CELL ADHESION 59 608 0.0002159 0.002283
441 GLAND MORPHOGENESIS 16 97 0.0002164 0.002283
442 SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR 19 127 0.0002188 0.002304
443 REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 9 36 0.0002201 0.002306
444 HEAD MORPHOGENESIS 9 36 0.0002201 0.002306
445 RESPONSE TO RETINOIC ACID 17 107 0.0002221 0.002322
446 REGULATION OF PROTEASOMAL UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 21 148 0.0002231 0.002322
447 MALE SEX DIFFERENTIATION 21 148 0.0002231 0.002322
448 REGULATION OF GRANULOCYTE DIFFERENTIATION 6 16 0.000226 0.002337
449 CELL SURFACE RECEPTOR SIGNALING PATHWAY INVOLVED IN HEART DEVELOPMENT 6 16 0.000226 0.002337
450 V D J RECOMBINATION 6 16 0.000226 0.002337
451 RESPONSE TO ACID CHEMICAL 36 319 0.0002275 0.002347
452 BODY MORPHOGENESIS 10 44 0.0002325 0.002391
453 REGULATION OF STEM CELL PROLIFERATION 15 88 0.0002328 0.002391
454 POSITIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 8 29 0.0002358 0.002417
455 POSITIVE REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 25 192 0.0002364 0.002418
456 REGULATION OF PROTEASOMAL PROTEIN CATABOLIC PROCESS 24 181 0.0002371 0.002419
457 CYTOSKELETON ORGANIZATION 76 838 0.0002449 0.002483
458 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 43 406 0.0002446 0.002483
459 RESPONSE TO DRUG 45 431 0.0002445 0.002483
460 SECOND MESSENGER MEDIATED SIGNALING 22 160 0.0002527 0.002556
461 DNA METABOLIC PROCESS 70 758 0.0002547 0.002571
462 MACROMOLECULAR COMPLEX DISASSEMBLY 24 182 0.0002578 0.002597
463 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 48 470 0.0002585 0.002597
464 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 27 216 0.0002671 0.002678
465 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 16 99 0.0002754 0.00275
466 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 16 99 0.0002754 0.00275
467 CELLULAR RESPONSE TO DNA DAMAGE STIMULUS 67 720 0.0002775 0.002765
468 TELENCEPHALON DEVELOPMENT 28 228 0.0002791 0.002775
469 NEGATIVE REGULATION OF LOCOMOTION 31 263 0.0002829 0.002807
470 CELL FATE SPECIFICATION 13 71 0.0002895 0.002863
471 IMMUNE RESPONSE REGULATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 36 323 0.0002898 0.002863
472 REGULATION OF SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR 22 162 0.0003019 0.002976
473 REGULATION OF ACTIN FILAMENT BASED PROCESS 35 312 0.0003093 0.003042
474 REGULATION OF JUN KINASE ACTIVITY 14 81 0.0003208 0.003149
475 REGULATION OF CHROMATIN ORGANIZATION 21 152 0.0003236 0.00317
476 NEGATIVE REGULATION OF BINDING 19 131 0.0003285 0.003211
477 ESTABLISHMENT OF TISSUE POLARITY 6 17 0.0003315 0.003234
478 REGULATION OF CARTILAGE DEVELOPMENT 12 63 0.0003357 0.003267
479 REGULATION OF CHONDROCYTE DIFFERENTIATION 10 46 0.0003422 0.003324
480 REGULATION OF PROTEIN COMPLEX ASSEMBLY 40 375 0.0003431 0.003326
481 CELL CYCLE G1 S PHASE TRANSITION 17 111 0.0003475 0.003355
482 G1 S TRANSITION OF MITOTIC CELL CYCLE 17 111 0.0003475 0.003355
483 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 25 197 0.0003519 0.00339
484 CELL CELL SIGNALING 70 767 0.0003568 0.00343
485 TAXIS 47 464 0.0003586 0.00344
486 BLOOD VESSEL MORPHOGENESIS 39 364 0.0003701 0.003543
487 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 28 232 0.0003717 0.003551
488 REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 13 73 0.0003843 0.003664
489 NEGATIVE REGULATION OF CYTOSKELETON ORGANIZATION 27 221 0.0003862 0.003675
490 REGULATION OF PEPTIDE TRANSPORT 30 256 0.0003886 0.00369
491 LEUKOCYTE DIFFERENTIATION 33 292 0.0003966 0.003759
492 RESPONSE TO MECHANICAL STIMULUS 26 210 0.0003993 0.003777
493 POSITIVE REGULATION OF NEURON APOPTOTIC PROCESS 10 47 0.0004114 0.003883
494 CELLULAR RESPONSE TO EXTRACELLULAR STIMULUS 24 188 0.0004191 0.003946
495 COCHLEA DEVELOPMENT 9 39 0.0004207 0.003946
496 EMBRYO IMPLANTATION 9 39 0.0004207 0.003946
497 REGULATION OF EPITHELIAL CELL MIGRATION 22 166 0.0004262 0.00399
498 NEPHRON EPITHELIUM DEVELOPMENT 15 93 0.0004323 0.004039
499 ORGANIC ACID TRANSMEMBRANE TRANSPORT 16 103 0.0004363 0.004068
500 POSITIVE REGULATION BY HOST OF VIRAL TRANSCRIPTION 5 12 0.0004397 0.004084
501 REGULATION OF WNT SIGNALING PATHWAY PLANAR CELL POLARITY PATHWAY 5 12 0.0004397 0.004084
502 REGULATION OF DENDRITE MORPHOGENESIS 13 74 0.0004409 0.004086
503 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 11 56 0.0004462 0.004127
504 NEGATIVE REGULATION OF AXONOGENESIS 12 65 0.0004533 0.004185
505 CYTOKINESIS 14 84 0.0004718 0.00434
506 INOSITOL PHOSPHATE MEDIATED SIGNALING 6 18 0.000472 0.00434
507 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 10 48 0.0004919 0.004506
508 EMBRYONIC FORELIMB MORPHOGENESIS 8 32 0.0004916 0.004506
509 RESPONSE TO CARBOHYDRATE 22 168 0.0005036 0.004604
510 STEROID HORMONE MEDIATED SIGNALING PATHWAY 18 125 0.0005093 0.004647
511 POSITIVE REGULATION OF CELL MATRIX ADHESION 9 40 0.0005141 0.004672
512 ENDODERMAL CELL DIFFERENTIATION 9 40 0.0005141 0.004672
513 MYOTUBE DIFFERENTIATION 11 57 0.0005232 0.004745
514 HISTONE PHOSPHORYLATION 7 25 0.000526 0.004762
515 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 24 191 0.0005288 0.004778
516 NEGATIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 19 136 0.0005307 0.004785
517 CHEMICAL HOMEOSTASIS 77 874 0.0005321 0.004787
518 REGULATION OF STRIATED MUSCLE CELL DIFFERENTIATION 14 85 0.000534 0.004787
519 POSITIVE REGULATION OF CHROMATIN MODIFICATION 14 85 0.000534 0.004787
520 REGULATION OF HOMEOSTATIC PROCESS 45 447 0.0005403 0.004834
521 CEREBRAL CORTEX DEVELOPMENT 16 105 0.0005432 0.004852
522 REGULATION OF NEURON APOPTOTIC PROCESS 24 192 0.0005706 0.005077
523 PROTEIN AUTOPHOSPHORYLATION 24 192 0.0005706 0.005077
524 GROWTH 42 410 0.0005736 0.005094
525 SKELETAL MUSCLE ORGAN DEVELOPMENT 19 137 0.000582 0.005158
526 PROTEIN CATABOLIC PROCESS 55 579 0.0005842 0.005166
527 REGULATION OF SMOOTH MUSCLE CELL MIGRATION 10 49 0.0005851 0.005166
528 POSITIVE REGULATION OF CELL GROWTH 20 148 0.0005932 0.005228
529 REGULATION OF JNK CASCADE 21 159 0.0005965 0.005246
530 REGULATION OF FAT CELL DIFFERENTIATION 16 106 0.0006047 0.005299
531 POSITIVE REGULATION OF NEURON DEATH 12 67 0.0006039 0.005299
532 SIGNAL TRANSDUCTION IN RESPONSE TO DNA DAMAGE 15 96 0.0006113 0.005337
533 CARDIOCYTE DIFFERENTIATION 15 96 0.0006113 0.005337
534 POSITIVE REGULATION OF HISTONE METHYLATION 8 33 0.000615 0.005349
535 RESPONSE TO DEXAMETHASONE 8 33 0.000615 0.005349
536 POSITIVE REGULATION OF BINDING 18 127 0.0006179 0.005364
537 NEGATIVE REGULATION OF FAT CELL DIFFERENTIATION 9 41 0.0006238 0.005405
538 PEPTIDYL LYSINE MODIFICATION 34 312 0.0006324 0.005469
539 SPECIFICATION OF SYMMETRY 17 117 0.0006489 0.005601
540 REGULATION OF CARDIAC MUSCLE CELL DIFFERENTIATION 6 19 0.0006548 0.005642
541 REGULATION OF METAL ION TRANSPORT 35 325 0.000658 0.005659
542 REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO MITOCHONDRION 18 128 0.0006793 0.005812
543 TISSUE REMODELING 14 87 0.0006794 0.005812
544 ENDODERMAL CELL FATE COMMITMENT 5 13 0.0006792 0.005812
545 MESODERMAL CELL DIFFERENTIATION 7 26 0.0006827 0.005818
546 REGULATION OF CELL FATE COMMITMENT 7 26 0.0006827 0.005818
547 REGULATION OF HORMONE LEVELS 47 478 0.0006877 0.00585
548 REGULATION OF ADHERENS JUNCTION ORGANIZATION 10 50 0.0006924 0.005879
549 REGULATION OF CELL JUNCTION ASSEMBLY 12 68 0.0006937 0.005879
550 REGULATION OF MITOCHONDRION ORGANIZATION 26 218 0.0007079 0.005989
551 CELLULAR RESPONSE TO OXIDATIVE STRESS 23 184 0.0007356 0.006212
552 RENAL TUBULE DEVELOPMENT 13 78 0.0007429 0.006262
553 DENDRITE MORPHOGENESIS 9 42 0.0007519 0.006327
554 REGULATION OF MESENCHYMAL CELL PROLIFERATION 8 34 0.0007621 0.006396
555 RESPONSE TO VITAMIN 15 98 0.0007629 0.006396
556 REGULATION OF RESPONSE TO STRESS 118 1468 0.000765 0.006402
557 CELL JUNCTION ORGANIZATION 23 185 0.0007932 0.0066
558 MITOTIC SPINDLE ORGANIZATION 12 69 0.0007944 0.0066
559 POSITIVE REGULATION OF AXONOGENESIS 12 69 0.0007944 0.0066
560 RESPONSE TO ACTIVITY 12 69 0.0007944 0.0066
561 RESPONSE TO EXTERNAL STIMULUS 142 1821 0.0007989 0.006627
562 CHONDROCYTE DIFFERENTIATION 11 60 0.0008234 0.006817
563 RESPONSE TO HYDROGEN PEROXIDE 16 109 0.0008258 0.006825
564 REGULATION OF MUSCLE CELL DIFFERENTIATION 20 152 0.0008352 0.006891
565 DENDRITE DEVELOPMENT 13 79 0.000841 0.006901
566 NEGATIVE REGULATION OF PROTEIN BINDING 13 79 0.000841 0.006901
567 BONE MORPHOGENESIS 13 79 0.000841 0.006901
568 LYMPHOCYTE ACTIVATION 36 342 0.0008438 0.006912
569 MICROTUBULE BASED PROCESS 50 522 0.0008474 0.00693
570 ANGIOGENESIS 32 293 0.0008664 0.007073
571 REGULATION OF PROTEIN STABILITY 26 221 0.0008685 0.007077
572 DEVELOPMENTAL INDUCTION 7 27 0.000874 0.007085
573 REGULATION OF PROTEIN LOCALIZATION TO CELL SURFACE 7 27 0.000874 0.007085
574 POSITIVE REGULATION OF MESENCHYMAL CELL PROLIFERATION 7 27 0.000874 0.007085
575 REGULATION OF TRANSPORTER ACTIVITY 24 198 0.000887 0.007161
576 MIDDLE EAR MORPHOGENESIS 6 20 0.000888 0.007161
577 INTRACELLULAR LIPID TRANSPORT 6 20 0.000888 0.007161
578 NEGATIVE REGULATION OF STEM CELL DIFFERENTIATION 9 43 0.0009007 0.007226
579 REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 9 43 0.0009007 0.007226
580 REGULATION OF TELOMERASE ACTIVITY 9 43 0.0009007 0.007226
581 NEURAL PRECURSOR CELL PROLIFERATION 12 70 0.000907 0.007264
582 POSITIVE REGULATION OF LIGASE ACTIVITY 16 110 0.0009133 0.007302
583 CELLULAR RESPONSE TO HYDROGEN PEROXIDE 11 61 0.0009507 0.007587
584 MULTICELLULAR ORGANISM REPRODUCTION 68 768 0.0009695 0.007725
585 REGULATION OF ION TRANSPORT 55 592 0.000982 0.007811
586 EMBRYONIC SKELETAL JOINT DEVELOPMENT 5 14 0.001004 0.00796
587 POSITIVE REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 5 14 0.001004 0.00796
588 POSTTRANSCRIPTIONAL REGULATION OF GENE EXPRESSION 44 448 0.001026 0.008123
589 ADHERENS JUNCTION ORGANIZATION 12 71 0.001033 0.008157
590 METANEPHROS DEVELOPMENT 13 81 0.00107 0.008423
591 REGULATION OF FIBROBLAST PROLIFERATION 13 81 0.00107 0.008423
592 MITOTIC SISTER CHROMATID SEGREGATION 14 91 0.001072 0.00843
593 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 19 144 0.001076 0.008446
594 REGULATION OF SMOOTHENED SIGNALING PATHWAY 11 62 0.001094 0.008568
595 VENTRICULAR SEPTUM MORPHOGENESIS 7 28 0.001105 0.008615
596 MORPHOGENESIS OF A POLARIZED EPITHELIUM 7 28 0.001105 0.008615
597 REGULATION OF MICROTUBULE POLYMERIZATION OR DEPOLYMERIZATION 22 178 0.001102 0.008615
598 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 10 53 0.001115 0.008663
599 MESONEPHRIC TUBULE MORPHOGENESIS 10 53 0.001115 0.008663
600 POSITIVE REGULATION OF MITOCHONDRION ORGANIZATION 21 167 0.001134 0.008797
601 POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 8 36 0.001141 0.008833
602 MICROTUBULE CYTOSKELETON ORGANIZATION 36 348 0.001152 0.008876
603 ENDOCRINE SYSTEM DEVELOPMENT 17 123 0.001151 0.008876
604 T CELL DIFFERENTIATION 17 123 0.001151 0.008876
605 BONE DEVELOPMENT 20 156 0.001158 0.008904
606 SYNAPSE ORGANIZATION 19 145 0.00117 0.008986
607 REGULATION OF GENE SILENCING BY RNA 6 21 0.00118 0.008988
608 DECIDUALIZATION 6 21 0.00118 0.008988
609 POSITIVE REGULATION OF ADHERENS JUNCTION ORGANIZATION 6 21 0.00118 0.008988
610 BONE RESORPTION 6 21 0.00118 0.008988
611 REGULATION OF POSTTRANSCRIPTIONAL GENE SILENCING 6 21 0.00118 0.008988
612 POSITIVE REGULATION OF JUN KINASE ACTIVITY 11 63 0.001254 0.009535
613 NEGATIVE REGULATION OF CATABOLIC PROCESS 24 203 0.001257 0.009542
614 LEUKOCYTE ACTIVATION 41 414 0.001279 0.009689
615 STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 15 103 0.001287 0.009738
NumGOOverlapSizeP ValueAdj. P Value
1 BETA CATENIN BINDING 30 84 4.254e-16 1.317e-13
2 WNT PROTEIN BINDING 19 31 4.183e-16 1.317e-13
3 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 61 315 3.418e-16 1.317e-13
4 WNT ACTIVATED RECEPTOR ACTIVITY 16 22 1.488e-15 3.455e-13
5 REGULATORY REGION NUCLEIC ACID BINDING 108 818 7.975e-15 1.482e-12
6 ENZYME BINDING 184 1737 1.14e-14 1.764e-12
7 SEQUENCE SPECIFIC DNA BINDING 126 1037 2.248e-14 2.983e-12
8 FRIZZLED BINDING 18 36 3.199e-13 3.714e-11
9 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 45 226 9.777e-13 1.009e-10
10 DOUBLE STRANDED DNA BINDING 97 764 2.146e-12 1.993e-10
11 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 84 629 4.953e-12 3.834e-10
12 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 55 328 4.598e-12 3.834e-10
13 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 130 1199 3.175e-11 2.269e-09
14 CORE PROMOTER PROXIMAL REGION DNA BINDING 56 371 2.012e-10 1.335e-08
15 PROTEIN SERINE THREONINE KINASE ACTIVITY 63 445 2.262e-10 1.401e-08
16 TRANSCRIPTION FACTOR BINDING 69 524 7.722e-10 4.483e-08
17 PROTEIN KINASE ACTIVITY 79 640 9.86e-10 5.388e-08
18 KINASE ACTIVITY 96 842 1.106e-09 5.708e-08
19 MACROMOLECULAR COMPLEX BINDING 137 1399 8.299e-09 4.058e-07
20 RIBONUCLEOTIDE BINDING 169 1860 2.844e-08 1.321e-06
21 ADENYL NUCLEOTIDE BINDING 143 1514 3.759e-08 1.663e-06
22 KINASE BINDING 70 606 1.293e-07 5.458e-06
23 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 101 992 1.41e-07 5.695e-06
24 CYTOSKELETAL PROTEIN BINDING 84 819 1.229e-06 4.759e-05
25 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 65 588 1.704e-06 6.331e-05
26 PROTEIN DOMAIN SPECIFIC BINDING 67 624 3.244e-06 0.0001159
27 CORE PROMOTER BINDING 25 152 4.412e-06 0.0001464
28 CHROMATIN BINDING 51 435 4.295e-06 0.0001464
29 RECEPTOR BINDING 130 1476 6.733e-06 0.0002157
30 MOLECULAR FUNCTION REGULATOR 121 1353 7.046e-06 0.0002182
31 RECEPTOR REGULATOR ACTIVITY 12 45 9.894e-06 0.0002965
32 RECEPTOR ACTIVATOR ACTIVITY 10 32 1.172e-05 0.0003403
33 PROTEIN PHOSPHATASE TYPE 2A REGULATOR ACTIVITY 8 21 1.724e-05 0.0004853
34 RECEPTOR AGONIST ACTIVITY 7 16 2.023e-05 0.0005527
35 ACTIVATING TRANSCRIPTION FACTOR BINDING 13 57 2.677e-05 0.0007104
36 PROTEIN COMPLEX BINDING 87 935 3.561e-05 0.0009189
37 ENHANCER BINDING 17 93 3.663e-05 0.0009197
38 TRANSCRIPTION COACTIVATOR ACTIVITY 36 296 4.981e-05 0.001218
39 PROTEIN DIMERIZATION ACTIVITY 102 1149 5.126e-05 0.001221
40 ARMADILLO REPEAT DOMAIN BINDING 6 13 5.667e-05 0.001316
41 UBIQUITIN LIKE PROTEIN LIGASE BINDING 33 264 5.898e-05 0.001336
42 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR BINDING 6 15 0.0001488 0.003292
43 RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 17 104 0.0001559 0.003368
44 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 23 168 0.0001972 0.004165
45 G PROTEIN COUPLED RECEPTOR BINDING 31 259 0.0002155 0.004448
46 TUBULIN BINDING 32 273 0.0002518 0.005085
47 I SMAD BINDING 5 11 0.0002699 0.005335
48 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II DISTAL ENHANCER SEQUENCE SPECIFIC BINDING 15 90 0.0003001 0.005809
49 CELL ADHESION MOLECULE BINDING 24 186 0.0003576 0.006779
50 GAMMA CATENIN BINDING 5 12 0.0004397 0.00817
51 INTEGRIN BINDING 16 105 0.0005432 0.009896
NumGOOverlapSizeP ValueAdj. P Value
1 WNT SIGNALOSOME 10 11 6.436e-12 3.758e-09
2 NEURON PART 134 1265 7.624e-11 2.226e-08
3 CHROMOSOME 102 880 1.274e-10 2.264e-08
4 CHROMATIN 63 441 1.55e-10 2.264e-08
5 CELL PROJECTION 172 1786 2.785e-10 3.253e-08
6 CELL PROJECTION PART 106 946 3.858e-10 3.755e-08
7 BETA CATENIN DESTRUCTION COMPLEX 10 14 4.952e-10 4.131e-08
8 SYNAPSE 88 754 1.809e-09 1.321e-07
9 MICROTUBULE CYTOSKELETON 112 1068 5.569e-09 3.613e-07
10 EXCITATORY SYNAPSE 35 197 7.675e-09 4.482e-07
11 PCG PROTEIN COMPLEX 15 43 1.436e-08 7.625e-07
12 NEURON PROJECTION 100 942 2.094e-08 1.019e-06
13 CHROMOSOME CENTROMERIC REGION 31 174 5.096e-08 2.126e-06
14 NUCLEAR CHROMATIN 43 291 4.784e-08 2.126e-06
15 TRANSCRIPTION FACTOR COMPLEX 43 298 9.555e-08 3.72e-06
16 CYTOSKELETON 172 1967 2.855e-07 1.042e-05
17 NEURONAL POSTSYNAPTIC DENSITY 15 53 3.346e-07 1.149e-05
18 EUCHROMATIN 11 31 1.02e-06 3.308e-05
19 LAMELLIPODIUM 28 172 1.485e-06 4.565e-05
20 CYTOSKELETAL PART 130 1436 1.666e-06 4.863e-05
21 NUCLEAR CHROMOSOME 59 523 2.699e-06 7.506e-05
22 SYNAPSE PART 66 610 2.964e-06 7.869e-05
23 SPINDLE 38 289 5.19e-06 0.0001318
24 PROTEIN PHOSPHATASE TYPE 2A COMPLEX 8 20 1.127e-05 0.0002742
25 CHROMOSOMAL REGION 40 330 2.107e-05 0.0004558
26 CELL JUNCTION 104 1151 2.106e-05 0.0004558
27 ESC E Z COMPLEX 7 16 2.023e-05 0.0004558
28 TRANSCRIPTIONAL REPRESSOR COMPLEX 15 74 2.956e-05 0.0006165
29 NUCLEOPLASM PART 70 708 3.192e-05 0.0006429
30 SOMATODENDRITIC COMPARTMENT 65 650 4.32e-05 0.0008409
31 POSTSYNAPSE 43 378 4.879e-05 0.0009191
32 CELL LEADING EDGE 40 350 7.969e-05 0.001454
33 METHYLTRANSFERASE COMPLEX 16 90 8.713e-05 0.001542
34 CATALYTIC COMPLEX 92 1038 0.000127 0.002181
35 MICROTUBULE ORGANIZING CENTER 61 623 0.0001329 0.002218
36 FILOPODIUM 16 94 0.0001484 0.002343
37 CELL SURFACE 71 757 0.0001457 0.002343
38 PERINUCLEAR REGION OF CYTOPLASM 62 642 0.000172 0.002576
39 CENTROSOME 50 487 0.0001709 0.002576
40 NUCLEAR TRANSCRIPTION FACTOR COMPLEX 19 127 0.0002188 0.003195
41 HISTONE METHYLTRANSFERASE COMPLEX 13 71 0.0002895 0.004123
42 KINETOCHORE 18 120 0.0003068 0.004266
43 MITOTIC SPINDLE 11 55 0.0003789 0.005146
44 NUCLEAR EUCHROMATIN 7 24 0.0003994 0.005301
45 MICROTUBULE 42 405 0.0004462 0.005764
46 MICROTUBULE ASSOCIATED COMPLEX 20 145 0.000454 0.005764
47 FILOPODIUM MEMBRANE 6 18 0.000472 0.005865
48 PHOSPHATASE COMPLEX 10 48 0.0004919 0.005985
49 CLATHRIN COATED VESICLE 21 157 0.0005033 0.005999
50 HETEROCHROMATIN 12 67 0.0006039 0.007054
51 SITE OF POLARIZED GROWTH 20 149 0.0006472 0.007411
52 SCF UBIQUITIN LIGASE COMPLEX 8 34 0.0007621 0.008559
53 AXON 42 418 0.0008454 0.009316

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Wnt_signaling_pathway_hsa04310 110 146 1.58e-103 8.214e-102
2 Hippo_signaling_pathway_hsa04390 57 154 2.441e-30 6.347e-29
3 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 42 139 7.435e-19 1.289e-17
4 Cell_cycle_hsa04110 35 124 6.242e-15 8.114e-14
5 Oocyte_meiosis_hsa04114 33 124 2.339e-13 2.433e-12
6 mTOR_signaling_pathway_hsa04150 35 151 3.563e-12 3.088e-11
7 Adherens_junction_hsa04520 22 72 1.212e-10 9.004e-10
8 Cellular_senescence_hsa04218 33 160 3.978e-10 2.586e-09
9 AMPK_signaling_pathway_hsa04152 25 121 5.014e-08 2.897e-07
10 FoxO_signaling_pathway_hsa04068 26 132 7.568e-08 3.935e-07
11 Hedgehog_signaling_pathway_hsa04340 14 47 4.11e-07 1.943e-06
12 Sphingolipid_signaling_pathway_hsa04071 23 118 5.125e-07 2.221e-06
13 Focal_adhesion_hsa04510 31 199 1.107e-06 4.429e-06
14 ErbB_signaling_pathway_hsa04012 18 85 2.52e-06 9.362e-06
15 Tight_junction_hsa04530 27 170 3.684e-06 1.277e-05
16 PI3K_Akt_signaling_pathway_hsa04151 43 352 8.627e-06 2.775e-05
17 TGF_beta_signaling_pathway_hsa04350 17 84 9.072e-06 2.775e-05
18 MAPK_signaling_pathway_hsa04010 37 295 2.006e-05 5.795e-05
19 p53_signaling_pathway_hsa04115 14 68 4.51e-05 0.0001234
20 cAMP_signaling_pathway_hsa04024 27 198 6.147e-05 0.0001598
21 Calcium_signaling_pathway_hsa04020 25 182 0.0001007 0.0002492
22 cGMP_PKG_signaling_pathway_hsa04022 22 163 0.0003295 0.0007789
23 VEGF_signaling_pathway_hsa04370 11 59 0.0007106 0.001607
24 Phosphatidylinositol_signaling_system_hsa04070 15 99 0.00085 0.001842
25 Apelin_signaling_pathway_hsa04371 18 137 0.00151 0.003141
26 Ras_signaling_pathway_hsa04014 26 232 0.001758 0.003449
27 Autophagy_animal_hsa04140 17 128 0.001791 0.003449
28 Notch_signaling_pathway_hsa04330 9 48 0.002043 0.003795
29 Mitophagy_animal_hsa04137 10 65 0.005326 0.009551
30 HIF_1_signaling_pathway_hsa04066 13 100 0.007065 0.01225
31 Regulation_of_actin_cytoskeleton_hsa04810 21 208 0.01453 0.02437
32 Rap1_signaling_pathway_hsa04015 20 206 0.02449 0.0398
33 ECM_receptor_interaction_hsa04512 10 82 0.02548 0.04015
34 Phospholipase_D_signaling_pathway_hsa04072 15 146 0.03059 0.04678
35 Gap_junction_hsa04540 10 88 0.03904 0.05676
36 Endocytosis_hsa04144 22 244 0.0393 0.05676
37 Apoptosis_multiple_species_hsa04215 5 33 0.04617 0.06488
38 TNF_signaling_pathway_hsa04668 10 108 0.1168 0.1599
39 Necroptosis_hsa04217 13 164 0.1918 0.2558
40 Apoptosis_hsa04210 11 138 0.2117 0.2752
41 Ferroptosis_hsa04216 4 40 0.2201 0.2792
42 Hippo_signaling_pathway_multiple_species_hsa04392 3 29 0.2538 0.3142
43 Jak_STAT_signaling_pathway_hsa04630 12 162 0.2732 0.3304
44 ABC_transporters_hsa02010 4 45 0.2872 0.3395
45 Autophagy_other_hsa04136 3 32 0.304 0.3513
46 Cell_adhesion_molecules_.CAMs._hsa04514 9 145 0.5146 0.5817
47 Lysosome_hsa04142 7 123 0.618 0.6838
48 NF_kappa_B_signaling_pathway_hsa04064 5 95 0.6861 0.7433
49 Phagosome_hsa04145 8 152 0.7046 0.7477
50 Peroxisome_hsa04146 2 83 0.9642 0.9951
51 Cytokine_cytokine_receptor_interaction_hsa04060 8 270 0.9933 0.9951
52 Neuroactive_ligand_receptor_interaction_hsa04080 8 278 0.9951 0.9951

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1 LDLRAD4-AS1 hsa-miR-106b-5p;hsa-miR-132-3p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-301a-3p;hsa-miR-3127-5p;hsa-miR-454-3p;hsa-miR-589-3p 10 FZD4 Sponge network -3.366 0 -0.346 0.01097 0.404
2 AC005550.3 hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-183-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-21-5p;hsa-miR-301a-3p;hsa-miR-362-3p;hsa-miR-92a-3p;hsa-miR-92b-3p 10 DAAM1 Sponge network -2.571 0.00132 -0.82 3.0E-5 0.394
3

RP11-166D19.1

 hsa-miR-106b-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-301a-3p;hsa-miR-32-3p;hsa-miR-32-5p;hsa-miR-324-3p;hsa-miR-330-5p;hsa-miR-361-5p;hsa-miR-484;hsa-miR-589-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-92a-3p;hsa-miR-940 18 FZD4 Sponge network -0.244 0.28835 -0.346 0.01097 0.384
4

MAGI2-AS3

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1266-5p;hsa-miR-15b-5p;hsa-miR-17-5p;hsa-miR-193a-3p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-425-5p;hsa-miR-589-3p;hsa-miR-616-5p;hsa-miR-9-5p;hsa-miR-92a-3p;hsa-miR-93-5p 16 CCND1 Sponge network -1.801 0 -0.902 1.0E-5 0.359
5 RP11-12A2.3 hsa-let-7d-5p;hsa-miR-106b-5p;hsa-miR-132-3p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-301a-3p;hsa-miR-330-5p;hsa-miR-92a-3p 11 FZD4 Sponge network -4.779 0 -0.346 0.01097 0.342
6 RP11-7F17.3 hsa-let-7d-5p;hsa-miR-106b-5p;hsa-miR-132-3p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-301a-3p;hsa-miR-3127-5p;hsa-miR-324-3p;hsa-miR-330-5p;hsa-miR-940 12 FZD4 Sponge network -0.873 0.00204 -0.346 0.01097 0.341
7 RP11-480I12.7 hsa-miR-142-5p;hsa-miR-146a-5p;hsa-miR-150-5p;hsa-miR-218-5p;hsa-miR-22-5p;hsa-miR-2355-3p;hsa-miR-24-2-5p;hsa-miR-330-3p;hsa-miR-381-3p;hsa-miR-495-3p 10 PRKCA Sponge network 2.03 0 0.663 0 0.332
8 MIR497HG hsa-miR-106b-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-301a-3p;hsa-miR-32-3p;hsa-miR-324-3p;hsa-miR-589-3p;hsa-miR-940 11 FZD4 Sponge network -0.886 0.00689 -0.346 0.01097 0.313
9 TOB1-AS1 hsa-miR-142-5p;hsa-miR-146a-5p;hsa-miR-150-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-181c-5p;hsa-miR-218-5p;hsa-miR-2355-3p;hsa-miR-330-3p;hsa-miR-450b-5p 10 PRKCA Sponge network 0.811 0 0.663 0 0.308
10 LINC00261 hsa-miR-106b-5p;hsa-miR-132-3p;hsa-miR-21-5p;hsa-miR-301a-3p;hsa-miR-3127-5p;hsa-miR-324-3p;hsa-miR-330-5p;hsa-miR-454-3p;hsa-miR-589-3p;hsa-miR-629-3p;hsa-miR-940 11 FZD4 Sponge network -1.194 0 -0.346 0.01097 0.3
11 CASC2 hsa-miR-107;hsa-miR-148b-3p;hsa-miR-17-3p;hsa-miR-192-3p;hsa-miR-193a-3p;hsa-miR-194-3p;hsa-miR-194-5p;hsa-miR-21-5p;hsa-miR-362-5p;hsa-miR-548j-5p;hsa-miR-885-5p 11 NFAT5 Sponge network -0.596 0.00187 -0.326 0.00164 0.281
12 RP11-539I5.1 hsa-miR-107;hsa-miR-130b-3p;hsa-miR-17-5p;hsa-miR-194-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-30b-3p;hsa-miR-30d-5p;hsa-miR-30e-5p;hsa-miR-32-3p 11 FZD3 Sponge network -1.111 0.02467 -0.432 0.07605 0.259
13 SMIM2-AS1 hsa-let-7d-5p;hsa-miR-106b-5p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-301a-3p;hsa-miR-3127-5p;hsa-miR-330-5p;hsa-miR-589-3p;hsa-miR-629-3p;hsa-miR-940;hsa-miR-98-5p 13 FZD4 Sponge network -0.66 0.00587 -0.346 0.01097 0.253
14

RP11-166D19.1

 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1266-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-193a-3p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-425-5p;hsa-miR-589-3p;hsa-miR-616-5p;hsa-miR-92a-3p;hsa-miR-942-5p 17 CCND1 Sponge network -0.244 0.28835 -0.902 1.0E-5 0.253

Quest ID: 5d811e9daaa9621bcf47d4c3f94d376c